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Evidence-based Complementary and Alternative Medicine: ECAM

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https://www.readbyqxmd.com/read/28105063/complementary-and-alternative-therapies-for-inflammatory-diseases
#1
EDITORIAL
Xiang Liu, Ying-Ju Lin, Yong Cheng
No abstract text is available yet for this article.
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28105062/a-56-day-oral-toxicity-study-of-the-aqueous-extract-of-rapanea-melanophloeos-l-mez-in-rats
#2
Hesbon Z Amenya, James M Mbaria, Andrew G Thaiyah, Grace N Thoithi, Peter K Gathumbi
Rapanea melanophloeos is a tropical tree that is extensively utilized in African traditional medicine to treat helminthiases, tuberculosis, and heart-water. As with many other medicinal plants, there is insufficient information regarding the safety of therapeutic R. melanophloeos extracts. An aqueous extract of R. melanophloeos stem bark was administered to Sprague Dawley rats at doses of 100 mg/kg, 300 mg/kg, and 1000 mg/kg for 56 days to characterize its potential toxicity after prolonged dosing. Blood samples were obtained fortnightly for serum chemistry and hematology, while organs were collected at the end of the study...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28105061/ginsenoside-rg3-improves-cardiac-function-after-myocardial-ischemia-reperfusion-via-attenuating-apoptosis-and-inflammation
#3
Li-Ping Zhang, Yi-Chuan Jiang, Xiao-Feng Yu, Hua-Li Xu, Min Li, Xue-Zhong Zhao, Da-Yuan Sui
Objectives. Ginsenoside Rg3 is one of the ginsenosides which are the main constituents isolated from Panax ginseng. Previous study demonstrated that ginsenoside Rg3 had a protective effect against myocardial ischemia/reperfusion- (I/R-) induced injury. Objective. This study was designed to evaluate the effect of ginsenoside Rg3 on cardiac function impairment induced by myocardial I/R in rats. Methods. Sprague-Dawley rats were subjected to myocardial I/R. Echocardiographic and hemodynamic parameters and histopathological examination were carried out...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28105060/potential-health-benefits-of-deep-sea-water-a-review
#4
REVIEW
Samihah Zura Mohd Nani, F A A Majid, A B Jaafar, A Mahdzir, M N Musa
Deep sea water (DSW) commonly refers to a body of seawater that is pumped up from a depth of over 200 m. It is usually associated with the following characteristics: low temperature, high purity, and being rich with nutrients, namely, beneficial elements, which include magnesium, calcium, potassium, chromium, selenium, zinc, and vanadium. Less photosynthesis of plant planktons, consumption of nutrients, and organic decomposition have caused lots of nutrients to remain there. Due to this, DSW has potential to become a good source for health...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28105059/investigation-of-the-key-pharmacological-activities-of-ficus-racemosa-and-analysis-of-its-major-bioactive-polyphenols-by-hplc-dad
#5
Salma Akter Sumi, Md Afjalus Siraj, Amir Hossain, Md Sagir Mia, Seagufta Afrin, Md Mustafizur Rahman
Objective. Oxidative stress leads to numerous physiological disorders including infectious diseases, inflammation, and cancer. The present study was carried out to investigate antioxidant, antibacterial, and cytotoxic activity of methanol crude extract of leaves and fruits of the Ficus racemosa (LCME and FCME, resp.) and to analyse its major bioactive polyphenols by HPLC-DAD. Methods. Antioxidant capacity of the extracts was evaluated by DPPH free radical scavenging, reducing power, total phenolic, total flavonoid, total tannin content assay, superoxide radical, hydroxyl radical, and hydrogen peroxide scavenging assay...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28105058/preventive-effects-of-the-intestine-function-recovery-decoction-a-traditional-chinese-medicine-on-postoperative-intra-abdominal-adhesion-formation-in-a-rat-model
#6
Cancan Zhou, Pengbo Jia, Zhengdong Jiang, Ke Chen, Guanghui Wang, Kang Wang, Guangbing Wei, Xuqi Li
