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Evidence-based Complementary and Alternative Medicine: ECAM

Ping Zhao, Ke-Li Chen, Guo-Li Zhang, Guang-Rui Deng, Juan Li
[This corrects the article DOI: 10.1155/2017/2103254.].
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Carolina María Viola, Romina Torres-Carro, Elena Cartagena, María Inés Isla, María Rosa Alberto, Mario Eduardo Arena
In this work, we intended to inhibit the biofilm synthesis and the metabolism of Gram-positive and Gram-negative bacteria using two highly available wastes (stem and marc) obtained after the manufacturing of Torrontes wine at Cafayate, Argentina. Wine wastes contain a significant amount of bioactive compounds, mainly phenolic compounds, which makes them a potential source of compounds with beneficial properties to human health, as they could inhibit the virulence of pathogenic bacteria or protect the tissue against oxidative stress...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Kwang-Youn Kim, Tae Woo Oh, Jin-Yeul Ma, Kwang-Il Park
Lycopus lucidus Turcz. ex Benth (LT) has been broadly used as a traditional medicinal herb in Asia including Korea, China, and Japan due to its noted ability to promote blood circulation and remove blood stasis. However, its anticancer mechanism is not understood. This study aims to elucidate the effects of ethanol extracts of LT (ELT) relative to the role of Runt-related transcription factor- (Runx-) 2 in the invasive and metastatic potentials of mouse colon cancer to determine the underlying mechanisms involved...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Minfeng Wu, Yan Li, Dongjie Guo, Gang Kui, Bin Li, Yu Deng, Fulun Li
Chronic ulcer, including diabetic ulcer, varicose ulcer, and pressure ulcer, negatively affects patients' quality of life. As microbiology plays an important role in the mechanism of pathology for chronic wound healing, this study concentrates on microecology environment of the wound and how Traditional Chinese Medicine (TCM) regulates wound bacteria. Method . The study took wound samples from 35 patients and analyzed bacteria variation before and after TCM treatment by 16s rRNA sequencing. All samples were evaluated from aspects of α -diversity, β -diversity, and Simpson's Diversity index...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Yinji Liang, Yupei Zhang, Yuanjun Deng, Shu Liang, Yifang He, Yanning Chen, Chan Liu, Chenli Lin, Li Han, Guifang Tu, Qinhe Yang
We evaluate the effects of the Chaihu-Shugan-San decoction on intestinal microbe dysbiosis and chronic metabolic inflammation via the NLRP3 pathway in NAFLD rats that were fed a high-fat diet. Twenty-four SD rats (male, six weeks old, 200 ± 20 g) were randomly divided into three groups: normal control group (NC group), high-fat diet-fed group (HFD group), and Chaihu-Shugan-San decoction intervention group (CH group). The NC group rats were given standard feed, the HFD group rats were all fed a high-fat diet (83% standard feed + 10% lard oil + 5% sucrose + 1...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Leng Wei Khoo, Siew Audrey Kow, Ming Tatt Lee, Chin Ping Tan, Khozirah Shaari, Chau Ling Tham, Faridah Abas
Clinacanthus nutans (Burm.f.) Lindau (Acanthaceae), commonly known as Sabah snake grass, is a vegetable and a well-known herb that is considered an alternative medicine for insect bites, skin rashes, herpes infection, inflammation, and cancer and for health benefits. Current review aims to provide a well-tabulated repository of the phytochemical screening, identification and quantification, and the pharmacological information of C. nutans according to the experimental design and the plant preparation methods which make it outstanding compared to existing reviews...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Yun-Ning Tsai, Yi-Chia Huang, Sunny Jui-Shan Lin, Shen-Ming Lee, Yung-Yen Cheng, Yu-Hsin Chang, Yi-Chang Su
