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Georgian Medical News

L Kakiashvili, M Tsagareli, D Mjavanadze, I Kvachadze
Pain is almost synonymous with sport. For many athletes, pain is a normal everyday experience and success is often achieved in spite of pain. However, pain can restrict the ability to concentrate on performance and take away the opportunity to compete. It can even end sporting careers. Therefore, the relationship between pain and sport is filled with challenges for athletes. One consequence and response that sport researchers have focused on is the pain associated with injury. Sport medicine professionals have directed the major part of their research and rehabilitation attention towards the physical recovery, but psychological factors are also very important for injured athletes...
October 2016: Georgian Medical News
T Gabunia, S Turabelidze, M Machavariani, M Enukidze, Nina V Kipiani, G Sharashenidze, T Sanikidze
The purpose of our study was to establish the laser effects on the epithelial tissue and immune metabolism. The research was conducted on human leukemic mature T cells (Jurkat cells) (DSMZ-Deutshe Sammulung von Mikroorganismen und Zellkulturen (Germany)) and MDCK cell line (Lugar Laboratory, Tbilisi, Georgia). Cells were radiated by Laser device "ОПТОДАН"- АЛСТ-01 (power 5 W) 3 -7 days (4 minutes per day). With the aim to model oxidative stress-induced apoptosis, 30% hydrogen peroxide (H2O2) (Sigma) is added to Jurkat cells, in doses 25 and 50μM [4, 5]; and MDCK cells, in doses 400 and 800 μM [19] added to incubation suspension with subsequent incubation for 24, 48 and 72 hrs...
October 2016: Georgian Medical News
S Mataradze, T Naneishvili, M Sephashvili, D Mikeladze, M Dashniani
The present study investigated spatial working memory assessed in spontaneous alternation (SA) task and hippocampal glutamate and GABA release prior to, during, and after SA test in sham-operated and electrolytic medial septal (MS) lesioned rats. Also, have been investigated the effects of MS lesion on KCl-stimulated release of glutamate and GABA in the hippocampus. Behavioral study showed that electrolytic lesion of MS significantly impaired SA performance. Although both groups of animals had an insignificant rise in their respective hippocampal glutamate efflux during the SA, the rise of MS lesioned animals was blunted when compared with control animals...
October 2016: Georgian Medical News
N Avazashvili, P Imnadze, I Mchedlishvili, Kh Gachechiladze
In this article, there are given data of study for antibiotic sensitivity/resistance of gram-positive and gram-negative representatives of different microbial species, isolated from patients after primary hip replacement and osteosynthesis of long bones, which had post operative infectious complications, and also isolated from samples of traumatology department environment. Identification of sensitivity/resistance to antibiotics was performed with use of two methods - disc diffusion and serial dilution on solid nutrient media...
October 2016: Georgian Medical News
N Nachkebia, M Shavgulidze, M Babilodze, E Chkhartishvili, N Rogava
Present study investigated possible differences in the learning and memory of declarative memory task in rats selected according to the differences in immobilization response that is in high immobilization "depressive" and low immobilization "non-depressive" rats. Understanding the character of learning and memory disturbances in basal conditions of animal models of depression is still very topical for more intimate definition of the pathophysiology of major depressive disorder and appropriate searching the ways of its correction...
October 2016: Georgian Medical News
L Kruashvili, M Demurishvili, M Burjanadze, M Dashniani, G Beselia
In the present study we evaluated effects of selective cholinergic or GABAergic lesions of the nucleus basalis magnocellularis (NBM) using immunotxins 192 IgG-saporin and GAT1-SAP on place and response learning in plus-shaped maze. In current behavioral paradigm rats learned food-rewarded mazes that were efficiently learned using either place or turning strategies. A histological evaluation indicated that 192 IgG-saporin lesions specifically depleted cholinergic neurons but did not result in noticeable damage to the GABAergic cells within NBM...
October 2016: Georgian Medical News
H Galstyan
The study of the health shaping environment of students is one of the actual biomedical tasks, it is also the scientific founding for conducting health-preventive and health-preserving measures. Despite the importance of the proposed problem, this study is a pioneering attempt in Nagorno Karabakh. The objective of the work is the scientific grounding of regional peculiarities and the contemporary level of health shaping environment of students on the basis of population monitoring system. The results of the study prove that the studied health criteria are within limits of physiological norm...