The intestine function recovery decoction (IFRD) is a traditional Chinese medicine that has been used for the treatment of adhesive intestinal obstruction. In this study, the preventative effects and probable mechanism of the IFRD were investigated in a rat model. We randomly assigned rats to five groups: normal, model, control, low dose IFRD, and high dose IFRD. In the animal model, the caecum wall and parietal peritoneum were abraded to induce intra-abdominal adhesion formation. Seven days after surgery, adhesion scores were assessed using a visual scoring system, and histopathological samples were examined...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28105057/effects-of-integrated-traditional-chinese-and-western-medicine-for-the-treatment-of-lupus-nephritis-a-meta-analysis-of-randomized-trials
#7
REVIEW
Mingli Heng, Jinli Tu, Yu Hao, Ye Zhao, Jinhui Tian, Huaien Bu, Hongwu Wang
After a thorough search through the database as CNKI database, VIP database, Wanfang database, PubMed, and Cochrane Library, the clinical experimental articles have been selected out on the effects of Integrated Traditional Chinese and Western Medicine on the treatment of lupus nephritis. A meta-analysis was carried out in terms of clinical efficacy criteria and safety criteria by RevMan 5.3 software. Based on the results, we cautiously conclude that Integrated Traditional Chinese and Western Medicine used for lupus nephritis could improve the clinical efficacy while at same time lower the 24-hour urine protein, serum creatinine, and adverse drug reactions...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28101120/phytochemical-and-antinociceptive-anti-inflammatory-and-antioxidant-studies-of-smilax-larvata-smilacaceae
#8
Beatriz Cristina Konopatzki Hirota, Cristiane da Silva Paula, Vinícius Bednarczuk de Oliveira, Joice Maria da Cunha, Anne Karoline Schreiber, Fernanda Maria Marins Ocampos, Anderson Barison, Obdulio Gomes Miguel, Marilis Dallarmi Miguel
The tea of aerial parts of Smilax larvata Griseb. (Smilacaceae) has been ethnopharmacologically used in Southern Brazil due to its anti-inflammatory action. In this study, ethanolic and organic extracts from aerial parts of S. larvata were phytochemically and pharmacologically characterized. The phytochemical analysis of EtOAc extract of S. larvata revealed the presence of three flavonoids, drabanemoroside, kaempferol 3-O-α-L-rhamnopyranosyl(1→2)-α-L-rhamnopyranoside, and kaempferol, the first two being isolated for the first time in this genus, two phenolic compounds p-hydroxybenzoic acid and p-coumaric acid, and alkaloids...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28101119/in-vitro-antiproliferative-and-antioxidant-effects-of-extracts-from-rubus-caesius-leaves-and-their-quality-evaluation
#9
Daniel Mirosław Grochowski, Roman Paduch, Adrian Wiater, Adrianna Dudek, Małgorzata Pleszczyńska, Monika Tomczykowa, Sebastian Granica, Paulina Polak, Michał Tomczyk
The present study was performed to evaluate the effect of different extracts and subfractions from Rubus caesius leaves on two human colon cancer cell lines obtained from two stages of the disease progression lines HT29 and SW948. Tested samples inhibited the viability of cells, both HT29 and SW948 lines, in a concentration-dependent manner. The most active was the ethyl acetate fraction which, applied at the highest concentration (250 μg/mL), decreased the viability of cells (HT29 and SW948) below 66%. The extracts and subfractions were also investigated for antioxidant activities on DPPH and FRAP assays...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28101118/neuroprotective-effect-of-paeonol-mediates-anti-inflammation-via-suppressing-toll-like-receptor-2-and-toll-like-receptor-4-signaling-pathways-in-cerebral-ischemia-reperfusion-injured-rats
#10
Wen-Yen Liao, Tung-Hu Tsai, Tin-Yun Ho, Yi-Wen Lin, Chin-Yi Cheng, Ching-Liang Hsieh
Paeonol is a phenolic compound derived from Paeonia suffruticosa Andrews (MC) and P. lactiflora Pall (PL). Paeonol can reduce cerebral infarction volume and improve neurological deficits through antioxidative and anti-inflammatory effects. However, the anti-inflammatory pathway of paeonol remains unclear. This study investigated the relationship between anti-inflammatory responses of paeonol and signaling pathways of TLR2 and TLR4 in cerebral infarct. We established the cerebral ischemia-reperfusion model in Sprague Dawley rats by occluding right middle cerebral artery for 60 min, followed by reperfusion for 24 h...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28096886/fermented-chinese-formula-shuan-tong-ling-protects-brain-microvascular-endothelial-cells-against-oxidative-stress-injury
#11
