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Biomedical Engineering Online

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https://www.readbyqxmd.com/read/29157240/automatic-diagnosis-of-imbalanced-ophthalmic-images-using-a-cost-sensitive-deep-convolutional-neural-network
#1
Jiewei Jiang, Xiyang Liu, Kai Zhang, Erping Long, Liming Wang, Wangting Li, Lin Liu, Shuai Wang, Mingmin Zhu, Jiangtao Cui, Zhenzhen Liu, Zhuoling Lin, Xiaoyan Li, Jingjing Chen, Qianzhong Cao, Jing Li, Xiaohang Wu, Dongni Wang, Jinghui Wang, Haotian Lin
BACKGROUND: Ocular images play an essential role in ophthalmological diagnoses. Having an imbalanced dataset is an inevitable issue in automated ocular diseases diagnosis; the scarcity of positive samples always tends to result in the misdiagnosis of severe patients during the classification task. Exploring an effective computer-aided diagnostic method to deal with imbalanced ophthalmological dataset is crucial. METHODS: In this paper, we develop an effective cost-sensitive deep residual convolutional neural network (CS-ResCNN) classifier to diagnose ophthalmic diseases using retro-illumination images...
November 21, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29157238/evaluation-of-normal-swallowing-functions-by-using-dynamic-high-density-surface-electromyography-maps
#2
Mingxing Zhu, Bin Yu, Wanzhang Yang, Yanbing Jiang, Lin Lu, Zhen Huang, Shixiong Chen, Guanglin Li
BACKGROUND: Swallowing is a continuous process with substantive interdependencies among different muscles, and it plays a significant role in our daily life. The aim of this study was to propose a novel technique based on high-density surface electromyography (HD sEMG) for the evaluation of normal swallowing functions. METHODS: A total of 96 electrodes were placed on the front neck to acquire myoelectric signals from 12 healthy subjects while they were performing different swallowing tasks...
November 21, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29141673/a-customized-fixation-plate-with-novel-structure-designed-by-topological-optimization-for-mandibular-angle-fracture-based-on-finite-element-analysis
#3
Yun-Feng Liu, Ying-Ying Fan, Xian-Feng Jiang, Dale A Baur
BACKGROUND: The purpose of this study was to design a customized fixation plate for mandibular angle fracture using topological optimization based on the biomechanical properties of the two conventional fixation systems, and compare the results of stress, strain and displacement distributions calculated by finite element analysis (FEA). METHODS: A three-dimensional (3D) virtual mandible was reconstructed from CT images with a mimic angle fracture and a 1 mm gap between two bone segments, and then a FEA model, including volume mesh with inhomogeneous bone material properties, three loading conditions and constraints (muscles and condyles), was created to design a customized plate using topological optimization method, then the shape of the plate was referenced from the stress concentrated area on an initial part created from thickened bone surface for optimal calculation, and then the plate was formulated as "V" pattern according to dimensions of standard mini-plate finally...
November 15, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29137676/a-medium-invasiveness-multi-level-patient-s-specific-template-for-pedicle-screw-placement-in-the-scoliosis-surgery
#4
Farhad Azimifar, Kamran Hassani, Amir Hossein Saveh, Farhad Tabatabai Ghomsheh
BACKGROUND: Several methods including free-hand technique, fluoroscopic guidance, image-guided navigation, computer-assisted surgery system, robotic platform and patient's specific templates are being used for pedicle screw placement. These methods have screw misplacements and are not always easy to be applied. Furthermore, it is necessary to expose completely a large portions of the spine in order to access fit entirely around the vertebrae. METHODS: In this study, a multi-level patient's specific template with medium invasiveness was proposed for pedicle screw placement in the scoliosis surgery...
