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World Journal of Surgical Oncology

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https://www.readbyqxmd.com/read/28716145/mortality-differences-by-surgical-volume-among-patients-with-stomach-cancer-a-threshold-for-a-favorable-volume-outcome-relationship
#1
Hyeok Choi, Seong-Yoon Yang, Hee-Seung Cho, Woorim Kim, Eun-Cheol Park, Kyu-Tae Han
BACKGROUND: Many studies have assessed the volume-outcome relationship in cancer patients, but most focused on better outcomes in higher volume groups rather than identifying a specific threshold that could assist in clinical decision-making for achieving the best outcomes. The current study suggests an optimal volume for achieving good outcome, as an extension of previous studies on the volume-outcome relationship in stomach cancer patients. METHODS: We used National Health Insurance Service (NHIS) Sampling Cohort data during 2004-2013, comprising healthcare claims for 2550 patients with newly diagnosed stomach cancer...
July 17, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28716127/influence-of-tumor-extent-on-central-lymph-node-metastasis-in-solitary-papillary-thyroid-microcarcinomas-a-retrospective-study-of-1092-patients
#2
Xingjie Yin, Chunping Liu, Yawen Guo, Xiaoyu Li, Na Shen, Xiangwang Zhao, Pan Yu, Shan Wang, Zeming Liu
BACKGROUND: The morbidity of papillary thyroid microcarcinomas is increasing worldwide. Surgery is the main treatment for papillary thyroid microcarcinomas, and the choice of surgical method partly depends on the T stage of the tumor. However, according to the American Joint Commission on Cancer staging system (7th edition), the T stage of papillary thyroid microcarcinomas with different tumor extent is unclear. We aimed to study the effect of tumor extent and other factors on central lymph node metastasis to explore the relationship between tumor extent and T stage and to identify the risk factors predicting central lymph node metastasis in papillary thyroid microcarcinomas...
July 17, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28716043/evolution-in-the-surgical-management-of-gastric-cancer-is-extended-lymph-node-dissection-back-in-vogue-in-the-usa
#3
REVIEW
Tianxiang Chen, Dongsheng Yan, Zhiqiang Zheng, Jiayi Yang, Xiang Da Eric Dong
BACKGROUND: Gastric cancer remains a formidable treatment challenge. For decades, treatment consisted mostly of surgical intervention for this deadly disease. With improvements in the multi-disciplinary management of solid organ malignancies, the approach to this disease is being stepwise refined. MAIN BODY: One of the prevalent controversies in the surgical management of gastric cancer rests on the need for adequate harvesting of lymph nodes. For decades, lymph node dissection is regarded as a staging technique useful in only upstaging the disease...
July 17, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28716033/current-status-of-tertiary-debulking-surgery-and-prognosis-after-secondary-debulking-surgery-for-recurrent-m%C3%A3-llerian-epithelial-cancer-in-japan-a-retrospective-analysis-of-164-patients-kcog-g1402
#4
Tomoko Hirakawa, Takeo Minaguchi, Yoshio Itani, Yuka Kasamatsu, Saki Murase, Shoko Sakurada, Hiroaki Nagano, Kazuhiro Takehara, Tomohiko Tsuruta, Atsushi Arakawa, Kouichiro Kawano, Hiroshi Tsubamoto, Takashi Ushiwaka, Taisuke Mori, Kana Iwai, Motoaki Saito, Hiroyuki Morisawa, Fumitaka Saito, Kenta Yoshida, Masanori Kaneuchi, Hiroki Sato, Kimihiko Ito, Kaei Nasu
BACKGROUND: This study aimed to evaluate the current status of secondary debulking surgery (SDS) and tertiary debulking surgery (TDS; performed for recurrence after SDS) and to assess the overall survival after recurrence of Müllerian epithelial cancer in Japan. We also evaluated the data of patients who underwent a fourth debulking surgery (i.e., quaternary debulking surgery (QDS)). METHODS: We conducted a retrospective study of 164 patients with recurrent Müllerian epithelial cancers (i...
