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Canadian Journal of Diabetes

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https://www.readbyqxmd.com/read/28803822/egg-consumption-and-cardiovascular-risk
#1
LETTER
J David Spence
No abstract text is available yet for this article.
August 10, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28803821/regarding-insulin-initiation-in-type-2-diabetes-mellitus-and-the-risk-for-hypoglycemia
#2
LETTER
Jan Brož, Brian M Frier
No abstract text is available yet for this article.
August 10, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28803820/titration-a-randomized-study-to-assess-2-treatment-algorithms-with-new-insulin-glargine-300-units-ml
#3
Jean-François Yale, Lori Berard, Mélanie Groleau, Pasha Javadi, John Stewart, Stewart B Harris
OBJECTIVE: It was uncertain whether an algorithm that involves increasing insulin dosages by 1 unit/day may cause more hypoglycemia with the longer-acting insulin glargine 300 units/mL (GLA-300). The objective of this study was to compare safety and efficacy of 2 titration algorithms, INSIGHT and EDITION, for GLA-300 in people with uncontrolled type 2 diabetes mellitus, mainly in a primary care setting. METHODS: This was a 12-week, open-label, randomized, multicentre pilot study...
August 10, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28800932/is-type-2-diabetes-associated-with-impaired-capacity-for-weight-loss
#4
Ghadi Antoun, Majid Nikpay, Ruth McPherson, Mary-Ellen Harper, Robert Dent
No abstract text is available yet for this article.
August 8, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28797890/developing-and-implementing-a-food-insecurity-screening-initiative-for-patients-living-with-diabetes
#5
Brittany Thomas, Sandra Fitzpatrick, Souraya Sidani, Enza Gucciardi
OBJECTIVES: Routine food insecurity screening is recommended in diabetes care to inform more tailored interventions that better support diabetes self-management among food-insecure patients. This pilot study explored the acceptability and feasibility of a food insecurity screening initiative within a diabetes care setting in Toronto. METHODS: A systematic literature review informed the development of a food insecurity screening initiative to help health-care providers tailor diabetes management plans and better support food-insecure patients with type 2 diabetes...
August 7, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28797889/insights-into-the-recognition-and-management-of-sglt2-inhibitor-associated-ketoacidosis-it-s-not-just-euglycemic-diabetic-ketoacidosis
#6
Stephanie Dizon, Erin J Keely, Janine Malcolm, Amel Arnaout
No abstract text is available yet for this article.
August 7, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28757254/framing-obesity-as-a-health-issue-differences-in-public-and-professional-perceptions-between-canada-and-the-united-states
#7
Bonnie L Kuehl, Sara F L Kirk, Nathalie Dumas, Theodore K Kyle
No abstract text is available yet for this article.
July 28, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28754435/children-with-type-1-diabetes-have-delayed-flow-mediated-dilation
#8
Sarveshinee Pillay, Jemma Anderson, Jennifer Couper, Oana Maftei, Roger Gent, Alexia Sophie Peña
OBJECTIVES: Children with type 1 diabetes have accelerated atherosclerosis with early endothelial dysfunction as measured by reduced flow-mediated dilation (FMD) at 60 seconds postischemic stress (early FMD). Delayed dilation may also occur in the presence of cardiovascular risk factors and may be a more sensitive marker. No data exist that evaluate FMD beyond 60 seconds (delayed FMD) in children with type 1 diabetes. We aimed to compare early and delayed FMD in children with type 1 diabetes and in healthy children...
July 25, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28739347/association-of-vitamin-d-receptor-gene-polymorphism-in-patients-with-type-2-diabetes-in-the-kashmir-valley
#9
Rawoof Malik, Rabia Farooq, Promela Mehta, Sheikh Ishaq, Insha Din, Parvaiz Shah, Sabhiya Majid
OBJECTIVES: Approx 1 billion people across various ethnic and age groups have vitamin D deficiency. The high prevalence of such a deficiency is an imperative public health issue because hypovitaminosis D is an autonomous risk factor for mortality in the general population. Beyond bone integrity and calcium homeostasis, it is involved in numerous physiologic and pathologic processes. The role of vitamin D in the pathogenesis and prevention of type 2 diabetes mellitus has sparked universal interest...
