journal
MENU ▼
Read by QxMD icon Read
search

International Journal of Immunogenetics

journal
https://www.readbyqxmd.com/read/30447055/distribution-of-abo-and-rhd-blood-group-antigens-in-blood-donors-in-burkina-faso
#1
Salam Sawadogo, Koumpingnin Nebie, Tieba Millogo, Eléonore Kafando, Abdoul-Guyani Sawadogo, Honorine Dahourou, Fauceny Traore, Siaka Ouattara, Oumarou Ouedraogo, Kisito Kienou, Yonli Yentema Dieudonné, Véronique Deneys
Geographical distribution of ABO and RHD antigens is important for blood transfusion services and population genetics studies. There are few data on this topic in Burkina Faso, a multi-ethnic country. Our study aims at reporting phenotypic and allelic frequencies of ABO and RHD blood groups among voluntary blood donors from various ethnical regions of Burkina Faso. We conducted a cross-sectional study including 81,486 blood donors. ABO allelic frequencies were determined using the Bernstein method. Differences in phenotypic distribution of blood groups were assessed using the chi-square test; a p value <0...
November 17, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/30430731/interleukin-10-gene-promoter-polymorphisms-rs1800896-rs1800871-and-rs1800872-and-haplotypes-are-associated-with-the-activity-of-systemic-lupus-erythematosus-and-il10-levels-in-an-iranian-population
#2
Saeed Mohammadi, Marie Saghaeian Jazi, Mojtaba Zare Ebrahimabad, Farnaz Eghbalpour, Nafiseh Abdolahi, Alijan Tabarraei, Yaghoub Yazdani
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with unknown aetiology. According to the role of interleukin 10 (IL10) in SLE pathogenesis, the genetic alterations in its promoter region could be associated with elevated IL10 levels and exacerbated disease. Here, we investigated the association of genotype and haplotype frequencies of three IL10 gene promoter polymorphisms with susceptibility to SLE, IL10 plasma levels and disease activity of patients in an Iranian population. A total of 116 SLE patients and 131 healthy subjects were enrolled...
November 15, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/30387553/population-genetics-of-the-abo-locus-within-the-rhesus-macaca-mulatta-and-cynomolgus-m-fascicularis-macaque-hybrid-zone
#3
Robert F Oldt, Sreetharan Kanthaswamy, Mae Montes, Laura Schumann, Jose Grijalva, Srichan Bunlungsup, Paul Houghton, David Glenn Smith, Suchinda Malaivijitnond
Knowledge of the macaque ABO blood group system has been critical in the development of nonhuman primates (NHPs) as a translational model. Serving not only as a useful homologue of the disease-linked ABO system in humans, macaque ABO blood groups must be typed in colonies prior to performing experimental procedures requiring blood transfusion or transplantation. While the rates of blood type incompatibility and the distributions of A, B and AB blood groups are known in large samples of rhesus (Macaca mulatta) and cynomolgus (M...
November 2, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/30375192/nomenclature-for-factors-of-the-hla-system-update-july-2018
#4
Steven G E Marsh
No abstract text is available yet for this article.
October 30, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/30375172/nomenclature-for-factors-of-the-hla-system-update-august-2018
#5
Steven G E Marsh
No abstract text is available yet for this article.
October 30, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/30358139/nomenclature-for-factors-of-the-hla-system-update-september-2018
#6
Steven G E Marsh
No abstract text is available yet for this article.
October 25, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/30264444/association-of-nod-like-receptor-protein-3-single-nucleotide-gene-polymorphisms-and-expression-with-the-susceptibility-to-relapsing-remitting-multiple-sclerosis
#7
Danyal Imani, Amirreza Azimi, Zahra Salehi, Nima Rezaei, Rahimeh Emamnejad, Maryam Sadr, Maryam Izad
Nod-like receptor protein 3 (NLRP3) inflammasome is a multi-protein complex that controls the production of pro-inflammatory cytokines, IL-18 and IL-1β, through caspase-1 activation. These inflammatory cytokines play an important role in the development of multiple sclerosis (MS). The inflammasome NLRP3 gene variations and expression level have been suggested to affect the immune system activity. This case-control study was performed to determine the association of NLRP3 genetic variants and differential expression with MS...
