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Metabolic Syndrome and related Disorders

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https://www.readbyqxmd.com/read/28080219/adipose-tissue-insulin-resistance-in-gestational-diabetes
#1
Batbayar Tumurbaatar, Aaron T Poole, Gayle Olson, Michel Makhlouf, Hanaa S Sallam, Shwetha Thukuntla, Sucharitha Kankanala, Obos Ekhaese, Guillermo Gomez, Manisha Chandalia, Nicola Abate
BACKGROUND: Gestational diabetes mellitus (GDM) is a metabolic disorder characterized by insulin resistance (IR) and altered glucose-lipid metabolism. We propose that ectonucleotide pyrophosphate phosphodiesterase-1 (ENPP1), a protein known to induce adipocyte IR, is a determinant of GDM. Our objective was to study ENPP1 expression in adipose tissue (AT) of obese pregnant women with or without GDM, as well as glucose tolerance in pregnant transgenic (Tg) mice with AT-specific overexpression of human ENPP1...
January 12, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28075222/expression-of-myd88-in-adipose-tissue-of-obese-people-is-there-some-role-in-the-development-of-metabolic-syndrome
#2
Ada M Cuevas, Mariana Lazo, Isabel Zuñiga, Fernando Carrasco, Jim J Potter, Veronica Alvarez, Marcos Berry, Fernando Maluenda, Mario Ferrario, Jeanne M Clark
BACKGROUND: The mechanism leading to the development of metabolic complications in obese individuals is not fully understood. Thus, the objective of this study was to examine differences in insulin resistance, inflammation, cytokine and adipokine levels, and expression of selected genes across obese individuals with different number of metabolic syndrome (MetS) components. METHODS: Forty obese individuals who underwent bariatric surgery, divided in three groups based on the number of components of MetS, in addition to abdominal obesity (0, 1, and 2-3 additional components), were studied...
January 11, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28056187/temporal-effect-of-bariatric-surgery-on-predicted-10-year-and-lifetime-cardiovascular-risk-at-1-month-6-months-and-5-years-following-surgery-a-pilot-study
#3
Thinzar Min, Sarah L Prior, Scott Caplin, Jonathan D Barry, Jeffrey W Stephens
BACKGROUND AND AIMS: Cardiovascular (CV) risk equations are routinely used to predict risk in nonbariatric populations, but have not been studied in depth in patients undergoing bariatric surgery and specifically those with impaired glucose regulation. The aim of this pilot study was to investigate changes in the 10-year and lifetime predicted CV risk in subjects with impaired glucose regulation before, 1 month, 6 months, and 5 years after bariatric surgery. METHOD AND RESULTS: A nonrandomized prospective study was conducted of 45 participants with impaired glucose regulation undergoing temporal assessments during follow-up...
January 5, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28051354/effect-of-almond-supplementation-on-glycemia-and-cardiovascular-risk-factors-in-asian-indians-in-north-india-with-type-2-diabetes-mellitus-a-24-week-study
#4
Seema Gulati, Anoop Misra, Ravindra M Pandey
BACKGROUND: Type 2 diabetes (T2D) statistics have reached menacing proportions in India. Appropriate dietary intervention, as part of healthy lifestyle, is imperative to curb further spread of this disease. OBJECTIVES: This pre-post intervention study was conducted in New Delhi, India, to investigate the effects of daily consumption of almonds for 24 weeks in T2D subjects, specifically on measures of glycemia and cardiovascular disease (CVD) risk factors. METHODS AND STUDY DESIGN: In this study, the 24-week intervention period was preceded by a control diet and exercise run-in period of 3 weeks...
January 4, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28045599/if-the-metabolic-winter-is-coming-when-will-it-be-summer
#5
Thomas Wood
No abstract text is available yet for this article.
