L Fishchuk, O Lobanova, Z Rossokha, V Cheshuk, R Vereshchako, Yu Vagyn, V Kashuba, V Vershyhora, O Popova, N Levkovich, O Zemlianska, O Ievseienkova, S Podolska, N Gorovenko
BACKGROUND: Currently, there is a great interest in the genetic testing of BRCA1 and BRCA2 due to the fact that for patients with breast cancer (BC) with pathogenic variants of these genes, the use of the PARP inhibitors could be also provided in addition to implemented treatment protocols. The aim of this study was to characterize the molecular genetic structure of the BRCA1 gene in BC patients without progenitor germline mutations taking into account the methylation state of the promoter region...
October 11, 2023: Experimental Oncology