Masaki Yoshida, Kyong-Oh Shin, Sora Muraoka, Yerim Choi, Jae-Ho Park, Soo-Hyun Park, Jin-Taek Hwang, Kyungho Park, Yoshikazu Uchida
INTRODUCTION: The outermost layer of the skin, the epidermis, is directly exposed to external stress (e.g., irradiation, allergens and chemicals). Changes in epidermal conditions/environment in response to this stress could also influence conditions of the dermis, located directly beneath the epidermis. Yet, whether/how any epidermal environment changes in response to external stress affect dermal functions has not been completely clarified. METHODS: We employed ultraviolet irradiation B (UVB) (which does not reach the dermis) as a model of external stress...
March 16, 2023: Skin Pharmacology and Physiology