January 3, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28026999/the-association-of-sleep-duration-and-morbid-obesity-in-a-working-population-the-baptist-health-south-florida-employee-study
#6
Muhammad Aziz, Chukwuemeka U Osondu, Adnan Younus, Rehan Malik, Maribeth Rouseff, Sankalp Das, Henry Guzman, Wasim Maziak, Salim Virani, Theodore Feldman, Arthur S Agatston, Emir Veledar, Ehimen C Aneni, Khurram Nasir
BACKGROUND: The current study aimed to determine the relationship between self-reported sleep duration and morbid obesity in an employee population. METHODS: Baptist Health South Florida conducts an annual Health Risk Assessment (HRA) for its employees. Data for this cross-sectional study was collected via this HRA in 2014, and included information on self-reported sleep duration, height and weight for body mass index (BMI), and other biometric measures. Average sleep duration was categorized as short sleep (<6 hr), optimal sleep (6-7...
December 27, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27997282/effectiveness-of-a-community-based-physical-activity-and-nutrition-behavior-intervention-on-features-of-the-metabolic-syndrome-a-cluster-randomized-controlled-trial
#7
Van Dinh Tran, Anthony P James, Andy H Lee, Jonine Jancey, Peter A Howat, Le Thi Phuong Mai
BACKGROUND: Metabolic syndrome (MetS) and its subclinical diseases are now public health problems in Vietnam. This study aimed at determining the effectiveness of a physical activity and nutrition program for reducing MetS proportion and its components among adults with MetS in Hanam province, Vietnam. METHODS: A total of 417 volunteers aged 50-65 years with MetS were recruited from 10 communes. The communes were randomly allocated to an intervention group (five communes, n = 214) and a control group (five communes, n = 203)...
December 20, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27937806/association-between-hyperuricemia-and-major-adverse-cardiac-events-in-patients-with-acute-myocardial-infarction
#8
Naresh Ranjith, Nomcebo N Myeni, Ben Sartorius, Chamsanqua Mayise
BACKGROUND: To investigate the association between hyperuricemia and major adverse cardiac events (MACE) in patients with acute myocardial infarction (AMI). METHODS: Consecutive patients admitted with AMI to the Coronary Care Unit at R. K. Khan Hospital (Durban, South Africa) between the years 2006 and 2014 were included. Demographic data, including clinical and biochemical information stored in an electronic database, were obtained from all patients. RESULTS: A total of 2683 patients were studied, of whom 65% were males...
December 12, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27929741/cerebral-microvascular-dysfunction-and-inflammation-are-improved-by-centrally-acting-antihypertensive-drugs-in-metabolic-syndrome
#9
Vanessa Estato, Alessandro Nascimento, Barbara Antunes, Fabiana Gomes, Laura Coelho, Raquel Rangel, Luciana Garzoni, Anissa Daliry, Pascal Bousquet, Eduardo Tibiriçá
BACKGROUND: We aimed to investigate the effects of chronic oral treatment with centrally acting antihypertensive drugs, such as clonidine (CLO), an α2-adrenoceptor agonist, or LNP599, a selective I1 imidazoline receptor agonist, on brain microvascular function in rats with high-fat diet (HFD)-induced metabolic syndrome. METHODS: Male Wistar Kyoto rats were maintained on a normal diet (CON) or a HFD for 20 weeks. After this period, the HFD group received oral CLO (0...
December 8, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27929732/the-prevalence-of-thyroid-nodules-and-their-association-with-metabolic-syndrome-risk-factors-in-a-moderate-iodine-intake-area
#10
Shangyong Feng, Zhenwen Zhang, Shuhang Xu, Xiaodong Mao, Yu Feng, Yan Zhu, Chao Liu
BACKGROUND: To investigate the prevalence of thyroid nodules (TNs) and to evaluate the association between TNs and metabolic syndrome (MetS) in the moderate iodine intake area of Jiangsu, China. SUBJECTS AND METHODS: A cross-sectional study was carried out in a Chinese community-based epidemiological investigation from January to December 2014. A questionnaire was completed by 6494 subjects (2427 men and 4067 women). Thyroid ultrasound was performed by using a 7...
