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Chinese Journal of Integrative Medicine

Qin Dai, Pei-Qing Zhang, Xiao-Qin Wang, Li-Fang Nie, Xiao-Jun Fu, Wen Peng, Yi Wang, Jun Li, Yue-Ping Bi, Xiu-Hua Mi, Min Yuan, Li-Qun He
OBJECTIVE: To explore the therapeutic effect of Yishen Qufeng Shengshi Recipe (, YQSR) in patients with glomerular proteinuria. METHODS: A total of 145 patients with glomerular proteinuria were selected and randomly assigned to the treatment group (108 cases) and the control group (37 cases) according to a random number table in a ratio of 3:1. All patients received conventional and symptomatic treatment. In addition, patients in the treatment and control groups were given YQSR (200 mL, twice per day, orally) and losartan (50 mg/d orally), respectively for 6 months...
November 17, 2017: Chinese Journal of Integrative Medicine
Jang-Han Bae, Boncho Ku, Young Ju Jeon, Hyunho Kim, Jihye Kim, Haebeom Lee, Jong Yeol Kim, Jaeuk U Kim
OBJECTIVE: To investigate the changes in radial pulse induced by thermal stresses (TSs). METHODS: Sixty subjects were enrolled. Using an open-label, 2×2 crossover randomization design, both feet of each subject were immersed in 15 °C water for cold stress (CS) and in 40 °C water for heat stress (HS) for 5 min each. Radial pulse, respiration and electrocardiogram (ECG) signals were recorded before, during and immediately after the TSs. RESULTS: The analysis of heart rate variability revealed that CS increased the low-frequency (LF) and high-frequency (HF) components (P <0...
November 17, 2017: Chinese Journal of Integrative Medicine
Wan-Tai Dang, Wen-Guang Xie, Jing-Guo Zhou
OBJECTIVE: To study the expression level and role of apoptosis-associated speck-like protein containing a caspase recruitment domain (PYCARD) gene transcript variant mRNA in peripheral blood mononuclear cells (PBMCs) of primary gout (PG) patients with different Chinese medicine (CM) syndromes. METHODS: The expressions of PYCARD gene transcript variant mRNA and interleukin-1β (IL-1β) mRNA in PBMCs were investigated in 96 PG patients with acute phase (APPG, 44 cases) and non-acute phase (NAPPG, 52 cases) and 30 healthy controls (HCs) by reverse transcription-polymerase chain reaction (PCR) and/or realtime quantitative PCR...
October 30, 2017: Chinese Journal of Integrative Medicine
Xiao-Ming Liu, Yong-Bin Wang, Qian Wu, Zhong-Rui Bian, Xiao-Wen Che
OBJECTIVE: To investigate the effects of ligustrazine (LTZ) on airway inflammation in a mouse model of neutrophilic asthma (NA). METHODS: Forty healthy C57BL/6 female mice were randomly divided into 4 groups using a random number table, including the normal control, NA, LTZ and dexamethasone (DXM) groups, with 10 rats in each group. The NA mice model was established by the method of ovalbumin combined with lipopolysaccharide sensitization. At 0.5 h before each challenge, LTZ and DXM groups were intraperitoneally injected with LTZ (80 mg/kg) or DXM (0...
October 30, 2017: Chinese Journal of Integrative Medicine
Yue Wang, Lu Xiao, Wei Mu, Hai-Long Yu, Shuo Zhang, Gui-Hua Tian, Hong-Cai Shang
OBJECTIVE: To provide evidence-based recommendations for clinical application and provoke thoughts for future researchers by conducting a comprehensive summary and evaluation of the current evidence profifile for the role of Chinese medicine (CM) in treating myocardial infarction (MI). METHODS: Online databases including PubMed, EMBase, Cochrane Library, Chinese National Knowledge Infrastructure (CNKI), Chinese Biomedical Medicine (CBM), VIP Journal Integration Platform, and Wanfang database were systematically searched for literatures on CM in treating MI...
October 27, 2017: Chinese Journal of Integrative Medicine
Si-Wei Li, Xue Feng, Hao Xu, Ke-Ji Chen
OBJECTIVE: To detect the anticoagulation and antiplatelet effects of different concentrations of puerarin, heparin sodium and tirofiban hydrochloride on the blood samples of healthy volunteers by Sonoclot coagulation and platelet function analyzer. METHODS: Peripheral blood samples were extracted from 20 healthy volunteers, followed by adding different concentrations of puerarin, heparin sodium and tirofiban hydrochloride. Samples were detected for activated clotting time (ACT), clot rate (CR) and platelet function (PF) by Sonoclot coagulation and platelet function analyzer instrument...
