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International Wound Journal

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https://www.readbyqxmd.com/read/28799268/reply-to-effectiveness-of-a-multi-layer-foam-dressing-in-preventing-sacral-pressure-ulcers-in-the-early-acute-care-of-patients-with-a-traumatic-spinal-cord-injury-comparison-with-the-use-of-a-gel-mattress-by-gefen-and-santamaria
#1
LETTER
Andréane Richard-Denis, Cynthia Thompson, Jean-Marc Mac-Thiong
No abstract text is available yet for this article.
August 10, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28799228/chitin-and-chitosan-biopolymers-for-wound-management
#2
Rita Singh, Kirti Shitiz, Antaryami Singh
Chitin and chitosan are biopolymers with excellent bioactive properties, such as biodegradability, non-toxicity, biocompatibility, haemostatic activity and antimicrobial activity. A wide variety of biomedical applications for chitin and chitin derivatives have been reported, including wound-healing applications. They are reported to promote rapid dermal regeneration and accelerate wound healing. A number of dressing materials based on chitin and chitosan have been developed for the treatment of wounds. Chitin and chitosan with beneficial intrinsic properties and high potential for wound healing are attractive biopolymers for wound management...
August 10, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28799192/wood-s-lamp-for-vitiligo-disease-stability-and-early-recognition-of-initiative-pigmentation-after-epidermal-grafting
#3
Yen-Jen Wang, Chang-Cheng Chang, Kun-Lin Cheng
The prerequisite for a successful vitiligo epidermal grafting surgery is the stable status of the disease. We used Wood's lamp to assess vitiligo activity to determine the disease stability, surgical grafting timing and the early recognition of re-pigmentation after grafting. Amelanotic lesions with sharply demarcated borders are typically stable and are good candidates for grafting. The re-pigmentation was first recognised under Wood's lamp as hypochromic islands, which progressed to normally pigmented islands...
August 10, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28782223/how-and-why-patients-self-treat-chronic-wounds
#4
Suzanne Kapp, Nick Santamaria
The aim of this study was to investigate how people self-treat chronic wounds, why they self-treat and the assistance and support that they receive. The increasing emphasis on self-management of chronic conditions, the potential benefits of self-treatment to the health care consumer and competing demands on health care funding are good reasons to investigate self-treatment of chronic wounds as we have little data on this group of individuals. A survey study was conducted in Australia. A non-random sample of 100 participants was recruited...
August 6, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28782201/cross-cultural-adaptation-reproducibility-and-validation-of-the-italian-version-of-the-patient-and-observer-scar-assessment-scale-posas
#5
Stefano Vercelli, Giorgio Ferriero, Elisabetta Bravini, Valeria Stissi, Matteo Ciceri, Sara Rossetti, Sara Bianchi, Francesco Sartorio
The Patient and Observer Scar Assessment Scale (POSAS) is one of the most robust instruments to assess scar quality, but there is no Italian version, and no other competing instruments are available in Italian. The aim of this study was to translate and validate an Italian version of POSAS (POSAS-I). POSASv2.0 was culturally adapted in accordance with international standards. The psychometric assessment included acceptability/feasibility, internal consistency, reproducibility, construct validity and sensitivity to change...
August 6, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28771993/a-pegylated-fibrin-hydrogel-based-antimicrobial-wound-dressing-controls-infection-without-impeding-wound-healing
#6
Joel Gil, Shanmugasundaram Natesan, Jie Li, Jose Valdes, Andrew Harding, Michael Solis, Stephen C Davis, Robert J Christy
Combat injuries are associated with a high incidence of infection, and there is a continuing need for improved approaches to control infection and promote wound healing. Due to the possible local and systemic adverse effects of standard 1% cream formulation (Silvadene), we had previously developed a polyethylene glycol (PEGylated) fibrin hydrogel (FPEG)-based wound dressing for the controlled delivery of silver sulfadiazine (SSD) entrapped in chitosan microspheres (CSM). In this study, we have evaluated the antimicrobial and wound healing efficacy of SSD-CSM-FPEG using a full-thickness porcine wound infected with Pseudomonas aeruginosa...