December 8, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27925858/physical-activity-contributes-to-several-sleep-cardiometabolic-health-relationships
#11
Thirumagal Kanagasabai, Michael C Riddell, Chris I Ardern
PURPOSE: To estimate the contribution of accelerometer-derived physical activity to the relationship between sleep and cardiometabolic health. METHODS: Data from the 2005 to 2006 US National Health and Nutritional Examination Survey were used (N = 1226; 20 years+). Metabolic syndrome (MetS) was defined by the Joint Interim Statement, and sleep quality and quantity by the Sleep Disorders Questionnaire. Physical activity intensities were defined by activity thresholds (counts per minute) as sedentary activity (0-99), light intensity (100-759), lifestyle activity (760-2019), moderate intensity (2020-5996), and vigorous intensity (≥5999)...
December 7, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27869531/associations-between-lifestyle-characteristics-and-the-presence-of-nonalcoholic-fatty-liver-disease-a-case-control-study
#12
Christina N Katsagoni, Michael Georgoulis, George V Papatheodoridis, Elisabeth Fragopoulou, Panagiota Ioannidou, Mariviki Papageorgiou, Alexandra Alexopoulou, Nikolaos Papadopoulos, Melanie Deutsch, Meropi D Kontogianni
BACKGROUND: Dietary and physical activity (PA) habits have been suggested as important factors for nonalcoholic fatty liver disease (NAFLD). Published data are mainly focused on the effect of either diet or exercise, whereas data on other aspects like sleep remain sparse. The aim of this study was to explore potential associations between dietary intake, PA, and sleeping habits, and the presence of NAFLD. METHODS: One hundred patients with ultrasound-proven NAFLD and 55 healthy controls matched for age, sex, and body mass index were included...
November 21, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27869528/the-association-between-measures-of-fitness-and-metabolic-health-in-treatment-seeking-youth-with-obesity
#13
Emily Hill Guseman, Samuel P Cauffman, Jared M Tucker, Lucie Smith, Joey C Eisenmann, William Stratbucker
BACKGROUND: Both cardiorespiratory fitness (CRF) and measures of muscular fitness are associated with metabolic syndrome in adults. However, limited information exists about these relationships in youth with severe obesity who are at increased risk of metabolic dysfunction. The purpose of this study was to examine the relationship between fitness and metabolic health in treatment-seeking youth with obesity. METHODS: Data for this analysis were collected at the time of baseline visits at a stage 3 pediatric weight management center...
November 21, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27869525/oxidative-priority-meal-frequency-and-the-energy-economy-of-food-and-activity-implications-for-longevity-obesity-and-cardiometabolic-disease
#14
Raymond J Cronise, David A Sinclair, Andrew A Bremer
In most modern societies, the relationship that many individuals have with food has fundamentally changed from previous generations. People have shifted away from viewing food as primarily sustenance, and rather now seek out foods based on pure palatability or specific nutrition. However, it is far from clear what optimal nutrition is for the general population or specific individuals. We previously described the Food Triangle as a way to organize food based on an increasing energy density paradigm, and now expand on this model to predict the impact of oxidative priority and both nutrient and fiber density in relation to caloric load...
November 21, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27824511/hyperuricemia-and-cardiovascular-disease-what-is-left-to-prove
#15
William E Winter
No abstract text is available yet for this article.
November 8, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27782779/effects-of-endurance-training-on-the-skeletal-muscle-nitric-oxide-metabolism-in-insulin-independent-type-2-diabetic-men-a-pilot-study
#16
Christian Brinkmann, Benedikt Schulte-Körne, Marijke Grau, Sinja Obels, Roman Kemmerling, Thorsten Schiffer, Wilhelm Bloch, Klara Brixius
BACKGROUND: Increases in the amount of inducible nitric oxide synthase (iNOS) protein and abnormal production of nitric oxide (NO) in skeletal muscle have been suggested to be associated with peripheral insulin resistance in patients with type 2 diabetes mellitus (T2DM). This pilot study analyzed whether a 3-month endurance training can affect iNOS protein and NO metabolite levels in the vastus lateralis muscle of insulin-independent T2DM men, thereby affecting the patients` glycemic control...
