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Canadian Journal of Diabetes

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https://www.readbyqxmd.com/read/29284562/optimizing-glycemic-control-in-adults-with-type-1-or-type-2-diabetes-attending-a-multidisciplinary-foot-clinic
#1
Devin Betsch, Zhiwei Gao, Gerry Mugford, Susan McGrath-Terry, Gordon Dow
OBJECTIVES: To determine the impact of a diabetes nurse educator (DNE) on glycemic control in a multidisciplinary diabetes foot (MDF) clinic. METHODS: A prospective cohort trial to measure the impact of a DNE on glycemic control was conducted in an MDF clinic. Change in glycated hemoglobin (A1C) levels over time was measured against the percentage of patient visits (PPVs) accompanied by a glucose meter and/or diary. RESULTS: Increasing PPVs were significantly associated with decline in A1C levels in females...
December 25, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29284561/does-type-2-diabetes-mellitus-affect-the-healing-of-bell-s-palsy-in-adults
#2
Sultan Şevik Eliçora, Duygu Erdem
OBJECTIVES: Bell's palsy (BP) is defined as an acute facial weakness of unknown cause. Many factors affecting the healing of BP have been identified; 1 factor commonly considered relevant is the presence of type 2 diabetes mellitus. Our aim was to investigate the effects of diabetes on the healing of BP. METHODS: Sixty patients with BP were followed up for 1 to 3 years and were divided into 2 groups, those with and those without type 2 diabetes. All were prescribed prednisone (initially 1 mg/kg per day, with a tapered dose reduction) and acyclovir (200 mg orally every 4 h, 5 times daily, for 5 days)...
December 25, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29282200/is-youtube-useful-as-a-source-of-health-information-for-adults-with-type-2-diabetes-a-south-asian-perspective
#3
Amanda Y Leong, Ravina Sanghera, Jaspreet Jhajj, Nandini Desai, Bikramjit Singh Jammu, Mark J Makowsky
OBJECTIVES: To investigate the content, quality and popularity of information about type 2 diabetes available on YouTube. METHODS: We searched YouTube with the terms Diabetes, Diabetes type 2, Diabetes South Asians, Diabetes Punjabi and Diabetes Hindi to identify videos concerning type 2 diabetes. A team of health-care providers independently classified the first 20 videos from each search as useful, misleading, or personal experience, rated them on a 5-point global quality scale (GQS) and categorized their content on a 26-point scale in duplicate...
December 25, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29282199/comparison-of-hemoglobin-a1c-results-based-on-at-home-and-in-lab-dried-blood-spot-sampling-to-routine-venous-blood-sampling-in-lab-in-adult-patients-with-type-1-or-type-2-diabetes
#4
Thomas G Elliott, Kent C Dooley, Mira Zhang, Harlan S D Campbell, Darby J S Thompson
OBJECTIVES: Regular measurement of glycated hemoglobin (A1C) is logistically demanding. Home blotter-paper collection offers an alternative. This study tested the viability of at-home blotter-paper A1C measurement. METHODS: Objective: compare accuracy of A1C levels collected on blotter paper at home (home-blotter) and blotter-paper collection in laboratory (lab-blotter) with venous A1C (routine measurement). Agreement was assessed by Pearson correlation, Lin concordance correlation coefficient (CCC), positive and negative predictive values (PPVs, NPVs) and Bland-Altman plots and associated statistics...
December 25, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29277343/the-divergent-cardiovascular-effects-of-ace-inhibitors-and-arbs-in-patient-with-type-2-diabetes-mellitus
#5
Martin H Strauss, Alistair S Hall
The renin angiotensin aldosterone system (RAAS) plays a central role in the pathophysiology of hypertension and vascular disease. Angiotensin-converting enzyme inhibitors (ACEi's) suppress angiotensin II (ANG II) concentrations, whereas angiotensin II type 1 (AT1) receptor blockers (ARBs) block the binding of ANG II to AT1 receptors. ACEi's and ARBs are both effective antihypertensive agents and produce similar risk reductions for stroke, a blood pressure-dependent phenomenon. ACEi's also reduce the risk for myocardial infarction (MI) and all-cause mortality in high-risk hypertensive patients as well as in people with diabetes, vascular disease and congestive heart failure...
