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Biomedical Engineering Online

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https://www.readbyqxmd.com/read/29338745/study-of-correlation-between-wall-shear-stress-and-elasticity-in-atherosclerotic-carotid-arteries
#1
Bo Zhang, Junyi Gu, Ming Qian, Lili Niu, Dhanjoo Ghista
OBJECTIVE: This paper presents the use of the texture matching method to measure the rabbit carotid artery elasticity value of the experimental group and control group respectively. It compares the experimental rabbits, when they are prompted by pathological histology to be at the period of carotid atherosclerosis fatty streaks and fiber plaques, with the control group. METHODS: We have used ultrasound linear array probe for scanning the rabbit carotid arteries...
January 16, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29338729/computational-study-of-the-effects-of-arterial-bifurcation-on-the-temperature-distribution-during-cryosurgery
#2
Yong-Chang Zheng, Jun-Hong Wu, Zhi-Zhu He, Shao-Jiong Huang
BACKGROUND: Thermally significant blood flows into locally cooled diseased tissues and warm them during cryosurgery so that the iceball is often hard to cover the whole diseased volume. This paper is aimed at investigating the effects of large arterial bifurcation on the temperature distribution during cryosurgery through simulation method. METHODS: A parametric geometry model is introduced to construct a close-to-real arterial bifurcation. The three-dimensional transient conjugate heat transfer between bifurcated artery and solid tissues with phase change during cryosurgery is performed by finite volume method...
January 16, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29335011/generalized-estimation-of-the-ventilatory-distribution-from-the-multiple-breath-washout-a-bench-evaluation-study
#3
Gabriel Casulari Motta-Ribeiro, Frederico Caetano Jandre, Hermann Wrigge, Antonio Giannella-Neto
BACKGROUND: The multiple-breath washout (MBW) is able to provide information about the distribution of ventilation-to-volume (v/V) ratios in the lungs. However, the classical, all-parallel model may return skewed results due to the mixing effect of a common dead space. The aim of this work is to examine whether a novel mathematical model and algorithm is able to estimate v/V of a physical model, and to compare its results with those of the classical model. The novel model takes into account a dead space in series with the parallel ventilated compartments, allows for variable tidal volume (VT) and end-expiratory lung volume (EELV), and does not require a ideal step change of the inert gas concentration...
January 15, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29334937/perspectives-on-setting-limits-for-rf-contact-currents-a-commentary
#4
REVIEW
Richard A Tell, Christopher A Tell
BACKGROUND: Limits for exposure to radiofrequency (RF) contact currents are specified in the two dominant RF safety standards and guidelines developed by the Institute of Electrical and Electronics Engineers (IEEE) and the International Commission on Non-Ionizing Radiation Protection (ICNIRP). These limits are intended to prevent RF burns when contacting RF energized objects caused by high local tissue current densities. We explain what contact currents are and review some history of the relevant limits with an emphasis on so-called "touch" contacts, i...
January 15, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29310661/temperature-elevation-in-the-human-brain-and-skin-with-thermoregulation-during-exposure-to-rf-energy
#5
Sachiko Kodera, Jose Gomez-Tames, Akimasa Hirata
BACKGROUND: Two international guidelines/standards for human protection from electromagnetic fields define the specific absorption rate (SAR) averaged over 10 g of tissue as a metric for protection against localized radio frequency field exposure due to portable devices operating below 3-10 GHz. Temperature elevation is suggested to be a dominant effect for exposure at frequencies higher than 100 kHz. No previous studies have evaluated temperature elevation in the human head for local exposure considering thermoregulation...
