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Canadian Journal of Diabetes

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https://www.readbyqxmd.com/read/29129456/a-canadian-cross-sectional-survey-on-psychosocial-supports-for-people-living-type-1-or-2-diabetes-health-care-providers-awareness-capacity-and-motivation
#1
Jennica Nichols, Michael Vallis, Stephanie Boutette, Carolyn Gall Casey, Catherine H Yu
OBJECTIVES: Addressing psychosocial issues is critical for diabetes self-management. This work explores health-care professionals' (HCPs') 1) perceived relevance of various psychosocial issues in diabetes management and 2) confidence in working on these issues within their services. METHODS: An online cross-sectional survey was developed based on the Capacity-Opportunity-Motivation Behaviour Model. It assessed self-rated confidence in supporting patients with psychosocial issues (capability), perceived relevance of these issues (motivation) and facilitators of skill development (opportunity)...
November 9, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29129455/plasma-palmitoyl-carnitine-ac16-0-is-a-marker-of-increased-postprandial-nonesterified-incomplete-fatty-acid-oxidation-rate-in-individuals-with-type-2-diabetes
#2
Fatima-Zahra Bouchouirab, Mélanie Fortin, Christophe Noll, Jean Dubé, André C Carpentier
OBJECTIVES: Enhanced mitochondrial fatty acid utilization is known to increase radical oxidative stress and induce insulin resistance. An increased level of plasma acylcarnitine (AC) has been proposed to indicate mitochondrial energy substrate overload, a possible mechanism leading to insulin resistance. The aim of our study was to determine fasting and postprandial plasma acetyl-carnitine (AC2:0), palmitoyl-carnitine (AC16:0), oleoyl-carnitine (AC18:1) and linoleoyl-carnitine (AC18:2) levels and their relationships with plasma nonesterified fatty acid appearance and oxidation rates and insulin sensitivity in participants with type 2 diabetes and normoglycemic offspring of 2 parents with type 2 diabetes (FH+) compared to healthy participants without family histories of type 2 diabetes (FH-)...
November 9, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29128304/symptoms-of-mental-illness-and-their-impact-on-managing-type-2-diabetes-in-adults
#3
Adriana Cimo, Carolyn S Dewa
OBJECTIVES: People with mental illnesses are more likely to experience diabetes-related complications that can reduce life expectancy by 10 to 15 years. Diabetes management and outcomes can be improved when lifestyle interventions addressing healthful eating habits and physical activity use content tailored to the learning needs of individuals or groups. Understanding the challenges that prevent adherence to diabetes recommendations can start to inform the design of tailored diabetes education care...
November 8, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29128303/the-mountain-of-health-the-perceptions-and-perceived-expectations-of-youth-living-with-type-2-diabetes-in-winnipeg-manitoba-canada-through-a-grounded-theory-study
#4
Elizabeth Huynh
OBJECTIVE: The objective of this study was to explore youth's perceptions of diabetes management. METHODS: The study included 8 Manitoban youth with type 2 diabetes (n=7 girls). Each youth participated in a semistructured interview in person, via Skype or over the phone. The constructivist grounded theory methodologic approach guided the analysis of the data. RESULTS: Discussions about diabetes and health and its management revealed 2 viewpoints: 1) youth's perceptions and 2) youth's perceptions of health-care providers' expectations...
November 8, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29103904/effects-of-diabetes-mellitus-on-cognitive-decline-in-patients-with-alzheimer-disease
#5
LETTER
Tomoyuki Kawada
No abstract text is available yet for this article.
November 3, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29056257/eating-behaviours-and-prevalence-of-gastroesophageal-reflux-disease-in-japanese-patients-with-type-2-diabetes-mellitus-the-dogo-study
#6
Eiji Takeshita, Shinya Furukawa, Takenori Sakai, Tetsuji Niiya, Hiroaki Miyaoka, Teruki Miyake, Shin Yamamoto, Hidenori Senba, Yasunori Yamamoto, Eiji Arimitsu, Sen Yagi, Hiroki Utsunomiya, Keiko Tanaka, Yoshio Ikeda, Bunzo Matsuura, Yoshihiro Miyake, Yoichi Hiasa
OBJECTIVES: In the general population, late-night dinner is positively associated with gastroesophageal reflux disease (GERD). No evidence exists regarding the relationship between eating behaviours and GERD in patients with type 2 diabetes mellitus, though the prevalence of GERD in patients with type 2 diabetes is higher than in those without diabetes. We conducted this study to investigate the association between eating behaviours and GERD in Japanese patients with type 2 diabetes. METHODS: The study's subjects were 817 Japanese patients with type 2 diabetes...
