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Lymphatic Research and Biology

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https://www.readbyqxmd.com/read/28135123/prefabricated-cervical-skin-flaps-for-hemi-facial-resurfacing-elucidating-the-natural-history-of-postoperative-edema-using-indocyanine-green
#1
Ke Li, Peiru Min, Parviz Sadigh, Luca Grassetti, Davide Lazzeri, Matteo Torresetti, Riccardo Marsili, Shaoqing Feng, Ningfei Liu, Yi Xin Zhang
BACKGROUND: The increases in capillary wall permeability and capillary hydrostatic pressure are considered to be the causes for the acute swelling seen in flaps; however, disruption of the circulating flap lymphatics could be another contributory factor. In this study we monitor the development of flap edema in a series of 18 prefabricated flaps and aim to delineate the natural history of this phenomenon by use of lymphography. METHODS: Postoperative swelling was monitored in a series of 18 pre-expanded prefabricated cervical skin flaps used for hemi-facial burns-scar resurfacing...
January 30, 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28323573/real-time-direct-evidence-of-the-superficial-lymphatic-drainage-effect-of-intermittent-pneumatic-compression-treatment-for-lower-limb-lymphedema
#2
Shinya Kitayama, Jiro Maegawa, Shinobu Matsubara, Shinji Kobayashi, Taro Mikami, Koichi Hirotomi, Shintaro Kagimoto
BACKGROUND: Intermittent pneumatic compression (IPC) is a widely used lymph drainage therapy that can be performed at home. However, the effectiveness of IPC for lymph drainage remains unclear. The aim of this study is to investigate the real-time change in the lymph flow velocity during IPC and consider which mode and pressure are best for treating lower limb lymphedema. METHODS AND RESULTS: Eight lower left limbs of 8 healthy volunteers and 17 lower limbs of 15 secondary lymphedema patients were investigated...
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28323572/bilateral-changes-in-deep-tissue-environment-after-manual-lymphatic-drainage-in-patients-with-breast-cancer-treatment-related-lymphedema
#3
Paula M C Donahue, Rachelle Crescenzi, Allison O Scott, Vaughn Braxton, Aditi Desai, Seth A Smith, John Jordi, Ingrid M Meszoely, Ana M Grau, Rondi M Kauffmann, Raeshell S Sweeting, Kandace Spotanski, Sheila H Ridner, Manus J Donahue
BACKGROUND: Breast cancer treatment-related lymphedema (BCRL) arises from a mechanical insufficiency following cancer therapies. Early BCRL detection and personalized intervention require an improved understanding of the physiological processes that initiate lymphatic impairment. Here, internal magnetic resonance imaging (MRI) measures of the tissue microenvironment were paired with clinical measures of tissue structure to test fundamental hypotheses regarding structural tissue and muscle changes after the commonly used therapeutic intervention of manual lymphatic drainage (MLD)...
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28323571/lymphatic-drainage-to-the-paravertebral-lymph-nodes-in-breast-cancer-patients
#4
Mirela Mariana Roman, Romain Barbieux, Olivier Leduc, Pierre Bourgeois
INTRODUCTION: Aberrant, altered, or blocked lymphatic drainage may contribute to the high recurrence rate of breast cancer. Thus, an efficient evaluation of lymphatic drainage from the breasts and/or upper limbs is essential in the management of lymphedema and in ipsilateral primary or contralateral recurrent breast cancer patients. There are very few reports of lymphatic drainage to the paravertebral lymph nodes in patients with a lymphedema after breast cancer surgery with or without reconstruction...
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28323570/-near-infrared-fluorescence-lymphatic-imaging-to-reconsider-occlusion-pressure-of-superficial-lymphatic-collectors-in-upper-extremities-of-healthy-volunteers-facts-and-or-artifact
#5
Pierre Bourgeois, Roman Barbieux
No abstract text is available yet for this article.
