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World Journal of Surgical Oncology

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https://www.readbyqxmd.com/read/29145864/intraductal-tubulopapillary-neoplasm-itpn-of-the-pancreas-associated-with-an-invasive-component-a-case-report-with-review-of-the-literature
#1
Stefanie Kuscher, Hartmut Steinle, Afschin Soleiman, Dietmar Öfner, Stefan Schneeberger, Georg Oberhuber
BACKGROUND: Intraductal tubulopapillary neoplasm (ITPN) depicts a distinct entity in the subgroup of premalignant epithelial tumors of the pancreas. Although the histomorphological and immunophenotypical characterization of ITPN has been described by several authors in terms of report of case series in the past, the rarity of that tumor subtype and similarity to other entities still makes identification of ITPN a challenge for radiologists and pathologists. To date, little is known about tubulopapillary carcinoma that can evolve from ITPN...
November 16, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29132434/an-acetabular-preserving-procedure-for-pelvic-giant-cell-tumor-involving-partial-acetabulum
#2
Cong Xiao, Yong Zhou, Wenli Zhang, Yi Luo, Chongqi Tu
BACKGROUND: The management of pelvic giant cell tumors (GCTs) involving the acetabulum remains a challenge for surgeons on how to balance the relative benefits of minimizing recurrence and maintaining postoperative hip function. The present study was to present and evaluate the clinical indications, operative technique, and outcomes of pelvic GCTs involving partial acetabulum treated with multiplanar osteotomy and reconstruction of autogenous femoral head bone grafts combined with cementless total hip arthroplasty (THA)...
November 13, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29132392/false-negative-braf-v600e-mutation-results-on-fine-needle-aspiration-cytology-of-papillary-thyroid-carcinoma
#3
Se Hyun Paek, Byung Seup Kim, Kyung Ho Kang, Hee Sung Kim
BACKGROUND: The BRAF V600E mutation is highly specific for papillary thyroid carcinoma (PTC). A test for this mutation can increase the diagnostic accuracy of fine-needle aspiration cytology (FNAC), but a considerably high false-negative rate for the BRAF V600E mutation on FNAC has been reported. In this study, we investigated the risk factors associated with false-negative BRAF V600E mutation results on FNAC. METHODS: BRAF V600E mutation results of 221 PTC nodules between December 2011 and June 2013 were retrospectively reviewed...
November 13, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29132383/an-unusually-large-osteochondroma-of-the-mandibular-angle-a-case-report
#4
Ryosuke Abe, Ikuya Miyamoto, Hirotaka Sato, Daishi Saitou, Genki Yamaya, Hiroyuki Yamada
BACKGROUND: Osteochondroma is a benign bone tumor that can occur in both the mesenchymal and craniofacial bones. However, craniofacial osteochondromas are extremely rare, because the mandible develops by intramembranous ossification rather than by endochondral ossification. CASE PRESENTATION: The most common site of craniofacial osteochondroma is the mandibular condyle, followed by the coronoid process. In the present study, we have described the case of a 64-year-old Japanese man with an unusually large osteochondroma located on the internal angle of the mandibular body...
November 13, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29121944/first-experience-of-robotic-spleen-preserving-distal-pancreatectomy-in-a-child-with-insulinoma
#5
Ming-Gen Hu, Yuan-Hong Xiao, Dong-Da Song, Guo-Dong Zhao, Yan-Zhe Liu, Zheng Wang, Hao-Yu Li, Rong Liu
BACKGROUND: An insulinoma is a functional neuroendocrine pancreatic tumor, and surgical resection is indicated. Robot-assisted laparoscopic surgeries have been shown to be generally safe and feasible for treatment of pediatric cases of urologic and digestive disease. CASE PRESENTATION: In July 2016, a 9-year-old girl (24 kg, 120 cm) was admitted with a pancreatic tail insulinoma and underwent robot-assisted spleen-preserving laparoscopic distal pancreatectomy...
