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Journal of the Chinese Medical Association: JCMA

Ching-Wei Lee, Shih-Hsien Sung, Yi-Lin Tsai, Ting-Yung Chang, Chiao-Po Hsu, Chih-Cherng Lu, Chun-Che Shih
BACKGROUND: The transcatheter edge-to-edge mitral valve repair, using MitraClip, has been a safe and effective treatment for severe mitral regurgitation (SMR) in the westerners. However, the therapeutic results of the MitralClip in Taiwan remained elucidated. METHODS: Patients with symptomatic SMR were evaluated by the heart team. For those with high or prohibitive surgical risks, transcatheter mitral valve repair was performed in hybrid operation room. During procedure, continuous hemodynamic monitoring was conducted...
December 29, 2017: Journal of the Chinese Medical Association: JCMA
Yasuhiro Otaki, Makiko Ishida DaSilva, Yuichi Saito, Yasuaki Oyama, Giichiro Oiso, Tomohiko Yoshida, Masakazu Fukuhara, Mitsuru Moriyama
BACKGROUND: Septic arthritis (SA) cases can result in claims or litigation because of poor prognosis even if it is unavoidable. Although these claims or litigation are useful for understanding causes and background factors of medical errors, the characteristics of malpractice claims associated with SA remain undetermined in Japan. This study aimed to increase our understanding of malpractice claims in the clinical management of SA. METHODS: We analyzed 6 civil precedents and 16 closed claims of SA from 8530 malpractice claims processed between July 2004 and June 2014 by the Tokyo office of Sompo Japan Nipponkoa Insurance, Incorporated...
December 28, 2017: Journal of the Chinese Medical Association: JCMA
Li-Tzu Lee, Yong-Kie Wong, Chan Man-Yee, Kuo-Wei Chang, Shyh-Chang Chen, Chiou-Tuz Chang, John Wang
BACKGROUND: The prognostic predict biomarkers are important in oral squamous cell carcinoma (OSCC). We investigated the expression patterns and quantitation of hypoxia-inducible factor-1 alpha (HIF-1α) and vascular endothelial growth factor (VEGF) in OSCC patients. Among OSCC patients with recurrence and metastasis, the expression percentages of HIF-1α and VEGF also were analyzed. METHODS: Thirty-eight patients (8 hyperkeratosis, 30 oral squamous cell carcinoma) were included in this study...
December 27, 2017: Journal of the Chinese Medical Association: JCMA
Hwa-Yen Chiu, Liang-Yu Lin, Wen-Chi Chou, Wen-Liang Fang, Yi-Ming Shyr, Yi-Chen Yeh, Peter Mu-Hsin Chang, Ming-Han Chen, Yi-Ping Hung, Yee Chao, Sheng-Hsuan Chien, Ming-Huang Chen
BACKGROUND: Currently, the role of dacarbazine (DTIC) based chemotherapy in neuroendocrine tumors (NETs) in Asia is unclear. Here, we report the outcomes of dacarbazine (DTIC)-based chemotherapy in Taiwan population. METHODS: DTIC alone (250 mg/m2/day), or 5-fluorouracil (5-FU, 500 mg/m2/day) and DTIC (200 mg/m2/day) with or without epirubicin (200 mg/m2/day), for 3 days, every 3-4 weeks. Subgroups were analyzed by grading, and by Ki-67 index. RESULTS: 48 patients were reviewed in this study, including 3 had grade 1 tumors, 23 had grade 2, while 22 were grade 3...
December 26, 2017: Journal of the Chinese Medical Association: JCMA
Chih-Chieh Tseng, Ming-Tang Lai, Chia-Che Wu, Sheng-Po Yuan, Yi-Fang Ding
BACKGROUND: Health care systems and physicians need to conform to budgets and streamline resources to provide cost-effective quality care. Although endoscopic tympanoplasty (ET) has been performed for decades, no studies on the cost-effectiveness of ET and microscopic tympanoplasty (MT) for treating chronic otitis media have been published. The present study aimed to compare the cost-effectiveness of ET and MT for treating chronic otitis media. METHODS: This study was performed using a Cohort-style Markov decision-tree economic model with a 30-year time horizon...
December 26, 2017: Journal of the Chinese Medical Association: JCMA
Huey-Ling You, Chao-Chun Huang, Chung-Jen Chen, Cheng-Chin Chang, Pei-Lin Liao, Sheng-Teng Huang
BACKGROUND: The pandemic influenza A (H1N1) virus has spread worldwide and infected a large proportion of the human population. Discovery of new and effective drugs for the treatment of influenza is a crucial issue for the global medical community. According to our previous study, TSL-1, a fraction of the aqueous extract from the tender leaf of Toonasinensis, has demonstrated antiviral activities against pandemic influenza A (H1N1) through the down-regulation of adhesion molecules and chemokine to prevent viral attachment...