November 14, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29132360/neoanalysis-a-python-based-toolbox-for-quick-electrophysiological-data-processing-and-analysis
#5
Bo Zhang, Ji Dai, Tao Zhang
BACKGROUND: In a typical electrophysiological experiment, especially one that includes studying animal behavior, the data collected normally contain spikes, local field potentials, behavioral responses and other associated data. In order to obtain informative results, the data must be analyzed simultaneously with the experimental settings. However, most open-source toolboxes currently available for data analysis were developed to handle only a portion of the data and did not take into account the sorting of experimental conditions...
November 13, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29132359/portable-wireless-neurofeedback-system-of-eeg-alpha-rhythm-enhances-memory
#6
Ting-Ying Wei, Da-Wei Chang, You-De Liu, Chen-Wei Liu, Chung-Ping Young, Sheng-Fu Liang, Fu-Zen Shaw
BACKGROUND: Effect of neurofeedback training (NFT) on enhancement of cognitive function or amelioration of clinical symptoms is inconclusive. The trainability of brain rhythm using a neurofeedback system is uncertainty because various experimental designs are used in previous studies. The current study aimed to develop a portable wireless NFT system for alpha rhythm and to validate effect of the NFT system on memory with a sham-controlled group. METHODS: The proposed system contained an EEG signal analysis device and a smartphone with wireless Bluetooth low-energy technology...
November 13, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29121932/hemodynamics-analysis-of-the-serial-stenotic-coronary-arteries
#7
Xin Liu, Changnong Peng, Yufa Xia, Zhifan Gao, Pengcheng Xu, Xiaoqing Wang, Zhanchao Xian, Youbing Yin, Liqun Jiao, Defeng Wang, Lin Shi, Wenhua Huang, Xin Liu, Heye Zhang
Coronary arterial stenoses, particularly serial stenoses in a single branch, are responsible for complex hemodynamic properties of the coronary arterial trees, and the uncertain prognosis of invasive intervention. Critical information of the blood flow redistribution in the stenotic arterial segments is required for the adequate treatment planning. Therefore, in this study, an image based non-invasive functional assessment is performed to investigate the hemodynamic significances of serial stenoses. Twenty patient-specific coronary arterial trees with different combinations of stenoses were reconstructed from the computer tomography angiography for the evaluation of the hemodynamics...
November 9, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29096638/empirical-study-of-seven-data-mining-algorithms-on-different-characteristics-of-datasets-for-biomedical-classification-applications
#8
Yiyan Zhang, Yi Xin, Qin Li, Jianshe Ma, Shuai Li, Xiaodan Lv, Weiqi Lv
BACKGROUND: Various kinds of data mining algorithms are continuously raised with the development of related disciplines. The applicable scopes and their performances of these algorithms are different. Hence, finding a suitable algorithm for a dataset is becoming an important emphasis for biomedical researchers to solve practical problems promptly. METHODS: In this paper, seven kinds of sophisticated active algorithms, namely, C4.5, support vector machine, AdaBoost, k-nearest neighbor, naïve Bayes, random forest, and logistic regression, were selected as the research objects...
November 2, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29096634/prediction-of-high-airway-pressure-using-a-non-linear-autoregressive-model-of-pulmonary-mechanics
#9
Ruby Langdon, Paul D Docherty, Christoph Schranz, J Geoffrey Chase
BACKGROUND: For mechanically ventilated patients with acute respiratory distress syndrome (ARDS), suboptimal PEEP levels can cause ventilator induced lung injury (VILI). In particular, high PEEP and high peak inspiratory pressures (PIP) can cause over distension of alveoli that is associated with VILI. However, PEEP must also be sufficient to maintain recruitment in ARDS lungs. A lung model that accurately and precisely predicts the outcome of an increase in PEEP may allow dangerous high PIP to be avoided, and reduce the incidence of VILI...
