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Applied Health Economics and Health Policy

Megan Dale, Helen Morgan, Kimberly Carter, Judith White, Grace Carolan-Rees
The Peristeen transanal irrigation system is intended to allow people with bowel dysfunction to flush out the lower part of the bowel as part of their bowel management strategy. Peristeen was the subject of an evaluation by the National Institute for Health and Care Excellence, through its Medical Technologies Evaluation Programme, for the management of bowel dysfunction. The company, Coloplast, submitted a case for adoption of the technology, claiming that the technology improves the severity of chronic constipation or faecal incontinence and improves quality of life for people with bowel dysfunction...
November 14, 2018: Applied Health Economics and Health Policy
Chunjuan Qiu, Xianyi Wu
BACKGROUND: As the largest developing country in the world, China is still on its way towards building an adequate system of health insurance through continuous reforms. For the elderly in China, an effective medical security system might be especially helpful. OBJECTIVE: This study investigates the effect of medical insurance on outpatient visits by elderly Chinese in order to identify effective policies to improve the Chinese medical security system. METHODS: Based on data taken from the China Health and Retirement Longitudinal Study, eleven candidate models were analyzed, among which a finite mixture negative binomial model with two components was chosen as the theoretical foundation for an analysis of the effect of medical insurance on outpatient visits by elderly Chinese...
November 9, 2018: Applied Health Economics and Health Policy
Carlos Vílchez-Román, Sol Sanguinetti, Edward Mezones-Holguín
No abstract text is available yet for this article.
October 29, 2018: Applied Health Economics and Health Policy
Dominik J Wettstein, Stefan Boes
OBJECTIVES: The aim of this review is to assess the current state of empirical research regarding the effectiveness of national pricing regulations of the patent-protected market for prescription pharmaceuticals. Effectiveness is understood to be the capacity of policies to have a desired impact on outcomes, such as health status, patient access, healthcare expenditure, and research investments, among others. METHODS: A systematic review of the published literature on pricing regulations in OECD countries was performed...
October 27, 2018: Applied Health Economics and Health Policy
Francisca Crispi, Huseyin Naci, Eva Barkauskaite, Leeza Osipenko, Elias Mossialos
BACKGROUND: The Medical Technologies Evaluation Programme (MTEP) of NICE in England aims to evaluate medical devices that are deemed to be cost-saving or cost-neutral and produce Medical Technology Guidance (MTG) to encourage their adoption. OBJECTIVE: To review the MTGs since MTEP's inception in 2009 until February 2017. METHODS: One researcher assessed all published MTGs and extracted data on the clinical and economic evidence supporting each technology...
October 26, 2018: Applied Health Economics and Health Policy
Anna Kemp-Casey, Nicole Pratt, Emmae Ramsay, Elizabeth E Roughead
OBJECTIVES: To describe how post-market utilisation analysis in Australia informs cost-effectiveness assessment and pricing decisions, using aflibercept and ranibizumab as case studies. METHODS: Pharmaceutical claims were used to identify initiators of aflibercept and ranibizumab in the year after aflibercept-listing (December 2012), and ranibizumab initiators in the year before aflibercept listing. The dispensing rates for each cohort were calculated, and their demographic and clinical characteristics compared using Kruskal-Wallis tests...
October 25, 2018: Applied Health Economics and Health Policy
Tara A Lavelle, Brittany N D'Cruz, Babak Mohit, Wendy J Ungar, Lisa A Prosser, Kate Tsiplova, Montserrat Vera-Llonch, Pei-Jung Lin
BACKGROUND: Childhood illness can impose significant costs and health strains on family members, but these are not routinely captured by pediatric economic evaluations. This review investigated how family "spillover effects" related to costs and health outcomes are considered in pediatric cost-utility analyses (CUAs). METHODS: We reviewed pediatric CUAs published between 2000 and 2015 using the Tufts Medical Center Cost-effectiveness Analysis (CEA) Registry and the Pediatric Economic Database Evaluation (PEDE) Registry...
October 22, 2018: Applied Health Economics and Health Policy
Jordana K Schmier, Jasmine D Patel, Megan J Leonhard, Prem A Midha
BACKGROUND: Advanced heart failure (HF) can be treated conservatively or aggressively, with left ventricular assist devices (LVADs) and heart transplant (HT) being the most aggressive strategies. OBJECTIVE: The goal of this review was to identify, describe, critique and summarize published cost-effectiveness analyses on LVADs for adults with HF. METHODS: We conducted a literature search using PubMed and ProQuest DIALOG databases to identify English-language publications from 2006 to 2017 describing cost-effectiveness analyses of LVADs and reviewed them against inclusion criteria...
October 22, 2018: Applied Health Economics and Health Policy
Georgia Kourlaba, Georgios Hillas, Theodoros Vassilakopoulos, Nikos Maniadakis
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a leading cause of disability and death worldwide, imposing a substantial socioeconomic burden on societies and patients due to the long-term management required. OBJECTIVE: To assess the economic burden of COPD in Greece and its potential determinants. METHODS: A population-based, random-digit dialled, telephone nationwide survey was conducted to recruit patients with COPD in Greece (N = 351)...
October 17, 2018: Applied Health Economics and Health Policy
Simon Eckermann, Lyn Phillipson, Richard Fleming
No abstract text is available yet for this article.
