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Esophagus: Official Journal of the Japan Esophageal Society

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https://www.readbyqxmd.com/read/30178429/novel-prognostic-score-of-postoperative-complications-after-transthoracic-minimally-invasive-esophagectomy-for-esophageal-cancer-a-retrospective-cohort-study-of-90-consecutive-patients
#1
Takahiro Saito, Kimitaka Tanaka, Yuma Ebihara, Yo Kurashima, Soichi Murakami, Toshiaki Shichinohe, Satoshi Hirano
BACKGROUND: Esophagectomy is the standard treatment for esophageal cancer, but has a high rate of postoperative complications. Some studies reported the various scoring system to estimate the postoperative complications. However, there were according to various surgical methods and included intra- and post-operative factors. Recently, minimally invasive esophagectomy (MIE) is becoming the first-line treatment for esophageal cancer. The aim of this study was to investigate the risk factors of postoperative complications and to establish a useful system for predicting postoperative complications after transthoracic MIE...
September 3, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30173282/construction-of-a-risk-model-for-the-development-of-metachronous-squamous-cell-carcinoma-after-endoscopic-resection-of-esopahageal-squamous-cell-carcinoma
#2
Yuji Urabe, Kenichi Kagemoto, Koki Nakamura, Takeshi Mizumoto, Yoji Sanomura, Shiro Oka, Hidenori Ochi, Shinji Tanaka, Kazuaki Chayama
BACKGROUND: Previously, we identified that rs1229984 in ADH1B, rs671 in ALDH2, and smoking status were independently associated with the risk of developing metachronous squamous cell carcinoma (SCC) after endoscopic resection (ER) for esophageal SCC (ESCC). However, this analysis included cases with short-term follow-up. In the present study, we investigated the environmental and genetic factors associated with developing metachronous SCC using long-term follow-up observation after ER for ESCC...
September 1, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30171414/esophageal-cancer-practice-guidelines-2017-edited-by-the-japan-esophageal-society-part-2
#3
Yuko Kitagawa, Takashi Uno, Tsuneo Oyama, Ken Kato, Hiroyuki Kato, Hirofumi Kawakubo, Osamu Kawamura, Motoyasu Kusano, Hiroyuki Kuwano, Hiroya Takeuchi, Yasushi Toh, Yuichiro Doki, Yoshio Naomoto, Kenji Nemoto, Eisuke Booka, Hisahiro Matsubara, Tatsuya Miyazaki, Manabu Muto, Akio Yanagisawa, Masahiro Yoshida
No abstract text is available yet for this article.
August 31, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30171413/esophageal-cancer-practice-guidelines-2017-edited-by-the-japan-esophageal-society-part-1
#4
Yuko Kitagawa, Takashi Uno, Tsuneo Oyama, Ken Kato, Hiroyuki Kato, Hirofumi Kawakubo, Osamu Kawamura, Motoyasu Kusano, Hiroyuki Kuwano, Hiroya Takeuchi, Yasushi Toh, Yuichiro Doki, Yoshio Naomoto, Kenji Nemoto, Eisuke Booka, Hisahiro Matsubara, Tatsuya Miyazaki, Manabu Muto, Akio Yanagisawa, Masahiro Yoshida
No abstract text is available yet for this article.
August 31, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30155745/survival-benefit-of-multimodal-local-therapy-for-repeat-recurrence-of-thoracic-esophageal-squamous-cell-carcinoma-after-esophagectomy
#5
Itasu Ninomiya, Koichi Okamoto, Sachio Fushida, Jun Kinoshita, Hiroyuki Takamura, Hidehiro Tajima, Isamu Makino, Tomoharu Miyashita, Tetsuo Ohta
BACKGROUND: This study was performed to clarify the optimal therapeutic strategy for recurrent disease after esophagectomy. METHODS: We investigated the prognosis of 37 patients who developed recurrence among 128 patients who underwent curative thoracoscopic esophagectomy (TE) at Kanazawa University Hospital. The prognostic factors after recurrence were examined by univariate and multivariate analyses. RESULTS: Of these 37 recurrences, 29 patients underwent local therapy (surgery, 10 patients; surgery followed by radiation, 2 patients; radiation, 17 patients)...
