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Biomedical Engineering Online

Chuan He, Rui Xu, Meidan Zhao, Yongming Guo, Shenglong Jiang, Feng He, Dong Ming
BACKGROUND AND PURPOSE: Turning while walking has a frequent occurrence in daily life. Evaluation of its dynamic stability will facilitate fall prevention and rehabilitation scheme. This knowledge is so limited that we set it as the first aim of this study. Another aim was to investigate spatiotemporal parameters during turning. METHODS: Fifteen healthy young adults were instructed to perform straight walking, 45° step turn to the left and 45° spin turn to the right at natural speed...
September 21, 2018: Biomedical Engineering Online
Yajun Zhao, Hongmei Liu, Suyashree P Bhonsle, Yilin Wang, Rafael V Davalos, Chenguo Yao
BACKGROUND: Irreversible electroporation (IRE) therapy relies on pulsed electric fields to non-thermally ablate cancerous tissue. Methods for evaluating IRE ablation in situ are critical to assessing treatment outcome. Analyzing changes in tissue impedance caused by electroporation has been proposed as a method for quantifying IRE ablation. In this paper, we assess the hypothesis that irreversible electroporation ablation outcome can be monitored using the impedance change measured by the electrode pairs not in use, getting more information about the ablation size in different directions...
September 20, 2018: Biomedical Engineering Online
Zhe Jiang, Zekuan Yu, Shouxin Feng, Zhiyu Huang, Yahui Peng, Jianxin Guo, Qiushi Ren, Yanye Lu
BACKGROUND: Fundus fluorescein angiography (FFA) imaging is a standard diagnostic tool for many retinal diseases such as age-related macular degeneration and diabetic retinopathy. High-resolution FFA images facilitate the detection of small lesions such as microaneurysms, and other landmark changes, in the early stages; this can help an ophthalmologist improve a patient's cure rate. However, only low-resolution images are available in most clinical cases. Super-resolution (SR), which is a method to improve the resolution of an image, has been successfully employed for natural and remote sensing images...
September 19, 2018: Biomedical Engineering Online
Thunyanoot Prasertsakul, Panya Kaimuk, Wipawee Chinjenpradit, Weerawat Limroongreungrat, Warakorn Charoensuk
BACKGROUND: Adults with sedentary lifestyles seem to face a higher risk of falling in their later years. Several causes, such as impairment of strength, coordination, and cognitive function, influence worsening health conditions, including balancing ability. Many modalities can be applied to improve the balance function and prevent falling. Several studies have also recorded the effects of balance training in elderly adults for fall prevention. Accordingly, the aim of this study is to define the effect of virtual reality-based balance training on motor learning and postural control abilities in healthy adults...
September 18, 2018: Biomedical Engineering Online
H H Draz, S R I Gabran, Mohamed Basha, Hassan Mostafa, Mohamed F Abu-Elyazeed, Amal Zaki
The new field of neuro-prosthetics focuses on the design and implementation of neural prostheses to restore some of the lost neural functions. The electrode-tissue contacts remain one of the major obstacles of neural prostheses microstructure. Recently, Microelectrode fabrication techniques have been developed to have a long-term and stable interface with the brain. In this paper, a comparative analysis of finite element models (FEM) for several electrode layouts is conducted. FEM involves parametric and sensitivity analysis to show the effects of the different design parameters on the electrode mechanical performance...
September 18, 2018: Biomedical Engineering Online
Pritika Dasgupta, Jessie VanSwearingen, Ervin Sejdic
BACKGROUND: There is considerable evidence that a person's gait is affected by cognitive load. Research in this field has implications for understanding the relationship between motor control and neurological conditions in aging and clinical populations. Accordingly, this pilot study evaluates the cognitive load based on gait accelerometry measurements of the walking patterns of ten healthy individuals (18-35 years old). METHODS: Data points were collected using six triaxial accelerometer sensors and treadmill pressure reports...
September 12, 2018: Biomedical Engineering Online
Sara Marceglia, Michael Rigby, Albert Alonso, Debbie Keeling, Lutz Kubitschke, Giuseppe Pozzi
BACKGROUND: Evidence shows that the implementation of information and communication technologies (ICT) enabled services supporting integrated dementia care represents an opportunity that faces multi-pronged challenges. First, the provision of dementia support is fragmented and often inappropriate. Second, available ICT solutions in this field do not address the full spectrum of support needs arising across an individual's whole dementia journey. Current solutions fail to harness the potential of available validated e-health services, such as telehealth and telecare, for the purposes of dementia care...
