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Canadian Journal of Diabetes

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https://www.readbyqxmd.com/read/28528246/the-canadian-hypoglycemia-assessment-tool-program-insights-into-rates-and-implications-of-hypoglycemia-from-an-observational-study
#1
Ronnie Aronson, Ronald Goldenberg, Damir Boras, Rasmus Skovgaard, Harpreet Bajaj
OBJECTIVE: The true prevalence of hypoglycemia in insulin-treated patients with diabetes and its impact on patients, employers and healthcare providers is poorly appreciated owing to a paucity of real-world data. The global Hypoglycemia Assessment Tool (HAT) study addressed this issue, and here we report data from the Canadian cohort of patients. METHODS: This noninterventional, 6-month retrospective and 4-week prospective study enrolled patients aged ≥18 years receiving insulin treatment for >12 months from community endocrinology practices...
May 17, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28506815/postpartum-diabetes-testing-rates-after-gestational-diabetes-mellitus-in-canadian-women-a-population-based-study
#2
Sonia Butalia, Lois Donovan, Anamaria Savu, Jeffrey Johnson, Alun Edwards, Padma Kaul
OBJECTIVES: We assessed the rate and type of postpartum glycemic testing in women with impaired glucose tolerance of pregnancy (IGTp) and gestational diabetes mellitus (GDM). We examined whether the likelihood of testing was modulated by patients' characteristics and pregnancy outcomes. METHODS: Our population-level cohort study included data from 132,905 pregnancies between October 1, 2008, and December 31, 2011, in Alberta, Canada. Laboratory data within 270 days before and 1 year after delivery were used to identify pregnancies involving IGTp/GDM and postpartum glycemic testing, respectively...
May 12, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28506814/the-relationship-between-type-2-diabetes-and-breast-cancer-incidence-in-differing-ethnic-groups
#3
REVIEW
Gertraud Maskarinec, Angelique Fontaine, Johanna Eyrun Torfadottir, Lorraine L Lipscombe, Iliana C Lega, Jonine Figueroa, Sarah Wild
In addition to rising type 2 diabetes and breast cancer incidence rates worldwide, diabetes may also increase breast cancer risk, and the association may vary by ethnicity. This review summarizes published data evaluating the association between diabetes and breast cancer in women of Asian, Hispanic and African American ancestry while considering a measure of obesity, body mass index (BMI). Published reports were identified through a search of PubMed and previous publications. Of 15 age-adjusted studies, 11 reported on Asian women from various countries, 3 on Hispanics and 1 on African Americans...
May 12, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28506813/the-effects-of-natural-clinoptilolite-and-nano-sized-clinoptilolite-supplementation-on-glucose-levels-and-oxidative-stress-in-rats-with-streptozotocin-induced-diabetes
#4
Behnoosh Hossein Nia, Sirous Khorram, Hassan Rezazadeh, Abdolrasol Safaiyan, Ali Tarighat-Esfanjani
OBJECTIVE: Oxidative stress has a major role in development of diabetic complications. In this study we investigated whether clinoptilolite and nano-sized clinoptilolite could reduce hyperglycemia and oxidative stress in streptozotocin-induced diabetic rats and attempted to determine which intervention was more effective. METHODS: Thirty-six rats were randomly allocated to 2 groups; 1 group was randomly chosen as a diabetic group and injected with streptozotocin (60 mg/kg body weight in 0...
May 12, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28499789/association-between-the-polymorphism-of-glu298asp-in-exon-7-of-the-enos-gene-with-foot-ulcer-and-oxidative-stress-in-patients-with-type-2-diabetes
#5
Seyedeh Maryam Sadati, Mania Radfar, Armita Kakavand Hamidi, Mohammad Abdollahi, Mostafa Qorbani, Ensieh Nasli Esfahani, Mahsa M Amoli
OBJECTIVES: Diabetic foot ulcer (DFU) is a common and major manifestation in patients with diabetes. Oxidative stress (OS) plays an important role in diabetic complications, such as DFU. Nitric oxide deficiency contributes to the impairment of diabetic wound healing. The aim of this study was to examine the association between the eNOS Glu298Asp polymorphism and DFU and oxidative stress in patients with type 2 diabetes mellitus in an Iranian population. METHODS: In this case-control study, 123 patients with type 2 diabetes and DFU and 134 patients without DFU were recruited...
May 10, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28499790/self-monitoring-blood-glucose-test-strip-utilization-in-saskatchewan-a-retrospective-study
#6
Lynette Kosar, Wasem Alsabbagh, Xinya Lu, Lisa M Lix, Yvonne Shevchuk, Gary F Teare, Anne Champagne, David F Blackburn
OBJECTIVES: To describe trends in blood glucose test strip (TS) utilization and cost in Saskatchewan. METHODS: A retrospective analysis of TS use between January 1, 1996, and December 31, 2013, was conducted using population-based health administrative databases in Saskatchewan. The prescription drug database was used to describe the annual number of TS dispensations, the number of strips dispensed, the number of unique beneficiaries and the total costs. A patient-level analysis was also carried out to describe the patterns of TS use (i...