October 16, 2018: Applied Health Economics and Health Policy
Stella Nalukwago Settumba, Marian Shanahan, Willings Botha, Muhammad Zulilhaam Ramli, Georgina Mary Chambers
BACKGROUND: The contingent valuation (CV) method is an alternative approach to typical health economic methods for valuing interventions that have both health and non-health outcomes. Fertility treatment, such as in vitro fertilisation (IVF), fall into this category because of the significant non-health outcomes associated with having children. AIM: To estimate the general population's willingness to pay (WTP) for one cycle of IVF and one year of IVF treatment, and to test the reliability and validity of a CV instrument...
October 13, 2018: Applied Health Economics and Health Policy
Irene Eriksson, Mia von Euler, Rickard E Malmström, Brian Godman, Björn Wettermark
BACKGROUND: Early awareness and alert systems have been established in many countries but evidence on their ability to accurately prioritize new medicines (for early assessment) is limited. OBJECTIVE: The purpose of this study was to assess whether the Swedish Early Awareness and Alert System identified and prioritized (i.e., produced early assessment reports for) new medicines that would go on to have substantial economic impact. METHODS: We adapted a study design commonly used in the assessment of diagnostic test accuracy...
October 4, 2018: Applied Health Economics and Health Policy
Fang Xu, Yong Liu, Anne G Wheaton, Kristina M Rabarison, Janet B Croft
BACKGROUND: Few studies have addressed recent trends in hospitalization costs for inflammatory bowel disease (IBD). OBJECTIVE: We explored trends and described patient and hospital factors associated with hospitalization costs for IBD. METHODS: Using data from the 2003-2014 National Inpatient Sample for adults aged ≥ 18 years, we estimated costs using multivariable linear models and assessed linear trends by time periods using piecewise linear regressions...
September 27, 2018: Applied Health Economics and Health Policy
Neily Zakiyah, A D I van Asselt, D Setiawan, Q Cao, F Roijmans, M J Postma
OBJECTIVES: The aim was to estimate the long-term cost-effectiveness of improved family planning interventions to reduce the unmet need in low- and middle-income countries, with Indonesia and Uganda as reference cases. METHODS: The analysis was performed using a Markov decision analytic model, where current situation and several scenarios to reduce the unmet need were incorporated as the comparative strategies. Country-specific evidence was synthesized from the demographic and health survey and published studies...
September 4, 2018: Applied Health Economics and Health Policy
Judith J Gout-Zwart, Erien H J Olde Hengel, Petra Hoogland, Maarten J Postma
OBJECTIVES: Medication errors that lead to adverse drug reactions are a key cause of unintentional patient harm and subsequent economic burden. To prevent this, measurement of renal function could be considered. The aim of this study was to determine the budget impact of obtaining and evaluating renal function in community pharmacies in the Netherlands to prevent antibiotic-related hospitalizations. METHODS: A decision model was built to simulate the process of antibiotic prescriptions in community pharmacies with and without the use of a point-of-care test (PoCT) in patients aged 65 years and older...
September 3, 2018: Applied Health Economics and Health Policy
Etienne Nédellec, Judith Pineau, Patrice Prognon, Nicolas Martelli
OBJECTIVES: The objective of the present work was to assess the level of evidence in economic evaluations of percutaneous left atrial appendage closure devices, and to test the complementarity of three different tools for assessing the quality of economic evaluations. METHODS: We conducted a systematic review of articles in English or French listed in MEDLINE, Embase, Cochrane, the Cost-Effectiveness Analysis registry and the National Health Service Economic Evaluation Database...
August 31, 2018: Applied Health Economics and Health Policy
Scott A McDonald, Amirah Azzeri, Fatiha Hana Shabaruddin, Maznah Dahlui, Soek S Tan, Adeeba Kamarulzaman, Rosmawati Mohamed
INTRODUCTION: The World Health Organisation (WHO) has set ambitious goals to reduce the global disease burden associated with, and eventually eliminate, viral hepatitis. OBJECTIVE: To assist with achieving these goals and to inform the development of a national strategic plan for Malaysia, we estimated the long-term burden incurred by the care and management of patients with chronic hepatitis C virus (HCV) infection. We compared cumulative healthcare costs and disease burden under different treatment cascade scenarios...
August 25, 2018: Applied Health Economics and Health Policy
Trine Tornøe Platz, Nikolaj Siersbæk, Lars Peter Østerdal
The number of living donations of human organs, tissues, and cells falls far short of the need. Market-like arrangements to increase donation rates have been proposed, but they are broadly considered unacceptable due to ethical concerns and are therefore not policy relevant in most countries. The purpose of this paper is to explore a different approach to increasing living donations, namely through the use of ethically acceptable compensation of donors. We review the compensation practices in Europe and find a lack of reimbursement of incurred costs and lack of compensation for non-monetary losses, which create disincentives for donation...
August 25, 2018: Applied Health Economics and Health Policy
Cagdas Agirdas, Jordan G Holding
BACKGROUND: The Affordable Care Act (ACA) requires non-grandfathered private insurance plans, starting with plan years on or after September 23rd, 2010, to provide certain preventive care services without any cost sharing in the form of deductibles, copayments or co-insurance. This requirement may affect racial and ethnic disparities in preventive care as it provides the largest copay reduction in preventive care. OBJECTIVES: We ask whether the ACA's free preventive care benefits are associated with a reduction in racial and ethnic disparities in the utilization of four preventive services: cholesterol screenings, colonoscopies, mammograms, and Pap smears...
August 24, 2018: Applied Health Economics and Health Policy
Prithviraj Lakkakula
No abstract text is available yet for this article.
August 24, 2018: Applied Health Economics and Health Policy
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