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Journal of Oral and Maxillofacial Pathology: JOMFP

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[This corrects the article on p. 145 in vol. 22, PMID: 29731576.].
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Manisha Nanasaheb Pandhare, D Bhavthankar Jyoti, Mandakini S Mandale, R Barpande Suresh
"Vascular malformations" comprise a group of lesions, formed by an anomalous proliferation of angiovascular or lymphovascular structures. Arteriovenous malformations (AVMs) are high-flow malformation, characterized by direct communication between arteries and veins, lacking normal capillary network. AVMs are usually congenital. Acquired AVMs are reported to occur due to trauma or hormonal changes. Acquired AVMs, though rare in oral cavity, when present are persistent and progressive in nature and can represent a lethal benign disease...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Shruthi Rangaswamy, Madhumati Singh, Ranjeeta Yumnum
Median palatal cyst is rare nonodontogenic lesion as it represents only 7.14% of all jaw cysts. Also called mid palatal cyst has raised controversy about pathogenesis of such fissural cysts. Specific diagnostic criteria have been described for true median palatal cyst after it has been excluded from WHO classification. The purpose of this paper is to report a rare case of true median palatal cyst satisfying these criteria and discuss current controversy about these cysts.
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Jigna S Shah, Sheetal Sharma, Mahalaxmi Panda
The angiomyxomas are rarely reported in the head and neck region; this paper entails a case of aggressive angiomyxoma presenting as a growth in the maxillary anterior alveolar mucosa and lip region for 1 year, which was accurately identified and treated successfully by surgical excision. An attempt has been made to highlight the clinical and pathologic stand out features of this tumor with intricate emphasis, alongside a literary review.
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Tabita Joy, Jagdish Vishnu Tupkari, Amrut V Hanchate, Pooja Siwach
Rhabdomyosarcoma is a malignant neoplasm of mesenchymal cells, showing varying degrees of striated muscle cell differentiation. It predominantly occurs in children while rarely found in adults and involvement of the oral cavity accounts for only 10%-12% of all head-and-neck cases. Herewith, we present a rare case of spindle cell rhabdomyosarcoma in a 52-year old male, involving the mandibular gingiva, and describe the clinical, radiological, histopathological and immunohistochemical findings.
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Kalavani Peddapelli, Guttikonda Venkateswara Rao, Taneeru Sravya, Sravya Ravipati
Basaloid squamous cell carcinoma (BSCC) is a histologically distinct variant of SCC in the head-and-neck region it occurs most commonly in older men with a history of heavy smoking and alcohol abuse and usually presents as a high stage disease with widespread metastases and hence poor prognosis. BSCC is believed to arise from a totipotential primitive cell in the basal layer of the surface epithelium or from the salivary duct lining epithelium. BSCC is an uncommon tumor with a predilection for the upper aerodigestive tract, is a distinct variant of squamous carcinoma, due to its unique histological features and ominous clinical behavior...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Suhasini Gotur Palakshappa, Vijay Wadhwan, Vishal Bansal, Nagaraju Kamarthi
Multiple myeloma (MM) is a relatively rare malignant hematological disease, which is characterized by a monoclonal malignant proliferation of plasma cells that causes osteolytic lesions. Maxillofacial presentations in patients with MM are not uncommon, but because the symptoms are varied, it is very difficult to diagnose MM in this region especially in patients with initial oral involvement. Furthermore, maxillofacial manifestations as an initial sign or symptom are scarce. We report a case of a 40-year-old male patient who presented with an unhealed socket in lower left back tooth region for the past 2 months...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Sowmya Kasetty, Dhara Dwivedi, T Raju Ragavendra, Shreenivas Kallianpur, Sandeep Gupta, Nitin Prabhakar
Context: Adequate tissue fixation is fundamental to good quality histological sections. Owing to undesirable effects of 10% buffered formalin, its availability in clinics is questionable. Thus, the present study was conducted with a novel approach to fixation, together with the scope of finding fixative properties of more commonly used reagents available at the clinics. Aims: The present study was aimed to compare the efficacy of local anesthetic solution, normal saline (NS) and distilled water (DW) with that of 10% neutral-buffered formalin...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Bhagyashri Ramachandra Latti, Jitendra V Kalburge, Sanjeev Bhimashankar Birajdar, Ramachandra Girimallappa Latti
Background: Diabetes mellitus is a metabolic disease leading to abnormal fat, carbohydrate and protein metabolism. Reduced salivary flow rate caused by hyperglycemia is characteristic mainly for periods of poor metabolic control of diabetes, thereby facilitating the growth of aciduric bacteria and caries-lesion development. The objective of our study was to evaluate the effects of diabetes mellitus on dental caries micro-organisms responsible for caries. Materials and Methods: This study was carried out on 60 subjects consisting of 2 groups...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Mvr Ratnam, Abhishek Singh Nayyar, D Santhosh Reddy, B Ruparani, K V Chalapathi, Sania Md Azmi
Context: Acquired immunodeficiency syndrome (AIDS) is an acronym for AIDS caused by a retrovirus known as human immunodeficiency virus (HIV) which breaks down the body's immune system leaving a patient vulnerable to a host of life-threatening opportunistic infections, neurological disorders or unusual malignancies. According to estimates by the World Health Organization and UNAIDS, 35 million people were living with HIV globally at the end of 2013. The first AIDS case in India was detected in 1986...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Suchita Sheelam, Shyam Prasad Reddy, Pavan G Kulkarni, Srk Nandan, M Keerthi, G Shyam Raj
Background: Significant increase in cell proliferation and vascularity occurs during the transition from normal oral mucosa through differing degrees of dysplasia to oral squamous cell carcinoma (OSCC). Aims: To evaluate the cell proliferation and vascularity in potentially malignant disorders and OSCC. Settings and Design: Proliferating cell nuclear antigen (PCNA), vascular endothelial growth factor (VEGF) and CD34 were quantified immunohistochemically (IHC) using anti-PCNA, anti-VEGF and anti-CD34 antibody...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Nadia Shirazi, Sampan Singh Bist, Neeti Puri, Meena Harsh, Sohaib Ahmad
