journal
MENU ▼
Read by QxMD icon Read
search

Molecular Nutrition & Food Research

journal
https://www.readbyqxmd.com/read/28636182/effects-of-green-tea-on-lipid-metabolism-in-overweight-or-obese-people-a-meta-analysis-of-randomized-controlled-trials
#1
Yuan Fen, Dong Hui, Fang Ke, Gong Jing, Lu Fu Er
SCOPE: The effects of green tea on lipid metabolism were inconsistent. The objective of this meta-analysis was to evaluate the effects of green tea on lipid metabolism in overweight or obese people. METHODS AND RESULTS: We searched randomized controlled trials(RCTs) comparing green tea with a control on lipid metabolism on PUBMED and WEB OF SCIENCE (January 1990 to September 2016), COCHRANE and EMBASE (updated to October 2016), and the Chinese databases CNKI, WanFang and CBMD...
June 21, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28621836/-dietary-advanced-glycation-end-products-modify-gut-microbial-composition-and-partially-increase-colon-permeability-in-rats
#2
Wanting Qu, Xiaojin Yuan, Jinsong Zhao, Yingxiao Zhang, Jing Hu, Jiawei Wang, Juxiu Li
SCOPE: The adverse impacts of dietary advanced glycation end products (AGEs) on health are currently of interest. These compounds are inevitably formed during thermal food processing and make foods less digestible because of protein cross-linking. This study examined not only whether dietary AGEs alter cecal microbiota and their metabolites but also their effects on colon permeability. METHODS AND RESULTS: Sprague-Dawley rats were exposed to a high-AGEs diet (AGEs content was increased by heating food at 125°C/3 h) for 6, 12, or 18 weeks...
June 16, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28618113/the-mechanism-of-interactions-between-tea-polyphenols-and-porcine-pancreatic-alpha-amylase-analysis-by-inhibition-kinetics-fluorescence-quenching-differential-scanning-calorimetry-and-isothermal-titration-calorimetry
#3
Lijun Sun, Michael J Gidley, Fredrick J Warren
SCOPE: This study aims to use a combination of biochemical and biophysical methods to derive greater mechanistic understanding of the interactions between tea polyphenols and porcine pancreatic α-amylase (PPA). METHODS AND RESULTS: The interaction mechanism was studied through fluorescence quenching (FQ), differential scanning calorimetry (DSC) and isothermal titration calorimetry (ITC) and compared with inhibition kinetics. The results showed that a higher quenching effect of polyphenols corresponded to a stronger inhibitory activity against PPA...
June 15, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28608623/guar-gum-fiber-increases-suppressor-of-cytokine-signaling-1-expression-via-toll-like-receptor-2-and-dectin-1-pathways-regulating-inflammatory-response-in-small-intestinal-epithelial-cells
#4
Tran Van Hung, Takuya Suzuki
SCOPE: Direct regulation of intestinal inflammation by intact dietary fibers is still unclear. Here, the anti-inflammatory regulation by intact guar gum (GG) was investigated using mice and human intestinal Caco-2 cells. METHODS AND RESULTS: Administration of dextran sodium sulfate (DSS) increased myeloperoxidase activity and CXC motif chemokine ligand2 (an IL-8 homologue) expression in the small intestines of mice, while supplemental GG reduced these increases...
June 13, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28608449/resveratrol-suppresses-lipoprotein-associated-phospholipase-a2-expression-by-reducing-oxidative-stress-in-macrophages-and-animal-models
#5
Shengnan Sun, Mingjun Zhang, Qiangbing Yang, Ziying Shen, Jiahuan Chen, Biao Yu, He Wang, Jiali Qu, Daxin Pang, Wenzhi Ren, Hongsheng Ouyang, Xiaochun Tang
SCOPE: Resveratrol is a naturally occurring polyphenolic compound with known cardioprotective, anti-inflammatory and antioxidant properties. Lipoprotein-associated phospholipase A2 (Lp-PLA2 ) is associated with the risk of cardiovascular disease. Here, we investigated the effects of resveratrol on Lp-PLA2 expression in vitro and in vivo and explored the underlying mechanisms. METHODS AND RESULTS: Human monocytic cells (THP-1) were induced to differentiate into macrophages for an in vitro experimental model...
