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Chinese Journal of Integrative Medicine

Chien-Ying Lee, Hung-Che Shih, Min-Chien Yu, Ming-Yung Lee, Ya-Lan Chang, Ya-Yun Lai, Yi-Ching Lee, Yu-Hsiang Kuan, Chun-Che Lin
OBJECTIVE: To investigate whether three strains of probiotics, L. acidophilus, L. rhamnosus, and L. sporogenes, had significant inhibitive effects on Helicobacter pylori (H. pylori). METHODS: This is a 4-week, randomly assigned, parallel-group, doubled-blind, and placebo-controlled study. Fifty patients with a positive H. pylori infection urea breath test (ΔUBT) result > 10% and without ulcer symptoms were randomized into a treatment group and a placebo group by a computer generated allocation sheet with 1:1...
October 19, 2016: Chinese Journal of Integrative Medicine
Tun-Pin Hsueh, Yu-Chiang Hung, Wen-Long Hu
No abstract text is available yet for this article.
September 27, 2016: Chinese Journal of Integrative Medicine
Yang Wang, Xi Huang, Mei-Zuo Zhong, Ruo-Huang Lu, Zi-An Xia, Rong Fan, Bo Liu, Wei Huang, Ping-Ping Gan
OBJECTIVE: To investigate the effect of Shaoyao Gancao Decoction (, SGD) on the pharmacokinetics of intravenously administered paclitaxel in rats. METHODS: Paclitaxel was intravenously administered to rats (3 mg/kg) with or without the concomitant administration of SGD (752 mg/kg, a single day or 14 consecutive days pretreatment). The paclitaxel in the serum was quantified using a simple and rapid ultra performance liquid chromatography (UPLC) method for the pharmacokinetic study...
September 27, 2016: Chinese Journal of Integrative Medicine
Liu-Xin Qu, Li-Yang Xing, Norman Wanda, Hong Chen, Ming-Ju Li, Song Gao, Ping Li
OBJECTIVE: To evaluate the clinical effect of traditional Chinese spinal orthopedic manipulation (TCSOM) in treating patients with functional abdominal pain syndrome (FAPS) in comparison with Pinaverium Bromide (Dicetel, PBD), and to assess a possible cause for FAPS. METHODS: Eighty patients with FAPS were randomly and equally assigned to the TCSOM group and PBD group according to the random number table. All patients in the TCSOM group were treated with a maximum of 5 times of spinal manipulations...
September 26, 2016: Chinese Journal of Integrative Medicine
Xiao-Li He, Shi-Hui Zhao, Wei You, Yu-Ying Cai, Yan-Yun Wang, Yong-Ming Ye, Bao-Hui Jia
OBJECTIVE: To investigate the preventive treatment effects of electroacupuncture (EA) on cognitive changes and brain damage in senescence-accelerated mouse prone 8 (SAMP8) mice. METHODS: The 5-month-old male SAMP8 and age-matched homologous normal aging mice (SAMR1) were adopted in this study. EA stimulation at Baihui (GV 20) and Yintang (EX-HN 3) was performed every other day for 12 weeks, 4 weeks as a course. Morris water maze test and Nissl-stained with cresyl violet were used for cognitive impairments evaluation and brain morphometric analysis...
September 26, 2016: Chinese Journal of Integrative Medicine
Bo Chen, Ming-Yue Li, Yi Guo, Xue Zhao, Hui-Min Calista Lim
Exosomes are cell-derived vesicles that take part in intercellular signaling. Research has shown that acupuncture is closely related to affecting the functions of the mast cells in the local region of the acupoint, and stimulating the afferent nerve. Mast cells have a connection with the conduction within the meridians, and play an important role in immuno-regulation. The 'synapse-like' connection between the mast cells and nerve endings is the basis for the exchange of information between these two tissues...
September 20, 2016: Chinese Journal of Integrative Medicine
Ai-Jun Sun, Ya-Ping Wang, Bei Gu, Ting-Ping Zheng, Shou-Qing Lin, Wen-Pei Bai, Yang Wei, Shao-Fen Zhang, Ying Zhang
OBJECTIVE: To evaluate the efficacy and safety of Heyan Kuntai Capsule (, HYKT) and hormone therapy (HT) on perimenopausal syndromes (PMSs). METHODS: From 2005 to 2008, 390 women with PMSs were recruited from 4 clinic centers. The inclusion criteria included ages 40 to 60 years, estradiol (E2) below 30 ng/L, and follicle stimulating hormone (FSH) above 40 IU/L, etc. The patients were randomly assigned to HYKT group or HT group by random number table method, administrated HYKT or conjugated estrogen with/without medroxyprogesterone acetate tablets for 12 months...
September 20, 2016: Chinese Journal of Integrative Medicine
Chao-Feng Hu, Li-Ping Sun, Qin-He Yang, Da-Xiang Lu, Sen Luo
OBJECTIVE: To investigate the effect of ginsenosides from stems and leaves of ginseng on ethanolinduced lipid deposition in human L02 hepatocytes. METHODS: L02 cells were exposed to ethanol for 36 h and treated with or without ginsenosides. The viability of L02 cells was evaluated by methylthiazolyldiphenyltetrazolium bromide assay and the triglyceride (TG) content was detected. Lipid droplets were determined by oil red O staining. Intracellular reactive oxygen species (ROS) production and the mitochondrial membrane potential were tested by flow cytometry...
