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Biomedical Engineering Online

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https://www.readbyqxmd.com/read/28427411/tendon-motion-tracking-in-an-ultrasound-image-sequence-using-optical-flow-based-block-matching
#1
Bo-I Chuang, Jian-Han Hsu, Li-Chieh Kuo, I-Ming Jou, Fong-Chin Su, Yung-Nien Sun
BACKGROUND: Tendon motion, which is commonly observed using ultrasound imaging, is one of the most important features used in tendinopathy diagnosis. However, speckle noise and out-of-plane issues make the tracking process difficult. Manual tracking is usually time consuming and often yields inconsistent results between users. METHODS: To automatically track tendon motion in ultrasound images, we developed a new method that combines the advantages of optical flow and multi-kernel block matching...
April 20, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28427408/time-averaged-simulated-microgravity-tasmg-inhibits-proliferation-of-lymphoma-cells-l-540-and-hdlm-2-using-a-3d-clinostat
#2
Yoon Jae Kim, Ae Jin Jeong, Myungjoon Kim, Chiwon Lee, Sang-Kyu Ye, Sungwan Kim
BACKGROUND: Gravity is omnipresent on Earth; however, humans in space, such as astronauts at the International Space Station, experience microgravity. Long-term exposure to microgravity is considered to elicit physiological changes, such as muscle atrophy, in the human body. In addition, certain types of cancer cells demonstrate inhibited proliferation under condition of time-averaged simulated microgravity (taSMG). However, the response of human Hodgkin's lymphoma cancer cells to reduced gravity, and the associated physiological changes in these cells, have not been elucidated...
April 20, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28412952/rayleigh-maximum-likelihood-bilateral-filter-for-ultrasound-image-enhancement
#3
Haiyan Li, Jun Wu, Aimin Miao, Pengfei Yu, Jianhua Chen, Yufeng Zhang
BACKGROUND: Ultrasound imaging plays an important role in computer diagnosis since it is non-invasive and cost-effective. However, ultrasound images are inevitably contaminated by noise and speckle during acquisition. Noise and speckle directly impact the physician to interpret the images and decrease the accuracy in clinical diagnosis. Denoising method is an important component to enhance the quality of ultrasound images; however, several limitations discourage the results because current denoising methods can remove noise while ignoring the statistical characteristics of speckle and thus undermining the effectiveness of despeckling, or vice versa...
April 17, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28410616/breast-masses-in-mammography-classification-with-local-contour-features
#4
Haixia Li, Xianjing Meng, Tingwen Wang, Yuchun Tang, Yilong Yin
BACKGROUND: Mammography is one of the most popular tools for early detection of breast cancer. Contour of breast mass in mammography is very important information to distinguish benign and malignant mass. Contour of benign mass is smooth and round or oval, while malignant mass has irregular shape and spiculated contour. Several studies have shown that 1D signature translated from 2D contour can describe the contour features well. METHODS: In this paper, we propose a new method to translate 2D contour of breast mass in mammography into 1D signature...
April 14, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28410615/signal-to-noise-ratio-evaluation-of-magnetic-resonance-images-in-the-presence-of-an-ultrasonic-motor
#5
Peyman Shokrollahi, James M Drake, Andrew A Goldenberg
BACKGROUND: Safe robot-assisted intervention using magnetic resonance imaging (MRI) guidance requires the precise control of assistive devices, and most currently available tools are rarely MRI-compatible. To obtain high precision, it is necessary to characterize and develop existing MRI-safe actuators for use in a high magnetic field (≥3 T). Although an ultrasonic motor (USM) is considered to be an MRI-safe actuator, and can be used in the vicinity of a high field scanner, its presence interferes with MR images...
April 14, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28407768/a-study-of-noninvasive-fractional-flow-reserve-derived-from-a-simplified-method-based-on-coronary-computed-tomography-angiography-in-suspected-coronary-artery-disease
#6
Changzheng Shi, Dong Zhang, Kunlin Cao, Tao Zhang, Liangping Luo, Xin Liu, Heye Zhang
BACKGROUND: The invasive fractional flow reserve has been considered the gold standard for identifying ischaemia-related stenosis in patients with suspected coronary artery disease. Determining non-invasive FFR based on coronary computed tomographic angiography datasets using computational fluid dynamics tends to be a demanding process. Therefore, the diagnostic performance of a simplified method for the calculation of FFRCTA requires further evaluation. OBJECTIVES: The aim of this study was to investigate the diagnostic performance of FFRCTA calculated based on a simplified method by referring to the invasive FFR in patient-specific coronary arteries and clinical decision-making...
April 14, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28407773/minimally-invasive-patient-specific-beat-by-beat-estimation-of-left-ventricular-time-varying-elastance
#7
Shaun Davidson, Chris Pretty, Antoine Pironet, Shun Kamoi, Joel Balmer, Thomas Desaive, J Geoffrey Chase
BACKGROUND: The aim of this paper was to establish a minimally invasive method for deriving the left ventricular time varying elastance (TVE) curve beat-by-beat, the monitoring of which's inter-beat evolution could add significant new data and insight to improve diagnosis and treatment. The method developed uses the clinically available inputs of aortic pressure, heart rate and baseline end-systolic volume (via echocardiography) to determine the outputs of left ventricular pressure, volume and dead space volume, and thus the TVE curve...