August 28, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30151653/interactions-between-helicobacter-pylori-and-gastroesophageal-reflux-disease
#6
REVIEW
Oya Yucel
Interactions between Helicobacter Pylori (HP) and gastroesophageal reflux disease (GERD) are a complex issue. Several pathophysiological factors influence the development and the course of GERD, HP infection might be only one of these. Many studies emphasize the co-existence of these diseases. HP infection could contribute to GERD through both a protective and an aggressive role. Gastric acid secretion is a key factor in the pathophysiology of reflux esophagitis. Depending on the type of gastritis related to HP, acid secretion may either increase or decrease...
August 27, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30145681/circumferential-distribution-and-clinical-characteristics-of-esophageal-cancer-in-lower-esophagus-differences-related-to-histological-subtype
#7
Mayumi Okada, Norihisa Ishimura, Hironobu Mikami, Eiko Okimoto, Naoki Oshima, Youichi Miyaoka, Hirofumi Fujishiro, Shunji Ishihara, Yoshikazu Kinoshita
BACKGROUND: Esophageal adenocarcinoma (EAC) is frequently found on the right-anterior wall of the distal esophagus in short-segment Barrett's esophagus (SSBE) patients. However, the endoscopic characteristics of EAC in cases with long-segment BE (LSBE) and squamous cell carcinoma (ESCC) in the lower esophagus remain to be fully evaluated. Here, we determined the circumferential distribution and clinical characteristics of esophageal cancer occurring in the lower esophagus based on histological subtype...
August 25, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30145680/the-assessment-of-the-esophageal-motility-of-children-with-esophageal-disorders-by-the-detailed-observation-of-the-ph-multichannel-intraluminal-impedance-waveform-and-baseline-impedance-screening-test-potential
#8
Daisuke Masui, Suguru Fukahori, Shinji Ishii, Naoki Hashizume, Nobuyuki Saikusa, Motomu Yoshida, Naruki Higashidate, Saki Sakamoto, Shiori Tsuruhisa, Hirotomo Nakahara, Yoshiaki Tanaka, Minoru Yagi
BACKGROUND: The present study aimed to evaluate whether the detailed observation of pH/MII waveforms and the analysis of baseline impedance (BI) values could detect esophageal dysmotility in pediatric patients with esophageal disorders. PATIENTS AND METHODS: Eleven patients with congenital esophageal disorder in whom pH/MII was conducted from April 2011 to June 2015, were enrolled in this study. The diagnoses of the patients were as follows: postoperative esophageal atresia (EA), n = 6; esophageal achalasia (EAch), n = 4; and congenital esophageal stenosis (CES), n = 1...
August 25, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30099640/a-new-esophageal-elongation-technique-for-long-gap-esophageal-atresia-in-vitro-comparison-of-myotomy-techniques
#9
Burhan Beger, Orhan Beger
BACKGROUND: Complications such as stricture, leakage, recurrent tracheoesophageal fistula and mucosal pouch are commonly seen in myotomy techniques used for long-gap esophageal atresia (LGEA) treatments. Therefore, we think that there is a clear need for other techniques which would enable us to create more robust and longer esophagus in such cases. In this study, we reviewed multiple V-myotomy (VM) technique and the differences of the said technique with Livaditis circular myotomy (LM) and Kimura spiral myotomy (KM) techniques using literature as an aid...
August 11, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30097829/comparison-of-esophageal-submucosal-glands-in-experimental-models-for-esophagus-tissue-engineering-applications
#10
Amulya K Saxena, Guenther Klimbacher
OBJECTIVE: Esophagus tissue engineering holds promises to overcome the limitations of the presently employed esophageal replacement procedures. This study investigated 5 animal models for esophageal submucosal glands (ESMG) to identify models appropriate for regenerative medicine applications. Furthermore, this study aimed to measure geometric parameters of ESMG that could be utilized for fabrication of ESMG-specific scaffolds for esophagus tissue engineering applications. METHODS: Ovine, avian, bovine, murine, and porcine esophagus were investigated using Hematoxylin-Eosin (HE), Periodic Acid Schiff (PAS), and Alcian Blue (AB), with AB applied in 3 pH levels (0...
