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Therapeutic Apheresis and Dialysis

journal
https://www.readbyqxmd.com/read/29024501/hemodialysis-decreases-the-concentration-of-accumulated-plant-phenols-in-the-plasma-of-patients-on-maintenance-dialysis-influence-of-residual-renal-function
#1
Piotr Jan Nowak, Radoslaw Wilk, Anna Prymont-Przyminska, Anna Zwolinska, Agata Sarniak, Anna Wlodarczyk, Jeffrey de Graft-Johnson, Beata Mamelka, Anna Zasowska-Nowak, Piotr Bartnicki, Dariusz Nowak, Michal Nowicki
Plant phenols may accumulate in end-stage kidney disease. The effect of hemodialysis on their plasma concentration remains poorly determined. Contingent on concentration, health-promoting or noxious effects occur; therefore, we assessed plasma concentration in hemodialyzed patients. In total, 21 maintenance hemodialyzed patients with diuresis < 500 mL per day (with oliguria), nine hemodialyzed patients with diuresis ≥ 500 mL per day (without oliguria) and 31 healthy volunteers were included. Nine phenolic acids were identified with high-performance liquid chromatography and total polyphenol concentration was determined with the Folin-Ciocalteu method in pre- or post-hemodialysis plasma and pre- or intra-hemodialysis dialysate...
October 11, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29024403/polymicrobial-bacteremia-involving-comamonas-testosteroni-in-a-patient-on-dialysis-with-acute-appendicitis
#2
LETTER
Yao-Min Hung, Yun-Te Chang, Chih-Hsiang Kao
No abstract text is available yet for this article.
October 10, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28980761/parathyroid-nodular-hyperplasia-and-responsiveness-to-drug-therapy-in-renal-secondary-hyperparathyroidism-an-open-question
#3
REVIEW
Carlo Vulpio, Maurizio Bossola
The goal of the pharmacological therapy in secondary hyperparathyroidism (SHPT) is to reduce serum levels of parathyroid hormone and phosphorus, to correct those of calcium and vitamin D, to arrest or reverse the parathyroid hyperplasia. However, when nodular hyperplasia or an autonomous adenoma develops, surgery may be indicated. We reviewed the literature with the aim of defining if the echographic criteria predictive of unresponsiveness of SHPT to calcitriol therapy are valid also in the cinacalcet era and if drug therapy may reverse nodular hyperplasia of parathyroid gland (PTG)...
October 5, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28976071/prevalence-of-and-predictive-factor-for-abdominal-aortic-calcification-in-thai-chronic-kidney-disease-patients
#4
Dusit Lumlertgul, Surasak Kantachuvesiri, Somboon Apichaiyingyurd, Worapot Treamtrakanpon, Manoch Rattanasompattikul, Pongsathorn Gojaseni, Prasert Thanakitcharu, Thananda Trakarnvanich, Ussanee Poonvivatchaikarn, Kriengsak Vareesangthip
Presence and severity of cardiovascular calcifications strongly predict cardiovascular morbidity and mortality in patients with CKD. This multicenter, cross-sectional study primarily aimed to determine prevalence of abdominal aortic calcification (AAC) detected by plain lateral abdominal radiograph, and secondarily aimed to assess predictive factors for AAC. Patients (N = 1500), aged 18-70 years, with CKD stages 3-5D for ≥3 months prior to evaluation, were enrolled at 24 study centers in Thailand; 54...
October 4, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28971600/fgf23-level-and-intima-media-thickness-are-elevated-from-early-stages-of-chronic-kidney-disease
#5
Andreja Figurek, Goce Spasovski, Snjezana Popovic-Pejicic
Considering high cardiovascular (CV) risk in chronic kidney disease (CKD), the aim of this cross-sectional study was to assess the association between carotid intima-media thickness (IMT) and fibroblast growth factor (FGF) 23 as important players in CV pathophysiology. Eighty-seven patients with mean estimated glomerular filtration rate 40.1 mL/min per 1.73 m(2) were involved. FGF23 and IMT were elevated from early stages of CKD. Mean IMT value was 1.10 ± 0.20 mm, being significantly elevated starting from early CKD, showing no correlation with FGF23 (r = -0...
October 3, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28971592/residual-renal-function-in-hemodialysis-and-inflammation
#6
Patricia de Sequera, Elena Corchete, Lourdes Bohorquez, Marta Albalate, Rafael Perez-Garcia, Matilde Alique, María Marques, Estefanya García-Menéndez, José Portolés, Rafael Ramirez
Residual renal function (RRF) has an important effect on uremic toxin clearance, on volume control, on quality of life, and on mortality. In patients with chronic kidney disease (CKD), microinflammation with an increased percentage of CD14(+) /CD16(++) inflammatory monocytes has been reported, even with no clinical evidence of inflammation. No correlation has been established between these and RRF in hemodialysis (HD) patients. Our objective was to assess the relationship between RRF and the inflammatory parameters in HD patients...
