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Hepatobiliary & Pancreatic Diseases International: HBPD INT

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https://www.readbyqxmd.com/read/30237091/preoperative-risk-factors-for-early-recurrence-in-patients-with-resectable-pancreatic-ductal-adenocarcinoma-after-curative-intent-surgical-resection
#1
Nam Hee Kim, Hong Joo Kim
BACKGROUND: Postoperative early recurrence (ER) in patients with pancreatic ductal adenocarcinoma (PDAC) is frequently encountered after curative intent surgery. Nonetheless, clinical significance and risk factors of ER after surgery for PDAC have not been extensively investigated. The aim of this study was to determine preoperative risk predictors for ER in patients with PDAC after upfront surgery. METHODS: Eighty-one consecutive patients with PDAC who underwent curative intent surgical resection at Kangbuk Samsung Hospital between January 2004 and May 2015 were enrolled...
September 7, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30228025/detecting-accidental-punctures-and-lacerations-during-cholecystectomy-in-large-datasets-two-methods-of-analysis
#2
Artem Shmelev, Anne M Sill, Gopal C Kowdley, Juan A Sanchez, Steven C Cunningham
BACKGROUND: After the Institute of Medicine (IOM) report To Err Is Human highlighted the impact of medical errors, the Agency for Healthcare Research and Quality (AHRQ) developed Patient-Safety Indicators (PSI) to improve quality by identifying potential inpatient safety problems. PSI-15 was created to study accidental punctures and lacerations (APL), but PSI-15 may underestimate APLs in populations of patients. This study compares PSI-15 with a more inclusive approach using a novel composite of secondary diagnostic and procedural codes...
September 7, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30220522/prediction-of-rat-liver-transplantation-outcomes-using-energy-metabolites-measured-by-microdialysis
#3
Qi Pan, Ying Cheng, Zi-Gong Shao, An-Yin Wang, Yong-Feng Liu
BACKGROUND: Warm ischemia jeopardizes graft quality and recipient survival in donation after cardiac death (DCD) transplantation. Currently, there is no system to objectively evaluate the liver quality from DCD. The present study tried to use energy metabolites to evaluate the donor liver quality. METHODS: We divided 195 Sprague-Dawley rats into five groups: the control (n = 39), warm ischemic time (WIT) 15 min (n = 39), WIT 30 min (n = 39), WIT 45 min (n = 39), and WIT 60 min (n = 39) groups...
September 7, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30205926/the-changes-of-intraoperative-body-temperature-in-adult-liver-transplantation-a-retrospective-study
#4
Ying Sun, Lili Jia, Wenli Yu, Hongli Yu, Mingwei Sheng, Hongyin Du
BACKGROUND: Body temperature is poorly regulated in patients with end-stage liver disease. Due to the prolonged surgery time and anhepatic time as well as the complex surgical procedures performed in liver transplantation, the body temperature fluctuates greatly. This study investigated the effect of intraoperative body temperature fluctuations on the prognosis of liver recipients. METHODS: The body temperatures of liver recipients recorded from the induction of anesthesia (T0 ) until the end of surgery (T14 ) were retrieved...
August 29, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30201411/il-37b-suppresses-epithelial-mesenchymal-transition-in-hepatocellular-carcinoma-by-inhibiting-il-6-stat3-signaling
#5
Xing-Yu Pu, Dao-Feng Zheng, Ai Shen, Hai-Tao Gu, Xu-Fu Wei, Tong Mou, Jian-Bo Zhang, Rui Liu
BACKGROUND: Interleukin-37b (IL-37b), a vital negative regulator of the innate immune system, has been reported to be a tumor inhibitor in different type of cancers. However, little is known about the relationship between IL-37b and hepatocellular carcinoma (HCC). The present study aimed to investigate the potential roles of IL-37b in HCC progression. METHODS: Subjects (n = 237) were recruited, and serum IL-37b was measured using ELISA. The tumor-suppressive capacity and underlying mechanisms of IL-37b in HCC were investigated in vitro and in vivo...
August 29, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30197163/the-microbiology-of-infected-pancreatic-necrosis
#6
Nicholas G Mowbray, Bassam Ben-Ismaeil, Mohammed Hammoda, Guy Shingler, Bilal Al-Sarireh
BACKGROUND: Acute pancreatitis (AP) continues to cause significant morbidity and mortality, especially when it leads to infected pancreatic necrosis (IPN). Modern treatment of IPN frequently involves prolonged courses of antibiotics in combination with minimally invasive therapies. This study aimed to update the existing evidence base by identifying the pathogens causing IPN and therefore aid future selection of empirical antibiotics. METHODS: Clinical data, including microbiology results, of consecutive patients with IPN undergoing minimally invasive necrosectomy at our institution between January 2009 and July 2016 were retrospectively reviewed...
