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Cancer Imaging: the Official Publication of the International Cancer Imaging Society

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https://www.readbyqxmd.com/read/27927229/evaluation-of-tumor-recurrences-after-radical-prostatectomy-using-18f-choline-pet-ct-and-3t-multiparametric-mri-without-endorectal-coil-a-single-center-experience
#1
Felipe Couñago, Manuel Recio, Antonio Maldonado, Elia Del Cerro, Ana Aurora Díaz-Gavela, Israel J Thuissard, David Sanz-Rosa, Francisco José Marcos, Karmele Olaciregui, María Mateo, Laura Cerezo
BACKGROUND: To evaluate and compare the utility of 18F-fluorocholine (18F-CH) PET/CT versus 3-Tesla multiparametric MRI (mpMRI) without endorectal coil to detect tumor recurrences in patients with biochemical relapse following radical prostatectomy (RP). Secondarily, to identify possible prognostic variables associated with mpMRI and 18F-CH PET/CT findings. METHODS: Retrospective study of 38 patients who developed biochemical recurrence after RP between the years 2011 and 2015 at our institution...
December 7, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27923396/how-we-read-fch-pet-ct-for-prostate-cancer
#2
REVIEW
Jean-Mathieu Beauregard, Alexis Beaulieu
Over the last decade, (18)F-fluorocholine positron emission tomography/computed tomography (FCH-PET/CT) has gained in popularity for the staging and restaging of patients with prostate cancer (PCa). However, despite abundant literature on the topic, there is a lack of publications on how to actually interpret FCH-PET/CT in a clinical setting. Here we propose a practical, TNM-oriented approach to read FCH-PET/CT, with notes on procedure technique, image display, review sequence and report structure. The purpose of this article is to provide guidance to radiologists, nuclear medicine physicians and residents who are new to FCH-PET/CT, as well as to propose an alternate approach to more experienced physicians...
December 6, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27894359/can-morphological-mri-differentiate-between-primary-central-nervous-system-lymphoma-and-glioblastoma
#3
H Malikova, E Koubska, J Weichet, J Klener, A Rulseh, R Liscak, Z Vojtech
BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a rare, aggressive brain neoplasm that accounts for roughly 2-6% of primary brain tumors. In contrast, glioblastoma (GBM) is the most frequent and severe glioma subtype, accounting for approximately 50% of diffuse gliomas. The aim of the present study was to evaluate morphological MRI characteristics in histologically-proven PCNSL and GBM at the time of their initial presentation. METHODS: We retrospectively evaluated standard diagnostic MRI examinations in 54 immunocompetent patients (26 female, 28 male; age 62...
November 29, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27821180/utility-of-suvmax-on-18-f-fdg-pet-in-detecting-cervical-nodal-metastases
#4
Rebecca S M Lim, Shakher Ramdave, Paul Beech, Baki Billah, Md Nazmul Karim, Julian A Smith, Adnan Safdar, Elizabeth Sigston
BACKGROUND: The presence of cervical lymph node metastasis is an important prognostic factor for patients with head and neck squamous cell carcinomas (HNSCC). Accurate assessment of lymph node metastasis in these patients is essential for appropriate prognostic and management purposes. Here, we evaluated the effectiveness of the maximum standardized uptake value (SUVmax) on positron emission tomography (PET) in assessing lymph node metastasis in HNSCC prior to surgery. METHODS: A retrospective review of 74 patients with HNSCC who underwent PET/CT prior to neck dissection were examined...
November 8, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27814768/impact-of-3t-multiparametric-mri-and-fdg-pet-ct-in-the-evaluation-of-occult-primary-cancer-with-cervical-node-metastasis
#5
Mária Gődény, Zsolt Lengyel, Gábor Polony, Zoltán Takácsi Nagy, Gergely Léránt, Orsolya Zámbó, Éva Remenár, László Tamás, Miklós Kásler
BACKGROUND: This study aimed to determine the ability of multimodal evaluation with multiparametric 3T-MRI (MPMRI) and positron emission tomography - computed tomography (PET/CT) to detect cancer of unknown primary origin (CUP) with neck lymph node (LN) metastasis. METHODS: The study group comprised 38 retrospectively analysed consecutive patients with LN metastasis in the head and neck (HN) region without known primary tumours (PTs). Statistical values of 3T-MRI and of FDG-PET/CT scans were evaluated...
