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Nigerian Journal of Clinical Practice

D Zhou, Q Ouyang, M Xiong, Y Zhang
Because of the similarity of the clinical symptoms, endoscopic, and pathological features, the differential diagnosis between Crohn's disease (CD) and intestinal tuberculosis (ITB) remains difficult, especially in a high-incidence area of tuberculosis (TB). Here we reported three patients with positive Ziehl-Neelsen stain in endoscopic mucosal biopsy specimens. They had a poor response to anti-TB therapy but a good response to immunosuppresses, infliximab, or surgery, and were finally diagnosed as CD. It was not clear that they were CD concomitant with mycobacteria infection or CD induced by mycobacteria infection...
October 2018: Nigerian Journal of Clinical Practice
M Agca, A Kosif
Metastatic tumors with unknown primary origin are a group of heterogeneous tumors with undetectable primary tumor site on admission. They have the common properties of rapid and aggressive progression and unpredictable metastases. They form 3%-5% of all cases with cancer and the fourth-most common cause of cancer-related deaths. The histological type of these tumors is commonly (90%) adenocarcinoma, whereas 5% are squamous cell carcinomas. Metastasis is observed in the liver, lungs, and bones. Mediastinal lymph node metastasis is extremely rare...
October 2018: Nigerian Journal of Clinical Practice
G Belakova, V Manka, E Zanova, P Racay
Background: Anti-citrullinated peptides antibodies (ACPA) are specific for rheumatoid arthritis and have been implicated in disease pathogenesis. ACPA examination is a new component of ACR/EULAR 2010 classification criteria for rheumatoid arthritis. ACPA positivity predicts a more erosive disease course with severe joint damage and extra-articular manifestations. Objectives: To evaluate the benefits of ACPA examination in patients with early undifferentiated arthritis and patients with rheumatoid arthritis...
October 2018: Nigerian Journal of Clinical Practice
C Soysal, U Ozmen
Aim: Although there are many studies in literature comparing intrauterine insemination (IUI) and timed intercourse, there are only a few studies examining the use of clomiphene citrate (CC) in ovulatory infertile patients. The aim of this study was to compare IUI following CC-induced ovulation and timed intercourse following CC-induced ovulation in ovulatory infertile patients. Methods: Hundred patients who had IUI or timed intercourse following ovulation induction (OI) via CC between 2012 and 2014 are prospectively scanned...
October 2018: Nigerian Journal of Clinical Practice
A I Ayede, F A Bello, A O Kehinde
Background: : Intestinal helminthiasis is a major public health problem in Africa. Helminthic infection in pregnant women causes loss of appetite, poor nutrient absorption, gastrointestinal impairment, iron deficiency, and iron deficiency anemia resulting in low birth weights and preterm births. The main aim of this study is to assess the prevalence of helminthic infections in pregnant women in rural and peri-urban communities of Ibadan. Materials and Methods: : A cross-sectional descriptive study was carried out at the antenatal clinics of 12 selected primary health centers and mission homes in Ibadan, Nigeria...
October 2018: Nigerian Journal of Clinical Practice
N X Chao, L Z Li, G R Luo, W G Zhong, R S Huang, R Fan, F L Zhao
Aim: To explore the use of cancer-testis antigen G antigen 1 (GAGE-1) in the diagnosis and potential therapeutic targeting of hepatocellular carcinoma (HCC), we measured the expression of GAGE-1 protein levels in HCC tissues and its serum immunoreactivity in HCC patients. Materials and Methods: We detected the expression of GAGE-1 protein in HCC by immunohistochemistry (IHC). We then analyzed the clinical significance of GAGE-1 expression in HCC with respect to clinicopathological parameters...
October 2018: Nigerian Journal of Clinical Practice
O Eroglu
Background: Although little importance is attached to hiccups, they may be associated with several diseases. The purpose of this study was to investigate the effects of gender differences on types of hiccups and the relation with diseases involved in the etiology. Materials and Methods: Patients presenting to the Kirikkale University Medical Faculty Hospital with hiccups were investigated retrospectively. Patients' age, sex, duration of hiccups, additional diseases, advanced imaging results, laboratory tests, and clinical follow-up were recorded...