November 9, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29110716/postoperative-survival-of-egfr-tki-targeted-therapy-in-non-small-cell-lung-cancer-patients-with-egfr-19-or-21-mutations-a-retrospective-study
#6
Wenjing Yang, Yibo Gao, Xuelian Li, Jing Zhang, Tiejun Liu, Xiaoli Feng, Hao Pan, Xiaofan Yang, Shuanghua Xie, Xiaoshuang Feng, Zhangyan Lv, Yonggang Wang, Zhaoli Chen, Jie He
BACKGROUND: The aim of this retrospective study is to identify epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer patients and to compare the long-term postoperative outcomes in different EGFR-TKI-targeted therapy effects between the different EGFR mutation groups. METHODS: A total of 2094 postoperative non-small cell lung cancer (NSCLC) patients with EGFR gene detection were collected in the Department of Pathology in the Cancer Hospital Chinese Academy of Medical Sciences from January 2003 to January 2014...
November 6, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29110671/residual-microcalcifications-after-neoadjuvant-chemotherapy-for-locally-advanced-breast-cancer-comparison-of-the-accuracies-of-mammography-and-mri-in-predicting-pathological-residual-tumor
#7
Yeong Yi An, Sung Hun Kim, Bong Joo Kang
BACKGROUND: The aims of this study were to correlate residual mammographic microcalcifications after neoadjuvant chemotherapy (NAC) with pathological results and to compare the accuracy of mammography (MG) and magnetic resonance imaging (MRI) in predicting the size of residual tumors. METHODS: The imaging findings and pathological results for 29 patients with residual microcalcifications after NAC were reviewed. We compared the agreement of the measured extent of residual microcalcifications based on MG and residual enhancement based on MRI with the residual tumor size based on pathology...
November 6, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29096658/safety-and-efficacy-of-intralesional-steroid-injection-for-aggressive-fibromatosis
#8
Dumnoensun Pruksakorn, Sratwadee Lorsomradee, Areerak Phanphaisarn, Pimpisa Teeyakasem, Jeerawan Klangjorhor, Parunya Chaiyawat, Natapong Kosachunhanun, Jongkolnee Settakorn, Olarn Arpornchayanon
BACKGROUND: Treatment of recurrent aggressive fibromatosis (AF) following surgical resection is a clinical challenge. Non-steroidal anti-inflammatory drugs (NSAIDs) have been reported to be an effective option for controlling the disease. However, long-term NSAID use can result in unfavorable complications. This study was a trial of the use of intralesional steroid injection (ILSI) including investigation of safety margins and clinical outcomes of high-dose steroids for local use treatment of AF...
November 2, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29096656/liver-resection-for-hepatocellular-carcinoma-in-patients-with-hematological-malignancies
#9
Hui-Chen Lin, Yang-Shen Yang, Chieh-Lin Jerry Teng, Ching-Hui Shen, Yee-Gee Jan, Shao-Bin Cheng, Cheng-Chung Wu, Yi-Ling Lin, Chu-Chun Huang, Fang-Ku P'eng
BACKGROUND: Improvements in antimetabolite drugs have prolonged the survival of patient with hematological malignancies. However, these drugs may have hepatotoxic side effects and may induce acute liver failure, chronic liver fibrosis, cirrhosis, or even hepatocellular carcinoma (HCC). Although liver resection remains a curative option for HCC, its role in HCC with hematological malignancies has never been fully explored. METHODS: A retrospective review of 1725 patients who underwent curative liver resection for newly diagnosed HCC between 1994 and 2016 was conducted...
November 2, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29096643/comparison-of-sentinel-lymph-node-biopsy-guided-by-indocyanine-green-blue-dye-and-their-combination-in-breast-cancer-patients-a-prospective-cohort-study
#10
Jiajia Guo, Houpu Yang, Shu Wang, Yingming Cao, Miao Liu, Fei Xie, Peng Liu, Bo Zhou, Fuzhong Tong, Lin Cheng, Hongjun Liu, Siyuan Wang
BACKGROUND: Recent studies show that near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) has the potential to improve the performance of sentinel lymph node (SLN) mapping. The current cohort study was designed to assess the value of the combination of ICG and methylene blue (MB) dye in patients undergoing SLN biopsy. METHODS: A prospective self-controlled trial was designed to detect the difference in the detection efficacies of ICG, MB, and combined ICG and MB (ICG + MB) navigation methods...
