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Journal of the Chinese Medical Association: JCMA

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https://www.readbyqxmd.com/read/30145058/evaluation-of-peripheral-blood-nk-cell-subsets-and-cytokines-in-unexplained-recurrent-miscarriage
#1
Hajar Adib Rad, Zahra Basirat, Amrollah Mostafazadeh, Mahbobeh Faramarzi, Ali Bijani, Hamid Reza Nouri, Shima Soleimani Amiri
BACKGROUND: Recurrent miscarriage is considered as one of the main problems in women's reproductive health. The aim of the present study was to evaluate the natural killer cells (NK cells) and cytokines in unexplained recurrent miscarriage and fertile women. METHODS: In this case-control study, 40 women with unexplained recurrent miscarriage were assigned to the case group and 40 fertile women were assigned to the control group. NK cell subsets (CD56+ CD16+ /CD56+ CD16- ) and cytokines (IL-2/IL-12) levels in the peripheral blood (PB) were used for assessing immunologic problems...
December 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30143430/correlations-between-serum-hepatitis-b-surface-antigen-and-hepatitis-b-core-antibody-titers-and-liver-fibrosis-in-treatment-na%C3%A3-ve-chb-patients
#2
Min-Ran Li, Huan-Wei Zheng, Shun-Mao Ma, Yun-Yan Liu, Lan-Xia Qie, Jun-Qing Li, De-Hua Wang, Xing-Li Sun, Gui-Fang Ren, Yan-Hua Zheng, Yu-Ling Wang, Er-Hei Dai
BACKGROUND: Previous studies have revealed that quantitative hepatitis B surface antigen (HBsAg) or hepatitis B core antibody (qAnti-HBc) levels can be used as predictors of treatment response in both interferon-α and nucleoside analogue therapies. Few data have been published regarding the relationship between quantitative HBsAg or Anti-HBc levels and liver fibrosis stages in patients with chronic hepatitis B (CHB). METHODS: We conducted a cross-sectional study of treatment-naïve CHB patients...
December 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30131295/patient-response-prediction-with-logistic-regression-in-gastrointestinal-endoscopy-under-midazolam-alfentanil-sedation-performed-as-well-as-response-surface-model
#3
Mei-Yung Tsou, Jing-Yang Liou, Chien-Kun Ting, Shih-Pin Lin
BACKGROUND: Researchers have used logistic regression (LR) and non-linear response surface models (RSMs) to predict patient responses to sedation. The reduced Greco and hierarchy RSMs have proven to be more appropriate than other RSMs in gastrointestinal endoscopies using midazolam and alfentanil. In this study, we evaluate the performance of a simpler model, LR, and compared it with that of RSM. METHODS: Thirty-three patients who received esophagogastroduodenoscopy (EGD) and colonoscopy sedation with midazolam and alfentanil were enrolled in the study...
December 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30100355/comparison-of-cancer-detection-between-18-and-12-core-prostate-biopsy-in-asian-patients-with-prostate-specific-antigen-levels-of-4-20-ng-ml
#4
Bo-Ren Wang, Cheng Che Chen, Ren-Hao Zheng, Ju-Chuan Hu, Yen-Chuan Ou
BACKGROUND: Although prostate biopsy is an accepted option for cancer detection, there is little data regarding the clinical outcome of 18-core transrectal ultrasound (TRUS)-guided biopsy. This retrospective study compared cancer detection rates and biopsy complications between 12- and 18-core TRUS biopsy in Asian patients with prostate-specific antigen (PSA) levels between 4.0 and 20.0 ng/mL. METHODS: In total, 1120 consecutive patients with PSA levels between 4...