September 28, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/30188011/hla-profile-of-the-donors-in-the-macedonian-bone-marrow-donor-registry
#8
Meri Kirijas, Sonja Genadieva Stavrik, Dejan Trajkov, Slavica Hristomanova Mitkovska, Aleksandar Senev, Olivija Efinska Mladenovska, Olgica Sibinovska, Aleksandar Petlichkovski
The importance of HLA alleles in the process of haematopoietic stem cell transplantation, especially the process of unrelated donor search, is enormous. Macedonian Bone Marrow Donor Registry was established in 2010 and has registered volunteer donors from different nationalities that live in the Republic of Macedonia. The aim of this study was to determine the HLA allele and haplotype frequencies of the volunteer donors from the Macedonian Bone Marrow Donor Registry and to compare this results with the Macedonians from a family study...
September 6, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/30117674/characterization-of-three-new-hla-class-i-alleles-in-chinese-individuals-hla-b-46-68-b-46-71-b-46-72
#9
Wei Wang, Nanying Chen, Lina Dong, Yanmin He, Sudan Tao, Wei Zhang, Ji He, Jiangtian Chen, Faming Zhu
Three new HLA class I alleles were described in the Chinese population. HLA-B*46:68,-B*46:71,-B*46:72 alleles differ from HLA-B*46:01:01 by a single nucleotide substitution at position 485C>T, 484A>G, 299T>A respectively.
August 17, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/30091527/nomenclature-for-factors-of-the-hla-system-update-may-2018
#10
Steven G E Marsh
No abstract text is available yet for this article.
August 9, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/30074682/nomenclature-for-factors-of-the-hla-system-update-june-2018
#11
Steven G E Marsh
No abstract text is available yet for this article.
August 3, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/30070777/nomenclature-for-factors-of-the-hla-system-update-april-2018
#12
Steven G E Marsh
No abstract text is available yet for this article.
August 2, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/29908012/allelic-and-haplotype-diversity-of-hla-a-hla-b-and-hla-drb1-gene-at-high-resolution-in-the-nanning-han-population
#13
YongFeng Pei, HuiNi Huang, HengCong Li, JieRun Chen, GuoGuang Wu
The distribution of human leucocyte antigen (HLA) allele and haplotype varied among different ethnic populations. In this study, we investigated the allele and haplotype frequencies of HLA-A, HLA-B and HLA-DRB1 loci in the Nanning Han population who live in Guangxi province of China. We identified 26 HLA-A, 56 HLA-B and 31 HLA-DRB1 alleles in 562 Nanning individuals of Han ethnic group by sequence-based typing method. Of these, the three most common alleles in HLA-A, HLA-B and HLA-DRB1 loci, respectively, were A*11:01 (32...
August 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/29869432/evaluation-of-ion-torrent-sequencing-technology-for-rapid-clinical-human-leucocyte-antigen-typing
#14
Sandra G Guerra, Winnie Chong, Colin J Brown, Cristina V Navarrete
The development of techniques to define the human leucocyte antigen (HLA) region has proven to be challenging due to its high level of polymorphism. Within a clinical laboratory, a technique for high-resolution HLA typing, which is rapid and cost effective is essential. NGS has provided a rapid, high-resolution HLA typing solution, which has reduced the number of HLA ambiguities seen with other typing methods. In this study, the One Lambda NXType NGS kit was tested on the Ion Torrent PGM platform. A total of 362 registry donors from four ethnic populations (Europeans, South Asians, Africans and Chinese) were NGS HLA typed across 9-loci (HLA-A, -B, -C, -DRB1,-DRB345 -DQB1 and -DPB1)...
August 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/29863307/association-of-cd14-and-macrophage-migration-inhibitory-factor-gene-polymorphisms-with-inflammatory-micrornas-expression-levels-in-ankylosing-spondylitis-and-polyarthralgia
#15
S K Vishwakarma, C Lakkireddy, G Sravani, B V S Sastry, N Raju, S I Ahmed, A A Khan, N Owaisi, A Jaisawal, M A Khan, A A Khan
This study aimed to investigate the genetic basis of ankylosing spondylitis (AS) and polyarthralgia (PA) conditions among Indian subjects through genotyping two immune regulatory genes CD14 (-159C>T) and MIF (-173G>C) and find their association with the expression levels of three circulating inflammatory miRNAs. This investigation may provide early genetic cause of these two forms of arthritis and more optimal biological targets to predict early therapeutic outcomes. A total of 140 patients (AS: 70 and PA: 70) and 156 controls were recruited from Indian population...
