Read by QxMD icon Read

Canadian Journal of Infectious Diseases & Medical Microbiology

Giovanni Bruno, Giulia Rocco, Piera Zaccari, Barbara Porowska, Maria Teresa Mascellino, Carola Severi
Helicobacter pylori ( Hp ) is responsible for one of the most common infections in the world. The prevalence exceeds 50% of the population in developing countries, and approximately one-third of the adults are colonized in North Europe and North America. It is considered a major pathogenic agent of chronic gastritis, peptic ulcer, atrophic gastritis, gastric cancer, and mucosa-associated lymphoid tissue lymphoma (MALT). Hp colonization modifies the composition of gastric microbiota that could drive the development of gastric disorders...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Kamal Dumaidi, Amer Al-Jawabreh, Fekri Samarah, Maha Rabayaa
Background: HCV and HBV present a great challenge in the management of β -thalassemia patients. Objective: The present study aimed to determine the prevalence of both HBV and HCV in multitransfused-dependent β -thalassemia patients in northern West Bank, Palestine, using sero-molecular markers. Methods: Serum sample from 139 multitransfused β -thalassemia patients were tested for HBV and HCV markers including HBsAg, anti-HBc, anti-HBs, HBV-DNA, and anti-HCV and HCV-RNA...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Leidy Diana Piedrahita, Ivony Y Agudelo Salas, Katherine Marin, Andrea I Trujillo, Jorge E Osorio, Sair Orieta Arboleda-Sanchez, Berta Nelly Restrepo
Dengue fever is an increasing health problem in tropical and subtropical regions. During 2010 in Medellin, the younger population presented a particularly high dengue incidence rate. This study estimated dengue virus (DENV) transmission in schoolchildren (aged 5-19 years) in Medellin from 2010 to 2012. A longitudinal serological survey (IgG) and spatial analysis were conducted to determine the distribution of DENV seroprevalence. A total of 4,385 schoolchildren participated for at least one year. Dengue seroprevalence significantly increased during the studied period (53...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Ewa Trejnowska, Aleksander Deptuła, Magda Tarczyńska-Słomian, Piotr Knapik, Miłosz Jankowski, Agnieszka Misiewska-Kaczur, Barbara Tamowicz, Jakub Śmiechowicz, Remigiusz Antończyk, Paul Armatowicz, Wiktor Sułkowski, Grażyna Durek
Antibiotic use and microbial resistance in health care-associated infections are increasing globally and causing health care problems. Intensive Care Units (ICUs) represent the heaviest antibiotic burden within hospitals, and sepsis is the second noncardiac cause of mortality in ICUs. Optimizing appropriate antibiotic treatment in the management of the critically ill in ICUs became a major challenge for intensivists. We performed a surveillance study on the antibiotic consumption in 108 Polish ICUs. We determined which classes of antibiotics were most commonly consumed and whether they affected the length of ICU stay and the size and category of the hospital...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Govinda Maharjan, Priyatam Khadka, Gomik Siddhi Shilpakar, Ganesh Chapagain, Guna Raj Dhungana
Background: Biofilms, or colonies of uropathogen growing on the surface of indwelling medical devices, can inflict obstinate or recurring infection, thought-provoking antimicrobial therapy. Methods: This prospective analysis included 105 urine samples from catheterized patients receiving intensive care. Ensuing phenotypic identification, antibiotic sensitivity test was performed by modified Kirby-Bauer disc diffusion method following CLSI guidelines; MDR isolates were identified according to the combined guidelines of the European Centre for Disease Prevention and Control (ECDC) and the Centers for Disease Control and Prevention (CDC)...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Won-Young Kim, Eun Suk Jeong, Insu Kim, Kwangha Lee
Purpose: The aim of this pre- and postintervention cohort study was evaluating how effectively rapid pathogen identification with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) detected the causative organisms in sepsis. Methods: All consecutive adult patients who had bacteremia within 72 h of intensive care unit admission and met ≥2 quick Sequential Organ Failure Assessment criteria at intensive care unit admission were analyzed...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Ying Wang, Xinjie Liu, Qi Liu
