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Heart Rhythm: the Official Journal of the Heart Rhythm Society

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https://www.readbyqxmd.com/read/28232263/progression-of-paroxysmal-to-persistent-atrial-fibrillation-canadian-registry-of-atrial-fibrillation-10-year-follow-up
#1
Gareth J Padfield, Christian Steinberg, Janice Swampillai, Hong Qian, Stuart J Connolly, Paul Dorian, Martin S Green, Karin H Humphries, George J Klein, Robert Sheldon, Mario Talajic, Charles R Kerr
BACKGROUND: Progression from paroxysmal to persistent atrial fibrillation (AF) has important clinical implications and is relevant to the management of patients with AF. OBJECTIVES: To define the long-term rate of progression from paroxysmal to persistent AF and the relevant clinical variables. METHODS: The Canadian Registry of Atrial Fibrillation (CARAF), enrolled patients following a first electrocardiographic diagnosis of paroxysmal AF...
February 20, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28232262/prevalence-predictors-and-outcomes-of-advance-directives-in-implantable-cardioverter-defibrillator-recipients
#2
Faisal M Merchant, Zachary Binney, Adarsh Patel, Jennifer Li, Lakshmi P Peddareddy, Mikhael F El-Chami, Angel R Leon, Tammie Quest
BACKGROUND: Little is known about advance directive (AD) utilization among implantable cardioverter defibrillator (ICD) recipients. OBJECTIVE: To define prevalence and predictors of ADs among patients with ICDs METHODS: We identified ICD recipients with ADs at our institution. The primary endpoint was the prevalence of an AD documented up to 1 year after device implant and the secondary endpoint was the cumulative prevalence of an AD. RESULTS: Out of 2,549 patients with ICDs, 701 were followed for at least one year after device implant and among them 164 (23...
February 20, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28232261/the-impact-of-obesity-on-atrial-fibrillation-ablation-patient-characteristics-long-term-outcomes-and-complications
#3
Roger A Winkle, R Hardwin Mead, Gregory Engel, Melissa H Kong, William Fleming, Jonathan Salcedo, Rob A Patrawala
BACKGROUND: There is an association between obesity and atrial fibrillation(AF). The impact of obesity on AF ablations is unclear. OBJECTIVES: To evaluate the influence of Body Mass Index(BMI) on patient characteristics, long-term ablation outcomes and procedural complications. METHODS: We evaluated 2715 patients undergoing 3742 AF ablations. BMI was ≥30 in 1058(39%) and ≥40 in 129(4.8%). Patients were grouped by BMI ranges(<25,25-<30,30-<35,35-<40,>40)...
February 20, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28223192/editorial-commentary-anticoagulation-for-atrial-fibrillation-in-dialysis-patients-what-is-known-and-what-does-the-future-hold
#4
EDITORIAL
Timothy M Markman, Saman Nazarian
No abstract text is available yet for this article.
February 18, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28223191/interleukin-1-receptor-inhibition-dampens-the-flame-of-post-infarction-arrhythmias
#5
EDITORIAL
Matthew Kay
No abstract text is available yet for this article.
February 18, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28219848/bioelectronic-neuromodulation-of-the-paravertebral-cardiac-efferent-sympathetic-outflow-and-its-effect-on-ventricular-electrical-indices
#6
Una Buckley, Ray W Chui, Pradeep S Rajendran, Tina Vrabec, Kalyanam Shivkumar, Jeffrey L Ardell
INTRODUCTION: Neuromodulation of the paravertebral ganglia, using symmetric voltage controlled kilohertz frequency alternating current (KHFAC), has the potential to be a reversible alternative to surgical intervention in patients with refractory ventricular arrhythmias. KHFAC creates scalable focal inhibition of action potential conduction. OBJECTIVE: To evaluate the efficacy of KHFAC, when applied to T1-T2 paravertebral chain, to mitigate sympathetic outflow to the heart...
February 17, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28214567/fluoroless-catheter-ablation-of-atrial-fibrillation
#7
Bruce B Lerman, Steven M Markowitz, Christopher F Liu, George Thomas, James Ip, Jim Cheung
No abstract text is available yet for this article.
February 15, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28214566/electrophysiology-testing-and-pacing-in-octogenarians-with-unexplained-syncope-time-to-reconsider
#8
EDITORIAL
Peter Santucci
No abstract text is available yet for this article.
