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Chinese Journal of Integrative Medicine

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https://www.readbyqxmd.com/read/28283936/in-vivo-and-in-vitro-anti-inflammatory-effects-of-ethanol-fraction-from-periploca-forrestii-schltr
#1
Li Dong, Yun Zhang, Xia Wang, Yong-Xi Dong, Lin Zheng, Yong-Jun Li, Jing-Man Ni
OBJECTIVE: To determine the anti-inflammatory effects of an ethanol fraction of Periploca forrestii Schltr. (EFPF) and to investigate the potential mechanisms underlying in vivo and in vitro models. METHODS: The antiinflammatory effects of EFPF were evaluated using the xylene-induced mouse ear edema and carrageenan-induced rat paw edema models in vivo. In vitro, RAW264.7 cells were exposed to 0-800 μg/mL EFPF and the cell viability was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay...
March 10, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28251475/chinese-medicines-reported-to-have-effects-on-contact-dermatitis-in-the-last-20-years
#2
REVIEW
Youngchul Jung, Byungju Kim, Mi Heon Ryu, Hyungwoo Kim
Contact dermatitis (CD) is one of the most common skin diseases in industrialized countries. Chinese medicines (CMs) have been investigated worldwide as complementary and alternative medicines for corticosteroids, which are the first choice for treatment of inflammatory skin diseases owing to their favorable efficacy. This article describes the CMs that have been reported to have anti-dermatitis effects against CD in the last 20 years.
March 2, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28197938/clinical-efficacy-and-safety-of-bathing-with-chinese-medicine-taohong-siwu-decoction-for-treatment-of-diffuse-cutaneous-systemic-sclerosis-a-randomized-placebo-controlled-trial
#3
Jing Zhou, Dong Yang, Shu-Hong Zhou, Jin-Ping Wang, Yue-Shu Liu, Shu-Lan Wang
OBJECTIVE: To examine the efficacy and safety of bathing therapy with Taohong Siwu Decoction (, TSD) in the treatment of early-stage, mild-moderate diffuse cutaneous systemic sclerosis (dcSSc). METHODS: This randomized, placebo-controlled trial enrolled 148 men and women (18-60 years) with dcSSc (disease duration ≤12 months) and baseline modified Rodnan skin score (MRSS) ≥10. Patients were randomized into a TSD group (71 cases bathing with TSD plus oral prednisone) or control group (71 cases bathing with placebo plus oral prednisone)...
February 15, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28197937/association-of-platelet-activating-factor-receptor-gene-rs5938-g-t-and-rs313152-t-c-polymorphisms-with-coronary-heart-disease-and-blood-stasis-syndrome-in-a-chinese-han-population
#4
Guo-Hua Zheng, Shang-Quan Xiong, Hai-Ying Chen, Li-Juan Mei, Ting Wang
OBJECTIVE: To explore the association of the platelet-activating factor receptor (PAFR) gene rs5938, rs313152 and rs76744145 polymorphisms with coronary heart disease (CHD) and blood stasis syndrome (BSS) of CHD in Chinese Han population. METHODS: A total of 570 CHD patients (299 with BSS and 271 with non-BSS) and 317 controls were enrolled. The PAFR gene rs5938, rs313152 and rs76744145 polymorphisms were genotyped using the multiplex SNaPshot technology. The statistical analysis was conducted using a multiple variable logistic regression model...
February 15, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28197936/salvianolic-acid-a-protects-neonatal-cardiomyocytes-against-hypoxia-reoxygenation-induced-injury-by-preserving-mitochondrial-function-and-activating-akt-gsk-3%C3%AE-signals
#5
Xue-Li Li, Ji-Ping Fan, Jian-Xun Liu, Li-Na Liang
OBJECTIVE: To investigate the effects of salvianolic acid A (SAA) on cardiomyocyte apoptosis and mitochondrial dysfunction in response to hypoxia/reoxygenation (H/R) injury and to determine whether the Akt signaling pathway might play a role. METHODS: An in vitro model of H/R injury was used to study outcomes on primary cultured neonatal rat cardiomyocytes. The cardiomyocytes were treated with 12.5, 25, 50 μg/mL SAA at the beginning of hypoxia and reoxygenation, respectively...
