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Metabolic Syndrome and related Disorders

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https://www.readbyqxmd.com/read/27869531/associations-between-lifestyle-characteristics-and-the-presence-of-nonalcoholic-fatty-liver-disease-a-case-control-study
#1
Christina N Katsagoni, Michael Georgoulis, George V Papatheodoridis, Elisabeth Fragopoulou, Panagiota Ioannidou, Mariviki Papageorgiou, Alexandra Alexopoulou, Nikolaos Papadopoulos, Melanie Deutsch, Meropi D Kontogianni
BACKGROUND: Dietary and physical activity (PA) habits have been suggested as important factors for nonalcoholic fatty liver disease (NAFLD). Published data are mainly focused on the effect of either diet or exercise, whereas data on other aspects like sleep remain sparse. The aim of this study was to explore potential associations between dietary intake, PA, and sleeping habits, and the presence of NAFLD. METHODS: One hundred patients with ultrasound-proven NAFLD and 55 healthy controls matched for age, sex, and body mass index were included...
November 21, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27869528/the-association-between-measures-of-fitness-and-metabolic-health-in-treatment-seeking-youth-with-obesity
#2
Emily Hill Guseman, Samuel P Cauffman, Jared M Tucker, Lucie Smith, Joey C Eisenmann, William Stratbucker
BACKGROUND: Both cardiorespiratory fitness (CRF) and measures of muscular fitness are associated with metabolic syndrome in adults. However, limited information exists about these relationships in youth with severe obesity who are at increased risk of metabolic dysfunction. The purpose of this study was to examine the relationship between fitness and metabolic health in treatment-seeking youth with obesity. METHODS: Data for this analysis were collected at the time of baseline visits at a stage 3 pediatric weight management center...
November 21, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27869525/oxidative-priority-meal-frequency-and-the-energy-economy-of-food-and-activity-implications-for-longevity-obesity-and-cardiometabolic-disease
#3
Raymond J Cronise, David A Sinclair, Andrew A Bremer
In most modern societies, the relationship that many individuals have with food has fundamentally changed from previous generations. People have shifted away from viewing food as primarily sustenance, and rather now seek out foods based on pure palatability or specific nutrition. However, it is far from clear what optimal nutrition is for the general population or specific individuals. We previously described the Food Triangle as a way to organize food based on an increasing energy density paradigm, and now expand on this model to predict the impact of oxidative priority and both nutrient and fiber density in relation to caloric load...
November 21, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27824511/hyperuricemia-and-cardiovascular-disease-what-is-left-to-prove
#4
William E Winter
No abstract text is available yet for this article.
November 8, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27809669/polymorphisms-of-cytokine-genes-and-polycystic-ovary-syndrome-a-review
#5
Josiane Bazzo de Alencar, Hugo Vicentin Alves, Laise Nayana Sala Elpidio, Jeane Eliete Laguila Visentainer, Ana Maria Sell
BACKGROUND: Polycystic ovary syndrome (PCOS) is the endocrinopathy that affects women in their reproductive age. The physiopathology involves multifactorial mechanisms, including cytokine gene regulation. METHODS: The review was conducted in the database PubMed, with articles published between 2005 and 2015. The selected studies evaluated the single-nucleotide polymorphisms (SNPs) of cytokines genes in association with PCOS. Twenty-four studies met the inclusion criteria and showed the SNPs of cytokines that were associated or not with PCOS...
November 3, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27797643/modern-management-of-familial-hypercholesterolemia
#6
P Barton Duell, Ishwarlal Jialal
Familial hypercholesterolemia (FH) is a common genetic disorder that can manifest clinically as both the severe homozygous (HoFH) form that often presents in childhood and the commoner heterozygous (HeFH) form that is typically identified in adults. The majority of genetic causes are due to defects in low-density lipoprotein (LDL) receptor synthesis and action. Until recently, it was exceedingly difficult to achieve the goal of a 50% reduction in LDL-cholesterol or LDL-C < 70-100 in these patients. Established therapies include statins, niacin, bile-acid sequestrants, and ezetimibe in various combinations...
October 31, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27782779/effects-of-endurance-training-on-the-skeletal-muscle-nitric-oxide-metabolism-in-insulin-independent-type-2-diabetic-men-a-pilot-study
#7
Christian Brinkmann, Benedikt Schulte-Körne, Marijke Grau, Sinja Obels, Roman Kemmerling, Thorsten Schiffer, Wilhelm Bloch, Klara Brixius
BACKGROUND: Increases in the amount of inducible nitric oxide synthase (iNOS) protein and abnormal production of nitric oxide (NO) in skeletal muscle have been suggested to be associated with peripheral insulin resistance in patients with type 2 diabetes mellitus (T2DM). This pilot study analyzed whether a 3-month endurance training can affect iNOS protein and NO metabolite levels in the vastus lateralis muscle of insulin-independent T2DM men, thereby affecting the patients` glycemic control...
