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Canadian Journal of Infectious Diseases & Medical Microbiology

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https://www.readbyqxmd.com/read/29445406/detection-and-molecular-characterization-of-human-adenovirus-infections-among-hospitalized-children-with-acute-diarrhea-in-shanghai-china-2006-2011
#1
Lijuan Lu, Huaqing Zhong, Liyun Su, Lingfeng Cao, Menghua Xu, Niuniu Dong, Jin Xu
Background : Human adenovirus (HAdV) is considered a significant enteropathogen associated with sporadic diarrhea in children. However, limited data are available regarding the epidemiology of HAdV in hospitalized children with viral diarrhea in Shanghai. The aim of this study was to characterize the epidemiology of HAdVs and describe their association with acute diarrhea in hospitalized children. Methods : A total of 674 fecal samples were subjected to PCR or RT-PCR to detect RVA, HuCV, HAstV, and HAdV. Results : HAdV infections were detected in 4...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/29430252/oral-yeast-colonization-and-fungal-infections-in-peritoneal-dialysis-patients-a-pilot-study
#2
Liliana Simões-Silva, Sara Silva, Carla Santos-Araujo, Joana Sousa, Manuel Pestana, Ricardo Araujo, Isabel Soares-Silva, Benedita Sampaio-Maia
Peritonitis and exit-site infections are important complications in peritoneal dialysis (PD) patients that are occasionally caused by opportunistic fungi inhabiting distant body sites. In this study, the oral yeast colonization of PD patients and the antifungal susceptibility profile of the isolated yeasts were accessed and correlated with fungal infection episodes in the following 4 years. Saliva yeast colonization was accessed in 21 PD patients and 27 healthy controls by growth in CHROMagar-Candida® and 18S rRNA/ITS sequencing...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/29410684/the-incidence-of-acute-gastrointestinal-illness-in-canada-foodbook-survey-2014-2015
#3
M Kate Thomas, Regan Murray, Andrea Nesbitt, Frank Pollari
Acute gastrointestinal illness (AGI) is an important public health issue, with many pathogen sources and modes of transmission. A one-year telephone survey was conducted in Canada (2014-2015) to estimate the incidence of self-reported AGI in the previous 28 days and to describe health care seeking behaviour, using a symptom-based case definition. Excluding cases with respiratory symptoms, it is estimated that there are 0.57 self-reported AGI episodes per person-year, almost 19.5 million episodes in Canada each year...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/29391872/in-vitro-assessment-of-antifungal-caspofungin-on-leishmania-donovani-culture-isolation
#4
Narayan Raj Bhattarai, Keshav Rai, Suman Rijal, Basudha Khanal
Leishmania parasite isolation from the human aspirates is always challenging due to most probability of the fungal contamination and the use of antifungal drug which could support the selective growth of the Leishmania parasite. In this study, we examine the effect of antifungal drug caspofungin on the promastigote stage of Leishmania donovani. Promastigote parasite was cultivated in M199 + 20% heat-inactivated fetal calf serum and plated in 96-well plates. Seven different concentrations of caspofungin (512 µg/ml to 8 µg/ml) were exposed to parasites, and 50% inhibitory concentration (IC50) was calculated...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/29379527/clinical-and-mortality-risk-factors-in-bloodstream-infections-with-carbapenem-resistant-enterobacteriaceae
#5
Xiaopeng Li, Huan Ye
Objective: To investigate the risk factors underlying the occurrence and mortality of bloodstream infections (BSIs) with carbapenem-resistant Enterobacteriaceae (CRE). Methods: Medical information was retrospectively analyzed from 148 cases of patients with Enterobacteriaceae BSIs at a medical center in China, between 2013 and 2015. Results: The 30-day mortality rate in the CRE group was 65.4%. Indwelling urethral catheterization, admission to the ICU, use of antibiotics within 30 days, and BSIs from the respiratory system were associated with CRE BSIs...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/29348763/inflammasomes-in-mycobacterium-tuberculosis-driven-immunity