September 12, 2018: Biomedical Engineering Online
Masudur R Siddiquee, J Sebastian Marquez, Roozbeh Atri, Rodrigo Ramon, Robin Perry Mayrand, Ou Bai
BACKGROUND: The non-invasive nature of near-infrared spectroscopy (NIRS) makes it a widely accepted method for blood oxygenation measurement in various parts of the human body. One of the main challenges in this method lies in the successful removal of movement artefacts in the detected signal. In this respect, multi-channel inertia measurement unit (IMU) containing accelerometer, gyroscope and magnetometer can be used for better modelling of movement artefact than using accelerometer only, which as a result, movement artefact can be more accurately removed...
September 10, 2018: Biomedical Engineering Online
Sally Okun, Paul Wicks
The use of information and communication technologies for health (eHealth) delivered via mobile-based or digitally enhanced solutions (mHealth) have rapidly evolved. When used together across various mobile applications and devices eHealth and mHealth technologies have the ability to passively monitor behavior as an indicator of socialization and mood; accumulate a range of biomedical data such as weight and heart rate; and track metrics associated with activities including steps taken and hours slept. Yet, these technologies are insufficient for measuring the full array of data about an individual and the impact of that data on a person's current and future health...
September 6, 2018: Biomedical Engineering Online
Min-Ho Jun, Young Ju Jeon, Jung-Hee Cho, Young-Min Kim
BACKGROUND: Piezo-resistive pressure sensors are widely used for measuring pulse waves of the radial artery. Pulse sensors are generally fabricated with a cover layer because pressure sensors without a cover layer are fragile when they come into direct contact with the skin near the radial artery. However, no study has evaluated the dynamic pulse wave response of pulse sensors depending on the thickness and hardness of the cover layer. This study analyzed the dynamic pulse wave response according to the thickness and hardness of the cover layer and suggests an appropriate thickness and hardness for the design of pulse sensors with semiconductor device-based pressure sensors...
September 4, 2018: Biomedical Engineering Online
Oleksandr Makeyev
BACKGROUND: Superiority of noninvasive tripolar concentric ring electrodes over conventional disc electrodes in accuracy of surface Laplacian estimation has been demonstrated in a range of electrophysiological measurement applications. Recently, a general approach to Laplacian estimation for an (n + 1)-polar electrode with n rings using the (4n + 1)-point method has been proposed and used to introduce novel multipolar and variable inter-ring distances electrode configurations...
August 30, 2018: Biomedical Engineering Online
Hongze Pan, Zhi Xu, Hong Yan, Yue Gao, Zhanghuang Chen, Jinzhong Song, Yu Zhang
BACKGROUND: Several different lying positions, such as lying on the left side, supine, lying on the right side and prone position, existed when healthy people fell asleep. This article explored the influence of lying positions on the shape of ECG (electrocardiograph) waveform during sleep, and then lying position classification based on ECG waveform features and random forest was achieved. METHODS: By means of de-noising the overnight sleep ECG data from ISRUC website dataset, as well as extracting the waveform features, we calculated a total of 30 ECG waveform features, including 2 newly proposed features, S/R and ∠QSR...
August 30, 2018: Biomedical Engineering Online
Jarosław Żyłkowski, Grzegorz Rosiak, Dominik Spinczyk
BACKGROUND: The geometry of the vessels is easy to assess in novel 3D studies. It has significant influence on flow patterns and this way the evolution of vascular pathologies such as aneurysms and atherosclerosis. It is essential to develop robust system for vascular anatomy measurement and digital description allowing for assessment of big numbers of vessels. METHODS: A semiautomatic, robust, integrated method for vascular anatomy measurements and mathematical description are presented...
August 29, 2018: Biomedical Engineering Online
Chang Liu, Xi Wu, Xi Yu, YuanYan Tang, Jian Zhang, JiLiu Zhou
BACKGROUND: Magnetic resonance (MR) images are usually limited by low spatial resolution, which leads to errors in post-processing procedures. Recently, learning-based super-resolution methods, such as sparse coding and super-resolution convolution neural network, have achieved promising reconstruction results in scene images. However, these methods remain insufficient for recovering detailed information from low-resolution MR images due to the limited size of training dataset. METHODS: To investigate the different edge responses using different convolution kernel sizes, this study employs a multi-scale fusion convolution network (MFCN) to perform super-resolution for MRI images...