Lingjing Tan, Xiang Zhang, Zhigang Mei, Jinfeng Wang, Xiaoli Li, Weifeng Huang, Songbai Yang
Fermented Chinese formula Shuan-Tong-Ling (STL), composed of fourteen medicinal herbs, was an experiential formula by Dr. Zhigang Mei for treating vascular encephalopathy, but the underlying mechanisms remained unknown. In this study, we aimed to investigate the protective effects of fermented STL on hydrogen peroxide- (H2O2-) induced injury in rat brain microvascular endothelial cells (BMECs) and the possible mechanisms. Cultured BMECs were treated with H2O2, STL, or nicotinamide (NAM, a SIRT1 inhibitor). Then, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay was employed to detect cell proliferation and senescence-associated beta-galactosidase (SA-β-gal) was used to examine cell senescence...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28096885/spatholobus-suberectus-column-extract-inhibits-estrogen-receptor-positive-breast-cancer-via-suppressing-er-mapk-pi3k-akt-pathway
#12
Jia-Qi Sun, Gan-Lin Zhang, Yi Zhang, Nan Nan, Xu Sun, Ming-Wei Yu, Hong Wang, Jin-Ping Li, Xiao-Min Wang
Although Chinese herbal compounds have long been alternatively applied for cancer treatment in China, their treatment effects have not been sufficiently investigated. The Chinese herb Spatholobus suberectus is commonly prescribed to cancer patients. HPLC analysis has shown that the main components of Spatholobus suberectus are flavonoids that can be classified as phytoestrogens, having a structure similar to estrogen. This study was designed to investigate the effects of Spatholobus suberectus column extract (SSCE) on the estrogen receptor-positive (ER+) breast cancer cell line MCF-7 and its possible molecular mechanism...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28096884/immunomodulatory-efficacy-of-standardized-annona-muricata-graviola-leaf-extract-via-activation-of-mitogen-activated-protein-kinase-pathways-in-raw-264-7-macrophages
#13
Goon-Tae Kim, Nguyen Khoi Song Tran, Eun-Hye Choi, Yoo-Jeong Song, Jae-Hwi Song, Soon-Mi Shim, Tae-Sik Park
Annona muricata, commonly known as Graviola, has been utilized as a traditional medicine to treat various human diseases. The aim of this study was to examine the immune-enhancing activity of Graviola leaf extracts in RAW 264.7 macrophage cells. Active ingredients in Graviola leaf extracts (GE) were identified as kaempferol-3-O-rutinoside and quercetin-3-O-rutinoside by LC-MS/MS. When treated with steam or 50% ethanol GE, cell morphology was altered due to initiation of cell differentiation. While the cell viability was not altered by the steam GE, it was reduced by the ethanol GE...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28090213/germinated-and-ungerminated-seeds-extract-from-two-lupinus-species-biological-compounds-characterization-and-in-vitro-and-in-vivo-evaluations
#14
Bogdan Andor, Corina Danciu, Ersilia Alexa, Istvan Zupko, Elena Hogea, Andreea Cioca, Dorina Coricovac, Iulia Pinzaru, Jenel Marian Pătrașcu, Marius Mioc, Romeo Teodor Cristina, Codruta Soica, Cristina Dehelean
In recent years, nutraceuticals attracted a great amount of attention in the biomedical research due to their significant contribution as natural agents for prevention of various health issues. Ethanolic extracts from the ungerminated and germinated seeds of Lupinus albus L. and Lupinus angustifolius L. were analyzed for the content in isoflavones (genistein) and cinnamic acid derivatives. Additionally, the extracts were evaluated for antimicrobial, antiproliferative, and anti-inflammatory properties, using in vitro and in vivo tests...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28090212/effects-of-morinda-officinalis-polysaccharide-on-experimental-varicocele-rats
#15
Lihong Zhang, Xiaozhen Zhao, Feng Wang, Qing Lin, Wei Wang
Morinda officinalis is a traditional Chinese herbal medicine, which has been used to tonify the kidney and strengthen yang for a long time in China. In this study, the effects of M. officinalis Polysaccharide (MOP) on experimental varicocele adolescent rats were investigated. The result showed that varicocele destroyed the structure of the seminiferous epithelium and decreased the TJ protein expression (Occludin, Claudin-11, and ZO-1), testosterone (T) concentration in the left testicular tissue and serum, and serum levels of inhibin B (INHB), while increasing the levels of cytokines (TGF-β3 and TNF-α) in the left testicular tissue, as well as serum levels of gonadotropin-releasing hormone (GnRH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), and antisperm antibody (AsAb)...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28090211/antimicrobial-properties-of-plant-essential-oils-against-human-pathogens-and-their-mode-of-action-an-updated-review