January 8, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29258590/investigation-of-red-blood-cell-mechanical-properties-using-afm-indentation-and-coarse-grained-particle-method
#6
Sarah Barns, Marie Anne Balanant, Emilie Sauret, Robert Flower, Suvash Saha, YuanTong Gu
BACKGROUND: Red blood cells (RBCs) deform significantly and repeatedly when passing through narrow capillaries and delivering dioxygen throughout the body. Deformability of RBCs is a key characteristic, largely governed by the mechanical properties of the cell membrane. This study investigated RBC mechanical properties using atomic force microscopy (AFM) with the aim to develop a coarse-grained particle method model to study for the first time RBC indentation in both 2D and 3D. This new model has the potential to be applied to further investigate the local deformability of RBCs, with accurate control over adhesion, probe geometry and position of applied force...
December 19, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29258517/r-wave-synchronised-atrial-pacing-in-pediatric-patients-with-postoperative-junctional-ectopic-tachycardia-the-atrioventricular-interval-investigated-by-computational-analysis-and-clinical-evaluation
#7
Andreas Entenmann, Miriam Michel, Bruno Ismer, Roman Gebauer
BACKGROUND: R-wave synchronised atrial pacing is an effective temporary pacing therapy in infants with postoperative junctional ectopic tachycardia. In the technique currently used, adverse short or long intervals between atrial pacing and ventricular sensing (AP-VS) may be observed during routine clinical practice. OBJECTIVES: The aim of the study was to analyse outcomes of R-wave synchronised atrial pacing and the relationship between maximum tracking rates and AP-VS intervals...
December 19, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29212516/a-finite-element-model-of-the-lower-limb-during-stance-phase-of-gait-cycle-including-the-muscle-forces
#8
Arnaud Diffo Kaze, Stefan Maas, Pierre-Jean Arnoux, Claude Wolf, Dietrich Pape
BACKGROUND: Results of finite element (FE) analyses can give insight into musculoskeletal diseases if physiological boundary conditions, which include the muscle forces during specific activities of daily life, are considered in the FE modelling. So far, many simplifications of the boundary conditions are currently made. This study presents an approach for FE modelling of the lower limb for which muscle forces were included. METHODS: The stance phase of normal gait was simulated...
December 7, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29208019/correlation-between-quantitative-analysis-of-wall-shear-stress-and-intima-media-thickness-in-atherosclerosis-development-in-carotid-arteries
#9
Bo Zhang, Junyi Gu, Ming Qian, Lili Niu, Hui Zhou, Dhanjoo Ghista
BACKGROUND: This paper presents quantitative analysis of blood flow shear stress by measuring the carotid arterial wall shear stress (WSS) and the intima-media thickness (IMT) of experimental rabbits fed with high-fat feedstuff on a weekly basis in order to cause atherosclerosis. METHODS: This study is based on establishing an atherosclerosis model of high-fat rabbits, and measuring the rabbits' common carotid arterial WSS of the experimental group and control group on a weekly basis...
December 6, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29202876/application-of-two-parameter-scoliometer-values-for-predicting-scoliotic-cobb-angle
#10
Hsuan-Hsiao Ma, Ching-Lung Tai, Lih-Huei Chen, Chi-Chien Niu, Wen-Jer Chen, Po-Liang Lai
BACKGROUND: Adolescent idiopathic scoliosis, in which obvious curves are visible in radiographic images, is also seen in combination with lumps in the back. These lumps contribute to inclination, which can be measured by a scoliometer. To the authors' knowledge, there are no previous formulas combining thoracic and lumbar scoliometer values simultaneously to predict thoracic and lumbar Cobb angles, respectively. This study aimed to create more accurate two-parameter mathematical formulas for predicting thoracic and lumbar Cobb angles...
December 4, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29169367/image-based-quantitative-analysis-of-tear-film-lipid-layer-thickness-for-meibomian-gland-evaluation
#11
Hyeonha Hwang, Hee-Jae Jeon, Kin Choong Yow, Ho Sik Hwang, EuiHeon Chung
BACKGROUND: Dry eye syndrome is one of the most common ocular diseases, and meibomian gland dysfunction (MGD) is the leading cause of evaporative dry eye syndrome. When the tear film lipid layer becomes thin due to obstructive or hyposecretory meibomian gland dysfunction, the excessive evaporation of the aqueous layer can occur, and this causes evaporative dry eye syndrome. Thus, measuring the lipid layer thickness (LLT) is essential for accurate diagnosis and proper treatment of evaporative dry eye syndrome...
