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Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology

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https://www.readbyqxmd.com/read/28739084/the-repeatability-and-characteristics-of-right-ventricular-longitudinal-strain-imaging-by-speckle-tracking-echocardiography-in-healthy-dogs
#1
T Morita, K Nakamura, T Osuga, N Yokoyama, N Khoirun, K Morishita, N Sasaki, H Ohta, M Takiguchi
INTRODUCTION: To assess the repeatability and characteristics of echocardiographic indices of the right ventricular (RV) function derived from speckle-tracking echocardiography. ANIMALS: Fourteen laboratory Beagles and 103 privately owned dogs without cardiac disease were involved in this study. MATERIALS AND METHODS: Right ventricular longitudinal strain, strain rate, and a strain-related index for assessing RV dyssynchrony derived from speckle-tracking echocardiography were obtained by two different observers using five Beagles...
July 21, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28734621/use-of-n-butyl-cyanoacrylate-to-reduce-left-to-right-shunting-of-an-abdominal-arteriovenous-malformation-in-a-dog
#2
B D Eason, D F Hogan, C Lim, M J Hogan
A 9-month old castrated male Labradoodle presented to the cardiology service at Purdue University for evaluation of a low-grade murmur. Physical examination, thoracic radiography, and echocardiography were strongly supportive of an extracardiac left-to-right shunt. Subsequent evaluation with nuclear scintigraphy and computed tomography angiography revealed a large, complex arteriovenous malformation within the cranial abdomen. Staged interventional attenuation of the shunt was performed using n-butyl cyanoacrylate that resulted in a reduction in echocardiographic and nuclear scintigraphy derived shunt estimation...
July 19, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28734620/treatment-of-dogs-with-compensated-myxomatous-mitral-valve-disease-with-spironolactone-a-pilot-study
#3
M J Hezzell, A Boswood, J López-Alvarez, N Lötter, J Elliott
OBJECTIVES: Spironolactone improves outcome in dogs with advanced myxomatous mitral valve disease (MMVD). Its efficacy in preclinical MMVD is unknown. The hypothesis was the administration of spironolactone to dogs with compensated MMVD demonstrating risk factors for poorer prognosis will decrease the rate of disease progression. The aim was to provide pilot data to evaluate preliminary effects and sample size calculation for a definitive clinical trial. ANIMALS: Twenty-five client-owned dogs with MMVD with at least one of the following; left atrial to aortic ratio (LA:Ao) ≥ 1...
July 19, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28684243/plasma-l-citrulline-concentrations-in-l-arginine-supplemented-healthy-dogs
#4
K M Flynn, H B Kellihan, L A Trepanier
INTRODUCTION: To determine whether oral l-arginine increases plasma [l-citrulline] in dogs. ANIMALS: Eleven healthy staff-owned dogs were used in this study. MATERIALS AND METHODS: Dogs (n = 3) were given l-arginine (50mg/kg PO q8h) for 7 days, and plasma [l-arginine] and [l-citrulline] were analyzed by high performance liquid chromatography at baseline (BL), steady state trough, and 0.5, 1, 1.5, 2, 4, 6, and 8 h after final dosing on day 7...
July 3, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28666945/prevalence-and-diagnostic-characteristics-of-non-clinical-mitral-regurgitation-murmurs-in-north-american-whippets
#5
R L Stepien, H B Kellihan, V Luis Fuentes
OBJECTIVES: To assess the prevalence of functional ejection murmurs and murmurs of mitral regurgitation (MR) due to myxomatous mitral valve disease in healthy whippets; to assess the diagnostic value of auscultation to detect MR; and investigate the relationship between age and presence of echocardiographically documented MR (MRecho). ANIMALS: A total of 200 healthy client-owned Whippets, recruited at national shows between 2005 and 2009 were involved in this study...
June 27, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28615148/echocardiographic-assessments-of%C3%A2-longitudinal-left-ventricular-function-in%C3%A2-healthy-english-springer-spaniels
#6
D Dickson, R Shave, M Rishniw, M Patteson
OBJECTIVES: To establish reference intervals for echocardiographic measures of longitudinal left ventricular function in adult English Springer spaniel (ESS) dogs. ANIMALS: This study involved 42 healthy adult ESS. METHODS: Animals were prospectively recruited from a general practice population in the United Kingdom. Dogs were examined twice, at least 12 months apart, to exclude dogs with progressive cardiac disease. Mitral annular plane systolic excursion, tissue Doppler imaging mitral annular velocities and two-dimensional speckle-tracking echocardiographic left ventricular longitudinal strain and strain rate were measured...
June 11, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28602635/validation-of-a-method-for-quantitation-of-the-clopidogrel-active-metabolite-clopidogrel-clopidogrel-carboxylic-acid-and-2-oxo-clopidogrel-in-feline-plasma
#7
Janne G Lyngby, Michael H Court, Pamela M Lee
INTRODUCTION: The clopidogrel active metabolite (CAM) is unstable and challenging to quantitate. The objective was to validate a new method for stabilization and quantitation of CAM, clopidogrel, and the inactive metabolites clopidogrel carboxylic acid and 2-oxo-clopiodgrel in feline plasma. ANIMALS: Two healthy cats administered clopidogrel to demonstrate assay in vivo utility. MATERIALS AND METHODS: Stabilization of CAM was achieved by adding 2-bromo-3'methoxyacetophenone to blood tubes to form a derivatized CAM (CAM-D)...