April 13, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28376803/characterization-of-biomechanical-properties-of-cells-through-dielectrophoresis-based-cell-stretching-and-actin-cytoskeleton-modeling
#8
Guohua Bai, Ying Li, Henry K Chu, Kaiqun Wang, Qiulin Tan, Jijun Xiong, Dong Sun
BACKGROUND: Cytoskeleton is a highly dynamic network that helps to maintain the rigidity of a cell, and the mechanical properties of a cell are closely related to many cellular functions. This paper presents a new method to probe and characterize cell mechanical properties through dielectrophoresis (DEP)-based cell stretching manipulation and actin cytoskeleton modeling. METHODS: Leukemia NB4 cells were used as cell line, and changes in their biological properties were examined after chemotherapy treatment with doxorubicin (DOX)...
April 4, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28356126/starch-pcl-composite-nanofibers-by-co-axial-electrospinning-technique-for-biomedical-applications
#9
B Komur, F Bayrak, N Ekren, M S Eroglu, F N Oktar, Z A Sinirlioglu, S Yucel, O Guler, O Gunduz
BACKGROUND: In this study, starch and polycaprolactone (PCL), composite nanofibers were fabricated by co-axial needle electrospinning technique. Processing parameters such as polymer concentration, flow rate and voltage had a marked influence on the composite fiber diameter. Fourier transform infrared spectroscopy, scanning electron microscopy (SEM), mechanical and physical properties (such as density, viscosity and electrical conductivity) of the composite fibres were evaluated. Moreover, a cell culture test was performed in order to determine their cytotoxicity for wound dressing application...
March 29, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28351368/nonrigid-registration-with-corresponding-points-constraint-for-automatic-segmentation-of-cardiac-dsct-images
#10
Xuesong Lu, Rongqian Yang, Qinlan Xie, Shanxing Ou, Yunfei Zha, Defeng Wang
BACKGROUND: Dual-source computed tomography (DSCT) is a very effective way for diagnosis and treatment of heart disease. The quantitative information of spatiotemporal DSCT images can be important for the evaluation of cardiac function. To avoid the shortcoming of manual delineation, it is imperative to develop an automatic segmentation technique for 4D cardiac images. METHODS: In this paper, we implement the heart segmentation-propagation framework based on nonrigid registration...
March 28, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28347343/modeling-electrical-stimulation-of-retinal-ganglion-cell-with-optimizing-additive-noises-for-reducing-threshold-and-energy-consumption
#11
Jing Wu, Menghua Jin, Qingli Qiao
BACKGROUND: Epiretinal prosthesis is one device for the treatment of blindness, which target retinal ganglion cells (RGCs) by electrodes on retinal surface. The stimulating current of epiretinal prosthesis is an important factor that influences the safety threshold and visual perception. Stochastic resonance (SR) can be used to enhance the detection and transmission of subthreshold stimuli in neurons. Here, it was assumed that SR was a potential way to improve the performance of epiretinal prosthesis...
March 27, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28340588/comparison-of-the-com-fcp-inclination-angle-and-other-mediolateral-stability-indicators-for-turning
#12
COMPARATIVE STUDY
Rui Xu, Xin Wang, Jiajia Yang, Feng He, Xin Zhao, Hongzhi Qi, Peng Zhou, Dong Ming
BACKGROUND: Studies have shown that turning is associated with more instability than straight walking and instability increases with turning angles. However, the precise relationship of changes in stability with the curvature and step length of turning is not clear. The traditional center of mass (COM)-center of pressure (COP) inclination angle requires the use of force plates. A COM-foot contact point (FCP) inclination angle derived from kinematic data is proposed in this study as a measure of the stability of turning...
March 24, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28335790/physical-mechanism-and-modeling-of-heat-generation-and-transfer-in-magnetic-fluid-hyperthermia-through-n%C3%A3-elian-and-brownian-relaxation-a-review
#13
REVIEW
Suriyanto, E Y K Ng, S D Kumar
Current clinically accepted technologies for cancer treatment still have limitations which lead to the exploration of new therapeutic methods. Since the past few decades, the hyperthermia treatment has attracted the attention of investigators owing to its strong biological rationales in applying hyperthermia as a cancer treatment modality. Advancement of nanotechnology offers a potential new heating method for hyperthermia by using nanoparticles which is termed as magnetic fluid hyperthermia (MFH). In MFH, superparamagnetic nanoparticles dissipate heat through Néelian and Brownian relaxation in the presence of an alternating magnetic field...
