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Annals of Hepatology

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https://www.readbyqxmd.com/read/27740535/an-acknowledgement
#1
(no author information available yet)
No abstract text is available yet for this article.
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740534/%C3%A2-the-effect-of-ursodeoxycholic-acid-in-cystic-cholangiopathies
#2
Frank Lammert, Nahum Méndez-Sánchez
No abstract text is available yet for this article.
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740533/%C3%A2-reply-to-the-letter-to-the-editor
#3
Sara Bignulin, Edmondo Falleti, Sara Cmet, Dario Cappello, Annarosa Cussigh, Ilaria Lenisa, Denis Dissegna, Fabio Pugliese, Cinzia Vivarelli, Carlo Fabris, Pierluigi Toniutto
No abstract text is available yet for this article.
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740532/%C3%A2-usefulness-of-acoustic-radiation-force-impulse-in-liver-fibrosis-assessment-after-liver-transplant
#4
Veysel Özalper, Coskun Ozturker, Guner X Guner Sonmez
No abstract text is available yet for this article.
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740531/%C3%A2-estimated-time-from-clinical-presentation-to-the-development-of-cirrhosis-in-non-cirrhotic-adult-patients-with-non-alcoholic-fatty-liver-disease
#5
Gerald Y Minuk, Jessica Sanders, Meaghan O'Brien, Julia Uhanova
No abstract text is available yet for this article.
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740530/%C3%A2-albumin-dialysis-with-mars-for-the-treatment-of-anabolic-steroid-induced-cholestasis
#6
Francia C Díaz, Esteban Sáez-González, Salvador Benlloch, Diego Álvarez-Sotomayor, Isabel Conde, Begoña Polo, María García, María Rodríguez, Martín Prieto
:  Background and aims. Steroid-related hepatotoxicity has become one of the most relevant causes of drug induced liver cholestasis. Some patients do not improve after standard medical treatment (SMT) and may therefore require other approaches, like extracorporeal liver support. MATERIAL AND METHODS: We report four cases of patients with pruritus, abnormal liver function tests and biopsy-proven anabolic steroid-induced cholestasis who were unresponsive to SMT. They underwent treatment with albumin dialysis (Molecular Adsorbent Recirculating System -MARS®-)...
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740529/%C3%A2-hepatoportal-sclerosis-related-to-the-use-of-herbals-and-nutritional-supplements-causality-or-coincidence
#7
Fernanda Ferreira Rios, Luiz Antônio Rodrigues de Freitas, Liana Codes, Genario Oliveira Santos Junior, Maria Isabel Schinoni, Raymundo Paraná
:  Introduction and aim. Non-cirrhotic idiopathic portal hypertension (NCIPH), also known as hepatoportal sclerosis (HPS) is a disease of uncertain etiology. However, various pathophysiological mechanisms has been postulated, including chronic or recurrent infections and exposure to drugs or toxins. In this context, it appears to be of multifactorial etiology or resulting from a portal vascular endothelium aggression. It is important to consider whether the use of dietary supplements and herbs can trigger or contribute to the occurance of HPS...
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740528/%C3%A2-pedunculated-hepatic-focal-nodular-hyperplasia
#8
Abdel-Rauf Zeina, Yair Glick
No abstract text is available yet for this article.
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740527/%C3%A2-microrna-146b-regulates-hepatic-stellate-cell-activation-via-targeting-of-klf4
#9
Shanfei Ge, Lunli Zhang, Jianping Xie, Fei Liu, Jinni He, Jinwen He, Xiaowei Wang, Tianxing Xiang
:  Background. We previously identified miR-146b as being up-regulated during the development of hepatic fibrosis using deep sequencing technology and gene expression analysis. However, the roles and related mechanisms of miR-146b in hepatic stellate cells (HSCs), which are involved in fibrogenesis and fibrosis, have not been elucidated. RESULTS: We report that miR-146b expression was increased in TGF-ß1-treated HSCs. TGF- ß1 enhanced α-SMA and COL1A1 protein expression in HSCs and stimulated proliferation of these cells compared with cells transfected with inhibitor NC...
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740526/%C3%A2-percutaneous-shunt-reduction-for-the-management-of-tips-induced-acute-liver-decompensation-a-follow-up-study
#10
Bart De Keyzer, Frederik Nevens, Annouschka Laenen, Sam Heye, Wim Laleman, Chris Verslype, Schalk van der Merwe, Geert Maleux
:  Background and rationale for the study. The purpose of this study was to assess the technical and clinical outcomes of transjugular intrahepatic portosystemic shunt (TIPS) reduction for the management of TIPS-induced acute liver decompensation. Between August 2000 and November 2013, 347 patients underwent a TIPS procedure in the authors' institution; 21/347 (6%) developed post-TIPS acute liver decompensation which was managed using a percutaneous shunt reduction technique. Patient demographics, laboratory tests before and after initial TIPS and TIPS reduction, procedural data and clinical follow-up data were analysed...