February 15, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28197935/anti-inflammatory-effect-of-total-saponin-fraction-from-dioscorea-nipponica-makino-on-gouty-arthritis-and-its-influence-on-nalp3-inflammasome
#6
Qi Zhou, Dong-Hua Yu, Ning Zhang, Shu-Min Liu
OBJECTIVE: To investigate the mechanism of Chinese herbal medicine Dioscorea nipponica for the treatment of monosodium urate crystals-induced gouty arthritis (GA) in rats. METHODS: Sixty male Wistar rats were divided into 6 groups: normal, model, indomethacin and three total saponin (900, 300 and 100 mg/kg) groups. The liver, kidney and serum levels of lysosomal enzymes, antioxidant capacities, and inflammatory factors were measured. In addition, the mRNA and protein levels of the NALP3 inflammasome components in the mononuclear cells of rats' peripheral blood were analyzed using real-time polymerase chain reaction and Western blotting methods, respectively...
February 15, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28197934/fuzheng-huayu-formula-prevents-rat-renal-interstitial-fibrosis-induced-by-hgcl2-via-antioxidative-stress-and-down-regulation-of-nuclear-factor-kappa-b-activity
#7
Ji-Li Yuan, Yan-Yan Tao, Qing-Lan Wang, Li Shen, Cheng-Hai Liu
OBJECTIVE: To investigate the mechanism of action of Fuzheng Huayu Formula (, FZHY) against renal interstitial fibrosis (RIF) relating to oxidative injury and nuclear factor-kappa B (NF-κB) activity. METHODS: Thirty-two Sprague-Dawley rats were randomly divided into 3 groups: control group, model group and FZHY treatment group. The RIF model was induced by oral administration of HgCl2 at a dose of 8 mg/kg body weight once a day for 9 weeks. Meanwhile, rats in FZHY treatment group orally took FZHY at a dose of 4...
February 15, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28197933/garlic-extract-attenuates-immobilization-stress-induced-alterations-in-plasma-antioxidant-oxidant-parameters-and-hepatic-function-in-rats
#8
Syed Kashif Zaidi, Shakeel Ahmed Ansari, Shams Tabrez, Md Nasrul Hoda, Ghulam Md Ashraf, Mohd Shahnawaz Khan, Sultan Alnohair, Naheed Banu, Mohammed Hussain Al-Qahtani
OBJECTIVE: To investigate the oxidative stress induced by 6 h of immobilization stress in Albino Wistar rats. Further, the pre- and post-treatment of aqueous garlic extract was studied to evaluate its preventive and curative efficacy on stress-induced altered oxidative parameters in rats. METHODS: Albino Wistar rats were exposed to 6 h of immobilization stress, and received garlic extract (100 mg/kg body weight) treatment pre- or post-stress exposure. The oxidative status of plasma after various treatments were evaluated by determining the levels of reduced glutathione, glucose, uric acid, thiobarbituric acid reactive substances, aspartate aminotransferase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP) and the activities of superoxide dismutase, catalase and glutathione-S-transferase by standardized procedures...
February 15, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28120209/differential-proteomics-analysis-of-endometriosis-in-blood-stasis-syndrome
#9
Yi Wen, Yan Wang, Ting-Ting Feng, Shao-Bin Wei
OBJECTIVE: To investigate the innate characters of 3 endometriosis (EMT) syndromes, blood stasis (BS), qi stagnation and blood stasis (QSBS) as well as Shen (Kidney) deficiency and blood stasis (KDBS) in terms of proteomics, lay a molecular biological basis for the differentiation of various blood stasis syndromes of EMT, establish a EMT microscopic syndrome differentiation and diagnosis system in terms of proteomics, discover the evolution principles and therapeutic targets of these EMT syndromes, and search their significant molecular markers and genetic intervention targets...
January 24, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28120208/huannao-yicong-formula-regulates-%C3%AE-secretase-activity-through-aph-1-and-pen-2-gene-ragulation-pathways-in-hippocampus-of-app-ps1-double-transgenic-mice
#10
Zhi-Yong Wang, Jian-Gang Liu, Yun Wei, Mei-Xia Liu, Qi Wang, Lin Liang, Hui-Min Yang, Hao Li
OBJECTIVE: To observe the effects of Huannao Yicong Formula (, HYF) on learning and memory and it's regulating effect on γ-secretase related anterior pharynx defective 1 (APH-1), presenilin enhancer-2 (PEN-2) signaling pathway, so as to discuss and further clarify the mechanism of HYF on Alzheimer's disease. METHODS: Sixty APP/PS1 transgenic mice, randomly allocated into 4 groups, the model group, the donepezil group (0.65 mg/kg), HYF low-dose group (HYF-L, 5.46 g/kg) and HYF high-dose group (HYF-H, 10...