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28323569/isolated-human-lymphatic-vessels-and-lymphatic-endothelial-cells
#6
Stanley G Rockson
No abstract text is available yet for this article.
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28323568/update-march-2017
#7
Francine Blei
No abstract text is available yet for this article.
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28323567/reply-to-near-infrared-fluorescence-lymphatic-imaging-to-reconsider-occlusion-pressure-of-superficial-lymphatic-collectors-in-upper-extremities-of-health-volunteers-facts-and-or-artifacts-by-pierre-bourgeois-and-romain-barbieux
#8
https://www.readbyqxmd.com/read/28278070/blood-flow-velocity-in-brachial-and-subclavian-vessels-immediately-after-compressive-procedures-for-treatment-of-postcancer-therapy-lymphedema-in-breast-cancer-a-randomized-blind-clinical-trial
#9
Monique Silva Rezende, Ana Luiza Marsengo, Rinaldo Roberto de Jesus Guirro, Elaine Caldeira de Oliveira Guirro
OBJECTIVE: This study sought to evaluate the effect of elastic compression, functional compressive bandaging, and kinesiotherapy on blood flow of the upper limb with lymphedema secondary to the treatment of breast cancer. METHODS: This was a randomized blind crossover clinical trial with a washout period of 7 days between treatments. We evaluated 20 women with a mean age of 66.85 years (standard deviation = 11.76), undergoing three types of therapeutic procedures randomly applied by lot: kinesiotherapy, functional compressive bandaging + kinesiotherapy (FCB), and elastic compression + kinesiotherapy (EC)...
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28277926/the-value-of-using-a-skinfibrometer-for-diagnosis-and-assessment-of-secondary-lymphedema-and-associated-fibrosis-of-lower-limb-skin
#10
Di Sun, Ziyou Yu, Jiajia Chen, Li Wang, Linghua Han, Ningfei Liu
BACKGROUND: Skin fibrosis is a clinically serious pathological process of secondary lymphedema (SLE). The detection of latent or incipient skin fibrosis, including early tissue changes, using sensitive diagnostic equipment is essential. The SkinFibroMeter has been used in skin care; however, its ability to assess skin fibrosis in patients with SLE of the lower limb has not been explored. METHODS AND RESULTS: In this study, 45 female patients with secondary unilateral lower limb LE and 15 healthy female volunteers were enrolled...
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28277905/spontaneous-and-evoked-contractility-of-human-intestinal-lymphatic-vessels
#11
Niklas Telinius, Jens Majgaard, Sheyanth Mohanakumar, Einar Pahle, Jørn Nielsen, Vibeke Hjortdal, Christian Aalkjær, Donna Briggs Boedtkjer
BACKGROUND: Mesenteric lymphatic vessels (MLVs) from various animal species have been intensively studied. We aimed to establish the viability and basic contractile characteristics of human MLVs maintained in vitro and to determine the reactivity of MLVs with norepinephrine (NE) and substance P (SP) and to compare with the thoracic duct (TD). METHODS AND RESULTS: Isolated human lymphatic vessels were mounted on a wire myograph under isometric conditions and tension was recorded...
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28151088/lymph-drainage-during-wound-healing-in-a-hindlimb-lymphedema-mouse-model
#12
Emi Komatsu, Yukari Nakajima, Kanae Mukai, Tamae Urai, Kimi Asano, Mayumi Okuwa, Junko Sugama, Toshio Nakatani
BACKGROUND: Although lymphedematous skin exhibits delayed wound healing, little is known about lymph drainage during wound healing. We investigated the wound healing process in the presence of lymphatic dysfunction. METHODS AND RESULTS: The right inguinal lymph nodes (iLNs) and the surrounding tissue were excised in each mouse (the operation side), and a sham operation was performed in the left hindlimb (the control side). The next day, full-thickness wounds were made on both hindlimbs...