July 21, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28734952/potential-predictive-role-of-lipid-peroxidation-markers-for-type-2-diabetes-in-the-tunisian-population
#10
Houda Bouhajja, Faten Hadj Kacem, Rania Abdelhedi, Marwa Ncir, Jordan D Dimitrov, Rim Marrakchi, Kamel Jamoussi, Ahmed Rebai, Abdelfattah El Feki, Mohamed Abid, Hammadi Ayadi, Srini V Kaveri, Mouna Mnif-Feki, Noura Bougacha-Elleuch
OBJECTIVES: We evaluated the potential clinical relevance of malondialdehyde (MDA) and autoantibodies to copper oxidized low-density lipoprotein (CuOx-LDL) in type 2 diabetes occurrence. METHODS: This cross-sectional study enrolled 69 normoglycemic subjects, 18 prediabetic patients and 108 type 2 diabetes patients. MDA concentration was assessed spectrophotometrically. Plasma IgG, IgA and IgM levels to CuOx-LDL were determined by ELISA. RESULTS: Plasma MDA levels were considerably higher in obese, prediabetic and type 2 diabetes subjects compared to controls...
July 19, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28734951/emergency-department-management-of-diabetic-ketoacidosis-and-hyperosmolar-hyperglycemic-state-national-survey-of-attitudes-and-practice
#11
Alexandra L Hamelin, Justin W Yan, Ian G Stiell
OBJECTIVES: In 2013, the Association, now Diabetes Canada, published national clinical practice guidelines for the effective management of diabetic ketoacidosis and hyperosmolar hyperglycemic states in adults. We sought to determine emergency physician compliance rates and attitudes toward these guidelines and to identify potential barriers to their use in Canadian emergency departments. METHODS: An online survey consisting of questions related to the awareness and use of the Canadian Diabetes Association 2013 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada was distributed to 500 randomly selected members of the Canadian Association of Emergency Physicians...
July 19, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28728928/gtf-231-a-mixture-of-gymnemic-acid-trigonelline-and-ferulic-acid-significantly-ameliorates-oxidative-stress-in-experimental-type-2-diabetes-in-rats
#12
Roshana Devi Vellai, Sharmila Chandiran, Subramanian Sorimuthu Pillai
OBJECTIVES: According to a report by the United States National Health and Nutrition Examination Survey, nearly 60% of patients with diabetes have more than one complication caused by chronic diabetes. Type 2 diabetes is a multifactorial metabolic disorder that accounts for more than 95% of people with diabetes and usually requires multitargeted therapeutic interventions. It arises due to insufficient insulin secretion or its action or both. Recently, we reported that the oral administration of gymnemic acid, trigonelline and ferulic acid in the ratio of 2:3:1 (GTF-231), a mixture of 3 phytoingredients at a concentration of 300 mg/kg body weight significantly improved the glucose homeostasis in rats with low-dose streptozotocin-induced type 2 diabetes that were fed with high-fat diet...
July 17, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28689705/response-to-the-letter-to-the-editor-from-dr-kawada-depressive-symptoms-diabetes-distress-and-serum-hemoglobin-a1c-in-south-asians-with-type-2-diabetes-mellitus-living-in-canada
#13
LETTER
https://www.readbyqxmd.com/read/28689704/glycated-hemoglobin-albuminuria-and-surrogate-markers-of-macrovascular-disease-the-guangzhou-biobank-cohort-study-cardiovascular-disease-subcohort
#14
Konstantinos A Toulis, Chao Q Jiang, Karla Hemming, Krishnarajah Nirantharakumar, Kar K Cheng, Tai H Lam, G Neil Thomas
OBJECTIVES: To explore the clinical utility of glycated hemoglobin (A1C) levels as an early marker of albuminuria, macrovascular disease and subclinical cardiovascular disease in comparison to fasting and postprandial glucose levels in a well-characterized Chinese population with no history of diabetes. METHODS: The study population consisted of 1223 individuals who were enrolled in the Guangzhou Biobank Cohort Study, Cardiovascular Disease Subcohort, and who had undergone oral glucose tolerance tests...
July 6, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28684249/predictors-of-serum-adiponectin-in-patients-with-prediabetes-and-type-2-diabetes
#15
LETTER
Tomoyuki Kawada
No abstract text is available yet for this article.
