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Environmental Health: a Global Access Science Source

Jeniffer S Kim, Tanya L Alderete, Zhanghua Chen, Fred Lurmann, Ed Rappaport, Rima Habre, Kiros Berhane, Frank D Gilliland
BACKGROUND: Evidence suggests that childhood near-roadway air pollution (NRAP) exposures contribute to increased body mass index (BMI); however, effects of NRAP exposure during the vulnerable periods including in utero and first year of life have yet to be established. In this study, we examined whether exposure to elevated concentrations of NRAP during in utero and/or first year of life increase childhood BMI growth. METHODS: Participants in the Children's Health Study enrolled from 2002 to 2003 with annual visits over a four-year period and who changed residences before study entry were included (n = 2318)...
September 14, 2018: Environmental Health: a Global Access Science Source
Nathalie Costet, Rémi Béranger, Ronan Garlantézec, Florence Rouget, Christine Monfort, Sylvaine Cordier, Fabienne Pelé, Cécile Chevrier
Following publication of the original article [1], the author asked to replace Table 2 with the correct version.
September 4, 2018: Environmental Health: a Global Access Science Source
Amy M Padula, Hongtai Huang, Rebecca J Baer, Laura M August, Marta M Jankowska, Laura L Jellife-Pawlowski, Marina Sirota, Tracey J Woodruff
BACKGROUND: Environmental pollution exposure during pregnancy has been identified as a risk factor for preterm birth. Most studies have evaluated exposures individually and in limited study populations. METHODS: We examined the associations between several environmental exposures, both individually and cumulatively, and risk of preterm birth in Fresno County, California. We also evaluated early (< 34 weeks) and spontaneous preterm birth. We used the Communities Environmental Health Screening Tool and linked hospital discharge records by census tract from 2009 to 2012...
August 29, 2018: Environmental Health: a Global Access Science Source
Jean Strelitz, Lawrence S Engel, Richard K Kwok, Aubrey K Miller, Aaron Blair, Dale P Sandler
BACKGROUND: Workers involved in the response and clean-up of the 2010 Deepwater Horizon oil spill faced possible exposures to crude oil, burning oil, dispersants and other pollutants in addition to physical and emotional stress. These exposures may have increased risk of myocardial infarction (MI) among oil spill workers. METHODS: Gulf Long-term Follow-up (GuLF) STUDY participants comprise individuals who either participated in the Deepwater Horizon response efforts or registered for safety training but were not hired...
August 25, 2018: Environmental Health: a Global Access Science Source
Sipeng Shen, Ruyang Zhang, Jinming Zhang, Yongyue Wei, Yichen Guo, Li Su, Feng Chen, David C Christiani
BACKGROUND: Increasing evidence suggests that welding fume exposure is associated with systemic inflammation. Although celluar metabolites may be associated with inflammation, there is limited information on metabolomic changes during welding fume exposure. Such changes may play an important role in the occurrence, development, and prevention of metal-associated diseases. We aim to investigate human metabolomics changes pre- and post-welding fume exposure. METHODS: This study included 52 boilermakers totally...
August 22, 2018: Environmental Health: a Global Access Science Source
Jennifer F Bobb, Birgit Claus Henn, Linda Valeri, Brent A Coull
BACKGROUND: Estimating the health effects of multi-pollutant mixtures is of increasing interest in environmental epidemiology. Recently, a new approach for estimating the health effects of mixtures, Bayesian kernel machine regression (BKMR), has been developed. This method estimates the multivariable exposure-response function in a flexible and parsimonious way, conducts variable selection on the (potentially high-dimensional) vector of exposures, and allows for a grouped variable selection approach that can accommodate highly correlated exposures...
August 20, 2018: Environmental Health: a Global Access Science Source
Matteo Scortichini, Francesca de'Donato, Manuela De Sario, Michela Leone, Christofer Åström, Ferran Ballester, Xavier Basagaña, Janos Bobvos, Antonio Gasparrini, Klea Katsouyanni, Timo Lanki, Bettina Menne, Mathilde Pascal, Paola Michelozzi
BACKGROUND: The association between heat and daily mortality and its temporal variation are well known. However, few studies have analyzed the inter-annual variations in both the risk estimates and impacts of heat. The aim is to estimate inter-annual variations in the effect of heat for a fixed temperature range, on mortality in 9 European cities included in the PHASE (Public Health Adaptation Strategies to Extreme weather events) project for the period 1990-2010. The second aim is to evaluate overall summer effects and heat-attributable deaths for each year included in the study period, considering the entire air temperature range (both mild and extreme temperatures)...
