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Eye & Contact Lens

Xuemin Zhang, Saujanya Vadoothker, Wuqaas M Munir, Osamah Saeedi
OBJECTIVES: Ocular surface disease frequently coexists with glaucoma and may be initiated or exacerbated by topical glaucoma medications. We performed a review of current literature to assess the prevalence, causes, and treatment of ocular surface disease in glaucoma patients, specifically those on topical therapy. METHODS: A Pubmed database search was conducted. A total of 720 articles published from 1972 to 2018 were found in relation with ocular surface disease, glaucoma, and glaucoma medications...
August 30, 2018: Eye & Contact Lens
Hendrik Walther, Lakshman N Subbaraman, Lyndon Jones
PURPOSE: To determine the efficacy of multipurpose solutions (MPSs) on the removal of cholesterol deposits from silicone hydrogel (SH) contact lens materials using an in vitro model. MATERIALS AND METHODS: Five SH lens materials: senofilcon A, comfilcon A, balafilcon A, lotrafilcon A, and lotrafilcon B were removed from the blister pack (n=4 for each lens type), incubated for 7 days at 37°C in an artificial tear solution containing C radiolabeled cholesterol. Thereafter, lenses were stored in a preserved saline solution control (Sensitive Eyes Saline Plus) or cleaned with 1 of the 5 MPSs incorporating different preservatives (POLYQUAD/ALDOX, polyquaternium-1/alexidine, polyquaternium-1/PHMB, and 2 based on PHMB alone) using a rub and rinse technique, according to the manufacturer's recommendations, and stored in the MPS for a minimum of 6 hr...
August 30, 2018: Eye & Contact Lens
Manal M Gabriel, Cindy McAnally, John Bartell, Rhonda Walters, Linda Clark, Monica Crary, Stephen Shannon
PURPOSE: To compare the antimicrobial effects of CLEAR CARE, a 3% hydrogen peroxide (H2O2) solution formulated for simultaneous cleaning, daily protein removal, disinfection, and storage of soft (hydrophilic) hydrogel, silicone hydrogel, and gas-permeable contact lenses, and CLEAR CARE PLUS, consisting of the 3% H2O2 solution plus a novel wetting agent, polyoxyethylene-polyoxybutylene (EOBO-21). METHODS: Three lots each of the 2 solutions were incubated with 5 compendial microorganisms required by the Food and Drug Administration (FDA) 510(k) and International Organization for Standardization (ISO) 14729 stand-alone procedures, 4 clinical isolates of Gram-positive and Gram-negative bacteria, and trophozoites and cysts of 2 Acanthamoeba strains that are associated with microbial keratitis...
August 21, 2018: Eye & Contact Lens
Kofi Asiedu, Selassie K Dzasimatu, Samuel Kyei
OBJECTIVE: To determine the impact of dry eye on quality of life, depression, anxiety, and stress in a healthy youthful clinical sample. METHODS: This was a clinic-based cross-sectional study. Subjects were patients visiting the University of Cape Coast Eye Clinic for comprehensive eye examination. The age range for recruitment into the study was 16 to 35 years. Eligible participants completed three questionnaires namely the Ocular Surface Disease Index (OSDI), short version of the depression, anxiety, and stress scale (DASS-21), dry eye quality of life score (DEQS) questionnaire...
August 20, 2018: Eye & Contact Lens
Edward Lum, Melanie C Corbett, Paul J Murphy
The cornea is densely innervated with free nerve endings to provide a high level of sensitivity to foreign bodies or noxious substances. They also provide trophic support to the tissues of the cornea and facilitate their repair and replacement. Any reduction in the function of the nerve endings through disease, contact lens wear, or surgery may lead to corneal disease, damage, or reduced healing. Assessment of the corneal nerve function can be made by the use of specialized instruments (aesthesiometers) that stimulate the corneal nerves using different modalities-mechanical, chemical, and thermal...
August 7, 2018: Eye & Contact Lens
Ana Amorim-de-Sousa, Ana Cláudia Vieira, José Manuel González-Méijome, António Queirós
PURPOSE: Corneal front-surface asphericity is directly related with the optical quality of the eye and with contact lenses fitting. The purpose of this study was to evaluate the corneal asphericity as a function of age, sex, and refractive error measured with autokeratometry and corneal topography and its long-term changes (5- to 10-year period). METHODS: The asphericity and corneal curvature were obtained with the autorefractometer/autokeratometer NIDEK ARK-700A and with the videokeratoscope MODI 2...
