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Cancer Imaging: the Official Publication of the International Cancer Imaging Society

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https://www.readbyqxmd.com/read/29784058/fat-suppressed-gadolinium-enhanced-isotropic-high-resolution-3d-gre-t1wi-for-predicting-small-node-metastases-in-patients-with-rectal-cancer
#1
Yan Chen, Xinyue Yang, Ziqiang Wen, Baolan Lu, Xiaojuan Xiao, Bingqi Shen, Shenping Yu
BACKGROUND: To investigate the application value of fat-suppressed gadolinium-enhanced isotropic high-resolution 3D-GRE-T1WI in regional nodes with different short-axis diameter ranges in rectal cancer, especially in nodes ≤5 mm. METHODS: Patients with rectal adenocarcinoma confirmed by postoperative histopathology were included, and all the patients underwent preoperative 3.0 T rectal magnetic resonance imaging (MRI) and total mesorectal excision (TME) within 2 weeks after an MR scan...
May 21, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29769114/-68-ga-psma-pet-ct-for-the-evaluation-of-pulmonary-metastases-and-opacities-in-patients-with-prostate-cancer
#2
Jonathan Damjanovic, Jan-Carlo Janssen, Christian Furth, Gerd Diederichs, Thula Walter, Holger Amthauer, Marcus R Makowski
BACKGROUND: The purpose of this study was to investigate the imaging properties of pulmonary metastases and benign opacities in 68 Ga-PSMA positron emission tomography (PET) in patients with prostate cancer (PC). METHODS: 68 Ga-PSMA-PET/CT scans of 739 PC patients available in our database were evaluated retrospectively for lung metastases and non-solid focal pulmonary opacities. Maximum standardized uptake values (SUVmax ) were assessed by two- and three-dimensional regions of interest (2D/3D ROI)...
May 16, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29764500/the-role-of-initial-18-f-fdg-pet-ct-in-the-management-of-patients-with-suspected-extramedullary-plasmocytoma
#3
Linqi Zhang, Xu Zhang, Qiao He, Rusen Zhang, Wei Fan
BACKGROUND: Extramedullary plasmacytoma (EMP) is a plasma cell malignancy that originates in soft tissues without evidence of systemic spread, and its management differs from other plasma cell neoplasms. The purpose of the present study was to evaluate the role of initial 18 F-FDG PET/CT in the management of patients with clinical suspected EMP. METHODS: 18 F-FDG PET/CT scans performed in 21 patients (M/F = 12/9, mean age 51.1 ± 15.3 years) with clear suspicion of EMP from 2006 to 2015 were analysed retrospectively...
May 15, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29728140/solid-component-proportion-is-an-important-predictor-of-tumor-invasiveness-in-clinical-stage-t-1-n-0-m-0-ct-1-n-0-m-0-lung-adenocarcinoma
#4
Meng Li, Ning Wu, Li Zhang, Wei Sun, Ying Liu, Lv Lv, Jiansong Ren, Dongmei Lin
BACKGROUND: Preoperative tumor invasiveness in clinical stage T1 N0 M0 lung adenocarcinoma is critical for optimal surgical procedure. The aim of the present study was to evaluate the relationship between the ground-glass opacity component (GGOc) / solid component (Sc) proportion measured using three-dimensional (3D) computer-quantified computer tomography (CT) number analysis to explore radiographic features for invasiveness prediction in cT1 N0 M0 lung adenocarcinomas. METHODS: A total of 375 surgically resected cT1 N0 M0 lung adenocarcinoma patients were included...
May 4, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29724245/renal-cell-carcinoma-with-venous-extension-prediction-of-inferior-vena-cava-wall-invasion-by-mri
#5
Lisa C Adams, Bernhard Ralla, Yi-Na Y Bender, Keno Bressem, Bernd Hamm, Jonas Busch, Florian Fuller, Marcus R Makowski
BACKGROUND: Renal cell carcinoma (RCC) are accompanied by inferior vena cava (IVC) thrombus in up to 10% of the cases, with surgical resection remaining the only curative option. In case of IVC wall invasion, the operative procedure is more challenging and may even require IVC resection. This study aims to determine the diagnostic performance of contrast-enhanced magnetic resonance imaging (MRI) for the assessment of wall invasion by IVC thrombus in patients with RCC, validated with intraoperative findings...