December 22, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29273294/thresholds-and-targets-for-hypertension-management-of-type-2-diabetes-mellitus-remain-at-130-80%C3%A2-mmhg-what-s-the-evidence
#6
REVIEW
Niharika Shahi, Sheldon W Tobe
Hypertension and diabetes are common comorbidities and are both modifiable risk factors for cardiovascular disease and death. Lowering blood pressure reduces target organ damage and prevents cardiovascular disease outcomes. The harmonized Canadian clinical practice guidelines for managing hypertension in people with diabetes provides health-behaviour advice and medical therapy recommendations for a threshold blood pressure of 130/80 mmHg and above and to target blood pressure to below 130/80 mmHg. We have reviewed the studies supporting these recommendations and others, and they appear to be at odds with the guidelines, including those for elderly people and patients with pre-existing cardiovascular disease...
December 20, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29229313/emerging-role-of-adipocytokines-in-type-2-diabetes-as-mediators-of-insulin-resistance-and-cardiovascular-disease
#7
REVIEW
Ravindran Jaganathan, Rajeswari Ravindran, Sugapriya Dhanasekaran
Adipose tissue is an enormously active endocrine organ, secreting various hormones, such as adiponectin, leptin, resistin and visfatin, together with classical cytokines, such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6). All these adipocytokines plays significant roles in the regulation of energy metabolism, glucose and lipid metabolism, reproduction, cardiovascular function and immunity. Adipocytokines are significantly regulated by nutritional status and can directly influence other organ systems, including brain, liver and skeletal muscle...
December 8, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29217217/antioxidant-role-of-vitamin-d-in-mice-with-alloxan-induced-diabetes
#8
Sarah Iqbal, Saman Khan, Imrana Naseem
OBJECTIVES: The discovery of vitamin D receptors has revolutionized the understanding of vitamin D biology, which is now thought to influence a wide array of cell pathways. The antihyperglycemic actions of vitamin D involving calcium metabolism have been widely discussed, but studies are now suggesting a possibility of vitamin D-induced amelioration of oxidative stress. Despite its significance in disease pathogenesis, oxidative status remains poorly investigated with respect to vitamin D treatment in the biology of diabetes mellitus...
December 4, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29212609/effect-of-combined-exercise-versus-aerobic-only-training-on-skeletal-muscle-lipid-metabolism-in-a-rodent-model-of-type1-diabetes
#9
Michelle S Dotzert, Matthew W McDonald, Michael R Murray, J Zachary Nickels, Earl G Noble, C W James Melling
OBJECTIVES: Abnormal skeletal muscle lipid metabolism is associated with insulin resistance in people with type 1 diabetes. Although lipid metabolism is restored with aerobic exercise training, the risk for postexercise hypoglycemia is increased with this modality. Integrating resistance and aerobic exercise is associated with reduced hypoglycemic risk; however, the effects of this exercise modality on lipid metabolism and insulin resistance remain unknown. We compared the effects of combined (aerobic + resistance) versus aerobic exercise training on oxidative capacity and muscle lipid metabolism in a rat model of type 1 diabetes...
December 4, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29212608/clinical-islet-transplantation-for-type-1-diabetes-in-canada-referral-patterns-and-eligibility-assessment
#10
Ying Ling, Aashna Gill, Richard Oram, A M James Shapiro, Peter Senior
OBJECTIVES: Careful selection for clinical islet transplantation (CIT) is required because of limited organ supply and the risks for lifelong immunosuppression. However, the indications for this novel treatment may not be widely known, and selection criteria continue to evolve. We sought to describe the pattern of referrals to our centre and the most common factors determining eligibility for CIT. METHODS: We performed a retrospective chart review of all applications for CIT received at the University of Alberta between May 2009 and April 2012...
December 4, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29129456/a-canadian-cross-sectional-survey-on-psychosocial-supports-for-people-living-type-1-or-2-diabetes-health-care-providers-awareness-capacity-and-motivation
#11
Jennica Nichols, Michael Vallis, Stephanie Boutette, Carolyn Gall Casey, Catherine H Yu
OBJECTIVES: Addressing psychosocial issues is critical for diabetes self-management. This work explores health-care professionals' (HCPs') 1) perceived relevance of various psychosocial issues in diabetes management and 2) confidence in working on these issues within their services. METHODS: An online cross-sectional survey was developed based on the Capacity-Opportunity-Motivation Behaviour Model. It assessed self-rated confidence in supporting patients with psychosocial issues (capability), perceived relevance of these issues (motivation) and facilitators of skill development (opportunity)...