November 4, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27809936/impact-of-combined-fdg-pet-ct-and-mri-on-the-detection-of-local-recurrence-and-nodal-metastases-in-thyroid-cancer
#6
Johann-Martin Hempel, Roman Kloeckner, Sandra Krick, Daniel Pinto Dos Santos, Simin Schadmand-Fischer, Patrick Boeßert, Sotirios Bisdas, Matthias M Weber, Christian Fottner, Thomas J Musholt, Mathias Schreckenberger, Matthias Miederer
BACKGROUND: Suspected recurrence of thyroid carcinoma is a diagnostic challenge when findings of both a radio iodine whole body scan and ultrasound are negative. PET/CT and MRI have shown to be feasible for detection of recurrent disease. However, the added value of a consensus reading by the radiologist and the nuclear medicine physician, which has been deemed to be helpful in clinical routines, has not been investigated. This study aimed to investigate the impact of combined FDG-PET/ldCT and MRI on detection of locally recurrent TC and nodal metastases in high-risk patients with special focus on the value of the multidisciplinary consensus reading...
November 3, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27760565/erratum-to-a-method-to-assess-image-quality-for-low-dose-pet-analysis-of-snr-cnr-bias-and-image-noise
#7
Jianhua Yan, Josh Schaefferkoetter, Maurizio Conti, David Townsend
No abstract text is available yet for this article.
October 19, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27756360/how-we-read-oncologic-fdg-pet-ct
#8
REVIEW
Michael S Hofman, Rodney J Hicks
(18)F-fluorodeoxyglucose (FDG) PET/CT is a pivotal imaging modality for cancer imaging, assisting diagnosis, staging of patients with newly diagnosed malignancy, restaging following therapy and surveillance. Interpretation requires integration of the metabolic and anatomic findings provided by the PET and CT components which transcend the knowledge base isolated in the worlds of nuclear medicine and radiology, respectively. In the manuscript we detail our approach to reviewing and reporting a PET/CT study using the most commonly used radiotracer, FDG...
October 18, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27751167/effects-of-capecitabine-treatment-on-the-uptake-of-thymidine-analogs-using-exploratory-pet-imaging-agents-18-f-fau-18-f-fmau-and-18-f-flt
#9
Christopher I McHugh, Jawana M Lawhorn-Crews, Dipenkumar Modi, Kirk A Douglas, Steven K Jones, Thomas J Mangner, Jerry M Collins, Anthony F Shields
BACKGROUND: A principal goal for the use of positron emission tomography (PET) in oncology is for real-time evaluation of tumor response to chemotherapy. Given that many contemporary anti-neoplastic agents function by impairing cellular proliferation, it is of interest to develop imaging modalities to monitor these pathways. Here we examined the effect of capecitabine on the uptake of thymidine analogs used with PET: 3'-deoxy-3'-[(18)F]fluorothymidine ((18)F-FLT), 1-(2'-deoxy-2'-[(18)F]fluoro-β-D-arabinofuranosyl) thymidine ((18)F-FMAU), and 1-(2'-deoxy-2'-[(18)F]fluoro-β-D-arabinofuranosyl) uracil ((18)F-FAU) in patients with advanced cancer...
October 17, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27724954/single-source-chest-abdomen-pelvis-cancer-staging-on-a-third-generation-dual-source-ct-system-comparison-of-automated-tube-potential-selection-to-second-generation-dual-source-ct
#10
Clara Park, Tatjana Gruber-Rouh, Doris Leithner, Amelie Zierden, Mortiz H Albrecht, Julian L Wichmann, Boris Bodelle, Mohamed Elsabaie, Jan-Erik Scholtz, Moritz Kaup, Thomas J Vogl, Martin Beeres
BACKGROUND: Evaluation of latest generation automated attenuation-based tube potential selection (ATPS) impact on image quality and radiation dose in contrast-enhanced chest-abdomen-pelvis computed tomography examinations for gynaecologic cancer staging. METHODS: This IRB approved single-centre, observer-blinded retrospective study with a waiver for informed consent included a total of 100 patients with contrast-enhanced chest-abdomen-pelvis CT for gynaecologic cancer staging...
