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International Wound Journal

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https://www.readbyqxmd.com/read/28730726/changes-in-the-extracellular-matrix-surrounding-human-chronic-wounds-revealed-by-2-photon-imaging
#1
Jessica E S Sutcliffe, Christopher Thrasivoulou, Thomas E Serena, Leigh Madden, Toby Richards, Anthony R J Phillips, David L Becker
Chronic wounds are a growing problem worldwide with no effective therapeutic treatments available. Our objective was to understand the composition of the dermal tissue surrounding venous leg ulcers and diabetic foot ulcers (DFU). We used novel 2-photon imaging techniques alongside classical histology to examine biopsies from the edges of two common types of chronic wound, venous leg ulcers and DFU. Compared to normal intact skin, we found that collagen levels are significantly reduced throughout the dermis of venous leg ulcer biopsies and DFU, with a reduction in both fibril thickness and abundance...
July 20, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28722354/risk-factors-for-amputation-in-patients-with-diabetic-foot-infection-a-prospective-study
#2
Serhat Uysal, Bilgin Arda, Meltem I Taşbakan, Şevki Çetinkalp, Ilgın Y Şimşir, Anıl M Öztürk, Ayşe Uysal, İlgen Ertam
There is a variety of diagnostic and therapeutic algorithms for diabetic foot infections (DFIs). Some of them are too difficult to be applied in routine clinical approach. In the routine clinical approach, it is necessary to find new risk factors and end up with a quick and easy assessment of DFIs. In this study, we aimed to evaluate the independent risk factors for osteomyelitis, amputation and major amputation in patients with DFI using standard scoring procedures. We prospectively studied 379 patients with DFI...
July 19, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28707450/a-simple-concept-for-covering-pressure-sores-wound-edge-based-propeller-perforator-flap
#3
Osman Kelahmetoglu, Koenraad Van Landuyt, Caglayan Yagmur, Casper E Sommeling, Musa K Keles, Volkan Tayfur, Tekin Simsek, Yener Demirtas, Ethem Guneren
We present a new surgical modification to allow propeller perforator flaps to cover pressure sores at various locations. We used a propeller perforator flap concept based on the detection of newly formed perforator vessels located 1 cm from the wound margin and stimulated by the chronic inflammation process. Between January 2009 and January 2017, 33 wound edge-based propeller perforator flaps were used to cover pressure sores at various locations in 28 patients. In four cases more than one flap was used on the same patient...
July 13, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28707412/differences-in-the-daily-activity-of-patients-with-diabetic-foot-ulcers-compared-to-controls-in-their-free-living-environments
#4
Helen Sheahan, Kimberley Canning, Nishka Refausse, Ewan M Kinnear, Greg Jorgensen, James R Walsh, Peter A Lazzarini
The aims of our study were to investigate multiple daily activity outcomes in patients with diabetic foot ulcers (DFU) compared to diabetic peripheral neuropathy (DPN) and diabetes (DM) controls in their free-living environments. We examined daily activity outcomes of 30 patients with DFU, 23 DPN and 20 DM. All patients wore a validated multi-sensor device for > 5 days (>22 hours per day) to measure their daily activity outcomes: steps, energy expenditure (kJ), average metabolic equivalent tasks (METs), physical activity (>3·0 METs) duration and energy expenditure, lying duration, sleep duration and sleep quality...
July 13, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28664657/refractory-venous-leg-ulcers-observational-evaluation-of-innovative-new-technology
#5
Connie Harris, Amanda Loney, Jillian Brooke, Amanda Charlebois, Lucy Coppola, Sowmil Mehta, Norman Flett
This observational case series reports the evaluation of a novel neuromuscular electrical stimulation device (geko™) that stimulates the common peroneal nerve at the fibular head as an adjunctive therapy in patients with non-healing venous leg ulcers. The aim was to evaluate and determine if the geko™ device was effective in this population and should be added to the medical supply formulary. Patients whose wounds had failed to heal within 24 weeks of standard therapy were identified in two community settings in Ontario...
