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Georgian Medical News

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https://www.readbyqxmd.com/read/28009324/the-impact-of-ultraviolet-irradiation-on-morpho-functional-state-of-skin-in-guinea-pigs
#1
S Myronchenko, O Naumova, T Zvyagintseva
The purpose of this study was to assess the impact of ultraviolet irradiation (UV) on morphological and functional condition of the skin in guinea pigs. The study involved 30 albino guinea pigs weighing 400-500 g subjected to local exposure to UV irradiation. Control group consisted of intact guinea pigs. Histological studies of the skin were carried out at different stages of the trial (2 hours, 4 hours, 3 days, 8 days following the exposure). Microscopic examination showed morphological signs of acute inflammation in the skin of animals within the first three days following the exposure to UV irradiation...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009323/-to-a-question-of-treining-of-the-neonatologists-in-residency
#2
T Klimenko, E Serdceva, T Sandulak, A Zakrevskyy, O Karapetyan
: In recent years, the world and in Ukraine neonatology evolved into high-tech and quickly progressive section of the medicine, therefore preparation of experts is very important problem. Residency is the form of specialization of doctors on corresponding clinical chairs for reception of high qualifications of neonatology for possibility of competent rendering of competent and highly specialized medical care to newborns in hospitals of 3rd level. Term of training in residency is 2 years...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009322/predicting-of-risks-of-groundwater-and-surface-water-pollution-with-different-classes-of-herbicides-in-soil-in-eastern-europe-climate-conditions
#3
M Korshun, O Dema, O Kucherenko, O Korshun, S Garkavyi, I Pelio, A Antonenko, N Velikaia
Application of pesticides in modern agriculture is a powerful permanent risk factor for public health and the natural environment. The aim of the study was a comparative hygienic assessment of the danger of contamination of ground and surface water sources with most widely used herbicides of different chemical classes (sulfonylureas, imidazolinones, pirimidinilkarboksilovye compounds semicarbazones). Field hygienic experiments for studying of the residues dynamics of studied herbicides concentration in agrocenosis objects were made by us in different types of soils: chernozem, sod-podzolic, podzolized forest...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009321/-comparative-analysis-of-antibacterial-effect-of-phytoantibiotics-and-antibiotics
#4
L Akhvlediani, T Koiava, L Lomtadze, M Joxadze, L Msxiladze, D Berashvili, A Bakuridze
The objective of this study was to determine the antibacterial activity of individual medicines and containing sum of the phyto-extracts against the bacteria causing nosocomial infections in compare to antibiotics. In the investigation were involved four strains of gram-negative bacteria Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus and Acinetobacter spp. Each object was investigated on antibiotic resistance using Kirby-Bauer diffusion method on 22 types of antibiotics. The objects of the study were: Sanguinarine, Chelerythrine and Berberine hydrochloride (of lab quality); essential oils and aromatic waters of Eucalyptus, Salvia and Lavanda...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009320/-the-features-of-pharmacokinetics-antibiotic-ceftriaxone-with-intravenous-way-that-are-deposited-in-autologous-erythrocytes-and-leukocytes-of-rabbit
#5
Z Yussifov, S Lokhvitskii, A Gulyaev
In the experiment on 18 rabbits Сeftriaxone pharmacokinetics after intravenous injection of the medication deposited in autologous erythrocytes and leukocytes were studied. The features of the pharmacokinetics when administered Сeftriaxone in erythrocytes ghost and leukocytes as compared to traditional intravenous drug administration have been determined.It is discussed the possibility of antibiotics transport in the surgical site of infection via cellular carriers in the article. We do the comparative analysis of the main pharmacokinetic parameters of Ceftriaxone in experimental conditions of leukocyte, erythrocyte transport and intravenous way...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009319/-ultrasound-monitoring-of-central-and-cerebral-hemodynamics-during-the-treatment-of-arterial-hypotension-in-preterm-infants