October 10, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27716452/comparison-of-computed-tomography-features-between-follicular-neoplasm-and-nodular-hyperplasia
#11
Kwang Hwi Lee, Dong Wook Kim, Jin Wook Baek, Yoo Jin Lee, Hye Jung Choo, Young Jun Cho, Sun Joo Lee, Young Mi Park, Soo Jin Jung, Hye Jin Baek
BACKGROUND: To date, appropriate management for Bethesda IV thyroid nodules is controversial, and no specific features of follicular neoplasm and nodular hyperplasia on ultrasonography, computed tomography (CT), or other imaging modalities have been reported. This study aimed to compare CT features of follicular neoplasm and nodular hyperplasia and to determine the specific CT features that could be used to distinguish follicular neoplasm from nodular hyperplasia. METHODS: In 122 patients who underwent preoperative CT of the neck and thyroid surgery, 59 follicular neoplasms and 65 nodular hyperplasias were included...
October 3, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27716376/lipiodol-retention-pattern-assessed-by-cone-beam-computed-tomography-during-conventional-transarterial-chemoembolization-of-hepatocellular-carcinoma-accuracy-and-correlation-with-response
#12
Jungang Hu, Majid Maybody, Guang Cao, Xiao Wang, Hui Chen, Xu Zhu, Renjie Yang, Xiaodong Wang
BACKGROUND: To investigate accuracy of intraprocedural cone beam computed tomography (CBCT) compared to fluoroscopy for detection of lipiodol retention pattern during conventional transarterial chemoembolization (cTACE) of hepatocellular carcinoma (HCC) and its correlation with short-term response. METHODS: Between September 2013 and July 2014, 29 patients with HCC underwent chemoembolization of 51 tumors (mean diameter 28.1 mm, range 10.0-136.3 mm). Lipiodol retention pattern was assessed by CBCT at the endpoint of cTACE compared by fluoroscopy...
October 3, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27604900/a-study-on-the-value-of-computer-assisted-assessment-for-spect-ct-scans-in-sentinel-lymph-node-diagnostics-of-penile-cancer-as-well-as-clinical-reliability-and-morbidity-of-this-procedure
#13
Ulf Lützen, Carsten Maik Naumann, Marlies Marx, Yi Zhao, Michael Jüptner, René Baumann, László Papp, Norbert Zsótér, Alexey Aksenov, Klaus-Peter Jünemann, Maaz Zuhayra
BACKGROUND: Because of the increasing importance of computer-assisted post processing of image data in modern medical diagnostic we studied the value of an algorithm for assessment of single photon emission computed tomography/computed tomography (SPECT/CT)-data, which has been used for the first time for lymph node staging in penile cancer with non-palpable inguinal lymph nodes. In the guidelines of the relevant international expert societies, sentinel lymph node-biopsy (SLNB) is recommended as a diagnostic method of choice...
September 7, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27581366/detection-of-a-second-malignancy-in-prostate-cancer-patients-by-using-18-f-choline-pet-ct-a-case-series
#14
Martina Sollini, Francesco Pasqualetti, Marzio Perri, Gabriele Coraggio, Paolo Castellucci, Massimo Roncali, Roberto Boni, Elena Lazzeri, Maria Galeandro, Fabiola Paiar, Annibale Versari, Paola Anna Erba
BACKGROUND: The role of radiolabeled choline (Cho) in patients with biochemical recurrence after radical treatment for prostate cancer (PCa) is well established. Its widespread clinical use has prompted the depiction of incidentalomas, unusual sites of metastatic lesions, as well as false positive and negative cases. We reported a series of patients affected by biochemical recurrence of PCa imaged by [(18)F]Cho positron emission tomography/computed tomography (PET/CT) which resulted suspected for a second malignancy...
August 31, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27565136/a-method-to-assess-image-quality-for-low-dose-pet-analysis-of-snr-cnr-bias-and-image-noise
#15
Jianhua Yan, Josh Schaefferkoette, Maurizio Conti, David Townsend
BACKGROUND: Lowering injected dose will have an effect on PET image quality. In this article, we aim to investigate this effect in terms of signal-to-noise ratio (SNR) in the liver, contrast-to-noise ratio (CNR) in the lesion, bias and ensemble image noise. METHODS: We present here our method and preliminary results using tuberculosis (TB) cases. Sixteen patients who underwent (18)F-FDG PET/MR scans covering the whole lung and portion of the liver were selected for the study...