December 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30100353/early-achievement-of-full-donor-chimerism-after-allogeneic-hematopoietic-stem-cell-transplantation-predicts-lower-relapse-risk-in-patients-with-acute-lymphoblastic-leukemia
#5
Chien-Ting Chen, Jyh-Pyng Gau, Jing-Hwang Liu, Tzeon-Jye Chiou, Liang-Tsai Hsiao, Yao-Chung Liu
BACKGROUND: Acute lymphoblastic leukemia (ALL) remains one of the most difficult-to-cure hematological malignancies. Allogeneic hematopoietic stem cell transplantation (HSCT) provides curative potential but a substantial proportion of patients eventually will relapse. It is unknown if there are any modifiable factors exists that could improve survival or predict relapse immediately after HSCT is unknown. The aim of this study was to explore whether achieving early (<30 days) full donor chimerism (FDC) could predict disease relapse after allogeneic HSCT in ALL patients...
December 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30100351/hyperglycemia-crisis-in-head-and-neck-cancer-patients-with-platinum-based-chemotherapy
#6
Chien-Yu Huang, Yaoh-Shiang Lin, Yu-Hsi Liu, Sheng-Chiao Lin, Bor-Hwang Kang
BACKGROUND: The development of a hyperglycemic crisis in platinum-based chemotherapy-treated head and neck cancer patients, such as hyperosmolar hyperglycemic state (HHS), has been reported. Hyperglycemic crises are associated with a high risk of comorbidity and may delay cancer treatment if not promptly managed. METHODS: This is a retrospective study using cancer registry data from a tertiary medical center. Head and neck cancer patients who had been treated with platinum-based chemotherapy from January 2014 to December 2015 were enrolled for review...
December 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30031694/involvement-of-s100a4-mts1-and-associated-proteins-in-the-protective-effect-of-fluoxetine-against-mct-induced-pulmonary-hypertension-in-rats
#7
Zhan-Hong Song, Han-Ming Wang, Ming Liu, Yang Bai, Yun Wang, Huai-Liang Wang
BACKGROUND: Pulmonary arterial hypertension (PAH) is a complex pulmonary vasculature disease characterized by remodeling of the pulmonary vessels and a persistent increase in the pulmonary vascular resistance (PVR) with a poor prognosis. Serotonin increases the expression of S100A4/Mts1, which in turn stimulates the proliferation and migration of human pulmonary artery smooth muscle cells through the interaction with RAGE (receptor for advanced glycation end products) and thus S100A4/Mts1 has been implicated in the development of PAH in vitro...
December 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30017809/characterization-and-management-of-various-renal-cystic-lesions-by-sonographic-features
#8
REVIEW
Shee-Yen Tay, Chui-Mei Tiu, Bing Hu, Hsin-Kai Wang, Hong-Jen Chiou, Yung-Hui Lin, Yi-Chen Lai, Wing P Chan, Yi-Hong Chou
Renal cysts are common incidental findings in clinical practice. Most renal cysts detected in medical imaging are benign simple cysts. However, some are complicated by hemorrhage or infection or are associated with calcification. In these instances, difficulties can be encountered distinguishing the complicated cysts from cystic renal tumors such as cystic renal cell carcinoma, multilocular cystic nephroma, and mixed epithelial and stromal tumors. The Bosniak classification is widely used to categorize cystic renal lesions but is used to classify those discovered via computed tomography...
December 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29778549/linked-color-imaging-can-help-gastric-helicobacter-pylori-infection-diagnosis-during-endoscopy
#9
Tsung-Hsing Chen, Chen-Ming Hsu, Hao-Tsai Cheng, Yin-Yi Chu, Ming-Yao Su, Jun-Te Hsu, Ta-Sen Yeh, Chang-Fu Kuo, Cheng-Tang Chiu
BACKGROUND: Esophagogastroduodenoscopy (EGD) is a standard tool for detection of mucosal and submucosal lesions. However, identification of Helicobacter pylori (H. P) infection using EGD alone is limited in accuracy. Linked color imaging (LCI) is a novel tool to capture real-time image with sufficient contrast to observe mucosal microstructure. METHODS: This study aims to evaluate the applicability of LCI in the identification of H. pylori infection. Consecutive 122 patients scheduled for EGD were included...
