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Chinese Journal of Integrative Medicine

Xiao-Fei Wu, Ya-Juan Yu, Ling-Mei Ying, Wei-Fen Tan, Xiao-Yan Zhan, Ling-Cong Wang
OBJECTIVE: To explore the preventive effect of applying hot compress with Chinese herbal salt packets (CHSP) to puncture vessels under aseptic conditions during peripherally inserted central catheter (PICC) on postoperative phlebitis. METHODS: A total of 720 hospitalized patients undergoing first PICC were assigned to treatment and control groups (360 cases each group) according to a random number table. The control group received conventional catheterization and nursing care...
June 27, 2018: Chinese Journal of Integrative Medicine
Xing-Jiang Xiong, Peng-Qian Wang, Sheng-Jie Li
OBJECTIVE: To evaluate the efficacy and safety of blood-letting therapy (BLT) in treatment of hypertension. METHODS: A comprehensive electronic and manual bibliographic searches were performed in Cochrane Central Register of Controlled Trials, Excerpt Medica Database (EMBASE), PubMed, China National Knowledge Infrastructure, Chinese Scientific Journal Database, Chinese Biomedical Literature Database, and Wanfang Database to identify randomized controlled trials (RCTs) in which hypertensive patients were treated with BLT or BLT plus antihypertensive drugs (BPAD) against placebo, no treatment or antihypertensive drugs...
June 25, 2018: Chinese Journal of Integrative Medicine
Wei Chen, En-Chang Li, Wei-Rong Zheng
From the event of TU You-you winning the Nobel Prize, this paper briefly reviewed the history of formation and development of policies on Chinese medicine (CM) in China. On the basis of analyzing the causes of policies on CM, it is believed that policies on CM in China may have 4 kinds of enlightenments to the development of complementary and alternative medicine (CAM) in the world. Forming the political advantages of policy-making by main leaders of the country attaching importance to CAM; implementing a diversified health care system policy for the goal of maximizing people's health interests; ensuring development of CAM by the coerciveness of law and the timeliness of policy adjustment; and promoting the protection and mining, sorting out and improving of CAM based on open and comprehensive policies...
June 25, 2018: Chinese Journal of Integrative Medicine
Guang Zheng, He Zhang, Yun Yang, Ying-Li Sun, Yan-Jing Zhang, Ju-Ping Chen, Ting Hao, Cheng Lu, Hong-Tao Guo, Ge Zhang, Dan-Ping Fan, Xiao-Juan He, Ai-Ping Lu
OBJECTIVE: To explore the molecular-level mechanism on the hematopoiesis effect of Angelicae Sinensis Radix (ASR) with systems-based interactome analysis. METHODS: This systems-based interactome analysis was designed to enforce the workflow of "ASR (herb)→compound→target protein→internal protein actions→ending regulated protein for hematopoiesis". This workflow was deployed with restrictions on regulated proteins expresses in bone marrow and anemia disease and futher validated with experiments...
June 25, 2018: Chinese Journal of Integrative Medicine
Jing-Si Wang, Qiu-Yun Zhang, Jin-Lian Cheng, Lan-Yu Chen, Nai-Li Yao, Gui-Zhi Sun, Yu-Ling Chu
Hepatic fibrosis is a common feature of almost all chronic liver diseases. Formation of new vessels (angiogenesis) is a process strictly related to the progressive fibrogenesis which leads to cirrhosis and liver cancer. This review mainly concerns the relationship between angiogenesis and hepatic fibrosis, by considering the mechanism of angiogenesis, cells in angiogenesis, anti-angiogenic and Chinese medicine therapies.
June 25, 2018: Chinese Journal of Integrative Medicine
Fu-Rong Zhu, Yong-Ning Li, Shu-Lan He, Qian-Shun Chen, Xun-Yu Xu
OBJECTIVE: To investigate the anti-proliferative effects of saponins prepared from Plena Clematis (PC) cultured in Fujian Province, China on 4 human tumor cell lines and its possible anti-tumor mechanism. METHODS: The growth inhibition assays of saponins on human esophageal squamous carcinoma cell line (EC9706), human hepatoma cell line (HepG-2), human oral cancer cell line (KB) and human gastric cancer cell line (BGC-823) were evaluated in vitro by thiazolyl blue (MTT) method...