December 26, 2017: Journal of the Chinese Medical Association: JCMA
Chun-Chieh Chao, Yi-Chun Chen, Chun-Ming Shih, Sen-Kuang Hou, Raghu R Seethala, Imoigele P Aisiku, Chuan-Chin Huang, Peter C Hou, Wei-Fong Kao
BACKGROUND: This retrospective study evaluated the use of a smartphone application to facilitate communication between the emergency physician (EP) and the interventional cardiologist in order to minimize the time to cardiac catheterization laboratory (CCL) activation and time to percutaneous coronary intervention (PCI). METHODS: We retrospectively collected pertinent time-points in the management of patients diagnosed with STEMI in the emergency department and their outcome...
December 26, 2017: Journal of the Chinese Medical Association: JCMA
Mi Hye Kim, Haesu Lee, You Yeon Choi, Dae Hoon Lee, Woong Mo Yang
BACKGROUND: Scutellaria baicalensis (SB) is widely used as a medicinal plant to treat various inflammatory diseases. In the present study, we investigated the effects of SB on periodontitis in ligature-induced experimental rat model. METHODS: Rats were subjected to a ligature placement around the first molar of the mandible to induce periodontitis. 100 mg/kg SB extracts were orally administered for 14 days. The molar tissues were stained with 1% methylene blue...
December 26, 2017: Journal of the Chinese Medical Association: JCMA
Carla Lobina, Giancarlo Colombo, Gian Luigi Gessa, Mauro A M Carai, Pietro Allegrini, Paolo Morazzoni, Antonella Riva
BACKGROUND: Preparations from roots of Salvia miltiorrhiza, a herb widely used in traditional Chinese medicine, have been reported to induce a series of central effects, including sedation. In the wake of this ethnopharmacological information, the present study was designed to assess the anxiolytic potential of an extract of S.miltiorrhiza roots. METHODS: To this end, rats were acutely treated with S.miltiorrhiza extract (0, 50, and 100 mg/kg; i.g.) and exposed to the Elevated Plus Maze (EPM) test...
December 26, 2017: Journal of the Chinese Medical Association: JCMA
Taner Turan, Gunsu Kimyon Comert, Osman Turkmen, Isin Ureyen, Erdem Fadiloglu, Alper Karalok, Tolga Tasci, Gokhan Tulunay, Derman Basaran
BACKGROUND: To determine the efficacy of lymphadenectomy and adjuvant radiotherapy in patients with endometrioid-type cancer confined to the uterine corpus. METHODS: A total of 323 patients were evaluated. Patients were stratified according to depth of myometrial invasion (DMI) and tumor grade. RESULTS: Lymphadenectomy was performed in 83% of the entire cohort. Age (<60 vs. ≥60) and DMI affected disease-free survival. Addition of lymphadenectomy improved the disease-specific survival...
December 26, 2017: Journal of the Chinese Medical Association: JCMA
Bingqian Zhu, Meng Xie, Chang G Park, Mary C Kapella
BACKGROUND: Sleep disturbance is a major health issue in people with type 2 diabetes (T2DM). The Pittsburgh Sleep Quality Index (PSQI) has been the most widely used instrument to measure subjective sleep disturbance. Nevertheless, its factor structure in the context of T2DM has not been examined. The purpose of the study is to evaluate the factor structure of the PSQI in Chinese adults with T2DM and thereby to facilitate its use in clinical practice and research. METHODS: The PSQI (Chinese version) was administered to 240 patients with T2DM...
December 16, 2017: Journal of the Chinese Medical Association: JCMA
Chia-Ying Tseng, Julia Chia-Yu Chang, Yen-Chia Chen, Hsien-Hao Huang, Chien-Sheng Lin, Chorng-Kuang How, David Hung-Tsang Yen
BACKGROUND: Indexes of heart rate variability (HRV) appear to reflect severity and may have prognostic value in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). We hypothesized that AECOPD without adequate treatment response would demonstrate impaired cardiac autonomic regulation and changes in HRV after emergency department (ED) treatment. METHODS: A prospective study of measuring HRV in admitted and discharged patients with AECOPD shortly after ED arrival and again 24 h after treatment...