August 26, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27549094/diagnostic-value-of-3-0t-1-h-mrs-with-choline-containing-compounds-ratio-%C3%A2-ccc-in-primary-malignant-hepatic-tumors
#16
Li Zhang, Xinming Zhao, Han Ouyang, Shuang Wang, Chunwu Zhou
BACKGROUND: The purpose of this study was to investigate the diagnostic value of 3.0-T (1)H magnetic resonance spectroscopy ((1)H MRS) in primary malignant hepatic tumors and to compare the effects of (1)H MRS on the diagnostic accuracy of liver-occupying lesions between junior and experienced radiologists. METHODS: This study included 50 healthy volunteers and 40 consecutive patients (50 lesions). Informed consent was obtained from each subject. Images were obtained on clinical whole-body 3...
August 22, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27544383/gallium-68-perfusion-positron-emission-tomography-computed-tomography-to-assess-pulmonary-function-in-lung-cancer-patients-undergoing-surgery
#17
Pierre-Yves Le Roux, Tracy L Leong, Stephen A Barnett, Rodney J Hicks, Jason Callahan, Peter Eu, Renee Manser, Michael S Hofman
BACKGROUND: Pre-operative evaluation of lung cancer patients relies on calculation of predicted post-operative (PPO) lung function based on split lung function testing. Pulmonary perfusion (Q) PET/CT can now be performed by substituting Technetium-99 m labeling of macroaggregated albumin (MAA) with Gallium-68. This study compares Q PET/CT with current recommended methods of pre-operative lung function assessment. METHODS: Twenty-two patients planned for curative surgical resection (mean FEV1 77 %, SD 21 %; mean DLCO 66 %, SD 17 % predicted) underwent pre-operative Q PET/CT...
August 20, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27542718/functional-mri-for-the-prediction-of-treatment-response-in-head-and-neck-squamous-cell-carcinoma-potential-and-limitations
#18
REVIEW
Ann D King, Harriet C Thoeny
Pre-treatment or early intra-treatment prediction of patients with head and neck squamous cell carcinomas (HNSCC) who are likely to have tumours that are resistant to chemoradiotherapy (CRT) would enable treatment regimens to be changed at an early time point, or allow patients at risk of residual disease to be targeted for more intensive post-treatment investigation. Research into the potential advantages of using functional-based magnetic resonance imaging (MRI) sequences before or during cancer treatments to predict treatment response has been ongoing for several years...
August 19, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27535829/-68-ga-dotatate-and-18-f-fdg-pet-ct-in-paraganglioma-and-pheochromocytoma-utility-patterns-and-heterogeneity
#19
Chian A Chang, David A Pattison, Richard W Tothill, Grace Kong, Tim J Akhurst, Rodney J Hicks, Michael S Hofman
BACKGROUND: Pheochromocytomas (PCC) and paragangliomas (PGL) are neuroendocrine tumours arising from pluripotent neural crest stem cells and are associated with neurons of the autonomic nervous system. PCCs/PGLs are often hereditary and multifocal, and their biologic behaviour and metabolic activity vary making imaging of these tumours challenging. The imaging gold standard has been I-123 MIBG complemented by CT or MRI. PGLs being neuroendocrine tumours express somatostatin receptors enabling imaging with Ga-68 DOTA-coupled peptides such as DOTATATE...
August 17, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27526937/mri-of-paediatric-liver-tumours-how-we-review-and-report
#20
REVIEW
Susan C Shelmerdine, Derek J Roebuck, Alexander J Towbin, Kieran McHugh
Liver tumours are fortunately rare in children. Benign tumours such as haemangiomas and cystic mesenchymal hamartomas are typically seen in infancy, often before 6 months of age. After that age, malignant hepatic tumours increase in frequency. The differentiation of a malignant from benign lesion on imaging can often negate the need for biopsy. Ultrasound is currently the main screening tool for suspected liver pathology, and is ideally suited for evaluation of hepatic lesions in children due to their generally small size...
August 15, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
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