May 3, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29720249/image-quality-of-arterial-phase-and-parenchymal-blood-volume-pbv-maps-derived-from-c-arm-computed-tomography-in-the-evaluation-of-transarterial-chemoembolization
#6
Tanja Zitzelsberger, Roland Syha, Gerd Grözinger, Sasan Partovi, Konstantin Nikolaou, Ulrich Grosse
BACKGROUND: To evaluate the benefits of arterial phase imaging and parenchymal blood volume (PBV) maps acquired by C-arm computed tomography during TACE procedure in comparison to cross-sectional imaging (CSI) using CT or MRI. METHODS: From January 2014 to December 2016, a total of 29 patients with HCC stage A or B (mean age 65 years; range 47 to 81 years, 86% male) were included in this study. These patients were referred to our department for TACE treatment and received peri-interventional C-arm CT...
May 2, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29695290/an-international-survey-on-hybrid-imaging-do-technology-advances-preempt-our-training-and-education-efforts
#7
T Beyer, R Hicks, C Brun, G Antoch, L S Freudenberg
BACKGROUND: Hybrid PET/CT and PET/MRI are increasingly important technologies in the evaluation of malignancy and require cooperation between radiologists and specialists in molecular imaging. The aim of our study was to probe the mindsets of radiological and nuclear medicine professionals in regard to current hybrid imaging practice and to assess relevant training aspirations and perceived shortfalls, particularly amongst young professionals. In this context, we initiated an international survey on "Hybrid Imaging Training"...
April 26, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29690933/li-rads-v2017-for-liver-nodules-how-we-read-and-report
#8
REVIEW
Wolfgang Schima, Jay Heiken
The Liver Imaging Reporting and Data System (LI-RADS) standardizes the interpretation and reporting of imaging examinations in patients at risk for hepatocellular carcinoma (HCC). For focal liver observations it assigns categories (LR-1 to 5, LR-M, LR-TIV), which reflect the relative probability of benignity or malignancy of the respective observation. The categories assigned are based on major and ancillary image features, which have been developed by the American College of Radiology (ACR) and validated in many studies...
April 24, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29669600/review-of-targeted-therapy-in-chronic-lymphocytic-leukemia-what-a-radiologist-needs-to-know-about-ct-interpretation
#9
REVIEW
Babina Gosangi, Matthew Davids, Bhanusupriya Somarouthu, Francesco Alessandrino, Angela Giardino, Nikhil Ramaiya, Katherine Krajewski
The last 5 years have been marked by profound innovation in the targeted treatment of chronic lymphocytic leukemia (CLL) and indolent lymphomas. Using CLL as a case study, we present a timeline and overview of the current treatment landscape for the radiologist, including an overview of clinical and radiological features of CLL, discussion of the targeted agents themselves, and the role of imaging in response and toxicity assessment. The goal is to familiarize the radiologist with multiple Food and Drug Administration (FDA)-approved targeted agents used in this setting and associated adverse events which are commonly observed in this patient population...
April 18, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29653585/most-enhancing-tumor-volume-by-mri-radiomics-predicts-recurrence-free-survival-early-on-in-neoadjuvant-treatment-of-breast-cancer
#10
Karen Drukker, Hui Li, Natalia Antropova, Alexandra Edwards, John Papaioannou, Maryellen L Giger
BACKGROUND: The hypothesis of this study was that MRI-based radiomics has the ability to predict recurrence-free survival "early on" in breast cancer neoadjuvant chemotherapy. METHODS: A subset, based on availability, of the ACRIN 6657 dynamic contrast-enhanced MR images was used in which we analyzed images of all women imaged at pre-treatment baseline (141 women: 40 with a recurrence, 101 without) and all those imaged after completion of the first cycle of chemotherapy, i...
April 13, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29622044/ultrasound-shear-wave-elastography-of-breast-lesions-correlation-of-anisotropy-with-clinical-and-histopathological-findings
#11
Ya-Ling Chen, Yi Gao, Cai Chang, Fen Wang, Wei Zeng, Jia-Jian Chen
BACKGROUND: Ultrasound shear-wave elastography (SWE) may increase specificity of breast lesion assessment with ultrasound, but elasticity measurements may change with transducer orientation, defined as anisotropy. In this study, we aimed to observe the anisotropy of SWE of breast lesions, and its correlation with clinical and histopathological findings. METHODS: This retrospective study was approved by institutional review board. From June 2014 to June 2015, a total of 276 women (mean age, 48...
