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Eye & Contact Lens

Tatsuhiko Sato, Shizuka Koh, Yu-Ichi Yasukura, Masanori Kanai, Yumi Noguchi, Vishal Jhanji, Kohji Nishida
OBJECTIVES: Because vitrectomy-associated postoperative ocular surface changes are not well known, we evaluated such changes before and after vitrectomy in eyes with posterior segment diseases and investigated their associations with patients' characteristics and surgical procedures. METHODS: Thirty-five eyes of 32 consecutive patients (16 women; average age 66.6±11.1 years) were included in this prospective, noncomparative case series from tertiary care university hospital...
November 7, 2018: Eye & Contact Lens
Noel A Brennan, Xu Cheng
PURPOSE: To subject a number of commonly held beliefs or areas of confusion in the myopia field to scientific scrutiny. METHOD: A collection of statements about myopia are provided with references to demonstrate that a section of the research or clinical community supports the statement. The topics under discussion are reviewed critically with reference to the literature. RESULTS: The following statements are considered to lack sufficient supporting data to be considered as evidence-based: low-dose (0...
November 7, 2018: Eye & Contact Lens
Chang Li, Xiaofeng Zhang, Yun Wang, Mengmeng Li
OBJECTIVES: We aim to use the ovariectomized cynomolgus monkey to observe the effect of long-term changes of sex hormone levels on ocular surface. METHODS: Six healthy adolescent cynomolgus monkeys were randomly assigned to control and experimental groups (n=3/group). Bilateral ovariectomy was performed in experimental group, and sham operation was performed on control animals with their ovaries reserved. The concentrations of serum estradiol and testosterone in cynomolgus monkeys' lower-limb venous were detected by radioimmunoassay before surgery, and at 6, 12, 18, and 24 months after the surgery...
October 31, 2018: Eye & Contact Lens
Mamoru Ogawa, Cem Simsek, Takashi Kojima, Taeko Nagata, Ayako Igarashi, Tetsuya Kawakita, Murat Dogru, Jun Shimazaki, Kazuo Tsubota
OBJECTIVES: To evaluate the in vitro effects of 1-mM rebamipide ophthalmic solution on the expression of inflammatory cytokines and MUC5AC in Cu, Zn-superoxide dismutase-1 (SOD-1) knock-down conjunctival epithelium. METHODS: Conjunctival epithelium from C57BL/6 wild-type mice was cultured and treated with rebamipide ophthalmic solution. Using cytometric bead array, we examined the levels of interleukin-(IL)-6, IL-10, IL-17, monocyte chemoattractant protein-1, interferon-γ (INF-γ), tumor necrosis factor, and IL-12p70 in the culture supernatants...
October 25, 2018: Eye & Contact Lens
Natsume Suzuki, Takefumi Yamaguchi, Daisuke Tomida, Kazuo Tsubota, Jun Shimazaki
PURPOSE: To evaluate the incidence of the Descemet membrane (DM) folds after deep anterior lamellar keratoplasty (DALK) in treating keratoconus. We also evaluated the influence of DM folds and corneal higher-order aberrations (HOAs) on visual acuity after DALK. METHODS: This retrospective study included 89 consecutive eyes of 87 patients who underwent DALK for the treatment of keratoconus at Tokyo Dental College Ichikawa General Hospital from April 2002 to June 2017...
October 22, 2018: Eye & Contact Lens
David P Piñero, Antonio Martínez-Abad, Roberto Soto-Negro, Miguel Angel Ariza-Gracia, Gonzalo Carracedo
OBJECTIVE: To characterize peculiarities of the corneoscleral geometry in healthy eyes. METHODS: This is a prospective case series including 88 healthy eyes of 88 patients with an age ranging from 21 to 73 years. A complete ocular examination was performed with emphasis on the analysis of the corneoscleral topographic profile with the Fourier transform profilometer Eye Surface Profiler (Eaglet-Eye BV, Houten, the Netherlands). The distribution of different topographic parameters was evaluated, as well as the correlations between corneal and scleroconjunctival parameters...
October 15, 2018: Eye & Contact Lens
Mark A Bullimore, Stephen Slade, Paul Yoo, Todd Otani
OBJECTIVES: To evaluate the repeatability and reproducibility of the Carl Zeiss Meditec IOLMaster 700, which uses swept-source optical coherence tomography technology, along with its agreement with the IOLMaster 500 and Lenstar LS 900. METHODS: In a clinical practice, complete measurements were taken on one eye of 100 subjects: 51 with cataracts and 49 with clear lenses. Three sets of measurements were taken by 3 operators with three different IOLMaster 700 units, and one operator took 3 measurements with the IOLMaster 500 and the Lenstar...