August 8, 2018: Environmental Health: a Global Access Science Source
Jae-Woo Kwon, Hee-Won Park, Woo Jin Kim, Man-Goo Kim, Seung-Joon Lee
BACKGROUND: Exposure to low levels of volatile organic compounds (VOCs) in ordinary life is suspected to be related to oxidative stress and decreased lung function. This study evaluated whether exposure to ambient VOCs in indoor air affects airway inflammation. METHODS: Thirty-four subjects from the hospital that had moved to a new building were enrolled. Symptoms of sick building syndrome, pulmonary function tests, and fractional exhaled nitric oxide (FeNO) were evaluated, and random urine samples were collected 1 week before and after the move...
August 7, 2018: Environmental Health: a Global Access Science Source
Philippe Grandjean
Identification and characterization of environmental hazards that impact human health must rely on the best possible science to inform and inspire appropriate public health intervention. The perfluorinated alkylate substances (PFASs) are persistent emerging pollutants that are now being recognized as important human health hazards. Although the PFASs have been produced for over 60 years, academic research on environmental health aspects has appeared only in the most recent 10 years or so. In the meantime, these persistent chemicals accumulated in the global environment...
July 31, 2018: Environmental Health: a Global Access Science Source
Nathalie Costet, Rémi Béranger, Ronan Garlantézec, Florence Rouget, Christine Monfort, Sylvaine Cordier, Fabienne Pelé, Cécile Chevrier
BACKGROUND: Numerous industries use organic solvents, and many workers from various occupational sectors are exposed to these known neurotoxicants, including pregnant women. Our objective is to explore whether occupational exposure of pregnant women to solvents may impair the neurodevelopment of their babies and consequently affect their behavior in childhood. METHODS: Within the French birth cohort PELAGIE, parents assessed their children's internalizing and externalizing behaviors using items from the Child Behavior Checklist and the Preschool Social Behavior Questionnaire at age 2, and the Strength and Difficulties Questionnaire at age 6...
July 27, 2018: Environmental Health: a Global Access Science Source
Isabelle Finke, Johan C de Jongste, Henriette A Smit, Alet H Wijga, Gerard H Koppelman, Judith Vonk, Bert Brunekreef, Ulrike Gehring
BACKGROUND: Air pollution has been found to adversely affect children's lung function. Forced expiratory volume in 1 s and forced vital capacity from spirometry have been studied most frequently, but measurements of airway resistance may provide additional information. We assessed associations of long-term air pollution exposure with airway resistance. METHODS: We measured airway resistance at age 8 with the interrupter resistance technique (Rint ) in participants of the Dutch PIAMA birth cohort study...
July 17, 2018: Environmental Health: a Global Access Science Source
Qiwen Zheng, Hui Liu, Jun Zhang, Dafang Chen
BACKGROUND: The relationship between particle matters (PMs) and cardiac arrhythmia has been investigated in numerous studies. However, evidence from developing countries is limited. The aim of this study was to evaluate the association between ambient PMs and hospital admissions for cardiac arrhythmia in China and to examine the potential effect modifiers. METHODS: A time-stratified case-crossover analysis was conducted in 26 large Chinese cities. In total, we identified 175,265 hospital admissions for cardiac arrhythmia between January 2014 and December 2015 from electronic hospitalization summary reports...
July 16, 2018: Environmental Health: a Global Access Science Source
P Monica Lind, Samira Salihovic, Jordan Stubleski, Anna Kärrman, Lars Lind
BACKGROUND: It has previously been reported that the environmental contaminants perfluoroalkyl substances (PFASs) are linked to atherosclerosis in cross-sectional studies. Since cross-sectional studies could be subject to reverse causation, the purpose of this study was to analyze if the longitudinal changes in PFASs during a 10-year follow-up were related to the change in carotid artery intima-media thickness (IMT, ultrasound) during the same period. METHODS: In the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study, 1016 individuals were investigated at age 70; 826 of them were reinvestigated at age 75 and 602 at age 80 years...
July 3, 2018: Environmental Health: a Global Access Science Source
Ann Aschengrau, Lisa G Gallagher, Michael Winter, Lindsey J Butler, M Patricia Fabian, Veronica M Vieira
BACKGROUND: Residents of Massachusetts and Rhode Island were exposed to tetrachloroethylene (PCE)-contaminated drinking water from 1968 through the early 1990s when the solvent was used to apply a vinyl liner to drinking water mains to address taste and odor problems. Few studies have examined the risk of fetal death among women exposed to solvent-contaminated drinking water. Two previous investigations found moderate increases in the risk of stillbirth among highly exposed women; however, these results were based on a small number of cases...