April 5, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29514710/added-value-of-diffusion-weighted-imaging-in-hepatic-tumors-and-its-impact-on-patient-management
#12
Jana Taron, Jonas Johannink, Michael Bitzer, Konstantin Nikolaou, Mike Notohamiprodjo, Rüdiger Hoffmann
BACKGROUND: To investigate the added diagnostic value of diffusion-weighted imaging (DWI) of the liver and its impact on therapy decisions in patients with hepatic malignancy. METHODS: Interdisciplinary gastrointestinal tumorboard cases concerning patients with hepatic malignancies discussed between 11/2015 and 06/2016 were included in this retrospective, single-center study. Two radiologists independently reviewed the respective liver MR-examination first without, then with DWI...
March 7, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29490696/imaging-features-of-fibrolamellar-hepatocellular-carcinoma-in-gadoxetic-acid-enhanced-mri
#13
Viktoria Palm, Ruofan Sheng, Philipp Mayer, Karl-Heinz Weiss, Christoph Springfeld, Arianeb Mehrabi, Thomas Longerich, Anne Katrin Berger, Hans-Ulrich Kauczor, Tim Frederik Weber
BACKGROUND: Fibrolamellar hepatocellular carcinoma (FLC) is a rare malignancy occurring in young patients without cirrhosis. Objectives of our study were to analyze contrast material uptake in hepatobiliary phase imaging (HBP) in gadoxetic acid-enhanced liver MRI in patients with FLC and to characterize imaging features in sequence techniques other than HBP. METHODS: In this retrospective study on histology-proven FLC, contrast material uptake in HBP was quantitatively assessed by calculating the corrected FLC enhancement index (CEI) using mean signal intensities of FLC and lumbar muscle on pre-contrast imaging and HBP, respectively...
March 1, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29486800/mri-features-of-combined-hepatocellular-cholangiocarcinoma-versus-mass-forming-intrahepatic-cholangiocarcinoma
#14
Jennifer Sammon, Sandra Fischer, Ravi Menezes, Hooman Hosseini-Nik, Sara Lewis, Bachir Taouli, Kartik Jhaveri
BACKGROUND: Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a rare primary liver tumor, which has overlapping imaging features with mass forming intra-hepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC). Previous studies reported imaging features more closely resemble ICC and the aim of our study was to examine the differential MRI features of cHCC-CC and ICC with emphasis on enhancement pattern observations of gadolinium enhanced MRI. METHODS: Institutional review board approval with consent waiver was obtained for this retrospective bi-centric study...
February 27, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29482629/primary-carcinosarcoma-of-the-liver-imaging-features-and-clinical-findings-in-six-cases-and-a-review-of-the-literature
#15
Jing Li, Pan Liang, Dandan Zhang, Jie Liu, Hongkai Zhang, Jinrong Qu, Jianbo Gao
BACKGROUND: Carcinosarcoma of the liver is a very rare tumor composed of a mixture of carcinomatous and sarcomatous elements. Less than 25 adequately documented cases have been reported, with inadequate description of imaging features. In order to improve the awareness of this rare tumor, this study aimed to analyze the clinicopathologic and imaging features of six cases of hepatic carcinosarcoma (HCS) confirmed by surgical pathologic evaluation. METHODS: We retrospectively studied the clinicopathologic and imaging features of six cases of HCS (matching the World Health Organization definition) and discussed the differential diagnosis on the basis of imaging findings...
February 27, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29471875/pre-treatment-dwi-as-a-predictor-of-overall-survival-in-locally-advanced-pancreatic-cancer-treated-with-cyberknife-radiotherapy-and-sequential-s-1-therapy
#16
Yu Zhang, Xiaofei Zhu, Denghui Liu, Jiaqi Song, Huojun Zhang, Jianping Lu
BACKGROUND: To identify the value of the pre-treatment apparent diffusion coefficient (ADC) derived from diffusion weighted imaging (DWI) in predicting the overall survival (OS) for locally advanced pancreatic cancer (LAPC) treated with Cyberknife followed by sequential S-1 chemotherapy. METHODS: Patients with UICC-T4 LAPC who underwent DWI scan (3.0 Tesla) using two b-values (0, 600 s/mm2 ) in our center between 2015 and 2017 were enrolled. Mean ADCs of the region of interest (ROI) drawn manually on DWI imaging were measured by two independent radiologists at an interval of 1 month...
