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Brazilian Journal of Otorhinolaryngology

Vitor Guo Chen, Viviane Maria Guerreiro da Fonseca, Jônatas Bussador Amaral, Cíntia Meirelles Camargo-Kosugi, Gustavo Moreira, Eduardo Macoto Kosugi, Reginaldo Raimundo Fujita
INTRODUCTION: Obstrutive sleep apnea syndrome is characterized by repeated episodes of upper airway obstruction, associated with intermittent hypoxia and hypercapnia, and the main risk factor in childhood is adenotonsillar hypertrophy. The lymphocytes in these structures are responsible for local and systemic immune responses. OBJECTIVE: Verify the levels of the inflammatory markers, IL-1β, IL-4, IL-6, IL-8, IL-10, IL-15, TNF-α, CRP and α1-GP, in the tonsils of children with and without obstructive sleep apnea syndrome...
August 31, 2018: Brazilian Journal of Otorhinolaryngology
Sthella Zanchetta, Humberto Oliveira Simões, Pamela Papile Lunardelo, Marina de Oliveira Canavezi, Ana Cláudia Mirândola Barbosa Reis, Eduardo Tanaka Massuda
INTRODUCTION: Patient-reported outcome measures, inventory and or questionnaire, allow patients to present their perspective of the impact of their individual condition on a day-to-day basis, independent of the analysis of test results by the expert clinician. Outcome measures are recommended when there is evidence showing their reliability, validity and sensitivity. There are standardized patient-reported outcome measures for hearing in English language; however, other languages lack these instruments...
August 30, 2018: Brazilian Journal of Otorhinolaryngology
Kerem Sami Kaya, Bilge Türk, Mahmut Cankaya, Nurullah Seyhun, Berna Uslu Coşkun
INTRODUCTION: The face is the most important factor affecting the physical appearance of a person. In facial aesthetics, there is a specific mathematical proportion, which is called golden proportion, used to measure and analyse facial aesthetic qualities in population. OBJECTIVES: The aim of this study was to measure the facial soft tissue proportions which would help to constitute a standard for facial beauty and diagnose facial differences and anomalies and to compare these proportions to the golden proportion...
August 18, 2018: Brazilian Journal of Otorhinolaryngology
Gabriela Felix Lazarini Almeida, Marcella Ferrari Martins, Lucas Bevilacqua Alves da Costa, Orozimbo Alves da Costa, Ana Claudia Martinho de Carvalho
INTRODUCTION: The use of the bilateral cochlear implants can promote the symmetrical development of the central auditory pathways, thus benefiting the development of auditory abilities and improving sound localization and the ability of auditory speech perception in situations of competitive noise. OBJECTIVE: To evaluate the ability of speech perception in children and adolescents using sequential bilateral cochlear implants, considering the association of these variables: age at surgery, time of device use and interval between surgeries...
August 18, 2018: Brazilian Journal of Otorhinolaryngology
Maura Catafesta das Neves, Fabricio Ricci Romano, Samuel Guerra Filho
INTRODUCTION: The use of saline irrigation for nasal washes is a well established procedure in the treatment of sinonasal inflammation and infection. In addition to saline solutions, Ringer's lactate is also an efficient option for nasal washes and humidification. OBJECTIVE: To assess the comfort, humidification and tolerance regarding stinging sensation, provided by sodium chloride nasal gel at the concentrations of 4.5mg/g and 6.0mg/g through questionnaires answered by the patients...
August 8, 2018: Brazilian Journal of Otorhinolaryngology
Fatma Caylakli
No abstract text is available yet for this article.
August 7, 2018: Brazilian Journal of Otorhinolaryngology
Muhammed Sedat Sakat, Korhan Kilic, Fazile Nur Ekinci Akdemir, Serkan Yildirim, Gizem Eser, Ahmet Kiziltunc
INTRODUCTION: Ototoxicity refers to cellular damage or function impairment developing in the inner ear in association with any therapeutic agent or chemical substance, and still represents the principal side-effect restricting the use of cisplatin. OBJECTIVE: The aim of this study was to perform a biochemical, functional and histopathological investigation of the potential protective effect of eugenol against cisplatin-induced ototoxicity. METHODS: The study was performed with 24 female Sprague Dawley rats...
