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Georgian Medical News

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https://www.readbyqxmd.com/read/28132050/characteristics-of-rat-liver-exposed-to-nanoparticles-of-lead-compounds
#1
S Omelchuk, V Aleksijchuk, L Sokurenko, A Blagaia, S Prudchenko
In recent times, the lead becomes great importance in environmental pollution, including its nanoparticles. In the literature, there is little data on the changes in the liver after the exposure with lead nanoparticles. The purpose of this study was the identification and determination of macroscopic, microscopic, and biochemical changes of the structural elements of the rat's liver exposed to the action of lead compounds. The study was carried out on 60 male Wistar rats. The first and second groups of animals were intraperitoneally injected with colloidal solution of nanoparticles of Lead Sulfide size of 10 nm and 30 nm, and the third group was intraperitoneally injected with a solution of nitrate lead...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132049/-state-of-actual-food-adult-working-population
#2
S Bermagambetova, T Karimov, A Zinalieva, L Niazalina, A Nagmetova
The aim of our study was to investigate the actual nutritional status of industrial workers; chemical composition, nutritional and energetic value of the daily food intake of 299 workers in western Kazakhstan. We used a food frequency questionnaire with 24-hour recall to get comprehensive information on the daily diet. Computer calculation was conducted for assessing dietary intake. We carried out calculation of daily food intake, nutrient chemical composition and calorific value by means of a computer program "Diet" (Astana, 2011)...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132048/-donation-and-some-problems-of-defect-of-donor-s-blood
#3
K Tashtemirov, S Imangazinov, O Tashtemirova, V Egoshin
There was analyzed the prevalence of transfusion-transmissible infections among blood donors and its components by examining the monitoring of donor withdrawal to donations, the absolute structure of defect in the Blood Center of Pavlodar region (BCPR) of the Republic of Kazakhstan. The results quality was ensured by the compliance of the rules and conditions of the analytical and post analytical stages of the internal quality control. It is shown that the need to improve the work of a single donor's information center (EDITS), because Only 11...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132047/-the-phenotypic-manifestations-of-thalassemic-mutations-in-azerbaijan
#4
Ch Asadov, T Mammadova, E Abdulalimov, S Gafarova, G Aliyeva
The aim of this study was to investigate the phenotypic expression of the most common β-globin gene mutations - Codon 8 (-AA), IVS 1.6 and IVS 2.1 in heterozygous, homozygous and compound with HbS in Azerbaijan. In total, 137 homozygous and heterozygous β-thalassemia and S/β-thalassemia individuals were included to the study. Red blood cell count, hemoglobin, hematocrit and erythrocyte indices were studied. Furthermore, hemoglobin fractions were analyzed by electrophoresis on cellulose acetate films and high performance liquid chromatography...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132046/peculiarities-of-catenin-activity-in-the-embryonal-testicular-carcinoma
#5
S Potapov, R Sidorenko, D Galata, N Stratiy, V Gargin
The aim of the research was to study immunohistochemical peculiarities of catenin activity in the embryonal testicular carcinoma. Material is presented by 39 cases of embryonal testicular carcinoma for the period from 1993 to 2013. Macroscopic and histological investigation has been performed according to the WHO classification (2004). Immunohistochemical examination with monoclonal antibodies to Ki-67, β-catenin and E-cadherin were performed. Embryonal carcinoma is presented 12.38% of all testicular germ cell tumors in our observations with median age of patients 30...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132045/the-role-of-t-regulatory-and-th17-cells-in-the-pathogenesis-of-rheumatoid-arthritis-review
#6
N Kikodze, I Pantsulaia, T Chikovani
Chronic inflammation of joints of autoimmune origin - rheumatoid arthritis - develops due to deplorable coincidence of genetic, immune and environmental factors. Th17 cells are considered as the main effector cells in the pathogenesis of rheumatoid arthritis. Analysis of many reports clarify positive correlation between the frequencies of circulating Th17 cells, serum levels of IL-17A and IL-23, synovial IL-17 and disease activity. Autoreactive Th clone response is regulated by the certain population of suppressor cells - T regulatory cells (Tregs)...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132044/acquisition-and-consolidation-of-two-way-active-avoidance-in-the-high-immobilization-depressive-rats
#7
N Nachkebia, M Shavgulidze, O Mchedlidze, E Chkhartishvili, E Chijavadze
Present study investigated possible changes in acquisition and consolidation of associative memory in high immobilization "depressive" and low immobilization "non-depressive" rats. Question is very topical because understanding the character of learning and memory disturbances, one of symptoms of major depressive disease, is very significant for more intimate definition of the pathophysiology of major depressive disorder and appropriate searching the ways of its correction. Selection of rats according to the level of immobilization was made by means of forced swim test...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132043/the-effect-of-extract-of-greek-walnut-juglans-regia-l-septa-on-some-functional-characteristics-of-erythrocytes