October 2016: Georgian Medical News
G Baisunova, B Turdaliyeva, K Tulebayev, D Zagulova
Aim of the study was to explore the relationships between health literacy (HL) and financial wellbeing in residents of Almaty oblast (region). The survey was conducted among 826 residents of Almaty region aged 18 y.o. Over 56.5% were female residents. To estimate health literacy, self assessed health, financial wellbeing and attitude towards health /work -questionnaire HLS-EU-Q was used. The results confirmed a significant relationship between financial wellbeing, health literacy and health outcomes residents of Almaty region...
October 2016: Georgian Medical News
C Sahin, C Varim, M Uyanık
The aim of this study was to assess the neutrophil to lymphocyte ratio (NLR) as an inflammation marker in patients with chronic tonsillitis and to compare the NLR values to other inflammation markers, such as antistreptolysin-O (ASO), C-Reactive Protein (CRP) and erythrocyte sedimentation rate (ESR). Thirty patients aged between 4 and 15 y.o. who had undergone surgery for chronic tonsillitis were included in this retrospective study. Blood samples including haemogram, ASO, CRP and ESR were taken from the patients the day before and one month after the surgery and were analysed retrospectively...
October 2016: Georgian Medical News
S Karatieieva, O Yurkiv, S Semenenko, I Kozlovskaya, S Yakobchuk
Studying the effect of ozone therapy on the course of pyoinflammatory processes with diabetes mellitus in the experiment, conducted on 30 white 24-30 month rats, weight 300-450 gr with purulent-inflammatory processes, it was found out that diabetes, which was simulated by subcutaneous injection of alloxan, causes mosaic disturbances of hemostasis system in the presence of pyoinflammatory processes. Complicated changes in blood condition were also detected against the background of diabetes mellitus: chronometric hypocoagulation on the intrinsic pathway of blood coagulation in association with chronometric hypercoagulation by the external thrombinogenesis mechanism and fibrinogenesis depression against the background of hypofibrinogenaemia...
October 2016: Georgian Medical News
O Abrahamovych, U Abrahamovych, A Kushyna, S Guta, M Farmaha
The article studies the dependence of indicators of daily monitoring of heart rate on the pathological process activity in patients with systemic lupus erythematosus. As a result of examination of 83 patients (71 women and 12 men aged 17 - 68) with the first, second and third levels of disease activity (first, second and third group respectively) it was found that: 1) the average, maximum and minimum heart rate in patients with systemic lupus erythematosus during the day is significantly higher than the comparable figures in healthy individuals and the dependence of the increase of heart rate on the progress of disease activity was demonstrated by the results of the evaluation of minimum heart rate and in patients with the third degree of disease activity; 2) the vast majority of indicators of heart rate in patients with systemic lupus erythematosus, evaluated separately in active and passive periods of the day, were above the comparable indicators in healthy individuals and higher in the active period compared to the passive, with statistical significance of differences in average and maximum heart rate; 3) the regularity of an increase of average, maximum and minimum heart rate with the increase of activity of systemic lupus erythematosus is characteristic of patients with high activity of the disease (third degree) and is more pronounced in passive (night) period...
October 2016: Georgian Medical News
L Rasputina, V Rasputin, M Ovcharuk, O Serhiichuk, A Broniuk
The purpose of our work was to determine a prevalence of depression and its distribution by grades in patients with a coronary heart disease, namely - with the myocardial infarction. The study involved 125 patients of average age 64.2±4.7 years, treated at cardiology department for myocardial infarction. The first stage was a depression screening using PHQ - 2 questionnaire. In case of positive answer to at least one question, we assessed the severity of depression using a PHQ-9 tool. We established, that PHQ-2 questionnaire questions for screening depressive disorders were positively answered by 80 patients (64...
October 2016: Georgian Medical News
D Rekalov
The aim of the research was to study biomarkers of osteochondral lesions on early stages of rheumatoid arthritis (RA). The data showed the prognostic value of indicators of the erosive and destructive changes of joints in early and in the advanced stage of RA. Indicators that determine how directly, inflammatory process activity and markers associated with the speed and staging damage of articular surfaces is analyzed. That can adequately justify individualized clinical strategy in patients with early RA.
