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World Journal of Surgical Oncology

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https://www.readbyqxmd.com/read/28629469/a-putative-molecular-network-associated-with-colon-cancer-metastasis-constructed-from-microarray-data
#1
Songtao Chu, Haipeng Wang, Miao Yu
BACKGROUND: This study aimed to identify the potential molecular network associated with colon cancer metastasis. METHODS: A gene expression profile dataset (GSE40367) downloaded from Gene Expression Omnibus was used to identify and compare differentially expressed genes (DEGs) between primary colon adenocarcinoma tissues and matched tissue samples of liver metastases of colon adenocarcinoma. After the functional analysis of the DEGs, their protein-protein interactions (PPIs) were analyzed, and the transcription factors (TFs) and microRNAs (miRNAs) that regulated these DEGs were predicted...
June 19, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28587656/the-correlations-between-dna-methylation-and-polymorphisms-in-the-promoter-region-of-the-human-telomerase-reverse-transcriptase-htert-gene-with-postoperative-recurrence-in-patients-with-thyroid-carcinoma-tc
#2
Jian-Jun Li, Ping Chen Jue-Ru Zheng, Yao-Zong Wang
BACKGROUND: This study aims at exploring the correlations between DNA methylation and polymorphisms in the promoter region of the human telomerase reverse transcriptase (hTERT) gene and postoperative recurrence in patients with thyroid carcinoma (TC). METHODS: A total of 312 patients diagnosed with TC were chosen for the study and categorized into recurrence (n = 75) and non-recurrence (n = 237) groups. The hTERT rs2736100 and rs2736098 polymorphisms were detected by performing polymerase chain reaction-restriction fragment length polymorphism...
June 6, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28577563/endoscopic-ultrasonography-compared-with-multidetector-computed-tomography-for-the-preoperative-staging-of-gastric-cancer-a-meta-analysis
#3
REVIEW
Run-Cong Nie, Shu-Qiang Yuan, Xiao-Jiang Chen, Shi Chen, Li-Pu Xu, Yong-Ming Chen, Bao-Yan Zhu, Xiao-Wei Sun, Zhi-Wei Zhou, Ying-Bo Chen
BACKGROUND: The current study sought to perform a meta-analysis to compare the preoperative staging of endoscopic ultrasonography (EUS) and multidetector computed tomography (MDCT) in gastric carcinoma. METHODS: Articles published between January 1, 2000, and April 1, 2016, that compared EUS with MDCT were included, and data were presented as 2 × 2 tables. The sensitivities, specificities and summary receiver operating characteristic (ROC) curves for T and N staging were calculated using a bivariate mixed effects model...
June 2, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28566093/efficacy-and-short-term-outcomes-of-preoperative-chemoradiotherapy-with-intermittent-oral-tegafur-uracil-plus-leucovorin-in-japanese-rectal-cancer-patients-a-single-center-experience-retrospective-analysis
#4
Ryosuke Nakagawa, Yuji Inoue, Takeshi Ohki, Yuka Kaneko, Fumi Maeda, Masakazu Yamamoto
BACKGROUND: Various types of preoperative chemoradiotherapy (CRT) have been established for rectal cancer; thus, Physicians will need to refine the selection of appropriate preoperative CRT for different patients since there are various treatment regimens. Oral tegafur-uracil (UFT) plus leucovorin (LV) is commonly used to treat rectal cancer in Japan. Oral chemotherapy offers patients many potential advantages. Since 2008, we have been performing preoperative CRT with intermittent oral UFT plus LV in locally advanced rectal cancer patients to prevent postoperative local recurrence...
May 31, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28558836/extraction-of-a-specimen-through-an-umbilical-zigzag-incision-during-laparoscopic-surgery-for-endometrial-cancer
#5
Kazuyoshi Kato, Tsuyoshi Hisa, Maki Matoda, Hidetaka Nomura, Hiroyuki Kanao, Kuniko Utsugi, Nobuhiro Takeshima
BACKGROUND: Though laparoscopic surgery has recently been applied in the treatment of early-stage endometrial cancer, the presence of a large uterus is a hindrance to specimen extraction from the abdominal cavity. We describe a laparoscopic surgical technique for endometrial cancer involving the extraction of the resected specimen through an umbilical zigzag incision. CASE PRESENTATION: A 63-year-old woman with endometrial cancer underwent a total hysterectomy and bilateral salpingo-oophorectomy that was performed laparoscopically...
