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Clinical Medicine & Research

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https://www.readbyqxmd.com/read/29042447/anisocoria-secondary-to-anticholinergic-mydriasis-from-homeopathic-similasan-pink-eye-relief-drops
#1
Lin Chen, Joseph C Yeung, Dennis R Anderson
A 70-year-old-woman developed anisocoria after applying homeopathic eye drops (Similasan Pink Eye Relief) to her left eye. Her pupil was dilated for two weeks and did not respond to light or near stimuli for one week. Both 0.1 % and 1% pilocarpine failed to constrict her left pupil, and magnetic resonance imaging of her brain did not reveal any abnormality. The eye drops she had used contain belladonna extracts, which have a natural atropine component. This case demonstrates the importance, when evaluating a patient presenting with anisocoria, of knowing the chemical ingredients of the homeopathic eye drops, which often are not listed...
October 17, 2017: Clinical Medicine & Research
https://www.readbyqxmd.com/read/29018005/the-clinical-presentation-of-subcutaneous-phaeohyphomycosis-a-case-series-from-yetebon-ethiopia
#2
Rachel B Kang, Devin C Simonson, Sarah E Stoner, William A Agger
Subcutaneous phaeohyphomycosis is a chronic fungal infection usually found on the lower extremity and feet of agricultural workers in the tropics. It can present with various skin manifestations, verrucous to nodular plaques, and is caused by multiple species of fungi. Laboratory confirmation requires skin samples for pathology and fungal cultures. Cure, often difficult in resource-poor countries, requires months of antifungal therapy. We describe the cases of 3 men from Ethiopia who were seen and are being treated by American doctors who traveled there on a medical mission...
October 10, 2017: Clinical Medicine & Research
https://www.readbyqxmd.com/read/29018004/mid-upper-arm-circumference-and-arm-to-height-ratio-to-identify-obesity-in-school-age-children
#3
Sanguansak Rerksuppaphol, Lakkana Rerksuppaphol
BACKGROUND: In resource-poor settings, anthropometric parameters are evaluated as potential alternatives to the body mass index (BMI) for detecting overweight and obesity in children. To this end, the mid-upper arm circumference (MUAC) and the mid-upper arm circumference to height ratio (AHtR) were evaluated as proxies to BMI in Thai school-age children. STUDY DESIGN: An observational, cross-sectional study was performed on school-aged children. PARTICIPANTS: Children in grades 1 through 6 at all public elementary schools in the Ongkharak district, Nakhon Nayok, Thailand during May and June 2013 were included...
October 10, 2017: Clinical Medicine & Research
https://www.readbyqxmd.com/read/28751467/recurrent-thrombosis-in-patients-with-antiphospholipid-syndrome-receiving-newer-oral-anticoagulants-a-case-report-and-review-of-literature
#4
Akanksha Joshi, Jason Hong, Chokkalingam Siva
We present the case of a patient with primary APS who had a recurrence of thrombotic event while on treatment with rivaroxaban and had to be restarted on warfarin. The current literature on recurrence of thrombotic events in patients with antiphospholipid syndrome (APS) treated with newer oral anticoagulants (NOAC) is also reviewed. Relevant case reports and case series were identified by searching the Medline database using the key words antiphospholipid syndrome, anticoagulants and names of the NOACs, and data on individual patients was abstracted...
June 2017: Clinical Medicine & Research
https://www.readbyqxmd.com/read/28751466/treatment-refractory-sternocostoclavicular-hyperostosis
#5
Ralph Yachoui, Mazen Kreidy, Brian J Parker
Sternocostoclavicular hyperostosis (SCCH) is an infrequent chronic inflammatory disorder of the axial skeleton of unknown origin. SCCH goes often unrecognized due to a low level of awareness for the disorder. It typically presents with relapsing and remitting pain in the shoulder, neck, and anterior chest wall area with occasional swelling and tenderness of the sternoclavicular area. The diagnosis is confirmed radiologically by sclerosis and hyperostosis of the sternoclavicular joints. There have been several reports in which intravenous bisphosphonates and tumor necrosis factor-inhibitors have shown reasonable efficacy in the treatment of this disorder...
June 2017: Clinical Medicine & Research
https://www.readbyqxmd.com/read/28487450/pulmonary-malt-lymphoma-in-patients-with-sj%C3%A3-gren-s-syndrome
#6
Ralph Yachoui, Chady Leon, Kajal Sitwala, Mazen Kreidy
To describe clinical features and outcomes of seven patients with pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma in the setting of underlying primary Sjögren's syndrome from a single center, we reviewed medical records of consecutive patients with pulmonary MALT lymphoma evaluated at our facility from January 1, 1999 to December 31, 2015 for clinical features, laboratory, pathologic and radiographic findings, management, and outcomes. Out of 13 patients with pulmonary MALT lymphoma, 7 (54 %) met the criteria for Sjögren's syndrome...