November 2, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29096642/positive-surgical-margin-following-radical-nephrectomy-is-an-independent-predictor-of-local-recurrence-and-disease-specific-survival
#11
Yasmin Abu-Ghanem, Jacob Ramon, Raanan Berger, Issac Kaver, Edi Fridman, Raya Leibowitz-Amit, Zohar A Dotan
BACKGROUND: Positive surgical margins (PSM) are recognized as an adverse prognostic sign and are often associated with higher rates of local and systemic disease recurrence. The data regarding the oncological outcome for PSM following radical nephrectomy (RN) is limited. We examined the predictive factors for PSM and its influence on survival and site of recurrence in patients treated with RN for renal cell carcinoma (RCC). METHODS: Clinical, pathologic and follow-up data on 714 patients undergoing RN for kidney cancer were analyzed...
November 2, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29070049/analysis-of-the-causes-of-failure-after-radical-surgery-in-patients-with-pt3n0m0-thoracic-esophageal-squamous-cell-carcinoma-and-consideration-of-postoperative-radiotherapy
#12
Wen-Bin Shen, Hong-Mei Gao, Shu-Chai Zhu, You-Mei Li, Shu-Guang Li, Jin-Rui Xu
BACKGROUND: Five-year overall survival rate of TESCC after surgery is low (approximately 30% to 60%), so it is meaningful to discuss the significance of PORT. METHODS: We retrospectively collected the data of 227 patients with PT3N0M0 esophageal cancer (EC). The failure pattern after surgery was analyzed. Difference of adjuvant PORT in patients with PT3N0M0 TESCC and the appropriate population were explored based on the relevant studies. RESULTS: There were 58 cases with intrathoracic locoregional recurrence (LRR) after radical surgery and 27 cases with distant metastasis, including 10 cases of recurrence...
October 25, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29065879/impact-of-surgical-resection-extension-on-outcome-for-primary-well-differentiated-thyroid-cancer-a-retrospective-analysis
#13
S Muller, M Senne, A Kirschniak, A Königsrainer, R Bares, C Falch
BACKGROUND: The surgical resection extension in well-differentiated thyroid cancer is controversially discussed with the possibility of an overtreatment on the one hand against the risk of local disease recurrence. The aim of this study is to evaluate how the surgical resection extension with the adjunction of radioiodine therapy affects postoperative morbidity and the oncologic outcome of patients primarily treated for well-differentiated thyroid cancer. METHODS: All patients undergoing primary surgery for a well-differentiated, non-recurrent thyroid cancer from January 2005 to April 2013 at Tuebingen University Hospital were retrospectively analyzed...
October 24, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29065877/postoperative-c-reactive-protein-albumin-ratio-as-a-novel-predictor-for-short-term-complications-following-gastrectomy-of-gastric-cancer
#14
Feng Sun, Xiaolong Ge, Zhijian Liu, Shangce Du, Shichao Ai, Wenxian Guan
BACKGROUND: Postoperative complications following gastric cancer resection remain a clinical problem. Early detection of postoperative complications is needed before critical illness develops. The purpose of this study was to evaluate the prognostic value of C-reactive protein/albumin ratio in patients with gastric cancer. METHODS: A total of 322 patients undergoing curative (R0) gastrectomy between 2015 and 2017 were retrospectively analyzed. Univariate and multivariate analyses were performed to identify clinical factors predicting postoperative complications...
October 24, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29052527/negative-genic-switch-of-her-2-in-the-primary-tumor-instead-of-the-synchronous-metastatic-nodal-lesions-after-neoadjuvant-chemotherapy-in-a-patient-with-primary-her2-positive-breast-cancer
#15
Hao-Ran Chen, Yu-Tuan Wu, Qiu-Bo Yu, Ya-Ying Yang, Yu-Xian Wei, Hong-Yuan Li, Kai-Nan Wu, Ling-Quan Kong
BACKGROUND: A few retrospective studies have indicated that neoadjuvant chemotherapy (NAC) in breast cancer may change biomarker profiles of the primary tumor. Little is known about the status of HER-2 gene of the synchronous nodal metastases when that of the residual tumor undergoes negative conversion in a neoadjuvant setting. CASE PRESENTATION: We describe a female patient with left breast cancer (T2N2M0) who underwent negative conversion of HER-2 in the primary tumor instead of the synchronous nodal lesions after NAC...
