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Canadian Journal of Diabetes

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https://www.readbyqxmd.com/read/28863979/computer-simulation-model-to-train-medical-personnel-on-glucose-clamp-procedures
#1
Pooya Maghoul, Benoit Boulet, Annie Tardif, Ahmad Haidar
OBJECTIVE: A glucose clamp procedure is the most reliable way to quantify insulin pharmacokinetics and pharmacodynamics, but skilled and trained research personnel are required to frequently adjust the glucose infusion rate. A computer environment that simulates glucose clamp experiments can be used for efficient personnel training and development and testing of algorithms for automated glucose clamps. METHODS: We built 17 virtual healthy subjects (mean age, 25±6 years; mean body mass index, 22...
August 29, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28843474/serum-adiponectin-in-prediabetes-and-type-2-diabetes-mellitus
#2
LETTER
Anindita Banerjee, Vineet Kumar Khemka
No abstract text is available yet for this article.
August 23, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28843473/choosing-the-best-therapy-for-your-patients-in-today-s-diabetes-world
#3
EDITORIAL
Sara J Meltzer, Jean-François Yale
No abstract text is available yet for this article.
August 23, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28843472/egg-consumption-and-cardiovascular-risk
#4
LETTER
Caroline Richard, Catherine J Field, Rene L Jacobs, Maria Ricupero
No abstract text is available yet for this article.
August 23, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28843471/should-the-clinical-criteria-for-suspecting-glucokinase-mutation-related-hyperglycemia-mody-2-be-revisited-during-pregnancy
#5
Carl-Hugo Lachance, Michel Baillargeon
No abstract text is available yet for this article.
August 23, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28843470/pediatric-type-1-diabetes-patients-and-caregivers-perceptions-of-glycemic-control
#6
Elizabeth Rosolowsky, Maryna Yaskina, Robert Couch
OBJECTIVES: (1) to describe pediatric patients with T1D and their caregivers' perceptions of measures of glycemic control (hemoglobin [A1C] and blood glucose [BG] levels) and (2) to determine the relationship between patients' and caregivers' perceptions of measures of glycemic control with actual A1C levels and adherence to diabetes self-care behaviors. METHODS: Patients (8 to 18 years) with T1D and caregivers completed questionnaires that queried their perceptions of (1) what the A1C level assesses, (2) the ideal A1C target, and (3) the ideal BG range...
August 23, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28843469/a-genotype-first-approach-for-clinical-and-genetic-evaluation-of-wolcott-rallison-syndrome-in-a-large-cohort-of-iranian-patients-with-neonatal-diabetes
#7
Farzaneh Abbasi, Maryam Habibi, Samaneh Enayati, Fatemeh Bitarafan, Maryam Razzaghy-Azar, Aria Sotodeh, Sima Parvizi Omran, Reza Maroofian, Mahsa M Amoli
OBJECTIVE: Wolcott-Rallison syndrome (WRS) is an extremely rare autosomal recessive condition, characterized by permanent neonatal diabetes mellitus (PNDM) associated with skeletal dysplasia, growth retardation and liver dysfunction. WRS is caused by biallelic mutations in the gene encoding eukaryotic translation initiation factor 2alpha kinase 3 (EIF2AK3). METHODS: As part of a comprehensive study on clinical and genetic investigation of neonatal diabetes in an Iranian population, 60 unrelated Iranian subjects referred with PNDM were analyzed...
August 23, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28826695/natural-health-products-and-diabetes-a-practical-review
#8
REVIEW
Candace Necyk, Leyanna Zubach-Cassano
The prevalence of natural health product (NHP) use in Canada is extensive. Patients with chronic diseases, including diabetes, use NHPs at a higher rate than the general population. Many NHPs exert hypoglycemic effects, among other effects relevant to diabetes management. To provide a practical, clinical review of NHPs with such effects targeted to pharmacists, a literature search was performed to collect data on the efficacy and safety profiles of 10 commonly used NHPs that exert antidiabetic properties. The following NHPs are included in this clinical review: alpha-lipoic acid, chromium, magnesium, bitter melon, cinnamon, fenugreek, gymnema, milk thistle, Reishi mushroom and white mulberry...
August 18, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28822778/diabetes-care-program-of-nova-scotia-celebrating-25-years-of-improving-diabetes-care-in-nova-scotia
#9
REVIEW
Jennifer I Payne, Margaret J Dunbar, Pamela Talbot, Meng H Tan
The Diabetes Care Program of Nova Scotia (DCPNS)'s mission is "to improve, through leadership and partnerships, the health of Nova Scotians living with, affected by, or at risk of developing diabetes." Working together with local, provincial and national partners, the DCPNS has improved and standardized diabetes care in Nova Scotia over the past 25 years by developing and deploying a resourceful and collaborative program model. This article describes the model and highlights its key achievements. With balanced representation from frontline providers through to senior decision makers in health care, the DCPNS works across the age continuum, supporting the implementation of national clinical practice guidelines and, when necessary, developing provincial guidelines to meet local needs...
August 16, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28822777/managing-the-course-of-diabetic-kidney-disease-from-the-old-to-the-new
#10
REVIEW
Ronald M Goldenberg, Murray Berall, Christopher T M Chan, David Z I Cherney, Julie A Lovshin, Philip A McFarlane, Peter A Senior, Subodh Verma, Jordan J Weinstein
Diabetic kidney disease (DKD) is a group of chronic kidney diseases that is associated with significant cardiovascular as well as all-cause morbidity and mortality. Although DKD is often progressive in nature, its evolution can be modified by intensive management of glycemia and blood pressure and inhibition of the renin-angiotensin-aldosterone system. This review provides an overview of how multifactorial interventions can provide renal protection and includes a discussion of the nonglycemic effects of incretin-based diabetes therapies (glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase 4 inhibitors) and sodium-glucose cotransporter-2 inhibitors within the kidney in patients with type 2 diabetes...