November 2, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29084564/global-patch-matching-gpm-for-freehand-3d-ultrasound-reconstruction
#10
Weijian Cong, Jian Yang, Danni Ai, Hong Song, Gang Chen, Xiaohui Liang, Ping Liang, Yongtian Wang
BACKGROUND: 3D ultrasound volume reconstruction from B-model ultrasound slices can provide more clearly and intuitive structure of tissue and lesion for the clinician. METHODS: This paper proposes a novel Global Path Matching method for the 3D reconstruction of freehand ultrasound images. The proposed method composes of two main steps: bin-filling scheme and hole-filling strategy. For the bin-filling scheme, this study introduces two operators, including the median absolute deviation and the inter-quartile range absolute deviation, to calculate the invariant features of each voxel in the 3D ultrasound volume...
October 30, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29084547/near-field-effect-on-elasticity-measurement-for-cartilage-bone-structure-using-lamb-wave-method
#11
Hao Xu, Shigao Chen, Kai-Nan An, Zong-Ping Luo
BACKGROUND: Cartilage elasticity changes with cartilage degeneration. Hence, cartilage elasticity detection might be an alternative to traditional imaging methods for the early diagnosis of osteoarthritis. Based on the wave propagation measurement, Shear wave elastography (SWE) become an emerging non-invasive elasticity detection method. The wave propagation model, which is affected by tissue shapes, is crucial for elasticity estimating in SWE. However, wave propagation model for cartilage was unclear...
October 30, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29073912/automatic-non-proliferative-diabetic-retinopathy-screening-system-based-on-color-fundus-image
#12
Zhitao Xiao, Xinpeng Zhang, Lei Geng, Fang Zhang, Jun Wu, Jun Tong, Philip O Ogunbona, Chunyan Shan
BACKGROUND: Non-proliferative diabetic retinopathy is the early stage of diabetic retinopathy. Automatic detection of non-proliferative diabetic retinopathy is significant for clinical diagnosis, early screening and course progression of patients. METHODS: This paper introduces the design and implementation of an automatic system for screening non-proliferative diabetic retinopathy based on color fundus images. Firstly, the fundus structures, including blood vessels, optic disc and macula, are extracted and located, respectively...
October 26, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29061181/paroxysmal-atrial-fibrillation-recognition-based-on-multi-scale-wavelet-%C3%AE-entropy
#13
Yi Xin, Yizhang Zhao
BACKGROUND: This study proposed an effective method based on the wavelet multi-scale α-entropy features of heart rate variability (HRV) for the recognition of paroxysmal atrial fibrillation (PAF). This new algorithm combines wavelet decomposition and non-linear analysis methods. The PAF signal, the signal distant from PAF, and the normal sinus signals can be identified and distinguished by extracting the characteristic parameters from HRV signals and analyzing their quantification indexes...
October 23, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29041932/stamps-development-and-verification-of-swallowing-kinematic-analysis-software
#14
Woo Hyung Lee, Changmook Chun, Han Gil Seo, Seung Hak Lee, Byung-Mo Oh
BACKGROUND: Swallowing impairment is a common complication in various geriatric and neurodegenerative diseases. Swallowing kinematic analysis is essential to quantitatively evaluate the swallowing motion of the oropharyngeal structures. This study aims to develop a novel swallowing kinematic analysis software, called spatio-temporal analyzer for motion and physiologic study (STAMPS), and verify its validity and reliability. METHODS: STAMPS was developed in MATLAB, which is one of the most popular platforms for biomedical analysis...
October 17, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29017484/solar-uv-exposure-among-outdoor-workers-in-denmark-measured-with-personal-uv-b-dosimeters-technical-and-practical-feasibility
#15
Kasper Grandahl, Ole Steen Mortensen, David Zim Sherman, Brian Køster, Paul-Anker Lund, Kristina Sophie Ibler, Paul Eriksen
BACKGROUND: Exposure to solar ultraviolet radiation is a well-known cause of skin cancer. This is problematic for outdoor workers. In Denmark alone, occupational skin cancer poses a significant health and safety risk for around 400,000 outdoor workers. Objective measures of solar ultraviolet radiation exposure are needed to help resolve this problem. This can be done using personal ultraviolet radiation dosimeters. METHODS: We consider technical and practical feasibility of measuring individual solar ultraviolet exposure at work and leisure in professions with different á priori temporal high-level outdoor worktime, using aluminium gallium nitride (AlGaN) photodiode detector based personal UV-B dosimeters...
