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Chronic Respiratory Disease

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https://www.readbyqxmd.com/read/29117798/inflammatory-biomarkers-and-radiologic-measurements-in-never-smokers-with-copd-a-cross-sectional-study-from-the-coda-cohort
#1
Hyun Lee, Yoonki Hong, Myoung Nam Lim, So Hyeon Bak, Min-Ji Kim, Kyunga Kim, Woo Jin Kim, Hye Yun Park
Various biomarkers have emerged as potential surrogates to represent various subgroups of chronic obstructive pulmonary disease (COPD), which manifest with different phenotypes. However, the biomarkers representing never-smokers with COPD have not yet been well elucidated. The aim of this study was to evaluate the associations of certain serum and radiological biomarkers with the presence of COPD in never-smokers. To explore the associations of serum and radiological biomarkers with the presence of COPD in never-smokers, we conducted a cross-sectional patient cohort study composed of never-smokers from the COPD in Dusty Areas (CODA) cohort, consisting of subjects living in dusty areas near cement plants in South Korea...
May 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/29117797/obesity-and-metabolic-syndrome-in-copd-is-exercise-the-answer
#2
Benjamin D James, Amy V Jones, Ruth E Trethewey, Rachael A Evans
Approximately half of all patients with chronic obstructive pulmonary disease (COPD) attending pulmonary rehabilitation (PR) programmes are overweight or obese which negatively impacts upon dyspnoea and exercise tolerance particularly when walking. Within the obese population (without COPD), the observed heterogeneity in prognosis is in part explained by the variability in the risk of developing cardiovascular disease or diabetes (cardiometabolic risk) leading to the description of metabolic syndrome. In obesity alone, high-intensity aerobic training can support healthy weight loss and improve the constituent components of metabolic syndrome...
May 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/29117796/effects-of-varenicline-therapy-in-combination-with-advanced-behavioral-support-on-smoking-cessation-and-quality-of-life-in-inpatients-with-acute-exacerbation-of-copd-bronchial-asthma-or-community-acquired-pneumonia-a-prospective-open-label-preference-based
#3
Alexios Politis, Vasileios Ioannidis, Konstantinos I Gourgoulianis, Zoe Daniil, Chrissi Hatzoglou
Quitting smoking is the most important element in the therapeutic management of chronic respiratory diseases. Combining pharmacotherapy with behavioral support increases smoking cessation success rates. In addition, hospitalized smokers have increased motivation to quit. We investigated the efficacy on smoking cessation, of varenicline in combination with behavioral support, in smokers hospitalized due to (a) acute exacerbation of chronic obstructive pulmonary disease (COPD), or (b) bronchial asthma attack, or (c) community-acquired pneumonia (CAP)...
May 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/29117795/high-sensitivity-cardiac-troponin-t-in-obstructive-sleep-apnea-patients-without-cardiovascular-diseases-efficacy-of-cpap-treatment
#4
Xiao-Bin Zhang, Hui-Qing Zeng, Yan-Ping Du, Zhi Lyu, Feng-Fu Zhan
The aims of this article were to determine the levels of serum high-sensitivity cardiac troponin T (hs-cTnT) in obstructive sleep apnea (OSA) patients without cardiovascular disease (CVD) and to assess the efficacy of continuous positive airway pressure (CPAP). Snorers referred for polysomnography (PSG) for the investigation of OSA were eligible and hs-cTnT levels measured in our pilot study. Hs-cTnT was measured again after 3 months of CPAP treatment in participants with severe OSA. A total of 93 participants recruited after PSG...
May 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28868892/home-based-pulmonary-rehabilitation-for-people-with-copd-a-qualitative-study-reporting-the-patient-perspective
#5
Aroub Lahham, Christine F McDonald, Ajay Mahal, Annemarie L Lee, Catherine J Hill, Angela T Burge, Narelle S Cox, Rosemary Moore, Caroline Nicolson, Paul O'Halloran, Rebecca Gillies, Anne E Holland
This study aimed to document the perspective of patients with chronic obstructive pulmonary disease (COPD) who underwent home-based pulmonary rehabilitation (HBPR) in a clinical trial. In this qualitative study, open-ended questions explored participants' views regarding HBPR. Thirteen semi-structured interviews were analysed using a thematic analysis approach. Major themes from interviews included the positive impact of HBPR on physical fitness, breathing and mood. Participants valued the flexibility and convenience of the programme...