October 26, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27754772/determinants-of-improvement-in-left-ventricular-diastolic-function-following-a-1-year-lifestyle-modification-program-in-abdominally-obese-men-with-features-of-the-metabolic-syndrome
#8
Jacinthe Leclerc, Marie Arsenault, Jean-Pierre Després, Patrice Brassard, Valérie Gaudreault, Jean Bergeron, Natalie Alméras, Angelo Tremblay, Audrey Auclair, Marie-Kristelle Ross, Stéphanie Denault-Bissonnette, Paul Poirier
BACKGROUND: Abdominal obesity and presence of the metabolic syndrome (MetS) are associated with cardiac abnormalities. Among those, left ventricular diastolic dysfunction (LVDD) is the most frequently encountered in clinical practice. Few studies evaluated the reversibility of LVDD by an approach promoting lifestyle modifications in abdominally obese subjects with MetS. METHODS: We assessed the impact of a 1-year lifestyle modification program combining nutritional and physical activity counseling on LVDD and metabolic profile of abdominally obese men with MetS...
October 18, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27754771/metabolic-syndrome-development-during-aging-with-special-reference-to-obesity-without-the-metabolic-syndrome
#9
Vendela Roos, Sölve Elmståhl, Erik Ingelsson, Johan Sundström, Johan Ärnlöv, Lars Lind
BACKGROUND: Obesity and its associated metabolic complications continue to increase worldwide. We investigated the development of metabolic syndrome (MetS) during aging in relation to body mass index (BMI) and exercise habits. We assigned special emphasis to the metabolic stability in individuals with obesity, but without MetS, a condition often referred to as metabolically healthy obesity. MATERIALS AND METHODS: Cross-sectional analysis was carried out in a sample of 19,129 men and women aged 45-75 years from the EpiHealth study...
October 18, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27740886/association-between-the-duration-of-periodontitis-and-increased-cardiometabolic-risk-factors-a-9-year-cohort-study
#10
Toyoko Morita, Yoji Yamazaki, Chika Fujiharu, Takanori Ishii, Misae Seto, Norihide Nishinoue, Yoshiyuki Sasaki, Kumiko Nakai, Hideki Tanaka, Takayuki Kawato, Masao Maeno
BACKGROUND: Epidemiological studies have reported that periodontitis and cardiometabolic disease such as cardiovascular disease and type 2 diabetes are associated; however, there have been very few prospective cohort studies on this topic. Therefore, we conducted a 9-year follow-up study to examine the relationship between the duration of periodontitis and cardiometabolic risk factors, including hypertension, hyperglycemia, dyslipidemia, and obesity. METHODS: The study participants comprised 572 adult industrial workers (417 men and 155 women; mean age, 37...
October 14, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27740885/waist-to-height-ratio-compared-to-standard-obesity-measures-as-predictor-of-cardiometabolic-risk-factors-in-asian-indians-in-north-india
#11
Naval K Vikram, Ahmad Nawid Latifi, Anoop Misra, Kalpana Luthra, Surya Prakash Bhatt, Randeep Guleria, Ravindra M Pandey
OBJECTIVE: The aim of this study was to compare the discriminatory ability of body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) in identifying the presence of cardiometabolic risk factors in Asian Indians. METHODS: This cross-sectional study involved 509 subjects (278 males and 231 females) aged 20-60 years from New Delhi, India. Measurements included complete clinical examination, blood pressure, weight, height, WC, BMI, WHR and WHtR, fasting blood glucose, lipid profile, and fasting insulin levels...
October 14, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27710160/treatment-of-nonalcoholic-fatty-liver-disease-with-long-chain-n-3-polyunsaturated-fatty-acids-in-humans
#12
Nirvair S Kelley
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a major risk factor for type 2 diabetes, cardiovascular disease, and liver failure. Treatment with n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFAs) produced variable success in improving NAFLD. The purpose of this review is to determine if n-3 LCPUFA will decrease markers of NAFLD, compare the efficacies of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and identify factors that contribute to discrepancies in results...
October 6, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27710153/sex-difference-in-the-association-between-metabolic-syndrome-and-left-ventricular-diastolic-dysfunction
#13
Hack-Lyoung Kim, Myung-A Kim, Sohee Oh, Mina Kim, Seong Mi Park, Hyun Ju Yoon, Mi Seung Shin, Kyung-Soon Hong, Gil Ja Shin, Wan-Joo Shim
BACKGROUND: Sex-related differences in the influence of metabolic syndrome (MetS) on various cardiovascular diseases have been suggested. The aim of this study was to investigate the effect of sex on the association between MetS and left ventricular (LV) diastolic dysfunction in patients with suspected coronary artery disease (CAD). METHODS: Two hundred ten patients (105 men and age-matched 105 women; mean age: 56.5 ± 10.9 years) undergoing elective coronary angiography for the evaluation of CAD were studied...