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740525/%C3%A2-gnpat-variant-d519g-is-not-associated-with-an-elevated-serum-ferritin-or-iron-removed-by-phlebotomy-in-patients-referred-for-c282y-linked-hemochromatosis
#11
Alexander Levstik, Alan Stuart, Paul C Adams
BACKGROUND: Previous studies in high and low expressors has demonstrated that a variant in the GNPAT gene (D519G, Rs11558492, chromosome 1, exon 11) has been associated with severe iron overload in C282Y homozygotes for hemochromatosis. In this study, a GNPAT variant was assessed prospectively in patients referred for HFE testing over a range of serum ferritin levels. MATERIAL AND METHODS: Consecutive patients sent for HFE testing were studied for the GNPAT variant using a TaqMan kit assay (Life Technologies, Burlington, ON)...
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740524/portal-vein-thrombosis-in-patients-with-cirrhosis-just-a-common-finding-or-a-predictor-of-poor-outcome
#12
Omar D Borjas-Almaguer, Carlos A Cortez-Hernández, Emmanuel I González-Moreno, Francisco J Bosques-Padilla, José A González-González, Aldo A Garza, Juan A Martínez-Segura, Diego García-Compean, Juan V Alejandre-Loya, Jesús García-García, Guillermo Delgado-García, Héctor J Maldonado-Garza
:  Background & Aims. It is unclear whether portal vein thrombosis (PVT) unrelated to malignancy is associated with reduced survival or it is an epiphenomenon of advanced cirrhosis. The objective of this study was to assess clinical outcome in cirrhotic patients with PVT not associated with malignancy and determine its prevalence. MATERIAL AND METHODS: Retrospective search in one center from June 2011 to December 2014. RESULTS: 169 patients, 55 women and 114 men, median age 54 (19-90) years...
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740523/validation-of-prognostic-scores-for-clinical-outcomes-in-cirrhotic-patients-with-acute-variceal-bleeding
#13
Miguel Motola-Kuba, Angélica Escobedo-Arzate, Félix Tellez-Avila, José Altamirano, Nancy Aguilar-Olivos, Alberto González-Angulo, Felipe Zamarripa-Dorsey, Misael Uribe, Norberto C Chávez-Tapia
: Background. The Rockall, Glasgow-Blatchford, and AIMS65 are useful and validated scoring systems for predicting the outcomes of patients with nonvariceal gastrointestinal bleeding. However, there are no validated evidence for using them to predict outcomes on variceal bleeding. The aim of this study was to evaluate and compare the prognostic accuracy of different nonvariceal bleeding scores with other liver-specific scoring systems in cirrhotic patients. MATERIAL AND METHODS: A retrospective multicenter study that included 160 cirrhotic patients with acute variceal bleeding...
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740522/%C3%A2-high-risk-high-reward-an-analysis-of-outcomes-for-candidates-awaiting-hepatic-re-transplantation
#14
Jigesh A Shah, Madhukar S Patel, Johannes R Kratz, James F Markmann, Parsia A Vagefi
:  Background. Liver re-transplantation (re-OLT) remains the only feasible option for patients with graft failure following liver transplantation. Sparse resources and a growing waitlist mandate that available grafts are allocated properly. We studied the differences in patient demographics, characteristics, and survival for those listed for re-OLT in a region with prolonged wait times. MATERIAL AND METHODS: We performed a single-center retrospective study, from 2005 to 2013, of adult candidates listed for liver re-OLT at a tertiary care center within United Network for Organ Sharing (UNOS) region 1...
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740521/predictive-role-blvra-mrna-expression-in-hepatocellular-cancer
#15
Kristy Na Kubícková, Iva Subhanová, Renáta Konícková, Linda Matousová, Petr Urbánek, Hana Parobková, Martin Kupec, Jirí Pudil, Libor Vítek
:  Introduction and aim. Hepatocellular carcinoma (HCC) is the most common primary malignant liver tumor. It is primarily caused by hepatic cirrhosis or chronic viral hepatitis. Hepatic carcinogenesis is associated with increased oxidative stress. Thus, the aim of our study was to assess expression of the genes involved in the homeostasis of oxidative stress in patients with HCC. MATERIAL AND METHODS: The study was performed on 32 patients with primary HCC (verified by liver histology in 29 patients) and 27 control subjects (in 11 subjects, liver histology was available either with no or minimal changes in the liver tissue)...