September 10, 2016: Chinese Journal of Integrative Medicine
Qin Yin, Cai-Jun Wu, Jun Yang, Chen-Chen Hang, Chun-Sheng Li
OBJECTIVE: To investigate the effects of Shenfu Injection (, SFI) on cerebral metabolism in a porcine model of cardiac arrest (CA). METHODS: Thirty Wuzhishan minipigs were randomly assigned to the control group (n=6), epinephrine group (EP group, n=12) and Sfigroup (n=12). After 8 min of untreated ventricular fifibrillation (VF), pigs in the EP group or Sfigroup were administered with either EP (0.02 mg/kg) or Sfi(1.0 mL/kg), respectively. After successful resuscitation, cerebrospinal fluid (CSF) levels of glucose, pyruvate, lactate, glutamate and glycerol were measured at 1, 6, 12 and 24 h after recover from spontaneous circulation (ROSC)...
September 10, 2016: Chinese Journal of Integrative Medicine
Keyal Uma, Xin Huang, Bhatta Anil Kumar
The advancement of phytochemical and phytopharmacological sciences has enabled elucidation of the composition and biological activities of several medicinal plant products including plant extract and essential oils. These products have been widely used around the world since ancient times for the treatment of various disorders such as diabetes, hypertension, peptic ulcer disease, microbial infection, sexual disorder and many more. Its popularity in the modern system of medicine is mainly due to their availability and fewer adverse reactions compared to synthetic drugs...
September 3, 2016: Chinese Journal of Integrative Medicine
Jie Yang, Wei-Hong Li, Rong An, Yi-Li Wang, Yan Xu, Jie Chen, Xiao-Fang Wang, Xiao-Bo Zhang, Jing Li, Wei-Jun Ding
OBJECTIVE: To explore the scientific connotation of the discrepant pharmaceutical activities between the head and tail of Angelica sinensis diels (AS), an important herb extensively utilized in Chinese medicine, by the approach of transcriptome sequencing. METHODS: Ten samples of AS were randomly collected in Min County, Gansu Province of China. Transcriptome sequencing of AS was accomplished in a commercial ILLumina HiSeq-2000 platform. The transcriptome of each head and tail of AS were fifixed in a gene chip, and detected under the procedure of Illumina HiSeq-2000...
September 1, 2016: Chinese Journal of Integrative Medicine
Jian Hao, Xiu-Li Ding, Xue Yang, Xiong-Zhi Wu
OBJECTIVE: To study the effects of Prunella vulgaris polysaccharide (PVP) on human breast carcinoma-associated fibroblasts (CAFs). METHODS: Cell viability was detected by 3-[4,5-dimethylthiazol-2-yl]-2,5-(3-carboxymethoxyphenyl)-2-4-sulfophenyl)-2H-tetrazolium (MTS) assay. Wound healing experiment and transwell migration assay were used to investigate the anti-migration effects. Flow cytometry was applied to detect cell apoptosis and cell cycle distribution. Reverse transcription-polymerase chain reaction and enzyme-linked immunosorbent assay were used to detect the expression of basic fifibroblast growth factor (bFGF) in CAFs...
September 1, 2016: Chinese Journal of Integrative Medicine
Jung-Hee Jang, Deuk-Joo Lee, Chang-Hwan Bae, Ki-Tae Ha, Sunoh Kwon, Hi-Joon Park, Dae-Hyun Hahm, Hyejung Lee, Seungtae Kim
OBJECTIVE: To clarify the effects of acupuncture stimulation at Zusanli (ST 36) on the hormonal changes. METHODS: Eight-week-old male C57BL/6 mice received acupuncture stimulation at acupoint ST 36 or Quchi (LI 11) once a day for 3 or 5 days in the acupuncture-stimulated groups, but not received in the normal group (n =6 in each group). On day 3 or 5, animals were given 0.1 mL of charcoal orally with a bulbed steel needle, 30 min after the last acupuncture stimulation...
September 1, 2016: Chinese Journal of Integrative Medicine
Jing Lin, Qiao-Yan Cai, Wen Xu, Jiu-Mao Lin, Jun Peng
OBJECTIVE: To study the chemical composition, anticancer, anti-neuroinflflammatory, and antioxidant activities of the essential oil of Patrinia scabiosaefolia (EO-PS). METHODS: Patrinia scabiosaefolia was analyzed by gas chromatography-mass spectrometry. Eight human carcinoma cell lines, including SGC-7901, AGS, HepG2, HT-29, HCT-8, 5-FU/HCT-8, HeLa, and MDA-MB-231, were assessed by methylthiazolyldiphenyltetrazolium bromide (MTT) assay. Anti-neuroinflflammatory activity was assessed by production of interleukin (IL)-1β and IL-6 induced by lipopolysaccharide in BV-2 cells (microglia from mice)...
