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Canadian Journal of Diabetes

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https://www.readbyqxmd.com/read/27916497/the-diabeates-project-perceptual-affective-and-psychophysiological-effects-of-music-and-music-video-in-a-clinical-exercise-setting
#1
Jasmin C Hutchinson, Costas I Karageorghis, Jessica D Black
OBJECTIVES: The purpose of this study was to examine the effects of music and music-video on perceptual (attentional focus, rated perceived exertion), affective (affective valence and enjoyment) and psychophysiological (blood glucose, heart rate) variables in outpatients attending a diabetes exercise clinic. METHODS: Participants were 24 females (age = 66.0 ± 8.5 years) enrolled in a supervised exercise program for people with diabetes. They engaged in mixed-modality exercise sessions that included a standardized combination of flexibility, aerobic and resistance activities under conditions of music, music-video and control...
December 1, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27916496/hyperlipidemia-mediated-increased-advanced-lipoxidation-end-products-formation-an-important-factor-associated-with-decreased-erythrocyte-glucose-6-phosphate-dehydrogenase-activity-in-mild-nonproliferative-diabetic-retinopathy
#2
Subhadip Choudhuri, Pijush Kanti Roy, Bhaskar Mitra, Susruta Sen, Rajarshi Sarkar, Mandrita Das, Debashree Biswas, Prithwijit Ghosh, Ajoy Biswas, Shaibal Chakraborty, Lakshmi Kanta Mondal
OBJECTIVES: The present study aimed to evaluate the role of hyperlipidemia in increased formation of advanced lipoxidation end products (ALEs) and to evaluate whether there is any relationship between ALEs generation and erythrocyte glucose-6-phosphate dehydrogenase (G6PD) activity in cases of mild nonproliferative diabetic retinopathy (MNPDR). METHODS: In this study, we enrolled 100 patients with type 2 diabetes and MNPDR, 100 subjects with type 2 diabetes but without retinopathy (DNR) and 90 normal individuals without diabetes as healthy controls (HCs)...
December 1, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27913110/downregulated-brain-derived-neurotrophic-factor-induced-oxidative-stress-in-the-pathophysiology-of-diabetic-retinopathy
#3
REVIEW
Tapan Behl, Anita Kotwani
Brain-derived neurotrophic factor (BDNF), a member of neurotrophin growth factor family, physiologically mediates induction of neurogenesis and neuronal differentiation, promotes neuronal growth and survival and maintains synaptic plasticity and neuronal interconnections. Unlike the central nervous system, its secretion in the peripheral nervous system occurs in an activity-dependent manner. BDNF improves neuronal mortality, growth, differentiation and maintenance. It also provides neuroprotection against several noxious stimuli, thereby preventing neuronal damage during pathologic conditions...
November 29, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27908559/influence-of-a-pay-for-performance-program-on-glycemic-control-in-patients-living-with-diabetes-by-family-physicians-in-a-canadian-province
#4
Emilie LeBlanc, Mathieu Bélanger, Véronique Thibault, Lise Babin, Beverly Greene, Stuart Halpine, Michelina Mancuso
OBJECTIVES: We evaluated the influence of the introduction of a pay-for-performance program implemented in 2010 for family physicians on the glycemic control of patients with diabetes. METHODS: Administrative data for all 583 eligible family physicians and 83,580 adult patients with diabetes in New Brunswick over 10 years were used. We compared the probability of receiving at least 2 tests for glycated hemoglobin (A1C) levels and achieving glycemic control before (2005-2009) and after (2010-2014) the implementation of the program and between patients divided based on whether a physician claimed the incentive or did not...
November 29, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27908558/time-varying-risk-for-breast-cancer-following-initiation-of-glucose-lowering-therapy-in-women-with-type-2-diabetes-exploring-detection-bias
#5
Samantha L Bowker, Mu Lin, Dean T Eurich, Jeffrey A Johnson
OBJECTIVES: To explore detection bias in the association between glucose-lowering therapies and breast cancer in a cohort of women with type 2 diabetes. METHODS: This was a retrospective, population-based cohort study. We identified new users of metformin, sulfonylureas, thiazolidinediones and insulin during the index period of January 1, 2003, to December 31, 2010. The main outcome was incident breast cancer, and patients were followed up from drug exposure index date until death, diagnosis of another type of cancer, termination of medical insurance or December 31, 2010...
November 29, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27889175/inhibition-of-adenylyl-cyclase-in-the-spinal-cord-alleviates-painful-diabetic-neuropathy-in-zucker-diabetic-fatty-rats
#6
Hao Feng, Guodong Lu, Qingsong Li, Zhonghao Liu
OBJECTIVES: Diabetic neuropathy is the most common complication of both type 1 and type 2 diabetes. In this study, we tested the hypotheses that impaired Gi protein expression/function in the spinal cord is associated with the development of painful neuropathy in people with type 2 diabetes and that reduction of cyclic adenosine monophosphate (cAMP) production by inhibiting adenylyl cyclase in the spinal cord can alleviate diabetic neuropathy. METHODS: To this end, we examined the levels of cAMP, cAMP-dependent protein kinase (PKA) and cAMP response element-binding protein (CREB) in the spinal cord after the development of neuropathic pain in Zucker diabetic fatty (ZDF) rats with type 2 diabetes...