May 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28851233/shuttle-walk-tests-in-people-with-copd-who-demonstrate-exercise-induced-oxygen-desaturation-an-analysis-of-test-repeatability-and-cardiorespiratory-responses
#6
Zoe McKeough, Regina Leung, Ji Hui Neo, Sue Jenkins, Anne Holland, Kylie Hill, Norman Morris, Lissa Spencer, Catherine Hill, Annemarie Lee, Helen Seale, Nola Cecins, Christine McDonald, Jennifer Alison
Exercise-induced oxygen desaturation (EID) is prevalent in people with chronic obstructive pulmonary disease (COPD). This article reports a sub-analysis from a randomized controlled trial (RCT) in people with COPD and EID (COPD/EID). The primary aim, in people with COPD/ EID, was to determine the repeatability of the distance and time walked in the incremental shuttle walk test (ISWT) and endurance shuttle walk test (ESWT), respectively. A secondary aim was to determine whether any participant characteristics predicted those who did not demonstrate improvements on a repeat ISWT or ESWT...
May 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28750556/the-quebec-respiratory-health-education-network-integrating-a-model-of-self-management-education-in-copd-primary-care
#7
Jean Bourbeau, Raquel Farias, Pei Zhi Li, Guylaine Gauthier, Livia Battisti, Valérie Chabot, Marie-France Beauchesne, Denis Villeneuve, Patricia Côté, Louis-Philippe Boulet
The objective of this study is to evaluate whether a chronic obstructive pulmonary disease (COPD) self-management education program with coaching of a case manager improves patient-related outcomes and leads to practice changes in primary care. COPD patients from six family medicine clinics (FMCs) participated in a 1-year educational program offered by trained case managers who focused on treatment adherence, inhaler techniques, smoking cessation, and the use of an action plan for exacerbations. Health-care utilization, health-related quality of life (HRQL), treatment adherence, inhaler technique, and COPD knowledge were assessed at each visit with validated questionnaires...
May 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28718320/oral-prednisolone-for-4-days-does-not-increase-exercise-tolerance-in-men-with-copd
#8
S L Karlsson, V Backer, Nina Skavlan Godtfredsen
One of the primary objectives in management of chronic obstructive pulmonary disease (COPD) is preventing decrease in lung function and reducing the annual number of acute exacerbations of COPD (AECOPD). An oral course of systemic corticosteroids is a commonly used treatment in AECOPD. We hypothesize that this treatment also increases exercise performance and decreases muscle fatigue. In a randomized double-blinded, parallel, placebo-controlled trial, we investigated 14 men (8 on prednisolone 37.5 mg vs. 6 on placebo) with severe and very severe COPD...
May 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28635313/reliability-and-validity-of-the-chinese-version-of-the-breathlessness-beliefs-questionnaire
#9
Qing Wu, AiMin Guo, YanWei Zhao, SiJia Li, Hui Huang
The aim of this article is to evaluate the reliability and validity of the Chinese version of the Breathlessness Beliefs Questionnaire (BBQ) for use among patients with respiratory diseases in China. The BBQ is an instrument for assessing specific dyspnoea-related fears and may have predictive value for chronic obstructive pulmonary disease outcomes beyond general anxiety measures. This instrument has not previously been translated into Chinese or tested in mainland China. This was a cross-sectional validation study with a 1-week test of reproducibility...