May 9, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28499788/nocturia-and-prevalence-of-depressive-symptoms-in-japanese-patients-with-type-2-diabetes-mellitus-the-dogo-study
#7
Shinya Furukawa, Takenori Sakai, Tetsuji Niiya, Hiroaki Miyaoka, Teruki Miyake, Shin Yamamoto, Sayaka Kanzaki, Koutatsu Maruyama, Keiko Tanaka, Teruhisa Ueda, Hidenori Senba, Masamoto Torisu, Hisaka Minami, Takeshi Tanigawa, Bunzo Matsuura, Yoichi Hiasa, Yoshihiro Miyake
OBJECTIVES: No studies have investigated the association between nocturia and depressive symptoms in patients with type 2 diabetes mellitus. Because nocturia and depressive symptoms are common in patients with type 2 diabetes, we examined this association in Japanese patients with type 2 diabetes. METHODS: We studied 762 Japanese patients with type 2 diabetes. A self-administered questionnaire was used to collect information about the variables under study. The subjects were divided into 3 groups according to their nocturnal micturition: 1) no nocturia; 2) mild nocturia (1 void per night) and 3) moderate to severe nocturia (2 or more voids per night)...
May 9, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28478956/the-relationship-between-25-hydroxyvitamin-d-levels-insulin-sensitivity-and-insulin-secretion-in-women-3-years-after-delivery
#8
Tímea Tänczer, Rita Magenheim, Ágnes Fürst, Beatrix Domján, Zsófia Janicsek, Eszter Szabó, Viktória Ferencz, Ádám G Tabák
OBJECTIVES: There is a direct correlation between 25-hydroxyvitamin D (25[OH]D) levels and insulin sensitivity. Furthermore, women with gestational diabetes (GDM) may have lower levels of 25(OH)D compared to controls. The present study intended to investigate 25(OH)D levels and their association with insulin sensitivity and insulin secretion in women with prior GDM and in controls 3.2 years after delivery. METHODS: A total of 87 patients with prior GDM and 45 randomly selected controls (age range, 22 to 44 years) with normal glucose tolerance during pregnancy nested within a cohort of all deliveries at Saint Margit Hospital, Budapest, between January 1 2005, and December 31 2006, were examined...
May 3, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28476541/a-qualitative-study-of-young-adult-experiences-in-the-bariatric-healthcare-system-psychosocial-challenges-and-developmental-difficulties
#9
Marlene Taube-Schiff, Shira Yufe, Patti Kastanias, Mary Weiland, Sanjeev Sockalingam
OBJECTIVES: Bariatric surgery is an evidence-based treatment for severe obesity; however, the unique developmental and psychosocial needs of young adults often complicate care and, as yet, are not well understood. We sought to identify themes in young adult patients undergoing bariatric surgery regarding: 1) the psychosocial experiences of obese young adults (18 to 24) seeking bariatric surgery; 2) the experiences during the preoperative bariatric surgery process and 3) the postoperative experiences of young adult patients...
May 2, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28457649/diabetes-after-bariatric-surgery
#10
REVIEW
Ankit Shah, Blandine Laferrère
Bariatric surgery has now emerged as an effective means of glycemic control in individuals with diabetes and obesity. However, long-term data show recurrence of hyperglycemia years after the procedure. Although the exact prevalence of diabetes relapse is unknown because of attrition and limited data on long-term follow up after the surgery, a significant percentage of patients experience relapse of diabetes. The mechanism of diabetes relapse is not completely understood and is not always linked to weight regain...
April 27, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28454899/population-level-outcomes-with-a-2-step-approach-for-gestational-diabetes-screening-and-diagnosis
#11
L E Donovan, A L Edwards, A Savu, S Butalia, E A Ryan, J A Johnson, P Kaul
OBJECTIVES: To examine outcomes associated with alternative glucose thresholds in a 2-step approach for screening and diagnosing gestational diabetes mellitus (GDM). METHODS: We studied 178,527 pregnancies between 2008 and 2012 in Alberta, Canada. They were categorized retrospectively as normal 50 g screen (n=144,191); normal 75 g oral glucose tolerance test (OGTT) (n=21,248); abnormal at glucose thresholds suggested by the International Association of Diabetes and Pregnancy Group (IADPSG) (HAPO 1...
April 25, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28462795/diabetes-distress-depression-and-glycemic-control-in-a-canadian-based-specialty-care-setting
#12
Evelyn M Wong, Rowshanak Afshar, Hong Qian, Mira Zhang, Thomas G Elliott, Tricia S Tang
OBJECTIVES: The objectives of this study were to determine rates of diabetes distress and depression in patients with type 2 diabetes in a tertiary care setting, to examine the relationship among glycemic control, diabetes distress and depression, and to identify predictors of diabetes distress and depression on the basis of demographic and clinical characteristics. METHODS: We recruited 148 adults with type 2 diabetes who were presenting to a specialty diabetes clinic in Vancouver, British Columbia, Canada...