June 8, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28576476/mitral-valve-repair-in-dogs-using-an-eptfe-chordal-implantation-device-a-pilot-study
#8
M Borgarelli, O Lanz, N Pavlisko, J A Abbott, G Menciotti, M Aherne, S M Lahmers, K K Lahmers, J S Gammie
OBJECTIVE: Mitral valve (MV) regurgitation due to degenerative MV disease is the leading cause of cardiac death in dogs. We carried out preliminary experiments to determine the feasibility and short-term effects of beating-heart MV repair using an expanded polytetrafluorethylene (ePTFE) chordal implantation device (Harpoon TSD-5) in dogs. ANIMALS: This study involved six healthy purpose-bred Beagles (weight range 8.9-11.4 kg). MATERIAL AND METHODS: Following a mini-thoracotomy performed under general anesthesia, the TSD-5 was used to place 1 or 2 artificial ePTFE cords on the anterior MV leaflet or the posterior MV leaflet via a left-ventricular transapical approach...
May 31, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28576478/intracardiac-echocardiography-use-during-transcatheter-device-closure-of-a-patent-ductus-arteriosus-in-a-dog
#9
V Chetboul, C Damoiseaux, L Behr, A Morlet, N S Moise, V Gouni, M Lavennes, J-L Pouchelon, F Laborde, N Borenstein
Intracardiac echocardiography (ICE) is used in humans for percutaneous interventional procedures, such as transcatheter device closures. Intracardiac echocardiography provides high-resolution imaging of cardiac structures with two-dimensional, M-mode, Doppler, and also three-dimensional modalities. The present report describes application of ICE during transcatheter occlusion of patent ductus arteriosus using a canine ductal occluder in a dog for which transesophageal echocardiography could not provide an optimal acoustic window...
May 30, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28576477/perceptions-of-transcatheter-device-closure-of-patent-ductus-arteriosus-in-veterinary-cardiology-and-evaluation-of-a-canine-model-to-simulate-device-placement-a-preliminary-study
#10
A B Saunders, L Keefe, S A Birch, M A Wierzbicki, D J Maitland
OBJECTIVES: The purpose of this study was to evaluate a canine patent ductus arteriosus (PDA) model developed for practicing device placement and to determine practices and perceptions regarding transcatheter closure of PDA from the veterinary cardiology community. METHOD: A silicone model was developed from images obtained from a dog with a PDA and device placement was performed with catheter equipment and a document camera to simulate fluoroscopy. A total of 36 individuals including 24 diplomates and 12 residents participated, and the feedback was obtained...
May 30, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28571753/real-time-3d-transesophageal-echocardiography-guided-closure-of-a-complicated-patent-ductus-arteriosus-in-a-dog
#11
K R Doocy, D A Nelson, A B Saunders
Advanced imaging modalities are becoming more widely available in veterinary cardiology, including the use of transesophageal echocardiography (TEE) during occlusion of patent ductus arteriosus (PDA) in dogs. The dog in this report had a complex history of attempted ligation and a large PDA that initially precluded device placement thereby limiting the options for PDA closure. Following a second thoracotomy and partial ligation, the morphology of the PDA was altered and device occlusion was an option. Angiographic assessment of the PDA was limited by the presence of hemoclips, and the direction of ductal flow related to the change in anatomy following ligature placement...
May 29, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28566246/conversion-of-atrial-dissociation-with-lidocaine-in-a-dog
#12
C L Thorn, R Vezina-Audette, A R Gelzer
A 3-year-old healthy dog was presented for abdominal surgery following ingestion of razor blades. An electrocardiogram revealed a regular sinus bradycardia with normal P waves at a heart rate of 45 bpm. In addition, low-amplitude positive deflections (p' waves) were visualized at a regular interval and rapid rate of 250 bpm, dissociated from the normal sinus P waves. A tentative diagnosis of atrial dissociation was proposed. Administration of lidocaine abolished the p' waves. This case describes atrial dissociation observed following premedication that was successfully terminated using lidocaine in a healthy dog...
May 26, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28478943/feasibility-safety-and-tolerance-of-subcutaneous-synthetic-canine-b-type-natriuretic-peptide-syncbnp-in-healthy-dogs-and-dogs-with-stage-b1-mitral-valve-disease
#13
M A Oyama, P F Solter, C L Thorn, J A Stern
INTRODUCTION: An important aspect of heart failure is the progressive ineffectiveness of the salutary natriuretic peptide system and its secondary messenger, 3',5'-cyclic guanosine monophosphate (cGMP). In humans with acute heart failure, administration of exogenous natriuretic peptide is associated with improvement in clinical signs and reduction of cardiac filling pressures. This study aimed to determine the feasibility, tolerance, and safety of subcutaneous (SC) synthetic canine B-type natriuretic peptide (syncBNP) administration in dogs...