June 2017: Clinical Medicine & Research
https://www.readbyqxmd.com/read/28487449/voriconazole-induced-periostitis-deformans-a-mimicker-of-hypertrophic-pulmonary-osteoarthropathy
#7
Karim Ladak, Laurence Rubin
No abstract text is available yet for this article.
June 2017: Clinical Medicine & Research
https://www.readbyqxmd.com/read/28487448/incidence-of-primary-biliary-cholangitis-in-a-rural-midwestern-population
#8
Rajan Kanth, Ram Babu Shrestha, Indira Rai, Jeffrey J VanWormer, Praveen K Roy
BACKGROUND: Primary biliary cholangitis (PBC) is a rare disease with incidence that varies with time and geography. Only two studies have assessed PBC incidence in the United States, with the most recent appearing over a decade ago. The objective of the present study was to assess PBC incidence in the United States in a more recent era. METHODS: The incidence of PBC was assessed in a population-based cohort in rural, Midwestern Wisconsin over two decades spanning from June 1992 through June 2011...
June 2017: Clinical Medicine & Research
https://www.readbyqxmd.com/read/28373287/professor-monastyrski-n-d-1847-1888-one-of-the-forgotten-pioneers-of-biliary-surgery
#9
Mahir Gachabayov, Kubach Kubachev
Today, the ingenious and untimely deceased surgeon Monastyrski's name is almost lost in the history of medicine and means little, if anything, to young surgeons. Monastyrski Nestor Dmitrievich was born in 1847 in Czerniowce and graduated from the medical faculty of the University of Vienna. Deeply inspired by the stars of European medicine and surgery: Billroth, Kaposi, Mikulicz, he became a brilliant surgeon and teacher. Monastyrski performed the first gastroenterostomy in Russia and was one of the pioneers of the aseptic method in Russia...
June 2017: Clinical Medicine & Research
https://www.readbyqxmd.com/read/28373286/statistical-application-and-cost-saving-in-a-dental-survey
#10
Po-Huang Chyou, Dixie Schroeder, Kelsey Schwei, Amit Acharya
OBJECTIVE: To effectively achieve a robust survey response rate in a timely manner, an alternative approach to survey distribution, informed by statistical modeling, was applied to efficiently and cost-effectively achieve the targeted rate of return. DESIGN: A prospective environmental scan surveying adoption of health information technology utilization within their practices was undertaken in a national pool of dental professionals (N=8000) using an alternative method of sampling...
June 2017: Clinical Medicine & Research
https://www.readbyqxmd.com/read/28373288/status-update-on-translation-of-integrated-primary-dental-medical-care-delivery-for-management-of-diabetic-patients
#11
Ingrid Glurich, Gregory Nycz, Amit Acharya
Escalating prevalence of both diabetes and periodontal disease, two diseases associated with bidirectional exacerbation, has been reported. Periodontal disease represents a modifiable risk factor that may reduce diabetes onset or progression, and integrated models of cross-disciplinary care are needed to establish and manage glycemic control in affected patients. An ad-hoc environmental scan of current literature and media sought to characterize factors impacting status of integrated care models based on review of the existing evidence base in literature and media surrounding: 1) current cross-disciplinary practice patterns, 2) epidemiological updates, 3) status on risk assessment and screening for dysglycemia in the dental setting, 4) status on implementation of quality metrics for oral health, 5) care model pilots, and 6) public health perspectives...
April 3, 2017: Clinical Medicine & Research
https://www.readbyqxmd.com/read/28188140/angioimmunoblastic-t-cell-lymphoma-with-polyarthritis-resembling-rheumatoid-arthritis
#12
Ralph Yachoui, Nouman Farooq, Jonathan V Amos, Gene R Shaw
Angioimmunoblastic T-cell lymphoma (AITL) is a rare subtype of peripheral T-cell lymphoma (PTCL). AITL typically presents with lymphadenopathy, fever, rash, hepatosplenomegaly, and rarely polyarthritis. We report the case of a 50-year-old female who presented with lymphadenopathy, rash, and symmetric polyarthritis. She was later diagnosed with AITL and was treated with chemotherapy with resolution of arthritis. AITL should be suspected in paitents presenting with rheumatoid-like arthritis and diffuse lymphadenopathy...
December 2016: Clinical Medicine & Research
https://www.readbyqxmd.com/read/28188139/exploring-gender-difference-in-sleep-quality-of-young-adults-findings-from-a-large-population-study
#13
Yaqoot Fatima, Suhail A R Doi, Jake M Najman, Abdullah Al Mamun
OBJECTIVES: To explore if gender difference in sleep quality is due to higher prevalence of depression in females, and whether socio-demographic and lifestyle factors have a differential effect on sleep quality in males and females. METHODS: Youth self-reports and the Pittsburgh Sleep Quality Index were used to assess sleep quality and associated risk factors. Logistic regression analyses were used to analyze the association between various risk factors and poor sleep quality...