November 23, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27887926/geographic-clustering-of-acute-complications-and-sociodemographic-factors-in-adults-with-type-1-diabetes
#7
Sonia Butalia, Alka B Patel, Jeffrey A Johnson, William A Ghali, Doreen M Rabi
OBJECTIVES: To assess the geographic distribution of acute complications in patients with type 1 diabetes in a large urban centre; and to assess the association between acute complications and community-level sociodemographic factors. METHODS: Adults (aged ≥18 years old) with type 1 diabetes and acute complications were identified between 2004 and 2008 by using a diabetes centre clinical database or discharge abstracts for acute complications (diabetic ketoacidosis or hypoglycemia)...
November 23, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27884550/effects-of-changing-the-amount-and-source-of-dietary-carbohydrates-on-symptoms-and-dietary-satisfaction-over-a-1-year-period-in-subjects-with-type-2-diabetes-canadian-trial-of-carbohydrates-in-diabetes-ccd
#8
Thomas M S Wolever, Jean-Louis Chiasson, Robert G Josse, Lawrence A Leiter, Pierre Maheux, Rémi Rabasa-Lhoret, N Wilson Rodger, Edmond A Ryan
OBJECTIVES: To determine the long-term effects of changing the amount or source of dietary carbohydrate on quality of life (QOL), symptoms and dietary satisfaction in people with type 2 diabetes. METHODS: Subjects with diabetes treated by diet alone (n=162) were randomly assigned to high-carbohydrate/high-glycemic-index (HGI) diets; high-carbohydrate/low-glycemic-index (LGI) diets; or lower-carbohydrate/high-monounsaturated-fat (LC) diets for 1 year. We measured QOL at baseline and at study's end, and we measured symptoms and dietary satisfaction quarterly...
November 21, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27881298/engaging-patients-and-clinicians-in-establishing-research-priorities-for-gestational-diabetes-mellitus
#9
Sandra E Rees, Rati Chadha, Lois E Donovan, Adrienne L T Guitard, Sudha Koppula, Andreas Laupacis, Sara Simpson, Jeffrey A Johnson
OBJECTIVES: We involved patients and clinicians in Alberta, Canada, to establish research priorities in gestational diabetes mellitus (GDM), using an approach based on a model proposed by the James Lind Alliance (JLA). METHODS: We adapted the 4-step JLA process to engage women with GDM and clinicians to identify uncertainties about the management of GDM. Uncertainties were identified through a survey and a review of the clinical practice guidelines (CPG). Uncertainties were short-listed by a steering committee, followed by a 1-day facilitated workshop using a nominal group format and involving a similar number of patients and clinicians, who identified the top 10 research priorities...
November 21, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27881297/a-randomized-controlled-clinical-trial-investigating-the-effects-of-omega-3-fatty-acids-and-vitamin-e-co-supplementation-on-biomarkers-of-oxidative-stress-inflammation-and-pregnancy-outcomes-in-gestational-diabetes
#10
Mehri Jamilian, Shahrzad Hashemi Dizaji, Fereshteh Bahmani, Mohsen Taghizadeh, Mohammad Reza Memarzadeh, Maryam Karamali, Maryam Akbari, Zatollah Asemi
OBJECTIVES: Limited data are available for assessing the effects of omega-3 fatty acids and vitamin E co-supplementation on metabolic profiles and pregnancy outcomes in gestational diabetes (GDM). This study was designed to determine the effects of omega-3 fatty acids and vitamin E co-supplementation on biomarkers of oxidative stress, inflammation and pregnancy outcomes in women with GDM. METHODS: This randomized, double-blind, placebo-controlled clinical trial was conducted in 60 patients with GDM who were not taking oral hypoglycemic agents...
November 21, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27881296/is-new-onset-diabetes-after-kidney-transplantation-associated-with-autosomal-dominant-polycystic-kidney-disease-in-recipients-of-kidney-transplants-incomplete-methodologies-were-employed
#11
LETTER
Chao Zhang, Jun-Yi Wu, Zheng-Yan Gao
No abstract text is available yet for this article.
November 21, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27838228/can-the-combination-of-incretin-agents-and-sodium-glucose-cotransporter-2-sglt2-inhibitors-reconcile-the-yin-and-yang-of-glucagon
#12
Ronald M Goldenberg, Subodh Verma, Bruce A Perkins, Jeremy D Gilbert, Bernard Zinman
No abstract text is available yet for this article.
November 10, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27789111/the-relationship-between-diabetes-care-quality-and-diabetes-related-hospitalizations-and-the-modifying-role-of-comorbidity
#13
Yelena Petrosyan, Yu Qing Bai, Anna J Koné Pefoyo, Andrea Gruneir, Kednapa Thavorn, Colleen J Maxwell, Susan E Bronskill, Walter P Wodchis
OBJECTIVES: To evaluate the impact of comorbidity on diabetes care quality and diabetes-related hospitalizations and to examine whether associations between the likelihood of diabetes-related hospitalizations and compliance with diabetes testing are modified by type of comorbidity. METHODS: A population-based cohort study of 861 354 adults with diabetes was conducted in Ontario, Canada. The diabetes cohort was categorized into 4 groups defined by their comorbidity statuses: no comorbidity, diabetes-concordant only, diabetes-discordant only, and both concordant and discordant...