July 17, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28716031/a-rare-case-of-intradural-and-extramedullary-epidermoid-cyst-after-repetitive-epidural-anesthesia-case-report-and-review-of-the-literature
#5
Haruki Funao, Norihiro Isogai, Kenshi Daimon, Yuichiro Mima, Hitoshi Sugiura, Takahiro Koyanagi, Masaya Nakamura, Morio Matsumoto, Ken Ishii
BACKGROUND: Spinal epidermoid cysts are benign tumors, which are rarely seen as an intradural extramedullary spinal cord tumor in the conus medullaris region. Acquired spinal epidermoid cysts are mostly caused by iatrogenic procedures, such as lumbar puncture, and the majority of acquired spinal epidermoid cysts have been reported below the L1 level, because lumbar puncture is usually performed around the iliac crest. Here, we report an extremely rare case of an epidermoid cyst that occurred as an intradural and extramedullary spinal cord tumor attached to the conus medullaris after repetitive epidural anesthesia...
July 17, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28709454/comparison-of-skin-sparing-mastectomy-using-ligasure%C3%A2-small-jaw-and-electrocautery
#6
Young Woo Chang, Hwan Soo Kim, Seung Pil Jung, Sang Uk Woo, Jae Bok Lee, Jeoung Won Bae, Gil Soo Son
BACKGROUND: Skin-sparing mastectomy (SSM) is increasingly used in patients with breast cancer. We compared the differences between use of electrocautery and LigaSure™ Small Jaw in patients with breast cancer who underwent SSM. METHODS: Between January 2012 and December 2015, 81 patients with breast cancer who underwent SSM were selected and were divided into the electrocautery group and the LigaSure™ Small Jaw group based on the devices that were used. Clinicopathological characteristics, body mass index, operative time, and weight of removed breast were obtained from medical records...
July 14, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28709438/surgical-treatment-for-mediastinal-abscess-induced-by-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-a-case-report-and-literature-review
#7
Yujiro Yokoyama, Takahiro Nakagomi, Daichi Shikata, Rumi Higuchi, Toshio Oyama, Taichiro Goto
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a useful and less invasive procedure for the definitive diagnosis of mediastinal and hilar lymph nodes. However, infectious complications can occur after EBUS-TBNA, although they are extremely rare. CASE PRESENTATION: A 66-year-old man with necrotic and swollen lower paratracheal lymph nodes underwent EBUS-TBNA. A mediastinal abscess developed 9 days post-procedure. Surgical drainage and debridement of the abscess were performed along with lymph node biopsy followed by daily washing of the thoracic cavity...
July 14, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28705168/relevance-of-breast-mri-in-determining-the-size-and-focality-of-invasive-breast-cancer-treated-by-mastectomy-a-prospective-study
#8
Anne-Julie Carin, Sébastien Molière, Victor Gabriele, Massimo Lodi, Nicolas Thiébaut, Karl Neuberger, Carole Mathelin
BACKGROUND: The aim of this study was the evaluation of breast MRI in determining the size and focality of invasive non-metastatic breast cancers. METHODS: The prospective, single-centre study conducted in 2015 compared preoperative MRI with histological analysis of mastectomy. RESULTS: One hundred one mastectomies from 98 patients were extensively analysed. The rates of false-positive and false-negative MRI were 2 and 4% respectively. The sensitivity of breast MRI was 84...
July 14, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28693505/effects-of-radiofrequency-ablation-versus-other-ablating-techniques-on-hepatocellular-carcinomas-a-systematic-review-and-meta-analysis
#9
Wen Luo, Yunfei Zhang, Guangbin He, Ming Yu, Minjuan Zheng, Liwen Liu, Xiaodong Zhou
BACKGROUND: Percutaneous ablation has quickly arisen as one of the important alternative treatments for hepatocellular carcinoma (HCC). We aimed to compare the therapeutic effects of radiofrequency ablation (RFA) and other ablative techniques on HCCs. METHODS: Databases were searched to identify literature on complete tumor ablation (CTA), overall survival (OS), local tumor recurrence (LTR), and complications of RFA in the treatment of HCC, compared with those of microwave ablation (MWA), percutaneous ethanol injection (PEI), PEI plus RFA, cryoablation (CRA), laser ablation (LSA), and high-intensity focused ultrasound...
July 10, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28693494/variation-of-sentinel-lymphatic-channels-slcs-and-sentinel-lymph-nodes-slns-assessed-by-contrast-enhanced-ultrasound-ceus-in-breast-cancer-patients
#10
Ying Wang, Wenbin Zhou, Cuiying Li, Haiyan Gong, Chunlian Li, Nianzhao Yang, Xiaoming Zha, Lin Chen, Tiansong Xia, Xiaoan Liu, Minghai Wang, Qiang Ding
BACKGROUND: The objective of this study was to assess the feasibility of detecting the variation of sentinel lymphatic channels (SLCs) and sentinel lymph nodes (SLNs) in breast cancer patients using contrast-enhanced ultrasound (CEUS). METHODS: A total of 46 breast cancer patients were prospectively recruited in the study. All the participants received intradermal and peritumoral injection of microbubbles as contrast agent, and SLCs and SLNs were assessed preoperatively...