#16
REVIEW
Mallappa Kumara Swamy, Mohd Sayeed Akhtar, Uma Rani Sinniah
A wide range of medicinal and aromatic plants (MAPs) have been explored for their essential oils in the past few decades. Essential oils are complex volatile compounds, synthesized naturally in different plant parts during the process of secondary metabolism. Essential oils have great potential in the field of biomedicine as they effectively destroy several bacterial, fungal, and viral pathogens. The presence of different types of aldehydes, phenolics, terpenes, and other antimicrobial compounds means that the essential oils are effective against a diverse range of pathogens...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28077950/yoga-therapy-in-children-with-cystic-fibrosis-decreases-immediate-anxiety-and-joint-pain
#17
Christopher McNamara, Mahrya Johnson, Lisa Read, Heidi Vander Velden, Megan Thygeson, Meixia Liu, Laura Gandrud, John McNamara
This study was designed to determine whether yoga might alleviate symptoms of pain, sleep disturbance, anxiety, and depression in children with cystic fibrosis (CF). CF is the most common genetic, life-limiting chronic disease among Caucasian populations. It primarily affects the lungs but also many other secretory organs and consequently leads to significant morbidities. Research has shown that children with CF have significantly increased depression, anxiety, and pain compared to their healthy counterparts...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28077949/the-role-of-liuwei-dihuang-pills-and-ginkgo-leaf-tablets-in-treating-diabetic-complications
#18
Yue Zhao, Jiangyi Yu, Jingshun Liu, Xiaofei An
Objective. To observe the clinical prophylactic and therapeutic efficacy of Liuwei Dihuang Pills and Ginkgo Leaf Tablets for type 2 diabetic vascular complications. Methods. It was a randomized, double-blind and placebo-controlled clinical trial. 140 outpatients with type 2 diabetes were recruited and randomly divided into the treatment group and control group. The two groups were given basic therapy (management of blood sugar, blood pressure, etc.). Additionally, the treatment group was given Liuwei Dihuang Pills and Ginkgo Leaf Tablets, while the control group was given Liuwei Dihuang Pills and Ginkgo Leaf Tablets placebos...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28077948/exploratory-factor-analysis-for-validating-traditional-chinese-syndrome-patterns-of-chronic-atrophic-gastritis
#19
Yin Zhang, Ajian Zhou, Yue Liu, Ying Zhao, Li Zhang, Leilei Sun, Shiyu Du, Qiang Yang, Xin Song, Chaoyang Liang, Xia Ding
Background. Traditional Chinese medicine (TCM) has long been used to treat chronic atrophic gastritis (CAG). The aim of the present study was to evaluate the TCM syndrome characteristics of CAG and its core pathogenesis so as to promote optimization of treatment strategies. Methods. This study was based on a participant survey conducted in 4 hospitals in China. Patients diagnosed with CAG were recruited by simple random sampling. Exploratory factor analysis (EFA) was conducted on syndrome extraction. Results...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28074104/bufalin-inhibits-proliferation-and-induces-apoptosis-in-osteosarcoma-cells-by-downregulating-microrna-221
#20
Jianjun Zhang, Jingjing Sha, Yan Zhou, Kun Han, Yaling Wang, Yang Su, Xiuyi Yin, Haiyan Hu, Yang Yao
Bufalin, a major component of the Chinese medicine ChanSu, which is prepared from the skin and parotid venom glands of toads, has shown cytotoxicity in several malignant tumors. Here, we reported that bufalin inhibited proliferation and induced mitochondria-dependent apoptosis in U-2OS and Saos-2 osteosarcoma cells with intracellular reactive oxygen species (ROS) production. By microRNA (miR) array analysis and quantitative reverse transcription polymerase chain reaction, we found that miR-221 was downregulated after treatment with bufalin...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
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