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Hepatobiliary & Pancreatic Diseases International: HBPD INT

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https://www.readbyqxmd.com/read/28603104/combined-cavo-atrial-thrombectomy-and-hepatectomy-in-hepatocellular-carcinoma
#1
Julian Tsang, Albert Chan, Kenneth Chok, Flora Tsang, Chung Mau Lo
No abstract text is available yet for this article.
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603103/orthotopic-liver-transplantation-from-a-donor-with-schistosoma-japonicum
#2
Bo Peng, Xing-Guo She, Ke Cheng, Hong Liu, Ying Niu, Ying-Zi Ming
No abstract text is available yet for this article.
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603102/a-clinical-analysis-of-acute-pancreatitis-in-pregnancy
#3
Ben-Lan Yin, Xiao-Dong Fu
No abstract text is available yet for this article.
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603101/pancreatic-head-excavation-for-tissue-diagnosis-may-reduce-unnecessary-pancreaticoduodenectomies-in-the-setting-of-chronic-pancreatitis
#4
Alessandro Fancellu, Giorgio C Ginesu, Claudio F Feo, Maria L Cossu, Marco Puledda, Antonio Pinna, Alberto Porcu
BACKGROUND: The necessity to obtain a tissue diagnosis of cancer prior to pancreatic surgery still remains an open debate. In fact, a non-negligible percentage of patients undergoing pancreaticoduodenectomy (PD) for suspected cancer has a benign lesion at final histology. We describe an approach for patients with diagnostic uncertainty between cancer and chronic pancreatitis, with the aim of minimizing the incidence of PD for suspicious malignancy finally diagnosed as benign disease. METHODS: Eighty-eight patients (85...
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603100/total-closure-of-pancreatic-section-for-end-to-side-pancreaticojejunostomy-decreases-incidence-of-pancreatic-fistula-in-pancreaticoduodenectomy
#5
Yu-Ling Sun, Ya-Lei Zhao, Wen-Qi Li, Rong-Tao Zhu, Wei-Jie Wang, Jian Li, Shuai Huang, Xiu-Xian Ma
BACKGROUND: Postoperative pancreatic fistula (POPF) is a serious complication and results in prolonged hospitalization and high mortality. The present study aimed to evaluate the safety and effectiveness of total closure of pancreatic section for end-to-side pancreaticojejunostomy in pancreaticoduodenectomy (PD). METHODS: This was a prospective randomized clinical trial comparing the outcomes of PD between patients who underwent total closure of pancreatic section for end-to-side pancreaticojejunostomy (Group A) vs those who underwent conventional pancreaticojejunostomy (Group B)...
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603099/using-receiver-operating-characteristic-curves-to-evaluate-the-diagnostic-value-of-the-combination-of-multislice-spiral-ct-and-alpha-fetoprotein-levels-for-small-hepatocellular-carcinoma-in-cirrhotic-patients
#6
Guang-Sheng Jia, Guang-Long Feng, Jin-Ping Li, Hai-Long Xu, Hui Wang, Yi-Peng Cheng, Lin-Lin Yan, Hui-Jie Jiang
BACKGROUND: The various combination of multiphase enhancement multislice spiral CT (MSCT) makes the diagnosis of a small hepatocellular carcinoma (sHCC) on the background of liver cirrhosis possible. This study was to explore whether the combination of MSCT enhancement scan and alpha-fetoprotein (AFP) level could increase the diagnostic efficiency for sHCC. METHODS: This study included 35 sHCC patients and 52 cirrhotic patients without image evidence of HCC as a control group...
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603098/comparison-of-efficacy-of-folic-acid-and-silymarin-in-the-management-of-antiepileptic-drug-induced-liver-injury-a-randomized-clinical-trial
#7
Masoumeh Asgarshirazi, Mamak Shariat, Mahdi Sheikh
BACKGROUND: Liver injury associated with antiepileptic drugs accounts for a large proportion of drug-induced liver injuries (DILI) in children. Although withdrawal of the causative agent is the only proved treatment for DILI, in some clinical situations it is not possible. Recent studies have reported promising results of using hepatoprotective drugs with antioxidant actions for the management of DILI. This study aimed to evaluate the efficacy of folic acid versus silymarin treatment in relation to decreasing liver enzymes in patients with DILI due to antiepileptic therapy...