December 2016: Clinical Medicine & Research
https://www.readbyqxmd.com/read/27777245/subacute-sclerosing-panencephalitis-in-a-child-with-human-immunodeficiency-virus-co-infection
#14
Pradeep Kumar Maurya, Mayur Deepak Thakkar, Dinkar Kulshreshtha, Ajai Kumar Singh, Anup Kumar Thacker
Subacute sclerosing panencephalitis is a fatal infectious disease of childhood caused by persistence of the measles virus in the brain. The effect of human immunodeficiency virus (HIV) co-infection on subacute sclerosing panencephalitis remains elusive and rare. We report a child who developed subacute sclerosing panencephalitis following a short latency period and a rapidly progressive course with HIV co-infection.
December 2016: Clinical Medicine & Research
https://www.readbyqxmd.com/read/27630187/dietary-nitrate-acutely-and-markedly-increased-exhaled-nitric-oxide-in-a-cystic-fibrosis-case
#15
Conor P Kerley, Emma Kilbride, Peter Greally, Basil Elnazir
Airway nitric oxide (NO) is a ubiquitous signaling molecule with bronchoprotective, anti-inflammatory and anti-infective roles. Cystic fibrosis (CF) is a chronic lung condition associated with deceased exhaled NO. Strategies to increase exhaled NO in CF have yielded inconsistent results. A potential new method of increasing systemic NO involves ingestion of dietary, inorganic nitrate which is reduced to nitrite and NO. We present the case of a 12-year-old, athletic boy with CF who demonstrated acute but marked increases in exhaled NO following dietary nitrate consumption compared to placebo...
December 2016: Clinical Medicine & Research
https://www.readbyqxmd.com/read/27573534/immune-mediated-necrotizing-myopathy-a-cause-of-isolated-myopathy-of-neck-extensor-muscle
#16
Rahul Sehgal, Rafael Medina-Flores, Ralph Yachoui, Charles V Kenney
Immune mediated necrotizing myopathy (IMNM) is a unique form of myositis that is characterized by distinct muscle biopsy features including abundant myofiber necrosis, degeneration, and regeneration with only minimal, if any, inflammation on muscle biopsy. IMNM is clinically similar to idiopathic inflammatory myopathy (IIM); hence, muscle biopsy is essential to diagnose IMNM. Herein we describe a case of neck extensor weakness due to necrotizing myopathy. Isolated weakness of the neck extensor muscles is uncommon in IIM and IMNM...
December 2016: Clinical Medicine & Research
https://www.readbyqxmd.com/read/27565514/developing-research-priorities-for-prediction-and-prevention-of-preterm-birth
#17
William A Agger, Charles W Schauberger, James K Burmester, Sanjay K Shukla
No abstract text is available yet for this article.
December 2016: Clinical Medicine & Research
https://www.readbyqxmd.com/read/27503793/adverse-childhood-experiences-and-health-in-adulthood-in-a-rural-population-based-sample
#18
Kristen C Iniguez, Rachel V Stankowski
BACKGROUND: Adverse childhood experiences (ACEs), including emotional abuse, substance abuse in the household, separation or divorce, physical abuse, violence between adults, mental illness in the household, sexual abuse, or incarceration of a household member, have the potential to profoundly impact health and well-being in adulthood. To assess whether previously reported relationships between ACEs and health outcomes withstand validation, we conducted a community-based ACE study with the unique capacity to link self-reported ACEs and other survey results to validated health data in an electronic medical record (EMR)...
December 2016: Clinical Medicine & Research
https://www.readbyqxmd.com/read/27401794/bowel-in-chest-type-iv-hiatal-hernia
#19
William Krause, Jennifer Roberts, Romel J Garcia-Montilla
No abstract text is available yet for this article.
June 2016: Clinical Medicine & Research
https://www.readbyqxmd.com/read/27256549/urological-procedures-in-urolithiasis-and-their-association-with-chronic-kidney-disease
#20
Matthew D'Costa, Radmila Savcic-Kos, Jingbo Huang, Andrew D Rule, Narayana Murali
BACKGROUND AND OBJECTIVES: Epidemiological evidence suggests that patients with urolithiasis are at increased risk for end-stage renal disease (ESRD). It is unclear if urological intervention impacts the progression of chronic kidney disease (CKD). METHODS: We conducted a retrospective observational cohort study of patients in the Marshfield Epidemiologic Study Area database between January 1991 and May 2007, where 1,340 patients diagnosed with urolithiasis were extracted...
June 2016: Clinical Medicine & Research
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