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Georgian Medical News

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https://www.readbyqxmd.com/read/28480868/-working-conditions-and-state-of-health-of-tbilisi-subway-employees
#1
N Khunashvili, Mar Tsimakuridze, L Bakradze, N Khachapuridze, Maya Tsimakuridze
For the purpose of preventive events complex hygienic, clinical-functional, laboratory and biostatic researches are implemented on the basis of Tbilisi Subway. Conditions of work are characterized by complex of unfavorable factors of the working environment and the labor process. Working environment is characterized by combination of unfavorable state of physical factors and air pollution with dust and toxic substances. The levels of noise and vibration refer to the 3.4 class of harmfulness. The content of dust and toxic substances corresponds to 3...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480867/-the-evaluation-of-the-effectiveness-of-the-implementation-of-information-system-1c-enterprise-in-the-hospital
#2
A Baimagambetova, D Kulov, A Tsay, K Kairbekova, M Sakenova
The aim of research was to assess the impact of the introduction of information system 1C: Enterprise on the work of medical staff. It was evaluated staff satisfaction in terms of quality and speed of their duties, as well as sociological changes after the introduction in the work the information system 1C: Enterprise from 2010. The research involved 138 employees of the hospital, including 48 doctors and 90 nurses with experience of at least 5 years. The average age of respondents was 45 years. The study was conducted through questionnaires, including questions relating to life expectancy, changing the speed and quality of execution of tasks, also attended to questions about the change in the frequency of conflict situations and wages...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480866/role-of-primary-health-care-in-re-hospitalization-of-patients-with-heart-failure
#3
T Verulava, N Jincharadze, R Jorbenadze
Re-hospitalization of cardiac patients is a great financial burden not only for healthcare system, but also for patients. Main aim of the research is to identify features and reasons of re-hospitalization and to determine ways of reducing. Within the Quantitative research, we have analyzed data of re-hospitalized patients during 30 days. Within the qualitative study, in-depth survey of medical staff and patient conducted. Main reason of re-hospitalization is that patients do not fulfill doctor's prescriptions after discharging from hospital...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480865/impact-of-food-enriched-with-dietary-fiber-on-patients-with-constipation-predominant-irritable-bowel-syndrome
#4
G Sulaberidze, M Okujava, K Liluashvili, M Tughushi, M Abramashvili
The causes of motility disorder of gastrointestinal tract and in particular Irritable Bowel Syndrome IBS are multifold, leading to complexity of treatment and requirement of more precise investigation of different pharmacological and non-pharmacological approaches. The aim of the study was investigation and comparison of the dietary fiber intake among women with constipation-predominant irritable bowel syndrome (IBS-C) and without, improvement of the dietary fiber intake using interventions with less rough changes of food related behavior and study of its effects on the bowel function, general wellbeing and compliance of patients...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480864/-antiseizure-activity-of-c-ephalaria-gigantea-root-extract
#5
N Gogitidze, N Mushkiashvili, M Gedevanishvili, N Tabatadze, G Dekanosidze
Antiseizure activity of Cephalaria gigantea root extract was studied using PTZ- and/or audiogenic seizure models in outbred Wistar and inbred Krouchinsky- Molodkina rats respectively. In PTZ - model onset of tonic- clonic seizures, latencies to the beginning of the seizure activity, and mortality, and similarly in audiogenic seizures behavioral convulsive reactions , facial automatisms and latency to wild running were evaluated. The extract is used traditionally in Georgian folk medicine as anticonvulsant drug...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480863/effect-of-arsenic-exposure-on-behavior-of-rats-of-various-age-groups
#6
T Bikashvili, T Lordkipanidze, N Gogichaishvili, N Pochkhidze
Arsenic is ranked first among toxicants posing a significant potential threat to human health based on known or suspected toxicity. Recent animal studies suggest that the brain is the major target of arsenic exposure. The present study demonstrates the effect of Arsenic compounds on behavior changes in different age (young and adult) groups of rats. In order to study anxiety behavior, learning and memory processes we used open field, elevated plus maze, spontaneous alteration behavior and multi-branched maze tests...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480862/influence-of-ozone-therapy-on-oral-tissue-in-modeling-of-chronic-recurrent-aphthous-stomatitis
#7
I Kovach, L Kravchenko, Yu Khotimska, R Nazaryan, V Gargin
Chronic recurrent aphthous stomatitis (CRAS) belongs to the group of chronic, inflammatory, ulcerative diseases of the oral mucosa. The aim of this study was to determine the effects of ozone on the morphofunctional peculiarities of the soft tissues in modeling chronic recurrent aphthous stomatitis. We performed experimental investigation for study of the morpho-functional state of tissues of the oral mucosa in CRAS with using of previously proposed and widely used modeling scheme with ovalbumin and aluminum hydroxide...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480861/development-of-the-g-c-m-s-m-s-method-for-qualitative-and-quantitative-determination-of-clozapine-in-human-blood