October 3, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28971590/addition-of-novel-biomarkers-for-predicting-all-cause-and-cardiovascular-mortality-in-prevalent-hemodialysis-patients
#7
Kazuomi Yamashita, Sonoo Mizuiri, Yoshiko Nishizawa, Kenichiro Shigemoto, Shigehiro Doi, Takao Masaki
Novel biomarkers might improve the prediction of mortality in hemodialysis (HD) patients. We simultaneously measured the levels of conventional and novel biomarkers [serum N-terminal pro-brain natriuretic peptide (NT-proBNP), intact fibroblast growth factor-23 (FGF23), β2-microglobulin (β2MG), cystatin C, and high-sensitivity C-reactive protein (hsCRP)] in 307 prevalent Japanese HD patients. There were 66 all-cause deaths, and 25 cardiovascular (CV) deaths during 2 years, which were assessed using Cox models and concordance (C)-statistics...
October 3, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28961387/red-blood-cell-distribution-width-is-associated-with-all-cause-and-cardiovascular-mortality-in-hemodialysis-patients
#8
Hirotaka Fukasawa, Kento Ishibuchi, Mai Kaneko, Hiroki Niwa, Hideo Yasuda, Hiromichi Kumagai, Ryuichi Furuya
Red blood cell distribution width (RDW) is an index of red blood cell variability that is usually used to differentiate the cause of anemia. However, clinical evidence for the relationship between RDW and mortality in hemodialysis patients is still lacking. We performed a single center, prospective longitudinal study. During more than 5 years of follow-up in 80 patients undergoing maintenance hemodialysis, 34 patients (42.5%) died. In the Kaplan-Meier curve analyses, higher RDW levels (≥ 14.9%) were significantly associated with all-cause and cardiovascular mortality (log-rank test, P < 0...
September 29, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28960860/impact-of-statins-on-arteriovenous-fistulas-outcomes-a-meta-analysis
#9
Qingsong Wan, Li Li, Shikun Yang, Fenfen Chu
Statins are effective lipid-lowering drugs with beneficial pleiotropic effects for vascular remodeling processes, statins may have a beneficial effect on the function of arteriovenous fistulas (AVFs) in hemodialysis (HD) patients. Therefore, we performed this systematic review to assess the protective effects of statin therapy in HD patients. The randomized controlled trials (RCTs) or quasi-RCTs and retrospective cohort studies (RCS) of statin therapy for the function of AVFs in HD patients were searched from multiple databases...
September 28, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28960840/selection-of-dna-aptamer-that-blocks-the-fibrillogenesis-of-a-proteolytic-amyloidogenic-fragment-of-%C3%AE-2-m
#10
Kanon Fukasawa, Yuichiro Higashimoto, Yukio Ando, Yoshihiro Motomiya
Dialysis-related amyloidosis (DRA) is a severe complication of hemodialysis that results in progressive destruction of bones and joints. Elevated concentrations of the β2 -microglobulin (β2 m) level in the serum of subjects on hemodialysis promote the formation of amyloid fibrils in osteoarticular tissues. β2 m lacking the N-terminal six residues of the mature protein (ΔN6β2 m) constitutes 25-30% of β2 m in ex vivo DRA amyloid. Unlike full-length wild-type β2 m, ΔN6β2 m forms amyloid fibrils at neutral pH in vitro...
September 28, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28960755/adsorption-of-nafamostat-mesilate-on-an69st-membranes-a-single-center-retrospective-and-in-vitro-study
#11
Yoshihiko Nakamura, Shuuji Hara, Hiroki Hatomoto, Shintaro Yamasaki, Takafumi Nakano, Motoyasu Miyazaki, Norihiko Matsumoto, Yuhei Irie, Hiroyasu Ishikura
We examined whether AN69ST (acrylonitrile and methallyl sulfonate copolymer) membranes adsorb nafamostat mesilate. This study retrospectively analyzed 87 continuous hemodiafiltration sessions in vivo. We divided the continuous hemodiafiltration sessions into AN69ST and non-AN69ST groups using the nafamostat mesilate dose and activated clotting time as indicators of nafamostat mesilate adsorption onto the membrane. Furthermore, we studied the in vitro adsorption of nafamostat mesilate from nafamostat mesilate solutions onto four different hemodialysis membranes...
