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Heart Rhythm: the Official Journal of the Heart Rhythm Society

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https://www.readbyqxmd.com/read/28522367/qrs-t-wave-and-calcium-alternans-in-a-type-i-diabetic-mouse-model-for-spontaneous-post-myocardial-infarction-ventricular-tachycardia-a-mechanism-for-the-antiarrhythmic-effect-of-statins
#1
Hongwei Jin, Charles M Welzig, Mark Aronovitz, Farzad Noubary, Robert Blanton, Bo Wang, Mohammad Rajab, Alfred Albano, Mark S Link, Sami F Noujaim, Ho-Jin Park, Jonas B Galper
BACKGROUND: The incidence of sudden arrhythmic death is markedly increased in diabetics. OBJECTIVE: Develop a mouse model for Post MI VT in the diabetic heart and determine the mechanism of an antiarrhythmic effect of statins. METHODS: EKG transmitters were implanted in wild type (WT), placebo and pravastatin treated Type I diabetic Akita mice, MIs induced by coronary ligation, Ca(2+) transients studied by optical mapping, Ca(2+) transients and sparks in left VM (VM) by the Ionoptix system and confocal microscopy...
May 15, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28506918/cardiac-resynchronization-therapy-utilizing-permanent-his-bundle-pacing-are-we-there-yet
#2
EDITORIAL
Pugazhendhi Vijayaraman
No abstract text is available yet for this article.
May 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28506917/atrial-antitachycardia-pacing-and-atrial-remodeling-a-substudy-of-the-international-randomized-minerva-trial
#3
Giuseppe Boriani, Raymond Tukkie, Mauro Biffi, Lluis Mont, Renato Ricci, Helmut Pürerfellner, Giovanni Luca Botto, Antonis S Manolis, Maurizio Landolina, Michele Gulizia, J Harrison Hudnall, Lorenza Mangoni, Andrea Grammatico, Luigi Padeletti
BACKGROUND: Atrial tachycardia (AT) and atrial fibrillation (AF) are common in pacemaker patients and are associated with bad prognosis. OBJECTIVE: To evaluate atrial antitachycardia pacing impact on AT/AF induced atrial remodeling, measured by early recurrence of AT/AF (ERAF) and by change in left atrium diameter (LAD). To evaluate impact of AT/AF duration on ERAF incidence. METHODS: Pacemaker patients were randomized to dual-chamber pacing (Control DDDR-385 patients), managed ventricular pacing (MVP-398 patients) or atrial antitachycardia pacing plus MVP (DDDRP+MVP-383 patients)...
May 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28506916/temporary-removal-2017-hrs-ehra-ecas-aphrs-solaece-expert-consensus-statement-on-catheter-and-surgical-ablation-of-atrial-fibrillation
#4
Hugh Calkins, Gerhard Hindricks, Riccardo Cappato, Young-Hoon Kim, Eduardo B Saad, Luis Aguinaga, Joseph G Akar, Vinay Badhwar, Josep Brugada, John Camm, Peng-Sheng Chen, Shih-Ann Chen, Mina K Chung, Jens Cosedis Nielsen, Anne B Curtis, D Wyn Davies, John D Day, André d'Avila, N M S Natasja de Groot, Luigi Di Biase, Mattias Duytschaever, James R Edgerton, Kenneth A Ellenbogen, Patrick T Ellinor, Sabine Ernst, Guilherme Fenelon, Edward P Gerstenfeld, David E Haines, Michel Haissaguerre, Robert H Helm, Elaine Hylek, Warren M Jackman, Jose Jalife, Jonathan M Kalman, Josef Kautzner, Hans Kottkamp, Karl Heinz Kuck, Koichiro Kumagai, Richard Lee, Thorsten Lewalter, Bruce D Lindsay, Laurent Macle, Moussa Mansour, Francis E Marchlinski, Gregory F Michaud, Hiroshi Nakagawa, Andrea Natale, Stanley Nattel, Ken Okumura, Douglas Packer, Evgeny Pokushalov, Matthew R Reynolds, Prashanthan Sanders, Mauricio Scanavacca, Richard Schilling, Claudio Tondo, Hsuan-Ming Tsao, Atul Verma, David J Wilber, Teiichi Yamane
The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal.