June 13, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28608394/a-discovery-driven-approach-to-elucidate-urinary-metabolome-changes-after-a-regular-and-moderate-consumption-of-beer-and-non-alcoholic-beer-in-subjects-at-high-cardiovascular-risk
#6
Paola Quifer-Rada, Gemma Chiva-Blanch, Olga Jáuregui, Ramon Estruch, Rosa M Lamuela-Raventos
SCOPE: The aim of this work was to study the urinary metabolomics changes of participants that consumed beer, non-alcoholic beer and gin. METHODS AND RESULTS: Thirty-three males at high cardiovascular risk between 55 and 75 years old participated in an open, randomized, crossover, controlled trial with three nutritional interventions consisting of beer, non-alcoholic beer and gin for four weeks. Diet and physical activity was monitored throughout the study and compliance was assessed by measurement of urinary isoxanthohumol...
June 13, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28605130/effect-of-cocoa-s-theobromine-on-intestinal-microbiota-of-rats
#7
Sandra Martín-Peláez, Mariona Camps-Bossacoma, Malen Massot-Cladera, Mar Rigo-Adrover, Àngels Franch, Francisco J Pérez-Cano, Margarida Castell
SCOPE: To establish the role of cocoa theobromine on gut microbiota composition and fermentation products after cocoa consumption in rats. METHODS AND RESULTS: Lewis rats were fed either a standard diet (RF diet), a diet containing 10% cocoa (CC diet) or a diet including 0.25% theobromine (TB diet) for 15 days. Gut microbiota (fluorescence in situ hybridization coupled to flow cytometry and metagenomics analysis), SCFA and IgA-coated bacteria were analyzed in fecal samples...
June 12, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28605127/serum-carotenoids-and-colorectal-cancer-risk-a-case-control-study-in-guangdong-china
#8
Jing Huang, Min-Shan Lu, Yu-Jing Fang, Ming Xu, Wu-Qing Huang, Zhi-Zhong Pan, Yu-Ming Chen, Cai-Xia Zhang
SCOPE: Previous epidemiological studies on the association between circulating carotenoids and the risk of colorectal cancer drew inconclusive conclusions. This study aimed to examine serum carotenoids in relation to colorectal cancer risk in a Chinese population. METHODS AND RESULTS: One case-control study beginning from July 2010, consecutively recruited 538 eligible colorectal cancer cases and 564 age (5-year interval) and sex frequency-matched controls. Serum levels of α-carotene, β-carotene, β-cryptoxanthin, lycopene and lutein/ zeaxanthin were detected by HPLC...
June 12, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28605125/isoflavones-and-their-metabolites-influence-the-milk-component-synthesis-ability-of-mammary-epithelial-cells-through-prolactin-stat5-signaling
#9
Yusaku Tsugami, Kota Matsunaga, Takahiro Suzuki, Takanori Nishimura, Ken Kobayashi
SCOPE: Isoflavones are a class of polyphonic compounds present in legumes and are called phytoestrogens because of their estrogen-like activity. Estrogen influences the behavior of mammary epithelial cells (MECs) during pregnancy and lactation. In this study, we investigated the direct influences of isoflavones and their metabolites in milk production ability of MECs. METHODS AND RESULTS: Mouse MECs were cultured with prolactin and dexamethasone (glucocorticoid analog) to induce milk production ability...
June 12, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28594130/maintaining-good-mirnas-in-the-body-keeps-the-doctor-away-perspectives-on-the-relationship-between-food-derived-natural-products-and-micrornas-in-relation-to-exosomes-extracellular-vesicles
#10
REVIEW
Kurataka Otsuka, Yusuke Yamamoto, Ryosuke Matsuoka, Takahiro Ochiya
During the last decade, it has been uncovered that microRNAs (miRNAs), a class of small non-coding RNAs, are related to many diseases including cancers. With an increase in reports describing the dysregulation of miRNAs in various tumor types, it has become abundantly clear that miRNAs play significant roles in the formation and progression of cancers. Intriguingly, miRNAs are present in body fluids because they are packed in exosomes/extracellular vesicles and released from all types of cells. The miRNAs in the fluids are measured in a relatively simple way and the profile of miRNAs is likely to be an indicator of health condition...