October 2018: Nigerian Journal of Clinical Practice
B O Edelu, I K Ndu, O O Igbokwe, O N Iloh
Introduction: Severe malaria remains one of the leading causes of morbidity and mortality in sub-Saharan Africa and parts of Asia despite several efforts in prevention and management. The prevalence and pattern of presentation may vary from one location to another and from one age group to another. Objectives: This study was undertaken to review the prevalence and pattern of severe malaria among children presenting in the two tertiary hospitals in Enugu, south-east Nigeria...
October 2018: Nigerian Journal of Clinical Practice
Rufina N B Ayogu, Tochukwu P Onah
Background: Micronutrient deficiencies are public health problems among school children. Food-to-food fortification may reduce the prevalence of these deficiencies. Aim: To assess the impact of cowpea (Vigna sinensis) fortified cookies on weight, height, body mass index (BMI), hemoglobin, serum vitamin A, and zinc status of primary school children aged 6-12 years. Methods: A randomized single-blind controlled trial was conducted for 4 weeks among 17 pupils who were voluntarily recruited and randomly assigned to experimental (Group A) and control (Group B) groups...
October 2018: Nigerian Journal of Clinical Practice
M Alkan, F D Erkent, Ali Celik, A Gokce, M Arslan, Y Unal
Background and Purpose: Postoperative pain is a significant problem in thoracotomy patients. Our aim in this study was to investigate the relationship between postoperative pain and neutrophil-to-lymphocyte ratio (NLR) which is a marker of acute inflammatory response. Materials and Methods: Thoracic epidural or intravenous analgesia was administered to thoracotomy patients who elected to undergo a planned surgery. Patients were divided into two groups according to the analgesia method applied postoperatively...
October 2018: Nigerian Journal of Clinical Practice
N Z Ikeri, A O Akinjo, O O Ajayi, A A Banjo
Background: : The effective management of patients with cancer is predicated on the right diagnoses and other relevant parameters included in the pathology report. This is particularly important in soft tissue pathology where arriving at the right diagnosis is often challenging. The aim of this study, therefore, was to perform an audit of sarcoma diagnosis and reporting in our institution. Methods: Slides of soft tissue sarcomas diagnosed in our institution over a 5-year period were reviewed with specialist soft tissue pathologists...
October 2018: Nigerian Journal of Clinical Practice
R Guven, Ali Haydar Akca, C Caltili, M I Sasmaz, E K Kaykisiz, S Baran, L Sahin, A Ari, G Eyupoglu, V Kirpat
Introduction: Computed tomography (CT) interpretation in the emergency department is one of the vital issues that should be carried out rapidly and accurately. The objective of this study was to examine the interpretation accuracy of emergency physicians (EPs) regarding CT scans at the emergency department for traumatic and nontraumatic purposes. Materials and Methods: The study that was carried out as a prospective, observational study was completed at four centers during 1 year...
October 2018: Nigerian Journal of Clinical Practice
D Odabasi, E Oruc, G Duruk
Objectives: The purpose of this in vitro study was to investigate the effect of three different enamel surface conditioning procedures on the bonding strength of two resin-based filled fissure sealants. Material and Methods: Freshly extracted, 48 third molar teeth were used in this study. Teeth were randomly divided into three main groups as the phosphoric acid etched, erbium: Yttrium-aluminum-garnet (ER: YAG) laser etched, and the phosphoric acid plus ER: YAG laser-etched groups...
October 2018: Nigerian Journal of Clinical Practice
M Ulker, H E Ulker, M S Botsali, A Dundar
Objectives: The aim of this study was to evaluate the efficacy of using erbium, chromium-doped:yttrium scandium gallium garnet (Er,Cr:YSGG) laser-treated dentine in a dentine barrier test device. Materials and Methods: The test materials (G-Bond™ and Vitrebond™) were applied onto laser-treated or laser-untreated dentine discs. After 24 h of exposure with perfusion of the test chamber, cell survival was evaluated based on enzyme activity and compared to a nontoxic control material...