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28135127/elm-a-new-simple-and-economic-assay-to-measure-motility-of-lymphatic-endothelial-cells
#13
Fabio Torri, Patrizia Dell'Era, Emirena Garrafa
BACKGROUND: Relatively few attempts have been made to set up an assay that allows the measurement of lymphatic endothelial cells (LECs) motility. Nowadays, the most widely used methods involve adaptation of the Boyden chamber method or the wound scratch assay, both of them showing some limitations due to long and expensive setup and high variability. METHODS AND RESULTS: We propose a new, economic, and easy to setup LEC Motility (ELM) assay that will contribute to the study of lymphangiogenesis...
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28135124/comparisons-between-cancer-related-and-noncancer-related-lymphedema-an-overview-of-new-patients-referred-to-a-specialized-hospital-based-center-in-canada
#14
Shirin M Shallwani, Pamela Hodgson, Anna Towers
BACKGROUND: Lymphedema is an irreversible inflammatory condition caused by accumulated lymph fluid and is associated with chronic swelling and increased risk of cellulitis. Our objectives were to: (1) describe the patient population referred to a Canadian lymphedema center and (2) compare lymphedema characteristics between patients with cancer and patients with noncancer diagnoses. METHODS AND RESULTS: A retrospective cohort study was conducted of new patients referred for suspected lymphedema to a hospital-based center over a 2-year period...
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28135120/sf-36-shows-increased-quality-of-life-following-complete-reduction-of-postmastectomy-lymphedema-with-liposuction
#15
Mattias Hoffner, Shirin Bagheri, Emma Hansson, Jonas Manjer, Thomas Troëng, Håkan Brorson
Abstracts Background: Arm lymphedema after breast cancer surgery affects women both from physical and psychological points of view. Lymphedema leads to adipose tissue deposition. Liposuction and controlled compression therapy (CCT) reduces the lymphedema completely. METHODS AND RESULTS: Sixty female patients with arm lymphedema were followed for a 1-year period after surgery. The 36-item short-form health survey (SF-36) was used to assess health-related quality of life (HRQoL). Patients completed the SF-36 questionnaire before liposuction, and after 1, 3, 6, and 12 months...
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28128668/animal-models-of-secondary-lymphedema-new-approaches-in-the-search-for-therapeutic-options
#16
Rebecca Hadrian, Daniel Palmes
Secondary lymphedema is still a worldwide problem. Symptomatic approaches to lymphedema therapy have been mainly used, with complete decongestive therapy as the cornerstone. Due to a lack of regenerative therapy, researchers have established various animal models to obtain insights into pathomechanisms and to reveal the best therapeutic option. Since the first reproducible and reliable animal model of lymphedema was reported in dogs, the technique of circumferential excision of lymphatic tissue has been translated mainly to rodents to induce secondary lymphedema...
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/27673568/intrarater-reliability-of-tonometry-and-bioimpedance-spectroscopy-to-measure-tissue-compressibility-and-extracellular-fluid-in-the-legs-of-healthy-young-people-in-australia-and-myanmar
#17
Janet Douglass, Patricia Graves, Susan Gordon
BACKGROUND: Measurements of tissue compressibility and extracellular fluid (ECF) are used to monitor progression of lymphedema, a chronic swelling of the subcutaneous tissue. Later stages of lymphedema are characterized by fibrotic induration in the subcutis and hyperkeratosis of the skin. Several devices are available to measure these changes, but previous reliability and validity studies have been conducted primarily on adult women with unilateral arm lymphedema using contralateral limbs as controls...
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/27997312/lymphedema-in-head-and-neck-cancer
#18
Stanley G Rockson
No abstract text is available yet for this article.
December 2016: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/27997311/update-december-2016
#19
Francine Blei
No abstract text is available yet for this article.
December 2016: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/27997310/-unknown-title
#20
(no author information available yet)
No abstract text is available yet for this article.
December 2016: Lymphatic Research and Biology
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