November 23, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29169361/differentiation-of-human-adipose-derived-stem-cells-into-cardiomyocyte-like-cells-in-fibrin-scaffold-by-a-histone-deacetylase-inhibitor
#12
Zahra Bagheri-Hosseinabadi, Parvin Salehinejad, Seyed Alireza Mesbah-Namin
BACKGROUND: Human adipose-derived stem cells (hADSCs) are capable of differentiating into many cells such as cardiac cells. Different types of inducers are used for cardiac cell differentiation, but this question still remains to be investigated, which one is the best. The aim of this paper was to investigate the effect of combination of fibrin scaffold and trichostatin A (TSA), for differentiation of hADSCs into cardiomyocyte-like cells. METHODS: After approval of characteristics of hADSCs and fibrin scaffold, hADSCs were cultured in fibrin scaffold with 10 µM TSA for 72 h and kept in standard conditions for 4 weeks...
November 23, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29157240/automatic-diagnosis-of-imbalanced-ophthalmic-images-using-a-cost-sensitive-deep-convolutional-neural-network
#13
Jiewei Jiang, Xiyang Liu, Kai Zhang, Erping Long, Liming Wang, Wangting Li, Lin Liu, Shuai Wang, Mingmin Zhu, Jiangtao Cui, Zhenzhen Liu, Zhuoling Lin, Xiaoyan Li, Jingjing Chen, Qianzhong Cao, Jing Li, Xiaohang Wu, Dongni Wang, Jinghui Wang, Haotian Lin
BACKGROUND: Ocular images play an essential role in ophthalmological diagnoses. Having an imbalanced dataset is an inevitable issue in automated ocular diseases diagnosis; the scarcity of positive samples always tends to result in the misdiagnosis of severe patients during the classification task. Exploring an effective computer-aided diagnostic method to deal with imbalanced ophthalmological dataset is crucial. METHODS: In this paper, we develop an effective cost-sensitive deep residual convolutional neural network (CS-ResCNN) classifier to diagnose ophthalmic diseases using retro-illumination images...
November 21, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29157238/evaluation-of-normal-swallowing-functions-by-using-dynamic-high-density-surface-electromyography-maps
#14
Mingxing Zhu, Bin Yu, Wanzhang Yang, Yanbing Jiang, Lin Lu, Zhen Huang, Shixiong Chen, Guanglin Li
BACKGROUND: Swallowing is a continuous process with substantive interdependencies among different muscles, and it plays a significant role in our daily life. The aim of this study was to propose a novel technique based on high-density surface electromyography (HD sEMG) for the evaluation of normal swallowing functions. METHODS: A total of 96 electrodes were placed on the front neck to acquire myoelectric signals from 12 healthy subjects while they were performing different swallowing tasks...
November 21, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29141673/a-customized-fixation-plate-with-novel-structure-designed-by-topological-optimization-for-mandibular-angle-fracture-based-on-finite-element-analysis
#15
Yun-Feng Liu, Ying-Ying Fan, Xian-Feng Jiang, Dale A Baur
BACKGROUND: The purpose of this study was to design a customized fixation plate for mandibular angle fracture using topological optimization based on the biomechanical properties of the two conventional fixation systems, and compare the results of stress, strain and displacement distributions calculated by finite element analysis (FEA). METHODS: A three-dimensional (3D) virtual mandible was reconstructed from CT images with a mimic angle fracture and a 1 mm gap between two bone segments, and then a FEA model, including volume mesh with inhomogeneous bone material properties, three loading conditions and constraints (muscles and condyles), was created to design a customized plate using topological optimization method, then the shape of the plate was referenced from the stress concentrated area on an initial part created from thickened bone surface for optimal calculation, and then the plate was formulated as "V" pattern according to dimensions of standard mini-plate finally...