October 2018: Nigerian Journal of Clinical Practice
S E Guney, C Araz, R E Tirali, S B Cehreli
Purpose: The study aimed to investigate dental anxiety and oral health-related quality of life among children undergoing dental rehabilitation under general anesthesia (GA) and intravenous sedation (IVS). Materials and Methods: Participants were 99 healthy children aged 3-5 or 6-12 years operated under GA or IVS. Dental anxiety before treatment and 1 month postoperatively were measured using the Frankl behavior scale (FBS), the venham picture test (VPT), the early childhood oral health impact scale (ECOHIS), and the children's fear survey schedule-dental subscale (CFSS-DS)...
October 2018: Nigerian Journal of Clinical Practice
L Tomak, O Midik
Background: Rasch model is a useful method for developing a new scale. This study aims to determine the fitting between data obtained from answers for a portfolio anxiety scale and Rasch model and describes how the scale can be modified to increase the fitting through different steps. Materials and Methods: A portfolio scale was applied to 171 students of the Faculty of Medicine, Ondokuz Mayis University. The partial credit model was used, and fit statistics were assessed to determine the fitting of the data to Rasch model...
October 2018: Nigerian Journal of Clinical Practice
P Oyar, F A Sana, B Nasseri, R Durkan
Purpose: The aim of this study was to investigate the effect of gold nanoparticle on the flexural strength of polymethyl methacrylate (PMMA). Materials and Methods: PMMA specimens (65 mm × 10 mm × 3.3 mm) containing different sizes (45 nm, 55 nm, and 65 nm) and concentrations (0.05% and 0.2%) of gold nanoparticles were prepared, along with a control group containing no added nanoparticles. Flexural strength of all specimens was measured, and one-way ANOVA and Tukey-Kramer post hoc multiple comparisons tests were performed to identify statistical differences between groups...
October 2018: Nigerian Journal of Clinical Practice
B Kesim, A K Burak, Y Ustun, E Delikan, A Gungor
Objective: The objective of this study is to compare the effectiveness of final irrigation with chitosan, ethylenediaminetetraacetic acid (EDTA), and citric acid (CA) on a resin-based sealer (AH plus sealer [Dentsply DeTrey, Konstanz, Germany]) penetration into dentinal tubules using confocal laser scanning microscopy. Materials and Methods: Seventy recently extracted human mandibular premolars were instrumented and irrigated with sodium hypochlorite (NaOCl), then divided into four groups according to the final irrigation regimen used: (1) the EDTA group: 17% EDTA + 2...
October 2018: Nigerian Journal of Clinical Practice
N Tas, T Noyan, O Yagan, V Hanci, E Canakci
Aims: This research aims to investigate whether there is a correlation between the respiratory complications occurring in patients under general anesthesia and preoperative Vitamin D levels. Settings and Design: The study was a prospective observational study. Materials and Methods: This study included 95 adult cases. The cases had total 25-hydroxyvitamin D (25OHD) levels identified in blood samples before the operation. Patients given routine general anesthesia and were assessed in terms of respiratory complications during anesthesia induction, extubation, anesthesia recovery, and the first 24-h postoperative...
October 2018: Nigerian Journal of Clinical Practice
T T Koca, M Seyithanoglu, S Sagiroglu, E Berk, H Dagli
Aim: Central sensitization-related neuroaudiological symptoms are frequently seen in patients with fibromyalgia syndrome (FMS). This study aimed to evaluate the audiological signs and symptoms in patients with FMS and explore their relationship with oxidative stress markers. Methods: This prospective controlled cross-sectional study compared the serum myeloperoxidase, superoxide dismutase, glutathione peroxidase (GPx), nitric oxide (NO), and malondialdehyde (MDA) concentrations in 44 patients with FMS diagnosed according to the 2010 American College of Rheumatology criteria and 44 healthy volunteers...
October 2018: Nigerian Journal of Clinical Practice
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