October 26, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27809669/polymorphisms-of-cytokine-genes-and-polycystic-ovary-syndrome-a-review
#17
Josiane Bazzo de Alencar, Hugo Vicentin Alves, Laise Nayana Sala Elpidio, Jeane Eliete Laguila Visentainer, Ana Maria Sell
BACKGROUND: Polycystic ovary syndrome (PCOS) is the endocrinopathy that affects women in their reproductive age. The physiopathology involves multifactorial mechanisms, including cytokine gene regulation. METHODS: The review was conducted in the database PubMed, with articles published between 2005 and 2015. The selected studies evaluated the single-nucleotide polymorphisms (SNPs) of cytokines genes in association with PCOS. Twenty-four studies met the inclusion criteria and showed the SNPs of cytokines that were associated or not with PCOS...
December 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27797643/modern-management-of-familial-hypercholesterolemia
#18
P Barton Duell, Ishwarlal Jialal
Familial hypercholesterolemia (FH) is a common genetic disorder that can manifest clinically as both the severe homozygous (HoFH) form that often presents in childhood and the commoner heterozygous (HeFH) form that is typically identified in adults. The majority of genetic causes are due to defects in low-density lipoprotein (LDL) receptor synthesis and action. Until recently, it was exceedingly difficult to achieve the goal of a 50% reduction in LDL-cholesterol or LDL-C < 70-100 in these patients. Established therapies include statins, niacin, bile-acid sequestrants, and ezetimibe in various combinations...
December 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27754772/determinants-of-improvement-in-left-ventricular-diastolic-function-following-a-1-year-lifestyle-modification-program-in-abdominally-obese-men-with-features-of-the-metabolic-syndrome
#19
Jacinthe Leclerc, Marie Arsenault, Jean-Pierre Després, Patrice Brassard, Valérie Gaudreault, Jean Bergeron, Natalie Alméras, Angelo Tremblay, Audrey Auclair, Marie-Kristelle Ross, Stéphanie Denault-Bissonnette, Paul Poirier
BACKGROUND: Abdominal obesity and presence of the metabolic syndrome (MetS) are associated with cardiac abnormalities. Among those, left ventricular diastolic dysfunction (LVDD) is the most frequently encountered in clinical practice. Few studies evaluated the reversibility of LVDD by an approach promoting lifestyle modifications in abdominally obese subjects with MetS. METHODS: We assessed the impact of a 1-year lifestyle modification program combining nutritional and physical activity counseling on LVDD and metabolic profile of abdominally obese men with MetS...
December 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27740886/association-between-the-duration-of-periodontitis-and-increased-cardiometabolic-risk-factors-a-9-year-cohort-study
#20
Toyoko Morita, Yoji Yamazaki, Chika Fujiharu, Takanori Ishii, Misae Seto, Norihide Nishinoue, Yoshiyuki Sasaki, Kumiko Nakai, Hideki Tanaka, Takayuki Kawato, Masao Maeno
BACKGROUND: Epidemiological studies have reported that periodontitis and cardiometabolic disease such as cardiovascular disease and type 2 diabetes are associated; however, there have been very few prospective cohort studies on this topic. Therefore, we conducted a 9-year follow-up study to examine the relationship between the duration of periodontitis and cardiometabolic risk factors, including hypertension, hyperglycemia, dyslipidemia, and obesity. METHODS: The study participants comprised 572 adult industrial workers (417 men and 155 women; mean age, 37...
December 2016: Metabolic Syndrome and related Disorders
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