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World Journal of Surgical Oncology

Ali Ramouz, Seyed Ziaeddin Rasihashemi, Abdolrasoul Safaeiyan, Mahdie Hosseini
BACKGROUND: LigaSure® Small Jaw (LSJ) has been recently introduced as an energy-based vessel sealing device, which has provided better intraoperative and postoperative outcomes in thyroidectomies, compared to conventional technique. In the current study, we aimed to examine the efficiency of hand-sewn and LSJ thyroidectomy, based on operation time and perioperative complications. METHODS: All patients with the diagnosis of multinodular goiter, thyroid cancers, retrosternal goiter and other indications for thyroid surgeries, enrolled...
September 21, 2018: World Journal of Surgical Oncology
Jacob Engellau, Leanne Seeger, Robert Grimer, Robert Henshaw, Hans Gelderblom, Edwin Choy, Sant Chawla, Peter Reichardt, Michael O'Neal, Amy Feng, Ira Jacobs, Zachary J Roberts, Ada Braun, Bruce A Bach
BACKGROUND: Denosumab has been shown to reduce tumor size and progression, reform mineralized bone, and increase intralesional bone density in patients with giant cell tumor of bone (GCTB); however, radiologic assessment of tumors in bone is challenging. The study objective was to assess tumor response to denosumab using three different imaging parameters in a prespecified analysis in patients with GCTB from two phase 2 studies. METHODS: The studies enrolled adults and adolescents (skeletally mature and at least 12 years of age) with radiographically measurable GCTB that were given denosumab 120 mg every 4 weeks, with additional doses on days 8 and 15 of cycle 1...
September 19, 2018: World Journal of Surgical Oncology
Junhai Pan, Xiaolong Ge, Wei Zhou, Xin Zhong, Lihu Gu, Hepan Zhu, Xinlong Li, Weilin Qi, Xianfa Wang
BACKGROUND: Postoperative complications, especially postoperative pancreatic fistulas, remain the major concern following pancreaticoduodenectomy (PD). Mesh-reinforced pancreatic anastomoses, including pancreatojejunostomy (PJ) and pancreatogastrostomy (PG), are a new effective technique in PD. This study was conducted to analyze the safety and efficacy of this new technique and to compare the results of mesh-reinforced PJ vs PG. METHODS: A total of 110 patients who underwent PD between August 2005 and January 2016 were eligible in this study...
September 17, 2018: World Journal of Surgical Oncology
Nan Zhang, Qian Fei, Jiajia Gu, Li Yin, Xia He
BACKGROUND: Gastric carcinoma, a highly common malignant tumor, is treated mainly by surgery. Meanwhile, radiotherapy is attracting increased attention as a crucial locoregional therapy. However, the application of radiotherapy in gastric carcinoma is still limited and radiation standards remain debatable. MAIN BODY: The use of preoperative radiotherapy for treating gastroesophageal junction cancer has advanced. However, additional phase III clinical trials are needed to further verify the therapeutic value of preoperative radiotherapy for gastric cancer...
September 13, 2018: World Journal of Surgical Oncology
Jun Kurihara, Satoshi Yokoo, Miku Ichikawa, Takahiro Shimizu, Masaru Ogawa, Mai Seki
BACKGROUND: Perineurioma (PN) is a peripheral nerve disease that primarily develops in the limbs and trunk and very rarely occurs in the oral cavity. PN is classified into two types: intraneural perineurioma (INPN) and soft tissue perineurioma (extraneural perineurioma, ENPN). In this article, we report a patient with mandibular body INPN derived from the perineurium of the inferior alveolar nerve. CASE PRESENTATION: The patient was a 43-year-old male. He consulted our department for a detailed examination of the right mandibular body...
September 13, 2018: World Journal of Surgical Oncology
Takayuki Ogino, Masaki Okuyama, Tomoki Hata, Junji Kawada, Miho Okano, Yongkook Kim, Toshimasa Tsujinaka
Adequate blood flow in anastomosis is of paramount importance to prevent anastomotic leakage. However, it is sometimes difficult to predict the viability of the intestine during surgery. During left-sided colectomy, blood flow on the remnant distal bowel is supplied only from the middle and inferior rectal arteries. The blood backflow after the root ligation of the inferior mesenteric artery is often said to be kept up to promontorium levels; however, this premise is actually based on experience, without reliable evidence...