May 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28580854/changes-in-lower-limb-muscle-function-and-muscle-mass-following-exercise-based-interventions-in-patients-with-chronic-obstructive-pulmonary-disease-a-review-of-the-english-language-literature
#10
Jana De Brandt, Martijn A Spruit, Dominique Hansen, Frits Me Franssen, Wim Derave, Maurice Jh Sillen, Chris Burtin
Chronic obstructive pulmonary disease (COPD) patients often experience lower limb muscle dysfunction and wasting. Exercise-based training has potential to improve muscle function and mass, but literature on this topic is extensive and heterogeneous including numerous interventions and outcome measures. This review uses a detailed systematic approach to investigate the effect of this wide range of exercise-based interventions on muscle function and mass. PUBMED and PEDro databases were searched. In all, 70 studies ( n = 2504 COPD patients) that implemented an exercise-based intervention and reported muscle strength, endurance, or mass in clinically stable COPD patients were critically appraised...
May 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28553720/cognitive-impairment-and-clinical-characteristics-in-patients-with-chronic-obstructive-pulmonary-disease
#11
Fiona A H M Cleutjens, Martijn A Spruit, Rudolf W H M Ponds, Lowie E G W Vanfleteren, Frits M E Franssen, Candy Gijsen, Jeanette B Dijkstra, Emiel F M Wouters, Daisy J A Janssen
We aimed to investigate (1) the relationship between cognitive impairment (CI) and disease severity and (2) the potential differences in exercise performance, daily activities, health status, and psychological well-being between patients with and without CI. Clinically stable chronic obstructive pulmonary disease (COPD) patients, referred for pulmonary rehabilitation, underwent a neuropsychological examination. Functional exercise capacity (6-minute walk test [6MWT]), daily activities (Canadian Occupational Performance Measure [COPM]), health status (COPD Assessment Test [CAT]) and St George's Respiratory Questionnaire-COPD specific [SGRQ-C]), and psychological well-being (Hospital Anxiety and Depression Scale [HADS], Beck Depression Inventory [BDI], and Symptom Checklist 90 [SCL-90]) were compared between patients with and without CI...
May 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28534421/the-prevalence-of-chronic-obstructive-pulmonary-disease-in-hookah-smokers
#12
Mehrzad Bahtouee, Nasrollah Maleki, Fatemeh Nekouee
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Hookah smoking is growing worldwide and particularly in Iran. The aim of this study was to determine the prevalence of obstructive pulmonary dysfunction in hookah smokers. We conducted a population-based study in Bushehr Province, Iran. A total of 245 subjects aged 35 years or older who were taking hookah for at least 15 years and 245 healthy controls were enrolled in the study and spirometry was done. Statistical analyses were performed using SPSS for windows software version 19...
May 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28982256/new-models-of-care-for-respiratory-disease-a-thematic-edition
#13
Graeme Rocker, Morag Farquhar, Jennifer Verma
No abstract text is available yet for this article.
February 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28786297/telehealth-pulmonary-rehabilitation-a-review-of-the-literature-and-an-example-of-a-nationwide-initiative-to-improve-the-accessibility-of-pulmonary-rehabilitation
#14
A-M Selzler, J Wald, M Sedeno, T Jourdain, T Janaudis-Ferreira, R Goldstein, J Bourbeau, M K Stickland
Several different applications of telehealth technologies have been used in the care of respiratory patients, including telemonitoring, teleconsultations, tele-education, and telehealth-pulmonary rehabilitation (PR). Telehealth technology provides an opportunity to assist in the management of chronic respiratory diseases and improve access to PR programs. While there is inconclusive evidence as to the effectiveness of telemonitoring to reduce healthcare utilization and detection of exacerbations, teleconsultations have been shown to be an effective means to assess patients' disease prior to the initiation of PR, and telehealth PR has been shown to be as effective as institution-based PR at improving functional exercise capacity and health-related quality of life...
February 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28728429/palliative-care-for-respiratory-disease-an-education-model-of-care
#15
Brynn Bowman, Diane E Meier
That palliative care improves quality of life for seriously ill patients and their families is well known - but how can healthcare providers ensure that the palliative needs of all patients are being assessed and addressed? A growing number of curricula in core palliative care practices have been developed to ensure that clinicians from all specialties and disciplines have the necessary training to manage pain and symptoms and discuss care goals with patients and families. Through broad-based training in core palliative care skills, combined with referral to specialty palliative care for high-need patients, providers can improve quality of life for their patients with respiratory disease...
