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Nigerian Journal of Clinical Practice

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https://www.readbyqxmd.com/read/29192644/automated-centrifugal-therapeutic-plasma-exchange-option-for-guillain-barre-syndrome-a-report-from-calabar-nigeria
#1
O E Iheanacho, C Chimeziem, B S Sachais, P A Shi
Therapeutic plasma exchange (TPE) is performed frequently and effectively in developed countries, whereas the reverse is the case in developing countries. Guillain-Barre syndrome (GBS), synonymous with acute inflammatory demyelinating polyneuropathy, is an important indication for TPE, but this is rarely administered in the treatment of such patients in Nigeria due to lack of such automated facility, limited expertise, and high cost. This report therefore presents an uncommon case of GBS in which automated TPE was utilized in the management, with the aims of highlighting the current status and challenges of therapeutic apheresis services in Nigeria...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192643/multiple-primary-tumors
#2
M A Adeyanju, A A Ilori
Multiple primary tumors occur in clinical practice causing diagnostic dilemma. It is not very common, but the incidence has increased gradually since it was first described very many years ago. However, in spite of its increasing incidence, the presence of such primary malignancies in the breast and colon has been rare and far between, as against its presence in breast and lungs, both breasts, colon and stomach, two colonic sites, and endometrium and ovaries. It could be due to genetic disorders such as Li-Fraumeni syndrome in which case the affected individuals develop multiple cancers in childhood or early adulthood...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192642/importance-of-optical-diagnosis-in-early-gastric-cancer-a-case-report-of-early-gastric-signet-ring-cell-carcinoma
#3
P S Akabah, S Mocan, C Molnar, D Dobru
Gastric signet ring cell carcinoma (SRCC) is a rare form of highly malignant adenocarcinoma. It is an epithelial malignancy characterized by the histologic appearance of more than 50% of cells as signet ring cells filled with mucin. The incidence of SRCC is rising,[1],[2] therefore, the diagnosis of these cancers in the early stage is important as it is the only stage that curative measures can be done. A 49-year-old female was hospitalized due to epigastric pain, postprandial bloating for 3 months. Upper gastrointestinal endoscopy with narrow band imaging (NBI) showed 1...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192641/diabetes-or-hypertension-as-risk-indicators-for-missing-teeth-experience-an-exploratory-study-in-a-sample-of-mexican-adults
#4
V J Delgado-Pérez, R De La Rosa-Santillana, M L Márquez-Corona, L Ávila-Burgos, H Islas-Granillo, M Minaya-Sánchez, C E Medina-Solís, G Medina-SolIs
BACKGROUND: To determine an exploratory estimation of the strength of type 2 diabetes mellitus (T2DM) and hypertension diagnoses as risk indicators for missing teeth in a sample of Mexican adults. MATERIALS AND METHODS: A comparative cross-sectional study of sixty adult patients in a health center in Mexico included as dependent variable, the number of missing teeth (and having a functional dentition) and as independent variables, diagnoses for diabetes or hypertension, age, sex, maximum level of schooling, and tobacco use...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192640/axial-length-corneal-radius-of-curvature-ratio-and-refractive-status-in-an-adult-nigerian-population
#5
S A Badmus, A I Ajaiyeoba, B O Adegbehingbe, O H Onakpoya, A O Adeoye
AIM/BACKGROUND: Associations between axial length (AL) to corneal radius of curvature (CR) ratio and refractive status in a healthy Nigerian adult population were studied. MATERIALS AND METHODS: Healthy students and members of staff of Obafemi Awolowo Teaching Hospitals Complex, Ile-Ife, South West Nigeria, free of obvious ocular diseases except possible refractive errors were recruited. Consecutive consenting volunteers were recruited by simple random sampling and a proportionate sample of each population based on its representative fraction in the hospital community was recruited...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192639/intrathecal-ropivacaine-in-cesarean-delivery
#6
R Y Ateser, N Kayacan
OBJECTIVE: The aim of the present study was to evaluate the optimum dose of ropivacaine by comparing three different dosing regimens of isobaric ropivacaine 1% (naropin 10 mg/ml, Astra Zeneca) administered intrathecally and to demonstrate the effects of anesthesia in pregnant women scheduled for cesarean section. PATIENTS AND METHODS: Sixty ASA grade I-II patients were scheduled to undergo elective cesarean sections under spinal anesthesia. The patients were randomly assigned into three groups...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192638/clinical-outcomes-after-open-locked-intramedullary-nailing-of-closed-femoral-shaft-fractures-for-adult-patients-in-a-nigerian-hospital
#7
O N Salawu, G H Ibraheem, O M Babalola, D M Kadir, B A Ahmed, S B Agaja, A Olawepo, A A Nasir
