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Current Heart Failure Reports

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https://www.readbyqxmd.com/read/28875413/cardiac-palliative-medicine
#1
REVIEW
Todd Barrett
PURPOSE OF REVIEW: Heart failure is an illness with high morbidity and mortality that affects 5.7 million Americans. As advanced heart therapies become more prevalent care for patients and families is becoming more complex. The American Heart Association has released a policy statement recommending continuous, high-quality access to palliative care for all patients with heart failure, and the Center for Medicare Services requires palliative care involvement in mechanical circulatory support teams...
September 6, 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28808861/epidemiology-of-sleep-disordered-breathing-and-heart-failure-what-drives-what
#2
REVIEW
Sushma M Dharia, Lee K Brown
PURPOSE OF REVIEW: The bidirectional relationships that have been demonstrated between heart failure (HF) and central sleep apnea (CSA) demand further exploration with respect to the implications that each condition has for the other. This review discusses the body of literature that has accumulated on these relationships and how CSA and its potential treatment may affect outcomes in patients with CSA. RECENT FINDINGS: Obstructive sleep apnea (OSA) can exacerbate hypertension, type 2 diabetes, obesity, and atherosclerosis, which are known predicates of HF...
August 14, 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28808858/vitamin-d-and-heart-failure
#3
REVIEW
D Marshall Brinkley, Omair M Ali, Sandip K Zalawadiya, Thomas J Wang
PURPOSE: Vitamin D is principally known for its role in calcium homeostasis, but preclinical studies implicate multiple pathways through which vitamin D may affect cardiovascular function and influence risk for heart failure. Many adults with cardiovascular disease have low vitamin D status, making it a potential therapeutic target. We review the rationale and potential role of vitamin D supplementation in the prevention and treatment of chronic heart failure. RECENT FINDINGS: Substantial observational evidence has associated low vitamin D status with the risk of heart failure, ventricular remodeling, and clinical outcomes in heart failure, including mortality...
August 14, 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28803400/novel-biomarkers-for-the-risk-stratification-of-heart-failure-with-preserved-ejection-fraction
#4
REVIEW
Jeremy Cypen, Tariq Ahmad, Jeffrey M Testani, Adam D DeVore
PURPOSE OF REVIEW: The use of biomarkers in heart failure (HF) is a rapidly changing field. The purpose of this review is to assess the current evidence of the use of biomarkers for risk stratification in patients with HF with preserved ejection fraction (HFpEF). RECENT FINDINGS: Despite differences in pathophysiology between HF with reduced ejection fraction and HFpEF, traditional HF biomarkers such as brain natriuretic peptide and troponin retain prognostic value in most HFpEF-specific populations...
August 12, 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28803369/volume-balance-and-intradialytic-ultrafiltration-rate-in-the-hemodialysis-patient
#5
REVIEW
Jason A Chou, Kamyar Kalantar-Zadeh
PURPOSE OF REVIEW: Volume management in hemodialysis patients is often challenging. Assessing volume status and deciding how much fluid to remove during hemodialysis, the so-called ultrafiltration rate (UFR), has remained a conundrum. RECENT FINDINGS: To date there is no objective assessment tool to determine the needed UFR during each hemodialysis session. Higher volume overload or higher UFR is associated with poor outcomes including worse mortality and unfavorable clinical outcomes...
August 12, 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28803272/inpatient-monitoring-of-decompensated-heart-failure-what-is-needed
#6
REVIEW
Danish Ali, Prithwish Banerjee
PURPOSE OF REVIEW: Acute decompensated heart failure is a serious and common condition where close monitoring of symptoms, vital signs, haemodynamic and other markers are needed after the patient is admitted to hospital as the in-hospital outcome is poor. This review focuses on advances in the assessment and monitoring of these patients. RECENT FINDINGS: The adoption of the CHAMP acronym to identify precipitating factors and of the classification using wet-warm, wet-cold, dry-warm and dry-cold categories is an improvement regarding assessment...
August 12, 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28785969/acute-heart-failure-definition-classification-and-epidemiology
#7
REVIEW
Sameer Kurmani, Iain Squire
PURPOSE OF REVIEW: The purpose of this review is to describe the extent and scope of acute heart failure (AHF), place it within its clinical context and highlight some of the difficulties in defining it as a pathophysiological entity. RECENT FINDINGS: A diagnosis of AHF is made when patients present acutely with signs and symptoms of heart failure, often with decompensation of pre-existing cardiomyopathy. The most current guidelines classify based on clinical features at initial presentation and are used to both risk stratify and guide the management of haemodynamic compromise...