August 7, 2018: Brazilian Journal of Otorhinolaryngology
Taku Ito, Satoshi Ikeda, Tomoaki Asamori, Keiji Honda, Yoshiyuki Kawashima, Ken Kitamura, Keiko Suzuki, Takeshi Tsutsumi
INTRODUCTION: Chronic rhinosinusitis with nasal polyps is a heterogeneous disease and appropriate diagnostic algorithms in individual cases are necessary for effective medical treatment. OBJECTIVE: The purpose of this study was to clarify the relationship between the pendrin expression of nasal polyps and clinical and pathological characteristic features of eosinophilic chronic rhinosinusitis. METHODS: A total of 68 patients were classified into eosinophilic chronic rhinosinusitis or non-eosinophilic chronic rhinosinusitis groups according to the degree of eosinophilic infiltration into the nasal polyps...
August 7, 2018: Brazilian Journal of Otorhinolaryngology
Michał Żurek, Anna Rzepakowska, Ewa Osuch-Wójcikiewicz, Kazimierz Niemczyk
INTRODUCTION: The endoscopic methods are progressing and becoming more common in routine clinical diagnosis in the field of otorhinolaryngology. Relatively large amount of researches have proved high accuracy of narrow band imaging endoscopy in differentiating benign and malignant lesions within vocal folds. However, little is known about learning curve in narrow band imaging evaluation of laryngeal lesions. OBJECTIVE: The aim of this study was to determine the learning curve for the narrow band imaging evaluation of vocal folds pathologies depending on the duration of the procedure...
August 4, 2018: Brazilian Journal of Otorhinolaryngology
Shibo Sun, Huifen Zhai, Mei Zhu, Peili Wen, Xin He, Haoyan Wang
INTRODUCTION: Obstructive sleep apnea, a common disease, is usually complicated by insulin resistance and type 2 diabetes mellitus. Adipokine is considered to play an important role in the development of insulin resistance and type 2 diabetes mellitus in obstructive sleep apnea. OBJECTIVE: To assess whether secreted frizzled-related protein 5, a new adipokine, is involved in untreated obstructive sleep apnea patients. METHODS: Seventy-six subjects with obstructive sleep apnea and thirty-three control subjects without obstructive sleep apnea were recruited and matched in terms of body mass index and age...
August 4, 2018: Brazilian Journal of Otorhinolaryngology
Jing Chen, Hai Liang Li, Bo Bo Li, Wei Li, Dong Ma, Yong He Li, Tao Liu
INTRODUCTION: Serum- and glucocorticoid-inducible kinase 3, a serine/threonine kinase that functions downstream of the PI3K signaling pathway, plays a critical role in neoplastic processes. It is expressed by various tumors and contributes to carcinogenesis. OBJECTIVE: The objective was to investigate serum- and glucocorticoid-inducible kinase 3 expression in nasopharyngeal carcinoma, to study the anti-tumor effects of serum- and glucocorticoid-inducible kinase 3 shRNA by inhibiting its expression in nasopharyngeal carcinoma cells and to discuss the potential implications of our findings...
July 18, 2018: Brazilian Journal of Otorhinolaryngology
Lalee Varghese, Sramana Mukhopadhyay, Raghav Mehan, Regi Kurien, Meera Thomas, V Rupa
INTRODUCTION: Sinonasal organising haematoma is a recently described, rare, benign inflammatory condition, which closely resembles malignancy in its clinical presentation. OBJECTIVE: To describe the clinical features of organising haematoma and to review the evolution of surgical options successfully used. METHODS: A retrospective review of charts of all patients with a histopathological diagnosis of sinonasal organising haematoma was performed...
July 17, 2018: Brazilian Journal of Otorhinolaryngology
Fernando de Andrade Quintanilha Ribeiro
No abstract text is available yet for this article.
July 17, 2018: Brazilian Journal of Otorhinolaryngology
Gabriela Costa Andrade, Flavia Coimbra Pontes Maia, Gabriela Franco Mourão, Pedro Weslley Rosario, Maria Regina Calsolari
INTRODUCTION: The side effects of antithyroid drugs are well known. Antineutrophil cytoplasmic antibody-associated vasculitis is a severe adverse reaction. Most studies evaluating antineutrophil cytoplasmic antibodies related to antithyroid drugs have been carried out with patients treated with propylthiouracil, but less information is available for methimazole. Furthermore, most studies that investigated antineutrophil cytoplasmic antibodies related to antithyroid drugs were conducted on Asian populations...