August 2, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28770561/evaluation-of-a-muscle-pump-activating-device-for-non-healing-venous-leg-ulcers
#7
Connie Harris, Rochelle Duong, Gwen Vanderheyden, Beth Byrnes, Renee Cattryse, Ava Orr, David Keast
This evaluation involves an innovative muscle pump-activating device (geko™) as an adjunctive therapy with best practices for non-healing venous leg ulcers (VLUs). Stimulating the common peroneal nerve (at the fibular head), the geko™ device creates a response that acts as foot and calf muscle pumps, increasing venous, arterial and microcirculatory flow. The aim was to evaluate and determine if the geko™ is effective in this population and if it should be added to the medical supply formulary. In all, 12 patients with 18 recalcitrant VLUs (defined as less than 30% reduction in wound size in 30 days with best practices) in two community settings in Ontario consented to the evaluation and were treated with the geko™ for up to 20 weeks...
August 2, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28745010/the-detrimental-impact-of-extracellular-bacterial-proteases-on-wound-healing
#8
Sharon Lindsay, Angela Oates, Katie Bourdillon
In addition to clinical signs of infection (e.g. inflammation, purulence and pain), a microbial count of ≥10(5) colony-forming units/g has historically been used to define wound infection. However, it is increasingly recognised that, rather than a high bioburden level alone being detrimental to wound healing, it is the virulence of the invading microorganism and the host's immune status that can affect clinical outcomes. Bacteria, such as Pseudomonas aeruginosa, Staphylococcus aureus and Staphylococcus epidermidis, have developed a range of virulence factors to help them overcome host defences and proliferate within the underlying soft tissue...
July 25, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28745005/can-a-morel-lavall%C3%A3-e-lesion-be-misdiagnosed-as-a-mass-like-lesion
#9
Yoon Jae Lee, Jun Hyeok Kim, Ji Young Kim, Hyun Ho Han
The Morel-Lavallée lesion (MLL) is a post-traumatic closed soft tissue degloving injury. Common complaints of MLL patients are a haematoma or fluid collection on the trunk or the lower extremity. However, the authors introduce unique cases of MLL that present an atypical appearance. The fluid collection was not apparent, and the capsule formation was not detected on preoperative image study. The main complaint of patients was the uncomfortable mass-like lesion that was regarded as a simple benign lump. The purpose of this case study is to introduce the atypical cases of MLL and to help other physicians make accurate diagnosis based on trial and error of our cases...
July 25, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28744988/adherence-to-evidence-based-pressure-injury-prevention-guidelines-in-routine-clinical-practice-a-longitudinal-study
#10
Wendy Chaboyer, Tracey Bucknall, Brigid Gillespie, Lukman Thalib, Elizabeth McInnes, Julie Considine, Edel Murray, Paula Duffy, Michelle Tuck, Emma Harbeck
The aim of this longitudinal study was to describe adherence to evidence-based pressure injury (PI) prevention guidelines in routine clinical practice in Australian hospitals. Data were analysed from four control sites of a larger-cluster randomised trial of a PI intervention. The sample of 799 included 220 (27·5%) Not at risk, 344 (43·1%) At risk and 110 (13·8%) At high risk patients. A total of 84 (10·5%) patients developed a PI during the study: 20 (9·0% of 220) in the Not at risk group, 45 (13·1% of 344) in the At risk group, 15 (13·6% of 110) in the At high risk group and 4 (3·2% of 125) patients who did not have a risk assessment completed...