June 30, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28661069/the-posterior-thigh-flap-for-defect-coverage-of-ischial-pressure-sores%C3%A2-%C3%A2-a-critical-single-centre-analysis
#6
Gabriel Djedovic, Evi M Morandi, Julia Metzler, Anna Wirthmann, Johannes Matiasek, Thomas Bauer, Ulrich M Rieger
The development of pressure sores is still not only an enormous economical but also a medical burden. Especially in the ischial region, the local defect coverage remains demanding as it is the main weight-bearing area in wheelchair-mobilised patients and is prone to high mobility. The purpose of our study was to report our long-time experience with the reconstruction of ischial pressure ulcers with the medially based posterior thigh flap. A retrospective analysis of all primary pressure sores grade III-IV in the ischial area, which were covered with a medially based posterior thigh flap between January 2008 and December 2014, at our department was conducted...
June 29, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28643421/re-epidermal-skin-grafting-in-vitiligo-a-pilot-study
#7
LETTER
Kun-Lin Cheng, Chang-Cheng Chang, Yen-Jen Wang
No abstract text is available yet for this article.
June 23, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28643380/microscopy-visualisation-confirms-multi-species-biofilms-are-ubiquitous-in-diabetic-foot-ulcers
#8
Khalid Johani, Matthew Malone, Slade Jensen, Iain Gosbell, Hugh Dickson, Honhua Hu, Karen Vickery
Increasing evidence within the literature has identified the presence of biofilms in chronic wounds and proposed that they contribute to delayed wound healing. This research aimed to investigate the presence of biofilm in diabetic foot ulcers (DFUs) using microscopy and molecular approaches and define if these are predominantly mono- or multi-species. Secondary objectives were to correlate wound observations against microscopy results in ascertaining if clinical cues are useful in detecting wound biofilm. DFU tissue specimens were obtained from 65 subjects...
June 23, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28635188/the-financial-and-quality-of-life-cost-to-patients-living-with-a-chronic-wound-in-the-community
#9
Suzanne Kapp, Nick Santamaria
Chronic wounds are associated with financial and personal costs. The system level expense associated with chronic wounds has been established, however, the out-of-pocket cost incurred by individuals who self-fund has not been the focus of extensive investigation. Recently, there has been renewed interest in evaluating quality of life, in line with the shift to patient enablement and self-care in chronic disease management. The objectives of this research were to describe the out-of-pocket wound treatment costs and the quality of life of people who have chronic wounds...
June 20, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28635042/palpation-for-pressure-ulcers-examining-the-bony-prominence-and-physical-properties-of-the-wound
#10
LETTER
Yoshiko Takahashi, Fumihiro Mizokami, Zenzo Isogai
No abstract text is available yet for this article.
June 20, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28612500/using-image-j-to-document-healing-in-ulcers-of-the-foot-in-diabetes
#11
William J Jeffcoate, Alison J Musgrove, Nadina B Lincoln
The aim of the study was to assess the reliability of measuring the cross-sectional area of diabetic foot ulcers using Image J software. The inter- and intra-rater reliability of ulcer area measures were assessed using digital images of acetate tracings of ulcers of the foot affecting 31 participants in an off-loading randomised trial. Observations were made independently by five specialist podiatrists, one of whom was experienced in the use of Image J software and educated the other four in a single session...
June 13, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28612454/assessing-and-comparing-the-quality-of-wound-centres-a-literature-review-and-benchmarking-pilot
#12
Lotte Pruim, Anke Wind, Wim H van Harten
Multidisciplinary wound centres are currently facing an increase in both the incidence of wounds and the complexity of care. This has resulted in rising costs and increased interest in the effectiveness of treatments. Little evidence is available regarding optimal wound centre organisation and effectiveness; therefore, measuring the quality of wound centres has become more important. This study aims to assess the evidence concerning quality by describing the state of the art of wound centres and organisational effectiveness by developing indicators of quality and by assessing their suitability in a pilot study...
June 13, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28580759/a-quality-control-circle-process-to-improve-implementation-effect-of-prevention-measures-for-high-risk-patients
#13
Haixia Feng, Guohong Li, Cuirong Xu, Changping Ju, Peiheng Suo
The aim of the study was to analyse the influence of prevention measures on pressure injuries for high-risk patients and to establish the most appropriate methods of implementation. Nurses assessed patients using a checklist and factors influencing the prevention of a pressure injury determined by brain storming. A specific series of measures was drawn up and an estimate of risk of pressure injury determined using the Braden Scale, analysis of nursing documents, implementation of prevention measures for pressure sores and awareness of the system both before and after carrying out a quality control circle (QCC) process...