BACKGROUND: Femoral shaft fractures are common injuries in adults. Closed locked intramedullary nailing is the recommended treatment for femoral shaft fractures due to its high union rate. OBJECTIVE: The objective of this study is to determine the outcome of management of closed femoral shaft fractures in adult patients, using open locked intramedullary nailing. PATIENTS AND METHODS: This is a prospective study which was carried out on all adult patients aged 16 years and above who presented within 2 weeks of sustaining closed femoral shaft fractures to the accident and emergency unit of a University Teaching Hospital in Nigeria from January 2013 to December 2013...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192637/predictors-of-vitamin-d-deficiency-in-predialysis-patients-with-stage-3-5-chronic-kidney-diseases-in-southern-china
#8
M Feng, J Lv, F T Huang, P F Liang, S Fu, Y C Zeng, Y Tang, A P Xu
OBJECTIVE: Vitamin D status and risk factors of Vitamin D deficiency in chronic kidney disease (CKD) patients in China have been seldom reported before. In this study, we aim to investigate serum 25-hydroxyvitamin D [25(OH)D] status and find the predictors of Vitamin D deficiency in predialysis patients with Stage 3-5 CKDs in Southern China. METHODS: In this retrospective cross-sectional study, hospitalized predialysis patients who were diagnosed of Stage 3-5 CKD and had taken measurement of serum 25(OH)D in a single center from January 2014 to June 2015 were included...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192636/assessment-of-body-perception-psychological-distress-and-subjective-quality-of-life-among-obese-and-nonobese-subjects-in-turkey
#9
N Son
BACKGROUND: Obesity can lead to psychological, social, and medical problems that may negatively affect the quality of life Aim: In our study, we aimed to evaluate the body perception, psychological distress, and subjective quality of life of obese subjects in comparison with normal weighted ones. METHODS: A total of 494 subjects, aged between 18 and 64 years, were included to the study. Patients with the body mass index (BMI) of ≥18.5-24.9 kg/m2 were assigned to the control group; BMI ≥ 30 kg/m2 were assigned to the obese patient group...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192635/is-hemorrhage-the-reason-in-crimean-congo-hemorrhagic-fever-patients-with-neurological-signs-and-symptomsa
#10
Fatma Aktaş, Zafer Özmen, Ayşegül Altunkaş, Eda Albayrak, Fazilet Duygu, Osman Demir, Zeliha Cansel Özmen
PURPOSE: Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease can result in mortality varying from 3.0% to 50.0%. In this study, we wished to discuss computed tomography (CT) findings together with clinical and laboratory findings in patients who had disease-related neurological signs. MATERIALS AND METHODS: The study included patients who were diagnosed with CCHF. Seventeen patients that had neurological signs were enrolled as the patient group. As a control group, 40 patients diagnosed with CCHF and did not have neurological signs were enrolled...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192634/the-pattern-of-significant-lesions-found-in-computerized-tomography-scan-of-recurrent-seizure-patients-at-a-center-in-enugu-nigeria
#11
A B Ezeala-Adikaibe, S C Ohaegbulam, C A Ndubuisi
INTRODUCTION: Seizures are common reasons for neurologic consultations and investigations. In the absence of magnetic resonance imaging, computerized tomography scanning of the brain is a reliable and cheaper alternative. Little is known about the pattern of brain lesions in patients with recurrent seizures in Nigeria. OBJECTIVES: To determine the pattern of significant intracerebral lesions in patients presenting with recurrent seizures in a tertiary hospital in Enugu...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192633/pattern-of-maxillofacial-surgical-conditions-in-north-central-nigeria-a-5-year-experience-of-an-indigenous-surgical-mission
#12
Seidu A Bello, Timothy Osodin, Ifeoluwa Oketade, Alwel-Brown Ibikari, Nosa Ighile, Deborah J Enebong, Paul Ekpa
BACKGROUND: Several publications have presented pattern of maxillofacial surgical conditions based on data from hospital-based studies. The objective of this study is to present the spectrum of maxillofacial surgical conditions from the perspective of a community study. METHODS: This is a prospective study of all patients seen and treated from 2011 to 2016. The information obtained included the biodata, clinical history of the disease conditions, radiological result, histopathologic result, diagnosis, and treatment records...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192632/effect-of-different-modes-of-erbium-yttrium-aluminum-garnet-laser-on-shear-bond-strength-to-dentin
#13
E Kucukyilmaz, M S Botsali, E Korkut, Y Sener, T Sari
OBJECTIVES: The aim of this study was to evaluate the effect of different surface treatments on the shear bond strength (SBS) of resin composites to dentin using total etch dentin bonding adhesives. MATERIALS AND METHODS: Sixty extracted human molars were flattened to obtain dentin surfaces. The samples were divided into three groups (n = 20): Group I: 37% phosphoric acid + optibond FL + resin composite; Group II: Erbium:yttrium aluminum garnet (Er:YAG) laser (medium short pulse [MSP] mode, 120 mJ/10 Hz) + optibond FL + resin composite; Group III: Er:YAG laser (quantum square pulse [QSP] mode, 120 mJ/10 Hz) + optibond FL + resin composite...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192631/intermittent-testicular-torsion
#14
A O Obi