#6
A Zakrevskyy, O Karapetyan, V Agashkov, K Kosenko
The purpose of the study was to evaluate and identify patterns of changes in central and cerebral hemodynamics in neonates with low and extremely low birth weight and birth asphyxia, in order to achieve the early diagnosis of disorders of the central hemodynamics and autoregulation of cerebral blood flow, for timely fluid correction and inotropic therapy. Observation data on 44 preterm infants who were treated at the Kharkiv City Perinatal Centre and Regional Children's Clinical Hospital №1 of Kharkiv has been analyzed...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009318/indicators-of-phagocytic-component-and-secretory-iga-in-children-with-bronchial-asthma-secondary-to-undifferentiated-connective-tissue-dysplasia
#7
V Semianchuk, L Haridzhuk, O Bobrykovych
Its aim is to improve the diagnostics and treatment of Bronchial Asthma. There were examined 93 children with bronchial asthma at the age of 6-10 years. All patients were diagnosed with partially controlled or uncontrolled clinical course of bronchial asthma and manifestations of undifferentiated connective tissue dysplasia. The control group included 21 practically healthy children of the same age. The diagnosis of bronchial asthma was made, and the clinical course was determined in accordance with the criteria approved by the Order of Ministry of Health of Ukraine of October 08, 2013 No 868 "Unified clinical protocol of primary, secondary (specialized) medical care "Bronchial Asthma in Children" and GINA criteria (updated in 2015)...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009317/-evaluation-of-the-realtionship-of-different-pathogenic-factors-and-arrhythmias-in-patients-with-pulmonary-tuberculosis-and-diabetes
#8
Z Kurbanova, A Bahshaliyev, R Bayramov, J Ismailzada
Definition of the most important factors and their combination, causing the disturbances of heart rhythm in patients with the pulmonary tuberculosis and diabetes, now attracts more and more attention. For this purpose, extensively used the capabilities of multifactorial analysis, which allowed to evaluate the distribution of the pathological factors and their interaction with each other. The objects of the study were complex examination the data of 90 patients with pulmonary tuberculosis and diabetes (insulin-dependent diabetes-27, non-insulin- dependent diabetes-63)...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009316/-efficacy-of-combined-use-of-antioxidative-and-phototherapy-in-the-treatment-of-vitiligo
#9
N I Tsiskarishvili, A Katsitadze, N V Tsiskarishvili, Ts Tsiskarishvili, L Chitanava
Despite of numerous investigations, carried out practically in all countries of the world for the study of vitiligo and the search for its new effective therapies, pathogenic mechanisms of vitiligo are still poorly understood, and the proposed treatments are not perfect. One of the most accepted theories of the pathogenesis of vitiligo is an oxidative stress theory, according to which a series of biochemical anomalies cause oxidative stress, leading to accumulation of melanocytotoxic substances and inhibition of natural processes of detoxification with subsequent destruction of melanocytes in vitiligo focus...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009315/differences-in-ecg-characteristics-and-co-morbidities-among-patients-who-underwent-elective-surgical-repair
#10
I Botchorishvili, N Sharashidze, N Pargalava, Z Pagava, G Saatashvili
The aim of the study was to assess differences in ECG features and prevalence of comorbidies between two groups of patiens: with Abdominal Aortic Aneurism (AAA) and Aorto-Iliac Occlusive Desieses-Lerish Syndrome (LS). Data was collected for all consecutive adult patients who underwent elective surgical repair of AAA (fusiform aneurysm) or LS at "The Center of Vascular and Heart Diseases" (Tbilisi, Georgia) between 2010 and 2014. We studied a prevalence of Arterial Hypertension (AHT); Diabetes mellitus (DM); Renal Failure (RF),Peripheral Artery Disease (PAD), Coronary Artery Disease (CAD) and rate of coronary revascularization in these patients; We also, investigate some of the electrocariographic characteristics: Corrected QT interval(QTC),QT dispersion(QTD)...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009314/hurtle-cells-immunohistochemical-activities-in-hashimoto-thyroiditis-parenchyma