#6
REVIEW
Sebastian Wawrocki, Magdalena Druszczynska
The development of effective innate and subsequent adaptive host immune responses is highly dependent on the production of proinflammatory cytokines that increase the activity of immune cells. The key role in this process is played by inflammasomes, multimeric protein complexes serving as a platform for caspase-1, an enzyme responsible for proteolytic cleavage of IL-1β and IL-18 precursors. Inflammasome activation, which triggers the multifaceted activity of these two proinflammatory cytokines, is a prerequisite for developing an efficient inflammatory response against pathogenic Mycobacterium tuberculosis (M...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/29230252/evaluation-of-the-utility-of-point-of-care-hiv-testing-on-a-canadian-internal-medicine-inpatient-unit
#7
Lawrence Lau, Beverly Wudel, Eugene Lee, Majid Darraj, Quinlan Richert, Adriana Trajtman, Kim Bresler, Jared Bullard, Ken Kasper, Marissa Becker, Yoav Keynan
Point-of-care (POC) HIV testing has been shown to be an acceptable method for increasing HIV testing uptake. To date, no studies have examined the use of POC testing for routine HIV screening on the medicine inpatient unit. A prospective cross-sectional study was conducted over a three-month period in July, August, and October 2016 to evaluate the prevalence of undiagnosed HIV and the attitudes towards routine POC HIV testing. Patients admitted directly to medicine inpatient teaching units at a tertiary hospital in Winnipeg, Canada, were approached for participation...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/29181039/epidemiology-and-genetic-diversity-of-colistin-nonsusceptible-nosocomial-acinetobacter-baumannii-strains-from-russia-for-2013-2014
#8
Eugene A Sheck, Mikhail V Edelstein, Marina V Sukhorukova, Natali V Ivanchik, Elena Yu Skleenova, Andrey V Dekhnich, Ilya S Azizov, Roman S Kozlov
A high level of resistance to carbapenems in Acinetobacter baumannii strains severely limits therapeutic possibilities. Colistin is the last resort drug against such strains, although the cases of resistance to this drug have become more frequent. This article presents the epidemiological features and genetic diversity of colistin nonsusceptible A. baumannii strains collected as part of a national multicenter epidemiological study of the antibiotic resistance of pathogens of nosocomial infections (MARATHON), which was conducted in 2013-2014 in Russia...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/29147117/colistin-resistance-of-pseudomonas-aeruginosa-isolated-from-snakes-in-taiwan
#9
Po-Yu Liu, Ling-Ling Weng, Shu-Ying Tseng, Chou-Chen Huang, Ching-Chang Cheng, Yan-Chiao Mao, Kwong-Chung Tung
This study included fifty-eight isolates of P. aeruginosa from the oral cavity of snakes that were recruited from clinical cases, captive and wild snakes. The minimum inhibitory concentrations (MICs) for the determination of susceptibility were identified by the broth microdilution method. Polymerase chain reaction (PCR) was employed to detect β-lactamases genes. With regard to antipseudomonal antibiotics, the lowest nonsusceptible rates were in aztreonam (15%), piperacillin/tazobactam (12%), and amikacin (9%)...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/29081814/roles-of-interferons-in-pregnant-women-with-dengue-infection-protective-or-dangerous-factors
#10
REVIEW
Hao Zhang, Zhiyi He, Wenting Zeng, Hong-Juan Peng
Dengue infection is a serious public health problem in tropical and subtropical areas. With the recent outbreaks of Zika disease and its reported correlation with microcephaly, the large number of pregnancies with dengue infection has become a serious concern. This review describes the epidemiological characteristics of pregnancy with dengue and the initial immune response to dengue infection, especially in IFNs production in this group of patients. Dengue is much more prevalent in pregnant women compared with other populations...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/28932250/evidences-of-the-low-implication-of-mosquitoes-in-the-transmission-of-mycobacterium-ulcerans-the-causative-agent-of-buruli-ulcer
