Acta Informatica Medica : AIM

BACKGROUND: An endodontic treatment consists in cleaning, shaping and filling the root canal system. Irrigation is the chemical part of the process that ensures the total removal of debris. Activating the irrigation solution will improve and accelerate the process. OBJECTIVE: The aim of the study is to evaluate the removal of debris and smear layer at 1, 3, and 5mm from the foramen after needle irrigation, EndoActivator® and Irrisafe®. Sixty single-rooted teeth were prepared using Primary WaveOne Gold®...

BACKGROUND: Transfusion treatment during life, as well as pregnancy in women, can stimulate the sensitization of the person who received blood, which after the transfusion of blood products can result in the occurrence of moderate to very severe posttransfusion reactions. OBJECTIVE: The aim of this study was to examine the specificity and frequency of antierythrocyte antibodies during the pretransfusion treatment of patients depending on the gender, to determine the origin of antibodies in patients serum, as well as to examine their clinical significance...

BACKGROUND: Inflammatory cytokines like Matrix Metalloproteinases (MMPs) are associated with the destruction observed in periodontal disease. There has been evidence of significant increases in MMP levels in patients with systemic disorders, such as Diabetes Mellitus (DM), which is associated with microvascular complications, causing increased MMP activity, directly or indirectly, due to oxidative stress. OBJECTIVE: The aim of this study was conducted in order to assess wound healing using MMP-8 levels in GCF of diabetics with chronic periodontitis after diode laser assisted flap surgery...

BACKGROUND: The body has a thermoregulation setting where when it gets hot, the body responds by dilating blood vessels or vasodilation, otherwise it gets a cold response, which causes narrowing of blood vessels or vasoconstriction. The thermal conditioning system is a system that can influence the baby in terms of its thermal quality. So that the baby can feel a comfortable environment or not. Skin temperature is a fundamental factor in heat exchange between the body and its environment...

BACKGROUND: Birt-Hogg-Dube syndrome (BHDS), also known as Hornstein-Knickenberg syndrome is a rare, autosomal dominant genetic disorder characterized by a triad of clinical manifestations: skin fibrofolliculomas, renal tumors, and multiple pulmonary cysts. The exact incidence of BHDS syndrome is unknown. This hereditary syndrome is caused by mutations in the folliculin (FLCN) gene, located on chromosome 17p11.2, which encodes the folliculin protein. OBJECTIVE: This case report aims to highlight the importance of increased vigilance and long-term follow-up in BHDS patients, even decades after surgical intervention, to detect and manage potential pulmonary complications effectively...

BACKGROUND: Cardiosurgical patients can be often anemic, and preoperative anaemia is associated with increased postoperative complications, as well as morbidity and mortality. OBJECTIVE: The present study was conducted aiming to determine the influence of lower preoperative hematocrit values on the early postoperative recovery of patients undergoing elective off-pump coronary artery bypass grafting (OPCABG). METHODS: Our retrospective study included 150 patients who underwent elective OPCABG surgery from September 2021 to December 2022 at the Clinic for Cardiovascular Surgery University of Sarajevo...

BACKGROUND: Colorectal cancer (CRC) is a diverse disease with various clinical, pathological and molecular features that affect tumor biological behavior, treatment response and prognosis. OBJECTIVE: The aim of this study was to evaluate the correlation between metabolic 18F-FDG PET/CT parameters (SUVmax, MTV and TLG) and CEA in recurrent and metastatic CRC and to evaluate prognostic value of metabolic 18F-FDG PET/CT parameters in recurrent and metastatic CRC. METHODS: A descriptive study of 100 patients with previously detected and surgically treated CRC referred to PET/CT with a suspicion of recurrent or metastatic CRC...

No abstract text is available yet for this article.

BACKGROUND: Obstructive sleep apnea (OSA) is a common disorder characterized by recurrent upper airway collapse during sleep, leading to neurological and cardiovascular adverse effects. OBJECTIVE: The present study aimed to explore seasonal compliance with Continuous Positive Airway Pressure (CPAP) therapy among OSA patients in Greece. METHODS: Data from 954 OSA patients using CPAP devices were collected during summer and winter months. Factors evaluated included the Apnea-Hypopnea Index (AHI), mask type, mask leaks, and hours of CPAP device usage...

BACKGROUND: Osteoarthritis of the knee (OA) and osteoporosis are two conditions that have a significant impact on society, have a great impact on quality of life, and can lead to functional impairment. However, the relationship between knee OA and osteoporosis is unclear. OBJECTIVE: The aim of this study was to examine if there is a link between symptomatic advanced knee osteoarthritis and low bone mineral density. METHODS: A total of 430 patients with symptomatic and advanced radiographic knee OA served as participants in this study...

