Read by QxMD icon Read


Thomas Reijnders, Michael Schuler, Danijel Jelusic, Thierry Troosters, Wim Janssens, Konrad Schultz, Andreas von Leupoldt
Psychological factors such as negative affect have been demonstrated to impact course and treatment of chronic obstructive pulmonary disease (COPD). However, little is known about the respective impact of social factors. In several other chronic diseases, loneliness has been shown to predict morbidity, but little is known about its impact on COPD. Therefore, this study examined the associations between loneliness and outcome measures of a pulmonary rehabilitation program (PR). Before and after a 3-week inpatient PR program, patients with COPD (N = 104) underwent a 6-min walking test to measure functional exercise capacity...
November 7, 2018: COPD
Juan Marco Figueira Gonçalves, María Dolores Martín Martínez, Lina Inmaculada Pérez Méndez, Miguel Ángel García Bello, Ignacio Garcia-Talavera, Sara García Hernández, David Díaz Pérez, Natalia Bethencourt Martín
The COMCOLD score was developed to quantify the impact of comorbidities on health status in patients with chronic obstructive pulmonary disease (COPD). The objective of this study is to evaluate the association between health status in outpatients with COPD according to COMCOLD score and the GOLD 2017 groups according to symptoms (B and D vs. A and C) and exacerbations (C and D vs. A and B). 439 patients were included. The average score was 2.4 ± 3. 48% of cases had a COMCOLD score >0. The most symptomatic patients (B and D vs...
November 6, 2018: COPD
Adriana Olivares, Michele Vitacca, Laura Comini
Combining objective tools with clinical decision (CD) may help clinicians identify the priority for pulmonary rehabilitation (PR) in patients with COPD. We aimed to assess the specificity, sensitivity and efficiency of a new tool, the Pulmonary Rehabilitation Decisional Score (PRDS), and its correlation with the BODE index (BI) and CD in assigning PR priority. We retrospectively compared the three methods (CD vs. PRDS vs. BI) in 124 patients. We assigned low priority (LP), high priority (HP) and very high priority (VHP) to PR based on a priori scores of PRDS (LP = 0-10; HP = 11-17; VHP ≥18) and BI (LP = 0-2; HP = 3-5; VHP ≥6) and compared these with CD...
November 6, 2018: COPD
Janos Porszasz, Vito Brusasco
No abstract text is available yet for this article.
November 2, 2018: COPD
Ignacio Blanco, Isidro Diego, Patricia Bueno, Eloy Fernández, Francisco Casas-Maldonado, Cristina Esquinas, Joan B Soriano, Marc Miravitlles
Surveys estimating chronic obstructive pulmonary disease (COPD) prevalence are unevenly distributed in the Americas, which make it difficult to estimate accurately its geographical distribution. The geographic information system inverse distance weighted (IDW) interpolation technique has proved to be an effective tool in spatial distribution estimation of epidemiological variables, even when real data are few or widely spread. We aimed to represent cartographically the COPD prevalence in the Americas by means of a blue to red scale representation of the prevalence data, where different values are represented as different colours, and a population density filtered IDW interpolation mapping, where areas with a population density <0...
October 30, 2018: COPD
Suela Demiri, Christine Lorut, Antoine Rabbat, Daniel Luu van Lang, Aurelie Lefebvre, Jean-François Regnard, Charles-Marc Samama, Daniel Dusser, Nicolas Roche, Marco Alifano
Chronic obstructive pulmonary disease (COPD) is a risk factor of post-operative complications after lung cancer resection. The influence of the "frequent exacerbator (FE)" phenotype (at least three exacerbations per year) is unknown. Postoperative outcomes of frequent exacerbators (POFE) was a prospective observational study of patients with COPD undergoing lung resection for cancer. The inclusion criteria were: age >40 years, FEV1/FVC <70%, non-urgent surgery for lung cancer, filled out self-questionnaires...
