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Georgian Medical News

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https://www.readbyqxmd.com/read/28726668/formulation-and-technology-development-of-herbal-phenolic-biopolymer-containing-films-for-burn-treatment
#1
S Gokadze, V Barbakadze, K Mulkijanyan, A Bakuridze, L Bakuridze
Application of phytofilms based on biosolublepolymers is considered as a prospectivemethod for burn treatment . Herbal remedies contain biologically active substances, that are relatively less toxic, do not cause skin irritation or allergic reactions and, importantly, affectstrains of the microorganisms and viruses resistant to antibiotics and synthetic drugs. Nowadays, the advantages are given to such burn healing drugs, which along with high specific efficacy, have analgesic, anti-inflammatory and antimicrobial effects, and don't irritate the tissues...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726667/clinical-and-genetic-peculiarities-of-vascular-manifestations-of-antiphospholipid-syndrome-case-report
#2
D Vasylyev, L Chernobay, O Vasylieva, M Oliinyk, M Vashuk
Pathogenetic mechanisms of the development of antiphospholipid syndrome (APS) are considered in the article, which is the basis for the development of clinical manifestations and laboratory markers of APS. The modern literature data are analyzed, according to which the presence of antiphospholipid antibodies is a hypercoagulable background, and the formation of thrombi occurs under the influence of other allowing procoagulation factors. The classification of the main types of hereditary thrombophilia is given, which is the primary disorder, against the background of which an autoimmune thrombosis APS develops...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726666/-pathomorphological-changes-under-latent-mastoiditis
#3
Kh Chitadze, T Jorbenadze, M Adamia
In our opinion it is caused by incomplete awareness of the distribution of pathological process and the character of morphological changes in the patients. In this regard, we studied structural changes in the soft and bone tissue taken from various cavities of the middle ear system. Operating material was formed in paraffin after the fixation and proper processing. We proceed with decalcification of bone tissues in 15-20% nitric acid. We painted 5-6 mm thick peels prepared on the rotating microtome with hematoxylin and eosin...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726665/-about-the-role-of-digestive-tract-decompression-in-patients-with-acute-bowel-obstruction-mistakes-complications-and-their-prevention
#4
V Benedykt
The purpose of the work is improvement in treatment of patients with acute small bowel obstruction by justification for gastrointestinal decompression and different methods of small intestine intubation for effective evacuation of itscontents. We conducted morphological and morphometric study of the small intestine in 53 white rats. It was established that acute small bowel obstruction causes expansion of all parts of small bowel microvasculature with significant lesions of venous structures. We revealed thinning of intestinal muscular layer 2...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726664/expanded-phenotype-of-tmem67-gene-mutation-case-report
#5
T Tkemaladze, G Melikishvili, V Kherkheulidze, A Melikishvili, T Davitaia
Human ciliopathies are a class of multi-organ genetic disorders caused by defects of proteins expressed at the primary cilium, an organelle present on the cell surface of almost all cell types. Thus far, dozens of causative genes for ciliopathies have been identified and many of them are known to cause allelic disease. Of particular interest is the TMEM67 gene, encoding the transmembrane protein meckelin. The involvement of the mutant TMEM67 gene is known to be associated with a broad range of clinical presentations, namely Joubert syndrome 6 (JBTS6), nephronophthisis 11 (NPHP11), Bardet-Biedel syndrome (BBS), COACH syndrome, and lethal Meckel syndrome type 3 (MKS3)...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726663/-peculiarities-of-community-acquired-pneumonia-in-children-with-neurological-pathology
#6
O Zubarenko, G Kopiyka, T Kravchenko, L Koval, K Gurienko
Neurological disorders in children highly affect the course of pneumonia, its outcome and the development of possible complications. The aim of the study was to reveal clinical and paraclinical features of community-acquired pneumonia in younger children with neurologic pathology infantile cerebral palsy. Under observation were 37 children with community-acquired pneumonia aged 1 to 3 years that suffered from spastic forms of infantile cerebral palsy. The comparison group consisted of 30 children with community-acquired pneumonia without any concomitant neurological pathology...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726662/cytokines-as-the-predictors-of-severe-mycoplasma-pneumoniae-pneumonia-in-children-review
#7
I Chkhaidze, N Kapanadze
In spite of many attempts to differentiate bacterial from viral disease and predict severity and outcome, the etiologic diagnosis of paediatric community acquired pneumonia and the estimation of potential outcomes remain unsolved problems in most cases. Mycoplasma pneumoniae is one of the major pathogens causing CAP in children. Although MP infection was traditionally thought to be a self-limited process, more and more severe cases even fatal cases of MP infections were reported in recent years. So it is essential for pediatricians to recognize severe or refractory or severe MP early, treat it promptly and prevent the progress of the disease...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726661/-heart-rate-variability-in-children-with-false-chords-in-the-left-cardiac-ventricular