July 3, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28673757/anti-inflammatory-anti-apoptotic-and-pro-proliferative-effects-of-vitis-vinifera-seed-ethanolic-extract-in-the-liver-of-streptozotocin-nicotinamide-induced-diabetes-in-male-rats
#16
Nelli Giribabu, Kamarulzaman Karim, Eswar Kumar Kilari, Normadiah M Kassim, Naguib Salleh
OBJECTIVES: Consumption of Vitis vinifera seed has been reported to ameliorate liver pathology in diabetes mellitus; however, the mechanisms underlying its effects remain unknown. In this study, the anti-inflammatory, anti-apoptotic and pro-proliferative effects of the ethanolic seed extract of V. vinifera (VVSEE) in the liver in cases of diabetes were identified. METHODS: Adult male rats with streptozotocin-nicotinamide-induced diabetes were given 50, 100 or 200 mg/kg body weight VVSEE orally for 28 days...
June 30, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28662968/adherence-to-guidelines-for-inpatient-pharmacologic-management-of-type-2-diabetes-and-glycemic-outcomes
#17
Resheed Alkhiari, Hussain Alzayer, Jafar Aljazeeri, Thuva Vanniyasingam, Zubin Punthakee
OBJECTIVES: Diabetes is often poorly managed in hospitals. This study assessed the level of adherence to current Canadian practice guidelines for inpatient pharmacologic management of type 2 diabetes and whether it affected the frequency of hyperglycemia or hypoglycemia. METHODS: Retrospectively, we assessed the first 3 days of routine inpatient capillary blood glucose measurement (CBGM) records for hyperglycemia (>8 mmol/L fasting, >10 mmol/L nonfasting) and hypoglycemia (<4 mmol/L) in adults with drug-treated type 2 diabetes admitted to internal medicine without metabolic decompensation or nil per os (NPO) status at 2 hospitals during October through December 2014...
June 26, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28662967/low-hepcidin-in-diabetes-mellitus-examining-the-molecular-links-and-their-clinical-implications
#18
REVIEW
Driton Vela, Ramadan B Sopi, Mitko Mladenov
The relationship between iron and glucose metabolism has been evidenced strongly, but the molecular mediation of this connection is just being revealed. The discovery of hepcidin as the prime controller of iron metabolism has paved the way for understanding the main actors behind this mediation. Recent data suggest that insulin therapy and probably other diabetes drugs can influence hepcidin production, thus influencing the iron load in cells. Correcting iron load through hepcidin expression could be a novel and important mechanism of action of antidiabetes drugs...
June 26, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28648765/adherence-to-diabetes-dietary-guidelines-assessed-using-a-validated-questionnaire-predicts-glucose-control-in-individuals-with-type-2-diabetes
#19
Gayathiri Durai Raj, Zohre Hashemi, Diana C Soria Contreras, Stephanie Babwik, Denise Maxwell, Rhonda C Bell, Catherine B Chan
OBJECTIVES: The purpose of this study was to determine predominant deviations from Canadian Diabetes Association (CDA) nutrition therapy guidelines for Canadians with type 2 diabetes as a prelude to developing relevant interventions. We hypothesized that lack of adherence to these guidelines would be associated with higher glycated hemoglobin (A1C) levels. METHODS: A cross-sectional trial was conducted to evaluate associations between dietary adherence to CDA and Health Canada guidelines and blood glucose control...
June 22, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28647295/associations-between-sleep-habits-and-dysglycemia-in-us-adults-a-cross-sectional-analysis
#20
Katherina C Chojnacki, Thirumagal Kanagasabai, Michael C Riddell, Chris I Ardern
OBJECTIVES: To examine the independent and joint associations between sleep duration and quality with glycated hemoglobin (A1C) levels and dysglycemia in non-institutionalized adults living in the United States. METHODS: Data from the United States National Health and Nutrition Examination Survey (2005-2008) were used (N=9478; ≥20 years). Information on sleep quantity and quality were derived from the Sleep Disorders Questionnaire and used to classify sleep quality as good, fair, poor, or very poor...
June 21, 2017: Canadian Journal of Diabetes
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