October 2016: Georgian Medical News
E Rukhadze, N Bregvadze-Tabagari, L Tvildiani
The objective the study was to assess the association between echocardiographic parameters and established cardiovascular risk factors in adults without clinical manifestation of heart failure (HF). A cross-sectional study was conducted between (September 2008 - December 2010) Consecutive sample of 177 participants were enrolled in the study. We performed routine Transthoracic Echocardiography and evaluated several well established cardiovascular risk factors. The data was analyzed using SPSS, version 16. LA was significantly correlated with age (r 0...
October 2016: Georgian Medical News
K Kankava, E Kvaratskhelia, E Abzianidze
The role of epigenetics in tumor development and progression is actively being studied. The aim of our current pilot study is to analyze correlation of changes in the levels of methyltransferases in nuclear extracts of blood cells with some morphological and phenotypic characteristics of breast cancer. The levels of DNMT1, DNMT3a and H3K4 methyltransferase were measured. The results showed that the level of DNMT1 was highest in the control group but correlation with the tumor grade was just moderate. DNMT3a was found in highest level in Grade III cancer group, followed by Grade II and Grade I groups...
October 2016: Georgian Medical News
N Zhelezniakova
Objective -to identify mechanisms of osteopenic syndrome implementation in patients with comorbid course of COPD and chronic pancreatitis (CP). 51 patients with comorbidity of CP and COPD (main group), 47 - with isolated COPD (compared group) have been examined. Assessment of excretory function of the pancreas was performed by determination of elastase-1 in the feces. Concentrations of interleukin-1β, interleukin-6 and tumor necrosis factor-α were determined by ELISA. It has been found out that patients with comorbid pathology are characterized by the significant decrease of bone mineral density than in the compared group...
October 2016: Georgian Medical News
N Lomidze, M Gotua
Molecular-based allergy (MA) diagnostics is a novel approach used to map the allergen sensitization of a patient at a molecular level, using purified natural or recombinant allergen components instead of allergen extracts. The aim of our study was to: 1) investigate sensitization patterns to food and inhalant allergen components in different age groups of Georgian allergic patients 2) evaluate patient's potential risk of systemic reaction and manage dietary modifications. 3) Study food and inhalant components in different age groups in correlation with clinical manifestations of allergic disease...
October 2016: Georgian Medical News
V Zlatkina
The current pace of growth in body weight and complications in children and patients of the young age is a serious problem. The aim of the work was to determine the vaspin concentration depending on the presence of obesity in patients of the young age with arterial hypertension and the study of its relationship with carbohydrate metabolism. The progression of obesity and hypertension is accompanied by increase of insulin resistance. The increase in the blood concentration of vaspin is observed in patients with hypertension and normal body weight...
October 2016: Georgian Medical News
R Naghiyev, S Imamverdiyev, O Sanli
Aim - retrospective comparative analysis of results of laparoscopic partial nephrectomy (LPN) depending on the type of access and the size of the tumor. The study included 170 patients undergoing LPN during the period from 2010 to 2015 years. Among the patients was 108 males (63.5%) and 62 women (36.5%) ranging in age from 17 to 80 years (average age 56,6±0.9 years). Depending on the type of access and the size of the tumor patients divided into 4 subgroups-154 patients who performed transperitoneal LRP, 16 patients undergoing retroperitoneal partial nephrectomy, 117 patients with tumor less than 4 cm and 53 patients with tumor more than 4 cm...
October 2016: Georgian Medical News
A Minasyan, R Sargsyan
The aim of this study is to improve the results of surgical treatment of acute bowel obstruction caused by rectal cancer and to reduce the period of full recovery of patients. The presented research included 73 patients (study group) with rectal cancer who underwent emergent anterior resection of rectum with loop ileostomy and intra-operative decompression of colon. Patients of this group were compared to a group of 68 patients (control group) with the same diagnosis who underwent Hartmann's procedure. There was no essential difference between the two groups in the quantity of postoperative complications...
October 2016: Georgian Medical News
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