November 15, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29137676/a-medium-invasiveness-multi-level-patient-s-specific-template-for-pedicle-screw-placement-in-the-scoliosis-surgery
#16
Farhad Azimifar, Kamran Hassani, Amir Hossein Saveh, Farhad Tabatabai Ghomsheh
BACKGROUND: Several methods including free-hand technique, fluoroscopic guidance, image-guided navigation, computer-assisted surgery system, robotic platform and patient's specific templates are being used for pedicle screw placement. These methods have screw misplacements and are not always easy to be applied. Furthermore, it is necessary to expose completely a large portions of the spine in order to access fit entirely around the vertebrae. METHODS: In this study, a multi-level patient's specific template with medium invasiveness was proposed for pedicle screw placement in the scoliosis surgery...
November 14, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29132360/neoanalysis-a-python-based-toolbox-for-quick-electrophysiological-data-processing-and-analysis
#17
Bo Zhang, Ji Dai, Tao Zhang
BACKGROUND: In a typical electrophysiological experiment, especially one that includes studying animal behavior, the data collected normally contain spikes, local field potentials, behavioral responses and other associated data. In order to obtain informative results, the data must be analyzed simultaneously with the experimental settings. However, most open-source toolboxes currently available for data analysis were developed to handle only a portion of the data and did not take into account the sorting of experimental conditions...
November 13, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29132359/portable-wireless-neurofeedback-system-of-eeg-alpha-rhythm-enhances-memory
#18
Ting-Ying Wei, Da-Wei Chang, You-De Liu, Chen-Wei Liu, Chung-Ping Young, Sheng-Fu Liang, Fu-Zen Shaw
BACKGROUND: Effect of neurofeedback training (NFT) on enhancement of cognitive function or amelioration of clinical symptoms is inconclusive. The trainability of brain rhythm using a neurofeedback system is uncertainty because various experimental designs are used in previous studies. The current study aimed to develop a portable wireless NFT system for alpha rhythm and to validate effect of the NFT system on memory with a sham-controlled group. METHODS: The proposed system contained an EEG signal analysis device and a smartphone with wireless Bluetooth low-energy technology...
November 13, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29121932/hemodynamics-analysis-of-the-serial-stenotic-coronary-arteries
#19
Xin Liu, Changnong Peng, Yufa Xia, Zhifan Gao, Pengcheng Xu, Xiaoqing Wang, Zhanchao Xian, Youbing Yin, Liqun Jiao, Defeng Wang, Lin Shi, Wenhua Huang, Xin Liu, Heye Zhang
Coronary arterial stenoses, particularly serial stenoses in a single branch, are responsible for complex hemodynamic properties of the coronary arterial trees, and the uncertain prognosis of invasive intervention. Critical information of the blood flow redistribution in the stenotic arterial segments is required for the adequate treatment planning. Therefore, in this study, an image based non-invasive functional assessment is performed to investigate the hemodynamic significances of serial stenoses. Twenty patient-specific coronary arterial trees with different combinations of stenoses were reconstructed from the computer tomography angiography for the evaluation of the hemodynamics...
November 9, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29096638/empirical-study-of-seven-data-mining-algorithms-on-different-characteristics-of-datasets-for-biomedical-classification-applications
#20
Yiyan Zhang, Yi Xin, Qin Li, Jianshe Ma, Shuai Li, Xiaodan Lv, Weiqi Lv
BACKGROUND: Various kinds of data mining algorithms are continuously raised with the development of related disciplines. The applicable scopes and their performances of these algorithms are different. Hence, finding a suitable algorithm for a dataset is becoming an important emphasis for biomedical researchers to solve practical problems promptly. METHODS: In this paper, seven kinds of sophisticated active algorithms, namely, C4.5, support vector machine, AdaBoost, k-nearest neighbor, naïve Bayes, random forest, and logistic regression, were selected as the research objects...
November 2, 2017: Biomedical Engineering Online
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