June 8, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28594107/mirnas-in-nutrition-obesity-and-cancer-the-biology-of-mirnas-in-metabolic-disorders-and-its-relationship-with-cancer-development
#11
Verónica Del Carmen Martínez-Jiménez, Alejandro Méndez-Mancilla, Diana Patricia Portales-Pérez
SCOPE: The scope of this review is to explain how metabolic disorders originated by a deficient nutrition can develop into a neoplasic process by the alteration of epigenetic mechanisms like miRNAs. Obesity is a proinflammatory state with a wide impact on health around the world that is associated with neoplastic diseases. Epigenetic mechanisms have a central role in the obesogenic environment, which participates on the development of comorbidities such as cancer. METHODS AND RESULTS: We made an exhaustive review of the most recent reports about metabolic disorders with nutrition and their relationship with miRNAs, and their risk of developing into oncogenic processes...
June 8, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28589636/25-hydroxyvitamin-d3-and-its-c-3-epimer-are-elevated-in-the-skin-and-serum-of-skh-1-mice-supplemented-with-dietary-vitamin-d3
#12
Matthew D Teegarden, Amanda R Campbell, Jessica L Cooperstone, Kathleen L Tober, Steven J Schwartz, Tatiana M Oberyszyn
SCOPE: UV exposure is a risk factor for keratinocyte carcinoma (KC) while critical for endogenous vitamin D production. We investigated dietary modulation of skin and serum 25-hydroxyvitamin D3 (25OHD3 ) and its C-3 epimer (C3epi) in a mouse model of KC. C3epi is an under-investigated metabolite of vitamin D with respect to its biological implications. METHODS AND RESULTS: Male and female Skh-1 mice were supplemented with 25, 150 or 1000 IU/kg diet vitamin D3 for 25 weeks, with some exposed to UV light...
June 7, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28586175/adaptation-of-gut-microbiome-to-different-dietary-non-starch-polysaccharide-fractions-in-a-porcine-model
#13
Gang Tian, Xiying Wu, Daiwen Chen, Bing Yu, Jun He
SCOPE: Dietary fibers, consisting of non-starch polysaccharides (NSPs) were found to modulate the gut microbiota. However, little is known about the role of a separated fiber fraction. Here, we describe a response in gut microbiome to different fiber fractions using a porcine model. METHODS AND RESULTS: Ileal and cecal digesta were collected from pigs fed with fiber-free diet (FFD) or diet containing 5% cellulose (CEL), xylan (XYL) or β-glucan (GLU). We observed an elevated 16S rRNA gene copies in ileum and cecum digesta after NSP ingestion...
June 6, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28586173/xanthophyll-esters-are-found-in-human-colostrum
#14
José J Ríos, Ana Augusta Odorissi Xavier, Elena Díaz-Salido, Isabel Arenilla-Vélez, Manuel Jarén-Galán, Juan Garrido-Fernández, Josefa Aguayo-Maldonado, Antonio Pérez-Gálvez
SCOPE: Carotenoids in human milk are associated with other lipid counterparts in several metabolic processes. One interesting association that has not been demonstrated to date is the presence of xanthophyll esters. Colostrum and mature milk samples were analysed to determine the occurrence of xanthophyll esters and identify the compounds. Thus, the association of the amounts of these compounds with lactation and whether they are significant contributors to the carotenoid profile of human milk was assessed...
June 6, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28586170/pru-p-3-epitope-based-sublingual-immunotherapy-in-a-murine-model-for-the-treatment-of-peach-allergy
#15
Maria J Rodriguez, Ainhoa Mascaraque, Francisco J Ramos-Soriano, Maria J Torres, James R Perkins, Francisca Gomez, Maria Garrido, Nuria Cubells, David Andreu, Araceli Diaz-Perales, Javier Rojo, Cristobalina Mayorga
SCOPE: Food-specific immunotherapy (SIT) is a promising treatment for LTP-syndrome. We propose a novel sublingual-SIT (SLIT) that combines a Pru p 3 T-cell peptide and an oligodeoxyribonucleotide (ODN) with CpG motifs (ODN-CpG) as adjuvants to induce a specific Th1/Treg response. METHODS AND RESULTS: LTP-peach allergic mice were treated sublingually with a combination of a CpG sequence and mono- or tetravalent systems including a Pru p 3 peptide, D1 (Prup3) or D4 (Prup3)...
June 6, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28586169/metabolomic-based-identification-of-clusters-that-reflect-dietary-patterns
#16
Helena Gibbons, Eibhlin Carr, Breige A McNulty, Anne P Nugent, Janette Walton, Albert Flynn, Michael J Gibney, Lorraine Brennan
SCOPE: Classification of subjects into dietary patterns generally relies on self-reporting dietary data which are prone to error. The aim of the present study was to develop a model for objective classification of people into dietary patterns based on metabolomic data. METHODS AND RESULTS: Dietary and urinary metabolomic data from the National Adult Nutrition Survey (NANS) was used in the analysis (n = 567). Two-step cluster analysis was applied to the urinary data to identify clusters...