Purpose: This study aimed to clarify whether it is appropriate to choose any measurement location for pulse diagnosis research. Methods: A total of 37 subjects were recruited and measured for pulse pressure waves at 18 locations (9 per hand of "three positions and nine indicators"). These data were Fourier-transformed to the frequency spectrum, and the harmonics of C0-C10 of each location were obtained. Box plots of the harmonics were generated using SPSS v...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Dulce Morales, Guillermo Ramirez, Armando Herrera-Arellano, Jaime Tortoriello, Miguel Zavala, Alejandro Zamilpa
Current antiobesity and antidiabetic tools have been insufficient to curb these diseases and frequently cause side effects; therefore, new pancreatic lipase and α -glucosidase inhibitors could be excellent aids for the prevention and treatment of these diseases. The aim of this study was to identify, quantify, and characterize the chemical compounds with the highest degree of inhibitory activity of these enzymes, contained in a Ludwigia octovalvis hydroalcoholic extract. Chemical purification was performed by liquid-liquid separation and column chromatography...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Nuntawat Monboonpitak, Suthep Ruangwises, Sawanya Buranaphalin, Nongluck Ruangwises
Total and inorganic arsenic contents in ten commonly consumed Thai herbs, namely, bird's eye chili, cayenne pepper, celery, garlic, holy basil, kitchen mint, lemongrass, pepper, shallot, and sweet basil, were determined using atomic absorption spectrometry coupled with a hydride generation system (HG-AAS). Total arsenic contents in fresh herbs and lyophilized herbs ranged from 3.39 to 119 ng/g wet weight (wet wt) and from 41.0 to 156 ng/g dry weight (dry wt), respectively. Inorganic arsenic contents in fresh herbs and lyophilized herbs ranged from 2...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Tilahun Tolossa Jima, Moa Megersa
This paper reports an ethnobotanical study that focused on the traditional medicinal plants used by local communities to treat human diseases. Ethnobotanical study of medicinal plants was carried out from June 25 to September 5, 2015, in Berbere district of Oromia region, Ethiopia. The study focused on documentation of medicinal plants used to treat various human diseases in the study area. Ethnobotanical data were collected using semistructured interviews, group discussion, guided field walks, and observations with participants...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Jing Jiang, Ning Ding, Kang Wang, Zhigang Li
Background: Effective therapies for Alzheimer's disease (AD) are still being explored. Electroacupuncture with traditional Chinese medicine theory may improve spatial learning and memory abilities and glucose metabolism rates in an animal model of AD. However, the mechanism of electroacupuncture in intervention of AD is still unclear. According to recent studies of AD mechanisms, the NLRP3 inflammasome regulated the expression of IL-1 β in the brain which may mediate AD related processes...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Yan Guo, Liwan Xing, Chaodong Qian, Zhishan Ding, Bo Jin
Atherosclerosis is the commonest cause of death in the world and one of the most important processes that occurs with increasing age because it is accompanied by progressive endothelial dysfunction. Recent studies demonstrated that Sirtuin 1 (SIRT1) might potentially affect cell senescence. However, the effect of SIRT1 on the regulation of human umbilical vein endothelial cell (HUVEC) senescence with total flavonoids (TFs) has not been addressed previously. This study investigated how SIRT1 functions in the process of HUVEC senescence when TFs are present and identified the potential molecular mechanisms involved...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Célia Cabral, Thomas Efferth, Isabel M Pires, Patricia Severino, Marco F L Lemos
No abstract text is available yet for this article.