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740520/%C3%A2-simultaneous-liver-and-kidney-transplantation-in-elderly-patients-outcomes-and-validation-of-a-clinical-risk-score-for-patient-selection
#16
Kristopher P Croome, David D Lee, Justin M Burns, Dana K Perry, Justin H Nguyen, Andrew P Keaveny, Hani M Wadei, C Burcin Taner
:  Introduction and aim. Many transplant programs have expanded eligibility to include patients previously ineligible because of advanced age. Outcomes of simultaneous liver-kidney transplantation (SLK) in recipients with advanced age are not known. MATERIAL AND METHODS: Data from patients undergoing transplantation between 2002 and 2015 were obtained from the UNOS Standard Analysis and Research file. RESULTS: SLK recipients aged ≥ 65 years (N = 677), SLK recipients aged < 65 years (N = 4517), and recipients of liver transplant alone(LTA) aged ≥ 65 years(N = 8495) were compared...
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740519/%C3%A2-chemerin-retinol-binding-protein-4-cytokeratin-18-and-transgelin-2-presence-in-sera-of-patients-with-non-alcoholic-liver-fatty-disease
#17
Agnieszka Zwolak, Agnieszka Szuster-Ciesielska, Jadwiga Daniluk, Justyna Semeniuk, Martyna Kandefer-Szerszen
:  Background. Chemerin and retinol binding protein-4 (RBP-4) are adipokines which may play a role in the progression of NAFLD. It has been also suggested that cytokeratin-18 (CK-18) could be a marker of hepatocyte caspase-directed death while transgelin-2 production could reflect stage of liver fibrosis. The aim of this study was to evaluate the level of the above adipokines in sera of patients with NAFLD and determine the relation between the level of transgelin-2 and fibrosis-4 index (FIB-4)...
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740518/%C3%A2-most-overweight-and-obese-indian-children-have-nonalcoholic-fatty-liver-disease
#18
Sunil V Pawar, Vinay G Zanwar, Ajay S Choksey, Ashok R Mohite, Samit S Jain, Ravindra G Surude, Qais Q Contractor, Pravin M Rathi, Ravi U Verma, Premlata K Varthakavi
:  Background and rationale. Nonalcoholic fatty liver disease (NAFLD) is the most common cause of pediatric liver disease in western countries. Its prevalence in Indian subcontinent is not well studied. MATERIAL AND METHODS: In a school based cross sectional study we have screened overweight and obese children in the age group of 11 to 15 years for NAFLD. Ultrasonography, elevated serum transaminases, fibroscan were used for defining NAFLD. Dietary habits, blood pressure, serum lipid profile, blood counts and insulin resistance were recorded...
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740517/%C3%A2-frequency-of-hepatitis-c-virus-infection-in-a-single-institution-in-mexico-with-a-focus-on-birth-cohort-population
#19
Héctor Baptista-González, Victor M Noffal-Nuño, Nahum Méndez-Sánchez
:  Background and rationale for the study. The generation of people born before 1965 is a high-risk group for developing chronic hepatitis C virus (HCV) infection. AIM: To report the experience on single institution of HCV infection under birth-cohort or baby boomers effect. MATERIAL AND METHODS: We used a cross-sectional design of consecutive subjects older than 18 years referred for serological evaluation for anti-HCV and detection of HCV RNA...
November 2016: Annals of Hepatology
https://www.readbyqxmd.com/read/27740516/daclatasvir-and-peginterferon-ribavirin-for-black-african-american-and-latino-patients-with-hcv-infection
#20
Maribel Rodriguez-Torres, Eric Lawitz, Bienvenido Yangco, Lennox Jeffers, Steven-Huy Han, Paul J Thuluvath, Vinod Rustgi, Stephen Harrison, Reem Ghalib, John M Vierling, Velimir Luketic, Philippe J Zamor, Natarajan Ravendhran, Timothy R Morgan, Brian Pearlman, Christopher O'Brien, Hicham Khallafi, Nikolaos Pyrsopoulos, George Kong, Fiona McPhee, Philip D Yin, Eric Hughes, Michelle Treitel
:  Background. Patient race and ethnicity have historically impacted HCV treatment response. This phase 3 study evaluated daclatasvir with peginterferon-alfa-2a/ribavirin (pegIFN alfa-2a/RBV) in treatment-naive black/African American (AA), Latino, and white non-Latino patients with chronic HCV genotype 1 infection. MATERIAL AND METHODS: In this single-arm, open-label study, 246 patients received daclatasvir plus pegIFN alfa-2a and weight-based RBV. Patients with an extended rapid virologic response (eRVR; undetectable HCV-RNA at treatment weeks 4 and 12) received 24 weeks of treatment; those without eRVR received an additional 24 weeks of treatment with pegIFN alfa-2a/RBV...
November 2016: Annals of Hepatology
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