May 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28506915/long-qt-syndrome-who-needs-a-transplant
#5
EDITORIAL
Sairah Khan, Charles I Berul
No abstract text is available yet for this article.
May 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28506913/predicting-determinants-of-atrial-fibrillation-or-flutter-for-therapy-elucidation-in-patients-at-risk-for-thromboembolic-events-predate-af-study
#6
Javed M Nasir, William Pomeroy, Adam Marler, Matthew Hann, Tina Baykaner, Ronald Jones, Richard Stoll, Katherine Hursey, Angela Meadows, Jennifer Walker, Steve Kindsvater
BACKGROUND: Atrial fibrillation (AF) is the most common clinically significant cardiac rhythm disorder. There is considerable interest in screening for AF, as it is a leading cause of stroke, and oral anticoagulants (OACs) have been shown to significantly reduce the risk of stroke in patients with AF. Improved screening for AF with subsequent treatment may help improve long-term outcomes, but the optimal patient population and screening intensity are unknown. OBJECTIVES: In this study, we prospectively evaluated the use of the CHA2DS2-VASc score for the prediction of new-onset AF using insertable cardiac monitors (ICMs) and examined whether this screening led to the initiation of OAC therapy...
May 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28502873/synchronization-as-a-mechanism-for-low-energy-anti-fibrillation-pacing-leap
#7
Yanyan Claire Ji, Ilija Uzelac, Niels Otani, Stefan Luther, Robert F Gilmour, Elizabeth M Cherry, Flavio H Fenton
BACKGROUND: Low-energy anti-fibrillation pacing (LEAP) has been suggested as an alternative treatment to symptomatic fibrillation patients. It significantly lowers the energy required compared with standard one-shock defibrillation. OBJECTIVE: In this study, we investigated the mechanism of arrhythmia termination by LEAP and systematically analyzed the influence of shock period and timing on the success rate of LEAP. METHODS: We induced atrial and ventricular fibrillation in isolated canine hearts and applied LEAP and standard one-shock defibrillation to terminate the arrhythmia...
May 11, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28502872/the-subcutaneous-icd-post-market-approval-study-clinical-characteristic-and-perioperative-results
#8
Michael R Gold, Johan D Aasbo, Mikhael F El-Chami, Mark Niebauer, John Herre, Jordan M Prutkin, Bradley P Knight, Steven Kutalek, Kevin Hsu, Raul Weiss, Eric Bass, Michael Husby, Timothy M Stivland, Martin C Burke
BACKGROUND: The subcutaneous implantable defibrillator (S-ICD) was developed to reduce short and long-term complications associated with transvenous ICD (TV-ICD) leads. Early multicenter studies included younger patients with less LV systolic dysfunction and fewer comorbidities than traditional ICD cohorts. OBJECTIVE: To characterize patient selection and the acute performance of the S-ICD in a contemporary real world setting. METHODS: The S-ICD PAS is a prospective registry involving 86 US centers...
May 11, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28502871/a-leadless-pacemaker-in-the-real-world-setting-the-micra-transcatheter-pacing-system-post-approval-registry
#9
Paul R Roberts, Nicolas Clementy, Faisal Al Samadi, Christophe Garweg, Jose Luis Martinez-Sande, Saverio Iacopino, Jens Brock Johansen, Xavier Vinolas Prat, Robert Kowal, Didier Klug, Lluis Mont, Jan Steffel, Shelby Li, Dirk Van Osch, Mikhael F El-Chami
BACKGROUND: First-in-man studies of leadless pacemakers have demonstrated high implant success rates, and safety and efficacy objectives were achieved. Outside of the investigational setting, there are particular concerns over cardiac effusion/perforation, device dislodgement, infection, telemetry, and battery issues. OBJECTIVE: The acute performance of the Micra transcatheter pacemaker from a worldwide post-approval registry is reported. METHODS: The registry is an ongoing prospective single-arm observational study designed to assess the safety and effectiveness of Micra in the post-approval setting...