June 21, 2018: Chinese Journal of Integrative Medicine
Hai-Ping Zhao, Ping Liu, Chang-Min Xu, Guang-Wen Li, Li Gao, Yu-Min Luo
OBJECTIVE: To identify the differentially expressed microRNAs (miRNAs) profiles of yang and yin syndromes in patients with acute ischemic stroke, and to provide the molecular basis of the classififi cation of these two syndrome types in acute ischemic stroke patients. METHODS: A microarray assay was performed to assess the expression pattern of miRNAs in the lymphocyte of acute ischemic stroke patients. Target genes for the deregulated miRNAs were predicated using the online bioinformatic algorithms and functional annotation via Kyoto encyclopedia of genes and genomes pathway analysis for miRNAs predicted targets was carried out...
June 20, 2018: Chinese Journal of Integrative Medicine
Jian Huo, Li-Sha Liu, Wen-Yuan Jian, Jie-Ping Zeng, Jun-Guo Duan, Xue-Jing Lu, Shuo Yin
BACKGROUND: Microvascular complications in type 2 diabetes (T2DM), including diabatic retinopathy (DR), diabetic kidney disease (DKD), diabetic peripheral neuropathy (DPN) are the leading causes of visual loss, end-stage renal disease or amputation, while the current therapies are still unsatisfactory. Chinese medicine (CM) has been widely used for treating diabetic mellitus. However, most of the previous studies focused on the single complication. The role of CM treatment in T2DM patients with 2 or multiple microvascular complications is not clear...
June 18, 2018: Chinese Journal of Integrative Medicine
Zhao-You Tang
No abstract text is available yet for this article.
June 18, 2018: Chinese Journal of Integrative Medicine
Jun Zhao, Xing Liao, Hui Zhao, Zhi-Geng Li, Nan-Yue Wang, Li-Min Wang
OBJECTIVE: To evaluate the effectiveness and safety of Chinese herbs in the treatment of sub-health systematically. METHODS: Nine databases were systematically and extensively searched to collect randomized controlled trials (RCTs) about Chinese herbs in the treatment of sub-health. The outcomes included overall effective rate, main symptoms, quality of life, etc. Literature screening, data extraction and quality assessment were conducted according to Cochrane Handbook 5...
June 18, 2018: Chinese Journal of Integrative Medicine
Xue-Wei Pan, Xiao-Guang Zhang, Xia-Chan Chen, Qi Lu, Ying-Si Hu, Li-Ya Han, Jian-le Zheng, Jie Jin, Guo-Qing Zheng
OBJECTIVE: To investigate the prevalence and spectrum of complementary and alternative medicine (CAM) application and its related-factors in Parkinson's disease (PD) patients in China. METHODS: A structured questionnaire regarding the use of CAMs was administered to PD patients by face-to-face interview. Demographic and social variables, clinical characteristics and treatments, and the related factors of PD were also surveyed. RESULTS: Ninety out of 113 patients (79...
June 18, 2018: Chinese Journal of Integrative Medicine
Sheng-Huang Wang, Lin Chu, Zhao Xu, Hong-Lin Zhou, Jiang-Fei Chen, Huang-Fu Ning
OBJECTIVE: To observe the immediate effect and safety of Shexiang Tongxin dropping pills ( , STDP) on patients with coronary slow flow (CSF), and furthermore, to explore new evidence for the use of Chinese medicine in treating ischemic chest pain. METHODS: Coronary angiography (CAG) with corrected thrombolysis in myocardial infarction (TIMI) frame count (CTFC) was applied (collected at 30 frames/s). The treatment group included 22 CSF patients, while the control group included 22 individuals with normal coronary flow...
June 18, 2018: Chinese Journal of Integrative Medicine
Si-Zhou Huang, Wang-Yu Liu, Yue Huang, A-Ling Shen, Li-Ya Liu, Jun Peng
OBJECTIVE: To investigate the effects of ethanol extract of Patrinia scabiosaefolia (EEPS) on chemo-resistance of colorectal cancer cells (CRC) and explore the possible molecular mechanisms. METHODS: 5-fluorouracil (5-FU)-resistant human colorectal carcinoma cell line (HCT-8/5-FU) and its parental cells HCT-8 were treated with EEPS (0, 0.25, 0.50, 1 or 2 mg/mL), or 5-FU (0, 100, 200, 400, 800 or 1600 μmol/L). The 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay was performed to evaluate the cell viability...