October 19, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29037573/pharmacists-scope-of-practice-supports-for-canadians-with-diabetes
#7
Kerry Mansell, Kirsten Edmunds, Lisa Guirguis
OBJECTIVES: The pharmacists' role in Canada has significantly advanced over the past decade, resulting in increasing access to primary care services. This study aimed to characterize pharmacists' expanded scope of practice as it relates to providing services to Canadians with diabetes. METHODS: This environmental scan characterized services that could be useful to Canadians with diabetes in each of the provinces (excluding the territories): immunizations, medication prescribing, ordering and interpreting laboratory tests, and medication reviews...
October 13, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29037572/gender-related-differences-in-the-control-of-cardiovascular-risk-factors-in-primary-care-for-elderly-patients-with-type-2-diabetes-a-cohort-study
#8
Abdallah Al-Salameh, Sophie Bucher, Bernard Bauduceau, Linda Benattar-Zibi, Gilles Berrut, Philippe Bertin, Emmanuelle Corruble, Nicolas Danchin, Geneviève Derumeaux, Jean Doucet, Bruno Falissard, Françoise Forette, Olivier Hanon, Rissane Ourabah, Florence Pasquier, Michel Pinget, Virginie Ringa, Laurent Becquemont
OBJECTIVE: The aim of this study was to estimate the association between gender and control of diabetes and other cardiovascular risk factors in elderly patients with type 2 diabetes mellitus. METHODS: The sujets âgés cohort is an observational study whose main objective was to describe the real-life management of elderly patients with type 2 diabetes mellitus in France. Nine hundred eighty-three patients with diabetes (517 men and 466 women) were recruited by 213 general practitioners and were followed up prospectively every 6 months for 3 years...
October 13, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29037571/effect-of-ruta-chalepensis-on-zinc-lipid-profile-and-antioxidant-levels-in-the-blood-and-tissue-of-streptozotocin-induced-diabetes-in-rats-fed-zinc-deficient-diets
#9
Malika Hamdiken, Samira Bouhalit, Zine Kechrid
In diabetes, oxidative stress and lipid abnormalities are common and pronounced and represent important factors that are involved in the development of complications of diabetes. Zinc deficiency generally induces oxidative stress, but it is well known that the antioxidant Ruta chalepensis has an effective modulator role in oxidative stress in metabolic diseases. The aim of this study was to investigate the effect of R. chalepensis extract on blood biochemical parameters, tissue zinc status and antioxidant systems in rats with diabetes that were fed zinc-deficient diets...
October 13, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28965748/the-effectiveness-of-pharmacist-interventions-on-cardiovascular-risk-in-adult-patients-with-type-2-diabetes-the-multicentre-randomized-controlled-rxeach-trial
#10
Yazid N Al Hamarneh, Brenda R Hemmelgarn, Imran Hassan, Charlotte A Jones, Ross T Tsuyuki
Cardiovascular disease (CVD) is the leading cause of death among patients with diabetes. Management and control of CV risk factors in those with diabetes are generally poor. Pharmacists are frontline primary healthcare providers who see patients with chronic diseases frequently. As such, they are in a prime position to systematically identify patients with diabetes, assess their CV risk and assist in their disease management and preventive measures. OBJECTIVE: to evaluate the effect of pharmacist case finding and intervention program on estimated CV risk in patients with diabetes...
September 28, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28958785/cognitive-impairment-mediates-workplace-impairment-in-persons-with-type-2-diabetes-mellitus-results-from-the-motivaction-study
#11
Yena Lee, Allan Smofsky, Priscilla Nykoliation, Stephen Allain, Linda Lewis-Daly, Jeremy Schwartz, Joshua Hart Pollack, Jean-Eric Tarride, Roger S McIntyre
OBJECTIVES: Type 2 diabetes mellitus (DM) is associated with substantial impairments in workplace function; however, the mediators of workplace performance in DM are not well characterized. Herein, we investigate depressive symptomatology and cognitive dysfunction as mediators of workplace productivity and hypothesize that workplace impairment is mediated principally by cognitive dysfunction in DM. METHODS: The Motivaction study screened individuals employed across Canada for diabetes...
September 25, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28958689/top-10-things-pharmacists-should-consider-when-they-interact-with-patients-with-type-2-diabetes
#12
Yazid N Al Hamarneh, Rick L Siemens, Kendra J Townsend
No abstract text is available yet for this article.
