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Heart Rhythm: the Official Journal of the Heart Rhythm Society

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https://www.readbyqxmd.com/read/28919378/sudden-death-mechanisms-in-non-ischemic-cardiomyopathies-insights-gleaned-from-clinical-implantable-cardioverter-defibrillator-trials
#1
Benjamin A Steinberg, Siva K Mulpuru, James C Fang, Bernard J Gersh
Sudden cardiac death (SCD) represents a major cause of death among patients with heart failure. While scar-based, macro-reentrant ventricular tachycardia and ventricular fibrillation (VT/VF) is the primary etiology for SCD among patients with ischemic cardiomyopathy, a more diverse set of mechanisms and substrates are likely at play for the diverse group of patients characterized by non-ischemic, dilated cardiomyopathy (NICM). These causes may include scar-based re-entry, but also neurohormonal stimulation (sympathetic, parasympathetic, renin-angiotensin-aldosterone), inflammation, and non-arrhythmic processes occurring in the context of a genetic predisposition...
September 14, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917568/contact-force-sensing-catheters-and-increased-risk-of-atrioesophageal-fistula-is-the-tool-to-blame-or-the-workmen
#2
LETTER
Moloy Das, David R Tomlinson, Dhiraj Gupta
No abstract text is available yet for this article.
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917567/pulmonary-sinus-of-valsalva-arrhythmias-a-new-twist-to-an-old-story
#3
EDITORIAL
Henry H Hsia, Melvin Scheinman
No abstract text is available yet for this article.
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917566/out-of-hospital-cardiac-arrest-due-to-ventricular-fibrillation-in-children-a-call-to-action
#4
EDITORIAL
Sarah R Fuchs, Prince J Kannankeril
No abstract text is available yet for this article.
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917565/author-s-reply-to-contact-force-sensing-catheters-and-increased-risk-of-atrioesophageal-fistula-is-the-tool-to-blame-or-the-workmen
#5
LETTER
Eric Black-Maier, Jonathan P Piccini
No abstract text is available yet for this article.
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917564/impact-of-institutional-procedural-volume-on-in-hospital-outcomes-after-cardiac-resynchronization-therapy-device-implantation-united-states-national-database-2003-2011
#6
Ilhwan Yeo, Luke K Kim, Bruce B Lerman, Jim W Cheung
BACKGROUND: The relationship between hospital volume and outcomes for cardiac resynchronization therapy (CRT) implantations has not been well established. OBJECTIVES: To examine outcomes after CRT device implantation stratified on hospital volume based on a large, national inpatient database. METHODS: Using the National Inpatient Sample database, we identified all patients undergoing de novo CRT implants between 2003 and 2011. Hospitals were categorized according to tertiles of annual CRT procedural volume...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917563/ligament-of-marshall-arrhythmogenesis-and-vein-of-marshall-ethanol-a-problem-with-a-solution
#7
EDITORIAL
Miguel Valderrábano
No abstract text is available yet for this article.
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917562/an-updated-meta-analysis-of-novel-oral-anticoagulants-versus-vitamin-k-antagonists-for-uninterrupted-anticoagulation-in-atrial-fibrillation-catheter-ablation
#8
Rhanderson Cardoso, Leonardo Knijnik, Aditya Bhonsale, Guilherme Nasi, Manuel Rivera, Vanessa Blumer, Hugh Calkins
BACKGROUND: Catheter ablation is recommended as a first or second-line rhythm control therapy for selected patients with atrial fibrillation (AF). There is a wide variability in the periprocedural management of oral anticoagulation for patients undergoing AF ablation. OBJECTIVE: We aimed to perform an updated meta-analysis of novel oral anticoagulants (NOACs) vs. vitamin K antagonists (VKAs) as uninterrupted anticoagulation for patients undergoing AF ablation. METHODS: Databases and conference abstracts were searched...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917561/cardiac-rhythm-analysis-during-ongoing-cardiopulmonary-resuscitation-using-the-analysis-during-compressions-with-fast-reconfirmation-adc-fr-technology
#9
Francesca Fumagalli, Annemarie E Silver, Qing Tan, Naveed Zaidi, Giuseppe Ristagno
BACKGROUND: Pauses in chest compressions (CCs) have a negative association with survival from cardiac arrest (CA). ECG rhythm analysis and defibrillator charging are significant contributors to CC pauses. OBJECTIVE: Accuracy of the "Analysis During Compressions with Fast Reconfirmation" (ADC-FR) algorithm, which features automated rhythm analysis and charging during CCs to reduce CC pauses, was retrospectively determined in a large database of ECGs from 2,701 out-of-hospital CAs...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917560/outcomes-of-rescue-cardiopulmonary-support-for-periprocedural-acute-hemodynamic-decompensation-in-patients-undergoing-catheter-ablation-of-electrical-storm
#10
Andres Enriquez, Jackson Liang, Javier Gentile, Robert Schaller, Gregory Supple, David S Frankel, Fermin Garcia, Joyce Wald, Edo Y Birati, J Eduardo Rame, Christian Bermudez, David Callans, Francis Marchlinski, Pasquale Santangeli