Streptococcus pneumoniae meningitis is one of the most common disorders seen in clinical practice. It is believed that the brain tissue immune injury is caused by the expression of pattern-recognition receptors (PRR) which can further induce the release of other cytokines and inflammatory cascades. The aim of this study is to investigate the expression of nucleotide-binding oligomerization domain 2 (NOD2) and inflammatory factors in rat brain tissues infected with Streptococcus pneumoniae and its influence on the blood-brain barrier (BBB) permeability...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Liliana Simões-Silva, Susana Ferreira, Carla Santos-Araujo, Margarida Tabaio, Manuel Pestana, Isabel Soares-Silva, Benedita Sampaio-Maia
Peritoneal dialysis-related infections are important morbidity/mortality causes, being staphylococci the most prevalent agents. Since Staphylococcus aureus nasopharynx carriage is a known risk factor for PD infections and the oral cavity is a starting point for systemic diseases development, we aimed at comparing the oral staphylococci colonization between PD patients and controls and studying the association with PD-related infections. Saliva samples were plated in Mannitol salt, and isolates were identified by DnaJ gene sequencing...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Joel H Elizondo-Luévano, Rocío Castro-Ríos, Eduardo Sánchez-García, Magda E Hernández-García, Javier Vargas-Villarreal, Osvelia E Rodríguez-Luis, Abelardo Chávez-Montes
Infections caused by parasites in humans represent one of the main public health concerns. Amoebiasis, a parasitic infection caused by Entamoeba histolytica ( E. histolytica ), is considered endemic in Mexico, where Argemone mexicana ( A. mexicana ) has been used in traditional medicine to treat intestinal parasitic diseases. The objective of this work was to evaluate the potential biological activity of A. mexicana on E. histolytica . For this purpose, a methanolic extract was prepared from A. mexicana leaves, and a differential fractionation was carried out with solvents of different polarities...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Aline Z de Azambuja, Gustavo Wissmann Neto, Guilherme Watte, Luciana Antoniolli, Luciano Z Goldani
Objective: Cryptococcus neoformans is a common opportunistic infection in adults with acquired immunodeficiency syndrome worldwide. However, limited data exist for HIV-infected patients in the post-HAART (highly active antiretroviral therapy) era in Brazil. The aim of this study was to describe the clinical characteristics and outcomes of cryptococcosis in a cohort of patients attending a teaching tertiary care hospital in southern Brazil after the introduction of HAART in Brazil. Patients and Methods: A retrospective study was conducted in tertiary care hospital in southern Brazil...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Zong-Yen Wu, Po-Yu Liu, Shu-Ying Tseng, Yi-Hsuan Lee, Shu-Peng Ho
Shewanella haliotis is an emerging human pathogen. Many infectious cases were linked to shellfish ingestion or aquatic exposure. Therefore, it is important to study the phylogeny and distribution of S. haliotis in shellfish aquaculture. We investigated the distribution of S. haliotis in cultivated shellfish farming in Taiwan in which S. haliotis was found in the shellfish from all sampling sites. S. haliotis was identified in cultivated shellfish by 16S rRNA gene sequencing, such as abalone ( Haliotis diversicolor ), clam ( Meretrix lusoria ), and oyster ( Crassostrea gigas )...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Kanchana Bandara, Chinthika Gunasekara, Manjula Weerasekera, Chamil Marasinghe, Nilantha Ranasinghe, Neluka Fernando
Objectives: The aim of this study was to determine the level of five different pro- and anti-inflammatory cytokines to study the inflammatory response of leptospirosis. Materials and methods: The serum cytokine levels of IL-10, IL-17A, IL-21, IL-23, and TNF- α were investigated in 57 patients with leptospirosis and 12 healthy controls using a commercially available ELISA kit (Mabtech, Sweden). Statistical analysis was done using Graphpad Prism. Results: Elevation of serum IL-10 and IL-17A levels and significant elevation of serum IL-21 ( p =0...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Jialiang Yang, Bo Liao, Jianqiang Ye, Taoyang Wu
No abstract text is available yet for this article.