#11
Z Tsagareli, T Kvachadze, E Melikadze, L Metreveli, E Nikobadze, L Gogiashvili
The present study was designed to evaluate the participation and utility of Hǘrtle cells morphological requirment and transformation under Hashimoto autoimmune thyroiditis versus Riedel´s struma. Several markers have been evaluated to detect induced activities of Hǘrtle cells. Study subject - specimens (tissue fragments) collected from TG surgery (thyroidectomy) for mollecular (receptor) diagnosis of Hǘrtle cells activities using routine histological and immunohistochemical samples. 89 cases were selected in Hashimoto thyroiditis diagnosis with Hǘrtle cells history (adenoma and adenomatous grouth of oncocytes)...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009313/character-and-frequency-of-the-variations-of-co-and-polymorbid-syntropic-extrahepatic-lesions-and-their-dependence-on-the-hepatopulmonary-syndrome-severity-degree-in-cirrhotic-patients
#12
O Abrahamovych, M Abrahamovych, S Tolopko, O Fayura, M Ferko
In this study, we comprehensively examined 93 patients with liver cirrhosis, selected in a randomized manner, with the preliminary stratification by the presence of hepatopulmonary syndrome with the aim to study the nature and frequency of extrahepatic syntropic lesions of organs and systems and their dependence on the severity of lung injury that is necessary for the appointment of the most effective individualized comprehensive treatment. The results of our calculations showed that with the increasing of the hepatopulmonary syndromeseverity degree, the nature and the frequency of the syntropic co- and polymorbid functional and organic extrahepatic lesions of the organs and body systems was significantly (p<0...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009312/changes-in-tooth-hard-tissue-minerali-zation-and-blood-rheology-in-healthy-adolescents-and-those-with-thyroid-dysfunction
#13
S Beriashvili, M Nikolaishvili, M Mantskava, N Momtsemlidze, K Franchuk
Thyroid dysfunction causes spreading and development of caries in the teeth and changes in periodontal tissues. In addition, it causes changes in peripheral blood flow and mineralization, local transcapillary metabolism causes changes in blood rheology. There are only few works in this direction and, therefore, the purpose of our research was to find out how the mineralization and the rheological properties of blood are changed in lesion of periodontal tissue on a background of thyroid dysfunction. Accordingly, the stomatological study was conducted in 75 adolescents aged 12-18 years by the standard method, recommended by the World Health Organization...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009311/-malignant-tumors-in-ovarian-mature-cystic-teratomas-intraoperative-diagnostic-basis
#14
A Khachatryan
Extremely rare ovarian primary tumors formed in a mature cystic teratomaare described in the literature. This research work studies the frequency of malignant mature cystic teratoma, as well as their clinical and morphological features and necessity of intraoperative histological examination of all teratomas. Cases histories of 56 patients, suffering from ovarian mature cystic teratomahave been studied in MC Shengavit in the period of 2003 - 2015. Among them 4 patients with the somatic malignancies were identified...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009310/-the-early-diagnostics-of-multiple-primary-tumors-of-male-urogenital-tract-review-of-clinical-cases
#15
A Khachatryan
Multiple primary tumors (MPT) or polyneoplasias significance is very important. MTP are met rarely in male urogenital system; only single cases are described in the literature. Nevertheless, during the last years there has been an increase of their frequency. So, in order to understand are urogenital MPT popular in men, what is the connection between their appearance and whether there is a trend of increase or not, we have decided to investigate the cases histories of 272 oncourological patients between 18-84 years old have been studied in the period of 2013 - 2015...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009309/-modern-approaches-to-correction-of-hypernatremia-in-neurosurgical-patients