#8
A Kuleshov
We examined 64 children with false tendons in the left cardiac ventricular. The research included evaluation of time and frequency domain parameters of the heart rhythm with cardiointervalography. The parameter changes were noted. Thus, sympathetic vegetative system (VS) part prevalence was present in boys and characterized by decreasing of SDNN when compared with control data (85,4±5,8 и 158,2 ±25,6, р<0,05). rMSSD and PNN50%, which are responsible for parasympathetic VS part have the tendency to increasing in girls...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726660/pemetrexed-induced-pseudocellulitis-a-rare-cutaneous-adverse-reaction-to-multi-targeted-antifolate-therapy
#9
U Hansel G Zschuppe E Tchernev G Wollina
Pemetrexed is a multi-targeted folate antagonists approved for non-small cell lung cancer and other malignancies. Adverse cutaneous reactions have been reported in up to 1/3 of patients treated. A rare cutaneous adverse reaction is pseudocellulitis. We report about a 62-year-old male patient treated with a combination of cisplatin and pemetrexed for non-small cell lung cancer stage IV who developed about 4 months after initiation of treatment painful, non-febrile erythematous lesions on feet and lower legs...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726659/factors-affecting-survival-of-women-diagnosed-with-breast-cancer-in-georgia
#10
N Vashakidze, N Mebonia, M Kereselidze, S Zhizhilashvili
Breast cancer is the most frequently diagnosed cancer in women worldwide with nearly 2.4 million new cases diagnosed in 2015, In Georgia survival from breast cancer is lower than in many developing countries. The goal of the study was to identify predictors for low survival of disease in the country. Data from population-based cancer registry was used in order to estimate 1-year and 5-years relative survival rates for breast cancer. To identify predictors for low survival time, was performed bivariate analysis...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726658/-optimization-of-diagnostics-of-exudative-pleuritis-of-unknown-origin
#11
B Bayramov
The article describes 143 cases of exudative pleuritis of unknown origin in patients who were diagnosed and treated with any minimally invasive surgical procedures: pleural puncture (PP), video-assisted thoracoscopy (VATS) with biopsy of the pleura. A different diagnostic methods (cytological, microbiological, histological) used in various diagnostic surgical procedures are analyzed in detail and calculated diagnostic sensitivity, specificity, and accuracy of each method. Based on the analysis of cytological, histological and microbiological studies in the performance of VATS concluded relatively high, comparable with the method of open pleural biopsy, diagnostic efficiency, the sensitivity of this method in the scheme of the diagnostic algorithm of EP of unknown origin...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726657/echocardiographic-characteristics-of-different-who-ish-cardiovascular-disease-risk-groups
#12
E Rukhadze, N Bregvadze-Tabagari, L Tvildiani
The objective of the study was to analyze association of echocardiographic TOD variables with the CVD risk groups defined by WHO/ISH. A cross-sectional study was conducted between (September 2008 - December 2010) Consecutive sample of 146 participants were enrolled in the study, 97 (66.4 %) women and (49) 33,6 % men, mean age. Study population was categorized in three groups according to WHO/ISH risk categories: Group 1 included population with risk less than 10% according to WHO/ISH, in Group 2 there were united two WHO/ISH risk categories (10-10...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726656/anxiety-levels-in-patients-with-paroxy-smal-supraventricular-tachycardia-in-relation-with-the-patient-demographics-type-of-supraventricular-tachycardia-and-their-personality-type
#13
G Papiashvili, N Tabagari-Bregvadze, J Brugada
The aim of the study was to evaluate the incidence of different personality types and state and trait anxiety levels in patients with paroxysmal supraventricular tachycardia and their association with patients age, gender and the mechanism of the paroxysmal SVT. 62 patients with documented paroxysmal supraventricular tachycardia who underwent endocardial eletrophysiological study and catheter ablation of the paroxysmal SVT were included in the study. The patients were asked to fill out the Myers-Brigss Type Indicator and State-Trait Anxiety Inventory questionnaires and the results were analyzed and correlated with the arrhythmia mechanism determined during electrophysiological study and catheter ablation procedure, and the patients' demographics (age and gender)...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726655/influence-of-beta-blockers-and-ivabradine-on-long-term-prognosis-of-patients-with-stable-angina
#14
T Ilashchuk, O Glubochenko, B Senyuk, N Bachuk-Ponich, I Lukashevich