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603097/circulating-autoantibodies-to-endogenous-erythropoietin-are-associated-with-chronic-hepatitis-c-virus-infection-related-anemia
#8
Aristotelis Tsiakalos, Theoharis Voumvas, Alexandros Psarris, Christina K Oikonomou, Dimitrios C Ziogas, Ioannis Ketikoglou, Grigorios Hatzis, Nikolaos V Sipsas
BACKGROUND: Chronic hepatitis C virus (HCV) infection is associated with autoimmune phenomena and is often complicated by anemia. Circulating autoantibodies to endogenous erythropoietin (anti-EPO) have been detected in patients with chronic viral infections and were correlated to anemia. The present study aimed to determine anti-EPO prevalence in patients with chronic HCV infection and investigate its possible association with anemia. METHODS: Ninety-three consecutive patients (62 males and 31 females) with chronic HCV infection, who had never received antiviral therapy or recombinant EPO, were enrolled in the study...
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603096/patients-with-early-recurrence-of-hepatocellular-carcinoma-have-poor-prognosis
#9
Tomoki Kobayashi, Hiroshi Aikata, Tsuyoshi Kobayashi, Hideki Ohdan, Koji Arihiro, Kazuaki Chayama
BACKGROUND: Early recurrence (ER) after hepatic resection (HR) is a poor prognostic factor for patients with hepatocellular carcinoma (HCC). This study aimed to identify the clinicopathological features, outcomes, and risk factors for ER after HR for small HCC in order to clarify the reasons why ER is a worse recurrence pattern. METHODS: We retrospectively examined 130 patients who underwent HR for small HCC (≤30 mm). Recurrence was classified into ER (<2 years) and late recurrence (LR) (≥2 years)...
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603095/traditional-surgical-planning-of-liver-surgery-is-modified-by-3d-interactive-quantitative-surgical-planning-approach-a-single-center-experience-with-305-patients
#10
Xue-Dong Wang, Hong-Guang Wang, Jun Shi, Wei-Dong Duan, Ying Luo, Wen-Bin Ji, Ning Zhang, Jia-Hong Dong
BACKGROUND: Decision making and surgical planning are to achieve the precise balance of maximal removal of target lesion, maximal sparing of functional liver remnant volume, and minimal surgical invasiveness and therefore, crucial in liver surgery. The aim of this prospective study was to validate the accuracy and predictability of 3D interactive quantitative surgical planning approach (IQSP), and to evaluate the impact of IQSP on traditional surgical plans based on 2D images. METHODS: A total of 305 consecutive patients undergoing hepatectomy were included in this study...
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603094/liver-transplantation-in-patients-with-incidental-hepatocellular-carcinoma-cholangiocarcinoma-and-intrahepatic-cholangiocarcinoma-a-single-center-experience
#11
Mohammed Elshamy, Naftali Presser, Abdulrahman Y Hammad, Daniel J Firl, Christopher Coppa, John Fung, Federico N Aucejo
BACKGROUND: Reports of liver transplantation (LT) in patients with mixed hepatocellular carcinoma/cholangiocarcinoma (HCC/CC) and intrahepatic cholangiocarcinoma (ICC) are modest and have been mostly retrospective after pathological categorization in the setting of presumed HCC. Some studies suggest that patients undergoing LT with small and unifocal ICC or mixed HCC/CC can achieve about 40%-60% 5-year post-transplant survival. The study aimed to report our experience in patients undergoing LT with explant pathology revealing HCC/CC and ICC...
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603093/role-of-18-f-fludeoxyglucose-positron-emission-tomography-in-the-selection-of-liver-transplantation-candidates-in-patients-with-hepatocellular-carcinoma
#12
Yu-Fu Ye, Wei Wang, Ting Wang, Jun Yu, Lei Geng, Song-Feng Yu, Sheng Yan, Shu-Sen Zheng
BACKGROUND: The Milan criteria are widely accepted among many centers. However, patients with hepatocellular carcinoma beyond the Milan criteria might still benefit from liver transplantation (LT) when tumor itself is not aggressive. [(18)F] fluorodeoxyglucose positron emission tomography/computed tomography imaging could provide useful information of tumor behaviors, which is helpful to predict the prognosis for many tumors. METHOD: In order to determine its role in candidate selection for LT, we therefore retrospectively analyzed 103 recipients with preoperative positron emission tomography (PET) findings...
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603092/crosstalk-of-liver-immune-cells-and-cell-death-mechanisms-in-different-murine-models-of-liver-injury-and-its-clinical-relevance
#13
Hilal Ahmad Khan, Muhammad Zishan Ahmad, Junaid Ali Khan, Muhammad Imran Arshad
BACKGROUND: Liver inflammation or hepatitis is a result of pluripotent interactions of cell death molecules, cytokines, chemokines and the resident immune cells collectively called as microenvironment. The interplay of these inflammatory mediators and switching of immune responses during hepatotoxic, viral, drug-induced and immune cell-mediated hepatitis decide the fate of liver pathology. The present review aimed to describe the mechanisms of liver injury, its relevance to human liver pathology and insights for the future therapeutic interventions...
