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World Journal of Surgical Oncology

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https://www.readbyqxmd.com/read/28806962/oncofertility-in-patients-with-stage-i-epithelial-ovarian-cancer-fertility-sparing-surgery-in-young-women-of-reproductive-age
#1
Xuan Jiang, Jiaxin Yang, Mei Yu, Weimin Xie, Dongyan Cao, Ming Wu, Lingya Pan, Huifang Huang, Yan You, Keng Shen
BACKGROUND: Fertility-sparing surgery is indicated for patients with stage I epithelial ovarian cancers. We sought to evaluate the clinical outcomes and oncofertility in a cohort of patients of reproductive age with stage I epithelial ovarian cancer (EOC). METHODS: Overall, 108 patients of reproductive age (≤ 40 years) diagnosed with stage I EOC who were treated at Peking Union Medical College Hospital between 1999 and 2013 were included in the study. The Kaplan-Meier model and Cox regression analyses were used for the survival analysis...
August 15, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28807031/inflammation-and-pro-resolution-inflammation-after-hepatobiliary-surgery
#2
Juan P Cata, Jose F Velasquez, Maria F Ramirez, Jean-Nicolas Vauthey, Vijaya Gottumukkala, Claudius Conrad, Bradford J Kim, Thomas Aloia
BACKGROUND: The magnitude of the perioperative inflammatory response plays a role in surgical outcomes. However, few studies have explored the mechanisms of the resolution of inflammation in the context of surgery. Here, we described the temporal kinetics of interleukin-6, cortisol, lipoxin A4, and resolvin D in patients who underwent oncologic liver resections. METHODS: All patients gave written informed consent. Demographic and perioperative surgical data were collected, along with blood samples, before surgery and on the mornings of postoperative days 1, 3, and 5...
August 10, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28797257/identification-of-key-lncrnas-in-colorectal-cancer-progression-based-on-associated-protein-protein-interaction-analysis
#3
Haishan Zhu, Jiajing Yu, Haifeng Zhu, Yusheng Guo, Shengjie Feng
BACKGROUND: Colorectal cancer (CRC) was one of the most commonly diagnosed malignancies. The molecular mechanisms involved in the progression of CRC remain unclear. Accumulating evidences showed that long noncoding RNAs (lncRNAs) played key roles in tumorigenesis, cancer progression, and metastasis. Therefore, we aimed to explore the roles of lncRNAs in the progression of CRC. METHODS: In this study, we aimed to identify differentially expressed lncRNAs and messenger RNAs (mRNAs) in CRC by analyzing a cohort of previously published datasets: GSE64857...
August 10, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28789700/two-different-protein-expression-profiles-of-oral-squamous-cell-carcinoma-analyzed-by-immunoprecipitation-high-performance-liquid-chromatography
#4
Soung Min Kim, Dasul Jeong, Min Keun Kim, Sang Shin Lee, Suk Keun Lee
BACKGROUND: Oral squamous cell carcinoma (OSCC) is one of the most dangerous cancers in the body, producing serious complications with individual behaviors. Many different pathogenetic factors are involved in the carcinogenesis of OSCC. Cancer cells derived from oral keratinocytes can produce different carcinogenic signaling pathways through differences in protein expression, but their protein expression profiles cannot be easily explored with ordinary detection methods. METHODS: The present study compared the protein expression profiles between two different types of OSCCs, which were analyzed through immunoprecipitation high-performance liquid chromatography (IP-HPLC)...
August 8, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28789662/predictive-factors-of-prolonged-mechanical-ventilation-overall-survival-and-quality-of-life-in-patients-with-post-thymectomy-myasthenic-crisis
#5
Kun-Kun Li, Kai Qian, Yong-Geng Feng, Wei Guo, Qun-You Tan, Bo Deng
BACKGROUND: Thymectomy is the primary approach for the treatment of myasthenia gravis (MG). This retrospective study aimed to identify the clinical and demographical features that may impact the duration of mechanical ventilation (DMV), the long-term survival, and the quality of life (QOL) in patients with post-thymectomy myasthenic crisis (PTMC). METHODS: We reviewed the patients who suffered from PTMC from June 2008 to November 2015. Cox proportional hazard regression analysis was used to identify potential prognostic factors that may impact DMV and long-term survival...