BACKGROUND: In patients with ventricular tachycardia/fibrillation (VT/VF) electrical storm (ES) undergoing catheter ablation (CA), hypotension due to refractory VT/VF, use of anesthesia and cardiac stunning due to repeated ICD shocks might precipitate acute hemodynamic decompensation (AHD). OBJECTIVE: We evaluated the outcomes of emergent cardiopulmonary support with extracorporeal membrane oxygenation (ECMO) to rescue AHD in patients undergoing CA of ES. METHODS: Between 2010 and 2016, 21 patients with ES (VT in 11 and PVC-triggered VF in 10) were referred for CA and had periprocedural AHD requiring emergent ECMO support...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917559/predictors-and-outcomes-of-cardiac-resynchronization-therapy-extended-to-the-second-generator
#11
Xuping Li, Dachun Yang, Fred Kusumoto, Win-Guang Shen, Siva Mulpuru, Shenghua Zhou, Jinjun Liang, Gang Wu, Mei Yang, Jin-Qu Liu, Paul A Friedman, Yong-Mei Cha
BACKGROUND: A proportion of patients who receive cardiac resynchronization therapy (CRT) with defibrillator (CRT-D) live to receive a second generator. Controversy exists on whether an implantable cardioverter-defibrillator (ICD) should be offered to patients who have normalized or near normalized left ventricular ejection fraction (LVEF) at the time of generator replacement (GR). OBJECTIVE: To evaluate incidence of appropriate ICD therapy after CRT-D GR. METHODS: This series involved 1,026 consecutive patients who underwent CRT-D implant between January 2002 and December 2012...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917558/cardiac-sympathectomy-for-the-management-of-ventricular-arrhythmias-refractory-to-catheter-ablation
#12
Travis Richardson, Ricardo Lugo, Pablo Saavedra, George Crossley, Walter Clair, Sharon Shen, Juan Carlos Estrada, Jay Montgomery, M Benjamin Shoemaker, Christopher Ellis, Gregory F Michaud, Eric Lambright, Arvindh Kanagasundram
BACKGROUND: Catheter ablation is now a mainstay of therapy for ventricular arrhythmias (VA). However, there are scenarios where either physiologic or anatomical factors make ablation less likely to be successful. OBJECTIVES: To demonstrate that cardiac sympathetic denervation (CSD) may be an alternate therapy for patients with difficult to ablate VA. METHODS: We identified all patients referred for CSD at a single center for indications other than LQTS and CPVT who had failed catheter ablation...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917557/idiopathic-ventricular-arrhythmias-originating-from-the-right-coronary-sinus-prevalence-electrocardiographic-and-electrophysiologic-characteristics-and-catheter-ablation
#13
Yunlong Wang, Zhuo Liang, Shaoqin Wu, Zhihong Han, Xuejun Ren
BACKGROUND: Ventricular arrhythmias (VAs) of right coronary cusp (RCC) are not fully characterized. OBJECTIVES: To investigate the electrocardiographic and electrophysiologic characteristics, mapping and ablation of RCC-VAs. METHODS: Among 256 consecutive patients undergoing electrophysiologic evaluation and ablation of VAs of ventricular outflow tract origin, data were compared among 27 RCC-VAs, 50 VAs of the septal aspect of right ventricular outflow tract (RVOT, including from pulmonary artery) and 9 VAs of left coronary cusp (LCC)...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917556/increased-risk-of-ventricular-arrhythmias-in-survivors-of-out-of-hospital-cardiac-arrest-with-chronic-total-coronary-occlusion
#14
Sing-Chien Yap, Rafi Sakhi, Dominic Amj Theuns, Yunus E Yasar, Rohit E Bhagwandien, Roberto Diletti, Felix Zijlstra, Tamas Szili-Torok
BACKGROUND: A chronic total occlusion (CTO) is common in out-of-hospital cardiac arrest (OHCA) survivors with coronary artery disease. It is unclear whether a CTO contributes to ventricular arrhythmias in this population. OBJECTIVE: This study sought to evaluate the impact of unrevascularized CTO's on the occurrence of appropriate implantable cardioverter-defibrillator (ICD) therapy and all-cause mortality in OHCA survivors with coronary artery disease. METHODS: This was a retrospective study that included all consecutive OHCA survivors with coronary artery disease who received an ICD from 1999 until 2015...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917555/incidence-and-significance-of-adhesions-encountered-during-epicardial-mapping-and-ablation-of-ventricular-tachycardia-in-patients-with-no-history-of-prior-cardiac-surgery-or-pericarditis
#15
Anthony Li, Eric Buch, Noel G Boyle, Kalyanam Shivkumar, Jason S Bradfield
BACKGROUND: Pericardial adhesions can prevent epicardial access and restrict catheter movement during mapping and ablation of ventricular tachycardia (VT) . The incidence of adhesions in patients without prior cardiac surgery or clinically evident pericarditis is not known. OBJECTIVE: To describe the incidence of pericardial adhesions in patients without prior cardiac surgery or pericarditis and explore their impact. METHODS: A retrospective search of our ablation database containing patients who underwent epicardial ablation for VT was undertaken...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917554/founder-populations-with-channelopathies-and-church-records-reveal-all-sorts-of-interesting-secrets-some-are-scientifically-relevant
#16
EDITORIAL
Peter J Schwartz, Lia Crotti
No abstract text is available yet for this article.