October 30, 2018: COPD
Marceli Rocha Leite, Ercy Mara Cipulo Ramos, Ana Paula Coelho Figueira Freire, Bruna Spolador de Alencar Silva, Juliana Nicolino, Luiz Carlos Marques Vanderlei, Dionei Ramos
Despite the many benefits of performing physical exercise in patients with chronic obstructive pulmonary disease (COPD), information on the response of acute cardiac autonomic modulation in subjects with moderate and severe COPD during and after an aerobic exercise session at different intensities is unknown. The aim of this study was to evaluate the response of cardiac autonomic modulation in patients with moderate and severe COPD during and after an aerobic exercise session at different intensities. Twenty-seven patients with COPD, divided into: Moderate Group and Severe Group, underwent an aerobic exercise sessions with intensities equivalent to 60% and 90% of velocity corresponding to peak oxygen consumption...
October 30, 2018: COPD
(no author information available yet)
No abstract text is available yet for this article.
October 2, 2018: COPD
(no author information available yet)
No abstract text is available yet for this article.
October 2, 2018: COPD
Lanny S Inabnit, Christopher Blanchette, Cynthiya Ruban
Chronic Obstructive Pulmonary Disease (COPD) has a significant burden on patients and the healthcare system. There is a link between COPD and comorbidities such as congestive heart failure (CHF), fluid and electrolyte disorders, and renal failure. This adds to the complexity of healthcare in these patients. The objective of this study is to determine if certain comorbidities affect length of stay. A sample of 3,399 patients with COPD were assessed from the Premier© healthcare database. The cohort had a mean (standard deviation (SD)) age of 68...
October 1, 2018: COPD
Jinping Zheng, Nanshan Zhong, Changzheng Wang, Yijiang Huang, Ping Chen, Limin Wang, Fuxin Hui, Li Zhao, Haoyan Wang, Linda Luo, Xin Du, Aik Han Goh, David A Lipson
The FULFIL study evaluated once-daily fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) 100 µg/62.5 µg/25 µg versus twice-daily budesonide/formoterol (BUD/FOR) 400 µg/12 µg in patients with symptomatic COPD at risk of exacerbations. FULFIL demonstrated clinically meaningful and statistically significant improvements at Week 24 in trough forced expiratory volume in 1 second (FEV1 ), St George's Respiratory Questionnaire (SGRQ) Total scores and reduced exacerbation frequency. Predefined analyses were performed to evaluate treatment effects in a subgroup of patients recruited in China (China subgroup; FF/UMEC/VI, n = 32; BUD/FOR, n = 29)...
September 28, 2018: COPD
Annia Schreiber, Francesca Cemmi, Nicolino Ambrosino, Piero Ceriana, Cinzia Lastoria, Annalisa Carlucci
The aim of our study was to evaluate the prevalence and predictors of obstructive sleep apnea (OSA) in patients with chronic obstructive pulmonary disease (COPD) undergoing inpatient pulmonary rehabilitation programs (PRPs). A retrospective data review of consecutive stable patients with a known diagnosis of COPD, admitted for PRP between January 2007 and December 2013. Full overnight polysomnography (PSG) and Epworth Sleepiness Scale (ESS) were assessed in all patients. Out of 422 evaluated patients, 190 (45%) showed an Apnea Hypopnea Index (AHI) ≥ 15 events/hour and underwent OSA treatment...
September 21, 2018: COPD
Natasha Smallwood, David Currow, Sara Booth, Anna Spathis, Louis Irving, Jennifer Philip
This study explored the approaches of respiratory and palliative medicine specialists to managing the chronic breathlessness syndrome in patients with severe chronic obstructive pulmonary disease. A voluntary, online survey was emailed to all specialists and trainees in respiratory medicine in Australia and New Zealand (ANZ), and to all palliative medicine specialists and trainees in ANZ and the United Kingdom (UK). Five hundred and seventy-seven (33.0%) responses were received from 1,749 specialists, with 440 (25...
September 11, 2018: COPD
Celal Satici, Burcu Arpinar Yigitbas, Baris Seker, Mustafa Asim Demirkol, Ayse Filiz Kosar
Domiciliary noninvasive mechanical ventilation (NIMV) is used for treating patients with hypercapnic chronic obstructive pulmonary disease (COPD). We aimed to evaluate the association between adherence to the treatment and subsequent hospitalizations and costs. Data from 54 (27 adherent; 27 non-adherent) patients with COPD who were undergoing NIMV treatment at home for 6 months. We assessed adherence based on digitally recorded data and checked hospital records for clinical and laboratory data, rehospitalization rates, and costs during the following 6 months...