August 8, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28774331/treating-cancerous-large-airway-stenosis-with-staging-radioactive-particle-implantation-guided-by-computed-tomography-and-fiber-bronchoscopy-a-clinical-study
#6
Yu Mao, Xiuyan Yang, Ming Li, Wei Guo, Wenhua Zhang
BACKGROUND: The purpose of this study is to investigate the clinical effectiveness of staging radioactive particle implantation guided by computed tomography (CT) and fiber-optic bronchoscopy in treating cancerous large airway stenosis. METHODS: A total of 102 patients were included; 57 had undergone staging radioactive particle implantation guided by CT and fiber bronchoscopy and 45 did not. Patients were evaluated by CT and fiber-optic bronchoscopy to determine the feasibility of the implantation of radioactive seeds for the treatment of cancerous large airway stenosis...
August 3, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28774330/the-paradigm-of-tumor-shrinkage-and-rapid-liver-remnant-hypertrophy-for-conversion-of-initially-unresectable-colorectal-liver-metastasis-a-case-report-and-literature-review
#7
Nan Xiao, Kailin Yu, Shaojun Yu, Jianjun Wu, Jian Wang, Siyang Shan, Shuchun Zheng, Liuhong Wang, Jianwei Wang, Shuyou Peng
BACKGROUND: For colorectal liver metastasis (CRLM) patients, hepatic resection is currently the sole cure offering the chance of long-term survival. Tumor shrinkage and planned liver remnant hypertrophy are the two key strategies for conversion of initially unresectable CRLM. First conducted in 2012, associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) allows rapid liver growth. As a means to induce hypertrophy, portal vein embolization (PVE) has been widely applied before extending hepatectomy...
August 3, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28774300/diagnostic-significance-of-micrornas-as-novel-biomarkers-for-bladder-cancer-a-meta-analysis-of-ten-articles
#8
Hong-Bin Shi, Jia-Xing Yu, Jian-Xiu Yu, Zheng Feng, Chao Zhang, Guang-Yong Li, Rui-Ning Zhao, Xiao-Bo Yang
BACKGROUND: Previous studies have revealed the importance of microRNAs' (miRNAs) function as biomarkers in diagnosing human bladder cancer (BC). However, the results are discordant. Consequently, the possibility of miRNAs to be BC biomarkers was summarized in this meta-analysis. METHODS: In this study, the relevant articles were systematically searched from CBM, PubMed, EMBASE, and Chinese National Knowledge Infrastructure (CNKI). The bivariate model was used to calculate the pooled diagnostic parameters and summary receiver operator characteristic (SROC) curve in this meta-analysis, thereby estimating the whole predictive performance...
August 3, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28768544/preoperative-endoscopic-titanium-clip-placement-facilitates-intraoperative-localization-of-early-stage-esophageal-cancer-or-severe-dysplasia
#9
Lei Tan, Juan Feng, Qin Zhao, Ping Chen, Guotao Yang
BACKGROUND: Accurate intraoperative localization of esophageal lesions is essential for successful surgical resection. We tested whether preoperative endoscopic placement of titanium clips could facilitate intraoperative localization of early-stage esophageal cancer or severe dysplasia. METHODS: A prospective randomized clinical trial was performed between May 2012 and July 2014. All enrolled patients received preoperative endoscopy and esophageal endoscopic ultrasound, as well as pathological study on the biopsy specimen, to confirm early stage esophageal cancer or severe dysplasia...
August 2, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28768520/colorectal-cancer-in-a-patient-with-intestinal-schistosomiasis-a-case-report-from-kilimanjaro-christian-medical-center-northern-zone-tanzania
#10
Ayesiga M Herman, Alfred Kishe, Heri Babu, Hilary Shilanaiman, Murad Tarmohamed, Jay Lodhia, Patrick Amsi, Jeremia Pyuza, Alex Mremi, Amos Mwasamwaja, Mramba Nyindo, Kondo Chilonga, David Msuya
BACKGROUND: Colorectal cancer associated with chronic intestinal schistosomiasis has been linked with the chronic inflammation as a result of schistosomal ova deposition in the submucosal layer of the intestine. Among all species Schistosoma japonicum has been more linked to development of colorectal cancer as compared to Schistosoma mansoni due to absence of population-based studies to support the association. Despite the weak evidence, some cases have been reported associating S. mansoni with development of colorectal cancer...
