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Anatomical Science International

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https://www.readbyqxmd.com/read/27888476/histological-detection-of-dynamic-glial-responses-in-the-dysmyelinating-tabby-jimpy-mutant-brain
#1
Masanao Ikeda, M Ibrahim Hossain, Li Zhou, Masao Horie, Kazuhiro Ikenaka, Arata Horii, Hirohide Takebayashi
Oligodendrocytes (OLs) are glial cells that form myelin sheaths surrounding the axons in the central nervous system (CNS). Jimpy (jp) mutant mice are dysmyelinating disease models that show developmental abnormalities in myelinated OLs in the CNS. The causative gene in jp mice is the proteolipid protein (PLP) located on the X chromosome. Mutations in the jp allele result in exon 5 skipping and expression of abnormal PLP containing a C-terminal frame shift. Many lines of evidence suggest that abnormal PLP in OLs results in endoplasmic reticulum (ER) stress and cell death...
November 25, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27832478/planimetric-correlation-between-the-submandibular-glands-and-the-pancreas-a-postmortem-ductographic-study
#2
Bojan V Stimec, Zoran Rakocevic, Dejan Ignjatovic, Jean H D Fasel
The salivary glands and pancreas have comparable anatomic and antigenic properties and can share common pathogenetic mechanisms involving toxic or autoimmune processes. The aim of this study is to assess the correlation in size between the normal submandibular glands and the pancreas. The study was based on human autopsy specimens of the pancreas, neck and oral base from 22 adults, both sexes (mean age, 57.9 years). The pancreatic and submandibular ducts were injected with a contrast medium, and the area of the salivary and pancreatic glandular ductograms was measured with the aid of software for quantification of visual information...
November 10, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27830440/surgical-relevance-of-the-lateral-costotransverse-ligament-in-relation-to-the-dorsal-root-ganglion
#3
Anthony V D'Antoni, Peter G Collin, Rachel A Graham, Helena M Kennedy, Tatiana Ndjatou, Pamela Perez, R Shane Tubbs, Marios Loukas, Piotr B Kozlowski, Estomith P Mtui
The lateral costotransverse ligament, a short band that stabilizes the costovertebral joint, is found in close proximity to the dorsal root ganglion. This ligament is an important surgical landmark during tumor resections or nerve blocks in the paravertebral space. The purpose of this study was to quantitatively and qualitatively describe the morphology of the lateral costotransverse ligament and its relation to the dorsal root ganglion at all levels of the thoracic spine. The thoracic spines of eight embalmed cadavers were dissected bilaterally...
November 9, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27822589/regulation-of-lipid-metabolism-via-a-connection-between-the-endoplasmic-reticulum-and-lipid-droplets
#4
REVIEW
Michitaka Suzuki
Lipid droplets (LDs) are ubiquitous organelles that store and supply lipids to regulate cellular lipid homeostasis. Fatty acids are packaged as triglyceride and cholesterol ester into endoplasmic reticulum (ER) membranes to synthesize LDs. Cytosolic LDs move dynamically and interact with organelles, including other LDs. In this process, functional proteins for metabolism are also transferred to LDs. In this review, I focus on interactions between the ER and LDs related to lipid metabolism.
November 7, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27785745/novel-scanning-electron-microscopy-methods-for-analyzing-the-3d-structure-of-the-golgi-apparatus
#5
REVIEW
Daisuke Koga, Tatsuo Ushiki, Tsuyoshi Watanabe
The structure of the Golgi apparatus has been extensively examined by light and electron microscopy, but details of its three-dimensional (3D) structure have remained unclear because of the technical limitations of conventional microscopy techniques. To overcome this problem, we have developed several novel scanning electron microscopy (SEM) methods for observing the 3D structure of subcellular organelles including the Golgi apparatus: (1) an osmium maceration method that facilitates SEM observation of membranous organelles, including the Golgi apparatus, by selectively removing soluble cytoplasmic proteins, (2) an osmium impregnation/maceration method that combines an osmium impregnation method with the osmium maceration method to determine the polarity of the Golgi apparatus by SEM, (3) a correlative light and SEM method that combines a cryosectioning technique with the osmium maceration method to enable correlation of the immunocytochemical distribution of molecules with the 3D ultrastructure of the Golgi apparatus, and (4) array tomography based on the systematic collection and integration of SEM images of serial ultrathin sections on glass slides for revealing the 3D ultrastructure of the entire Golgi apparatus...
October 26, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27757809/a-novel-cadaveric-study-of-the-morphometry-of-the-serratus-anterior-muscle-one-part-two-parts-three-parts-four
#6
Alexandra Louise Webb, Elizabeth O'Sullivan, Maria Stokes, Sarah Mottram
The serratus anterior is portrayed as a homogeneous muscle in textbooks and during functional activities and rehabilitation exercises. It is unclear whether the serratus anterior is composed of subdivisions with distinctive morphology and functions. The purpose of this study was to determine whether the serratus anterior could be subdivided into different structural parts on the basis of its segmental architectural parameters. Eight formalin-embalmed serratus anterior muscles were dissected and the attachments of each fascicle documented...