March 23, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28327144/computational-medical-imaging-and-hemodynamics-framework-for-functional-analysis-and-assessment-of-cardiovascular-structures
#14
REVIEW
Kelvin K L Wong, Defeng Wang, Jacky K L Ko, Jagannath Mazumdar, Thu-Thao Le, Dhanjoo Ghista
Cardiac dysfunction constitutes common cardiovascular health issues in the society, and has been an investigation topic of strong focus by researchers in the medical imaging community. Diagnostic modalities based on echocardiography, magnetic resonance imaging, chest radiography and computed tomography are common techniques that provide cardiovascular structural information to diagnose heart defects. However, functional information of cardiovascular flow, which can in fact be used to support the diagnosis of many cardiovascular diseases with a myriad of hemodynamics performance indicators, remains unexplored to its full potential...
March 21, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28320423/in-vivo-estimation-of-the-shoulder-joint-center-of-rotation-using-magneto-inertial-sensors-mri-based-accuracy-and-repeatability-assessment
#15
M Crabolu, D Pani, L Raffo, M Conti, P Crivelli, A Cereatti
BACKGROUND: The human gleno-humeral joint is normally represented as a spherical hinge and its center of rotation is used to construct humerus anatomical axes and as reduction point for the computation of the internal joint moments. The position of the gleno-humeral joint center (GHJC) can be estimated by recording ad hoc shoulder joint movement following a functional approach. In the last years, extensive research has been conducted to improve GHJC estimate as obtained from positioning systems such as stereo-photogrammetry or electromagnetic tracking...
March 21, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28320451/personal-medical-electronic-devices-and-walk-through-metal-detector-security-systems-assessing-electromagnetic-interference-effects
#16
Joshua Guag, Bisrat Addissie, Donald Witters
BACKGROUND: There have been concerns that Electromagnetic security systems such as walk-through metal detectors (WTMDs) can potentially cause electromagnetic interference (EMI) in certain active medical devices including implantable cardiac pacemakers and implantable neurostimulators. Incidents of EMI between WTMDs and active medical devices also known as personal medical electronic devices (PMED) continue to be reported. This paper reports on emission measurements of sample WTMDs and testing of 20 PMEDs in a WTMD simulation system...
March 20, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28253881/an-lp-0%C3%A2-%C3%A2-%C3%A2-p%C3%A2-%C3%A2-%C3%A2-1-norm-regularized-image-reconstruction-scheme-for-breast-dot-with-non-negative-constraint
#17
Bingyuan Wang, Wenbo Wan, Yihan Wang, Wenjuan Ma, Limin Zhang, Jiao Li, Zhongxing Zhou, Huijuan Zhao, Feng Gao
BACKGROUND: In diffuse optical tomography (DOT), the image reconstruction is often an ill-posed inverse problem, which is even more severe for breast DOT since there are considerably increasing unknowns to reconstruct with regard to the achievable number of measurements. One common way to address this ill-posedness is to introduce various regularization methods. There has been extensive research regarding constructing and optimizing objective functions. However, although these algorithms dramatically improved reconstruction images, few of them have designed an essentially differentiable objective function whose full gradient is easy to obtain to accelerate the optimization process...
March 3, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28241829/real-time-qrs-complex-detection-using-dfa-and-regular-grammar
#18
Salah Hamdi, Asma Ben Abdallah, Mohamed Hedi Bedoui
BACKGROUND: The sequence of Q, R, and S peaks (QRS) complex detection is a crucial procedure in electrocardiogram (ECG) processing and analysis. We propose a novel approach for QRS complex detection based on the deterministic finite automata with the addition of some constraints. This paper confirms that regular grammar is useful for extracting QRS complexes and interpreting normalized ECG signals. A QRS is assimilated to a pair of adjacent peaks which meet certain criteria of standard deviation and duration...
February 28, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28219432/personalized-heterogeneous-deformable-model-for-fast-volumetric-registration
#19
Weixin Si, Xiangyun Liao, Qiong Wang, Pheng Ann Heng
BACKGROUND: Biomechanical deformable volumetric registration can help improve safety of surgical interventions by ensuring the operations are extremely precise. However, this technique has been limited by the accuracy and the computational efficiency of patient-specific modeling. METHODS: This study presents a tissue-tissue coupling strategy based on penalty method to model the heterogeneous behavior of deformable body, and estimate the personalized tissue-tissue coupling parameters in a data-driven way...
February 20, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28209171/integrated-strategy-for-in-vitro-characterization-of-a-bileaflet-mechanical-aortic-valve
#20
Francesca Maria Susin, Stefania Espa, Riccardo Toninato, Stefania Fortini, Giorgio Querzoli
BACKGROUND: Haemodynamic performance of heart valve prosthesis can be defined as its ability to fully open and completely close during the cardiac cycle, neither overloading heart work nor damaging blood particles when passing through the valve. In this perspective, global and local flow parameters, valve dynamics and blood damage safety of the prosthesis, as well as their mutual interactions, have all to be accounted for when assessing the device functionality. Even though all these issues have been and continue to be widely investigated, they are not usually studied through an integrated approach yet, i...
February 16, 2017: Biomedical Engineering Online
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