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Prague Medical Report

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https://www.readbyqxmd.com/read/28364574/can-platelet-and-leukocyte-indicators-give-us-an-idea-about-distant-metastasis-in-nasopharyngeal-cancer
#1
Mitat Arıcıgil, Mehmet Akif Dündar, Abitter Yücel, Hamdi Arbağ, Suhayb Kuria Aziz
This study aimes to evaluate platelet and leucocyte indicators, such as the mean platelet volume, platelet distribution width, plateletcrit, white blood cell count, neutrophil to lymphocyte ratio in nasopharyngeal cancer patients and also to evaluate the relationship between these indicators and nasopharyngeal cancer with distant metastasis. The medical records of 118 patients diagnosed with nasopharyngeal cancer in our hospital between January 2006 and August 2015 were reviewed. The nasopharyngeal cancer group was further sub grouped according to the presence or absence of distant metastasis and TNM (tumour - T, node - N, metastasis - M) classification...
2017: Prague Medical Report
https://www.readbyqxmd.com/read/28364573/quantitative-parameters-of-interdental-gingiva-in-chronic-periodontitis-patients-with-ifn-%C3%AE-gene-polymorphism
#2
Nadia Sheibak, Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb
Chronic periodontitis (CP), an infectious disease resulting in inflammation within the periodontal tissue, is the main cause of adult tooth loss. CP is a multi-factorial disorder and the interaction between multiple genetic and environmental factors results in the manifestation of this disease. Recent researches in periodontitis has focused on cytokine gene polymorphisms that play important role in periodontal inflammation, but few studies investigated histological change that occur during CP in the supporting tissue of teeth...
2017: Prague Medical Report
https://www.readbyqxmd.com/read/28364572/comparison-of-cold-technique-tonsillectomy-and-thermal-welding-tonsillectomy-at-different-age-groups
#3
COMPARATIVE STUDY
Arif Sanlı, Gazi Yildiz, Banu Atalay Erdogan, Mustafa Paksoy, Gokhan Altin, Muhammed Ali Ozcelik
The aim of this study is to compare objectively advantages and disadvantages of cold technique tonsillectomy and thermal welding tonsillectomy at the same case. A total of 100 patients, 53 patients younger than 12 years of age and 47 patients elder than 12 years of age, were included in this study. Tonsillectomy was performed by using cold technique on the right side of the palatine tonsils and thermal welding on the left side. Right and left sides were compared regarding perioperative bleeding, surgical dissection time, postoperative pain scale at the 1st and 7th day and postoperative bleeding parameters...
2017: Prague Medical Report
https://www.readbyqxmd.com/read/28364571/3d-multislice-and-cone-beam-computed-tomography-systems-for-dental-identification
#4
REVIEW
Hana Eliášová, Taťjana Dostálová
3D Multislice and Cone-beam computed tomography (CBCT) in forensic odontology has been shown to be useful not only in terms of one or a few of dead bodies but also in multiple fatality incidents. 3D Multislice and Cone-beam computed tomography and digital radiography were demonstrated in a forensic examination form. 3D images of the skull and teeth were analysed and validated for long ante mortem/post mortem intervals. The image acquisition was instantaneous; the images were able to be optically enlarged, measured, superimposed and compared prima vista or using special software and exported as a file...
2017: Prague Medical Report
https://www.readbyqxmd.com/read/28364570/excessive-fragmentary-myoclonus-what-do-we-know
#5
REVIEW
Jiří Nepožitek, Karel Šonka
Excessive fragmentary myoclonus (EFM) is a polysomnographic finding registered by the surface electromyography (EMG) and characterized as a result of the muscle activity consisting of sudden, isolated, arrhythmic, asynchronous and asymmetric brief twitches. The EMG potentials are defined by the exact criteria in The International Classification of the Sleep Disorders, 3rd edition and they appear with high intensity in all sleep stages. Clinical significance of EFM is unclear. It was observed in combination with other diseases and features such as obstructive and central sleep apnea, narcolepsy, periodic limb movements, insomnia, neurodegenerative disorders and peripheral nerve dysfunction...