August 16, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28821421/exploring-canadian-physicians-experiences-with-diabetes-care-for-indigenous-patients
#11
Lynden Lindsay Crowshoe, Rita I Henderson, Michael E Green, Kristen M Jacklin, Leah M Walker, Betty Calam
OBJECTIVES: The perspectives of physicians caring for Indigenous patients with diabetes offer important insights into the provision of health-care services. The purpose of this study was to describe Canadian physicians' perspectives on diabetes care of Indigenous patients, a preliminary step in developing a continuing medical education intervention described elsewhere. METHODS: Through in-depth semistructured interviews, Canadian family physicians and specialists with sizeable proportions of Indigenous clientele shared their experiences of working with Indigenous patients who have type 2 diabetes...
August 15, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28821420/hyperglycemia-in-young-adults-seen-in-the-emergency-department-a-health-records-review
#12
Justin W Yan, Alexandra L Hamelin, Katherine M Gushulak, Kristine Van Aarsen, Melanie P Columbus, Ian G Stiell
Patients with diabetes who are in emerging adulthood, defined as the life stage between 18 and 29 years of age, have unique challenges in managing their illness and are at risk for acute complications and loss to follow up. This study's objective was to describe emergency department (ED) utilization because of hyperglycemia in emerging adults with diabetes and to characterize 30-day outcomes, including return visits and admission for hyperglycemia. This was a health-records review of emerging adults presenting over a 1-year period to 4 tertiary care EDs; the patients had known histories of diabetes and final diagnoses of hyperglycemia, diabetic ketoacidosis or hyperosmolar hyperglycemia...
August 15, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28803822/egg-consumption-and-cardiovascular-risk
#13
LETTER
J David Spence
No abstract text is available yet for this article.
August 10, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28803821/regarding-insulin-initiation-in-type-2-diabetes-mellitus-and-the-risk-for-hypoglycemia
#14
LETTER
Jan Brož, Brian M Frier
No abstract text is available yet for this article.
August 10, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28803820/titration-a-randomized-study-to-assess-2-treatment-algorithms-with-new-insulin-glargine-300-units-ml
#15
Jean-François Yale, Lori Berard, Mélanie Groleau, Pasha Javadi, John Stewart, Stewart B Harris
OBJECTIVE: It was uncertain whether an algorithm that involves increasing insulin dosages by 1 unit/day may cause more hypoglycemia with the longer-acting insulin glargine 300 units/mL (GLA-300). The objective of this study was to compare safety and efficacy of 2 titration algorithms, INSIGHT and EDITION, for GLA-300 in people with uncontrolled type 2 diabetes mellitus, mainly in a primary care setting. METHODS: This was a 12-week, open-label, randomized, multicentre pilot study...
August 10, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28800932/is-type-2-diabetes-associated-with-impaired-capacity-for-weight-loss
#16
Ghadi Antoun, Majid Nikpay, Ruth McPherson, Mary-Ellen Harper, Robert Dent
No abstract text is available yet for this article.
August 8, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28797890/developing-and-implementing-a-food-insecurity-screening-initiative-for-patients-living-with-diabetes
#17
Brittany Thomas, Sandra Fitzpatrick, Souraya Sidani, Enza Gucciardi
OBJECTIVES: Routine food insecurity screening is recommended in diabetes care to inform more tailored interventions that better support diabetes self-management among food-insecure patients. This pilot study explored the acceptability and feasibility of a food insecurity screening initiative within a diabetes care setting in Toronto. METHODS: A systematic literature review informed the development of a food insecurity screening initiative to help health-care providers tailor diabetes management plans and better support food-insecure patients with type 2 diabetes...
August 7, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28797889/insights-into-the-recognition-and-management-of-sglt2-inhibitor-associated-ketoacidosis-it-s-not-just-euglycemic-diabetic-ketoacidosis
#18
Stephanie Dizon, Erin J Keely, Janine Malcolm, Amel Arnaout
No abstract text is available yet for this article.
August 7, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28757254/framing-obesity-as-a-health-issue-differences-in-public-and-professional-perceptions-between-canada-and-the-united-states
#19
Bonnie L Kuehl, Sara F L Kirk, Nathalie Dumas, Theodore K Kyle
No abstract text is available yet for this article.
July 28, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28754435/children-with-type-1-diabetes-have-delayed-flow-mediated-dilation
#20
Sarveshinee Pillay, Jemma Anderson, Jennifer Couper, Oana Maftei, Roger Gent, Alexia Sophie Peña
OBJECTIVES: Children with type 1 diabetes have accelerated atherosclerosis with early endothelial dysfunction as measured by reduced flow-mediated dilation (FMD) at 60 seconds postischemic stress (early FMD). Delayed dilation may also occur in the presence of cardiovascular risk factors and may be a more sensitive marker. No data exist that evaluate FMD beyond 60 seconds (delayed FMD) in children with type 1 diabetes. We aimed to compare early and delayed FMD in children with type 1 diabetes and in healthy children...
July 25, 2017: Canadian Journal of Diabetes
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