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Therapeutic Apheresis and Dialysis

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https://www.readbyqxmd.com/read/28805348/levocarnitine-decreases-intradialytic-hypotension-episodes-a-randomized-controlled-trial
#1
Héctor Raúl Ibarra-Sifuentes, Ángel Del Cueto-Aguilera, Daniel Alberto Gallegos-Arguijo, Sergio Andres Castillo-Torres, Raymundo Vera-Pineda, Rolando Jacob Martínez-Granados, Alexandro Atilano-Díaz, Jesus Eduardo Cuellar-Monterrubio, Cesar Octaviano Pezina-Cantú, Edgar de Jesús Martínez-Guevara, Juan Francisco Ortiz-Treviño, Guillermo Rubén Delgado-García, José Guadalupe Martínez-Jiménez, Jesús Cruz-Valdez, Concepción Sánchez-Martínez
Intradialytic hypotension is common complication in stage 5 chronic kidney disease patients on hemodialysis. Incidence ranges from 15 to 30%. These patients have levocarnitine deficiency. A randomized, placebo-controlled quadruple-blinded trial was designed to demonstrate the levocarnitine efficiency on intradialytic hypotension prevention. Patients were randomized into four groups, to receive levocarnitine or placebo. During the intervention period, levocarnitine and placebo was administered 0 and 30 min before each hemodialysis session, respectively...
August 14, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28805307/early-graft-loss-in-two-recipients-of-mate-kidneys-from-the-same-donor-with-diabetic-nephropathy
#2
LETTER
Daigo Okada, Masayoshi Okumi, Kazunari Tanabe
No abstract text is available yet for this article.
August 14, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28795535/update-on-postdialysis-rebound-by-a-new-technology-in-hemodialysis
#3
Alicia García Testal, David Hervás Marín, Rafael García Maset, Pilar Royo Maicas, Inmaculada Soledad Rico Salvador, Pau Olagüe Díaz, Jose Enrique Fernández Najera, Eduardo Torregrosa De Juan, Caterina Benedito Carrera
After dialysis ends, urea continued movement causes rebound postdialysis, with values at about 20%. New techniques have been incorporated into hemodialysis, but their relationship with rebound has not yet been studied. This study aimed to quantify urea rebound at 30-min postdialysis during sessions using polysulfone filters and high-flow versus online hemodiafiltration, and to define its correlation with body composition measured by bioimpedance by a cross-sectional study with 69 patients (December 2015 to January 2016)...
August 9, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28741804/does-whey-protein-supplementation-improve-the-nutritional-status-in-hypoalbuminemic-peritoneal-dialysis-patients
#4
Kamal Hassan
Limited data are available regarding the effects of whey protein on the nutritional status of the peritoneal dialysis population. This study evaluated the effects of whey protein supplementation for 12 weeks on the nutritional status in hypoalbuminemic peritoneal dialysis patients. Thirty-six stable adult patients on maintenance peritoneal dialysis with serum albumin levels <3.5 g/dL were enrolled in the study and were divided into two groups similar in their serum albumin and normalized protein equivalent of total nitrogen appearance (nPNA)...
July 25, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28731276/attempt-to-harvest-a-sufficient-number-of-mononuclear-cells-in-an-appropriate-blood-product-volume-by-modification-of-the-default-apheresis-setting
#5
Yumi Tanaka, Kohshi Ohishi, Toshiki Sawai, Hitoshi Iwasaki, Shinichi Kageyama, Masahiro Masuya, Takeshi Matsumoto, Takashi Tanigawa, Hideo Wada, Hiroshi Shiku, Masaaki Ito, Naoyuki Katayama
To harvest for T cell therapy, a 1.6-fold higher number of CD3(+) T cells was collected with MNC mode (N = 10) compared with Auto PBSC mode (N = 5) in COBE Spectra cell separator, but the blood product volume was increased by 3.5-fold. For therapeutic angiogenesis therapy, apheresis was initially performed using Auto PBSC mode (N = 4) to fine tune the blood product volume to omit cell concentration, but the collected number of mononuclear cells was lower than expected. However, an increase of the harvest cycle number from 3...
July 21, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28714271/influence-of-residual-renal-function-in-carotid-modeling-as-a-marker-of-early-atherosclerosis-in-dialysis-patients
#6
Merita Rroji, Nereida Spahia, Saimir Seferi, Myftar Barbullushi, Goce Spasovski
Atherosclerosis is frequently present in patients with chronic kidney disease (CKD) treated with dialysis. We evaluated the association between residual renal function (RRF), phosphate level, inflammation and other risk factors in carotid modeling as a marker of early atherosclerosis in peritoneal dialysis (PD) compared with hemodialysis (HD) patients. We studied 39 stable PD and 53 HD patients on renal replacement therapy (RRT) for 3 to 36 months duration. B-mode ultrasonography was used to determine carotid artery intima media thickness (CIMT)...