October 15, 2018: Eye & Contact Lens
Shyam Panthi, Jianzhong Chen, Landon Wilson, Jason J Nichols
PURPOSE: Lipid mediators of inflammation are a group of signaling molecules produced by various cells under physiological conditions and modulate the inflammatory process during various pathologic conditions. Although eicosanoids and F2-isoprostanes are recognized lipid mediators of inflammation, there is no consensus yet on the extraction and mass spectrometry (MS) method for their analysis in individual human tear samples. Thus, the aim of this study was to develop an optimal method for extraction of lipid mediators of inflammation in the tear film and evaluate MS techniques for their analysis...
October 5, 2018: Eye & Contact Lens
Tao Li, Xiaodong Zhou, Xuefeng Chen, Huihong Qi, Qile Gao
PURPOSE: To examine the prevalence of refractive error and some associated factors in Chinese preschool children. METHODS: The Jinshan District Eye Study was a school-based survey of eye health in a large sample of 4- to 6-year-olds attending kindergartens from May 2013 to December 2013 in Shanghai. Refractive error was measured using an autorefractor under noncycloplegic conditions. Axial length (AL) was measured with an ocular biometry system. In addition, body height and weight were also recorded...
October 4, 2018: Eye & Contact Lens
Naohiko Aketa, Megumi Shinzawa, Motoko Kawashima, Murat Dogru, Shosei Okamoto, Kazuo Tsubota, Jun Shimazaki
PURPOSE: To evaluate the clinical effectiveness of expression treatment on meibomian gland disease (MGD). METHODS: Seventeen right eyes of 17 patients with MGD were divided into 3 groups in this randomized prospective clinical study: no expression group: routine treatment with no expression (five patients, five eyes); digital expression group: routine treatment with digital expression (five patients, five eyes); and plate expression group: routine treatment with plate expression (seven patients, seven eyes)...
September 21, 2018: Eye & Contact Lens
Xuemin Zhang, Saujanya Vadoothker, Wuqaas M Munir, Osamah Saeedi
OBJECTIVES: Ocular surface disease frequently coexists with glaucoma and may be initiated or exacerbated by topical glaucoma medications. We performed a review of current literature to assess the prevalence, causes, and treatment of ocular surface disease in glaucoma patients, specifically those on topical therapy. METHODS: A Pubmed database search was conducted. A total of 720 articles published from 1972 to 2018 were found in relation with ocular surface disease, glaucoma, and glaucoma medications...
August 30, 2018: Eye & Contact Lens
Hendrik Walther, Lakshman N Subbaraman, Lyndon Jones
PURPOSE: To determine the efficacy of multipurpose solutions (MPSs) on the removal of cholesterol deposits from silicone hydrogel (SH) contact lens materials using an in vitro model. MATERIALS AND METHODS: Five SH lens materials: senofilcon A, comfilcon A, balafilcon A, lotrafilcon A, and lotrafilcon B were removed from the blister pack (n=4 for each lens type), incubated for 7 days at 37°C in an artificial tear solution containing C radiolabeled cholesterol. Thereafter, lenses were stored in a preserved saline solution control (Sensitive Eyes Saline Plus) or cleaned with 1 of the 5 MPSs incorporating different preservatives (POLYQUAD/ALDOX, polyquaternium-1/alexidine, polyquaternium-1/PHMB, and 2 based on PHMB alone) using a rub and rinse technique, according to the manufacturer's recommendations, and stored in the MPS for a minimum of 6 hr...
August 30, 2018: Eye & Contact Lens
Mohaddeseh Alamdar, Ebrahim Jafarzadehpur, Ali Mirzajani, Abbas Ali Yekta, Mehdi Khabazkhoob
PURPOSE: To compare the visual acuity and refractive error using OPDIII and subjective findings in visually normal subjects. METHOD: This study was performed on 75 participants (134 eyes) with an age range of 18 to 35 years. Visual acuity was evaluated using both subjective Snellen chart and OPDIII devices. Also, OPDIII objective refraction was compared with subjective refraction. Paired t test was used to compare mean visual acuity and refractive error. The 95% limits of agreement (LOAs) were reported to evaluate the agreement between subjective and objective methods...