#8
K Sivsivadze, M Jokhadze, P Tushurashvili, T Murtazashvili, N Imnadze
A simple, rapid, selective, sensitive gas chromatography-mass spectrometry (GC-MS/MS) method was developed and validated for the determination of clozapine in human blood. For isolation was used solid phase extraction. The calibration standards range was 5-1500ng/mL. Analysis was carried out on a gas chromatograph Agilent 7000A Quadrupole GC-MS/MS. GC run conditions - capillary column HP-5MS, 30m × 0.25mm, coated with a 0.25μm film, column temperature from 50°C to 305°C with an increase of 10°C/min; the injection port and the transfer line temperature were 310°C; carrier gas - helium at flow rate of 1...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480860/-research-of-intestinal-microflora-in-the-rats-following-the-internal-and-external-irradiation
#9
Y Kairkhanova, N Chaizhunusоva, M Urazalin, V Stepanenko, M Hоshi
The aim of the research was comparative investigation of the quantitative and qualitative composition of large intestinal microflora following internal (by dispersed powdered 56Mn) and internal exposure of Wistar rats. Ten weeks-old male Wistar rats were used. Rats were divided into four groups: L-56Mn group with 12 rats, H-56Mn with ten rats, 60Co group with nine rats and control group with nine rats. L-56Mn and H-56Mn groups were exposed to two different doses of 56MnO2 powder. 60Co group received 2 Gy of external 60Co γ-ray whole body irradiation...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480859/the-effects-of-non-functional-overreaching-and-overtraining-on-autonomic-nervous-system-function-in-highly-trained-athletes
#10
T Kajaia, L Maskhulia, K Chelidze, V Akhalkatsi, Z Kakhabrishvili
Aim of the study was to compare the ANS functioning, as measured by heart rate variability (HRV), in athletes with non-functional overreaching (NFO) and overtraining syndrome (OTS) and in athletes without NFO/OTS. In 43 athletes with NFO/OTS, 40 athletes without NFO/OTS, as well as in 35 sedentary subjects the ANS function was evaluated with the Autonomic Balance Test, based on the HRV analysis of resting heart rate recordings. Results of the study show lower HRV and lower vagal influence along with increased sympathetic cardiovascular control in athletes with non-functional overreaching and particularly in athletes with overtraining, than in highly trained athletes without NFO/OTS...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480858/-analysis-of-one-carbon-metabolism-genes-and-epidermal-differentiation-complex-in-patients-with-ichthyosis-vulgaris
#11
O Fedota, L Roshchenyuk, I Sadovnychenko, I Merenkova, I Gontar, V Vorontsov
The aim of the study was to evaluate the effects of allelic polymorphism of the FLG and MTHFR genes and their associations in gynecological patients with ichthyosis vulgaris. Gynecological disorders are observed in presence of some forms of ichtyosis. From the prospective of improving nation's healthcare, the greatest attention is drawn to reproductive disorders. Based on this, the research was also tasked with studying of the genetic nature of gynecological diseases, as well as the influence of geographical latitude on the frequencies of mutagenic alleles of the FLG gene and heterogeneous carriers of these mutations...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480857/combined-antiviral-treatment-of-hepatitis-c-virus-infection-with-pegylated-interferon-peg-ifn-%C3%AE-2a-pegferon-and-ribavirin-copegus-in-inmates
#12
E Vashakidze, T Imnadze
The aim of the study was to assess the impact of combined antiviral therapy in prisoners with HCV. In total, 210 patients with chronic C hepatitis have been observed. The patients were divided into 3 groups according to HCV genotype: Group I: - 70 patients infected with genotype 1a/1b; Group II: - 70 patients infected with genotype 2a/2b; Group III: - 70 patients infected with genotype 3a. As for the patients with genotype I: RVR - rapid virological response was negative in 100%; EVR - early virological response was negative in 99%; EOT - end of treatment results was negative in 94% and SVR- sustained virologic response was negative in 91%...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480856/comparative-study-of-fib-4-index-and-transient-elastography-among-patients-with-chronic-hepatitis-c-virus-infection-in-georgia
#13
E Dolmazashvili, M Karchava, A Abutidze, L Sharvadze, T Tsertsvadze
Liver biopsy remains the reference standard for fibrosis staging. However, it has several limitations, which have led to the development of non-invasive methods. We evaluated liver fibrosis severity among HCV infected patients by comparing transient elastography (TE) and FIB-4 index. Retrospective study was conducted. Clinical data for 750 patients were obtained. The mean age of the study population was 51 years; 595 (79.3%) were male and 155 (20.7%) were female. TE and tests on biological samples were performed within one-week timeframe...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480855/plant-aeroallergens-in-two-major-cities-of-georgia-tbilisi-and-kutaisi
#14