September 22, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28943221/development-of-perinatal-mental-illness-in-women-with-gestational-diabetes-mellitus-a-population-based-cohort-study
#13
Qendresa Beka, Samantha Bowker, Anamaria Savu, Dawn Kingston, Jeffrey A Johnson, Padma Kaul
OBJECTIVES: To examine the relationship between gestational diabetes mellitus (GDM) and the development of mental illness (affective and anxiety disorders) during pregnancy and 1 year postpartum. METHODS: We linked clinical and administrative databases of mothers who delivered in Alberta, Canada, between April 1, 2000, and March 31, 2009, to identify diagnoses of GDM and mental illness. Women with prepregnancy type 1 or type 2 diabetes were excluded. We used generalized estimating equation models to examine the effect of GDM on the development of new-onset mental illness in 2 separate periods: during pregnancy and during the first postpartum year...
September 22, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28935357/pharmacists-managing-people-with-diabetes-in-primary-care-10-years-of-experience-at-the-hamilton-family-health-team
#14
Antony Gagnon, Margaret Jin, Mark Malak, Katalin Bednarowski, Lucy Feng, Sophia Francis-Pringle, Sandy Lu, Anne Mallin, Dragana Skokovic-Sunjic, Annette Vedelago
No abstract text is available yet for this article.
September 18, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28942790/glucagon-like-peptide-1-receptor-agonists-a-class-update-for-treating-type-2-diabetes
#15
REVIEW
Julie A Lovshin
Current management options for treating type 2 diabetes are diverse. Many different classes of antidiabetes therapies are used in clinic, and several new candidates are in late-phase clinical trial. This therapeutic abundance is a windfall for patients because it facilitates individualized patient care. Evidence-based positioning of these agents is challenging, however, requiring comprehensive and balanced familiarity with each drug class. In this review, I provide a clinical update of glucagon-like peptide-1 receptor agonists (GLP-1RAs), a class of incretin-based, injectable antidiabetes therapies which improve fasting and postprandial blood glucose control through glucose-dependent pancreatic islet cell hormone secretion without significant risks for hypoglycemia...
October 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28942789/the-role-of-sodium-glucose-cotransporter-2-inhibitors-in-the-management-of-type-2-diabetes
#16
REVIEW
Oren Steen, Ronald M Goldenberg
Sodium-glucose cotransporter 2 (SGTL2) inhibitors are a novel class of antihyperglycemic agents that work in an insulin-independent manner by promoting urinary glucose excretion. In addition to efficacious glucose lowering, they exert beneficial effects on blood pressure and weight while avoiding hypoglycemia unless combined with insulin or insulin secretagogues. This review explores the mechanism of action of SGLT2 inhibitors, their effects on glycated hemoglobin, weight, blood pressure and hypoglycemia, potential adverse effects, renal considerations and cardiovascular outcomes...
October 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28942788/insulin-management-strategies-for-exercise-in-diabetes
#17
REVIEW
Dessi P Zaharieva, Michael C Riddell
There is no question that regular exercise can be beneficial and lead to improvements in overall cardiovascular health. However, for patients with diabetes, exercise can also lead to challenges in maintaining blood glucose balance, particularly if patients are prescribed insulin or certain oral hypoglycemic agents. Hypoglycemia is the most common adverse event associated with exercise and insulin therapy, and the fear of hypoglycemia is also the greatest barrier to exercise for many patients. With the appropriate insulin dose adjustments and, in some cases, carbohydrate supplementation, blood glucose levels can be better managed during exercise and in recovery...
October 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28942787/toddlers-with-type-1-diabetes-in-daycare-issues-with-administering-insulin-lessen-options
#18
Julie Halipchuk, Lindsay Sawatsky
No abstract text is available yet for this article.
October 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28942786/canadian-journal-of-diabetes-welcomes-a-new-editor-in-chief
#19
EDITORIAL
David C W Lau
No abstract text is available yet for this article.
October 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28863979/computer-simulation-model-to-train-medical-personnel-on-glucose-clamp-procedures
#20
Pooya Maghoul, Benoit Boulet, Annie Tardif, Ahmad Haidar
OBJECTIVE: A glucose clamp procedure is the most reliable way to quantify insulin pharmacokinetics and pharmacodynamics, but skilled and trained research personnel are required to frequently adjust the glucose infusion rate. A computer environment that simulates glucose clamp experiments can be used for efficient personnel training and development and testing of algorithms for automated glucose clamps. METHODS: We built 17 virtual healthy subjects (mean age, 25±6 years; mean body mass index, 22...
October 2017: Canadian Journal of Diabetes
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