August 25, 2018: Biomedical Engineering Online
Chunli Qin, Demin Yao, Yonghong Shi, Zhijian Song
As the most common examination tool in medical practice, chest radiography has important clinical value in the diagnosis of disease. Thus, the automatic detection of chest disease based on chest radiography has become one of the hot topics in medical imaging research. Based on the clinical applications, the study conducts a comprehensive survey on computer-aided detection (CAD) systems, and especially focuses on the artificial intelligence technology applied in chest radiography. The paper presents several common chest X-ray datasets and briefly introduces general image preprocessing procedures, such as contrast enhancement and segmentation, and bone suppression techniques that are applied to chest radiography...
August 22, 2018: Biomedical Engineering Online
Yuqin Ma, Bo Zhang, Yuzhen Zhang, Yun Dong, Ruiqing Zhang
BACKGROUND: Patients with uremia have high cardiovascular disease morbidity and mortality despite having normal left ventricular ejection fraction (LVEF). Longitudinal strain (LS) can be associated with subtle changes in LV systolic function. The aim of this study was to use two-dimensional speckle-tracking echocardiography (2DSTE) to assess subclinical LV myocardial dysfunction and to explore strain-changing regularities in uremic patients with LVEF ≥ 55%. METHODS: The study population included 40 uremic patients and 40 healthy volunteers...
August 20, 2018: Biomedical Engineering Online
Jingsheng Tang, Yadong Liu, Dewen Hu, ZongTan Zhou
BACKGROUND: Electroencephalogram-based brain-computer interfaces (BCIs) represent novel human machine interactive technology that allows people to communicate and interact with the external world without relying on their peripheral muscles and nervous system. Among BCI systems, brain-actuated wheelchairs are promising systems for the rehabilitation of severely motor disabled individuals who are unable to control a wheelchair by conventional interfaces. Previous related studies realized the easy use of brain-actuated wheelchairs that enable people to navigate the wheelchair through simple commands; however, these systems rely on offline calibration of the environment...
August 20, 2018: Biomedical Engineering Online
Martin Bartoš, Tomáš Suchý, René Foltán
BACKGROUND: Collagen-based scaffolds provide a promising option for the treatment of bone defects. One of the key parameters of such scaffolds consists of porosity, including pore size. However, to date, no agreement has been found with respect to the methodology for pore size evaluation. Since the determination of the exact pore size value is not possible, the comparison of the various methods applied is complicated. Hence, this study focuses on the comparison of two widely-used methods for the characterization of porosity-scanning electron microscopy (SEM) and micro-computed tomography (micro-CT)...
August 17, 2018: Biomedical Engineering Online
Michele Lanza, Robert Koprowski, Mario Bifani Sconocchia
BACKGROUND: To improve accuracy of IOLMaster (Carl Zeiss, Jena, Germany) in corneal power measurement after myopic excimer corneal refractive surgery (MECRS) using multivariate polynomial analysis (MPA). METHODS: One eye of each of 403 patients (mean age 31.53 ± 8.47 years) was subjected to MECRS for a myopic defect, measured as spherical equivalent, ranging from - 9.50 to - 1 D (mean - 4.55 ± 2.20 D). Each patient underwent a complete eye examination and IOLMaster scan before surgery and at 1, 3 and 6 months follow up...
August 13, 2018: Biomedical Engineering Online
Aácio José Zimbico, Diogo Watchel Granado, Fabio Kurt Schneider, Joaquim Miguel Maia, Amauri Amorin Assef, Nivaldo Schiefler, Eduardo Tavares Costa
BACKGROUND: The eigenspace generalized sidelobe canceller (EGSC) beamformer combined with a signal-to-noise ratio (SNR) dependent coherence factor (CF) is suggested for coherent plane wave compounding (PW) imaging. Conventional CF based methods such as generalized CF and subarray CF can improve the image quality, however, they are not suitable for low SNR. On the other hand, the EGSC CF based approach can introduce improvements in image quality, however, in PW imaging is susceptible to suffer from degradation due to low SNR which leads to a poor image quality...
August 13, 2018: Biomedical Engineering Online
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