May 11, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28502870/comparison-of-longevity-and-clinical-outcomes-of-implantable-cardioverter-defibrillator-leads-among-manufactures
#10
Satoshi Kawada, Nobuhiro Nishii, Yoshimasa Morimoto, Akihito Miyoshi, Motomi Tachibana, Hiroyasu Sugiyama, Koji Nakagawa, Atsuyuki Watanabe, Hiroshi Morita, Hiroshi Ito
BACKGROUND: An early failure of the Biotronik Linox S/SD implantable cardioverter defibrillator (ICD) lead has been reported. We have also experienced several cases with early failure of Linox leads. OBJECTIVE: Our aim was to assess the longevity of Linox S/SD compared to Sprint Fidelis, Sprint Quattro and Endotak Reliance leads. METHODS: We retrospectively reviewed patients who had undergone implantation of Linox S/SD (n=90), Sprint Fidelis (n=37), Sprint Quattro (n=27) or Endotak Reliance (n=50) leads between June 2000 and December 2013 at our hospital...
May 11, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28502708/2017-hrs-expert-consensus-statement-on-magnetic-resonance-imaging-and-radiation-exposure-in-patients-with-cardiovascular-implantable-electronic-devices
#11
Julia H Indik, J Rod Gimbel, Haruhiko Abe, Ricardo Alkmim-Teixeira, Ulrika Birgersdotter-Green, Geoffrey D Clarke, Timm-Michael L Dickfeld, Jerry W Froelich, Jonathan Grant, David L Hayes, Hein Heidbuchel, Salim F Idriss, Emanuel Kanal, Rachel Lampert, Christian E Machado, John M Mandrola, Saman Nazarian, Kristen K Patton, Marc A Rozner, Robert J Russo, Win-Kuang Shen, Jerold S Shinbane, Wee Siong Teo, William Uribe, Atul Verma, Bruce L Wilkoff, Pamela K Woodard
No abstract text is available yet for this article.
May 10, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28506919/novel-dye-less-and-fluoro-less-approach-to-cryoballoon-pulmonary-vein-occlusion-assessment
#12
Boaz Avitall, Arthur Kalinski, G Stephen Kocheril, Timothy G Laske, Nicolas Coulombe
BACKGROUND: Occlusion of pulmonary veins is essential for PV isolation using the Cryo balloon. Currently occlusion is arbitrarily determined using fluoroscopy and contrast media. This study aimed to create an objective measure without utilizing excessive fluoroscopy and no contrast media. OBJECTIVE: Ensure PV occlusion without fluoroscopy and contrast dye. METHODS: In 4 in vivo hearts 113 PV occlusions were tested with a 50% cold dye saline mix at 4°C...
May 8, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28506914/compliant-endovascular-balloon-reduces-the-lethality-of-superior-vena-cava-tears-during-transvenous-lead-extractions
#13
Ryan Azarrafiy, Darren C Tsang, Thomas A Boyle, Bruce L Wilkoff, Roger G Carrillo
BACKGROUND: Superior vena cava (SVC) lacerations have been identified as the most lethal complication encountered during cardiac-implantable electronic device lead extraction. The case fatality rate of these events approximate 50% due to rapid exsanguination. A novel, compliant balloon specifically designed for use in the SVC may provide hemostasis in the event of endovascular perforation. By temporarily occluding the compromised vessel, the endovascular balloon should delay hemodynamic collapse, provide a more controlled surgical field for repair, and thereby reduce the mortality of SVC tears complicating transvenous lead extraction...
May 8, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28495655/increased-sodium-calcium-exchanger-activity-enhances-beta-adrenergic-mediated-increase-in-heart-rate-whole-heart-study-in-a-homozygous-sodium-calcium-exchanger-overexpressor-mouse-model
#14
Sven Kaese, Nils Bögeholz, Paul Pauls, Dirk Dechering, Jan Olligs, Katharina Kölker, Sascha Badawi, Gerrit Frommeyer, Christian Pott, Lars Eckardt
BACKGROUND: The cardiac Na(+)/Ca(2+)-exchanger (NCX) contributes to diastolic depolarization in cardiac pacemaker cells. Increased NCX activity has been found in heart failure and atrial fibrillation. So far, the influence of increased NCX activity on resting heart rate, beta-adrenergic mediated increase in heart rate and cardiac conduction properties is unknown. OBJECTIVE: This study therefore investigates the influence of NCX overexpression in a homozygous transgenic whole-heart mouse model (NCX-OE) on sinus and AV nodal function...
May 8, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28495654/minimally-invasive-surgical-ablation-should-we-ablate-harder-or-smarter
#15
EDITORIAL
David Callans, Ramanan Kumareswaran
No abstract text is available yet for this article.