2017: Prague Medical Report
https://www.readbyqxmd.com/read/27930897/percutaneous-nephrolithotomy-in-a-patient-with-mainz-pouch-ii-urinary-diversion-a-case-report
#6
Stavros Sfoungaristos, Ioannis Mykoniatis, Evangelos Poulios, Dimitrios Paikos, Dimitrios Hatzichristou
Mainz pouch II is a reliable and viable technique of continent urinary diversion. Patients are at increased risk of long-term complications including urolithiasis of the upper urinary tract and reservoir. We report the case of a 67-year-old male with prior Mainz pouch II due to invasive bladder cancer treated for a large renal calculus. Percutaneous nephrolithotomy (PCNL) was successfully performed. Stone management in these type of patients is of increased interest due to existed "anatomical challenges" concerning the access and safety during the procedure...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27930896/can-anxiety-tested-in-the-elevated-plus-maze-be-related-to-nociception-sensitivity-in-adult-male-rats
#7
Marie Pometlová, Anna Yamamotová, Kateryna Nohejlová, Romana Šlamberová
Methamphetamine (MA) is one of the most addictive psychostimulant drugs with a high potential for abuse. Our previous studies demonstrated that MA administered to pregnant rats increases pain sensitivity and anxiety in their adult offspring and makes them more sensitive to acute administration of the same drug in adulthood. Because individuals can differ considerably in terms of behaviour and physiology, such as rats that do not belong in some characteristics (e.g. anxiety) to average, can be described as low-responders or high-responders, are then more or less sensitive to pain...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27930895/osteoarthrosis-of-temporomandibular-joint-related-to-the-defects-of-posterior-dentition-a-retrospective-study
#8
Jitka Levorová, Vladimír Machoň, Anasuya Guha, René Foltán
Osteoarthrosis (OA) of temporomandibular joint (TMJ) is a progressive degenerative disease, gradually affecting cartilage, synovial membrane and bone structures. OA of TMJ clinically manifests with joint noises, pain and restricted mouth opening. In late stages, it results in severe damage of TMJ structures and development of ankylosis. Osteoarthrosis is a multifactorial disease; the occurrence is associated with TMJ overloading. The cohort included 619 patients [538 women (87%) and 81 men (13%), with average age 40...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27930894/the-i-gel-supraglottic-airway-as-a-conduit-for-fibreoptic-tracheal-intubation-a-randomized-comparison-with-the-single-use-intubating-laryngeal-mask-airway-and-ctrach-laryngeal-mask-in-patients-with-predicted-difficult-laryngoscopy
#9
RANDOMIZED CONTROLLED TRIAL
Pavel Michálek, Will Donaldson, Francis McAleavey, Alexander Abraham, Rachel J Mathers, Claire Telford
Fibreoptic intubation through a supraglottic airway is an alternative plan for airway management in difficult or failed laryngoscopy. The aim of this study was to compare three supraglottic airways as conduits in patients with at least one predictor for difficult laryngoscopy. The i-gel was compared with the single-use intubating laryngeal mask airway (sILMA) and CTrach laryngeal mask in 120 adult patients scheduled for elective surgeries under general anaesthesia using a prospective, randomized and single-blinded design...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27930893/severe-snakebite-envenoming-in-intensive-care
#10
REVIEW
Jiří Valenta, Zdeněk Stach, Pavel Michálek
Snakebites by exotic venomous snakes can cause serious or even life-threatening envenoming. In Europe and North America most victims are breeders, with a few snakebites from wild native American rattlesnakes. The envenomed victims may present in organ and/or system failure with muscle paralysis, respiratory failure, circulatory instability, acute kidney injury, severe coagulation disorder, and local disability - compartment syndrome and necrosis. Best managed by close collaboration between clinical toxicology and intensive care, most severe envenomings are managed primarily by intensive care physicians...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27930892/novel-approaches-in-pilonidal-sinus-treatment
#11
REVIEW
Arda Isik, Oguz Idiz, Deniz Firat
Pilonidal sinus is a very common inflammatory disease of the gluteal region. The ideal method of pilonidal sinus treatment should have a low recurrence rate with minimum excision. Moreover, the treatment method should have a short hospitalization time, should let the patient return to his normal life rapidly, should cause minimum loss of labour and should result a small scar only. In the presented review, modalities in pilonidal sinus treatment in the light of current information in the literature are evaluated...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27668530/bone-metabolism-of-the-patient-with-a-malignant-melanoma-during-the-entry-examination-and-the-check-up-of-whole-body-bone-scintigraphy
#12
Jaroslav Weissensteiner, Eva Babušíková
Malignant melanoma is a malignancy located predominantly in the skin and the incidence of melanoma increases. We compared the markers of bone metabolism - osteocalcin (OC), beta-carboxyterminal cross-linked telopeptide of type I collagen (β-CrossLaps, β-CTx) and tumour marker - human epididymis protein 4 (HE4) in the serum with finding during the entry examination and the check-up of whole-body bone scintigraphy of the patient with a malignant melanoma. Serum concentrations of OC, β-CTx, HE4 were determined in 1 patient (female, age 64 years) with malignant melanoma and correlated with the presence of equivocal bone metastases detected by whole-body bone scintigraphy (the entry examination and check-up after 6 months)...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27668529/igg4-related-diseases-a-rare-polycystic-form-of-ormond-s-disease
#13
Miroslav Průcha, Petr Czinner, Petra Prokopová
Currently, Ormond's disease is classified among IgG4-associated diseases. Its clinical manifestation varies and is characterized by the presence of fibrous retroperitoneal tissue that often affects the ureters or abdominal aorta and iliac arteries. We present a unique case of the polycystic form of Ormond's disease, imitating tumour in the retroperitoneal space. At the time of diagnosis, the disease was not metabolically active and did not require immunosuppressive therapy. The polycystic mass was removed surgically...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27668528/thoracic-outlet-syndrome-a-significant-family-genetic-phenotypic-presentation
#14
David Janák, Karel Novotný, Miloslav Roček, Vilém Rohn
We report on a very rare case of diagnosis and successful surgical treatment of three young family members with a four-fold presentation of thoracic outlet syndrome. In the relevant family case, we are considering and discussing the population incidence, a possible HOX genes disorder, and a significant phenotypic presentation.