September 13, 2018: World Journal of Surgical Oncology
Savino Occhionorelli, Dario Andreotti, Pierpaola Vallese, Lucia Morganti, Domenico Lacavalla, Elena Forini, Giovanni Pascale
BACKGROUND: Lymph node involvement is one of the most important prognostic factors in colon cancer. Twelve is considered the minimum number of lymph nodes necessary to retain reliable tumour staging, but several factors can potentially influence the lymph node harvesting. Emergent surgery for complicated colon cancer (perforation, occlusion, bleeding) could represent an obstacle to reach the benchmark of 12 nodes with an accurate lymphadenectomy. So, an efficient classification system of lymphatic involvement is crucial to define the prognosis, the indication to adjuvant therapy and the follow-up...
September 13, 2018: World Journal of Surgical Oncology
Majid Akrami, Peyman Arasteh, Tannaz Eghbali, Hadi Raeisi Shahraki, Sedigheh Tahmasebi, Vahid Zangouri, Abbas Rezaianzadeh, Abdolrasoul Talei
BACKGROUND: In here, we constructed personalized models for predicting breast cancer (BC) recurrence according to timing of recurrence (as early and late recurrence). METHODS: An efficient algorithm called group LASSO was used for simultaneous variable selection and risk factor prediction in a logistic regression model. RESULTS: For recurrence < 5 years, age (OR 0.96, 95% CI = 0.95-0.97), number of pregnancies (OR 0.94, 95% CI = 0...
September 12, 2018: World Journal of Surgical Oncology
Natasa Colakovic, Darko Zdravkovic, Zlatko Skuric, Davor Mrda, Jasna Gacic, Nebojsa Ivanovic
BACKGROUND: The utilization of intraoperative ultrasound (IOUS) in breast cancer surgery is a relatively new concept in surgical oncology. Over the last few decades, the field of breast cancer surgery has been striving for a more rational approach, directing its efforts towards removing the tumor entirely yet sparing tissue and structures not infiltrated by tumor cells. Further progress in objectivity and optimization of breast cancer excision is possible if we make the tumor and surrounding tissue visible and measurable in real time, during the course of the operation; IOUS seems to be the optimal solution to this complex requirement...
September 11, 2018: World Journal of Surgical Oncology
Minxun Lu, Jie Wang, Cong Xiao, Fan Tang, Li Min, Yong Zhou, Wenli Zhang, Chongqi Tu
BACKGROUND: Uncemented endoprosthetic knee replacement has become a mainstream treatment for malignant tumours of the distal femur. Most femoral stems, however, are straight and therefore poorly fit the anteriorly bowed curvature of the femur. To address this issue, we used a short, curved, uncemented press-fit femoral stem and evaluated its short-term outcomes after reconstruction of the distal femur. METHODS: Forty-two patients underwent distal femur replacement using curved press-fit stem...
September 10, 2018: World Journal of Surgical Oncology
Lihong Cao
BACKGROUND: Potential risk of thyroid cancer in patients with inflammatory bowel disease has not been well investigated. The aim of the study was to reveal the relationship between history of inflammatory bowel disease and risk of thyroid cancer. METHODS: First, 1392 patients with inflammatory bowel disease and 1392 controls were included in a case-control study. All patients did not receive immunosuppressive therapy. A multivariate logistic regression analysis was adopted to determine the relationship between history of inflammatory bowel disease and risk of thyroid cancer...
September 10, 2018: World Journal of Surgical Oncology
Maurizio Zizzo, Lara Ugoletti, Andrea Morini, Antonio Manenti, Filippo Lococo, Claudio Pedrazzoli
In a previous issue of the Journal, Zhong et al. reported a retrospective study that compared the perioperative outcomes of the mesh-reinforced pancreaticojejunostomy with conventional pancreaticojejunostomy. They concluded that mesh-reinforced pancreaticojejunostomy was a safe and effective technique, as it provided a safe anchor site for suture, thus reducing the risk of pancreatic leakage. Considering these encouraging results, we present a further simple technique using ligamentum teres hepatis wrap around pancreatojejunostomy for prevention of postoperative pancreatic fistula after pancreaticoduodenectomy...
September 7, 2018: World Journal of Surgical Oncology
Chun-Ping Ning, Xiaoli Ji, Hong-Qiao Wang, Xiao-Ying Du, Hai-Tao Niu, Shi-Bao Fang
BACKGROUND: To validate the clinical value of simple rules in distinguishing malignant adnexal masses from benign ones and to explore the effect of simple rules for experienced and less-experienced sonographers. METHODS: Patients with persistent adnexal masses were enrolled between November 2013 and December 2015. All masses were proven through histological examinations. Five sets of diagnoses were made and compared with one another. Diagnosis 1 was made, according to the simple rules, by a trainee with little clinical diagnostic experience...