BACKGROUND: The book "An Impossible Decision - the Life Interrupted by Uncertainty"has been published by Avicena Publisher in Sarajevo, Bosnia and Herzegovina in 2023 - ISBN: 978-9958-720-76-5. OBJECTIVE: The aim of this article is to analize what is the most rational and ethical way to treat people facing life-and-death decisions and how do we exactly communicate these inevitable uncertainties that all of us will sooner or later face? METHODS: Author of the book shows real-life relevance to patients often left alone to make these difficult decisions...

BACKGROUND: Prion diseases or TSE diseases are a group of neurodegenerative disorders that manifest in several forms in humans, such as Kuru disease, Creutzfeldt‒Jakob disease (CJD), Gerstmann-Sträussler-Scheinker syndrome (GSS) and fatal familial insomnia. OBJECTIVE: In this study, we propose a multimodular hypothesis of prion diseases. According to this hypothesis, a prion disease manifests because of the interaction of two genetic modules, such as the PRNP gene module and that of the gene or genes responsible for one or more chaperones, with one or some chemical module on whose structure the products of the genes or genetic modules interact...

BACKGROUND: Coronary artery disease (CAD) is a major public health issue and a leading cause of death globally. It is one of the most common indications for surgical intervention. There are a lot of different techniques, including CABG, which consists of two approaches: sternotomy and mini-thoracotomy. Different techniques have been developed to improve surgical outcomes, including the use of machine for extracorporal circulation (on-pump) or without it (off-pump). OBJECTIVE: The objective of this study was to assess whether off-pump CABG offers superior short-term outcomes compared to traditional on-pump CABG in patients undergoing isolated CABG...

BACKGROUND: Osseointegration is defined as the direct structural and functional connection between neo-formed bone and dental implants. Among the parameters suggested to predominantly influencing the establishment of a successful osseointegration is the quality of the implant surface, which may enhance the strength and speed of this biomechanical process. OBJECTIVE: The purpose of this study was to evaluate the ability of a novel laser-treated surface, compared to sandblasted, large-grit, acid-etched (SLA) surfaces, to enhance and accelerate implant integration in delayed implant placement...

BACKGROUND: Acne vulgaris is one of the most common dermatological diseases, especially in adolescents and young adults. OBJECTIVE: The current study aimed to compare teledermatology versus face-to-face consultation in the follow-up of patients with mild-to-moderate acne. METHODS: In this investigator-initiated, parallel arms, open-label, randomized clinical trial, after screening, participants were randomly assigned in a 1:1 ratio to be followed up through teledermatology or standard face-to-face consultations for a period of 6 months...

BCKGROUND: The diagnosis of chronic rhinosinusitis (CRS) is confirmed by subjectively assessing a patient's complaints and objectively by a computed tomography scan (CT scan) and nasoendoscopic examination. The Lund Mackay (LM) score on paranasal sinus CT scans and the Modified Lund Kennedy (MLK) nasoendoscopic score have more advantages than other scores. OBJECTIVE: The aim of this study was to determine the correlation between the LM score on paranasal sinus CT scans and the nasoendoscopic MLK score in patients with CRS at Dr...

BACKGROUND: This study brings innovation oriented to the development of e-health services to improve the performance of healthcare and hospital care in free-living activities. OBJECTIVE: This article seeks to propose an innovative mobile software that enables the contextualization of clinical data, while integrating the fundamental functionalities and usability criteria of a mobile health (mhealth) system. METHODS: We examine the utility of a context-sensitive mobile electrocardiogram (ECG) collection system for the detection of cardiovascular diseases for patients in free-living conditions...

No abstract text is available yet for this article.

BACKGROUND: Immune-mediated inflammatory injury among systemic lupus erythematosus (SLE) individuals may be involved by dendritic cells (DCs) abnormality though the underlying mechanism remains incompletely understood. OBJECTIVE: This study aimed to elaborate MSCs' potential in suppressing abnormal DCs cell function on peripheral blood mononuclear cells (PBMCs) among SLE patients. METHODS: MSCs were isolated from human umbilical cord blood...

BACKGROUND: Heart attack, or cardiac arrest, became a leading cause of death after the turn of the century. Defibrillation is one of the most important medical advances of the twentieth century. Defibrillation is a critical step in the treatment of cardiac arrest as it can be the only way to restore a normal heart rhythm and save the life of the individual. However, it is important to note that defibrillation is only effective if it is performed quickly and in conjunction with other life-saving measures such as cardiopulmonary resuscitation (CPR)...