August 29, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30170983/transit-time-ultrasound-perivascular-flow-probe-technology-is-superior-to-mr-imaging-on-hepatic-blood-flow-measurement-in-a-porcine-model
#7
Mohamed Bekheit, Chloe Audebert, Petru Bucur, Hans Adriaensen, Emilie Bled, Mylène Wartenberg, Irene Vignon-Clementel, Eric Vibert
BACKGROUND: The hepatic hemodynamics is an essential parameter in surgical planning as well as in various disease processes. The transit time ultrasound (TTUS) perivascular flow probe technology is widely used in clinical practice to evaluate the hepatic inflow, yet invasive. The phase-contrast-MRI (PC-MRI) is not invasive and potentially applicable in assessing the hepatic blood flow. In the present study, we compared the hepatic inflow rates using the PC-MRI and the TTUS probe, and evaluated their predictive value of post-hepatectomy adverse events...
August 8, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30126828/predictors-of-long-term-survival-after-pancreaticoduodenectomy-for-peri-ampullary-adenocarcinoma-a-retrospective-study-of-5-year-survivors
#8
Ayman El Nakeeb, Mohamed El Sorogy, Helmy Ezzat, Rami Said, Mohamed El Dosoky, Mohamed Abd El Gawad, Ahmed M Elsabagh, Ehab El Hanafy
BACKGROUND: Pancreaticoduodenectomy (PD) is the standard curative treatment for periampullary tumors. The aim of this study is to report the incidence and predictors of long-term survival (≥ 5 years) after PD. METHODS: This study included patients who underwent PD for pathologically proven periampullary adenocarcinomas. Patients were divided into 2 groups: group (I) patients who survived less than 5 years and group (II) patients who survived ≥ 5 years...
August 7, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30126827/self-expandable-metal-stents-for-choledocholithiasis-in-billroth-ii-gastrectomy-patients
#9
Min-Gui Han, Eunae Cho, Chang-Hwan Park, Chung-Hwan Jun, Seon-Young Park
BACKGROUND: Efficient ampullary intervention is essential for endoscopic retrograde cholangiopancreatography (ERCP) in patients with a prior Billroth II gastrectomy. We retrospectively evaluated the safety and effectiveness of ampullary intervention using fully covered self-expandable metal stents (FCSEMSs) for the management of common bile duct (CBD) stones in a subset of patients with a history of Billroth II gastrectomy. METHODS: This retrospective analysis involved patients with a prior Billroth II gastrectomy who underwent ampullary intervention with FCSEMSs for the management of CBD stones...
August 7, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30122329/it-is-necessary-to-exam-bottom-and-top-slide-smears-of-eus-fna-for-pancreatic-cancer
#10
Jong-Chan Lee, Haeryoung Kim, Hyoung Woo Kim, Jongchan Lee, Kyu-Hyun Paik, Jingu Kang, Jin-Hyeok Hwang, Jaihwan Kim
BACKGROUND: Despite many reports on the diagnostic yield of cytology from endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), inter-slide differences are unknown. This prospective study aimed to compare diagnostic yield and cellular characteristics of bottom slides (BS) and top slides (TS) from EUS-FNA cytology performed without an on-site cytopathologist. METHODS: In patients with suspected pancreatic cancer on previous imaging explorations, a single endoscopist performed EUS-FNA and obtained 2 sets of cytology slide (8 BS and 8 TS), 1 cellblock slide, and 1 biopsy slide...
August 7, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30135046/novel-multimodal-analgesia-regimen-improves-post-tace-pain-in-patients-with-hepatocellular-carcinoma
#11
Jian-Guo Guo, Lu-Ping Zhao, Yue-Feng Rao, Yin-Ping Gao, Xue-Jiao Guo, Tan-Yang Zhou, Zhi-Ying Feng, Jun-Hui Sun, Xiao-Yang Lu
BACKGROUD: Transarterial chemoembolization (TACE) is the primary palliative treatment for patients with unresectable hepatocellular carcinoma (HCC). However, it is often accompanied by postoperative pain which hinder patient recovery. This study was to examine whether preemptive parecoxib and sufentanil-based patient controlled analgesia (PCA) could improve the pain management in patients receiving TACE for inoperable HCC. METHODS: From June to December 2016, 84 HCC patients undergoing TACE procedure were enrolled...
August 3, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30077607/prediction-of-neoantigens-and-their-application-in-cancer-treatment
#12
EDITORIAL
Bao Jin, Ying-Yi Wang, Shun-Da Du
No abstract text is available yet for this article.
July 27, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30115516/impact-of-body-composition-on-survival-and-morbidity-after-liver-resection-in-hepatocellular-carcinoma-patients
#13
Andreas Kroh, Diane Uschner, Toine Lodewick, Roman M Eickhoff, Wenzel Schöning, Florian T Ulmer, Ulf P Neumann, Marcel Binnebösel
BACKGROUND: Hepatocellular carcinoma is the most common innate liver tumor. Due to improved surgical techniques, even extended resections are feasible, and more patients can be treated with curative intent. As the liver is the central metabolic organ, preoperative metabolic assessment is crucial for risk stratification. Sarcopenia, obesity and sarcopenic obesity characterize body composition and metabolic status. Here we present the impact of body composition on survival after liver resection in patients with hepatocellular carcinoma...