May 3, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28478942/follow-up-of-troponin-i-concentration-in-dogs-with-atrioventricular-block-and-dual-chamber-pacing-in-a-case-matched-study
#14
Nicola Wiedemann, Nicolai Hildebrandt, Gabriel Wurtinger, Estelle Henrich, Esther Hassdenteufel, Matthias Schneider
BACKGROUND: Increased cardiac troponin I (cTnI) concentration has been reported in dogs with atrioventricular (AV) block before and shortly following pacemaker implantation. The role of AV dyssynchrony, age, or concurrent cardiac disease on cTnI concentration remains unknown. OBJECTIVES: To investigate change in cTnI concentration following dual-chamber pacemaker implantation on short- and long-term follow-up and to compare cTnI values to a case-matched control group...
May 3, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28579307/tricuspid-annular-plane-systolic-excursion-in-dogs-with-myxomatous-mitral-valve-disease-with-and-without-pulmonary-hypertension
#15
H Poser, M Berlanda, M Monacolli, B Contiero, A Coltro, C Guglielmini
OBJECTIVES: To evaluate tricuspid annular plane systolic excursion (TAPSE) in dogs with myxomatous mitral valve disease (MMVD) with or without pulmonary hypertension (PH) and to study the correlations with clinical and echocardiographic parameters. ANIMALS: The study population included 99 dogs with MMVD and tricuspid regurgitation. METHODS: This is a prospective clinical study. All dogs received a transthoracic echocardiographic evaluation, including 2D, M-mode, echo-Doppler, and tissue Doppler measurements...
June 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28578822/survival-time-with-pacemaker-implantation-for-dogs-diagnosed-with-persistent-atrial-standstill
#16
R M Cervenec, C D Stauthammer, D M Fine, H B Kellihan, B A Scansen
OBJECTIVES: To evaluate survival time in dogs with persistent atrial standstill after pacemaker implantation and to compare the survival times for cardiac-related vs. non-cardiac deaths. Secondary objectives were to evaluate the effects of breed and the presence of congestive heart failure (CHF) at the time of diagnosis on survival time. ANIMALS: Twenty dogs with persistent atrial standstill and pacemaker implantation. METHODS: Medical records were searched to identify dogs diagnosed with persistent atrial standstill based on electrocardiogram that underwent pacemaker implantation...
June 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28576479/aldosterone-breakthrough-in-dogs-with-naturally-occurring-myxomatous-mitral-valve-disease
#17
M K Ames, C E Atkins, A Eriksson, A M Hess
INTRODUCTION: Aldosterone breakthrough (ABT) is the condition in which angiotensin converting enzyme inhibitors (ACEIs) and/or angiotensin receptor blockers fail to effectively suppress the activity of the renin angiotensin aldosterone system. The objective of this study was to determine if ABT occurs in dogs with naturally occurring myxomatous mitral valve disease receiving an ACEI, using the urine aldosterone to creatinine ratio (UAldo:C) as a measure of renin angiotensin aldosterone system activation...
June 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28435002/systemic-arterial-hypertension-secondary-to-chronic-kidney-disease-in-two-captive-born-large-felids
#18
A Leclerc, E Trehiou-Sechi, E M Greunz, C Damoiseaux, J Bouvard, V Chetboul
Systemic arterial hypertension (SHT) has been widely described in the domestic cat (Felis catus). In these feline patients, SHT is considered as the most common vascular disorder of middle-aged to older animals, and secondary SHT related to chronic kidney disease (CKD) represents the most common form of the disease. We describe here the first two cases of spontaneous SHT in large felids, i.e. one 18-year old, 34.4 kg, male North-Chinese leopard (Panthera pardus japonensis, case #1) and one 20-year old, 28...
April 20, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28291708/transvenous-electrical-cardioversion-of-atrial-fibrillation-in-two-dogs
#19
S W Jung, D K Newhard, K Harrelson
Atrial fibrillation is characterized by uncoordinated electrical activation of the atria that leads to the loss of atrial mechanical function and atrial fibrosis as a substrate promoting maintenance of rhythm abnormality. Transvenous electrical cardioversion has not been previously reported in the dog. The authors demonstrate the use of this technique for successful cardioversion of atrial fibrillation in two dogs with dilated cardiomyopathy.
April 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28279678/mitral-valve-morphology-assessed-by-three-dimensional-transthoracic-echocardiography-in-healthy-dogs-and-dogs-with-myxomatous-mitral-valve-disease
#20
G Menciotti, M Borgarelli, M Aherne, S Wesselowski, J Häggström, I Ljungvall, S M Lahmers, J A Abbott
OBJECTIVE: To assess differences in morphology of the mitral valve (MV) between healthy dogs and dogs affected by myxomatous mitral valve disease (MMVD) using real-time transthoracic three-dimensional echocardiography (RT3DE). ANIMALS: Thirty-four were normal dogs and 79 dogs were affected by MMVD. METHODS: Real-time transthoracic three-dimensional echocardiography mitral datasets were digitally recorded and analyzed using dedicated software...
April 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
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