September 28, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28941055/inhibition-of-inflammatory-cytokines-and-induction-of-myeloid-derived-suppressor-cells-by-the-effects-of-granulocyte-and-monocyte-adsorption-apheresis
#12
Masanao Sakanoue, Yuko Higashi, Takuro Kanekura
Pro-inflammatory cytokines are involved in the pathogenesis of inflammatory skin diseases attributable to activated neutrophils and macrophages. Myeloid-derived suppressor cells (MDSCs) play an important role in the regulation of the immune response and possess strong immunosuppressive and anti-inflammatory properties. Granulocyte and monocyte adsorption apheresis (GMA), an extracorporeal apheresis instrument featuring columns containing cellulose acetate (CA) beads, is designed to remove pathogenic myeloid lineage cells...
September 22, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28941049/body-composition-and-inflammation-in-hemodialysis-patients
#13
Ante Mandic, Ivan Cavar, Ivana Skoro, Ivan Tomic, Kristina Ljubic, Slavica Coric, Ivanka Mikulic, Igor Azinovic, Danijel Pravdic
The volume state of dialysis patients is important in guiding the dialysis process. Volume overload in these patients is associated with inflammation. The objectives of the present study were to assess the body composition of patients on hemodialysis; to determine the concentrations of B-type natriuretic peptide (BNP) in plasma and evaluate the association of BNP concentrations with volume overload; to determine the concentrations of C-reactive protein (CRP), albumin and superoxide dismutase (SOD) activities as indicators of inflammatory or antioxidant processes...
September 22, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28913961/generalized-pustular-psoriasis-with-il-36-receptor-antagonist-mutation-successfully-treated-with-granulocyte-and-monocyte-adsorption-apheresis-accompanied-by-reduced-serum-il-6-level
#14
LETTER
Asami Fujii, Hidenori Ohnishi, Mariko Seishima
No abstract text is available yet for this article.
September 15, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28905484/occult-hepatitis-b-virus-infection-with-increased-virus-dna-levels-in-a-chronic-hemodialysis-patient
#15
LETTER
Yoshitaka Koshino, Yasuyuki Shinozaki, Takashi Wada
No abstract text is available yet for this article.
September 14, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28868755/matrix-metalloproteinase-2-predicts-arteriovenous-fistula-failure-in-hemodialysis-patients
#16
Dacian Călin Tirinescu, Ciprian Tomuleasa, Laura Pop, Cosmina Ioana Bondor, Dan Ştefan Vlăduţiu, Ioan Mihai Paţiu, Crina Claudia Rusu, Diana Tania Moldovan, Alina Potra, Ina Maria Kacsó
In hemodialysis patients the principal cause of arteriovenous fistula dysfunction is stenosis. Matrix-metalloproteinase-2 is implicated in the pathophysiological mechanism of stenosis development. Our study tried to assess the clinical impact of this protease on arteriovenous fistula survival. Seventy-nine prevalent dialysis patients with functional arteriovenous fistulas were included in the study. The presence of stenosis and the serum levels of matrix-metalloproteinase-2 were determined at the beginning of the study...
September 3, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28805307/early-graft-loss-in-two-recipients-of-mate-kidneys-from-the-same-donor-with-diabetic-nephropathy
#17
LETTER
Daigo Okada, Masayoshi Okumi, Kazunari Tanabe
No abstract text is available yet for this article.
August 14, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29024468/upcoming-meetings-therapeutic-apheresis-and-dialysis-october-2017
#18
(no author information available yet)
No abstract text is available yet for this article.
October 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29024466/the-isfa-wishes-to-acknowledge-the-following-2017-corporate-sponsors
#19
(no author information available yet)
No abstract text is available yet for this article.
October 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28895297/changing-trends-in-therapeutic-plasmapheresis-an-indian-perspective
#20
Aseem K Tiwari, Gunjan Bhardwaj, Geet Aggarwal, Dinesh Arora, Ravi C Dara, Devi P Acharya, Sangeetha Gayam, Jui Choudhuri
Indications for therapeutic apheresis (TA) are dynamic; they keep changing and expanding because of introduction of newer treatment modalities and accumulating evidence in the form of case-reports, case-series and original articles. We evaluated our therapeutic plasmapheresis (TP) data and compared this data with an earlier published Indian report for indications, frequency, response rate and adverse reactions. We conducted a retrospective analysis of all TP procedures performed from January 2014 to June 2016 in department of Transfusion Medicine at a tertiary care hospital...
October 2017: Therapeutic Apheresis and Dialysis
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