August 10, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30074105/robot-assisted-mediastinoscopic-esophagectomy-for-esophageal-cancer-the-first-clinical-series
#11
Masaya Nakauchi, Ichiro Uyama, Koichi Suda, Susumu Shibasaki, Kenji Kikuchi, Shinichi Kadoya, Yoshinori Ishida, Kazuki Inaba
BACKGROUND: Radical esophagectomy for esophageal cancer is associated with high morbidity, especially with pulmonary complications. Mediastinoscopic esophagectomy via a small left neck incision combined with the esophageal hiatus, without using transthoracic approach, has been reported to reduce pulmonary complication; however, from technical point of view, this approach using non-articulating, straight, long forceps is extremely challenging, especially in the middle mediastinal area...
August 3, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30073428/observation-of-the-cytoarchitecture-of-the-human-esophageal-mucosa-with-special-attention-to-the-lamina-muscularis-mucosae-and-the-distribution-of-lymphatic-vessels
#12
Tomotaka Shibata, Kaoruko Takita, Masafumi Inomata
The cytoarchitecture of the esophageal mucosa was examined by using light microscopy, transmission electron microscopy, and scanning electron microscopy. The cytoarchitecture of the muscularis mucosae varied greatly among the cervical, thoracic, and abdominal esophagus, especially in the cervical esophagus, the muscularis mucosae suffered a loss and the distribution of lymphatic vessels also varied according to the site. It was suggested that these morphological differences would have a strong influence on the infiltration of esophageal cancer and the mode of lymph node metastasis...
August 2, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30056606/inter-institutional-variations-regarding-barrett-s-esophagus-diagnosis
#13
Norihisa Ishimura, Mika Yuki, Takafumi Yuki, Yoshinori Komazawa, Yoshinori Kushiyama, Hirofumi Fujishiro, Shunji Ishihara, Yoshikazu Kinoshita
BACKGROUND: Barrett's esophagus (BE) is a known precursor for development of esophageal adenocarcinoma and surveillance of affected patients is necessary when cancer progression risk is considered to be high. However, the accuracy of BE diagnosis may not be homogenous among institutions with endoscopy units. We investigated inter-institutional variability by examining the accuracy of endoscopic diagnosis of BE at 4 different hospitals. METHODS: The accuracy of BE diagnosis at the 4 hospitals was retrospectively reviewed by 6 expert endoscopists, who independently reviewed endoscopic images of approximately 500 consecutive patients examined at each hospital without information regarding the diagnosis by the on-site endoscopists...
July 28, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30030739/perioperative-enteral-supplementation-with-glutamine-fiber-and-oligosaccharide-reduces-early-postoperative-surgical-stress-following-esophagectomy-for-esophageal-cancer
#14
Tetsuya Abe, Takahiro Hosoi, Ryosuke Kawai, Norihisa Uemura, Eiji Higaki, Byonggu An, Jiro Kawakami, Takuya Saito, Yasuhiro Shimizu
BACKGROUND: We clarified the effects of perioperative enteral supplementation with glutamine, fiber, and oligosaccharide (GFO) after an esophagectomy on preventing surgical stress. METHODS: Of 326 patients with esophageal cancer, 189 received GFO administration (GFO group) and 137 did not (control group). The propensity score matching method was used to identify 89 well-balanced pairs of patients to compare postoperative laboratory parameters and clinical and postoperative outcomes...
July 20, 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30225745/the-effect-of-an-elemental-diet-on-oral-mucositis-of-esophageal-cancer-patients-treated-with-dcf-chemotherapy-a-multi-center-prospective-feasibility-study-epoc-study
#15
Yoshihiro Tanaka, Takao Ueno, Naoya Yoshida, Yasunori Akutsu, Hiroya Takeuchi, Hideo Baba, Hisahiro Matsubara, Yuko Kitagawa, Kazuhiro Yoshida
PURPOSE: Oral mucositis (OM) is one of the most uncomfortable adverse events experienced by cancer patients undergoing chemotherapy. Previous reports have revealed that the oral administration of an elemental diet (ED) may prevent OM. However, the incidence of OM has not been accurately determined by specialized diagnostic methods and the effects of an ED on OM remain unclear. We investigated the dose that could feasibly be administered and its effects with regard to the suppression of OM in esophageal cancer patients undergoing chemotherapy...