August 7, 2018: Eye & Contact Lens
Jerome Ozkan, Percy Lazon de la Jara, Mark Willcox
AIM: A series of proof-of-principle extended wear (EW) contact lens studies were conducted to assess what effect different interventions had on adverse events (AEs). Comparative analysis of AEs across studies was conducted to determine whether some interventions were more effective at reducing inflammatory AEs. METHOD: Multiple logistic regression analysis of AEs from 30-day EW studies each with a different intervention including (1) nightly replacement (NR) of lenses, (2) morning replacement (MR) of lenses, (3) instillation of prophylactic antibiotic drops (AB) each morning/evening, (4) daily lens cleaning (LC) each morning...
August 3, 2018: Eye & Contact Lens
Riping Zhang, Lixia Sun, Jinyu Li, Antony Law, Vishal Jhanji, Mingzhi Zhang
PURPOSE: To compare the visual and refractive outcomes of transepithelial photorefractive keratectomy (Trans-PRK) and sub-Bowman femtosecond-assisted laser in situ keratomileusis (SBK). SETTING: University hospital. DESIGN: Retrospective, comparative study. METHODS: Two hundred forty patients with myopia and myopic astigmatism underwent SBK (n=157) or Trans-PRK (n=83). The main outcome measures included manifest spherical equivalent refraction (MRSE), logarithm of the minimum angle of resolution uncorrected visual acuity (UCVA), and best-corrected visual acuity (BCVA), which were evaluated at 1 and 3 months postoperatively...
July 30, 2018: Eye & Contact Lens
Javier González-Pérez, Ángel Sánchez García, César Villa-Collar
OBJECTIVES: To compare the visual-related quality of life in myopic subjects with different refractive treatments such as continuous wear of silicone-hydrogel contact lenses (CL), corneal refractive therapy (CRT), and laser-assisted in situ keratomileusis (LASIK). METHODS: The National Eye Institute Refractive Error Quality of Life Instrument (NEI RQL-42) questionnaire was administered to 96 subjects with a mean age of 30.0±7.9 years. There were 72 myopic subjects with a mean spherical equivalent of -2...
July 25, 2018: Eye & Contact Lens
Daddi Fadel
INTRODUCTION: The advent of high oxygen permeability (Dk) of rigid contact lens materials has reduced complications related to hypoxia when using scleral contact lenses (ScCLs). However, new issues and complications have emerged. Some of these issues and complications are caused by the nonoptimal fitting relationship with the underlying ocular surface, which may pose a challenge in their management. METHOD: PubMed searches using different keywords and an investigation into the issues and complications etiology were conducted...
July 20, 2018: Eye & Contact Lens
Esraa El-Mayah, Mohamed Anis, Mohsen Salem, David Pinero, Mohamed Hosny
PURPOSE: To compare Q-adjusted femtosecond-assisted laser in situ keratomileusis (FS-LASIK) and small-incision lenticule extraction (SMILE) in terms of safety, efficacy, and predictability, as well as in terms of changes in dry eye parameters, corneal biomechanics, higher-order aberrations (HOAs), and corneal asphericity. METHODS: A total of 60 eyes were enrolled in this prospective comparative study: 30 underwent SMILE and 30 underwent FS-LASIK. Changes in manifest refraction, uncorrected distance visual acuity and corrected distance visual acuity, corneal topography, corneal hysteresis (CH), and corneal resistance factor (CRF) (Ocular Response Analyzer, ORA), and dry eye parameters were evaluated during a 3-month follow-up...
July 17, 2018: Eye & Contact Lens
Mustafa Doğan, Serkan Özcan, Gürsel Acartürk, Çiğdem Özdemir
PURPOSE: To evaluate the ocular surface changes and tear-film functions in patients with inflammatory bowel disease (IBD). METHODS: The IBD group included 57 patients, and the control group included 29 healthy individuals. The Schirmer I test, tear breakup time (TBUT), corneal and conjunctiva fluorescent staining, and conjunctival impression cytology tests were performed to both groups. RESULTS: The rate of dry eye was 56.1% and 10.3% in the IBD and control groups, respectively, as assessed by the Schirmer I test (P<0...
July 12, 2018: Eye & Contact Lens
Maria Serramito-Blanco, Carlos Carpena-Torres, Jesús Carballo, David Piñero, Michael Lipson, Gonzalo Carracedo
OBJECTIVE: To evaluate changes in the anterior corneal curvature and aberrometry after scleral contact lens wear in keratoconus (KC) subjects with and without intracorneal ring segments (ICRS). METHODS: Twenty-six subjects diagnosed with keratoconus were selected to participate in the study. Subjects were divided into 2 groups, those with ICRS (KC-ICRS group) and those without ICRS (KC group). Subjects were instructed to wear 16.5-mm scleral lenses for 8 hours. Topographic and aberrometric parameters were evaluated before lens wear and immediately after lens removal...