July 26, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30082195/revision-of-bilateral-self-expandable-metallic-stents-placed-using-the-stent-in-stent-technique-for-malignant-hilar-biliary-obstruction
#14
Jun Hyuk Son, Hee Seung Lee, Sang Hyub Lee, Seungmin Bang, Jinwoo Kang, Woo Hyun Paik, Ji Kon Ryu, Yong-Tae Kim
BACKGROUND: Endoscopic biliary decompression using bilateral self-expandable metallic stent (SEMS) placed using the stent-in-stent (SIS) technique is considered favorable for unresectable malignant hilar biliary obstruction (MHBO). However, occlusion of the bilateral SIS placement is frequent and revision can be challenging. This study was performed to investigate the efficacy, the long-term patency and the appropriate approach for revision of occluded bilateral SIS placement in unresectable MHBO...
July 26, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30077606/post-operative-albumin-bilirubin-grade-predicts-long-term-outcomes-among-child-pugh-grade-a-patients-with-hepatocellular-carcinoma-after-curative-resection
#15
Masataka Amisaki, Ei Uchinaka, Masaki Morimoto, Naruo Tokuyasu, Teruhisa Sakamoto, Soichiro Honjo, Hiroaki Saito, Yoshiyuki Fujiwara
BACKGROUND: Although Child-Pugh grade A patients with hepatocellular carcinoma (HCC) are candidates for curative resection, some may have a poor prognosis. The albumin-bilirubin (ALBI) grade, a measure of liver function based on albumin and bilirubin, has the potential to detect Child-Pugh grade A HCC patients with poor prognosis. Because components of the ALBI grade can be measured easily even after surgery, we explored the predictive values of ALBI in patient prognosis after HCC resection...
July 26, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30054169/guidelines-for-the-diagnosis-and-treatment-of-pancreatic-adenocarcinoma-2018-edition-a-standardized-procedure-recommended-in-china
#16
EDITORIAL
Wen-Quan Wang, Liang Liu, Quan-Xing Ni, Xian-Jun Yu
No abstract text is available yet for this article.
July 24, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30082196/multidisciplinary-management-of-hepatobiliary-tumors-in-the-era-of-precision-medicine
#17
LETTER
Jian-Zhen Lin, Yi Bai, An-Qiang Wang, Jun-Yu Long, Wei-Yu Xu, Ke Hu, Lin Zhao, Jie Pan, Xin-Ting Sang, Hai-Tao Zhao
No abstract text is available yet for this article.
July 17, 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30173787/histopathological-findings-in-cholecystectomies-specimens-a-single-institution-study-of-20-584-cases
#18
Slim Charfi, Naourez Gouiaa, Hela Mnif, Lassaad Chtourou, Nabil Tahri, Bassem Abid, Rafik Mzali, Tahya Sellami Boudawara
BACKGROUND: The histopathological examination of cholecystectomy specimens has not been standardized with a debate concerning the routine and the selective approach. The aim of this study was to assess the information obtained from routine histopathological examination of cholecystectomy specimens. METHODS: All histopathological reports of cholecystectomy specimens between January 2003 and December 2016 were analyzed, including a clinical diagnosis of benign gallstone disease or cholecystitis...
August 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30173786/compromised-nutritional-status-in-patients-with-end-stage-liver-disease-role-of-gut-microbiota
#19
REVIEW
Maria Vasco, Rossella Paolillo, Concetta Schiano, Linda Sommese, Oreste Cuomo, Claudio Napoli
BACKGROUND: Patients with end-stage liver disease (ESLD) have a compromised nutritional status because of the liver crucial role in regulating metabolic homeostasis and energy balance. DATA SOURCES: A systematic review of literature based on extensive relevant articles published from 2001 to 2017 in English in PubMed database was performed by searching keywords such as liver disease, non-alcoholic liver disease, alcoholic liver disease, malnutrition, epigenetics, gut microbiota, and probiotics...
August 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/30108018/new-onset-hyperglycemia-immediately-after-liver-transplantation-a-national-survey-from-china-liver-transplant-registry
#20
Qing-Hong Ke, Hai-Tao Huang, Qi Ling, Ji-Min Liu, Si-Yi Dong, Xiang-Xiang He, Wen-Jin Zhang, Shu-Sen Zheng
BACKGROUND: New-onset hyperglycemia (NOH) is a common phenomenon after liver transplantation (LT), but its impact on clinical outcomes has not yet been fully assessed. We aimed to evaluate the etiology and prognosis of NOH within 1 month after LT. METHODS: The data of 3339 adult patients who underwent primary LT from donation after citizen death between January 2010 and June 2016 were extracted from China Liver Transplant Registry database and analyzed. NOH was defined as fasting blood glucose ≥7...
August 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
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