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27668527/the-effect-of-infliximab-on-intestinal-anastomosis-healing-in-rats
#15
Oktay Karaköse, Hüseyin Eken, Ali Naki Ulusoy, Hüseyin Koray Topgül, Mehmet Bilgin, Saim Savaş Yürüker, Mustafa Yavuz Gülbahar
Intestinal anastomosis healing is a complex physiological process in which many local and systemic factors play a role. One of the significant cytokines in this process is TNF-α. Infliximab is a chimeric monoclonal antibody which binds to TNF-α with high affinity. Although this agent is used in ulcerative colitis and Crohn's disease, intestinal surgery may be required in these patients. In this study it was aimed to determine whether or not there was any negative effect of preoperative single dose infliximab treatment on intestinal anastomosis healing...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27668526/the-response-of-c19-%C3%AE-5-steroids-to-acth-stimulation-and-hypoglycemia-in-insulin-tolerance-test-for-adrenal-insufficiency
#16
COMPARATIVE STUDY
Michaela Dušková, Lucie Kolátorová Sosvorová, Martin Hill, Kateřina Šimůnková, Hana Jandíková, Hana Pospíšilová, Monika Šrámková, Mikuláš Kosák, Michal Kršek, Václav Hána, Luboslav Stárka
Studies on the time course of ACTH- or insulin-induced hypoglycemia stimulating adrenal androgens are usually limited to dehydroepiandrosterone and/or its sulphate. Our data on dehydroepiandrosterone (DHEA) and its hydroxylated metabolites clearly show that measurements of DHEA and its sulphate (DHEAS) are valuable markers of the integrity of the HPA (hypothalamus-pituitary-adrenal) axis. Assessments of HPA function should rely on measurements of baseline and/or stimulated serum cortisol concentrations, and C19 Δ5-steroids may provide additional information...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27668525/ccl5-rs2107538-polymorphism-increased-the-risk-of-tuberculosis-in-a-sample-of-iranian-population
#17
COMPARATIVE STUDY
Hamid Reza Kouhpayeh, Mohsen Taheri, Mana Baziboroon, Mohammad Naderi, Gholamreza Bahari, Mohammad Hashemi
Cysteine-cysteine chemokine ligand 5 (CCL5) with immunoregulatory and inflammatory activities has an important role in granuloma formations that activates and stimulates T-cells and macrophages. Cysteine-cysteine chemokine receptor 5 (CCR5) is a chemokine receptor, which is important for migration of immune cells to site of infection. In the present study we investigated the possible association between CCL5 -403G/A (rs2107538), CCL5 -28C/G (rs2280788) and CCR5 Δ32 polymorphisms and pulmonary tuberculosis (PTB) in an Iranian population...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27668524/smoking-prevalence-and-its-clinical-correlations-in-patients-with-narcolepsy-cataplexy
#18
Pavla Peřinová, Eva Feketeová, David Kemlink, Petra Kovalská, Karolína Chlebušová, Jiří Nepožitek, Veronika Ibarburu, Eva Králíková, Soňa Nevšímalová, Karel Šonka
Narcolepsy-cataplexy (NC) is a chronic neurological disease with suggested autoimmune etiopathogenesis. Nicotine stimulates central nervous system and smoking increases the risk of autoimmune diseases. Assessment of smoking habits and its correlation to clinical parameters among 87 adult NC patients (38 male, 49 female) included night polysomnography and multiple sleep latency test. In our sample, 43.7% NC patients were regular smokers, and 19.5% former smokers compared to 22.2%, and 12.6%, respectively, in the general population...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/26995205/terlipressin-induced-severe-hyponatremia
#19
Martin Šíma, Miroslav Pokorný, František Paďour, Ondřej Slanař
Terlipressin is a vasopressin analogue used for its vasoconstrictor effect in the treatment of variceal bleeding. Despite its good safety profile compared to vasopressin, some adverse reactions may occur during its use - e.g. hyponatremia. We describe a case of a cirrhotic patient with active variceal bleeding treated during two separate hospitalizations with terlipressin. In both drug treatment periods, severe laboratory hyponatremia developed. After terlipressin discontinuation, mineral disbalance corrected rapidly...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/26995204/snakebite-envenoming-by-sochurek-s-saw-scaled-viper-echis-carinatus-sochureki
#20
Jiří Valenta, Zdeněk Stach, Pavel Michálek
A snake breeder, 47-years-old man, was bitten by the saw-scaled viper (Echis carinatus sochureki). After admission to Toxinology Centre, within 1.5 h, laboratory evaluation showed clotting times prolonged to non-measurable values, afibrinogenaemia, significantly elevated D-dimers, haemolysis and myoglobin elevation. Currently unavailable antivenom was urgently imported and administered within 10 hours. In 24 hours, oligoanuric acute kidney injury (AKI) and mild acute respiratory distress syndrome (ARDS) developed...
2016: Prague Medical Report
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