October 18, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27730491/the-significance-of-the-supratrochlear-aperture-sta-in-elbow-range-of-motion-an-anatomical-study
#7
Robert Ndou
Assessment of the range of motion at a joint is among the methods employed by orthopedic surgeons and physiotherapists to determine courses of therapy and joint recovery. Females tend to have a greater range of motion at the elbow joint than males. In the present case-control study, the elbow extension angle was compared between males and females with and without the supratrochlear aperture. A total of 453 dry humeri and their corresponding ulnae were included in the study, and elbow extension angle was measured using a goniometer...
October 11, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27730490/the-possibilities-of-studying-human-embryos-and-foetuses-using-micro-ct-a-technical-note
#8
Kateřina Vymazalová, Lenka Vargová, Tomáš Zikmund, Jozef Kaiser
The purpose of the study was to discover a way to study the internal structure and evolution of human embryos noninvasively. The human embryo was stained with phosphotungstic acid solution (PTA) in ethanol (EPTA) and scanned using a micro computed tomography (micro-CT) scanner. Using appropriate software, a three-dimensional image of the embryo was created, which could be further exploited. The methodology described could be used for the non-destructive examination of the internal structure of the human embryo, and the resulting data can be used as a resource for medical students, gynaecologists, and paediatricians...
October 11, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27718210/renin-angiotensin-system-in-vertebrates-phylogenetic-view-of-structure-and-function
#9
Hiroko Nishimura
Renin substrate, biological renin activity, and/or renin-secreting cells in kidneys evolved at an early stage of vertebrate phylogeny. Angiotensin (Ang) I and II molecules have been identified biochemically in representative species of all vertebrate classes, although variation occurs in amino acids at positions 1, 5, and 9 of Ang I. Variations have also evolved in amino acid positions 3 and 4 in some cartilaginous fish. Angiotensin receptors, AT1 and AT2 homologues, have been identified molecularly or characterized pharmacologically in nonmammalian vertebrates...
October 7, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27714583/insights-from-extracellular-matrix-studies-in-the-hypothalamus-structural-variations-of-perineuronal-nets-and-discovering-a-new-perifornical-area-of-the-anterior-hypothalamus
#10
Noriko Horii-Hayashi, Takayo Sasagawa, Mayumi Nishi
The hypothalamus controls metabolism, stress responses, and instinctive behaviors for individual survival and species preservation. Recent studies suggest that hypothalamic neurons retain plasticity throughout adulthood, which enables these neurons to respond to various kinds of changes in environment, nutrients, and fluctuating hormones. One of the mechanisms underlying the regulation of neural plasticity is the formation of a stable extracellular matrix (ECM) structure called perineuronal nets (PNNs). PNNs are large aggregates of heterogeneous ECM molecules such as chondroitin sulfate proteoglycans (CSPGs), hyaluronan, their link proteins, and tenascin-R...
October 6, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27659947/earlobe-like-peritoneal-appendage-near-the-angle-of-his-a-useful-landmark-for-demarcating-the-lateral-margin-of-the-gastric-cardia
#11
Kanji Hirashima, Fengming Yue, Daihachiro Tomotsune, Katsunori Sasaki
The gastric cardia-the small area around the cardiac orifice including the abdominal esophagus-is an important target area for abdominal and thoracic surgeries, especially for laparoscopic procedures. In this study of 28 cadavers, a peritoneal earlobe-like appendage near the angle of His was identified as a useful indicator of the lateral margin of the abdominal esophagus, which is otherwise obscure because the peritoneum continues to the diaphragm without definite demarcation of this margin. This structure, which appears equivalent to the epiploic appendages, was commonly found to be present (in 22/28, 78...
September 22, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27631096/low-origin-of-the-radial-artery-a-case-study-including-a-review-of-literature-and-proposal-of-an-embryological-explanation
#12
Grzegorz Wysiadecki, Michał Polguj, Robert Haładaj, Mirosław Topol
A low origin of the radial artery is a rare anatomical variation, with the incidence estimated at 0.2 %. This report presents a previously unrecorded case of an unusual distal origin of the radial artery, co-occurring with a double recurrent radial artery. The radial artery arose under the pronator teres muscle, 76 mm below the intercondylar line of the humerus. After emerging from under the tendon of the pronator teres muscle, the radial artery took a typical course and terminated in the deep palmar arch...