June 4, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28547841/successful-treatment-of-smallpox-scars-by-using-radiofrequency-device-with-single-microneedle
#14
LETTER
Kwang Ho Yoo, Ga Ram Ahn, Joon Seok, Yu-Jin Jang, Beom Joon Kim
No abstract text is available yet for this article.
May 26, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28547752/development-and-psychometric-validation-of-pukat-2%C3%A2-0-a-knowledge-assessment-tool-for-pressure-ulcer-prevention
#15
Bénédicte Manderlier, Nele Van Damme, Katrien Vanderwee, Sofie Verhaeghe, Ann Van Hecke, Dimitri Beeckman
The aim of this study was to develop a tool to measure the knowledge of nurses on pressure ulcer prevention. PUKAT 2·0 is a revised and updated version of the Pressure Ulcer Knowledge Assessment Tool (PUKAT) developed in 2010 at Ghent University, Belgium. The updated version was developed using state-of-the-art techniques to establish evidence concerning validity and reliability. Face and content validity were determined through a Delphi procedure including both experts from the European Pressure Ulcer Advisory Panel (EPUAP) and the National Pressure Ulcer Advisory Panel (NPUAP) (n = 15)...
May 26, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28547751/education-and-process-change-to-improve-skin-health-in%C3%A2-a%C3%A2-residential-aged-care-facility
#16
Kay Price, Kate J Kennedy, Tabatha L Rando, Anthony R Dyer, Jo Boylan
We report on an intervention and evaluation in relation to changes in staff knowledge, time spent on healing and wound prevention and proportion of wounds in the facilities before and after. A rapid review of recent peer-reviewed literature (2006-2016) found 14 education-based intervention articles and provided the background and context for this intervention. A cohort of 164 nurses and personal care workers and 261 residents at two aged care-approved facilities contributed to this intervention on the effect of education, mentoring and practice change on staff knowledge and wound prevalence between 2015 and 2016...
May 26, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28544759/hidradenitis-suppurativa-complicated-by-squamous-cell-carcinoma-isoscartopic-response
#17
LETTER
Stefano Caccavale, Tobia Caccavale, Maddalena La Montagna
No abstract text is available yet for this article.
May 25, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28508548/a-prospective-evaluation-of-methylene-blue-and-gentian-violet-dressing-for-management-of-chronic-wounds-with-local-infection
#18
Kevin Y Woo, Jolene Heil
The objective of this prospective, non-randomised study was to evaluate the performance of an antibacterial foam dressing containing methylene blue and gentian violet (Hydrofera Blue Classic dressing(®) ) for the management of chronic wounds with local infection. Patients in this study were ≥18 years of age (n = 29), and each had at least one chronic wound ≥1 cm(2) in size that showed signs of localised infection or critical colonisation but with good potential for healing based on clinical assessment...
May 16, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28503756/biofilms-and-delayed-healing%C3%A2-%C3%A2-an-in-vitro-evaluation-of-silver-and-iodine-containing-dressings-and-their-effect-on-bacterial-and-human-cells
#19
Katie A Bourdillon, Craig P Delury, Breda M Cullen
This study investigated whether there are differences in the ability of wound dressings to modulate certain factors known to affect wound healing. A selection of antimicrobial dressings (AQUACEL(®) Ag Extra(™) , AQUACEL(®) Ag+ Extra(™) , IODOFLEX(™) , ACTICOAT(™) 7 and PROMOGRAN PRISMA(™) matrix) were tested for their effect on both bacterial bioburden and human dermal fibroblasts. Some dressings underwent further evaluation for activity against Pseudomonas aeruginosa biofilms using a colony-drip flow reactor model...
May 14, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28488305/the-use-of-medicinal-plants-in-venous-ulcers-a-systematic-review-with-meta-analysis
#20
Anderson L Freitas, Carla A Santos, Carlos As Souza, Marco Ap Nunes, Ângelo R Antoniolli, Wellington B da Silva, Francilene A da Silva
The aim of this study was to systematically review the use of medicinal plants for the treatment of varicose ulcers. The databases used in the search were: Medline/Pubmed, Scopus, Cinhal, Lilacs and Web of Science. The selection process was divided into two phases: the reading of titles and abstracts and the full reading of selected articles. The item description was compared with the checklist of the Consolidated Standards of Reporting Trials. The initial search produced 3505 articles and seven were selected for inclusion in the systematic review...
May 9, 2017: International Wound Journal
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