The purpose of the study was to evaluate the influence of beta-blockers and ivabradine on long-term prognosis of patients with stable angina. 90 patients with stable angina that have been involved in present study along with nitrates, antiplatelet agents and statins received bisoprolol (Group I), carvedilol (Group II) and ivabradine (Group III). We analyzed the following indicators: patient adherence to treatment, cases of myocardial infarction and circulatory decompensation, which resulted in necessity of patient's hospitalization during the year of observation, calculating the probability of achieving a key prognostic endpoint by patient using the concept of the odds ratio and determination of important components in the progression of the disease...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726654/the-safety-and-efficacy-of-amiodarone-and-carvedilol-combination-in-treatment-of-patients-with-severe-cardiac-rhythm-disorders
#15
E Tsetskhladze, I Khintibidze
Different arrhythmias are cause of sudden death in many patients with heart failure. Amiodarone is usually used for prevent this arrhythmias, but it is not drug of choice for treatment the patients with heart failure. We retrospectively analyzed 142 patients with moderate and severe heart failure and history of myocardial infarction. These patients have received amiodarone, carvedilol or combination of these two medications together with standard therapy. In our retrospective analysis, the combination therapy with Amiodarone and Carvedilol had highly significant decrease arrhythmic death compare with carvedilol and amiodarone groups...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726653/retrospective-study-of-evaluation-of-patients-with-st-elevation-myocardial-infarction-and-intact-coronary-arteries-evaluation-of-treatment-approaches-outcome-and-prognosis
#16
E Tsetskhladze, I Khintibidze
Myocardial infarction with normal coronary arteries is a well known pathology. It may or may not be associated with left ventricle wall motion abnormalities. Data was reviewed retrospectively for patients with ST elevation myocardial infarction who underwent cardiac catheterization. From the total number of patients evaluated 10.3% (17) patients had Myocardial Infarction with normal coronary arteries. Females were more likely to present with MINCA then males. Coronary flow was normal in 11 from 17 patients with MINCA...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726652/investigation-of-bone-mineralization-in-patients-with-coronary-heart-disease-complicated-by-chronic-heart-failure-stage-ii-a
#17
I Krynytska, M Marushchak, T Zaets, I Savchenko, H Habor
The majority of the studies have shown that individuals with cardiovascular diseases have a higher risk of experiencing bone loss and thus greater predisposition to risk of fracture. On the other hand there is growing evidence that individuals with low bone mass have higher mortality for cardiovascular events compared to patients with cardiovascular disease with normal bone mass. This research aims to investigate bone mineralization in patients with coronary heart disease complicated by stage II-A chronic heart failure...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726651/factors-associated-with-post-stroke-fatigue-within-the-first-3-month-after-stroke
#18
I Delva, N Lytvynenko, M Delva
Aim - identify socio-demographic, personal and psychological factors associated with certain post-stroke fatigue (PSF) domains within first 3 months after stroke. There were examined patients consequently in definite time points after ischemic or hemorrhagic strokes: at hospital stay (234 patients), in 1 month (203 patients) and in 3 months (176 patients). Global PSF and certain PSF domains were measured by multidimensional fatigue inventory-20 (MFI-20) scale. In multivariate logistic regression analysis the majority of variables (gender, marital status, education level, smoking status, level of alcohol consumption, apathetic impairments, arterial hypertension, atrial fibrillation, ischemic heart disease, diabetes mellitus, body mass index, waist circumference) were not significantly associated with any PSF domain risk at any time point after stroke...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726650/-modified-system-of-thromboprophylaxis-in-patients-with-surgical-profile
#19
O Kolotylo, I Venher, S Kostiv, A Iftodiy
The aim of the study was to reduce the incidence of postoperative thrombosis in the veins of the inferior vena cava basin under planned surgical interventions by using a modified thromboprophylaxis method. Two groups of patients were studied in a total of 698 patients who underwent a risk assessment of postoperative venous thromboembolism (PVTE) using the J. Caprini scale (2012). According to the patients indicated in determining the degree of risk of HTHP development according to the J. Caprini scale, the level of surgical stress was simultaneously determined...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726649/lipoprotein-associated-phospholipase-a2-as-a-marker-of-vulnerable-atherosclerotic-plaque-in-patients-with-internal-carotid-artery-stenosis
#20
P Štefanič, I Kopolovets, Z Hertelyová, Š Tóth, M Frankovičová
The aim of this study was to compare the concentration of inflammatory vascular markers and morphological structure of atherosclerotic plaque in symptomatic and asymptomatic patients with the stenosis of internal carotid artery (ICA). The research was carried out in 70 patients with hemodynamically significant stenosis of ICA out of which 40 (57%) were asymptomatic patients and 30 (43%) were symptomatic patients, of which 20 patients (66%) have had a stroke, or transient ischemic attack (TIA), 10 patients (33%)...
June 2017: Georgian Medical News
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