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917553/absence-of-rotational-activity-detected-using-two-dimensional-phase-mapping-in-corresponding-three-dimensional-phase-maps-in-human-persistent-atrial-fibrillation
#17
Bhupesh Pathik, Jonathan M Kalman, Tomos Walters, Pawel Kuklik, Jichao Zhao, Andrew Madry, Prashanthan Sanders, Peter M Kistler, Geoffrey Lee
BACKGROUND: Current phase mapping systems for atrial fibrillation(AF) create two-dimensional(2D) maps. This process may affect the accurate detection of rotors. We developed a three-dimensional(3D) phase mapping technique that utilizes the 3D locations of basket electrodes to project phase onto patient-specific left atrial(LA) 3D surface anatomy. OBJECTIVES: We sought to determine whether rotors detected in 2D phase maps were present at corresponding time segments and anatomical locations on 3D phase maps...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28917552/crispr-correction-of-the-prkag2-gene-mutation-in-the-patient-s-ipsc-derived-cardiomyocytes-eliminates-the-electrophysiological-and-structural-abnormalities
#18
Ronen Ben Jehuda, Binyamin Eisen, Yuval Shemer, Lucy N Mekies, Agnes Szantai, Irina Reiter, Huanhuan Cui, Kaomei Guan, Shiraz Haron-Khun, Dov Freimark, Silke R Sperling, Mihaela Gherghiceanu, Michael Arad, Ofer Binah
BACKGROUND: Mutations in the PRKAG2 gene encoding the γ-subunit of adenosine monophosphate-kinase (AMPK) cause hypertrophic cardiomyopathy (HCM) and familial-Wolff-Parkinson-White syndrome (WPW). Patients carrying the R302Q mutation in PRKAG2 present sinus bradycardia, escape rhythms, ventricular pre-excitation, supraventricular tachycardia and atrioventricular block. This mutation affects AMPK activity and increases glycogen storage in cardiomyocytes. The link between glycogen storage, WPW, HCM and arrhythmias remains unknown...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28919290/utility-and-limitations-of-long-term-monitoring-of-atrial-fibrillation-using-an-implantable-loop-recorder
#19
Randall Lee, Suneet Mittal
Atrial fibrillation (AF) is the most common cardiac arrhythmia diagnosed and treated in the world. The treatment of patients' symptoms as well as the prevention of stroke and heart failure is dependent on accurate detection and characterization of AF. A variety of electrocardiographic (ECG) monitoring techniques are being used for these purposes. However, these intermittent ECG monitoring techniques have been shown to under diagnose AF events, while having limited ability to characterize AF burden and density...
September 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28919379/2017-hrs-expert-consensus-statement-on-cardiovascular-implantable-electronic-device-lead-management-and-extraction
#20
Fred M Kusumoto, Mark H Schoenfeld, Bruce L Wilkoff, Charles I Berul, Ulrika M Birgersdotter-Green, Roger Carrillo, Yong-Mei Cha, Jude Clancy, Jean-Claude Deharo, Kenneth A Ellenbogen, Derek Exner, Ayman A Hussein, Charles Kennergren, Andrew Krahn, Richard Lee, Charles J Love, Ruth A Madden, Hector Alfredo Mazzetti, JoEllyn Carol Moore, Jeffrey Parsonnet, Kristen K Patton, Marc A Rozner, Kimberly A Selzman, Morio Shoda, Komandoor Srivathsan, Neil F Strathmore, Charles D Swerdlow, Christine Tompkins, Oussama Wazni
No abstract text is available yet for this article.
September 11, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
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