August 2, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28764808/association-between-mpo-463g%C3%A2-%C3%A2-a-polymorphism-and-cancer-risk-evidence-from-60-case-control-studies
#11
REVIEW
Wen-Jun Yang, Ming-Yue Wang, Fu-Ze Pan, Chen Shi, Hong Cen
BACKGROUND: Though a number of studies have been conducted to explore the association between myeloperoxidase (MPO)-463G > A polymorphism and cancer risk, the results remain inconsistent. Therefore, we performed a meta-analysis to derive a more systematic estimation of this relationship. METHOD: Relevant studies were searched by PubMed, EMBASE, CNKI, Google Scholar, Ovid, and Cochrane library prior to December 2015. The strength of the association between MPO-463G > A polymorphism and cancer risk was estimated by odds ratios (OR) with 95% confidence interval (95%CI)...
August 2, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28764791/metachronous-colorectal-carcinoma-with-massive-submucosal-invasion-detected-by-annual-surveillance-in-a-lynch-syndrome-patient-a-case-report
#12
Masashi Utsumi, Kohji Tanakaya, Yutaka Mushiake, Tomoyoshi Kunitomo, Isao Yasuhara, Fumitaka Taniguchi, Takashi Arata, Koh Katsuda, Hideki Aoki, Hitoshi Takeuchi
BACKGROUND: Lynch syndrome is the most common form of hereditary colorectal carcinoma. It is characterized by the presence of germline mutations in DNA mismatch repair genes. Mutation carriers have a lifetime risk of developing colorectal carcinoma of approximately 80%. Current treatment guidelines recommend periodic surveillance for colorectal carcinoma in patients with Lynch syndrome. However, the optimal interval between colonoscopies has not yet been determined. CASE PRESENTATION: We describe a 54-year-old man with Lynch syndrome who was undergoing annual colonoscopy surveillance for the development of colorectal carcinoma...
August 1, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28764790/successful-management-of-rare-gingival-metastasis-from-gastric-adenocarcinoma-a-case-report-and-literature-review
#13
Zhili Wu, Jun Tang, Yan Li, Husheng Lu, Jun Xu, Donglai Lv
BACKGROUND: Gastric cancer rarely metastasizes to the oral cavity, especially to gingiva. Only 18 cases have been reported worldwide to date. This paper herein presents the nineteenth case of gingival metastasis from gastric cancer. CASE PRESENTATION: A 75-year-old man who underwent a radical gastrectomy for gastric adenocarcinoma was admitted to clinical oncology center for gingival mass which was originally diagnosed as epulis. The subsequent positron emission tomography-computed tomography (PET-CT) and histopathological examination revealed a gingival metastatic adenocarcinoma originated from gastric carcinoma...
August 1, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28764784/e-cadherin-expression-phenotypes-associated-with-molecular-subtypes-in-invasive-non-lobular-breast-cancer-evidence-from-a-retrospective-study-and-meta-analysis
#14
Jiang-Bo Liu, Chen-Yi Feng, Miao Deng, Dong-Feng Ge, De-Chun Liu, Jian-Qiang Mi, Xiao-Shan Feng
BACKGROUND: This retrospective study and meta-analysis was designed to explore the relationship between E-cadherin (E-cad) expression and the molecular subtypes of invasive non-lobular breast cancer, especially in early-stage invasive ductal carcinoma (IDC). METHODS: A total of 156 post-operative cases of early-stage IDCs were retrospectively collected for the immunohistochemistry (IHC) detection of E-cad expression. The association of E-cad expression with molecular subtypes of early-stage IDCs was analyzed...
August 1, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28764712/sclerosing-mesenteritis-mimicking-metachronous-peritoneal-metastases-from-descending-colon-adenocarcinoma
#15
Toshifumi Watanabe, Shiro Terai, Tomoya Tsukada, Masaki Takeshita, Koshi Matsui, Koji Amaya, Masahide Kaji, Kiichi Maeda, Koichi Shimizu, Junko Saito, Kentaro Mochizuki, Akio Uchiyama
BACKGROUND: Sclerosing mesenteritis is a non-neoplastic inflammatory disease that occurs in the bowel mesentery. Distinguishing sclerosing mesenteritis from neoplasms may be difficult because of the clinical and radiographic similarities between the two disease entities. CASE PRESENTATION: We report a case of sclerosing mesenteritis mimicking peritoneal metastases of colorectal carcinoma. A 73-year-old man with stage II descending colon adenocarcinoma with poor prognostic features was found to have developed left lower abdominal quadrant masses on computed tomography (CT) 9 months after undergoing radical surgery...