October 25, 2017: Chinese Journal of Integrative Medicine
Er-Liang Wang, Xiao Chen
Chinese medical classics are important carriers for the inheritance, innovation and development of academic thoughts of Chinese medicine (CM), containing rich thoughts on diagnosis and treatment as well as therapeutic principles of CM. The international exchange of CM has a very long history. With the development of society, Western scholars in modern times are deepening their researches on Chinese medical classics. This would provide a new way for promoting CM in Western countries to investigate researches made by famed American scholars and their academic viewpoints...
October 24, 2017: Chinese Journal of Integrative Medicine
Hai-Xiang Hu, Jing Sun, Ya-Jing Gao, Hong Fang, Shao-Qiang Xu, Jing Dong, Li-Zhao Wei, Shao-Bo Luo, Chuan-Yun Shen, Qi-Long Zhang, Ya-Lan Xie
OBJECTIVE: To investigate the effect of a modified Wuzi Yanzong Pill (, WZYZP) on the male rats' testis after microwave radiation, as well as its potential mechanism. METHODS: Forty-five male rats were randomly assigned to three groups: the control group, the radiation group, and the WZYZP group. The rats in the radiation group and WZYZP group were exposed to microwave radiation for 15 min once, while the rats in the control group were not exposed to any radiation...
October 24, 2017: Chinese Journal of Integrative Medicine
Meng Li, Miao-Miao Wang, Xiu-Wei Guo, Chao-Yong Wu, Dao-Rui Li, Xing Zhang, Pei-Tong Zhang
OBJECTIVE: To assess the efficacy of Chinese medicine (CM) on patients with pancreatic cancer (PC) in a retrospective population-based study. METHODS: Between January 1, 2013, and August 30, 2016, according to whether received Western medicine treatment, the patients were included into either integrative medicine (IM) group or CM group. All enrolled patients were orally administrated with Gexia Zhuyu Decoction () or Liujun Ermu Decoction () by syndrome differentiation, twice a day, last for at least 2 months...
October 24, 2017: Chinese Journal of Integrative Medicine
Xiu-Wei Guo, Nai-Dong Hu, Gui-Zhi Sun, Meng Li, Pei-Tong Zhang
OBJECTIVE: To assist decision-makers interpret and choose among conflicting meta-analyses, as well as to offer treatment recommendations based on current best evidence by performing a systematic review of overlapping meta-analyses regarding Shenyi Capsule (, SC) plus chemotherapy versus chemotherapy of non-small cell lung cancer (NSCLC). METHODS: A literature search was conducted to select systematic reviews comparing SC plus chemotherapy with chemotherapy for NSCLC...
October 18, 2017: Chinese Journal of Integrative Medicine
Mandana Behbahani
OBJECTIVE: To test the anti-human immunodeficiency virus (HIV) activity of pure compounds isolated from aerial part extracts of Alhaji maurorum and its parasite Cuscuta kotchiana. METHODS: The anti-HIV-1 and anti-HIV-2 activities of these extracts were performed by use of quantitative polymerase chain reaction assay and high pure viral nucleic acid kit. The most active fractions against HIV-1 were detected by nuclear magnetic resonance as pratensein and pratensein glycoside respectively in A...
October 18, 2017: Chinese Journal of Integrative Medicine
Shi-Tang Ma, Cheng-Tao Feng, You-Xi Xiong, Xiao-Lin Zhang, Cheng-Gui Miao, Hao Yu
OBJECTIVE: To elucidate the action mechanism of Xingnaojing Injection (, XNJI) for sepsis, and to target screen the potential bioactive ingredients. METHODS: An integrated protocol that combines in silico target screen (molecular docking) and database mapping was employed to find the potential inhibitors from XNJI for the sepsis-related targets and to establish the compound-target (C-T) interaction network. The XNJI's bioactive components database was investigated and the sepsis-associated targets were comprehensively constructed; the 3D structure of adenosine receptor A2a and 5-lipoxygenase proteins were established and evaluated with homology modeling method; system network pharmacology for sepsis treatment was studied between the bioactive ingredients and the sepsis targets using computational biology methods to distinguish inhibitors from non inhibitors for the selected sepsis-related targets and C-T network construction...
October 17, 2017: Chinese Journal of Integrative Medicine
Yan Liu, Li-Yun He, Tian-Cai Wen, Shi-Yan Yan, Wen-Jing Bai, Bao-Yan Liu
OBJECTIVE: To determine whether patterns of enterovirus 71 (EV71)-associated hand, foot, and mouth disease (HFMD) were classified based on symptoms and signs, and explore whether individual characteristics were correlated with membership in particular pattern. METHODS: Symptom-based latent class analysis (LCA) was used to determine whether patterns of EV71-HFMD existed in a sample of 433 cases from a clinical data warehouse system. Logistic regression was then performed to explore whether demographic, and laboratory data were associated with pattern membership...