#11
REVIEW
Rousseau Djouaka, Francis Zeukeng, Jude Daiga Bigoga, David N'golo Coulibaly, Genevieve Tchigossou, Romaric Akoton, Sylla Aboubacar, Sodjinin Jean-Eudes Tchebe, Clavella Nantcho Nguepdjo, Razack Adeoti, Innocent Djegbe, Manuele Tamo, Wilfred Fon Mbacham, Solange E Kakou-Ngazoa, Anthony Ablordey
BACKGROUND: Buruli ulcer (BU) continues to be a serious public health threat in wet tropical regions and the mode of transmission of its etiological agent, Mycobacterium ulcerans (MU), remains poorly understood. In this study, mosquito species collected in endemic villages in Benin were screened for the presence of MU. In addition, the ability of mosquitoes larvae to pick up MU from their environment and remain colonized through the larval developmental stages to the adult stage was investigated...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/28852411/prevalence-etiology-and-risk-factors-of-tinea-pedis-and-tinea-unguium-in-tunisia
#12
Nourchène Toukabri, Cyrine Dhieb, Dalenda El Euch, Mustapha Rouissi, Mourad Mokni, Najla Sadfi-Zouaoui
BACKGROUND: Foot mycoses are a frequent disease that represents a public health problem worldwide. OBJECTIVES: This study aims to evaluate the epidemiology of foot mycoses among Tunisian patients, in order to determine the fungal etiological agents and to identify possible risk factors. PATIENTS AND METHODS: A prospective study of three hundred and ninety-two patients was undertaken during one year (2013-2014). All subjects were asked to collect demographic data related to the risk factors of foot mycoses...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/28713434/first-insight-into-a-nationwide-genotypic-diversity-of-mycobacterium-tuberculosis-among-previously-treated-pulmonary-tuberculosis-cases-in-benin-west-africa
#13
Dissou Affolabi, N'Dira Sanoussi, Sergio Codo, Fréderic Sogbo, Prudence Wachinou, Faridath Massou, Aderemi Kehinde, Séverin Anagonou
BACKGROUND: Molecular studies on tuberculosis (TB) are rare in low-resource countries like Benin, where data on molecular study on previously treated TB cases is unavailable. MATERIALS AND METHODS: From January to December 2014, all smear- and culture-positive previously treated pulmonary TB patients from all TB clinics were systematically recruited. Drug susceptibility testing and spoligotyping were performed on all isolates. RESULTS: Of the 100 patients recruited, 71 (71...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/28694832/pathogenicity-of-virulent-species-of-group-c-streptococci-in-human
#14
REVIEW
Marta Kłos, Jadwiga Wójkowska-Mach
Group C streptococci (GCS) are livestock pathogens and they often cause zoonotic diseases in humans. They are Gram-positive, in mostly β-hemolytic and facultative anaerobes. Because of their close evolutionary kinship with group A streptococci (GAS), GCS share many common virulence factors with GAS and cause a similar range of diseases. Due to the exchange of genetic material with GAS, GCS belong to bacteria that are difficult to be distinguished from group A streptococci; GCS are often treated in microbiological diagnostics as contamination of the culture...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/28694831/molecular-identification-of-mycobacterium-species-of-public-health-and-veterinary-importance-from-cattle-in-the-south-state-of-m%C3%A3-xico
#15
Adrian Zaragoza Bastida, Nallely Rivero Pérez, Benjamín Valladares Carranza, Keila Isaac-Olivé, Pablo Moreno Pérez, Horacio Sandoval Trujillo, Ninfa Ramírez Durán
Mycobacterium genus causes a variety of zoonotic diseases. The best known example is the zoonotic tuberculosis due to M. bovis. Much less is known about "nontuberculous mycobacteria (NTM)," which are also associated with infections in humans. The Mexican standard NOM-ZOO-031-1995 regulates the presence of M. bovis in cattle; however, no regulation exists for the NTM species. The objective of this study was to isolate and identify nontuberculous mycobacteria species from cattle of local herds in the south region of the State of Mexico through the identification and detection of the 100 bp molecular marker in the 23S rRNA gene with subsequent sequencing of the 16S rRNA gene...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/28684963/pelvic-actinomycosis