December 15, 2017: Journal of the Chinese Medical Association: JCMA
Yishu Tang, Wenbo Ma, Chunxia Zhou, Dongmei Wang, Shuren Zhang
BACKGROUND: Tumor-induced immunosuppression can impede tumor-specific immune responses and limit the effects of cancer immunotherapy. The aim of this study was to investigate the possible effects of sequential chemoimmunotherapeutic strategies to enhance antitumor immune responses. METHODS: Using the E7-expressing tumor TC-1 as the tumor model, the treatment groups were divided into the following groups: (1) inactivated allogeneic leukocyte infusion (ALI), (2) ALI + MMC-inactivated TC-1 cell vaccine, and (3) ALI + MMC-inactivated TC-1 cell vaccine + cyclophosphamide (CTX)...
December 12, 2017: Journal of the Chinese Medical Association: JCMA
Hsu-Dong Sun, Huann-Cheng Horng, Chia-Hao Liu, Sheng-Mou Hsiao, Yi-Jen Chen, Wen-Hsun Chang, Peng-Hui Wang
BACKGROUND: To compare the short-term outcome of patients undergoing single-port laparoscopic salpingectomy (SP-LS) and conventional three-port laparoscopic salpingectomy (C-LS). METHODS: A retrospective evaluation of 112 patients with tubal pregnancies treated by one surgeon at a single teaching hospital. Among these, 47 patients were treated with SP-LS and the remaining 65 were treated with C-LS. RESULTS: The characteristics of patients were similar in both groups...
December 7, 2017: Journal of the Chinese Medical Association: JCMA
Sung-Lang Chen
No abstract text is available yet for this article.
December 6, 2017: Journal of the Chinese Medical Association: JCMA
Wei-Ming Cheng, Yu-Hua Fan, Alex T L Lin
BACKGROUND: The aim of the study was to identify the impact of non-bladder co-morbid conditions on the urodynamic characteristics of patients with bladder pain syndrome/interstitial cystitis. METHODS: Patients with bladder pain syndrome/interstitial cystitis completed the screening questionnaires for chronic fatigue syndrome, irritable bowel syndrome, fibromyalgia, temporo-mandibular disorders, multiple chemical sensitivities, tension/migraine headache, and localized myofascial pain disorder...
December 6, 2017: Journal of the Chinese Medical Association: JCMA
Pei-Hsin Lin
BACKGROUND: Hemiplegic shoulder pain is common in stroke patients and can influence rehabilitation outcome. The underlying pathology can be various: in addition to impaired motor control and altered peripheral and central nervous activity, soft tissue lesions may also play an important role. It remains unclear how these pathologies may interact or correlate with each other. METHODS: This retrospective study collected data from 26 stroke patients who received sonography examination due to shoulder pain...
December 4, 2017: Journal of the Chinese Medical Association: JCMA
Chia-Yen Dai, Ching-Yeh Lin, Pei-Chien Tsai, Ping-Yi Lin, Ming-Lun Yeh, Chung-Feng Huang, Wen-Tsan Chang, Jee-Fu Huang, Ming-Lung Yu, Yao-Li Chen
BACKGROUND: Health burdens of hepatocellular carcinoma (HCC) are emerging quickly in the world, including in Taiwan. Surgical resection has been recognized as the first-line treatment for early tumors. This study aimed to investigate the prognostic risk factors for mortality and recurrence rate in Taiwan, which has a high prevalence of chronic viral hepatitis. METHODS: A total of 397 HCC patients receiving tumor resection were consecutively examined in central Taiwan from 2008 to 2014...
December 4, 2017: Journal of the Chinese Medical Association: JCMA
Fa-Kung Lee, Huann-Cheng Horng, Peng-Hui Wang
No abstract text is available yet for this article.
December 4, 2017: Journal of the Chinese Medical Association: JCMA
Yan Sun, Jin-Guo Liu, Yong-Chun Zheng, Chun-Ling Xiao, Bing Wan, Li Guo, Xu-Guang Wang, Wei Bo
BACKGROUND: The steps to the moon never stopped after the Apollo Project. Lessons from manned landings on the moon have shown that lunar dust has great influence on the health of astronauts. In this paper, comparative studies between the lunar soil simulant (LSS) and PM2.5 were performed to discover their harm to human biological systems and explore the methods of prevention and treatment of dust poisoning for future lunar manned landings. METHODS: Rats were randomly divided into the control group, two CAS-1 lunar soil simulant groups (tracheal perfusion with 7 mg and 0...
November 30, 2017: Journal of the Chinese Medical Association: JCMA
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