#8
L Ramishvili, M Gordeziani, E Tavdishvili, N Bedineishvili, D Dzidziguri, N Kotrikadze
Administration of plant extracts for the treatment of several different diseases is an important approach ofmodern medicine.The reason must be an easy way of application, low price and the complex action of herbal medicines. The aim of the work was to study the effect of extract of walnut (Juglans regia L.) septa on the functional characteristics of erythrocytes during administration of cytotoxic agent - cyclophosphamide (experimental model of leukopenia). The material for the study was blood of the intact and experimental white mice...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132042/-reasons-and-consequences-of-somatoform-disorders-in-children-and-adolescents
#9
M Khundadze, N Geladze, R Mkheidze, N Khachapuridze, S Bakhtadze
The aim of our study was to find the reason of various forms of somatoform disorders (phobias, behavioral disorders, insomnia, tics, stuttering, enuresis, encopresis) in children and adolescents of various social status for diagnosis and treatment. We have examined 202 patients who referred to our clinic from 2012-2016. The age range was 2-18 years. After examination we have concluded the following recommendations: - to implement neuropsychological rehabilitation in order to stimulate mental development; - to work with speech therapist to improvement the speech; - to work individually with psychotherapist to improve the behavior; - to train the parent to manage the behavior at home; - to give the personal card containing information about exercises, games and puzzles to stimulate the development and in some cases to give individual educational program; - to give separate information to parents and in some cases to teachers of kindergartens and schools...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132041/-galectin-3-level-in-patients-with-acute-myocardial-infarction-and-obesity-of-different-grade-of-severity-link-with-anthropometry
#10
K Borovyk, N Ryndina, P Kravchun
The im is to estimate the concentration of galectin-3 in patients with acute myocardial infarction depending on the presence of overweight and obesity of different severity, as well as to analyze the character of the relationship of this parameter with the anthropometric indices. The study involved 78 patients with acute myocardial infarction. The study group included 55 patients with acute myocardial infarction and concomitant obesity. The control group consisted of 23 patients with acute myocardial infarction and normal body weight...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132040/erectile-dysfunction-as-a-predictor-of-cardiovascular-disease
#11
Sh Janjgava, T Doliashvili
Endothelial dysfunction precedes the clinical stage of atherosclerotic disease and is recognized as an additional risk factor when detecting symptomatic patients. Endothelial function is largely mediated by nitric oxide, and this vasodilatory mechanism is also responsible for the venous and arterial dilatation required to obtain and maintain an erection. The physiological effects and clinical aspects of sexual function have been extensively studied and reported in patients who have angina or who have experienced a myocardial infarction and in those who have undergone coronary artery bypass graft surgery or heart transplant...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132039/hepatic-arterial-anatomy-variations-in-patients-with-hepatocellular-carcinoma-evaluated-by-computed-tomography-angiography
#12
N Onashvili, M Kutateladze, N Tugushi, I Avazashvili, M Mizandari
Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and one of the major reasons for performing percutaneous endovascular procedures or liver surgery. Hepatic arterial anatomy is of major importance in performing these procedures on the liver. The aim of our study was to estimate the prevalence of various hepatic arterial variants in HCC patients. 78 patients were included in the study. Abdominal multiphase Computed Tomography scans of all patients have been assessed for presence of the hepatic arterial supply anatomical variations...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132038/-metroplasty-for-obstetric-peritonitis-arising-in-the-background-suture-failure-of-the-uterus
#13
A Tussupkaliyev, Zh Daribay, M Saduov, M Dossimbetova, G Rakhmetullina
Improving treatment outcomes obstetric peritonitis after cesarean section on the basis of organ-preserving treatment and reasonable intensive care in the postpartum period. Fifteen clinical cases in which on the background of peritonitis were made conserving surgery, which included: excision of necrotic areas on the uterus, uterine cavity curettage, metroplasty. Nasointestinal bowel intubation and drainage of the abdominal cavity. It is discussed tactics of postpartum women with obstetric peritonitis on the background of insolvency seams on the uterus, currently existing criteria for evaluation and treatment of patients data...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132037/-polyamine-concentration-in-erythrocytes-in-the-blood-of-pregnant-women-with-intrauterine-growth-retardation