August 7, 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28779281/diagnosis-and-management-of-heart-failure-in-long-term-dialysis-patients
#8
REVIEW
Ashraf S Abdo
PURPOSE OF REVIEW: Development of congestive heart failure as a manifestation of various cardiovascular ailments is not only an adverse prognostic factor for patients on long-term dialysis but its presence at the initiation of hemodialysis is another independent indicator of higher mortality. RECENT FINDINGS: The literature reviewed included the most recent studies that assessed the prevalence, incidence, and risk factors associated with dialysis in the setting of congestive heart failure...
August 4, 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28779280/updates-in-cardiac-resynchronization-therapy-for-chronic-heart-failure-review-of-multisite-pacing
#9
REVIEW
Antonios P Antoniadis, Ben Sieniewicz, Justin Gould, Bradley Porter, Jessica Webb, Simon Claridge, Jonathan M Behar, Christopher Aldo Rinaldi
PURPOSE OF REVIEW: Cardiac resynchronization therapy (CRT) reduces the morbidity and mortality of patients with left ventricular (LV) systolic dysfunction and intra-ventricular conduction delay. However, its clinical outcomes are heterogeneous and not all patients show a beneficial response. Multisite pacing (MSP), by stimulating the myocardium from more than one locations, is a potential therapeutic option in patients requiring CRT. This article provides a current update in the methods and outcomes of MSP, as well as in challenges in this field and opportunities for further research and development...
August 4, 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28779279/prevention-of-chemotherapy-induced-cardiomyopathy
#10
REVIEW
David L Payne, Anju Nohria
PURPOSE OF REVIEW: Cardiomyopathy is a significant complication of various cancer treatments and has been best studied in patients receiving anthracyclines and trastuzumab. This paper evaluates strategies to prevent chemotherapy-induced cardiotoxicity. RECENT FINDINGS: Increasing cumulative anthracycline dose, use of ≥2 cardiotoxic therapies, extremes of age, and pre-existing cardiovascular risk factors, or established cardiovascular disease, heighten the risk of developing chemotherapy-induced cardiomyopathy...
August 4, 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28762172/mechanical-circulatory-support-for-decompensated-heart-failure
#11
REVIEW
Tarique Al Musa, Colin Dominic Chue, Hoong Sern Lim
PURPOSE OF REVIEW: Cardiogenic shock from decompensated heart failure is associated with significant morbidity and mortality. Mechanical circulatory support (MCS) improves haemodynamics and reverses organ dysfunction in critically ill patients with cardiogenic shock. This paper summarises the main modalities of mechanical support and their physiological impact, practical considerations, advantages and disadvantages to facilitate a holistic approach in managing a potentially lethal pathology...
July 31, 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28853057/erratum-to-updates-in-cardiac-resynchronization-therapy-for-chronic-heart-failure-review-of-multisite-pacing
#12
Antonios P Antoniadis, Ben Sieniewicz, Justin Gould, Bradley Porter, Jessica Webb, Simon Claridge, Jonathan M Behar, Christopher Aldo Rinaldi
No abstract text is available yet for this article.
October 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28707261/from-inflammation-to-fibrosis-molecular-and-cellular-mechanisms-of-myocardial-tissue-remodelling-and-perspectives-on-differential-treatment-opportunities
#13
REVIEW
Navin Suthahar, Wouter C Meijers, Herman H W Silljé, Rudolf A de Boer
PURPOSE OF REVIEW: In this review, we highlight the most important cellular and molecular mechanisms that contribute to cardiac inflammation and fibrosis. We also discuss the interplay between inflammation and fibrosis in various precursors of heart failure (HF) and how such mechanisms can contribute to myocardial tissue remodelling and development of HF. RECENT FINDINGS: Recently, many research articles attempt to elucidate different aspects of the interplay between inflammation and fibrosis...