December 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29778548/risk-factors-of-the-peptic-ulcer-bleeding-in-aging-uremia-patients-under-regular-hemodialysis
#10
Xi-Hsuan Lin, Chung-Chi Lin, Yuan-Jen Wang, Jiing-Chyuan Luo, Shih-Hao Young, Ping-Hsien Chen, Ming-Chih Hou, Fa-Yauh Lee
BACKGROUND: Previous studies have shown that uremia patients under hemodialysis (HD) have a significantly higher occurrence of peptic ulcer bleeding (PUB) than healthy controls and that elderly patients remain at high risk of peptic ulcer disease (PUD) and PUB. Here we aimed to identify the risk factors for PUB in aging (≥65-years-old) uremic patients under regular HD. METHODS: Using data from the National Health Insurance Research Database of Taiwan, we compared 18,252 aging regular HD patients and 17,883 age-, gender-, and medication-matched patients without kidney disease (control group)...
December 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30369404/accuracy-of-implant-placement-with-a-computer-aided-fabricated-surgical-template-with-guided-parallel-pins-a-pilot-study
#11
Rai-Jei Chang, Hui-Ling Chen, Liang-Gie Huang, Yong-Kie Wong
BACKGROUND: A precise positioning for dental implant placement is important for further prosthesis fabrication and maintenance. Computer-aided surgery has been developed to transfer digitally planned implant positioning to the patient over the past decades. This study aimed to evaluate the accuracy of a computer-aided laboratory-fabricated surgical template. A further objective was to compare the accuracy between in vivo and in vitro groups. METHODS: A total of 20 implants were placed in the posterior tooth region through the aid of surgical templates on 17 partially edentulous patients in the in vivo group...
November 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30366589/assisted-reproductive-technology-and-adverse-pregnancy-outcome-focus-on-maternal-death
#12
EDITORIAL
Fa-Kung Lee, Huann-Cheng Horng, Peng-Hui Wang
No abstract text is available yet for this article.
November 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30228078/impact-of-hypoxic-and-mesopic-environments-on-visual-acuity-contrast-sensitivity-and-accommodation-in-subjects-with-lasik-surgery-and-aircrew-candidate
#13
Hsin-Ting Lin, Hui-Ju Chan, Cheng-Wen Ho, Ming-Cheng Tai, Jiann-Torng Chen, Chang-Min Liang
BACKGROUND: The safety of Laser-assisted in situ keratomileusis (LASIK) in aircrew was unclear, in addition, LASIK was not yet approved for aircrew of Taiwan Air Force. This study was aimed to evaluate visual performance in LASIK eyes in hypoxic and twilight environment. METHODS: 48 myopic eyes of 24 subjects enrolled in this study were divided into LASIK group and control group. Subjects were exposed in hypoxic (15% O2 ) and mesopic (3 cd/m2 ) environment. Visual performance was evaluated using the Early Treatment of Diabetic Retinopathy Study (ETDRS) visual chart, and Functional Acuity Contrast Test (FACT) before and after the expirement...
November 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30201190/reply
#14
LETTER
Nafiye Yılmaz, Banu Seven, Hakan Timur, Ayçağ Yorgancı, Hasan Ali İnal, Müberra Namlı Kalem, Ziya Kalem, Özge Han, Banu Bilezikçi
No abstract text is available yet for this article.
November 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30201186/fertility-enhancing-agents
#15
LETTER
Fa-Kung Lee, Peng-Hui Wang
No abstract text is available yet for this article.
November 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30197114/impact-of-code-stroke-on-thrombolytic-therapy-in-patients-with-acute-ischemic-stroke-at-a-secondary-referral-hospital-in-taiwan
#16
Cheng-Lun Hsiao, Yu-Chin Su, Fu-Yi Yang, Chih-Yang Liu, Han-Lin Chiang, Guei-Chiuan Chen, Po-Jen Hsu, Pei-Ya Chen, Shinn-Kuang Lin
BACKGROUND: Efficacy of thrombolytic therapy decreases with time elapsed from symptom onset. We sought to identify the impact of code stroke on the thrombolytic therapy. METHODS: Code stroke is activated by the emergency physician when a patient is eligible for thrombolytic therapy. We retrospectively reviewed patients with acute ischemic stroke between January 2011 and December 2014. RESULTS: In total, 1809 patients were enrolled. Code stroke was activated in 233 of 351 patients arriving at the emergency room (ER) within 3 h of symptom onset, and in 21 patients arriving >3 h...