July 3, 2018: Environmental Health: a Global Access Science Source
Bo-Yi Yang, Zhengmin Min Qian, Michael G Vaughn, Steven W Howard, John Phillip Pemberton, Huimin Ma, Duo-Hong Chen, Li-Wen Hu, Xiao-Wen Zeng, Chuan Zhang, Yan-Peng Tian, Min Nian, Xiang Xiao, Guang-Hui Dong
BACKGROUND: Research regarding the interaction of ambient air pollution and overweight on prehypertension is scarce. We aimed to test whether overweight modifies the association between long-term exposure to ambient air pollution and prehypertension in Chinese adults. METHODS: A total of 16,188 Chinese adults, aged 18-74 years old, from 33 communities in 3 Northeastern Chinese cities were evaluated. Three-year average levels of particles with an aerodynamic diameter ≤ 10 μm (PM10 ), sulfur dioxides (SO2 ), nitrogen dioxides (NO2 ), and ozone (O3 ) were calculated at monitoring stations...
June 28, 2018: Environmental Health: a Global Access Science Source
Eileen McNeely, Irina Mordukhovich, Steven Staffa, Samuel Tideman, Sara Gale, Brent Coull
BACKGROUND: Flight attendants are an understudied occupational group, despite undergoing a wide range of adverse job-related exposures, including to known carcinogens. In our study, we aimed to characterize the prevalence of cancer diagnoses among U.S. cabin crew relative to the general population. METHODS: In 2014-2015, we surveyed participants of the Harvard Flight Attendant Health Study. We compared the prevalence of their self-reported cancer diagnoses to a contemporaneous cohort in the National Health and Nutrition Examination Survey (NHANES 2013-2014) using age-weighted standardized prevalence ratios (SPRs)...
June 26, 2018: Environmental Health: a Global Access Science Source
Jonathan Boss, Jingyi Zhai, Max T Aung, Kelly K Ferguson, Lauren E Johns, Thomas F McElrath, John D Meeker, Bhramar Mukherjee
BACKGROUND: Preterm birth is a significant public health concern and exposure to phthalates has been shown to be associated with an increased odds of preterm birth. Even modest reductions in gestational age at delivery could entail morbid consequences for the neonate and analyzing data with this additional information may be useful. In the present analysis, we consider gestational age at delivery as our outcome of interest and examine associations with multiple phthalates. METHODS: Women were recruited early in pregnancy as part of a prospective, longitudinal birth cohort at the Brigham and Women's Hospital in Boston, Massachusetts...
June 20, 2018: Environmental Health: a Global Access Science Source
Tamarra M James-Todd, Yu-Han Chiu, Carmen Messerlian, Lidia Mínguez-Alarcón, Jennifer B Ford, Myra Keller, John Petrozza, Paige L Williams, Xiaoyun Ye, Antonia M Calafat, Russ Hauser
BACKGROUND: Subfertile women are at increased risk of glucose intolerance in pregnancy. Based on epidemiologic studies, exposure to certain phthalates is associated with diabetes, elevated glucose, and increased insulin resistance. OBJECTIVES: To evaluate the association between urinary phthalate metabolites and pregnancy glucose levels in women seeking medically assisted reproduction. METHODS: We evaluated 245 women participating in a prospective cohort study based at a large fertility clinic who delivered live births and had data on pregnancy urinary phthalate metabolite concentrations and blood glucose levels...
June 14, 2018: Environmental Health: a Global Access Science Source
Lingyan Zhang, Zhao Zhang, Tao Ye, Maigeng Zhou, Chenzhi Wang, Peng Yin, Bin Hou
BACKGROUND: Many studies have reported an increased mortality risk from heat waves comparing with non-heat wave days. However, how much the mortality rate change with the heat intensity-vulnerability curve-is still unknown. Such unknown information makes the related managers impossible to assess scientifically life losses from heat waves, consequently fail in conducting suitable integrated risk management measures. METHODS: We used the heat wave intensity index (HWII) to characterize quantitatively the heat waves, then applied a distributed lag non-linear model to explore the area-specific definition of heat wave, and developed the vulnerability models on the relationships between HWII and mortality by age and by area...
June 11, 2018: Environmental Health: a Global Access Science Source
David C Bellinger
The purpose of this commentary is to consider whether the methods of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) can provide accurate estimates of the impact of developmental neurotoxicant exposures on population health. The discussion focuses on two concerns. First, GBD implicitly largely endorses a "high risk" or "disease" approach to estimating health loss rather than a "population-based" approach. Exposure to many developmental neurotoxicants is highly prevalent but, for most individuals, it does not affect functional health to such an extent that diagnostic criteria for a disease are met...
June 4, 2018: Environmental Health: a Global Access Science Source
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