#14
O Basystyi
The aim of the study was to determine polyamine concentration in erythrocytes in the blood of pregnant women with intrauterine growth retardation of different severity. The study included 100 pregnant women (from 23 to 40 weeks of gestation). The main group consisted of 80 pregnant women with intrauterine growth retardation. The control group consisted of 20 women with physiological course of pregnancy. The patients of the main group were divided into three clinical groups regarding intrauterine growth retardation staging...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132036/-evaluation-of-anthropometric-characteristics-of-pregnant-women-from-different-ethnic-and-social-groups-and-their-influence-on-the-weight-of-newborns
#15
A Kystaubayeva, Yu Semenova, G Tanysheva, I Bologan, Zh Akylzhanova
The aim of the research was to evaluate anthropometric and social characteristics of pregnant women of different ethnic groups and assess their influence on the body weight of a newborn. We conducted a retrospective cross-sectional study at 17 primary health care establishments providing antenatal care in Semey region (Kazakhstan Republic). The content analysis covered 2506 medical records of pregnant women. In our study, the differences in anthropometric indices of pregnant women of Kazakh and Russian ethnicity were statistically significant...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132035/sclerosing-microcystic-adnexal-carcinoma-of-the-scalp-case-report
#16
U Wollina, J Schönlebe
Microcystic adnexal carcinoma is a rare malignant sweat gland tumor. We present the case report of a 63 year old male patient who developed this malignancy on the scalp, which is an uncommon site. The tumor has been removed by delayed MOHS technique with no relapse. The differential diagnoses and treatment options are discussed.
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28132034/-clinical-evaluation-of-the-new-antiseptic-meshes
#17
M Gogoladze, M Kiladze, T Chkhikvadze, D Jiqia
Improving the results of hernia treatment and prevention of complications became a goal of our research which included two parts - experimental and clinical. Histomorphological and bacteriological researches showed that the best result out of the 3 control groups was received in case of covering implant "Coladerm"+ with chlorhexidine. Based on the experiment results working process continued in clinics in order to test and introduce new "coladerm"+ chlorhexidine covered poliprophilene meshes into practice. For clinical illustration there were 60 patients introduced to the research who had hernioplasty procedures by different nets: I group - standard meshes+"coladerm"+chlorhexidine, 35 patients; II group - standard meshes +"coladerm", 15 patients; III group - standard meshes, 10 patients...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009324/the-impact-of-ultraviolet-irradiation-on-morpho-functional-state-of-skin-in-guinea-pigs
#18
S Myronchenko, O Naumova, T Zvyagintseva
The purpose of this study was to assess the impact of ultraviolet irradiation (UV) on morphological and functional condition of the skin in guinea pigs. The study involved 30 albino guinea pigs weighing 400-500 g subjected to local exposure to UV irradiation. Control group consisted of intact guinea pigs. Histological studies of the skin were carried out at different stages of the trial (2 hours, 4 hours, 3 days, 8 days following the exposure). Microscopic examination showed morphological signs of acute inflammation in the skin of animals within the first three days following the exposure to UV irradiation...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009323/-to-a-question-of-treining-of-the-neonatologists-in-residency
#19
T Klimenko, E Serdceva, T Sandulak, A Zakrevskyy, O Karapetyan
: In recent years, the world and in Ukraine neonatology evolved into high-tech and quickly progressive section of the medicine, therefore preparation of experts is very important problem. Residency is the form of specialization of doctors on corresponding clinical chairs for reception of high qualifications of neonatology for possibility of competent rendering of competent and highly specialized medical care to newborns in hospitals of 3rd level. Term of training in residency is 2 years...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28009322/predicting-of-risks-of-groundwater-and-surface-water-pollution-with-different-classes-of-herbicides-in-soil-in-eastern-europe-climate-conditions
#20
M Korshun, O Dema, O Kucherenko, O Korshun, S Garkavyi, I Pelio, A Antonenko, N Velikaia
Application of pesticides in modern agriculture is a powerful permanent risk factor for public health and the natural environment. The aim of the study was a comparative hygienic assessment of the danger of contamination of ground and surface water sources with most widely used herbicides of different chemical classes (sulfonylureas, imidazolinones, pirimidinilkarboksilovye compounds semicarbazones). Field hygienic experiments for studying of the residues dynamics of studied herbicides concentration in agrocenosis objects were made by us in different types of soils: chernozem, sod-podzolic, podzolized forest...
November 2016: Georgian Medical News
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