May 30, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28558811/focal-necrosis-mimicking-breast-cancer-following-coronary-bypass-grafting
#6
Oldřich Coufal, Tomáš Ostřížek, Petr Krsička, Eva Lžičařová, Rudolf Nenutil, Monika Procházková, Beatrix Bencsiková, Peter Grell, Roman Šefr
BACKGROUND: Breast cancer can be diagnosed easily in most cases. However, occasionally, we are faced with some conditions that can mimic it. These may include inflammations, benign tumors, cysts, hematomas, or, more rarely, focal necrosis. CASE PRESENTATION: This report presents a case of focal breast necrosis following myocardial revascularization with the left internal mammary artery, which is a very rare condition, with only few cases described in the literature...
May 30, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28558780/low-grade-fibromyxoid-sarcoma-of-the-external-anal-sphincter-a-case-report
#7
Lee-Kiat Ban, Ailun Heather Tseng, Shih-Hung Huang, Henry Hsin-Chung Lee
BACKGROUND: Low-grade fibromyxoid sarcoma (LGFMS) is a rare soft tissue tumor that has a tendency to grow in the deep soft tissue of the trunk and extremities. Despite its benign appearance, the tumor has a high recurrence rate and metastatic potential. LGFMS in the perineal space is rare, and only a few cases have been reported. We present the first case of LGFMS to be located at the external anal sphincter. CASE PRESENTATION: A 27-year-old male patient admitted to our Surgical Department with perianal pain and swollen for a year...
May 30, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28558772/predictive-value-of-preoperative-peripheral-blood-neutrophil-lymphocyte-ratio-for-lymph-node-metastasis-in-patients-of-resectable-pancreatic-neuroendocrine-tumors-a-nomogram-based-study
#8
Zhou Tong, Lulu Liu, Yi Zheng, Weiqin Jiang, Peng Zhao, Weijia Fang, Weilin Wang
BACKGROUND: Neutrophil-to-lymphocyte ratio (NLR) is one of the systemic inflammation markers, which has prognostic values in many types of tumor. However, hardly any research has reported the relationship between NLR and pancreatic neuroendocrine tumors (PanNETs). In this study, we aimed to evaluate the predictive value of the preoperative peripheral blood NLR on the clinical outcomes in patients of resectable PanNETs. METHODS: Ninety-five cases of PanNETs registered in the First Affiliated Hospital of Zhejiang University between March 2009 and May 2016 and underwent pancreatic surgery were included in this study...
May 30, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28545537/efficacy-of-prophylactic-splenectomy-for-proximal-advanced-gastric-cancer-invading-greater-curvature
#9
Yu Ohkura, Shusuke Haruta, Junichi Shindoh, Tsuyoshi Tanaka, Masaki Ueno, Harushi Udagawa
BACKGROUND: For proximal gastric cancer invading the greater curvature, concomitant splenectomy is frequently performed to secure the clearance of lymph node metastases. However, prognostic impact of prophylactic splenectomy remains unclear. The aim of this study was to clarify the oncological significance of prophylactic splenectomy for advanced proximal gastric cancer invading the greater curvature. METHODS: Retrospective review of 108 patients who underwent total or subtotal gastrectomy for advanced proximal gastric cancer involving the greater curvature was performed...
May 25, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28545454/combining-serum-mirnas-cea-and-cyfra21-1-with-imaging-and-clinical-features-to-distinguish-benign-and-malignant-pulmonary-nodules-a-pilot-study-xianfeng-li-et-al-combining-biomarker-imaging-and-clinical-features-to-distinguish-pulmonary-nodules
#10
Xianfeng Li, Qinghua Zhang, Xiayun Jin, Lihua Cao
BACKGROUND: Our study was designed to improve the accuracy of determining whether pulmonary nodules are benign or malignant. METHODS: We evaluated the clinical and imaging features and serum markers: neuron specific enolase (NSE), carcino-embryonic antigen (CEA), cytokeratin fragment antigen 21-1 (CYFRA 21-1), miRNA-21-5p, and miR-574-5pof in 39 patients with pathology information. Factors that differed significantly between those with benign versus malignant pulmonary nodules were used to establish a prediction model for identifying malignant nodules...