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603091/gemcitabine-based-combination-therapy-compared-with-gemcitabine-alone-for-advanced-pancreatic-cancer-a-meta-analysis-of-nine-randomized-controlled-trials
#14
Shui-Fang Jin, Zhao-Kun Fan, Lei Pan, Li-Ming Jin
BACKGROUND: Pancreatic cancer is one of the most aggressive malignancies and chemotherapy is an effective strategy for advanced pancreatic cancer. Gemcitabine (GEM) is one of first-line agents. However, GEM-based combination therapy has shown promising efficacy in patients with advanced pancreatic cancer. This meta-analysis aimed to compare the efficacy and safety of GEM-based combination therapy versus GEM alone in the treatment of advanced pancreatic cancer. DATA SOURCES: A comprehensive search of literature was performed using PubMed, EMBASE, Web of Science and Cochrane Central Register of Controlled Trials...
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28603090/better-preoperative-planning-improves-liver-resection-outcomes
#15
Trevor W Reichman
No abstract text is available yet for this article.
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28381388/pancreaticoduodenectomy-for-borderline-resectable-pancreatic-head-cancer-with-a-modified-artery-first-approach-technique
#16
Min Wang, Hang Zhang, Feng Zhu, Feng Peng, Xin Wang, Ming Shen, Ren-Yi Qin
BACKGROUND: The treatment of borderline resectable pancreatic head cancer (BRPHC) is still controversial and challenging. The artery-first approaches are described to be the important options for the early determination. Whether these approaches can achieve an increase R0 rate, better bleeding control and increasing long-term survival for BRPHC are still controversial. We compared a previously reported technique, a modified artery-first approach (MAFA), with conventional techniques for the surgical treatment of BRPHC...
April 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28381387/long-term-outcome-of-patients-with-chronic-pancreatitis-treated-with-micronutrient-antioxidant-therapy
#17
Sukitha Namal Rupasinghe, Ajith K Siriwardena
BACKGROUND: Micronutrient antioxidant therapy did not relieve pain in a European randomized trial of patients with chronic pancreatitis without malnutrition. However, intervention was undertaken only for 6 months leaving unanswered the question of whether long-term antioxidant therapy may modulate chronic pancreatitis. The aim of this study is to assess the outcome of long-term use of micronutrient antioxidant therapy in patients with chronic pancreatitis. METHODS: This is a single center clinical cohort report of patients with chronic pancreatitis prescribed micronutrient antioxidant therapy and followed for up to 10 years...
April 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28381386/high-grade-pancreatic-intraepithelial-lesions-prevalence-and-implications-in-pancreatic-neoplasia
#18
Jean R Park, Feng Li, Veeral M Oza, Brett C Sklaw, Kevin M Cronley, Michael Wellner, Benjamin Swanson, Somashekar G Krishna
BACKGROUND: High-grade pancreatic intraepithelial neoplasia (PanIN-3), a precursor of pancreatic ductal adenocarcinoma (PDAC), is not universally detected in resected pancreatic neoplasms. We sought to determine the prevalence and prognostic relevance of PanIN-3 lesions in primary surgical resections of PDACs and intraductal papillary mucinous neoplasms (IPMNs). METHODS: A retrospective review of a tertiary care center pathology database (1/2000-6/2014) was performed...
April 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28381385/hida-scan-for-functional-gallbladder-disorder-ensure-that-you-know-how-the-scan-was-done
#19
Naeem Goussous, Hadia Maqsood, Ethan Spiegler, Gopal C Kowdley, Steven C Cunningham
BACKGROUND: Despite the increasing use of fatty meal (FM) as a substitute for cholecystokinin (CCK) in pain reproduction during hepato-imino-diacetic acid (HIDA) scan in functional gallbladder disorder, there are no studies comparing the differences between CCK and FM. The present study was to compare the efficacy of FM in comparison of CCK in FGBD application. METHODS: Patients undergoing HIDA scans from August 2013 to May 2014 were divided into two groups: those undergoing CCK-stimulated HIDA scan versus FM-stimulated HIDA scan...
April 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28381384/novel-hbv-mutations-and-their-value-in-predicting-efficacy-of-conventional-interferon
#20
Da-Xian Wu, Xiao-Yu Fu, Guo-Zhong Gong, Ke-Wei Sun, Huan-Yu Gong, Ling Wang, Juan Wu, De-Ming Tan
BACKGROUND: Accumulating studies assessing the impacts of hot spot mutations on conventional interferon (IFN) efficacy come to discrepant conclusions; studies regarding the mutations in S and RT regions are also unclear. The present study aimed to evaluate the impacts of HBV mutations on the efficacy of conventional IFN. METHODS: A total of 126 patients who received conventional IFN treatment for 48 weeks were enrolled. Biochemical and serological parameters were routinely tested...
April 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
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