OBJECTIVE: The aim of this study is to highlight the clinical characteristics of patients with intermittent testicular torsion and draw attention to this underreported condition. METHODS: Clinical and demographic data of all patients treated for intermittent testicular torsion from January 2007 to June 2015 were prospectively collected in a pro forma and analyzed. A diagnosis of intermittent torsion was made on the basis of recurrent scrotal pain, presence of abnormal testicular lie in otherwise normal testes, absence of urinary symptoms, and negative urine cultures...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192630/diagnostic-utility-of-alpha-fetoprotein-and-des-gamma-carboxyprothrombin-in-nigerians-with-hepatocellular-carcinoma
#15
Akpakip Ikpong Ette, D A Ndububa, O Adekanle, U Ekrikpo
BACKGROUND: Alpha-fetoprotein (AFP) and Des-gamma-carboxyprothrombin (DCP) have been extensively studied as biomarkers for the diagnosis of and prognostication in hepatocellular carcinoma (HCC). However there are only few reports on the clinical characteristics of hepatocellular carcinoma in relation to the combination of the two tumor markers in hepatitis B virus-related HCC. AIM: The aim of this study was to investigate the clinical characteristics of HBV-related HCC in relation to different sets of AFP and DCP values...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192629/prevalence-of-traumatic-dental-injuries-and-associated-factors-among-8-to-12-years-old-schoolchildren-in-diyarbakir-turkey
#16
E C Tumen, I Yavuz, S Kaya, E Uysal, D S Tümen, Y Ay, G Başaran, Ö Adıgüzel, Y Değer, N Laçin
BACKGROUND AND OBJECTIVES: This study aimed to assess the prevalence of traumatic injuries of the permanent incisors in public primary schoolchildren from 8 to 12 years old in South-Eastern Anatolia, Turkey. Additionally, the relationship between traumatic dental injuries, parents' education level, family income, size of incisal overjet and the presence of anterior open bite were examined. MATERIALS AND METHODS: Data were collected through oral examinations and structured interviews, and included socio-economic indicators...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192628/a-comparative-study-of-the-oral-microbiome-compositions-of-healthy-postmenopausal-premenopausal-and-prepubertal-nigerian-females-using-16s-rrna-metagenomics-methods
#17
K C Anukam, N R Agbakoba
INTRODUCTION: There is a paucity of information on the oral microbiome compositions of Nigerians, mostly due to lack of appropriate molecular techniques. In this pilot study, we sought to determine and characterize the oral bacterial compositions of "healthy" females. MATERIALS AND METHODS: Oral samples were collected from three randomly selected females aged 56, 28, and 8 years. DNA was extracted and 16S rRNA V4 region was amplified using custom-barcoded primers before sequencing with Illumina MiSeq platform...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192627/behavioural-and-anthropometric-risk-factors-for-diabetes-mellitus-among-newly-admitted-undergraduates-in-a-nigerian-university
#18
O A Adegoke, B O Emma-Okon, M K Fasanya, A O Salawu, A A Tomi-Olugbodi
BACKGROUND: Type 2 diabetes mellitus (DM) is fast becoming a global epidemic, and its prevalence is increasing in children and young adults. The aim of the study was to identify young adults who had type 2 DM or impaired fasting glucose as well as those at risk of these conditions using anthropometric data and behavioral pattern. METHODOLOGY: Two hundred and twenty newly admitted undergraduates who were randomly selected during the registration process were involved in the study...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192626/neutrophil-lymphocyte-ratio-predicts-postoperative-pain-after-orthognathic-surgery
#19
H C Turgut, M Alkan, M S Ataç, S K Altundağ, S Bozkaya, B Şimşek, B Işik, M Arslan
BACKGROUND AND AIM: Postoperative pain is well known and usually disturbing complication of surgery. Inflammation plays an important role in the development and progression of postoperative pain. We aimed to investigate possible relationship between preoperatively measured neutrophil-lymphocyte ratio (NLR) - as an inflammation marker - and postoperative analgesic demand in patients underwent orthognathic surgery. MATERIALS AND METHODS: We retrospectively investigated medical and anesthesia records of 177 patients underwent orthognathic surgery...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192625/the-force-required-to-fracture-endodontically-roots-restored-with-various-materials-as-intra-orifice-barriers
#20
E Yasa, H Arslan, B Yasa, M Akcay, M Alsancak, H Hatirli
OBJECTIVE: To evaluate the effect of various materials as intra-orifice barriers on the force required fracture roots. MATERIALS AND METHODS: One hundred-thirty five mandibular premolars were decoronated and prepared up to size #40. The root canals were filled and randomly divided into two control and seven experimental groups (n = 15), as follows: Positive control group (the intra-orifice barrier cavity was not prepared), negative control group (the intra-orifice barrier cavity was prepared, but not filled), filling using glass ionomer cement, nano-hybrid composite resin, short fiber-reinforced composite, bulk-fill flowable composite, MTA Angelus, Micro Mega MTA or Biodentine...
October 2017: Nigerian Journal of Clinical Practice
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