#16
REVIEW
Alejandra García-García, Ninfa Ramírez-Durán, Horacio Sandoval-Trujillo, María Del Socorro Romero-Figueroa
INTRODUCTION: Actinomycosis is a chronic bacterial infection caused by Actinomyces, Gram-positive anaerobic bacteria. Its symptomatology imitates some malignant pelvic tumours, tuberculosis, or nocardiosis, causing abscesses and fistulas. Actinomycoses are opportunistic infections and require normal mucous barriers to be altered. No epidemiological studies have been conducted to determine prevalence or incidence of such infections. OBJECTIVE: To analyse the clinical cases of pelvic actinomycosis reported worldwide, to update the information about the disease...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/28656051/evaluating-the-timeliness-of-enteric-disease-surveillance-in-british-columbia-canada-2012-13
#17
Eleni Galanis, Marsha Taylor, Kamila Romanowski, Olga Bitzikos, Jennifer Jeyes, Craig Nowakowski, Jason Stone, Michelle Murti, Ana Paccagnella, Sara Forsting, Sophie Li, Linda Hoang
Timely surveillance of enteric diseases is necessary to identify and control cases and outbreaks. Our objective was to evaluate the timeliness of enteric disease surveillance in British Columbia, Canada, compare these results to other settings, and recommend improvements. In 2012 and 2013, information was collected from case report forms and laboratory information systems on 2615 Salmonella, shigatoxin-producing E. coli, Shigella, and Listeria infections. Twelve date variables representing the surveillance process from onset of symptoms to case interview and final laboratory results were collected, and intervals were measured...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/28638417/development-and-validation-of-a-decision-making-stratification-algorithm-to-optimize-the-use-of-rapid-diagnostic-testing-for-patients-with-staphylococcus-bacteremia
#18
Thamer A Almangour, Abdullah A Alhifany, Deanne E Tabb
PURPOSE: To evaluate whether introducing rapid diagnostic testing in conjunction with implementing a stratification algorithm for testing eligibility would be an appropriate clinical and cost saving approach. METHOD: An internal concurrent 4-month observational study was performed. Positive blood cultures continued to be worked up in accordance with standard of care. An additional call to the infectious disease (ID) pharmacy service occurred for all positive blood cultures with Gram-positive cocci in clusters (GPCC)...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/28638416/corrigendum-to-detection-of-gastrointestinal-pathogens-from-stool-samples-on-hemoccult-cards-by-multiplex-pcr
#19
Martin Alberer, Nicklas Schlenker, Malkin Bauer, Kerstin Helfrich, Carolin Mengele, Thomas Löscher, Hans Dieter Nothdurft, Gisela Bretzel, Marcus Beissner
[This corrects the article DOI: 10.1155/2017/3472537.].
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/28484498/evaluating-the-trends-of-bloodstream-infections-among-pediatric-and-adult-patients-at-a-teaching-hospital-of-kathmandu-nepal-role-of-drug-resistant-pathogens
#20
Narayan Prasad Parajuli, Hridaya Parajuli, Roshan Pandit, Jyotsna Shakya, Puspa Raj Khanal
Bloodstream infections (BSIs) are among the significant causes of morbidity and mortality for patients of all age groups. However, very little is known about the trends of bacterial bloodstream infections and antimicrobial susceptibilities among pediatric and adult population from Nepal. In this study, we have investigated the different etiological agents responsible for bloodstream infections among pediatric and adult patients and the role of drug resistant organisms in these infections at a tertiary care teaching hospital of Kathmandu, Nepal...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
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