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Alejandro A Hidalgo, Ángel J Arias, Juan A Fuentes, Patricia García, Guido C Mora, Nicolás A Villagra
Increased resistance to antimicrobials in clinically important bacteria has been widely reported. The major mechanism causing multidrug resistance (MDR) is mediated by efflux pumps, proteins located in the cytoplasmic membrane to exclude antimicrobial drug. Some efflux pumps recognize and expel a variety of unrelated antimicrobial agents, while other efflux pumps can expel only one specific class of antibiotics. Previously, we have reported that xylose decreases the efflux-mediated antimicrobial resistance in Salmonella typhimurium , Pseudomonas aeruginosa , and Acinetobacter baumannii in vitro ...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Catia A Almeida, Mariana M B Azevedo, Francisco C M Chaves, Marcelo Roseo de Oliveira, Igor A Rodrigues, Humberto R Bizzo, Paola E Gama, Daniela S Alviano, Celuta S Alviano
Piper is the largest genus of the Piperaceae family. The species of this genus have diverse biological activities and are used in pharmacopeia throughout the world. They are also used in folk medicine for treatment of many diseases in several countries including Brazil, China, India, Jamaica, and Mexico. In Brazil, Piper species are distributed throughout the national territory, making this genus a good candidate for biological activity screening. During our studies with Piper essential oils, we evaluated its activity against Rhizopus oryzae , the main agent of mucormycosis...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Daniel W Gunda, Simon C Maganga, Igembe Nkandala, Semvua B Kilonzo, Bonaventura C Mpondo, Elichilia R Shao, Samwel E Kalluvya
Introduction: Although ART has improved the outcome of people living with HIV/AIDS, still some patients develop TB while receiving ART. The literature on the magnitude of this problem is still scarce in our setting especially northwestern Tanzania. This study was designed to determine the prevalence of active TB among HIV patients on ART and assess its potential risk factors. Methods: A retrospective cohort study was done among adult HIV-positive patients initiated on ART at Bugando Medical Centre...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Tonny Loho, Ninik Sukartini, Dalima A W Astrawinata, Suzanna Immanuel, Diana Aulia, Ika Priatni
Evaluation of the in vitro interaction of doripenem and amikacin against Acinetobacter baumannii , Pseudomonas aeruginosa , and Klebsiella pneumoniae was done by classifying them into four groups: doripenem and amikacin sensitive (DOR-S/AMK-S), doripenem sensitive and amikacin resistant (DOR-S/AMK-R), doripenem resistant and amikacin sensitive (DOR-R/AMK-S), and both doripenem and amikacin resistant (DOR-R/AMK-R). The MIC of each antibiotic and their combination was obtained using the Etest method. The fractional inhibitory concentration index was calculated to classify the results as synergistic, additive, indifferent, or antagonistic interaction...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
George G Zhanel, Michael A Zhanel, James A Karlowsky
Fosfomycin is a bactericidal agent that inhibits cell wall synthesis using a mechanism of action distinct from β -lactams or other antimicrobial agents. It is a broad-spectrum agent that is frequently active against antimicrobial-resistant bacterial pathogens including methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), multidrug-resistant (MDR) Enterobacteriaceae, and some isolates of MDR Pseudomonas aeruginosa . Intravenous fosfomycin has been prescribed for a wide variety of infections in many countries for >40 years...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Bai Jun Sun, Hui Jie Chen, Ye Chen, Xiang Dong An, Bao Sen Zhou
Objectives: The incidence of severe hand, foot, and mouth disease (HFMD) is not low, especially in mainland China in almost every year recently. In this study, we conducted a meta-analysis to generate large-scale evidence on the risk factors of severe HFMD to provide suggestions on prevention and controlling. Methods: PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), and Wanfang (Chinese) were searched to identify relevant articles...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Suntorn Pimnon, Adisak Bhumiratana
Anthropogenic activity such as the establishment of Anopheles -infested rubber plantations can influence local malaria transmission dynamics to which the population dynamics and insecticide susceptibility of local Anopheles vectors are related. Using human landing catch collections at a house protected by indoor residual spraying (IRS), the periodic assessment of species composition, abundance, and blood-feeding behaviors was done in pre-IRS, during IRS, and post-IRS at 3, 6, and 12 months in a malaria-associated rubber plantation (MRP) ecotope of the Bo Rai district, Trat Province, Thailand, after malaria outbreak occurred...
2018: Canadian Journal of Infectious Diseases & Medical Microbiology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"