November 9, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29129455/plasma-palmitoyl-carnitine-ac16-0-is-a-marker-of-increased-postprandial-nonesterified-incomplete-fatty-acid-oxidation-rate-in-individuals-with-type-2-diabetes
#12
Fatima-Zahra Bouchouirab, Mélanie Fortin, Christophe Noll, Jean Dubé, André C Carpentier
OBJECTIVES: Enhanced mitochondrial fatty acid utilization is known to increase radical oxidative stress and induce insulin resistance. An increased level of plasma acylcarnitine (AC) has been proposed to indicate mitochondrial energy substrate overload, a possible mechanism leading to insulin resistance. The aim of our study was to determine fasting and postprandial plasma acetyl-carnitine (AC2:0), palmitoyl-carnitine (AC16:0), oleoyl-carnitine (AC18:1) and linoleoyl-carnitine (AC18:2) levels and their relationships with plasma nonesterified fatty acid appearance and oxidation rates and insulin sensitivity in participants with type 2 diabetes and normoglycemic offspring of 2 parents with type 2 diabetes (FH+) compared to healthy participants without family histories of type 2 diabetes (FH-)...
November 9, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29128304/symptoms-of-mental-illness-and-their-impact-on-managing-type-2-diabetes-in-adults
#13
Adriana Cimo, Carolyn S Dewa
OBJECTIVES: People with mental illnesses are more likely to experience diabetes-related complications that can reduce life expectancy by 10 to 15 years. Diabetes management and outcomes can be improved when lifestyle interventions addressing healthful eating habits and physical activity use content tailored to the learning needs of individuals or groups. Understanding the challenges that prevent adherence to diabetes recommendations can start to inform the design of tailored diabetes education care...
November 8, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29128303/the-mountain-of-health-the-perceptions-and-perceived-expectations-of-youth-living-with-type-2-diabetes-in-winnipeg-manitoba-canada-through-a-grounded-theory-study
#14
Elizabeth Huynh
OBJECTIVE: The objective of this study was to explore youth's perceptions of diabetes management. METHODS: The study included 8 Manitoban youth with type 2 diabetes (n=7 girls). Each youth participated in a semistructured interview in person, via Skype or over the phone. The constructivist grounded theory methodologic approach guided the analysis of the data. RESULTS: Discussions about diabetes and health and its management revealed 2 viewpoints: 1) youth's perceptions and 2) youth's perceptions of health-care providers' expectations...
November 8, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29103904/effects-of-diabetes-mellitus-on-cognitive-decline-in-patients-with-alzheimer-disease
#15
LETTER
Tomoyuki Kawada
No abstract text is available yet for this article.
November 3, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29224636/effects-of-pharmacy-based-interventions-on-the-control-and-management-of-diabetes-in-adults-a-systematic-review-and-meta-analysis
#16
REVIEW
Mohsen Yaghoubi, Kerry Mansell, Hassanali Vatanparastc, Megan Steeves, Wu Zeng, Marwa Farag
OBJECTIVES: The aim of this systematic review and meta-analysis was to evaluate the effects of pharmacy-based interventions on clinical outcomes associated with diabetes-related complications as well as on nonclinical outcomes in people with diabetes. METHODS: We searched 4 main databases (MEDLINE, EMBASE, CINAHL and Cochrane Central Register of Controlled Trials) for studies that considered clinical and nonclinical outcomes of pharmacy-based interventions among people with diabetes...
December 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29224635/community-pharmacists-perspectives-of-a-decision-aid-for-managing-type-2-diabetes-in-ontario
#17
Lee Verweel, Michael R Gionfriddo, Lori MacCallum, Lisa Dolovich, Zahava R S Rosenberg-Yunger
OBJECTIVES: Decision aids are tools designed to help patients make choices about their health care. We explored pharmacists' perceptions of an evidence-based diabetes decision aid developed by the Mayo Clinic, Diabetes Medication Choice (DMC). Using DMC as a reference, we aimed to explore pharmacists' perspectives on decision aids, their place in a community pharmacy setting and the implementing of a decision aid, such as DMC, in Ontario. METHODS: We used semistructured interviews with a convenience sample of community pharmacists from Ontario...
December 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29224634/creation-of-a-diabetes-pharmacists-network-in-canada
#18
Lori MacCallum, Gary F Lewis
No abstract text is available yet for this article.
December 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29224633/over-the-counter-medicines-and-diabetes-care
#19
Jeff Taylor
OBJECTIVES: People with diabetes turn to over-the-counter (OTC) medicines for many ailments. The focus of this brief review is the impact common OTC medicines might have on this group of patients. METHODS: Three types of OTC medicines were selected as most deserving of attention: 3 herbal agents, nonsteroidal anti-inflammatory drugs (NSAIDs) and cough/cold products. Existing literature was used to determine precautions that might be in order. RESULTS: Herbal/natural agents with the potential to impact blood sugar have been identified in various reports...
December 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29224632/pharmacy-practice-and-diabetes-care
#20
EDITORIAL
Scot H Simpson, Lori MacCallum, Kerry Mansell
No abstract text is available yet for this article.
December 2017: Canadian Journal of Diabetes
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