July 25, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28744967/compression-therapy%C3%A2-%C3%A2-cross-sectional-observational-survey-about-knowledge-and-practical-treatment-of-specialised-and-non-specialised-nurses-and-therapists
#11
Kristina Heyer, Kerstin Protz, Matthias Augustin
Knowledge about methods and materials and their correct usage is the basis for compression therapy. This study compares knowledge and practical skills of participants with further training with those who had no training. This comparison provides information on whether further qualifications have an impact on knowledge and practical skills. In seminars for compression therapy, data on specific and non-specific expertise were acquired. A practical test determined the participants' skills for creating a compression bandage in a pressure value range of 50-60 mmHg...
July 25, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28736990/comparing-the-reported-burn-conditions-for-different-severity-burns-in-porcine-models-a-systematic-review
#12
Christine J Andrews, Leila Cuttle
There are many porcine burn models that create burns using different materials (e.g. metal, water) and different burn conditions (e.g. temperature and duration of exposure). This review aims to determine whether a pooled analysis of these studies can provide insight into the burn materials and conditions required to create burns of a specific severity. A systematic review of 42 porcine burn studies describing the depth of burn injury with histological evaluation is presented. Inclusion criteria included thermal burns, burns created with a novel method or material, histological evaluation within 7 days post-burn and method for depth of injury assessment specified...
July 23, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28736974/topical-sevoflurane-for-chronic-venous-ulcers-infected-by-multi-drug-resistant-organisms
#13
Adrián Imbernón-Moya, Francisco Javier Ortiz-de Frutos, Mónica Sanjuan-Alvarez, Isabel Portero-Sanchez, Raúl Merinero-Palomares, Victoria Alcazar
Several anaesthetic drugs have demonstrated antibacterial properties in vitro. Anaesthetics can primarily affect the cell wall of both susceptible and multi-resistant bacteria. They may also have a synergistic effect with conventional antibiotics through an unknown mechanism. We present three cases of a chronic venous ulcer infected by multi-resistant bacteria refractory to conventional systemic antibiotics, including Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA). Treatment with topical sevoflurane was performed for 1 month without systemic antibiotics...
July 23, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28736958/intraoperative-indocyanine-green-fluorescent-angiography-assisted-modified-superior-gluteal-artery-perforator-flap-for-reconstruction-of-sacral-pressure-sores
#14
Chun-Kai Chang, Chien-Ju Wu, Chun-Yu Chen, Chi-Yu Wang, Tzi-Shiang Chu, Kuo-Feng Hsu, Han-Ting Chiu, Hung-Hui Liu, Chang-Yi Chou, Chih-Hsin Wang, Chin-Ta Lin, Niann-Tzyy Dai, Yuan-Sheng Tzeng
Pressure sores are often observed in patients who are bedridden. They can be a severe problem not only for patients and their caregivers but also for plastic surgeons. Here, we describe a new method of superior gluteal artery perforator flap harvesting and anchoring with the assistance of intraoperative indocyanine green fluorescent angiography. In this report, we describe the procedure and outcomes for 19 patients with grades III and IV sacral pressure sores who underwent the operation between September 2015 and November 2016...
July 23, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28730726/changes-in-the-extracellular-matrix-surrounding-human-chronic-wounds-revealed-by-2-photon-imaging
#15
Jessica E S Sutcliffe, Christopher Thrasivoulou, Thomas E Serena, Leigh Madden, Toby Richards, Anthony R J Phillips, David L Becker
Chronic wounds are a growing problem worldwide with no effective therapeutic treatments available. Our objective was to understand the composition of the dermal tissue surrounding venous leg ulcers and diabetic foot ulcers (DFU). We used novel 2-photon imaging techniques alongside classical histology to examine biopsies from the edges of two common types of chronic wound, venous leg ulcers and DFU. Compared to normal intact skin, we found that collagen levels are significantly reduced throughout the dermis of venous leg ulcer biopsies and DFU, with a reduction in both fibril thickness and abundance...