September 5, 2018: World Journal of Surgical Oncology
Ebbe Billmann Thorgersen, Espen Melum, Trine Folseraas, Stein Gunnar Larsen, Pål Dag Line
BACKGROUND: Diagnostic work-ups in transplanted immunosuppressed patients are a challenge as non-specific findings may be interpreted as transplant-related complications. If the disease in question is rare and slowly developing like pseudomyxoma peritonei (PMP), it is even more difficult. Cytoreductive surgery (CRS) and subsequent hyperthermic intraperitoneal chemotherapy (HIPEC) is the recommended treatment for PMP even with extensive peritoneal spread. CRS-HIPEC for PMP after liver transplantation (LTX) has not been described before...
September 5, 2018: World Journal of Surgical Oncology
Chen Huang, Xunyu Xu, Qianshun Chen, Shengmei Lin
BACKGROUND: It is a very rare condition for a patient to have right lung cancer and a right-sided aortic arch simultaneously. Right lobectomy under video-assisted thoracoscopic surgery (VATS) in such a patient is a challenging procedure that is seldom reported. We successfully performed a VATS right upper lobectomy in a 77-year-old female with a right-sided aortic arch and Kommerell diverticulum. CASE PRESENTATION: A 77-year-old woman was referred to our division for a mixed ground-glass opacity lesion in the right upper lung...
August 30, 2018: World Journal of Surgical Oncology
Pauline Duconseil, Ugo Marchese, Jacques Ewald, Marc Giovannini, Djamel Mokart, Jean-Robert Delpero, Olivier Turrini
BACKGROUND: To determine predictive factors of postoperative pancreatic fistula (POPF) in patients undergoing enucleation (EN). METHODS: From 2005 to 2017, 47 patients underwent EN and had magnetic resonance imaging available for precise analysis of tumor location. Three pancreatic zones were delimited by the right side of the portal vein and the main pancreatic head duct (zone #3 comprising the lower head parenchyma and the uncinate process). RESULTS: The mortality and morbidity rates were 0% and 62%, respectively...
August 29, 2018: World Journal of Surgical Oncology
Minglei Yang, Nanzhe Zhong, Chenglong Zhao, Wei Xu, Shaohui He, Jian Zhao, Xinghai Yang, Jianru Xiao
BACKGROUND: Synovial sarcoma (SS) is a soft tissue sarcoma that rarely occurs in the spine, and a minimal number of cases have been reported in the literature. Spinal SS is challenging in diagnosis and treatment and has a poor prognosis. The aim of this study was to summarize and analyse the clinical features and outcomes of patients with spinal SS. METHODS: A total of 16 cases of patients with spinal SS admitted to our institution were reviewed retrospectively...
August 27, 2018: World Journal of Surgical Oncology
Aris I Giotakis, Claus Pototschnig
BACKGROUND: Post-radiotherapy laryngeal edema may affect the patients' quality of life, leading to repeated treatment attempts, which include massage/physical therapy, inhalations, and/or tracheostomy. CASE PRESENTATION: We report the surgical treatment approach of a 69-year-old patient with severe persistent post-radiotherapy laryngeal edema. After multiple inpatient admissions and failed conservative therapy, we used the erbium laser to treat the arytenoid edema...
August 27, 2018: World Journal of Surgical Oncology
Chaoran Yu, Pei Xue, Luyang Zhang, Ruijun Pan, Zhenhao Cai, Zirui He, Jing Sun, Minhua Zheng
BACKGROUND: Trastuzumab has been prevailingly accepted as a beneficial treatment for gastric cancer (GC) by targeting human epidermal growth factor receptor 2 (HER2)-positive. However, the therapeutic resistance of trastuzumab remains a major obstacle, restricting the therapeutic efficacy. Therefore, identifying potential key genes and pathways is crucial to maximize the overall clinical benefits. METHODS: The gene expression profile GSE77346 was retrieved to identify the differentially expressed genes (DEGs) associated with the trastuzumab resistance in GC...
August 22, 2018: World Journal of Surgical Oncology
Xiaobin Yuan, Bin Zhang, Caoyang Hu, Xuhui Zhang, Dongwen Wang
BACKGROUND: Situs inversus totalis is a relatively rare congenital anomaly. Performing the retrolaparoscopic adrenalectomy for the patient with situs inversus totalis is a skill-demanding and challenging surgical task, which has been even more rarely reported. CASE PRESENTATION: We present a case with a large right adrenal mass (10.2 × 9.4 × 7.9 cm) complicated by situs inversus totalis. This 59-year-old female patient underwent the retrolaparoscopic adrenalectomy in our department...
August 20, 2018: World Journal of Surgical Oncology
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