#16
D Vassilyev
The article presents the analysis of the intensive therapy through the correction of persistent hypernatremia in neurosurgical patients after removal of brain tumors. The aim of this work was to evaluate the effectiveness of Sterofundin in the framework of complex therapy of hypernatremia in neurosurgical patients after removal of brain tumors. We analyzed the dynamics of the concentrations of sodium, potassium, chorus of the plasma, anion gap and buffer bases in the postoperative period of these patients. For obtaining reliable results, the patients were divided into groups according to the nature of the treatment: Sterofundin and symptomatic correction of hypotonic solution of sodium chloride, saluretic and Verospiron respectively...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009308/-twin-to-twin-transfusion-syndrome-the-possibility-of-latent-flow-case-report
#17
E Kamyshanskiy, O Kostyleva, S Musabekova, M Tussupbekova, I Kopobaeva
The early diagnosis of the Twin-To-Twin transfusion syndrome (TTTS) carries benefits of the better survivor for the fetus-donor; but at the same time there are obvious practical impediments to diagnose the condition earlier in the course of a pregnancy. That's why this particular problem in practical medicine requires in depth investigation to clarify casual factors, and specify tactical approach to the prospective patients which in turn will lead to prevention of the fetal death and damage and improvement of fetal survivor in any form of TTTS...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/27845297/pain-perception-in-athletes-a-brief-review
#18
L Kakiashvili, M Tsagareli, D Mjavanadze, I Kvachadze
Pain is almost synonymous with sport. For many athletes, pain is a normal everyday experience and success is often achieved in spite of pain. However, pain can restrict the ability to concentrate on performance and take away the opportunity to compete. It can even end sporting careers. Therefore, the relationship between pain and sport is filled with challenges for athletes. One consequence and response that sport researchers have focused on is the pain associated with injury. Sport medicine professionals have directed the major part of their research and rehabilitation attention towards the physical recovery, but psychological factors are also very important for injured athletes...
October 2016: Georgian Medical News
https://www.readbyqxmd.com/read/27845296/impact-of-laser-therapy-on-the-proliferation-of-various-cultured-cells
#19
T Gabunia, S Turabelidze, M Machavariani, M Enukidze, Nina V Kipiani, G Sharashenidze, T Sanikidze
The purpose of our study was to establish the laser effects on the epithelial tissue and immune metabolism. The research was conducted on human leukemic mature T cells (Jurkat cells) (DSMZ-Deutshe Sammulung von Mikroorganismen und Zellkulturen (Germany)) and MDCK cell line (Lugar Laboratory, Tbilisi, Georgia). Cells were radiated by Laser device "ОПТОДАН"- АЛСТ-01 (power 5 W) 3 -7 days (4 minutes per day). With the aim to model oxidative stress-induced apoptosis, 30% hydrogen peroxide (H2O2) (Sigma) is added to Jurkat cells, in doses 25 and 50μM [4, 5]; and MDCK cells, in doses 400 and 800 μM [19] added to incubation suspension with subsequent incubation for 24, 48 and 72 hrs...
October 2016: Georgian Medical News
https://www.readbyqxmd.com/read/27845295/effects-of-medial-septal-lesion-on-hippocampal-extracellular-glutamate-and-gaba-levels-during-spatial-alternation-testing
#20
S Mataradze, T Naneishvili, M Sephashvili, D Mikeladze, M Dashniani
The present study investigated spatial working memory assessed in spontaneous alternation (SA) task and hippocampal glutamate and GABA release prior to, during, and after SA test in sham-operated and electrolytic medial septal (MS) lesioned rats. Also, have been investigated the effects of MS lesion on KCl-stimulated release of glutamate and GABA in the hippocampus. Behavioral study showed that electrolytic lesion of MS significantly impaired SA performance. Although both groups of animals had an insignificant rise in their respective hippocampal glutamate efflux during the SA, the rise of MS lesioned animals was blunted when compared with control animals...
October 2016: Georgian Medical News
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