October 6, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27689409/increased-metabolic-disorders-and-impaired-insulin-secretory-function-in-the-first-degree-relatives-of-type-2-diabetic-patients-with-normal-glucose-tolerance
#14
Liling Deng, Songfang Liu, Yuan Gong, Haoming Tian, Yuanyuan Liu, Jie Song, Xingwu Ran, Honglin Yu, Xiangxun Zhang, Yang Long, Yan Ren
OBJECTIVE: To compare the metabolic status and pancreatic β-cell function in first-degree relatives (FDRs) of type 2 diabetic patients with normal glucose tolerance (NGT). MATERIALS AND METHODS: Three hundred twelve subjects, who were NGT-FDR of type 2 diabetic patients and 1348 subjects, who were NGT individuals with no family history of diabetes, were defined as NGT-FDRs and NGT-controls (NGT-C), respectively. Blood pressure, body weight, waist circumference, plasma glucose, lipid profile, and insulin levels were measured in all subjects...
September 30, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27676127/relationship-between-two-common-lipoprotein-lipase-variants-and-the-metabolic-syndrome-and-its-individual-components
#15
Julie K K Vishram, Tine W Hansen, Christian Torp-Pedersen, Sten Madsbad, Torben Jørgensen, Mogens Fenger, Stig Lyngbæk, Jørgen Jeppesen
BACKGROUND: Common lipoprotein lipase (LPL) variants are important determinants of triglycerides (TG) and high-density lipoprotein (HDL) cholesterol (C) concentrations. High TG/low HDL-C tend to cluster with hypertension, glucose intolerance, and abdominal obesity and comprise the metabolic syndrome (MetS). The role of LPL variants as a cause of MetS is unclear. This study investigated the relationship between two common LPL variants and the presence of MetS and its individual components...
September 27, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27399601/the-burden-of-obesity-elevated-blood-pressure-and-diabetes-in-uninsured-and-underinsured-adolescents
#16
Amanda E Staiano, Madeline Morrell, Daniel S Hsia, Gang Hu, Peter T Katzmarzyk
BACKGROUND: Obesity, elevated blood pressure (BP), and diabetes mellitus are rising among the general U.S. adolescent population, but prevalence estimates are not available for uninsured or Medicaid populations. METHODS: This retrospective epidemiological study extracted 155,139 electronic medical records collected between 1998 and 2012 on patients aged 10-19 years, from a clinical population predominantly uninsured or insured by Medicaid. Age, sex, race, height, weight, BP, and insurance type were captured at first clinic visit...
November 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27552667/glucagon-like-peptide-1-receptor-agonists-and-diabetic-cardiovascular-disease-implications-of-the-leader-study
#17
Arthur L M Swislocki, Ishwarlal Jialal
No abstract text is available yet for this article.
October 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27551743/subclinical-hypothyroidism-and-metabolic-syndrome-a-common-association-by-chance-or-a-cardiovascular-risk-driver
#18
Benedetta Maria Bonora, Gian Paolo Fadini
The metabolic syndrome (MS) and subclinical hypothyroidism (SCH) are highly prevalent in the general population. Cross-sectional epidemiological data suggest that a mutual association exists between the two, although the cause-effect relationship remains poorly elucidated. As SCH raises cholesterol, blood pressure, and visceral fat, it is easy to understand why it associates with MS. Rather, the reasons whereby MS patients are at higher risk for SCH are less apparent. Some studies have reported that SCH is itself characterized by high cardiovascular risk...
October 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27529580/relationship-between-metabolic-syndrome-and-cognitive-abilities-in-u-s-adolescents
#19
Muni Rubens, Venkataraghavan Ramamoorthy, Anshul Saxena, Florence George, Nancy Shehadeh, Jennifer Attonito, H Virginia McCoy, Consuelo M Beck-Sagué
BACKGROUND: Metabolic syndrome is increasingly common in U.S. adolescents and has been linked to cognitive dysfunction. Purpose of this study is to explore associations between metabolic syndrome and cognitive impairment in U.S. adolescents using population-based data. STUDY DESIGN: Participants included adolescents aged 12-16 years who participated in the National Health and Nutrition Examination Survey (NHANES) III. The main outcome measures included assessments of cognitive function using Wide Range Achievement Test-Revised (WRAT-R) and Wechsler Intelligence Scale for Children-Revised (WISC-R) tools...
October 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27513679/associations-of-circulating-pyy3-36-concentrations-with-metabolic-syndrome-in-extremely-obese-subjects
#20
Sasa Dusanov, Kari Brandal, Eli Heggen, Serena Tonstad
BACKGROUND: The gut hormone peptide YY3-36 (PYY3-36) plays major roles in regulation of appetite and energy metabolism, mediates beneficial effects of bariatric surgery, and may be a potential weight-reducing and glucose-modulating therapy. Obesity may influence the metabolic expression of circulating PYY3-36 and metabolic markers. We studied the relationship of PYY3-36 concentrations with metabolic syndrome (MetSyn) components, lipids, insulin resistance, and inflammatory biomarkers in subjects with extreme obesity...
October 2016: Metabolic Syndrome and related Disorders
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