T Abramidze, M Gotua, N Chikhelidze, T Cheishvili, A Gamkrelidze
Pollen allergy is caused by a hypersensitivity reaction mainly of the respiratory tract and eye conjunctivae to pollen grains. The number of people allergic to plant aeroallergens has substantially increased in big cities and industrial areas. The monitoring of aerobiological parameters is of paramount importance for the characterization of allergenic risks. The aims of presented study were as follows: to profile the plant aeroallergens in two major cities of Georgia, to compare the character of pollination curves, to determine the dates of beginning of pollen seasons and their duration in particular cities...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480854/unusual-manifestation-of-neuroboreliosis-case-report
#15
M Beridze, N Khizanishvili, M Mdivani, O Samushia, N Gogokhia
The paper reported the verified case of neuroboreliosis with unusual clinical presentation of Parkinsonism. Study aimed at establishing the significance of a precise differential diagnosis with substantial analysis of the symptoms of several diseases to avoid the false diagnosis and to conduct the opportune and adequate therapeutic management. We described the case of the diagnosed neuroboreliosis with clinical expression of Multiple Sclerosis (MS) and Parkinsonism. A 44 years old man was diagnosed as MS according to the McDonald's Criteria, who within two years developed typical clinical signs of Parkinsonism...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480853/-contemporary-approach-to-diagnosis-of-subclinical-heart-failure
#16
A Azaraksh, G Ivanov, N Bulanova, L Stazhadze, M Nikolaeva, V Vostrikov
Treatment of congestive heart failure (CHF) remains one of the challenging problems in cardiology. In recent years, the method of multifrequency bio-impendancemetry is used in patients with CHF for the assessment of water imbalance and determination of its severity. The aim of the study was to determine the diagnostic capabilities of bio-impendancemetry in evaluation of the early manifestations of CHF. The study included 92 healthy individuals, and 335 patients who were hospitalized in the cardiology department with NYHA I-II functional class (FC) of chronic CHF...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480852/-the-influence-of-mono-and-multivascular-lesions-of-coronary-arteries-on-the-course-of-coronary-heart-disease-in-patients-with-diabetes-mellitus-type-2
#17
A Sypalo, P Kravchun, O Kadykova
The article assesses the influence of mono- and multivascular lesions of coronary arteries on the course of coronary heart disease at patients with diabetes mellitus type 2. For this purpose, a comprehensive survey of 75 patients with coronary heart disease and diabetes mellitus type 2 was arranged. Depending on the number of vascular lesions of the coronary arteries, according to the data of coronary arteries computer tomography, all patients were divided into two subgroups. The first subgroup included 27 patients with coronary heart disease and diabetes mellitus type 2 with monovascular lesions of coronary arteries...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480851/new-method-of-treatment-of-pyoinflammatory-soft-tissue-complications-in-patients-with-diabetes-mellitus
#18
S Karatieieva, I Plesh, O Yurkiv, S Semenenko, I Kozlovskaya
Our study evaluated the levels of peroxide oxidation of lipids, oxidative modification of proteins, antioxidant protection and dynamic changes in markers of toxicity in patients with diabetes mellitus and purulent-inflammatory complications. In total, 124 patients were enrolled in the study and were divided into two groups according the treatment methods. Study group consisted of 53 patients, who received intravenously ozonized saline in addition to conservative treatment. The control group consisted of 71 patients who received only conventional therapy...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480850/the-role-of-primary-health-care-in-assessing-and-preventing-health-risk-factors-of-adolescents-in-georgia
#19
N Mirzikashvili, L Baramidze
The goal of this study was to evaluate health risk factors, specifically tobacco use and alcohol consumption among adolescents and primary health care role in health promotions activities. The quantitative survey was conducted among 11-19 years old adolescents. Overall, 1000 young people were interviewed across Georgia using a standard questionnaire in 2014. The survey sampling methodology was multi-stage probability sampling. All information was analyzed in SPSS 21 version. According to survey results 32.1% (n=256) respondents consume tobacco; 90...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480849/impact-of-internet-gambling-on-mental-and-psychological-health-of-children-of-various-ages
#20
M Khundadze, N Geladze, N Kapanadze
The aim of the study was to assess the impact of internet gambling on children's mental and physical health and find correlation between the age, duration of internet use and type of comorbidity associated with internet gambling. The study assessed 50 patients with internet gambling (35 boys, 15 girls) from 2013-2016 y. The age range was 3-15 years. 15 patients were from 3-7 y of age, 20 patients from 7-12 y and 15 - from 12-15 y of age. The core problem common for all patients were internet overuse by computer games, mobile device and other gadgets...
March 2017: Georgian Medical News
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