November 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30177489/situation-of-seven-day-service-among-family-medicine-clinics-in-taiwan-a-nationwide-survey
#17
Wei-Ting Chang, Yi-Jen Wang, Hsin-I Leu, Tzeng-Ji Chen, Shinn-Jang Hwang, Li-Fang Chou, Ming-Hwai Lin
BACKGROUND: General medicine practices in England are required to provide services from 8am to 8pm on weekdays and to also open on Saturdays and Sundays. Internationally, however, the literature regarding the temporal availability of primary health care on national levels is scarce. METHODS: To provide such information regarding Taiwan, in this study, all family medicine clinics within Taiwan's National Health Insurance system were stratified by urbanization level, and the opening hours of the clinics were then analyzed...
November 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30146457/evaluating-cerebral-hemodynamics-using-quantitative-digital-subtraction-angiography-and-flat-detector-computed-tomography-perfusion-imaging-a-comparative-study-in-patients-with-carotid-stenosis
#18
Liang-Wei Chen, Chung-Jung Lin, Wan-Yuo Guo, Sheng-Che Hung, Han-Jui Lee, Ko-Kung Chen, Feng-Chi Chang, Chao-Bao Luo, Wei-Fa Chu
BACKGROUND: The efficacy of both quantitative digital subtraction angiography (QDSA) and flat-detector computed tomography perfusion (FD-CTP) is equivalent to that of magnetic resonance perfusion (MRP) in assessing perfusion deficits in carotid stenosis. This study evaluated the feasibility of using FD-CTP to monitor cerebral hemodynamics during carotid stenting. METHODS: Thirteen patients with extracranial carotid stenosis (>70%) were included. Both QDSA and two FD-CTP sessions were performed before and after carotid stenting...
November 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30139671/baicalein-attenuates-neuropathic-pain-and-improves-sciatic-nerve-function-recovery-in-rats-with-partial-sciatic-nerve-transection
#19
Hou-Chuan Lai, Chueng-He Lu, Chih-Shung Wong, Bo-Feng Lin, Shun-Ming Chan, Chan-Yang Kuo, Zhi-Fu Wu
BACKGROUND: Modulating the inflammatory response to nerve injury may provide therapeutic opportunities by aborting the neurobiological alterations that support the development of persistent pain. Baicalein, a 12-lipoxygenase inhibitor, has anti-inflammation properties. It also demonstrates anti-inflammatory functions by inhibiting lipopolysaccharide-induced barrier disruption, expression of cell adhesion molecules, and adhesion and migration of leukocytes. The aim of the present study was to assess the possibility of early treatment of neuropathic pain via the systemic injection of baicalein in rats with left partial sciatic nerve transection (PST)...
November 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/30131296/the-effect-of-inhaled-salbutamol-on-the-outcomes-of-transient-tachypnea-of-the-newborn
#20
Arash Malakian, Masoud Dehdashtian, Mohammad Raza Aramesh, Mohammad Hassan Aletayeb, Solmaz Heidari
BACKGROUND: Transient tachypnea of the newborn (TTN) is a self-limiting disease that results from a reduction in the rate of lung fluid clearance in neonates. A delay in lung fluid absorption in neonates disrupts the transition from intrauterine to extrauterine life. Use of beta-adrenergic antagonists, such as salbutamol, accelerates lung fluid clearance. The current study aimed to evaluate the effect of inhaled salbutamol on the clinical progression of TTN treatment. METHODS: In the current triple-blind clinical trial, a total of 148 inpatients diagnosed with TTN were randomly divided into 2 groups...
November 2018: Journal of the Chinese Medical Association: JCMA
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