September 15, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27631095/ultrastructural-histometric-evidence-for-expansion-of-the-sustentacular-cell-envelope-in-response-to-hypersecretion-of-adrenal-chromaffin-cells-in-mice
#13
Sawetree Pakkarato, Wipawee Thoungseabyoun, Apussara Tachow, Atsara Rawangwong, Yoshiteru Kagawa, Yuji Owada, Hisatake Kondo, Wiphawi Hipkaeo
In our previous immuno-light microscopic study with an antibody for fatty acid binding protein of type 7 or brain type (FABP-7, B-FABP), the adrenomedullary sustentacular cells were revealed to have secondary processes that present faint immunostaining and an ill-defined sheet-like appearance, in addition to the well-recognized primary processes that present distinct immunostaining and a fibrous appearance. The secondary processes were regarded as corresponding to known ultrastructural profiles of sustentacular cells with a thickness of less than 0...
September 15, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27629485/giovanni-battista-morgagni-1682-1771-father-of-pathologic-anatomy-and-pioneer-of-modern-medicine
#14
Sanjib Kumar Ghosh
Giovanni Battista Morgagni (1682-1771) was an Italian anatomist who introduced the anatomo-clinical concept in medicine and established anatomy as the instrument to identify the seat and etiology of any disease. He was professor of anatomy at the prestigious University of Padua for more than 50 years. His first documented text in anatomy, Adversaria Anatomica was published in three volumes between 1706 and 1719. His accurate anatomical descriptions of human organs enhanced his reputation as the most famous anatomist of Europe during that period...
September 14, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27618818/reevaluation-of-the-superior-radial-collateral-artery-in-the-human-upper-arm
#15
Koichiro Ichimura, Shota Kinose, Yuto Kawasaki, Kota Kato, Tatsuo Sakai
The superior radial collateral artery (SRCA) was described in well-established anatomy textbooks published in the 1800s. According to those textbooks, the SRCA originates from the brachial artery, passes transversely between the coracobrachialis and the humerus, and distributes to the most distal portion of the deltoid. The SRCA is not listed in the international standard on anatomical terminology, Terminologia Anatomica, or in modern anatomy textbooks. In the present study, we reevaluated the anatomical features of the SRCA by cadaveric dissection...
September 12, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27614971/roles-of-organic-anion-transporters-oats-in-renal-proximal-tubules-and-their-localization
#16
Naoyuki Otani, Motoshi Ouchi, Keitaro Hayashi, Promsuk Jutabha, Naohiko Anzai
Organic anions (OAs) are secreted in renal proximal tubules in two steps. In the first step, OAs are transported from the blood through basolateral membranes into proximal tubular cells. The prototypical substrate for renal organic anion transport systems, para-aminohippurate (PAH), is transported across basolateral membranes of proximal tubular cells via OAT1 (SLC22A6) and OAT3 (SLC22A8) against an electrochemical gradient in exchange for intracellular dicarboxylates. In the second step, OAs exit into urine through apical membranes of proximal tubules...
September 10, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27590897/tissue-and-cell-specific-localization-of-galectins-%C3%AE-galactose-binding-animal-lectins-and-their-potential-functions-in-health-and-disease
#17
Junko Nio-Kobayashi
Fifteen galectins, β-galactose-binding animal lectins, are known to be distributed throughout the body. We herein summarize current knowledge on the tissue- and cell-specific localization of galectins and their potential functions in health and disease. Galectin-3 is widely distributed in epithelia, including the simple columnar epithelium in the gut, stratified squamous epithelium in the gut and skin, and transitional epithelium and several regions in nephrons in the urinary tract. Galectin-2 and galectin-4/6 are gut-specific, while galectin-7 is found in the stratified squamous epithelium in the gut and skin...
September 2, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27586453/morphology-and-morphometry-of-the-caudate-lobe-of-the-liver-in-two-populations
#18
Mandeep Gill Sagoo, R Claire Aland, Edward Gosden
The caudate lobe of the liver has portal blood supply and hepatic vein drainage independent of the remainder of the liver and may be differentially affected in liver pathologies. Ultrasonographic measurement of the caudate lobe can be used to generate hepatic indices that may indicate cirrhosis. This study investigated the relationship of metrics of the caudate lobe and other morphological features of human livers from a northwest Indian Punjabi population (n = 50) and a UK Caucasian population (n = 25), which may affect the calculation of hepatic indices...
September 1, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27324639/pleiotropic-and-retinoprotective-functions-of-pacap
#19
REVIEW
Seiji Shioda, Fumiko Takenoya, Nobuhiro Wada, Takahiro Hirabayashi, Tamotsu Seki, Tomoya Nakamachi
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 27- or 38-amino acid neuropeptide, which belongs to the vasoactive intestinal polypeptide/glucagon/secretin family. PACAP and its three receptor subtypes are expressed in neural tissues of the eye, including the retina, cornea and lacrimal gland, and PACAP is known to exert pleiotropic effects throughout the central nervous system. This review provides an overview of current knowledge regarding the cell protective effects, mechanisms of action and therapeutic potential of PACAP in response to several types of eye injury...
September 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27147443/re-analysis-on-geometric-energy
#20
LETTER
Kenichi Makino, Kenta Funayama, Yuji Ikegaya
No abstract text is available yet for this article.
September 2016: Anatomical Science International
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