July 17, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28714255/hypoglycemic-emergency-in-patients-with-diabetic-kidney-disease
#7
LETTER
Kiyonori Ito, Susumu Ookawara, Yoshiyuki Morishita
No abstract text is available yet for this article.
July 17, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28714149/elimination-of-plasma-cytokines-markedly-improves-non-septic-multiple-organ-dysfunction-syndrome-in-human-immunodeficiency-virus-associated-hodgkin-lymphoma
#8
LETTER
Maki Fujiwara, Soshi Yanagida, Hiroko Kakita, Nobuyoshi Arima
No abstract text is available yet for this article.
July 17, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28714124/primary-central-nervous-system-post-transplant-lymphoproliferative-disorder-following-kidney-transplantation-a-multi-institution-study-in-japan-over-30%C3%A2-years
#9
Hiroki Ishihara, Masayoshi Okumi, Kazunari Tanabe
No abstract text is available yet for this article.
July 17, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28691214/earthquake-preparedness-among-japanese-hemodialysis-patients-in-prefectures-heavily-damaged-by-the-2011-great-east-japan-earthquake
#10
Hidehiro Sugisawa, Yumiko Shimizu, Tamaki Kumagai, Hiroaki Sugisaki, Seiji Ohira, Toshio Shinoda
The purpose of this study was to explore the factors related to earthquake preparedness in Japanese hemodialysis patients. We focused on three aspects of the related factors: health condition factors, social factors, and the experience of disasters. A mail survey of all the members of the Japan Association of Kidney Disease Patients in three Japanese prefectures (N = 4085) was conducted in March, 2013. We obtained 1841 valid responses for analysis. The health factors covered were: activities of daily living (ADL), mental distress, primary renal diseases, and the duration of dialysis...
July 10, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28665535/pre-dialysis-neutrophil-lymphocyte-ratio-a-novel-and-strong-short-term-predictor-of-all-cause-mortality-in-patients-with-diabetic-nephropathy-results-from-a-single-center-study
#11
Hiroyuki Sato, Yoichi Takeuchi, Ken Matsuda, Saeko Kagaya, Ayako Saito, Hirotaka Fukami, Yoshie Ojima, Tasuku Nagasawa
Neutrophil-lymphocyte ratio (NLR) is an inflammatory marker affecting the prognosis of end-stage renal disease (ESRD) patients. This study aimed to evaluate NLR levels predicting all-cause mortality in ESRD patients with diabetic nephropathy (DN), which have not been evaluated. We recruited 151 isolated DN patients who started hemodialysis between January 2009 and December 2014 at the Japanese Red Cross Ishinomaki Hospital. The primary outcomes were 1- and 3-year survival rates. The association between NLR and survival rate was evaluated using the Kaplan-Meier method and Cox proportional hazard regression analysis...
June 30, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28597511/successful-treatment-of-enterohemorrhagic-escherichia-coli-induced-acute-encephalopathy-and-hemolytic-uremic-syndrome-with-polymyxin-b-direct-hemoperfusion
#12
Hisashi Kaneda, Masaki Shimizu, Akihiro Yachie
No abstract text is available yet for this article.
June 8, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28594111/bone-histomorphometry-in-an-osteoporotic-hemodialysis-patient-treated-with-denosumab
#13
Yajima Ibuki, Toyosi Hukuda, Sakuyosi Tabata, Akemi Ito
No abstract text is available yet for this article.
June 8, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28593648/evaluation-of-first-line-sorafenib-treatment-for-metastatic-renal-cell-carcinoma-in-kidney-transplant-patients-a-single-center-experience-with-four-cases
#14
LETTER
Hiroki Ishihara, Tsunenori Kondo, Kazunari Tanabe
No abstract text is available yet for this article.
June 8, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28661098/efficacy-of-cryofiltration-for-treatment-of-mixed-cryoglobulinemia-a-report-of-four-cases
#15
Yoshihiro Taniyama, Yoshihisa Nakatani, Toshiaki Matsuoka, Miyo Takahashi, Kazuyuki Shimizu, Sachiyo Yamamoto, Yuki Inoue, Sayoko Ohnishi, Norihiro Kobayashi, Yukihito Nakano, Masahiro Takami, Shuji Arima
Cryoglobulinemia can induce systemic vasculitis affecting various organs such as skin, peripheral nerves, and kidney. The disease can induce chronic organ failure and even be life-threatening. Cryofiltration has been applied for the treatment of cryoglobulinemic vasculitis. We have experienced four cases with mixed cryoglobulinemia showing severe and progressive clinical manifestations, including skin purpura, nephrotic syndrome, acute kidney injury, and peripheral neuropathy. Cryofiltration in conjunction with conventional pharmacological therapies appeared to be safe and effective...