August 1, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28764707/delayed-anastomotic-leakage-following-laparoscopic-intersphincteric-resection-for-lower-rectal-cancer-report-of-four-cases-and-literature-review
#16
Masayoshi Iwamoto, Kenji Kawada, Koya Hida, Suguru Hasegawa, Yoshiharu Sakai
BACKGROUND: Anastomotic leakage (AL) is one of the most dreadful postoperative complications because it can result in increased morbidity and mortality as well as poorer long-term prognosis. Although most studies of AL limited their investigation time to a period of 30 days postoperatively, only a few studies have shown that AL can occur after that period. Here, we report four patients of rectal cancer with delayed AL following laparoscopic intersphincteric resection (ISR) and conduct a literature review on delayed AL...
August 1, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28750680/primary-tumor-location-as-a-predictor-of-the-benefit-of-palliative-resection-for-colorectal-cancer-with-unresectable-metastasis
#17
Rong-Xin Zhang, Wen-Juan Ma, Yu-Ting Gu, Tian-Qi Zhang, Zhi-Mei Huang, Zhen-Hai Lu, Yang-Kui Gu
BACKGROUND: It is still under debate that whether stage IV colorectal cancer patients with unresectable metastasis can benefit from primary tumor resection, especially for asymptomatic colorectal cancer patients. Retrospective studies have shown controversial results concerning the benefit from surgery. This retrospective study aims to evaluate whether the site of primary tumor is a predictor of palliative resection in asymptomatic stage IV colorectal cancer patients. METHODS: One hundred ninety-four patients with unresectable metastatic colorectal cancer were selected from Sun Yat-sen University Cancer Center Database in the period between January 2007 and December 2013...
July 27, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28747182/recurrent-primary-mediastinal-giant-cell-tumor-of-soft-tissue-with-radiological-findings-a-rare-case-report-and-literature-review
#18
Qiongjie Hu, Jian Peng, Liming Xia
BACKGROUND: Giant cell tumor of soft tissue (GCT-ST), which histologically resembles GCT of bone, is a rare tumor. Usually, it is located in the lower extremities and trunk. GCT-ST, occurring in mediastinum, is extremely rare. CASE PRESENTATION: We encountered an 18-year-old Chinese woman who had mild dull pain on the left side of back. The following chest computed tomography (CT) showed a heterogeneous mass deeply situated in the posterior mediastinum with compression of the lung and invasion of the adjacent rib...
July 26, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28732507/long-noncoding-rna-expression-profiles-in-sub-lethal-heat-treated-hepatoma-carcinoma-cells
#19
Qingsong Deng, Shihan Chen, Chunchuan Fu, Jiayun Jiang, Mengda Zou, Yunhua Tan, Xiaofei Wang, Feng Xia, Kai Feng, Kuansheng Ma, Ping Bie
BACKGROUND: Sub-lethal heat treatment characterizes a transition zone of radiofrequency ablation (RFA) which explains hepatocellular carcinoma (HCC) residual cancer occurrence in this area after RFA treatment. The biochemistry of residual cancer cell recurrence is poorly understood, but long noncoding RNAs (lncRNAs) may have aberrant expression that is associated with diverse cancers. Thus, we measured lncRNA gene expression in sub-lethally heat-treated HCC cells using microarray. METHOD: Differentially expressed lncRNA and mRNA were measured with an Agilent Human lncRNA + mRNA Array V4...
July 21, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28716145/mortality-differences-by-surgical-volume-among-patients-with-stomach-cancer-a-threshold-for-a-favorable-volume-outcome-relationship
#20
Hyeok Choi, Seong-Yoon Yang, Hee-Seung Cho, Woorim Kim, Eun-Cheol Park, Kyu-Tae Han
BACKGROUND: Many studies have assessed the volume-outcome relationship in cancer patients, but most focused on better outcomes in higher volume groups rather than identifying a specific threshold that could assist in clinical decision-making for achieving the best outcomes. The current study suggests an optimal volume for achieving good outcome, as an extension of previous studies on the volume-outcome relationship in stomach cancer patients. METHODS: We used National Health Insurance Service (NHIS) Sampling Cohort data during 2004-2013, comprising healthcare claims for 2550 patients with newly diagnosed stomach cancer...
July 17, 2017: World Journal of Surgical Oncology
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