June 6, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28586165/3-3-diindolylmethane-suppresses-high-fat-diet-induced-obesity-through-inhibiting-adipogenesis-of-pre-adipocytes-by-targeting-usp2-activity
#17
Hee Yang, Sang Gwon Seo, Seung Ho Shin, Soyun Min, Min Jeong Kang, Ra Yoo, Jeong Yeon Kwon, Shuhua Yue, Kee Hong Kim, Ji-Xin Cheng, Jong Rhan Kim, Jun Suk Park, Jong Hun Kim, Jung Han Yoon Park, Hyong Joo Lee, Ki Won Lee
SCOPE: Indole-3-carbinol (I3C), a derivative abundant in cruciferous vegetables such as cabbage, is well known for its various health benefits such as chemo-preventive and anti-obesity effects. I3C is easily metabolized to 3,3'-diindolylmethane (DIM), a more stable form, in acidic conditions of the stomach. However, the anti-obesity effect of DIM has not been investigated clearly. We sought to investigate the effect of DIM on diet-induced obesity and to elucidate its underlying mechanisms...
June 6, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28586162/chain-length-dependent-effects-of-inulin-type-fructan-dietary-fiber-on-human-systemic-immune-responses-against-hepatitis-b
#18
Leonie M Vogt, Marlies E Elderman, Theo Borghuis, Bart J de Haan, Marijke M Faas, Paul de Vos
SCOPE: In vivo studies demonstrating that only specific dietary-fibers contribute to immunity are still inconclusive, as measuring immune effects in healthy humans remains difficult. We applied a relatively inefficacious vaccination-challenge to study chain length-dependent effects of inulin-type fructan (ITF) dietary fibers on human immunity. METHODS AND RESULTS: ITFs with two different 'degree of polymerization-' (DP)-profiles were tested in vitro for effects on PBMC-cytokines and TLR2 activation...
June 6, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28568316/influence-of-diabetes-on-plasma-pharmacokinetics-and-brain-bioavailability-of-grape-polyphenols-and-their-phase-ii-metabolites-in-the-zucker-diabetic-fatty-rat
#19
Tzu-Ying Chen, Mario G Ferruzzi, Qing-Li Wu, James E Simon, Stephen T Talcott, Jun Wang, Lap Ho, George Todd, Bruce Cooper, Giulio M Pasinetti, Elsa M Janle
SCOPE: The effect of diabetes on the pharmacokinetics, bioavailability and brain distribution of grape polyphenols and select metabolites was studied in the Zucker diabetic fatty (ZDF) rat model. METHODS AND RESULTS: (ZDF) rats and their lean controls (LN) were dosed with a Standardized Grape Polyphenol (SGP) Mixture consisting of grape seed extract, Concord grape juice and resveratrol (RES) by oral gavage for 10 days. An 8 hour pharmacokinetic study was performed...
June 1, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28556578/fasting-serum-hippuric-acid-is-elevated-after-bilberry-vaccinium-myrtillus-consumption-and-associates-with-improvement-of-fasting-glucose-levels-and-insulin-secretion-in-persons-at-high-risk-of-developing-type-2-diabetes
#20
Vanessa Df de Mello, Maria A Lankinen, Jaana Lindström, Riitta Puupponen-Pimiä, David E Laaksonen, Jussi Pihlajamäki, Marko Lehtonen, Matti Uusitupa, Jaakko Tuomilehto, Marjukka Kolehmainen, Riitta Törrönen, Kati Hanhineva
SCOPE: Urinary hippuric acid has been proposed as a biomarker for fruit, vegetable and polyphenol consumption. We assessed how serum hippuric acid changes after a bilberry-enriched diet (BB; high anthocyanin intake) and another berry diet including strawberries, raspberries and cloudberries (SRC; lower anthocyanin intake) and how these changes associate with insulin and glucose metabolism. METHODS AND RESULTS: Hippuric acid was measured with LC-QTOF-MS metabolite profiling analysis from fasting serum samples at baseline and after an 8-week intervention in 47 individuals with features of the metabolic syndrome who were randomized to either a BB diet (n = 15), a SRC diet (n = 20) or a control diet (n = 12)...
May 29, 2017: Molecular Nutrition & Food Research
journal
journal
40833
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"