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Yanliu Lu, Yimei Du, Lin Qin, Di Wu, Wei Wang, Lei Ling, Feifei Ma, Hua Ling, Li Yang, Changhong Wang, Zhengtao Wang, Xumei Zhou, Yuqi He
Gypenosides extracted from Gynostemma pentaphyllum (Thunb.) Makino have significant role in reducing serum lipid level and treating fatty liver diseases, however, without clear mechanism. As gypenosides share the similar core structures with bile acids (the endogenous ligands of nuclear receptor FXR), we hypothesize that gypenosides may improve hypercholesterolemia via FXR-mediated bile acids signaling. The present study was designed to validate the role of gypenosides in reducing levels of serum total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C), as well as in regulating bile acids homeostasis and related gene expression levels...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Jee Young Kim, Thien T P Dao, Kwangho Song, Sait Byul Park, Hyeri Jang, Min Kyoung Park, Soo Ueng Gan, Yeong Shik Kim
Annona muricata L., known as graviola, is an evergreen plant of the tropical regions and is a rich source of natural products. Graviola has various biological activities, and it is best known for its anticancer activity. This study aimed to investigate the effects of crude graviola extract in vitro on breast cancer cells; in particular, we aimed to identify an agent against triple negative breast cancer (TNBC). We used the TNBC MDA-MB-231 cell line as the experimental model and the ER(+) non-TNBC MCF-7 breast cancer cell line as the control...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Alain Brice Tueche, Stephane Zingue, Edwige Nana Tchoupang, Telesphore Nanbo Gueyo, Abel Joël Gbaweng Yaya, Amstrong Nang Njuh, Dieudonnée Mireille Ntsa, Dieudonné Njamen
There is a long standing interest in the identification of medicinal plants and derived natural products for developing cancer therapeutics. The present study was designed to evaluate the in vitro and in vivo antiproliferative effects of Abyssinone V-4' methyl ether (AVME) on breast tissue of mice. The cytotoxicity of AVME was evaluated using MTT assay in four cancer cell lines (DU145, PC3, HepG2, and MCF-7). Further, a protective effect of AVME was evaluated on 7,12-dimethylbenz(a)anthracene- (DMBA-) induced breast tumor in Swiss mice...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Xiaojiao Duan, Jiarui Wu, Xingyue Huang, Kaihuan Wang, Yi Zhao, Dan Zhang, Xinkui Liu, Xiaomeng Zhang
Introduction: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) imposes a huge economic burden on healthcare systems worldwide. Chinese herbal injections (CHIs) are widely used to treat AECOPD. In this study, we examined the efficacy of CHIs in the treatment of AECOPD using a network meta-analysis (NMA). Methods: Literature search was conducted from electronic databases of randomized controlled trials (RCTs) on CHIs plus Western medicine (WM) versus WM...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Yi Shan, Jing-Juan Wang, Zhi-Qun Wang, Zhi-Lian Zhao, Mo Zhang, Jian-Yang Xu, Ying Han, Kun-Cheng Li, Jie Lu
Although acupuncture is considered to be effective and safe for Alzheimer's disease (AD) and mild cognitive impairment (MCI), the mechanism underlying its therapeutic effect is still unknown. Most studies clarifying the neuronal pathway produced by acupuncture were still applied to healthy subjects with limited single acupuncture point stimulation, which was inconsistency with clinical practice. Thus, in our present study, we investigate the differences between brain activity changes in AD and MCI patients caused by multi-acupuncture point Siguan (four gates), in order to provide visualized evidence for neuronal specificity of clinical acupuncture...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Ouyang Ping, Yang Ruixue, Deng Jiaqiang, Wang Kaiyu, Fang Jing, Geng Yi, Huang Xiaoli, Chen Defang, Lai Weimin, Tang Li, Yin Lizi
Staphylococcus aureus (S. aureus) , an important opportunistic pathogen in human and animal, causes a series of diseases in the impairing of immunity of host and even then death. Alpha-hemolysin (Hla), a primary virulence factor, plays a major role in the pathogenic progress of S. aureus , especially in pneumonia. Prim-O-glucosylcimifugin (POG), a nature chromone compound, is an active ingredient in many Chinese Medicines. In this study, POG investigated the inhibitory effect of the secretion of Hla in S. aureus strain USA300 at the subinhibitory concentrations...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Annuar Fazalda, Adam Quraisiah, Mohd Fahami Nur Azlina
Background: Peptic ulcer is a basic term for ulcers on the lower oesophagus, stomach, or jejunum. The specific term for ulcer in the stomach is gastric ulcer. The extensive use of honey around the globe helps researchers to study the usefulness of honey. Many studies had already been conducted and proved the effectiveness of honey in treating gastric ulcer. Methods: A systematic review of the literature was conducted to identify relevant studies on honey used as an alternative treatment of gastric ulcer cause by NSAIDs...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
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