April 24, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28433264/practical-tips-for-insulin-use-in-primary-care
#13
Jacqueline Smith
No abstract text is available yet for this article.
April 19, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28416367/serum-galanin-concentration-is-increased-in-subjects-with-impaired-glucose-tolerance
#14
Zhenwen Zhang, Penghua Fang, Mei Yu, Yan Wang, Yin Li, Mingyi Shi, Ping Bo, Xuewen Gu, Yan Zhu
OBJECTIVES: Although extensive data have shown that galanin can regulate the food intake and glucose metabolism of animals, little is known regarding the galanin concentration in patients with impaired glucose tolerance (IGT). Therefore, the aims of this study were to investigate whether serum galanin levels and other metabolic parameters are changed in patients with IGT compared with controls with normal glucose tolerance (NGT). METHODS: Data regarding serum galanin levels and relative metabolic parameters were collected in 12 patients with IGT and 12 healthy patients with NGT...
April 14, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28410881/patterns-policy-and-appropriateness-a-12-year-utilization-review-of-blood-glucose-test-strip-use-in-insulin-users
#15
Jamie Falk, Kevin J Friesen, Anuoluwapo Okunnu, Shawn Bugden
OBJECTIVES: Considerable attention has been paid to the rising costs of the use of blood glucose test strips (BGTS). Insulin users have generally been treated as a single homogeneous group, resulting in policies that cap usage (8.2 strips/day) in provincial drug insurance programs. The objective of this study was to conduct a utilization review of BGTS by insulin users and to evaluate use patterns against current insulin use patterns and BGTS policy. METHODS: BGTS usage was examined in a cohort of insulin users with type 1 and type 2 diabetes over a 12-year period (2001 to 2013) using the population-based administrative data in Manitoba, Canada...
April 11, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28392300/glucagon-like-peptide-1-receptor-agonists-a-class-update-for-treating-type-2-diabetes
#16
REVIEW
Julie A Lovshin
Current management options for treating type 2 diabetes are diverse. Many different classes of antidiabetes therapies are used in clinic, and several new candidates are in late-phase clinical trial. This therapeutic abundance is a windfall for patients because it facilitates individualized patient care. Evidence-based positioning of these agents is challenging, however, requiring comprehensive and balanced familiarity with each drug class. In this review, I provide a clinical update of glucagon-like peptide-1 receptor agonists (GLP-1RAs), a class of incretin-based, injectable antidiabetes therapies which improve fasting and postprandial blood glucose control through glucose-dependent pancreatic islet cell hormone secretion without significant risks for hypoglycemia...
April 5, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28392023/building-competency-and-capacity-for-promotion-of-effective-physical-activity-in-diabetes-care-in-canada
#17
Emily Gray, Christopher Shields, Jonathon R Fowles
OBJECTIVES: The purpose of the present study was to examine the impact of the Canadian Diabetes Association's (CDA) resource titled Building Competency in Diabetes Education: Physical Activity and Exercise and associated workshops, on diabetes care providers' (DCPs) confidence and practices regarding physical-activity promotion 8 to 12 months after attending a workshop. METHODS: In this action research study, 2 separate cross-sectional samples of DCPs were recruited...
April 5, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28373033/the-influence-of-proton-pump-inhibitors-on-glycemic-control-a-systematic-review-of-the-literature-and-a-meta-analysis
#18
Juan C Gómez-Izquierdo, Oriana Hoi Yun Yu
OBJECTIVES: Proton-pump inhibitors (PPIs) have shown antihyperglycemic effects by stimulating insulin secretion. The aim of this study was to analyze the effect of PPIs on glucose metabolism in general and any potential antidiabetes effects in patients with type 2 diabetes. METHODS: A systematic search was conducted in MEDLINE, Embase, Cochrane and PubMed. Studies using PPIs as interventions and reporting glucose levels, glycated hemoglobin (A1C) levels and insulin levels were selected...
March 31, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28366674/effects-of-high-intensity-interval-training-on-people-living-with-type-2-diabetes-a-narrative-review
#19
REVIEW
Shohn G Wormgoor, Lance C Dalleck, Caryn Zinn, Nigel K Harris
People with type 2 diabetes typically present with comorbidities, such as elevated blood pressure, high cholesterol, high blood glucose, obesity and decreased fitness, all contributive to increased risk for cardiovascular complications. Determination of effective exercise modalities for the management of such complications is important. One such modality is high-intensity interval training (HIIT). To conduct the review, PubMed and EBSCOHost databases were searched through June 1, 2016, for all HIIT intervention studies conducted in people living with type 2 diabetes...
March 30, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28366673/ketonemia-promoted-by-an-sglt2-inhibitor-in-a-patient-with-hyperthyroidism
#20
Masanori Shimodaira, Sadao Nakajima
No abstract text is available yet for this article.
March 30, 2017: Canadian Journal of Diabetes
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