August 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28674911/the-basic-metabolic-profile-in-heart-failure-marker-and-modifier
#14
REVIEW
Ahmed Elfar, Kamalanathan K Sambandam
PURPOSE OF REVIEW: The physiologic determinants of each of the components of the basic metabolic profile in patients with heart failure will be explored. Additionally, the review will discuss the prognostic value of alterations in the basic metabolic profile as well as their effects on management. RECENT FINDINGS: Abnormalities in the basic metabolic profile have significant correlation with clinical outcomes and can modify treatment in heart failure. Hypochloremia has recently received increased attention for these reasons...
August 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28669000/towards-holistic-heart-failure-management-how-to-tackle-the-iron-deficiency-epidemic
#15
REVIEW
Lucas N L Van Aelst, Dominiek Mazure, Alain Cohen-Solal
PURPOSE OF REVIEW: Heart failure (HF) is a common, costly, disabling, and deadly clinical syndrome and often associated with one or several co-morbidities complicating its treatment or worsening its symptoms. During the last decade, iron deficiency (ID) got recognized as a frequent, debilitating yet easily treatable co-morbidity in HF. In this review, we focus on new evidence that emerged during the last 5 years and discuss the epidemiology, the causes, and the clinical consequences of ID in HF...
August 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28667492/inflammation-cause-or-consequence-of-heart-failure-or-both
#16
REVIEW
Sophie Van Linthout, Carsten Tschöpe
PURPOSE OF REVIEW: With the intention to summarize the currently available evidence on the pathophysiological relevance of inflammation in heart failure, this review addresses the question whether inflammation is a cause or consequence of heart failure, or both. RECENT FINDINGS: This review discusses the diversity (sterile, para-inflammation, chronic inflammation) and sources of inflammation and gives an overview of how inflammation (local versus systemic) can trigger heart failure...
August 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28667491/sglt-2-inhibitors-in-heart-failure-implications-for-the-kidneys
#17
REVIEW
Frederik H Verbrugge, Pieter Martens, Wilfried Mullens
PURPOSE OF REVIEW: This review aims to summarize the renal effects of sodium-glucose transporter-2 (SGLT-2) inhibitors and their potential implications in heart failure pathophysiology. RECENT FINDINGS: In patients with diabetes and established atherosclerosis, the SGLT-2 inhibitor empagliflozin versus placebo significantly reduced the rate of heart failure admissions with 35%. Moreover, empagliflozin slowed kidney disease progression and reduced the need for renal replacement therapy...
August 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28667490/biomarkers-in-sleep-apnea-and-heart-failure
#18
REVIEW
Ying Y Zhao, Reena Mehra
PURPOSE OF REVIEW: Sleep-disordered breathing (SDB) is highly prevalent in heart failure (HF) and may confer significant stress to the cardiovascular system and increases the risk for future cardiovascular events. The present review will provide updates on the current understanding of the relationship of SDB and common HF biomarkers and the effect of positive airway pressure therapy on these biomarkers, with particular emphasis in patients with coexisting SDB and HF. RECENT FINDINGS: Prior studies have examined the relationship between HF biomarkers and SDB, and the effect of SDB treatment on these biomarkers, with less data available in the context of coexisting SDB and HF...
August 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28660543/therapeutic-strategies-targeting-inherited-cardiomyopathies
#19
REVIEW
Kenneth Varian, W H Wilson Tang
PURPOSE OF REVIEW: Cardiomyopathies due to genetic mutations are a heterogeneous group of disorders that comprise diseases of contractility, myocardial relaxation, and arrhythmias. Our goal here is to discuss a limited list of genetically inherited cardiomyopathies and the specific therapeutic strategies used to treat them. RECENT FINDINGS: Research into the molecular pathophysiology of the development of these cardiomyopathies is leading to the development of novel treatment approaches...
August 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28656517/treatment-of-hyperkalemia-in-heart-failure
#20
REVIEW
Ersilia M DeFilippis, Akshay S Desai
PURPOSE OF REVIEW: The aim of this paper is to discuss strategies for prevention and management of hyperkalemia in patients with heart failure, including the role of novel therapies. RECENT FINDINGS: Renin-angiotensin-aldosterone system (RAAS) antagonists, including angiotensin-converting enzyme inhibitors (ACEI), angiotensin receptor blockers (ARB), and mineralocorticoid receptor antagonists (MRA) decrease mortality and morbidity in heart failure but increase the risk of hyperkalemia, especially when used in combination...
August 2017: Current Heart Failure Reports
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