May 25, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28545451/ptk7-is-a-novel-oncogenic-target-for-esophageal-squamous-cell-carcinoma
#11
Kang Liu, Guiqin Song, Xuqian Zhang, Qiujiang Li, Yunxia Zhao, Yuchuan Zhou, Rong Xiong, Xin Hu, Zhirong Tang, Gang Feng
BACKGROUND: Overexpression of PTK7 has been found in multiple cancers and has been proposed to serve as a prognostic marker for intrahepatic cholangiocarcinoma. Its role in esophageal cancer, however, remains to be clarified. We hypothesize that PTK7 positively regulates tumorigenesis of esophageal cancer. METHODS: We examined PTK7 expression pattern in human esophageal squamous carcinoma by Oncomine expression analysis and by immunohistochemistry (IHC) staining...
May 25, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28521842/clinical-and-prognostic-significance-of-hif-1%C3%AE-overexpression-in-oral-squamous-cell-carcinoma-a-meta-analysis
#12
Jianhua Zhou, Shengyun Huang, Lili Wang, Xiao Yuan, Quanjiang Dong, Dongsheng Zhang, Xuxia Wang
BACKGROUND: Recent studies have indicated an association between hypoxia inducible factor-1 alpha (HIF-1α) expression and poor prognosis in patients with oral squamous cell carcinoma (OSCC); however, definitive evidence of this association is yet to be obtained. We performed a meta-analysis to evaluate the association of HIF-1α expression with clinicopathological characteristics and overall survival (OS) of patients with OSCC. METHODS: A literature search for relevant studies published in English language as of February 05, 2016, was performed on PubMed, Web of Science, and EMBASE databases...
May 18, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28511723/feasibility-and-diagnostic-performance-of-dual-tracer-guided-sentinel-lymph-node-biopsy-in-ct1-2n0m0-gastric-cancer-a-systematic-review-and-meta-analysis-of-diagnostic-studies
#13
REVIEW
Ling Huang, Tao Wei, Junjun Chen, Donghui Zhou
BACKGROUND: Dual-tracer-guided sentinel lymph node (SLN) biopsy may provide a promising diagnostic tool to assess accurately the status of lymph node metastasis in the surgical operation and assure the oncologic safety of the function or stomach preserving surgery. The diagnostic performance of this technology in recent studies varied. Thus, we conducted this meta-analysis. METHODS: This systematic review and meta-analysis was registered at the PROSPERO. Eligible studies were searched in the PubMed, EMBASE, Web of Knowledge, and Cochrane Library databases...
May 16, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28506249/an-unusual-case-of-proximal-humeral-simple-bone-cyst-in-an-adult-from-secondary-cystic-change
#14
Mamer S Rosario, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Hiroaki Kimura, Shinji Miwa, Takashi Higuchi, Hiroyuki Inatani, Kensaku Abe, Yuta Taniguchi, Hisaki Aiba, Hiroyuki Tsuchiya
BACKGROUND: Simple bone cysts (SBC) have been documented to occur in adults with closed physeal plates, most commonly affecting the calcaneus in this patient subset. Although most authors theorize an association to trauma, etiology of simple bone cysts remains an enigma up to now. CASE PRESENTATION: A 26-year-old kickboxing coach sought consult for a painful right shoulder which on radiographs and magnetic resonance (MR) imaging showed a proximal humeral lesion with signs of ossification...