October 24, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27776891/mortality-and-cardiovascular-risk-of-sulfonylureas-in-south-asian-chinese-and-other-canadians-with-diabetes
#14
Calvin Ke, Steve Morgan, Kate Smolina, Danijela Gasevic, Hong Qian, Nadia Khan
OBJECTIVES: Sulfonylureas have been inconsistently associated with increased cardiovascular mortality in patients with type 2 diabetes mellitus. However, there are no existing studies of long-term risk in South Asian and Chinese populations. Our objective was to determine whether sulfonylureas are associated with increased mortality or cardiovascular disease in a population cohort of South Asian, Chinese and other Canadian patients with incident diabetes. METHODS: We studied a population-based cohort of adults 35 years of age or older who had diabetes and had been diagnosed between April 2004 and March 2014 by using administrative databases from British Columbia...
October 21, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27745846/diabetes-distress-and-depression-in-south-asian-canadians-with-type-2-diabetes
#15
Rawel Sidhu, Tricia S Tang
OBJECTIVES: South Asians are disproportionately affected by diabetes compared to some other ethnic groups in Canada. Although depression and diabetes distress are psychological issues well studied in the general population of those with diabetes, they have not been investigated in South Asian Canadians with type 2 diabetes. We sought to identify the rates of depression and diabetes distress in South Asian adults with type 2 diabetes and to explore the relationship among glycemic control, depression and diabetes distress...
October 10, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27727090/impact-of-the-balanced-school-day-on-glycemic-control-in-children-with-type-1-diabetes
#16
Robert I Stein, Manpreet Doulla, Jamie A Seabrook, Lorraine Yau, Natasha Hamilton, Marina I Salvadori, Paula D N Dworatzek
OBJECTIVE: The balanced school day (BSD) is an alternative elementary school schedule whereby children have 2 20-minute eating periods instead of 1 20-minute lunch, as is found in the traditional schedule (TS). We assessed the glycated hemoglobin (A1C) levels of children with type 1 diabetes in the TS vs. the BSD because 2 eating periods have the potential to impact blood glucose control. METHODS: A1C levels representative of the summer months (SumA1C) and A1C levels occurring at least 3 months after the start of the school year (SchA1C) were obtained retrospectively...
October 7, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27697449/a-longitudinal-investigation-of-anxiety-and-depressive-symptomatology-and-exercise-behaviour-among-adults-with-type-2-diabetes-mellitus
#17
Elena Ivanova, Rachel J Burns, Sonya S Deschênes, Bärbel Knäuper, Norbert Schmitz
OBJECTIVES: Evidence suggests that symptoms of depression and anxiety predict lower exercise behaviour and, inversely, that less exercise predicts higher symptomatology. The present longitudinal study examined this reciprocal association in adults with type 2 diabetes mellitus. We predicted that symptoms of anxiety or depression would intensify over time as a consequence of lower exercise frequency and, similarly, that exercise frequency would decrease as a consequence of greater symptoms of anxiety or depression...
September 30, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27692960/association-between-physical-activity-and-health-related-quality-of-life-in-adults-with-type-2-diabetes
#18
Danielle M Thiel, Fatima Al Sayah, Jeff K Vallance, Steven T Johnson, Jeffrey A Johnson
OBJECTIVES: To examine the association between meeting physical-activity recommendations and health-related quality of life (HRQL) in adults with type 2 diabetes. METHODS: Data from the Alberta's Caring for Diabetes cohort were used. Self-report questionnaires were mailed to patients with type 2 diabetes who were living in Alberta, Canada. Weekly moderate-vigorous physical activity (MVPA) was reported using the Godin Leisure Time Physical Activity Questionnaire, and HRQL was reported using the Medical Outcomes Study (MOS) 12-Item Short-Form Health Survey v...
September 28, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27658766/diabetes-in-emerging-adulthood-transitions-lost-in-translation
#19
Benjamin Markowitz, Janet A Parsons, Andrew Advani
No abstract text is available yet for this article.
September 19, 2016: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/27658765/the-effect-of-nurse-practitioner-led-intervention-in-diabetes-care-for-patients-admitted-to-cardiology-services
#20
Suqing Li, Sylvia Roschkov, Blair J O'Neill, Constance L Chik, Ross T Tsuyuki, Gabor T Gyenes
OBJECTIVE: To determine the benefits of diabetes nurse practitioner (DNP) intervention on glycemic control, quality of life and diabetes treatment satisfaction in patients with type 2 diabetes (T2DM) admitted to cardiology inpatient services at a tertiary center. PATIENTS AND METHODS: Patients admitted to the cardiology service with T2DM who had sub-optimal control (HbA1c >6.5%) were approached for the study. Diabetes care was optimized by the DNP through medication review, patient education and discharge care-planning...
September 19, 2016: Canadian Journal of Diabetes
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