February 22, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29422089/cement-pulmonary-embolism-as-a-complication-of-percutaneous-vertebroplasty-in-cancer-patients
#17
Asem Mansour, Nayef Abdel-Razeq, Hussein Abuali, Mohammad Makoseh, Nouran Shaikh-Salem, Kamelah Abushalha, Samer Salah
BACKGROUND: Vertebroplasty is a minimally invasive procedure commonly performed for vertebral compression fractures secondary to osteoporosis or malignancy. Leakage of bone cement into the paravertebral venous system and cement pulmonary embolism (cPE) are well described, mostly in patients with osteoporosis. Little is known about the clinical sequelae and outcomes in cancer patients. In this study, we report our experience with cPE following vertebroplasty performed in cancer patients...
February 8, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29378659/diagnostic-performance-of-18-f-fdg-pet-ct-using-point-spread-function-reconstruction-on-initial-staging-of-rectal-cancer-a-comparison-study-with-conventional-pet-ct-and-pelvic-mri
#18
Masatoshi Hotta, Ryogo Minamimoto, Hideaki Yano, Yoshimasa Gohda, Yasutaka Shuno
BACKGROUND: Accurate staging is crucial for treatment selection and prognosis prediction in patients with rectal cancer. Point spread function (PSF) reconstruction can improve spatial resolution and signal-to-noise ratio of PET imaging. The aim of this study was to evaluate the effectiveness of 18 F-FDG PET/CT with PSF reconstruction for initial staging in rectal cancer compared with conventional PET/CT and pelvic MRI. METHODS: A total of 59 patients with rectal cancer underwent preoperative 18 F-FDG PET/CT and pelvic MRI...
January 30, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29361984/changes-in-biodistribution-on-68-ga-dota-octreotate-pet-ct-after-long-acting-somatostatin-analogue-therapy-in-neuroendocrine-tumour-patients-may-result-in-pseudoprogression
#19
Martin H Cherk, Grace Kong, Rodney J Hicks, Michael S Hofman
BACKGROUND: To evaluate the effects of long-acting somatostatin analogue (SSA) therapy on 68 Ga-DOTA-octreotate (GaTate) uptake at physiological and metastatic sites in neuroendocrine tumour (NET) patients. METHODS: Twenty-one patients who underwent GaTate PET/CT before and after commencement of SSA therapy were reviewed. Maximum standardized uptake values (SUVmax) were measured in normal organs. Changes in uptake of 49 metastatic lesions in 12 patients with stable disease were also compared...
January 24, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29347968/-18-f-fdg-pet-ct-and-diffusion-weighted-mri-for-monitoring-a-braf-and-cdk-4-6-inhibitor-combination-therapy-in-a-murine-model-of-human-melanoma
#20
Ralf S Eschbach, Philipp M Kazmierczak, Maurice M Heimer, Andrei Todica, Heidrun Hirner-Eppeneder, Moritz J Schneider, Georg Keinrath, Olga Solyanik, Jessica Olivier, Wolfgang G Kunz, Maximilian F Reiser, Peter Bartenstein, Jens Ricke, Clemens C Cyran
BACKGROUND: The purpose of the study was to investigate a novel BRAF and CDK 4/6 inhibitor combination therapy in a murine model of BRAF-V600-mutant human melanoma monitored by 18 F-FDG-PET/CT and diffusion-weighted MRI (DW-MRI). METHODS: Human BRAF-V600-mutant melanoma (A375) xenograft-bearing balb/c nude mice (n = 21) were imaged by 18 F-FDG-PET/CT and DW-MRI before (day 0) and after (day 7) a 1-week BRAF and CDK 4/6 inhibitor combination therapy (n = 12; dabrafenib, 20 mg/kg/d; ribociclib, 100 mg/kg/d) or placebo (n = 9)...
January 18, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
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