May 15, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28494796/a-malignant-solitary-fibrous-tumour-arising-from-the-first-lumbar-vertebra-and-mimicking-an-osteosarcoma-a-case-report
#15
Naoki Oike, Hiroyuki Kawashima, Akira Ogose, Tetsuo Hotta, Toru Hirano, Takashi Ariizumi, Tetsuro Yamagishi, Hajime Umezu, Shoichi Inagawa, Naoto Endo
BACKGROUND: A solitary fibrous tumour (SFT) is an unusual neoplasm typically found in soft tissues. Although SFTs can arise in the bones, they very rarely arise in the vertebral arch. Here, we describe a case of a SFT that arose in the vertebral arch of the first lumbar (L1) spinal vertebrae and mimicked osteosarcoma. CASE PRESENTATION: A 49-year-old woman presented with a 2-month history of lower back pain and a lumbar region mass. Magnetic resonance imaging demonstrated a heterogeneously enhanced mass in the L1 vertebral arch...
May 11, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28494784/influence-of-neoadjuvant-chemotherapy-on-prognosis-of-patients-with-synovial-sarcoma
#16
Yanan Wu, Wenzhi Bi, Gang Han, Jinpeng Jia, Meng Xu
BACKGROUND: This study aimed to explore the clinical efficacy of neoadjuvant chemotherapy combined with surgery in primary synovial sarcoma of the limbs and trunk through retrospective analysis of patients with primary synovial sarcoma of the limbs and trunk treated by this treatment in our hospital. METHODS: A total of 89 patients diagnosed with synovial sarcoma were enrolled in this study between January 2005 and December 2011 in PLA General Hospital. Most of the patients received neoadjuvant chemotherapy combined with operative treatment (84...
May 11, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28490340/morbidity-and-oncologic-outcome-after-saphenous-vein-sparing-inguinal-lymphadenectomy-in-melanoma-patients
#17
Johannes Baur, Katrin Mathe, Anja Gesierich, Gerhard Weyandt, Armin Wiegering, Christoph-Thomas Germer, Martin Gasser, Jörg O W Pelz
BACKGROUND: Inguinal lymph node dissection (LND) is a surgical procedure with a high morbidity rate. Variations in surgical procedure, such as sparing of the saphenous vein, have been proposed to reduce surgical morbidity. While sparing of the saphenous vein has shown promising results in earlier studies, data for this procedure in melanoma patients are rare. In this retrospective study, we report 10-year findings on the effects of saphenous vein-sparing LND on surgical morbidity and oncologic outcomes in melanoma patients...
May 11, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28482928/feasibility-and-safety-of-robot-assisted-thoracic-surgery-for-lung-lobectomy-in-patients-with-non-small-cell-lung-cancer-a-systematic-review-and-meta-analysis
#18
REVIEW
Shiyou Wei, Minghao Chen, Nan Chen, Lunxu Liu
BACKGROUND: The aim of this study is to evaluate the feasibility and safety of robot-assisted thoracic surgery (RATS) lobectomy versus video-assisted thoracic surgery (VATS) for lobectomy in patients with non-small cell lung cancer (NSCLC). METHODS: An electronic search of six electronic databases was performed to identify relevant comparative studies. Meta-analysis was performed by pooling the results of reported incidence of overall morbidity, mortality, prolonged air leak, arrhythmia, and pneumonia between RATS and VATS lobectomy...
May 8, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28472951/low-transverse-incision-for-lateral-neck-dissection-in-patients-with-papillary-thyroid-cancer-improved-cosmesis
#19
Chang Myeon Song, Yong Bae Ji, In Sik Kim, Ji Young Lee, Dong Sun Kim, Kyung Tae
BACKGROUND: Various incisions and approaches have been developed for lateral neck dissection. The purpose of this study was to compare the surgical and cosmetic outcomes of a single low transverse incision with the hockey stick incision for lateral neck dissection (LND) in patients with papillary thyroid carcinoma (PTC). METHODS: We retrospectively analyzed 97 patients with PTC who underwent therapeutic LND and total thyroidectomy by low transverse incision (62 patients) or hockey stick incision (35 patients)...
May 4, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28468632/erratum-to-carbon-ion-radiotherapy-for-desmoid-tumor-of-the-abdominal-wall-a-case-report
#20
Takuya Nagata, Yusuke Demizu, Tomoyuki Okumura, Shinichi Sekine, Naoki Hashimoto, Nobukazu Fuwa, Tomoaki Okimoto, Yutaka Shimada
No abstract text is available yet for this article.
May 3, 2017: World Journal of Surgical Oncology
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