February 15, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28214565/trends-and-outcomes-of-cardiac-resynchronization-therapy-upgrade-procedures-a-comparative-analysis-using-a-united-states-national-database-2003-2013
#9
Jim W Cheung, James E Ip, Steven M Markowitz, Christopher F Liu, George Thomas, Dmitriy N Feldman, Rajesh V Swaminathan, Bruce B Lerman, Luke K Kim
BACKGROUND: While outcomes after de novo CRT implantations have been reported, there are limited data on CRT upgrade procedures. OBJECTIVES: The purpose of this study to examine trends and in-hospital outcomes of patients undergoing upgrade to cardiac resynchronization therapy (CRT) procedures using a large, national inpatient database. METHODS: Using the National Inpatient Sample database, we identified all patients undergoing CRT upgrade and de novo CRT implants between 2003 and 2013...
February 15, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28213056/balloon-tamponade-of-the-svc-and-the-management-of-catastrophic-complications-of-cardiac-lead-extraction
#10
EDITORIAL
Matthew S Baker, J Paul Mounsey
No abstract text is available yet for this article.
February 14, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28213055/electrophysiological-measurements-that-can-explain-and-guide-temporary-accelerated-pacing-to-avert-re-occurrence-of-torsade-de-pointes-arrhythmias-in-the-canine-chronic-atrioventricular-block-model
#11
Sofieke C Wijers, Alexandre Bossu, Albert Dunnink, Jet D M Beekman, Rosanne Varkevisser, Alfonso Aranda Hernández, Mathias Meine, Marc A Vos
BACKGROUND: Pacing at higher rates is known to suppress Torsade de Pointes (TdP) arrhythmias. Nevertheless, exact application and mechanism need further clarification. In the anesthetized, canine, chronic atrioventricular block model, ventricular remodeling is responsible for a high and reproducible incidence of TdP upon a challenge with dofetilide. OBJECTIVE: We used this model to investigate by what mechanism accelerated pacing averts TdP and what repolarization parameter could be used to guide temporary applied accelerated pacing (TAP)...
February 14, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28213054/commentary-clinical-phenotype-of-hcn4-related-sick-sinus-syndrome
#12
EDITORIAL
Frank J Raucci, M Benjamin Shoemaker, Bjorn C Knollmann
No abstract text is available yet for this article.
February 14, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28189825/predictors-and-outcomes-of-lead-extraction-requiring-a-bailout-femoral-approach-data-from-2-high-volume-centers
#13
Mikhael F El-Chami, Faisal Merchant, Anam Waheed, Furqan Khattak, Jad El-Khalil, Adarsh Patel, Michael N Sayegh, Yaanik Desai, Angel R Leon, Samir Saba
BACKGROUND: Lead extraction (LE) infrequently requires the use of the "bailout" femoral approach. Predictors and outcomes of femoral extraction are not well characterized. OBJECTIVE: The aim of this study was to determine the predictors of need for femoral LE and its outcomes. METHODS: Consecutive patients who underwent LE at our centers were identified. Baseline demographic characteristics, procedural outcomes, and clinical outcomes were ascertained by medical record review...
February 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28215570/the-cardiac-electrophysiology-of-patients-with-spinal-cord-injury
#14
Michael Manogue, David S Hirsh, Michael Lloyd
Spinal cord injury (SCI) is a clinical syndrome encountered frequently in trauma centers and is accompanied by both acute and chronic heart rhythm abnormalities. The injury is characterized by sympathetic nervous system (SNS) impairment with preservation of parasympathetic output via the vagus nerve. Severe bradycardia in the form of life-threatening sinus arrest or complete heart block may be observed in the acute recovery phase. Therapy for arrhythmias in the acute phase includes atropine, intravenous chronotropes, methylxanthines for prevention of episodic bradycardia, and pacemaker implantation in severe cases...
February 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28215569/cardiac-phenotype-and-long-term-prognosis-of-arrhythmogenic-right-ventricular-cardiomyopathy-dysplasia-patients-with-late-presentation
#15
Aditya Bhonsale, Anneline S J M Te Riele, Abhishek C Sawant, Judith A Groeneweg, Cynthia A James, Brittney Murray, Crystal Tichnell, Thomas P Mast, Michelle J van der Pols, Maarten J M Cramer, Dennis Dooijes, Jeroen F van der Heijden, Harikrishna Tandri, J Peter van Tintelen, Daniel P Judge, Richard N W Hauer, Hugh Calkins
BACKGROUND: The clinical profile of Arrhythmogenic Right Ventricular Cardiomyopathy/ Dysplasia patients with late presentation (ARVC/D) is unknown. OBJECTIVE: To characterize the genotype, cardiac phenotype and long term outcomes of ARVC/D patients with late presentation (age≥ 50 years at diagnosis) METHODS: 502 patients with ARVC/D diagnosis from Johns Hopkins and Utrecht registries were studied and long term clinical outcomes ascertained. RESULTS: Late presentation was seen in 104 (21%) patients (38% PKP2 carriers) with 3% ≥ 65 years at diagnosis...