October 17, 2017: Chinese Journal of Integrative Medicine
Min Li, Ke Wang, Wen-Ting Su, Jun Jia, Xiao-Min Wang
OBJECTIVE: To explore the possible underlying mechanism by investigating the effect of electroacupuncture (EA) treatment on the primary motor cortex and striatum in a unilateral 6-hydroxydopamine (6-OHDA) induced rat Parkinson's disease (PD) model. METHODS: Male Sprague-Dawley rats were randomly divided into sham group (n=16), model group (n=14), and EA group (n=14). EA stimulation at Dazhui (GV 14) and Baihui (GV20) was applied to PD rats in the EA group for 4 weeks...
October 6, 2017: Chinese Journal of Integrative Medicine
Yu Zhang, Li Hou, Xin-Yi Chen
OBJECTIVE: To investigate the effects of Compound Zhebei Granule (, CZG) combined with doxorubicin hydrochloride (adriamycin, ADM) on specific surface antigens in mice with KG-1a transplanted cells. METHODS: A subcutaneous tumor xenograft model was established by injection of the acute myeloid leukemia cell line KG-1a into the axillary flanks of BALB/c-nude mice. Twenty-four tumor bearing mice were divided into 4 groups according to a random number table, including normal saline control group, ADM group, high-dose CZG group, and mid-dose CZG group, with 6 mice in each group...
October 6, 2017: Chinese Journal of Integrative Medicine
Kai-Liang Fan, Jun-Hui Wang, Li Kong, Fei-Hu Zhang, Hao Hao, Hao Zhao, Zheng-Yun Tian, Ming-Xin Yin, Hua Fang, Hui-Hui Yang, Yang Liu
OBJECTIVE: To investigate the hemodynamic effect of Shen-Fu Injection (, SFI) in early volume resuscitation treated septic shock patients by monitoring pulse indicator continuous cardiac output (PICCO). METHODS: All septic shock patients admitted in the Intensive Care Unit of the Affiliated Hospital of Shandong University of Traditional Chinese Medicine from January 1st, 2014 to December 31th, 2015, were reviewed, and totally 65 were enrolled in this study. They were assigned to SFI group (33 cases) and control group (32 cases)...
October 6, 2017: Chinese Journal of Integrative Medicine
Wen-Ya Huang, Xin Zou, Fu-Er Lu, Chu Zhang, Yan-Lin Ren, Li-Jun Xu, Kai-Fu Wang, Hui Dong
OBJECTIVE: To explore the effect and mechanism of Jiaotai Pill (, JTW) on intestinal mucosal damage in rats with chronic partial sleep deprivation (PSD). METHODS: Obesity resistant (OR) rats were selected, and underwent 4 h PSD by being exposed to environmental noise for 4 weeks. During the whole PSD period, JTW and estazolam were orally given to the rats respectively in the treating groups. Plasma concentration of lipopolysaccharide (LPS) which is the marker of gut-origin endotoxemia was examined...
October 6, 2017: Chinese Journal of Integrative Medicine
Shu-Ling Wang, Zhen-Kun Zhao, Jian-Feng Sun, Yun-Ting Sun, Xiao-Qing Pang, Zhao-Wu Zeng, Tian Xie
The chemical compositions of Anemone raddeana Rhizome, a kind of traditional Chinese medicine, were reviewed, along with its bioactivity and pharmacological properties and method improvements of extracting and detecting triterpenoid saponins. A. raddeana Rhizome is used to treat neuralgia and rheumatism, and is rich in triterpenoid saponins, most of which are pentacyclic, with oleanane as the nucleus. So far, 37 triterpenoid saponins have been determined from the herb. Its reported bioactivity and pharmacological properties have been described as anticancerous, antimicrobial, anti-inflammatory, analgesic, antipyretic, anticonvulsive, antihistaminic, and sedative...
October 6, 2017: Chinese Journal of Integrative Medicine
Byung-Wook Lee, Hyeon-Yeop Lee, Kwang-Ho Heo, Hyun-Woo Cho, Man-Suk Hwang, In Heo, Byung-Cheul Shin, Eui-Hyoung Hwang
OBJECTIVE: To obtain fundamental information for the standardization of herbal medicine in Korea. METHODS: We analyzed the herbal medicine prescription data of patients at the Pusan National University Korean Medicine Hospital from March 2010 to February 2013. We used the Dongui-Bogam (Dong Yi Bao Jian) to classify prescribed herbal medicines. RESULTS: The study revealed that the most frequently prescribed herbal medicine was 'Liuwei Dihuang Pill (LWDHP, )' which was used for invigorating 'Shen (Kidndy)-yin'...
October 6, 2017: Chinese Journal of Integrative Medicine
Xue-Zhong Gong
No abstract text is available yet for this article.
October 6, 2017: Chinese Journal of Integrative Medicine
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