July 20, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28722354/risk-factors-for-amputation-in-patients-with-diabetic-foot-infection-a-prospective-study
#16
Serhat Uysal, Bilgin Arda, Meltem I Taşbakan, Şevki Çetinkalp, Ilgın Y Şimşir, Anıl M Öztürk, Ayşe Uysal, İlgen Ertam
There is a variety of diagnostic and therapeutic algorithms for diabetic foot infections (DFIs). Some of them are too difficult to be applied in routine clinical approach. In the routine clinical approach, it is necessary to find new risk factors and end up with a quick and easy assessment of DFIs. In this study, we aimed to evaluate the independent risk factors for osteomyelitis, amputation and major amputation in patients with DFI using standard scoring procedures. We prospectively studied 379 patients with DFI...
July 19, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28707450/a-simple-concept-for-covering-pressure-sores-wound-edge-based-propeller-perforator-flap
#17
Osman Kelahmetoglu, Koenraad Van Landuyt, Caglayan Yagmur, Casper E Sommeling, Musa K Keles, Volkan Tayfur, Tekin Simsek, Yener Demirtas, Ethem Guneren
We present a new surgical modification to allow propeller perforator flaps to cover pressure sores at various locations. We used a propeller perforator flap concept based on the detection of newly formed perforator vessels located 1 cm from the wound margin and stimulated by the chronic inflammation process. Between January 2009 and January 2017, 33 wound edge-based propeller perforator flaps were used to cover pressure sores at various locations in 28 patients. In four cases more than one flap was used on the same patient...
July 13, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28707412/differences-in-the-daily-activity-of-patients-with-diabetic-foot-ulcers-compared-to-controls-in-their-free-living-environments
#18
Helen Sheahan, Kimberley Canning, Nishka Refausse, Ewan M Kinnear, Greg Jorgensen, James R Walsh, Peter A Lazzarini
The aims of our study were to investigate multiple daily activity outcomes in patients with diabetic foot ulcers (DFU) compared to diabetic peripheral neuropathy (DPN) and diabetes (DM) controls in their free-living environments. We examined daily activity outcomes of 30 patients with DFU, 23 DPN and 20 DM. All patients wore a validated multi-sensor device for > 5 days (>22 hours per day) to measure their daily activity outcomes: steps, energy expenditure (kJ), average metabolic equivalent tasks (METs), physical activity (>3·0 METs) duration and energy expenditure, lying duration, sleep duration and sleep quality...
July 13, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28664657/refractory-venous-leg-ulcers-observational-evaluation-of-innovative-new-technology
#19
Connie Harris, Amanda Loney, Jillian Brooke, Amanda Charlebois, Lucy Coppola, Sowmil Mehta, Norman Flett
This observational case series reports the evaluation of a novel neuromuscular electrical stimulation device (geko™) that stimulates the common peroneal nerve at the fibular head as an adjunctive therapy in patients with non-healing venous leg ulcers. The aim was to evaluate and determine if the geko™ device was effective in this population and should be added to the medical supply formulary. Patients whose wounds had failed to heal within 24 weeks of standard therapy were identified in two community settings in Ontario...
June 30, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28661069/the-posterior-thigh-flap-for-defect-coverage-of-ischial-pressure-sores%C3%A2-%C3%A2-a-critical-single-centre-analysis
#20
Gabriel Djedovic, Evi M Morandi, Julia Metzler, Anna Wirthmann, Johannes Matiasek, Thomas Bauer, Ulrich M Rieger
The development of pressure sores is still not only an enormous economical but also a medical burden. Especially in the ischial region, the local defect coverage remains demanding as it is the main weight-bearing area in wheelchair-mobilised patients and is prone to high mobility. The purpose of our study was to report our long-time experience with the reconstruction of ischial pressure ulcers with the medially based posterior thigh flap. A retrospective analysis of all primary pressure sores grade III-IV in the ischial area, which were covered with a medially based posterior thigh flap between January 2008 and December 2014, at our department was conducted...
June 29, 2017: International Wound Journal
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