February 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28215568/reduction-in-radiation-dose-for-atrial-fibrillation-ablation-over-time-a-12-year-single-centre-experience-of-2-344-patients
#16
Aleksandr Voskoboinik, Elana S Kalman, Yonatan Savicky, Paul B Sparks, Joseph B Morton, Geoffrey Lee, Peter M Kistler, Jonathan M Kalman
BACKGROUND: Pulmonary vein isolation (PVI) is a well-established treatment for atrial fibrillation (AF), with contact force-sensing catheters joining 3D-mapping systems and image integration as technological advancements over the last decade. OBJECTIVE: To analyze trends in radiation exposure at our centre for AF ablation over the last 12 years. METHODS: We reviewed prospectively collected data of 2,344 consecutive PVI procedures for either paroxysmal or persistent AF between 1/2004 - 12/2015...
February 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28193509/pilot-study-analyzing-automated-ecg-screening-of-hypertrophic-cardiomyopathy
#17
Matthew Campbell, Xuefu Zhou, Chia Han, Hedayat Abrishami, Gregory Webster, Christina Y Miyake, Christopher T Sower, Jeffery B Anderson, Timothy K Knilans, Richard J Czosek
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is one of the leading causes of sudden cardiac death in athletes. However, pre-participation ECG screening has often been criticized for failing to meet cost-effectiveness thresholds, in part because of high false-positive rates and the cost of ECG screening itself. OBJECTIVES: To assess the testing characteristics of an automated ECG algorithm designed to screen for HCM in a multi-institutional pediatric cohort. METHODS: ECGs from patients with HCM aged 12 - 20 years from 3 pediatric institutions were screened for ECG criteria for HCM using a previously described automated computer algorithm developed specifically for HCM ECG screening...
February 10, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28193508/renal-sympathetic-stimulation-and-ablation-affect-ventricular-arrhythmia-by-modulating-autonomic-activity-in-a-cesium-induced-long-qt-canine-model
#18
Lilei Yu, Bing Huang, Xiaoya Zhou, Songyun Wang, Zhuo Wang, Menglong Wang, Xuefei Li, Liping Zhou, Guannan Meng, Shenxu Yuan, Yuhong Wang, Hong Jiang
BACKGROUND: Our previous studies have shown that renal sympathetic stimulation (RS) may facilitate ischemic ventricular arrhythmia (VA) by increasing left stellate ganglion (LSG) nerve activity, while renal sympathetic ablation (RA) may suppress VA. OBJECTIVE: This study aimed to investigate whether renal sympathetic interventions could also affect VA by modulating LSG activity in a cesium-induced long QT canine model. METHODS: Twenty-four dogs were randomly divided into RS group (n=8), RA group (n=8), and control group (n=8)...
February 10, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28192209/a-new-alara-keeping-leadless-pacing-thresholds-as-low-as-reasonably-achievable
#19
EDITORIAL
Joseph E Marine
No abstract text is available yet for this article.
February 10, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28192207/long-term-performance-of-a-transcatheter-pacing-system-12-month-results-from-the-micra-transcatheter-pacing-study
#20
Gabor Z Duray, Philippe Ritter, Mikhael El-Chami, Calambur Narasimhan, Razali Omar, Jose M Tolosana, Shu Zhang, Kyoko Soejima, Clemens Steinwender, Leonardo Rapallini, Aida Cicic, Dedra H Fagan, Shufeng Liu, Dwight Reynolds
BACKGROUND: Early performance of the Micra transcatheter pacemaker from the global clinical trial reported a 99.2% implant success rate, low and stable pacing capture thresholds, and a low (4.0%) rate of major complications up to 6 months. OBJECTIVE: The purpose of this report was to describe the prespecified long-term safety objective of Micra at 12 months and electrical performance through 24 months. METHODS: The Micra Transcatheter Pacing Study was a prospective single-arm study designed to assess the safety and efficacy of the Micra VVIR leadless/intracardiac pacemaker...
February 10, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
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