November 2018: Eye & Contact Lens
Katherine Duncan, Jeff Parker, Caroline Hoover, Thomas D Lindquist, Bennie H Jeng
PURPOSE: The incidence of postkeratoplasty fungal infection is increasing in the United States, and our most commonly used corneal storage medium, Optisol-GS, contains antibiotics but no antifungal agents. We previously demonstrated the efficacy of amphotericin B additives in eliminating Candida albicans contaminants in Optisol-GS. The purpose of this study was to determine whether amphotericin B would also be efficacious against Fusarium solani and Aspergillus fumigatus. METHODS: Vials of Optisol-GS were supplemented with 0...
November 2018: Eye & Contact Lens
Veysel Aykut, Ahmet Elbay, Fehim Esen, Gulsen Kocaman, Emine Savran Elibol, Halit Oguz
OBJECTIVE: Migraine is a central sensitization disease characterized by recurrent unilateral headache. The aim of this study was to evaluate corneal sensitivity and associated findings in patients with migraine. METHODS: In this study, we included 58 patients with migraine (52 female and 6 male, mean age: 32.98±8.51 years) and 30 healthy control subjects (27 females and 3 males, mean age: 35.29±8.00 years). Only patients who did not have any eye disease were included in this study...
November 2018: Eye & Contact Lens
Hirlana Gomes Almeida, Newton Kara-José, Richard Yudi Hida, Newton Kara-Junior
PURPOSE: To analyze 15-year of corneal transplant in Brazil. METHODS: Cross-sectional, retrospective, observational, and analytical study, between available data from the Brazilian Transplant Registry (January 2002-December 2016), collected by the Brazilian Association of Organ Transplantation was performed. The variables analyzed per year were number of corneal transplants, corneal transplants per million people (pmp), corneal transplant teams, and individuals on the waiting list for corneal transplants...
November 2018: Eye & Contact Lens
Kofi Asiedu, Selassie K Dzasimatu, Samuel Kyei
OBJECTIVE: To determine the impact of dry eye on quality of life, depression, anxiety, and stress in a healthy youthful clinical sample. METHODS: This was a clinic-based cross-sectional study. Subjects were patients visiting the University of Cape Coast Eye Clinic for comprehensive eye examination. The age range for recruitment into the study was 16 to 35 years. Eligible participants completed three questionnaires namely the Ocular Surface Disease Index (OSDI), short version of the depression, anxiety, and stress scale (DASS-21), dry eye quality of life score (DEQS) questionnaire...
November 2018: Eye & Contact Lens
Esraa El-Mayah, Mohamed Anis, Mohsen Salem, David Pinero, Mohamed Hosny
PURPOSE: To compare Q-adjusted femtosecond-assisted laser in situ keratomileusis (FS-LASIK) and small-incision lenticule extraction (SMILE) in terms of safety, efficacy, and predictability, as well as in terms of changes in dry eye parameters, corneal biomechanics, higher-order aberrations (HOAs), and corneal asphericity. METHODS: A total of 60 eyes were enrolled in this prospective comparative study: 30 underwent SMILE and 30 underwent FS-LASIK. Changes in manifest refraction, uncorrected distance visual acuity and corrected distance visual acuity, corneal topography, corneal hysteresis (CH), and corneal resistance factor (CRF) (Ocular Response Analyzer, ORA), and dry eye parameters were evaluated during a 3-month follow-up...
November 2018: Eye & Contact Lens
Mustafa Doğan, Serkan Özcan, Gürsel Acartürk, Çiğdem Özdemir
PURPOSE: To evaluate the ocular surface changes and tear-film functions in patients with inflammatory bowel disease (IBD). METHODS: The IBD group included 57 patients, and the control group included 29 healthy individuals. The Schirmer I test, tear breakup time (TBUT), corneal and conjunctiva fluorescent staining, and conjunctival impression cytology tests were performed to both groups. RESULTS: The rate of dry eye was 56.1% and 10.3% in the IBD and control groups, respectively, as assessed by the Schirmer I test (P<0...
November 2018: Eye & Contact Lens
Abdullah Kaya, Canan Gürdal
Demodex is an important pathogen in ophthalmology. It is believed to cause a variety of eyelid and eyelash diseases. Currently, light microscopes are being used for imaging demodex. However, microscopes are not available everywhere. Also, it is not cost-effective to perform light microscopy in every case. In this case, we demonstrate a new method: imaging demodex using cell phone. A 90-diopter noncontact double aspheric lens was attached to the posterior camera of the smartphone with clear tape. An eyelash of a patient with blepharitis was removed...
November 2018: Eye & Contact Lens
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