July 10, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28683751/a-novel-transurethral-resection-technique-for-superficial-bladder-tumor-retrograde-en-bloc-resection
#11
Kai-Yan Zhang, Jin-Chun Xing, Wei Li, Zhun Wu, Bin Chen, Dong-Yu Bai
BACKGROUND: Transurethral resection of bladder tumor (TURBT) is the standard approach to bladder tumors but suffers from several disadvantages. The aim of this study was to evaluate the safety and efficacy of a novel procedure of retrograde en bloc resection of bladder tumor (RERBT) with conventional monopolar resection electrode for the treatment of superficial bladder tumors. METHODS: RERBT and conventional TURBT (C-TURBT) were conducted, respectively, in 40 and 50 patients diagnosed with superficial papillary bladder tumors...
July 6, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28679451/the-significance-of-a-nineteenth-century-definition-in-the-era-of-genomics-linitis-plastica
#12
REVIEW
Annamaria Agnes, Jeannelyn S Estrella, Brian Badgwell
BACKGROUND: Linitis plastica due to gastric adenocarcinoma is a condition with a long history, but still lacks a standardized definition and is commonly confused with Borrmann type IV, Lauren diffuse, and signet-cell type gastric cancer. The absence of a clear definition is a problem when investigating its biological characteristics and role as a possible independent factor for prognosis. Nevertheless, the biological behavior for linitis plastica, which is unique, may be valuable in risk stratification and have implications for treatment...
July 5, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28679433/long-term-survival-of-hepatocellular-carcinoma-after-percutaneous-radiofrequency-ablation-guided-by-ultrasound
#13
Weimin Zhang, Erping Luo, Jianhe Gan, Xiaomin Song, Zuowei Bao, Huiping Zhang, Minhua Chen
BACKGROUND: The risk factors for recurrence and death after radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) remain poorly known. This study was aimed to study the 10-year overall survival (OS) of HCC treated by ultrasound (US)-guided RFA and the risk factors for recurrence and death. METHODS: Between June 2005 and June 2016, 1000 patients with HCC treated by US-guided RFA at 4 hospitals in China; among them, 525 patients met the criteria for radical ablation and 410 had high AFP levels before RFA treatment...
July 5, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28679405/colonic-metastasis-from-breast-carcinoma-a-case-report
#14
Kazuma Tsujimura, Tsuyoshi Teruya, Masaya Kiyuna, Kuniki Higa, Junko Higa, Kouji Iha, Kiyoshi Chinen, Masaya Asato, Yasukatsu Takushi, Morihito Ota, Eijirou Dakeshita, Atsushi Nakachi, Akira Gakiya, Hiroshi Shiroma
BACKGROUND: Colonic metastasis from breast carcinoma is very rare. Here, we report a case of colonic metastasis from breast carcinoma. CASE PRESENTATION: The patient was a 51-year-old woman. She had upper abdominal pain, vomiting, and diarrhea, repeatedly. We performed abdominal contrast-enhanced computed tomography (CT) to investigate these symptoms. The CT scan revealed a tumor in the ascending colon with contrast enhancement and showed an expanded small intestine...
July 5, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28676072/giant-desmoplastic-cutaneous-squamous-cell-carcinoma-of-the-gluteal-region
#15
Darko Katalinic, Antonio Juretic
Cutaneous squamous cell carcinoma (cSCC) is the most common type of skin tumour with the ability of metastatic spread. It represents about 20% of all malignancies diagnosed worldwide each year. Despite increased knowledge regarding the causes of skin cancer, the incidence of cSCC rises. The disease originates from epidermal keratinocytes, but it may occur on all areas of the body. It has an invasive nature and the potential to metastasise. We report unusual case of a giant metastatic desmoplastic cSCC of the gluteal region in a patient with previously resected desmoplastic cSCC presenting 8 months later with multiple liver and lung metastases...