July 17, 2018: Brazilian Journal of Otorhinolaryngology
Emrah Sapmaz, Yuksel Toplu, Battal Tahsin Somuk
INTRODUCTION: Septal perforation is a condition characterized by loss of cartilage and/or bony structures along with the mucoperichondrium and mucoperiosteum lining them. The etiology includes a history of nasal surgery or trauma, nose picking, bilateral septal cauterization, overuse of nasal sprays, cocaine abuse, vasculitis, and malignancies. OBJECTIVE: Comparison of quality of life in patients with septal perforation after conservative or surgical treatment, and a new approach for the determination of the diameter of the perforation from a different point of view...
July 17, 2018: Brazilian Journal of Otorhinolaryngology
Gun Hee Yu, Yong-Jun Choi, Hahn Jin Jung, Yun-Sung Lim, Seok-Won Park, Chang Gun Cho, Joo Hyun Park
INTRODUCTION: Glucocorticoids are considered the first-line therapy for sudden sensorineural hearing loss. But there is currently no consensus on administering them as a single dose versus multiple divided daily doses. OBJECTIVE: We aim to evaluate the treatment outcome of sudden sensorineural hearing loss between a single-dose and multiple divided daily doses of steroid treatment. METHODS: A total of 94 patients who were diagnosed and treated for sudden sensorineural hearing loss and followed up for more than three months were reviewed retrospectively...
July 17, 2018: Brazilian Journal of Otorhinolaryngology
Józef Mierzwiński, Justyna Tyra, Karolina Haber, Maria Drela, Dariusz Paczkowski, Michael David Puricelli, Anna Sinkiewicz
INTRODUCTION: Acute mastoiditis remains the most common complication of acute otitis media. It may rarely appear also in cochlear implant patients. However, the treatment recommendations for this disease are not precisely defined or employed, and in the current literature the differences regarding both the diagnosis and management are relatively substantial. OBJECTIVE: The aim of this study was to determine a standard and safe procedure to be applied in case of pediatric acute mastoiditis...
July 17, 2018: Brazilian Journal of Otorhinolaryngology
Maria Fernanda Capoani Garcia Mondelli, Ivan Dos Santos José, Maria Renata José, Natália Barreto Frederigue Lopes
INTRODUCTION: There is evidence pointing to the importance of the evaluation of musical perception through objective and subjective instruments. In Brazil, there is a shortage of instruments that evaluates musical perception. OBJECTIVE: To develop an instrument to evaluate the recognition of traditional Brazilian melodies and investigate the performance of children with typical hearing. METHODS: The study was carried out after approval of the research ethics committee (1...
June 30, 2018: Brazilian Journal of Otorhinolaryngology
Mario A Castro, Rogério A Dedivitis, João M Salge, Leandro L Matos, Claudio R Cernea
INTRODUCTION: The post-laryngectomy state is characterized by several alterations in lung function. A reliable estimation of lung function can be very useful in laryngectomees to prevent postoperative complications and to evaluate the results of the treatment. OBJECTIVE: Characterize the presence of respiratory functional disorders and the functional pattern of laryngectomees through the use of an extratracheal device. METHODS: This transversal study included 50 patients submitted to total laryngectomy at least 6 months prior to this investigation, as the treatment of choice for laryngeal cancer...
June 29, 2018: Brazilian Journal of Otorhinolaryngology
Moncef Sellami, Slim Charfi, Mohamed Amine Chaabouni, Salma Mrabet, Ilhem Charfeddine, Lobna Ayadi, Souha Kallel, Abdelmonem Ghorbel
INTRODUCTION: The fine-needle cytology is being used as a first line of investigation in the diagnosis of head and neck swellings, as it is simple, cost effective and less invasive as compared to biopsy. OBJECTIVE: The aims of this study were to evaluate the results of the fine-needle non-aspiration cytology of cervical lymphadenopathy and to study the factors influencing the rate of non-diagnosis results. METHODS: This retrospective study was conducted on selected patients with cervical lymphadenopathy that had undergone a fine-needle non-aspiration cytology followed by a histological biopsy...
June 28, 2018: Brazilian Journal of Otorhinolaryngology
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