July 12, 2018: Eye & Contact Lens
Eisuke Shimizu, Takefumi Yamaguchi, Kazuo Tsubota, Jun Shimazaki
OBJECTIVES: To evaluate corneal higher-order aberrations (HOAs) in eyes with corneal scar after traumatic perforation and their correlation with visual acuity. METHODS: This retrospective consecutive case study included 40 eyes of 40 consecutive patients (mean age, 39.2±21.6 years), treated for traumatic corneal perforation at Tokyo Dental College, and 18 normal control eyes. Higher-order aberrations of anterior and posterior corneal surfaces and total cornea were analyzed by swept-source optical coherence tomography...
July 12, 2018: Eye & Contact Lens
Hassan Hashemi, Mehdi Khabazkhoob, Reza Pakzad, Salomeh Bakhshi, Hadi Ostadimoghaddam, Amir Asaharlous, Reihaneh Yekta, Mohamadreza Aghamirsalim, Abbasali Yekta
OBJECTIVES: This study aims to determine the diagnostic ability of Pentacam indices for keratoconus and identifying the best index for differentiating diseased from normal cases. METHOD: In this study, 150 keratoconus patients and 150 refractive surgery candidates with a definitive diagnosis of normal healthy corneas were enrolled. Initially, the placido disk topography imaging was performed. The keratoconus and normal corneas were defined based on placido disk topographic data from Rabinowitz-McDonnell...
July 12, 2018: Eye & Contact Lens
Khosrow Jadidi, Saman Mohazzab-Torabi, Shiva Pirhadi, Mostafa Naderi, Abbasali Yekta, Sara Sardari, Mehdi Khabazkhoob
PURPOSE: This study compares the corneal biomechanical properties, as measured with Corvis ST, in three groups of cases with delayed-onset mustard gas keratopathy (DMGK), chronic corneal scarring (CCS), and those with normal corneas. METHODS: Forty-five eyes were enrolled in the DMGK, CCS, and normal groups (15 eyes each). All patients were examined with the slitlamp and Corvis ST. Extracted corneal biomechanical parameters included first and second applanation time (AT1, AT2), first and second applanation length (AL1, AL2), first and second applanation velocity (AV1, AV2), deformation amplitude (DA), highest concavity time, peak distance, highest concavity radius (HCR), central corneal thickness, corrected intraocular pressure (IOP), and noncorrected IOP...
July 12, 2018: Eye & Contact Lens
Caterina Sarnicola, Asim V Farooq, Kathryn Colby
Fuchs endothelial corneal dystrophy (FECD) is the most common indication for corneal transplantation in the United States, accounting 36% of the almost 47,000 transplants performed in 2016. Although the surgical management of FECD has undergone a revolution over the past 20 years, its pathogenesis remains elusive, with multiple putative disease pathways and an ever increasing number of candidate genes thought to play a role. This review will summarize the recent advancements in our understanding of the biology of FECD, including potential parallels with neurodegenerative disease like amyotrophic lateral sclerosis and will highlight prospects for future treatment advances...
July 12, 2018: Eye & Contact Lens
Ritu Arora, Aditi Manudhane, Parul Jain, Jawahar Lal Goyal
PURPOSE: To describe a new surgical technique "crescentic tuck in lamellar keratoplasty" for the management of advanced pellucid marginal corneal degeneration (PMCD). METHODS: A 45-year-old man with advanced PMCD and maximal thinning in the inferior juxtalimbal periphery underwent a crescentic lamellar keratoplasty in the right eye. Best-corrected visual acuity was 6/60 with no further improvement because of severe irregular astigmatism. Thinnest pachymetry in the peripheral cornea was 280 μm...
September 2018: Eye & Contact Lens
William Ngo, Sruthi Srinivasan, Lyndon Jones
PURPOSE: To quantify the strength of association of dry eye (DE) symptoms to DE diagnostic tests in age-matched females. METHODS: Twenty females with DE symptoms (Ocular Surface Disease Index, OSDI, ≥13) were age-matched with 20 females without DE symptoms (OSDI<13) in this cross-sectional study. Noninvasive tear breakup time (NIBUT), ocular staining, meibum quality, number of obstructed meibomian glands (MGs), lid wiper epitheliopathy, Marx line placement, eyelid margin score, Schirmer test, meibography, and visual acuity were assessed in both groups...
September 2018: Eye & Contact Lens
Andrzej Grzybowski, Piotr Kanclerz
No abstract text is available yet for this article.
September 2018: Eye & Contact Lens
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