August 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/29799674/utility-of-next-generation-sequencing-methods-to-identify-the-novel-hla-alleles-in-potential-stem-cell-donors-from-chinese-marrow-donor-program
#16
Jun Qi, Tian-Ju Wang, Li-Ping Chen, Xiao-Fang Wang, Man-Ni Wang, Jun-Hua Wu
The human leucocyte antigen (HLA) is the most polymorphic region of the human genome. Compared with Sanger-sequencing-based typing (SBT) methods, next-generation sequencing (NGS) has significantly higher throughput and depth sequencing characteristics, having dramatic impacts on HLA typing in clinical settings. Here, we performed NGS technology with Ion Torrent S5 platform to evaluate the potential four novel HLA alleles detected in five donors from Chinese Marrow Donor Program (CMDP, Shaanxi Province) during routine Sanger SBT testing...
August 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/29797531/hla-g-regulatory-variants-and-haplotypes-with-susceptibility-to-recurrent-pregnancy-loss
#17
MULTICENTER STUDY
N Yazdani, M Shekari Khaniani, M Bastami, T Ghasemnejad, F Afkhami, S Mansoori Derakhshan
HLA-G is a nonclassical Class I major histocompatibility complex (MHC) gene. This gene has a limited protein alteration that is produced by alternative splicing and can be important in the preservation of pregnancy. Recent findings suggest that alteration in HLA-G gene expression can lead to pregnancy failure, such as recurrent pregnancy loss (RPL). As the promoter SNPs of the gene may impact the HLA-G expression levels, the study of these SNPs is very important. In this study, for the promoter region of HLA-G gene in the case group (100 women with a history of two or more repeated miscarriages) and the control group (100 women with at least two successful pregnancies), PCR reaction was performed...
August 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/29756405/duplicated-major-histocompatibility-complex-class-ii-genes-in-the-tongue-sole-cynoglossus-semilaevis
#18
C Li, J Jiang, Q Zhang, X Wang
The major histocompatibility complex (MHC) molecule plays an important role in the vertebrate immune system. However, we have a limited understanding of the MHC genomic structure in teleosts. Using gene cloning and family analysis, we isolate the MHC class II genes in the tongue sole (Cynoglossus semilaevis) and find that both class II A and class II B genes are duplicated (named Cyse-DAA and Cyse-DBA, Cyse-DAB and Cyse-DBB, respectively). The class II A genes consist of four exons with a highly conserved genomic structure, but each gene has unique and defining exon 2 and intron 2 sequences...
August 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/30063114/characterization-of-a-novel-allelic-variant-in-hla-b-46-01-lineage-hla-b-46-01-25-by-cloning-phasing-and-sequencing
#19
LiXin Li, Wei Tian, FaMing Zhu, WenYi Wang, Fan Wang
A new allelic variant in HLA-B*46:01 lineage, HLA-B*46:01:25, has been identified in a male individual of Mongol ethnicity residing in northern China. Following polymerase chain reaction-sequence-based typing (PCR-SBT), this novel variant was further confirmed by cloning, phasing and sequencing. HLA-B*46:01:25 differs from HLA-B*46:01:01 by a single synonymous T substitution at nucleotide position 137 (C - T) in exon 4, corresponding to codon 228 (ACC-ACT) of the mature HLA-B mRNA molecule.
July 31, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/30051604/hla-b-gene-somatic-insertion-deletion-mutations-in-patients-with-acute-myelogenous-leukaemia
#20
Nikola Königova, Ivana Skoumalova, Jana Onderkova, Zuzana Ambruzova, Tomas Szotkowski, Zdenek Koristek, Alena Maluskova, Ludek Raida, Frantisek Mrazek
Loss of heterozygosity is considered to be the most common type of tumour-specific somatic mutation of the human leucocyte antigens (HLA) genes in patients with haematological malignancies. Nevertheless, subtle DNA sequence changes, namely short insertions/deletions, may also abolish the expression of HLA molecules and interfere with routine HLA typing. Two male patients with acute myelogenous leukaemia (AML) were indicated for the search of a suitable donor for allogeneic haematopoietic stem cell transplantation (aHSCT)...
July 27, 2018: International Journal of Immunogenetics
journal
journal
40846
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"