June 8, 2018: Chinese Journal of Integrative Medicine
Jian Ying, Min-Jie Zhou, Hai-Yong Chen, Lei Chen, Wei Zhang, Jun Ji, Chao Yu, Zhang-Jin Zhang
OBJECTIVE: To evaluate the efficacy and safety of essential oil treatment for type III chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). METHODS: A randomized controlled trial was conducted from December 2014 to October 2015. Seventy type III CP/CPPS patients were assigned to the essential oil (35 cases) or almond oil control (35 cases) group by a random number table. The oil was smeared by self-massage on the suprapubic and sacral region once a day for 4 weeks...
June 8, 2018: Chinese Journal of Integrative Medicine
Xiao-Yan Lu, Hao Xu, Tie Zhao, Geng Li
OBJECTIVES: To study the characteristics of serum metabonomics in coronary heart disease (CHD) patients diagnosed as phlegm or blood stasis pattern and explore effects of formula-pattern correspondence treatment. METHODS: A total of 102 stable CHD patients were enrolled and divided into phlegm group (P group, n=52) and blood stasis group (BS group, n=50) according to pattern identifification. Gualou Xiebai Banxia Decoction (, GXBD) and Xuefu Zhuyu Decoction (, XZD) were used as drug interventions...
June 8, 2018: Chinese Journal of Integrative Medicine
Hui Ye, Zong-Ming Shi, Yao Chen, Jing Yu, Xue-Zhi Zhang
Helicobacter pylori (H. pylori) treatment requires the development of more effective therapies, mainly owing to the challenges posed by the bacterial resistance to antibiotics. In China, critically high infection and antibiotic resistance rates have limited the application of classic H. pylori eradication therapies. Consequently, researchers are attempting to find new solutions by drawing from traditional medicine. This article reviews basic scientific and clinical progress in the use of integrated Chinese and Western medicine (IM) to treat H...
June 8, 2018: Chinese Journal of Integrative Medicine
Fang-Jiao Song, Ke-Wu Zeng, Jin-Feng Chen, Yuan Li, Xiao-Min Song, Peng-Fei Tu, Xue-Mei Wang
OBJECTIVE: To investigate the anti-neuroinflammation effect of extract of Fructus Schisandrae chinensis (EFSC) on lipopolysaccharide (LPS)-induced BV-2 cells and the possible involved mechanisms. METHODS: Primary cortical neurons were isolated from embryonic (E17-18) cortices of Institute of Cancer Research (ICR) mouse fetuses. Primary microglia and astroglia were isolated from the frontal cortices of newborn ICR mouse. Different cells were cultured in specific culture medium...
May 22, 2018: Chinese Journal of Integrative Medicine
Tong Zhang, Wen-Ting He, Ming-Jie Zi, Gang Song, Dan-Hui Yi, Yu-Fei Yang
OBJECTIVE: To investigate the efficacy of integrated Chinese and Western medicine (IM) in the treatment of metastatic colorectal cancer (mCRC) in a cohort study. METHODS: The survival outcome of patients receiving IM was compared with that of patients receiving Western medicine alone. The study design was adopted with "continuous administration of Chinese medicine for ⩾ 3 months" as the exposure factor. Patients who met this exposure factor were assigned to the IM cohort (Group A, 110 patients)...
May 22, 2018: Chinese Journal of Integrative Medicine
Hao-Jiang Zuo, Shan Liu, Chun Yan, Li-Man Li, Xiao-Fang Pei
OBJECTIVE: To examine the effect of the aqueous extract of Ligustrum robustum on tumor growth in vitro and in vivo and explore the possible molecular mechanisms. METHODS: In in vitro study, cell viabilities of human cervical carcinoma cells (HeLa), human breast cancer cells (MCF-7), human prostate cancer cells (PC-3), human hepatoma cells (7721) and human colon carcinoma cells (SW480) were evaluated with cell counting kit-8. For L. robustum-treated Hela cells, early or late apoptosis were evaluated by annexin V/PI staining...
May 22, 2018: Chinese Journal of Integrative Medicine
Ji Cui, Li-Ping Tu, Jian-Feng Zhang, Shao-Liang Zhang, Zhi-Feng Zhang, Jia-Tuo Xu
OBJECTIVE: To collect and analyze multi-dimensional pulse diagram features with the array sensor of a pressure profile system (PPS) and study the characteristic parameters of the new multi-dimensional pulse diagram by pulse diagram analysis technology. METHODS: The pulse signals at the Guan position of left wrist were acquired from 105 volunteers at the Shanghai University of Traditional Chinese Medicine. We obtained the pulse data using an array sensor with 3×4 channels...
May 22, 2018: Chinese Journal of Integrative Medicine
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