May 8, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28495653/in-search-of-the-holy-grail-in-the-channelopathy-field-proving-pathogenicity-of-long-qt-syndrome-associated-variants
#16
EDITORIAL
Arthur A M Wilde, Christopher Semsarian
No abstract text is available yet for this article.
May 8, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28495652/acute-efficacy-safety-and-long-term-clinical-outcomes-utilizing-the-second-generation-cryoballoon-for-pulmonary-vein-isolation-in-patients-with-a-left-common-pulmonary-vein-a-multicenter-study
#17
Christian-Hendrik Heeger, Verena Tscholl, Erik Wissner, Thomas Fink, Laura Rottner, Peter Wohlmuth, Barbara Bellmann, Mattias Roser, Shibu Mathew, Christian Sohns, Bruno Reißmann, Christine Lemeš, Tilman Maurer, Francesco Santoro, Johannes Riedl, Britta Goldmann, Ulf Landmesser, Feifan Ouyang, Karl-Heinz Kuck, Andreas Rillig, Andreas Metzner
BACKGROUND: Second-generation cryoballoon (CB2)-based pulmonary vein isolation (PVI) has demonstrated encouraging clinical results in the treatment of paroxysmal (PAF) and persistent atrial fibrillation (PersAF). However, the CB2 features a maximal diameter of 28mm and its adaptability to anatomical variations of the pulmonary veins (PVs) might be challenging. OBJECTIVE: To assess acute efficacy, safety and long-term clinical results of CB2-based PVI in patients with a left common PV (LCPV)...
May 8, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28495651/percentile-categorization-of-qt-interval-as-an-approach-for-identifying-adult-patients-at-risk-for-cardiovascular-death
#18
Reza Mohebi, Ayesha Jehan, Aaron Grober, Victor Froelicher
BACKGROUND: The results from studies of the association of QT prolongation with CVD have been inconsistent. OBJECTIVES: To compare the major correction formulas to percentile values of QT for heart rate ranges as to their ability to remove the relationship of QT to heart rate and to predict cardiovascular death(CVD). METHODS: Participants were 16,531 veterans who had an initial ECG at the Veterans Affairs Medical Center, Palo Alto between March 31, 1987, and December 20, 1999 and were followed for CVD...
May 8, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28495301/2017-ishne-hrs-expert-consensus-statement-on-ambulatory-ecg-and-external-cardiac-monitoring-telemetry
#19
Jonathan S Steinberg, Niraj Varma, Iwona Cygankiewicz, Peter Aziz, Paweł Balsam, Adrian Baranchuk, Daniel J Cantillon, Polychronis Dilaveris, Sergio J Dubner, Nabil El-Sherif, Jaroslaw Krol, Malgorzata Kurpesa, Maria Teresa La Rovere, Suave S Lobodzinski, Emanuela T Locati, Suneet Mittal, Brian Olshansky, Ewa Piotrowicz, Leslie Saxon, Peter H Stone, Larisa Tereshchenko, Gioia Turitto, Neil J Wimmer, Richard L Verrier, Wojciech Zareba, Ryszard Piotrowicz
Ambulatory ECG (AECG) is very commonly employed in a variety of clinical contexts to detect cardiac arrhythmias and/or arrhythmia patterns which are not readily obtained from the standard ECG. Accurate and timely characterization of arrhythmias is crucial to direct therapies that can have an important impact on diagnosis, prognosis or patient symptom status. The rhythm information derived from the large variety of AECG recording systems can often lead to appropriate and patient-specific medical and interventional management...
May 4, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28479516/risk-model-for-predicting-complications-in-patients-undergoing-atrial-fibrillation-ablation-short-title-risk-score-for-predicting-atrial-fibrillation-ablation-complications
#20
Santosh K Padala, Sampath Gunda, Parikshit S Sharma, Le Kang, Jayanthi N Koneru, Kenneth A Ellenbogen
BACKGROUND: Predictors of complications from AF ablation have been identified in small studies. The combination of risk factors to predict complications after ablation has not yet been explored. OBJECTIVE: To develop a risk score model that predicts complications after AF ablation. METHODS: The National Inpatient Sample database was utilized to identify 106,105 patients who underwent AF ablation. The study population was split into derivation cohort (DC, 2007-2010, n= 56,658) and validation cohort (VC, 2011-2013, n= 49,447)...
May 4, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
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