January 24, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28120207/a-review-on-medicinal-uses-analytical-techniques-and-pharmacological-activities-of-strychnos-nux-vomica-linn-a-concise-report
#11
REVIEW
Kanika Patel, Damiki Laloo, Gireesh Kumar Singh, Manoj Gadewar, Dinesh Kumar Patel
The purpose of this review is to provide comprehensive and relevant information on the utilization and pharmacological activities of Strychnos nux-vomica Linn. (Loganiaceae), used for the treatment of various diseases. Strychnos nux-vomica is an evergreen tree native to Southeast Asia and its dried seeds are used for the treatment of neurodisorders, arthritis and vomiting. The different use of this plant as herbal remedy in Chinese medicine is also reported in the literature. Strychnine and brucine are major pharmacologically active phytoconstituents of Strychnos nux-vomica, which are central nervous stimulant, but also found to be poisonous at high dosage...
January 24, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28116663/effect-of-paeotang-on-tumor-necrosis-factor-%C3%AE-induced-vascular-inflammation-in-human-umbilical-vein-endothelial-cells
#12
Dae Hwan Kim, So Min Lee, Yun Jung Lee, Jung Joo Yoon, Rui Tan, Yun Cho Yu, Dae Gill Kang, Ho Sub Lee
OBJECTIVE: To investigate whether Paeotang (10-50 μg/mL) suppresses tumor necrosis factor α (TNF-α)-induced vascular inflammatory processes in human umbilical vein endothelial cells (HUVEC). METHODS: The ingredients composed of Paeotang include Glycyrrhiza glabra, Zingiber officinale, Cinnamomum zeylanuicum, Salvia miltiorrhiza, Prunus persica, Paeonia szechuanica, Poria cocos and Cynanchum wilfordii. Herbs were mixed according to equal ratio of weight and ground into a crude powder...
January 24, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28116662/recommendations-for-acupuncture-in-clinical-practice-guidelines-of-the-national-guideline-clearinghouse
#13
Yao Guo, Hong Zhao, Fang Wang, Si-Nuo Li, Yu-Xiu Sun, Ming-Juan Hang, Bao-Yan Liu
OBJECTIVE: To organize the clinical practice guidelines (CPGs) related to acupuncture included in the National Guideline Clearinghouse (NGC) to systematically summarize the diseases and disorders most commonly treated with acupuncture, the strength of recommendations for acupuncture and the quality of evidence. METHODS: The NGC database was systematically searched for guidelines that included acupuncture as an intervention. Two independent reviewers studied the summaries and the full texts of the guidelines and included guidelines based on the inclusion and exclusion criteria...
January 24, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28116661/digital-education-and-dynamic-assessment-of-tongue-diagnosis-based-on-mashup-technique
#14
Chin-Chuan Tsai, Yen-Cheng Lo, John Y Chiang, Natsagdorj Sainbuyan
OBJECTIVE: To assess the digital education and dynamic assessment of tongue diagnosis based on Mashup technique (DEDATD) according to specifific user's answering pattern, and provide pertinent information tailored to user's specifific needs supplemented by the teaching materials constantly updated through the Mashup technique. METHODS: Fifty-four undergraduate students were tested with DEDATD developed. The effificacy of the DEDATD was evaluated based on the pre- and post-test performance, with interleaving training sessions targeting on the weakness of the student under test...
January 24, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28116660/salvianolic-acid-b-attenuates-oxidized-low-density-lipoprotein-induced-endothelial-cell-apoptosis-through-inhibition-of-oxidative-stress-p53-and-caspase-3-pathways
#15
Hong-Mei Chen, Hao Luo, Wen-Bi Zeng, Bin Liu, Jia-Cheng Huang, Min Liu, Yan-Jin Zeng, Qiang Zheng, Ji-Qiang Li, Xue-Gang Sun, Ying-Chun Zhou
OBJECTIVE: To investigate the effect of salvianolic acid B (Sal B) on oxidized low-density lipoprotein (ox-LDL)-induced human umbilical vein endothelial cells (HUVECs) apoptosis and the possible mechanism. METHODS: HUVECs were divided into 6 groups, including control group, ox-LDL group, vitamin C group (positive control), and 5, 10 and 20 μg/mL Sal B groups. Cell viability of HUVECs was determined by 3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay...