September 6, 2018: COPD
Basile Marco, Baiamonte Pierpaolo, Mazzuca Emilia, Principe Stefania, Pennavaria Federica, Benfante Alida, Scichilone Nicola
Individuals with Chronic Obstructive Pulmonary Disease (COPD) experience sleep disturbances due to the impact of respiratory symptoms on sleep quality. We explored whether sleep disturbances in COPD are linked to heterogeneity of airway constriction. The impact of breathing problems on sleep quality was measured in consecutive COPD outpatients with the COPD and Asthma Sleep Impact Scale (CASIS) questionnaire. Impulse oscillometry technique (IOS) was employed to assess heterogeneity of airway constriction. Subjects with a previous or concomitant diagnosis of asthma or obstructive sleep apnea (OSA) were excluded...
September 6, 2018: COPD
Linda Nici, Richard ZuWallack
Individuals with advanced chronic obstructive pulmonary disease (COPD) often have complex medical problems that require more than simple pharmacological therapy to optimize outcomes. Comprehensive care is necessary to meet the substantial burdens, not just from the primary respiratory disease process itself, but also those imposed by its systemic manifestations and comorbidities. These problems are intensified in the peri-exacerbation period, especially for newly discharged patients. Pulmonary rehabilitation, with its interdisciplinary, patient-centered and holistic approach to management, and integrated care, adding coordination or transition of care to the chronic care model, are useful approaches to meeting these complex issues...
September 5, 2018: COPD
Brenda O'Neill, Orlagh O'Shea, Suzanne McDonough, Lorcan McGarvey, Ian Bradbury, Madelynne Arden, Thierry Troosters, Denise Cosgrove, Terence McManus, Tim McDonnell, Judy Bradley
Pulmonary rehabilitation (PR) may not suit all individuals with chronic obstructive pulmonary disease (COPD) and may not result in increased physical activity. Higher levels of physical activity are associated with reduced mortality and morbidity. The aim of this study was to assess the feasibility of conducting a trial to investigate the effectiveness of a clinician-facilitated physical activity intervention (PAI) versus PR in improving physical activity in patients with COPD referred to PR. In this randomised controlled mixed methods feasibility study, all patients referred to PR who were eligible and willing were assessed at baseline and then randomised to the PAI or to PR...
September 5, 2018: COPD
Richard Casaburi
Pulmonary rehabilitation has been established as the standard of care for patients with symptomatic chronic obstructive pulmonary disease (COPD). Benefits include improvements in exercise tolerance, dyspnoea and quality of life; magnitude of benefit is generally greater than for any other COPD therapy. A wide range of professional organizations and standards documents have recommended pulmonary rehabilitation; benefits accrue across the spectrum of disease severity. However, pulmonary rehabilitation is provided to only a tiny fraction of those chronic obstructive pulmonary disease (COPD) patients who would benefit...
September 5, 2018: COPD
Prapaporn Pornsuriyasak, Mehdi Rambod, Richard M Effros, Richard Casaburi, Janos Porszasz
Oxygen uptake slow component ([Formula: see text]sc ) is associated with lactate accumulation, likely a contribution of poorly oxidative muscle fibers. We aimed to test the hypothesis that higher muscle tension during slow pedaling rates would yield more prominent [Formula: see text]sc in healthy subjects, but not in COPD patients. Eight severe COPD patients and 8 age-matched healthy individuals performed 4 rest-heavy exercise transitions at 40 and 80 RPM. Work rates at the two cadences were balanced. Venous blood was sampled for measurement of lactate concentration at rest and every 2 minutes until the end of exercise...
August 29, 2018: COPD
Gemma A Maters, Grieteke Pool, Robbert Sanderman, Johan B Wempe, Joke Fleer
No abstract text is available yet for this article.
August 2, 2018: COPD
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"