October 10, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28974217/low-power-transcutaneous-current-stimulator-for-wearable-applications
#16
David Karpul, Gregory K Cohen, Gaetano D Gargiulo, André van Schaik, Sarah McIntyre, Paul P Breen
BACKGROUND: Peripheral neuropathic desensitization associated with aging, diabetes, alcoholism and HIV/AIDS, affects tens of millions of people worldwide, and there is little or no treatment available to improve sensory function. Recent studies that apply imperceptible continuous vibration or electrical stimulation have shown promise in improving sensitivity in both diseased and healthy participants. This class of interventions only has an effect during application, necessitating the design of a wearable device for everyday use...
October 3, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28974212/diabetic-foot-ulcer-mobile-detection-system-using-smart-phone-thermal-camera-a-feasibility-study
#17
Luay Fraiwan, Mohanad AlKhodari, Jolu Ninan, Basil Mustafa, Adel Saleh, Mohammed Ghazal
BACKGROUND: Nowadays, the whole world is being concerned with a major health problem, which is diabetes. A very common symptom of diabetes is the diabetic foot ulcer (DFU). The early detection of such foot complications can protect diabetic patients from any dangerous stages that develop later and may require foot amputation. This work aims at building a mobile thermal imaging system that can be used as an indicator for possible developing ulcers. METHODS: The proposed system consists of a thermal camera connected to a Samsung smart phone, which is used to acquire thermal images...
October 3, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28974207/study-of-the-variations-of-fall-induced-hip-fracture-risk-between-right-and-left-femurs-using-ct-based-fea
#18
Tanvir R Faisal, Yunhua Luo
BACKGROUND: Hip fracture of elderly people-suffering from osteoporosis-is a severe public health concern, which can be reduced by providing a prior assessment of hip fracture risk. Image-based finite element analysis (FEA) has been considered an effective computational tool to assess the hip fracture risk. Considering the femoral neck region is the weakest, fracture risk indicators (FRI) are evaluated for both single-legged stance and sideways fall configurations and are compared between left and right femurs of each subject...
October 3, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28946919/biosignals-learning-and-synthesis-using-deep-neural-networks
#19
David Belo, João Rodrigues, João R Vaz, Pedro Pezarat-Correia, Hugo Gamboa
BACKGROUND: Modeling physiological signals is a complex task both for understanding and synthesize biomedical signals. We propose a deep neural network model that learns and synthesizes biosignals, validated by the morphological equivalence of the original ones. This research could lead the creation of novel algorithms for signal reconstruction in heavily noisy data and source detection in biomedical engineering field. METHOD: The present work explores the gated recurrent units (GRU) employed in the training of respiration (RESP), electromyograms (EMG) and electrocardiograms (ECG)...
September 25, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28934967/building-a-resistance-to-ignition-testing-device-for-sunglasses-and-analysing-data-a-continuing-study-for-sunglasses-standards
#20
Renan Magri, Mauro Masili, Fernanda Oliveira Duarte, Liliane Ventura
BACKGROUND: Sunglasses popularity skyrocketed since its advent. The ongoing trend led to the creation of standards to protect consumers from injuries and secondary hazards due to spectacles use. In Brazil, the corresponding standard is NBR ISO 12312-1:2015 and since there is no mandatory testing, evaluating sunglasses performance provides an insight into compliance with the standard. In a continuing revision of sunglasses standards requirements, resistance to ignition is one of the concerns, since sunglasses should be protected from burning into flames at a pre-determined temperature, which may protect user of getting their sunglasses into flames if some, cigarette sparks reaches the spectacles, as an example...
September 21, 2017: Biomedical Engineering Online
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