October 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30225744/association-of-level-of-anastomosis-and-anastomotic-leak-after-esophagectomy-in-anterior-mediastinal-reconstruction
#16
Katsunori Nishikawa, Tetsuji Fujita, Yako Hasegawa, Yujiro Tanaka, Akira Matsumoto, Norio Mitsumori, Katsuhiko Yanaga
AIM: The purpose of this study was to investigate modifiable predisposing factors associated with anastomotic leak in the anterior mediastinal (AM) reconstruction route. METHODS: We reviewed the data on 154 patients who underwent esophagectomy and gastric tube reconstruction using the AM route between 2008 and 2016. The data included computed tomography (CT) scans with sagittal reconstruction of the thoracic section. The level of the esophagogastric anastomosis (LEA) and pretracheal distance (PTD) was measured from sagittal reconstructed CT images...
October 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30225743/lateral-thermal-spread-and-recurrent-laryngeal-nerve-paralysis-after-minimally-invasive-esophagectomy-in-bipolar-vessel-sealing-and-ultrasonic-energy-devices-a-comparative-study
#17
Kazuo Koyanagi, Fumihiko Kato, Keita Nakanishi, Soji Ozawa
BACKGROUND: This study aimed to compare the extent of lateral thermal spread of surrounding tissues after the use of advanced bipolar and ultrasonic coagulation and shearing devices. Association between recurrent laryngeal nerve paralysis (RLNP) and such devices was assessed in patients who underwent minimally invasive esophagectomy (MIE). METHODS: LigaSure™ (LS) and Sonicision™ (SONIC) were used. In ex vivo experiments using the porcine muscle, blade temperature and tissue temperature were measured using a thermometer after the activation of both devices...
October 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30225742/involved-field-chemoradiotherapy-for-postoperative-solitary-lymph-node-recurrence-of-esophageal-cancer
#18
Terufumi Kawamoto, Keiji Nihei, Keisuke Sasai, Katsuyuki Karasawa
BACKGROUND: For patients with postoperative lymph node (LN) recurrent esophageal cancer, the appropriate irradiation field in chemoradiotherapy (CRT) remains controversial. We assessed the clinical outcomes and prognostic factors related to involved-field CRT for postoperative solitary LN recurrence of esophageal squamous cell carcinoma (ESCC). METHODS: We retrospectively evaluated 21 patients who had received curative resection, with LN recurrence of ESCC. Patients received CRT using 5-fluorouracil plus cisplatin or docetaxel, prescribed at 60 Gy in 30 fractions...
October 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30225741/surgical-results-of-laparoscopic-toupet-fundoplication-for-gastroesophageal-reflux-disease-with-special-reference-to-recurrence
#19
Nobuo Omura, Fumiaki Yano, Kazuto Tsuboi, Masato Hoshino, SeRyung Yamamoto, Shunsuke Akimoto, Takahiro Masuda, Hideyuki Kashiwagi, Katsuhiko Yanaga
BACKGROUND: Surgical results of GERD have mainly been reported from the Western countries, with a few reports found in Japan. We examined the surgical results of laparoscopic Toupet fundoplication and clarify the characteristics of recurrent cases. METHODS: The subjects included 375 patients who underwent laparoscopic Toupet fundoplication from June 1997 to December 2016 as the initial surgery. Patient characteristics, pathophysiology, and surgical results were examined...
October 2018: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/30225740/hyponatremia-in-patients-with-esophageal-cancer-treated-with-chemotherapy-including-cisplatin
#20
Ayako Shimada, Hiroya Takeuchi, Kazumasa Fukuda, Koichi Suda, Rieko Nakamura, Norihito Wada, Hirofumi Kawakubo, Yuko Kitagawa
BACKGROUND: Little is known about hyponatremia in patients with esophageal cancer treated with cisplatin-based chemotherapy. The aim of this study was to analyze the risk factors for hyponatremia and its effect on outcomes in patients with esophageal cancer treated with chemotherapy including cisplatin. METHODS: We retrospectively analyzed the records of 137 patients with esophageal cancer who received chemotherapy including cisplatin for the first time between January 2011 and December 2014...
October 2018: Esophagus: Official Journal of the Japan Esophageal Society
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