January 24, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28116659/effect-of-rhizoma-polygoni-cuspidati-and-ramulus-cinnamomi-compatibility-on-uric-acid-metabolism-and-urinary-neutrophil-gelatinase-associated-lipocalin-and-kidney-injury-molecule-1-in-rats-with-hyperuricemia
#16
Bin Han, Chun-Xia Zhu, Wan Shi, Hui-Zhu Huang, Xu-Guang Hu, Xiao-Ming Zhou, Ming Lei, Zhong Li
OBJECTIVE: To explore the effects of Rhizoma Polygoni Cuspidati and Ramulus Cinnamomi compatibility (PR) on uric acid metabolism and the expression of urinary neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) in rats with hyperuricemia. METHODS: Seventy male Sprague Dawley (SD) rats were randomly divided into 7 groups with 10 rats per group, including the normal group, model group, allopurinol group, benzbromarone group and PR groups at 3 doses (3...
January 24, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28108911/traditional-chinese-medicine-for-modern-treatment-of-parkinson-s-disease
#17
REVIEW
Lu Han, Yuan-Hong Xie, Rong Wu, Chen Chen, Yan Zhang, Xiao-Ping Wang
Parkinson's disease (PD) is a chronic and progressive degenerative disorder of brain commonly seen among the elderly. As conventionally medical therapy is of limited relief and potential side effects, complementary and alternative medicine (CAM) has attracted growing public and professional attention. Therapies such as acupuncture, musical/rhythmic therapy and deep brain stimulation have been gradually proved positively in clinic. In this review, we retrospected the scientific or evidence-based-medicine advances of application and research for modern treatment of PD by CAM, especially traditional Chinese medicine in categories...
January 20, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28083812/effect-of-dendrobium-officinale-on-d-galactose-induced-aging-mice
#18
Chu-Yan Liang, Ying-Min Liang, Hua-Zhen Liu, Dong-Mei Zhu, Shao-Zhen Hou, Ya-Yun Wu, Song Huang, Xiao-Ping Lai
OBJECTIVE: To examine the effect of Dendrobium officinale (DO) on D-galactose-induced aging mice. METHODS: Aging mice was induced by D-galactose at 0.125 g/kg for 10 weeks through subcutaneous injection except for the negative control group. After 10 days, according to complete random design, the aging modeling mice were randomized into 4 groups: aging control group (10 ML·kg(-1)·d(-1)) of distilled water), positive control group (vitamin B6 and ganodema lucidum tablets with a dose of 1 tablet/kg), DO-1 treatment group (DO juice with a dose of 1 g/kg), DO-2 treatment group (DO Polysaccharide with a dose of 0...
January 12, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28035542/effect-of-compound-zhuye-shigao-granule-on-acute-radiation-induced-esophagitis-in-cancer-patients-a-randomized-controlled-trial
#19
Li-Juan Wang, Jun-Zhang Lu, Bo-Ning Cai, Ming-Wei Li, Bao-Lin Qu
OBJECTIVE: To observe the effificacy and safety of the Chinese medicine (CM) Compound Zhuye Shigao Granule (, CZSG) on acute radiation-induced esophagitis (ARIE) in cancer patients. METHODS: In a blinded, randomized, Kangfuxin Solution (, KFX)-controlled, single-centre clinical trial, 120 patients with lung, esophagus or mediastinal cancer were prospectively enrolled and assigned to the treatment group (60 cases) and control group (60 cases) by the random number table method...
December 29, 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28035541/effect-of-artemisia-annua-extract-on-treating-active-rheumatoid-arthritis-a-randomized-controlled-trial
#20
Min Yang, Ming-Yang Guo, Yong Luo, Ming-Dong Yun, Jiao Yan, Tao Liu, Chang-Hong Xiao
OBJECTIVE: To investigate the effect and safety of the complementary use of the extract of Artemisia annua L. (EAA) on treating active rheumatoid arthritis (RA). METHODS: A randomized controlled clinical trial was performed. All the 159 participates with active RA were randomly assigned to the control group (80 cases) and EAA group (79 cases). In the control group, patients were medicated with leflflunomide and methotrexate for 48 weeks; and patients in the EAA group were administrated with leflflunomide, methotrexate plus EAA (30 g/d)...
December 29, 2016: Chinese Journal of Integrative Medicine
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