Introduction: Sinonasal tumors occur in the nasal cavity or paranasal sinuses (PNS). These tumors are rare and lymphomas are even rarer. Lymphoma of the nose and PNS may mimic benign processes and may manifest either in an isolated fashion or in conjunction with systemic diseases. B-cell lymphomas, a more favorable diagnosis, account for the majority of cases, whereas T-cell and extranodal natural killer lymphoma are associated with rapid disease progression and death. Materials and Methods: All patients with sinonasal lymphomas who were nonreactive for HIV and were operated and treated in our hospital from 2006 to 2016 were included in the study...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Syed Ahmed Taqi, Syed Abdus Sami, Lateef Begum Sami, Syed Ahmed Zaki
Histopathological examination is considered as gold standard procedure for arriving at a final diagnosis of various lesions of the human body. However, it is limited by a number of alterations of normal morphologic and cytological features that occur as a result of presence of artifacts. These artifacts may occur during surgical removal, fixation, tissue processing, embedding and microtomy and staining and mounting procedures. They can even lead to complete uselessness of the tissue. It is therefore essential to identify the commonly occurring artifacts during histopathological interpretations of tissue sections...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Manika Arora, Deepa R Mane
Background: In oral squamous cell carcinoma (OSCC), extracellular matrix metalloproteinase inducer (EMMPRIN) expression has been noted in the cell membrane throughout the epithelium of the lesion, suggesting its increased expression. Objectives: The present study was conducted to evaluate and compare the expression of EMMPRIN in the normal oral mucosa (NOM), different histological grades of oral epithelial dysplasia (OED) and OSCC. Materials and Methods: A total of 100 formalin-fixed paraffin-embedded tissue blocks of NOM ( n = 10), 20 cases each of mild, moderate and severe (OED) ( n = 60), and 10 cases each of well differentiated, moderately differentiated and poorly differentiated carcinomas ( n = 30) were included in the study...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Treville Pereira, Subraj Shetty, Ridima Surve, Swati Gotmare, Pooja Kamath, Sourab Kumar
Background: Identification of an individual is a challenging task in the field of forensic odontology. Sometimes, the identity of individuals by fingerprints is difficult; hence, the examination of palatal rugae and the human dentition is a viable option. Aims and Objectives: The objective of the present study was to determine the sex of an individual and the hereditary pattern using three parameters are as follows: palatine rugae, dimensions of maxillary molar and maxillary canine...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Ruchi Bhuyan, Sandeep Mohanty, Sanat Kumar Bhuyan, Abhisekh Pati, Smita Priyadarshini, Pinali Das
Background: The temporomandibular joint is a hinge joint which is formed by the mandible with articulation of the jaw with the cranium. The morphology of the mandible is evaluated by measuring the gonial angle ramus height and bigonial width. Aim: The aim of this study to investigate the impact of age and gender on ramus height, gonial angle and bigonial width in the dentulous odisha population using digital panaromic radiographs. Materials and Methods: A total of 50 dentulous participants (25 males and 25 females) aged between 10 and 80 years were included in this study...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Rudrayya Shivanand Puranik, Vg Bhagya Shree, Surekha R Puranik, Praveen S Anigol
Sclerosing polycystic adenosis (SPA) was first described in 1996 by Smith et al . and was characterized by resemblance to epithelial proliferative lesions of the breast such as fibrocystic disease and sclerosing adenosis. Etiopathogenetically, it is generally believed to represent a nonneoplastic sclerosing and inflammatory process. The age range is broad (typically fourth decade), with a slight female predilection. The vast majority are parotid lesions, with very few in minor salivary glands. As of 2017, not more than 60 cases have been reported worldwide...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Jeffrey S Marschall, George M Kushner, Brian S Shumway
While generally benign, occasional aggressive histologic features in the melanotic neuroectodermal tumor of infancy (MNTI) have been used to justify a diagnosis of malignancy; this could lead to overtreatment. We report a case with presumed aggressive histologic features that did not recur following conservative treatment. This adds evidence that histologic features are not predictive of clinical behavior in MNTI.
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Karpagaselvi Sanjai, Bhavna Pandey, Divya Shivalingaiah, Harish Muniswamy Kumar
Odontoameloblastoma (OA) is an uncommon mixed odontogenic tumor that contains an ameloblastomatous component and odontoma-like elements, usually seen to occur in the mandible of younger patients. Radiographically, the tumor shows central destruction of bone with extension of cortical plates and calcified structures which have the radiopacity of tooth structure. These may resemble miniature teeth similar to a compound odontoma or occur as large masses of calcified material similar to a complex odontoma. We report a case of a 17-year-old male with a hard solitary, diffuse swelling over the right lower third of the face for 8 months...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Neelampari Parikh, C Nandini, Shikha Jain, Anuj V Mansata
Keratoameloblastoma is an exceptionally rare subtype of ameloblastoma that has been reported <20 times previously in the literature. All present as intraosseous lesions. We report an unusual case of keratoameloblastoma localized in the palate without involving palatal bone, thus presenting as a peripheral lesion. To the best knowledge of the authors, no case of peripheral keratoameloblastoma has been reported in the English literature till now, probably rendering this case to be the first one. Therefore, the purpose of this article is to present a rare and the first case of peripheral keratoameloblastoma with histopathological features of this tumor...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
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