July 4, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28673327/special-role-of-jun-in-papillary-thyroid-carcinoma-based-on-bioinformatics-analysis
#16
Wenzheng Chen, Qingfeng Liu, Yunxia Lv, Debin Xu, Wanzhi Chen, Jichun Yu
BACKGROUND: Papillary thyroid carcinoma (PTC) is the most common malignancy in thyroid tissue, and the number of patients with PTC has been increasing in recent years. Discovering the mechanism of PTC genesis and progression and finding new potential diagnostic biomarkers/therapeutic target genes of PTC are of great significance. METHODS: In this work, the datasets GSE3467 and GSE3678 were downloaded from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) were identified with the limma package in R...
July 3, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28673297/risk-factors-of-liver-metastasis-from-advanced-pancreatic-adenocarcinoma-a-large-multicenter-cohort-study
#17
Dong S, Wang L, Guo Y B, Ying H F, Shen X H, Meng Z Q, Chen Hao, Chen Q W, Li Z S
BACKGROUND: Clinical prognostic parameters of liver metastasis from pancreatic adenocarcinoma have not been specifically identified.This study is to explore the risk factors of liver metastasis in advanced pancreatic adenocarcinoma (PDAC) patients in China. METHODS: A multicenter cohort study was conducted to explore whether liver metastasis in locally advanced and metastatic PDAC could be reflected by some common laboratory indexes. We collected 1787 advanced PDAC patients from three participating hospitals between 2004 and 2014...
July 3, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28673296/better-survival-after-breast-conserving-therapy-compared-to-mastectomy-when-axillary-node-status-is-positive-in-early-stage-breast-cancer-a-registry-based-follow-up-study-of-6387-norwegian-women-participating-in-screening-primarily-operated-between-1998-and
#18
Olaf Johan Hartmann-Johnsen, Rolf Kåresen, Ellen Schlichting, Jan F Nygård
BACKGROUND: Recent registry studies on early-stage breast cancer have shown better survival rates when women underwent breast-conserving therapy (BCT) compared with mastectomy (MTX). The aim of this study is to investigate women participating in screening, in all four stages of early breast cancer (T1N0M0, T2N0M0, T1N1M0, and T2N1M0), as to whether there is a survival benefit when women undergo BCT compared to MTX. METHOD: A cohort of 6387 women aged 50-69, with primary-operated breast cancer from January 1998 to December 2009, participating in screening and followed-up until the end of 2010...
July 3, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28662703/the-diagnosis-of-a-metastatic-breast-tumor-from-ovarian-cancer-by-the-succession-of-a-p53-mutation-a-case-report
#19
Ryutaro Mori, Manabu Futamura, Kasumi Morimitsu, Chiemi Saigo, Tatsuhiko Miyazaki, Kazuhiro Yoshida
BACKGROUND: Metastatic breast tumors from other organs are very rare. We herein describe the case of a patient with a metastatic breast tumor due to ovarian cancer who was diagnosed by the succession of a p53 mutation. CASE PRESENTATION: The patient was a 59-year-old woman with sigmoid colon stenosis. Diagnostic imaging revealed a pelvic mass, multiple liver tumors, ascites, and multiple swollen para-aortic lymph nodes, suggesting an advanced ovarian tumor. Transverse loop colostomy and partial resection of the greater omentum was performed followed by six cycles of paclitaxel with carboplatin chemotherapy (TC therapy)...
June 29, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28651545/mismatch-repair-deficiency-screening-in-colorectal-carcinoma-by-a-four-antibody-immunohistochemical-panel-in-pakistani-population-and-its-correlation-with-histopathological-parameters
#20
Atif Ali Hashmi, Rabia Ali, Zubaida Fida Hussain, Naveen Faridi, Erum Yousuf Khan, Syed Muhammad Abu Bakar, Muhammad Muzzammil Edhi, Mehmood Khan
BACKGROUND: Microsatellite instability (MSI) operates as the second major pathway in the colorectal carcinogenesis. Although genetic testing remains the gold standard for the detection of MSI, the College of American Pathologists (CAP) recommends an initial immunohistochemical workup with a four-antibody panel (MLH1, PMS2, MSH2, and MSH6) to screen for a defective mismatch repair system. An increased trend towards young age colorectal carcinoma (CRC) has been noticed in our population over recent years; however, neither screening for MSI by immunohistochemistry (IHC)/genetic testing was done nor were its morphological features studied...
June 26, 2017: World Journal of Surgical Oncology
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