February 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28718321/breathlessness-services-as-a-new-model-of-support-for-patients-with-respiratory-disease
#16
Claudia Bausewein, Michaela Schunk, Philipp Schumacher, Julika Dittmer, Anna Bolzani, Sara Booth
The complexity of breathlessness in advanced disease requires a diversity of measures ideally tailored to the individual patient needs. 'Breathlessness services' have been systematically developed and tested to provide specific interventions and support for patients and their carers. The aim of this article is (1) to identify and describe components of breathlessness services and (2) to describe the clinical model of one specific service in more detail. This article is based on a systematic review evaluating randomized controlled trials (RCTs) and quasi-RCTs which examine the effectiveness of services aiming to improve breathlessness of patients with advanced disease...
February 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28685601/assessing-carer-needs-in-chronic-obstructive-pulmonary-disease
#17
Morag Farquhar
Informal carers play a key role in supporting patients with chronic obstructive pulmonary disease (COPD), particularly when disease is advanced. They also enable delivery of healthcare professional advice. There is a well-established impact of the caring role on carers in both the generic and COPD-specific literature. The needs of carers of patients with COPD are both generic to the caring role and disease specific. Healthcare professionals and health systems supporting patients with COPD need to actively identify and support carers...
February 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28612657/improving-care-for-advanced-copd-through-practice-change-experiences-of-participation-in-a-canadian-spread-collaborative
#18
Jennifer Y Verma, Claudia Amar, Shannon Sibbald, Graeme M Rocker
Chronic obstructive pulmonary disease (COPD) is a leading cause of death, morbidity, and health-care spending. The Halifax, Nova Scotia-based INSPIRED COPD Outreach Program™ has proved highly beneficial for patients and the health-care system. With direct investment of <$1-million CAD, a pan-Canadian quality improvement collaborative (QIC) supported the spread of INSPIRED to 19 teams in the 10 Canadian provinces contingent upon participation in evaluation. The collaborative evaluation followed a mixed-methods summative approach relying on collated quantitative data, team documents, and surveys sent to core members of the 19 teams...
February 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28569116/patient-and-health-care-professional-perspectives-on-using-telehealth-to-deliver-pulmonary-rehabilitation
#19
J A Inskip, H Novak Lauscher, L C Li, G A Dumont, A Garde, K Ho, A M Hoens, J D Road, C J Ryerson, P G Camp
The objective of this study was to identify the necessary features of pulmonary telerehabilitation (P-TR) from the perspectives of individuals living with chronic lung disease and health care professionals (HCPs) who deliver pulmonary rehabilitation (PR). Focus groups were carried out with patients ( n = 26) and HCPs ( n = 26) to elicit and explore their opinions about the critical elements of in-person PR and ideas for how these elements could be supported using technology. A questionnaire was used to assess technology use, PR experience, and general health status...
February 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28569072/the-role-of-oral-methotrexate-as-a-steroid-sparing-agent-in-refractory-eosinophilic-asthma
#20
David Bilocca, B Hargadon, I D Pavord, R H Green, C E Brightling, P Bradding, A J Wardlaw, N Martin, A C Murphy, S Siddiqui
The use of oral methotrexate for refractory eosinophilic asthma in a tertiary asthma referral centre, Glenfield Hospital, Leicester, was evaluated between January 2006 and December 2014. The patients ( n = 61) were carefully phenotyped at baseline with markers of airway inflammation. In addition, a structured oral methotrexate proforma was utilized to evaluate response to therapy and adverse events. Oral steroid withdrawal was attempted 3 months after commencing treatment. Several outcomes were evaluated at 12 months, including both efficacy and adverse effects; 15% ( n = 9/61) responded by achieving a decrease in daily oral corticosteroid dose (mean 8...
February 2018: Chronic Respiratory Disease
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