September 1, 2016: Chinese Journal of Integrative Medicine
Xu-Dong Tang, Bin Lu, Zhen-Hua Li, Wei Wei, Li-Na Meng, Bao-Shuang Li, Zhi-Peng Tang, Rui Gao, Feng-Yun Wang, Fang Lu, Li-Qun Bian, Ying-Pan Zhao, Ping Wang, Yin-Qiang Zhang
OBJECTIVE: To evaluate the efficacy and safety of Chinese medicine (CM) decoction Chang'an I Recipe (I) in the treatment of irritable bowel syndrome with diarrhea (IBS-D). METHOD: A multicenter, randomized, double-blind, placebo-controlled clinical trial was designed. Based on the order of inclusion, the IBS-D patients were randomly assigned to the treatment group or the placebo control group, administrated with Chang'an I Recipe or placebo, 150 mL/bag, 3 times daily, for 8 weeks...
August 3, 2016: Chinese Journal of Integrative Medicine
Chun-Hung Yang, Heng-Yuan Chang, Yi-Chuan Chen, Chia-Chen Lu, Shyh-Shyun Huang, Guan-Jhong Huang, Hsin-Chih Lai
OBJECTIVE: To study whether the ethanol extract of Phellinus merrillii (EPM) has chemopreventive potential against liver carcinogenesis. METHODS: Thirty male Spraque-Dawley rats were randomly divided into control group, EPM control group, hepatocarcinoma control group, low-dose EPM group and high-dose EPM group, 6 in each group. Using the Solt and Farber protocol in a rat model of hepatocarcinogenesis, the chemopreventive effect of EPM on diethylnitrosamine (DEN)-initiated, 2-acetylaminofluorene (2-AAF) and partial hepatectomy (PH)-promoted liver carcinogenesis in rats was evaluated...
August 2, 2016: Chinese Journal of Integrative Medicine
Jun-Jie Ma, Hui-Ping Liu
OBJECTIVE: To investigate the efficacy of Aidi Injection () on overexpression of P-glycoprotein (P-gp) induced by vinorelbine and cisplatin (NP) regimen in patients with non-small cell lung cancer (NSCLC), and study the difference between intravenous administration and targeting intratumor administration of Aidi Injection with thoracoscope. METHODS: Totally 150 patients with NSCLC were randomly assigned to the control group, the intravenous group and the intratumor group by the random envelope method, 50 cases in each group...
August 2, 2016: Chinese Journal of Integrative Medicine
Min Yao, Yue-Li Sun, Rong-Liang Dun, Tian-Ying Lan, Jin-Long Li, Hyo Jin Lee, Noriko Haraguchi, Yong-Jun Wang, Xue-Jun Cui
OBJECTIVE: To summarize and critically assess the efficacy of Eastern and Western manipulative therapies for the treatment of neck pain in adults. METHODS: A search of PubMed/MEDLINE, the Cochrane Central Register of Controlled Trials,, EMBASE, etc. from their inception date to January 2014 with Chinese, Japanese, and Korean databases. Two reviewers independently selected randomized controlled trials (RCTs) with negative control or blank control, extracted data and assessed methodological quality...
August 2, 2016: Chinese Journal of Integrative Medicine
Ju-Feng Xia, Yoshinori Inagaki, Jian-Feng Zhang, Ling Wang, Pei-Pei Song
Chinese medicine (CM) has been used in clinical treatment for thousands of years in China, Japan, Korea, and other countries. CM is at present attracting many attentions around the world for reproductive health care and disease prevention, including treatment of female infertility. This review focuses on the CM treatment for female infertility patients, and supplies a summary on the efficacy, safety, and mechanism of some Chinese herbal medicines, herbal medicine-derived active compounds, and acupuncture. A large number of researches have reported that CM could alleviate or even cure female infertility by regulating hormone, improving reproductive outcome of in vivo fertilization, affecting embryonic implantation, curing polycystic ovarian syndrome, endometriosis, pelvic inflammatory disease, relieving mental stress, and regulating immune system...
August 2, 2016: Chinese Journal of Integrative Medicine
Li-Fang Wang, Zhen-Ye Xu, Zhong-Qi Wang, Ming Zhang, Gui-Ying Yan, An-Ji Hou, Hai-Bin Deng, Ji Wu, Xiao-Zhen Zhao, Yi Xiang, Lei Yu
OBJECTIVE: To study the efficacy and safety of Shuanghuang Shengbai Granule (, SSG), a traditional Chinese herbal medicine, on myelosuppression of cancer patients caused by chemotherapy. METHODS: A total of 330 patients were randomly assigned to the treatment group (220 cases, analysed 209 cases) and the control group (110 cases, analysed 102 cases) with a 2:1 ratio by envelope method. The patients in the treatment group at the first day of chemotherapy started to take SSG for 14 days, while the patients in the control group took Leucogon Tablets...
August 2, 2016: Chinese Journal of Integrative Medicine
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