June 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28661097/evaluating-the-efficacy-of-double-filtration-plasmapheresis-in-treating-five-patients-with-drug-resistant-pemphigus
#16
Takaaki Higashihara, Masaaki Kawase, Maasa Kobayashi, Mizuki Hara, Hiroyuki Matsuzaki, Rie Uni, Mimiko Matsumura, Takafumi Etoh, Hideki Takano
Double-filtration plasmapheresis is an effective and safe treatment for pemphigus. We retrospectively evaluated the decrease in autoantibody titer and pemphigus disease area index following double-filtration plasmapheresis in five patients with moderate to severe pemphigus, who were physically and/or serologically unresponsive to 1.0 mg/kg per day of prednisolone and other supportive drugs and ointments. The percentage reduction in autoantibodies 85.6 ± 14.4% (P = 0.00014), and that in pemphigus disease area index was 75...
June 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28661096/fibrinogen-reduction-during-selective-plasma-exchange-due-to-membrane-fouling
#17
Atsushi Ohkubo, Tomokazu Okado, Satoko Miyamoto, Yurie Hashimoto, Shigeto Komori, Motoki Yamamoto, Takuma Maeda, Ayako Itagaki, Hiroko Yamamoto, Hiroshi Seshima, Naoki Kurashima, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Shinichi Uchida, Tatemitsu Rai
Fibrinogen is substantially reduced by most plasmapheresis modalities but retained in selective plasma exchange using Evacure EC-4A10 (EC-4A). Although EC-4A's fibrinogen sieving coefficient is 0, a session of selective plasma exchange reduced fibrinogen by approximately 19%. Here, we investigated sieving coefficient in five patients. When the mean processed plasma volume was 1.15 × plasma volume, the mean reduction of fibrinogen during selective plasma exchange was approximately 15%. Fibrinogen sieving coefficient was 0 when the processed plasma volume was 1...
June 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28661095/protein-concentration-of-refractory-ascites-in-cancer-patients-is-reflected-by-the-presence-and-severity-of-peritoneal-and-liver-metastasis
#18
Yosuke Yamada, Akinori Yamaguchi, Makoto Harada, Yukifumi Kurasawa, Yuuta Hara, Daiki Yamazaki, Satoshi Fujita, Kosuke Sonoda, Tomoe Masuda, Aiko Yamada, Yohei Ogawa, Koji Hashimoto, Yuji Kamijo
Ascites total protein concentration (A-TP) affects the performance of cell-free and concentrated ascites reinfusion therapy (CART). As the factors determining A-TP remain unclear, we examined peritoneal and liver metastasis. Among 98 patients who received CART, 68 with cancer, ascites from no other apparent cause, and complete CT and A-TP data were recruited. Sixty-six patients (97%) with peritoneal and/or liver metastasis on CT were divided into the peritoneal metastasis group (PM group), peritoneal and liver metastasis group (PM + LM group), and liver metastasis group (LM group)...
June 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28661094/effect-of-temperature-on-granulocyte-and-monocyte-adsorption-to-cellulose-acetate-beads
#19
Shoichi Nishise, Yuji Takeda, Yasuhiko Abe, Yu Sasaki, Hidetoshi Nara, Hironobu Asao, Yoshiyuki Ueno
Granulocyte and monocyte (GM) adsorptive apheresis (GMA) is an effective therapy for inflammatory disorders including inflammatory bowel disease (IBD). During GMA, the blood of a patient with IBD passes through a column to contact cellulose acetate (CA) beads at a temperature below body temperature, likely close to room temperature. Here we investigated the effect of temperature on GM adsorption to CA beads in vitro. We incubated peripheral blood with and without CA beads at 5°C, 25°C, 37°C, and 43°C and calculated the ratios of adsorbed GMs...
June 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28661093/severe-glyphosate-surfactant-intoxication-successfully-treated-with-continuous-hemodiafiltration-and-direct-hemoperfusion-case-report
#20
LETTER
Taro Ozaki, Tadashi Sofue, Yasuhiro Kuroda
No abstract text is available yet for this article.
June 2017: Therapeutic Apheresis and Dialysis
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