October 19, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29047391/report-of-a-case-combining%C3%A2-solitary-peutz-jeghers-polyp-colitis-cystica-profunda-and-high-grade-dysplasia-of-the-epithelium%C3%A2-of-the-colon
#16
Alexandros Papalampros, Michail G Vailas, Maria Sotiropoulou, Efstratia Baili, Spiridon Davakis, Demetrios Moris, Evangelos Felekouras, Ioanna Deladetsima
BACKGROUND: Colitis cystica profunda is a rare nonneoplastic disease defined by the presence of intramural cysts that contain mucus, usually situated in the rectosigmoid area, which can mimic various malignant lesions and polyps. Its etiology still remains not fully elucidated, and several mechanisms such as congenital, post-traumatic, and infectious have been implicated in the development of this rare entity. CASE PRESENTATION: Herein, we describe a unique case of colitis cystica profunda in the setting of Peutz-Jeghers-type polyp of the sigmoid colon, associated with high-grade dysplasia of the overlying epithelium in a 48-year-old female patient, who presented to the emergency room with signs of intestinal obstruction...
October 18, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29061158/correction-to-influence-of-tumor-extent-on-central-lymph-node-metastasis-in-solitary-papillary-thyroid-microcarcinomas-a-retrospective-study-of-1092-patients
#17
Xingjie Yin, Chunping Liu, Yawen Guo, Xiaoyu Li, Na Shen, Xiangwang Zhao, Pan Yu, Shan Wang, Zeming Liu
No abstract text is available yet for this article.
October 17, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29041974/postoperative-functional-status-in-patients-with-supratentorial-superficial-low-grade-glioma
#18
Ji Zhang, Yin Sheng Chen, You-Ping Li, Zheng-Quan Zhu, Jian-Min Liu, Cheng-Cheng Guo, Qun-Ying Yang, Xiao-Li Wang, Ying-Hua Rao, Qing Mao, Wen-Yan Li, Lu Ma, Yun Qiang Yang, Shi-Yin Xiao
BACKGROUND: We investigated the functional status of adult supratentorial superficial low-grade glioma (ASS-LGG) after surgery and analyzed its relevant factors to guide the therapeutic strategy and improve the life quality of these patients. METHODS: Clinical materials from January 2008 to December 2010 in 104 adults with ASS-LGG were analyzed retrospectively. The follow-up period ranged from 6 months to 1.5 years. The logistic regression was used to evaluate the preoperative and postoperative variation of functional status in patients to disclose the relevant factors affecting postoperative functional status, such as age, gender, the duration of symptom, size and location of the tumor, hemisphere, resection degree, and tumor pathologic grade and preoperative Karnofsky performance status (Pre-KPS)...
October 17, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29037204/thoracodorsal-artery-perforator-flap-as-an-autologous-alternative-to-acellular-dermal-matrix
#19
Tarek Hashem, Ahmed Farahat
BACKGROUND: Thoracodorsal artery perforator (TDAP) flap is one of the relatively new techniques in breast reconstruction. This pedicled flap retains the benefits of perforator flaps as regards minimal donor site morbidity without the need for microvascular anastomosis. Its role in partial breast reconstruction has been well documented. However, there are few reports about the role of this flap in total breast reconstruction. METHODS: This study included 47 cases who presented to the breast unit of the National Cancer Institute of Cairo University from 2013 to 2015...
October 16, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29037198/prolonged-survival-of-patients-with-egfr-mutated-non-small-cell-lung-cancer-with-solitary-brain-metastases-treated-with-surgical-resection-of-brain-and-lung-lesions-followed-by-egfr-tkis
#20
Qi Gui, Jiangang Liu, Dapeng Li, Chengcheng Xu
BACKGROUND: The standard combination of initial and subsequent treatments of epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) patients with solitary brain metastases (BM) remain unclear. Thus, the management options and the progression-free survival (PFS) and the overall survival (OS) of EGFR-mutated NSCLC patients with solitary BM were investigated in the study. METHODS: We retrospectively reviewed the clinical data from NSCLC patients who harbored EGFR mutations and who presented solitary BM at diagnosis in our institute between 2012 and 2014...
October 16, 2017: World Journal of Surgical Oncology
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