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Journal of the Royal College of Physicians of Edinburgh

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https://www.readbyqxmd.com/read/29741539/in-response-to-thyroid-hormone-replacement-a-counterblast-to-guidelines
#1
G P Leese, R V Flynn, T M MacDonald, C Schofield, A D Mackie
No abstract text is available yet for this article.
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741538/sanatoria-revisited-sunlight-and-health
#2
C P Bredin
No abstract text is available yet for this article.
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741537/copper-deficiency-and-myelopathy-after-bariatric-surgery-authors-reply
#3
J Oben, P Cordero
No abstract text is available yet for this article.
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741536/copper-deficiency-and-myelopathy-after-bariatric-surgery
#4
O M Jolobe
No abstract text is available yet for this article.
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741535/amanita-muscaria-fly-agaric-from-a-shamanistic-hallucinogen-to-the-search-for-acetylcholine
#5
M R Lee, E Dukan, I Milne
The mushroom Amanita muscaria (fly agaric) is widely distributed throughout continental Europe and the UK. Its common name suggests that it had been used to kill flies, until superseded by arsenic. The bioactive compounds occurring in the mushroom remained a mystery for long periods of time, but eventually four hallucinogens were isolated from the fungus: muscarine, muscimol, muscazone and ibotenic acid. The shamans of Eastern Siberia used the mushroom as an inebriant and a hallucinogen. In 1912, Henry Dale suggested that muscarine (or a closely related substance) was the transmitter at the parasympathetic nerve endings, where it would produce lacrimation, salivation, sweating, bronchoconstriction and increased intestinal motility...
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741534/a-brief-look-at-the-history-of-the-deaconess-hospital-edinburgh-1894-1990
#6
E R McNeill, D Wright, A K Demetriades
The Deaconess Hospital, Edinburgh, opened in 1894 and was the first establishment of its kind in the UK, maintained and wholly funded as it was by the Reformed Church. Through its 96-year lifetime it changed and evolved to time and circumstance. It was a school: for the training of nurses and deaconesses who took their practical skills all over the world. It was a sanctum: for the sick-poor before the NHS. It was a subsidiary: for the bigger hospitals of Edinburgh after amalgamation into the NHS. It was a specialised centre: as the Urology Department in Edinburgh and the Scottish Lithotripter centre...
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741533/cultivating-compassionate-care-why-does-it-matter-and-what-can-we-do-to-promote-it
#7
E Ward, J Gillies, L Grant, A Elder, J Burton, C Ryan, C Quinn
No abstract text is available yet for this article.
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741532/some-thoughts-on-compassion-inspired-by-sir-thomas-legge
#8
S O'Mahony
No abstract text is available yet for this article.
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741531/cost-effectiveness-of-physical-fitness-training-for-stroke-survivors
#9
M Collins, E Clifton, F van Wijck, G E Mead
Background Physical fitness is impaired after stroke, yet fitness training after stroke reduces disability. Several international guidelines recommend that fitness training be incorporated as part of stroke rehabilitation. However, information about cost-effectiveness is limited. Methods A decision tree model was used to estimate the cost-effectiveness of a fitness programme for stroke survivors vs. relaxation (control group). This was based on a published randomised controlled trial, from which evidence about quality of life was used to estimate Quality Adjusted Life Years...
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741530/the-uk-academic-foundation-programmes-are-the-objectives-being-met
#10
R Ologunde, G Sismey, T Kelley
Background Since the Academic Foundation Programme was established in the UK in 2005 a number of trainees have participated in this programme; however, there are few published national data on the experiences of these academic trainees. We aimed to assess the perceived value and challenges of training on the AFP. Methods In March 2017, an anonymous electronic questionnaire was distributed to all Academic Foundation Programme trainees in the UK, via their local foundation school administrators. RESULTS: Fifty-six respondents completed the survey from 9 out of the 15 Academic Units of Application...
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741529/the-scottish-academic-foundation-year-programme-what-why-and-how
#11
G P Currie, S Messeder, K Walker
The Foundation Programme is well established in the UK and serves as the generic training scheme into which newly qualified doctors enter after gaining a medical degree. Although individual programmes have many differences, the range of competencies needing to be fulfilled to progress is uniform across Scotland and the rest of the UK. Some final year medical undergraduates may apply for the Academic Foundation Programme; this is designed to facilitate exposure to academic medicine over and above the clinical experience offered to Foundation Year doctors...
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741528/blogging-for-medical-education-a-personal-view
#12
C Thaung
Medical education has evolved considerably from didactic and lecture-based to self-directed, especially with the rise of online platforms. While large organisations may commission or create entire customised courses for online learning, the individual teacher has a more modest and immediately accessible tool with which to disseminate information to students and other learners: blogging.
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741527/a-rare-feature-of-advanced-copd
#13
N Bezawada, G P Currie
No abstract text is available yet for this article.
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741526/diagnosing-dementia-with-lewy-bodies-new-diagnostic-criteria
#14
S Liyanagedera, R M Bracewell, A J Larner
No abstract text is available yet for this article.
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741525/orbita-much-ado-about-nothing
#15
A G Zaman
No abstract text is available yet for this article.
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741524/disseminated-herpes-simplex-virus-a-case-of-eczema-herpeticum-causing-viral-encephalitis
#16
C Finlow, J Thomas
Eczema herpeticum is a dermatological emergency causing a mortality of up to 10% if untreated. It frequently presents in a localised form and rarely disseminates via haematogenous spread with pulmonary, hepatic, ocular and neurological manifestations. Although it commonly appears on a background of atopic dermatitis, many other dermatological conditions have been described preceding this disease. Eczema herpeticum can be easily mistaken for folliculitis and is often treated accordingly with antibacterial drugs; therefore patients will often deteriorate before a diagnosis of eczema herpeticum has been considered...
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741523/fulminant-streptococcal-toxic-shock-syndrome
#17
S Zavala, M Arias, P Legua
We present a case of a previously healthy 37-year-old male who developed fever, nausea, vomiting, diarrhoea, and hypovolaemia. Within 5.5 h he presented with tachycardia, tachypnoea, became hypotensive and displayed a diffuse erythematous rash. In the following hours he developed persistent hypotension, acute respiratory distress syndrome, liver failure, kidney failure and disseminated intravascular coagulation. A diagnosis of toxic shock syndrome was made, but despite antibiotic therapy, immunoglobulin administration, and supportive measures, the patient died 50 h after presentation...
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741522/an-incidental-finding-of-severe-hyperferritinaemia-a-lesson-to-be-learned
#18
T B Fretwell, M Hanna
Haemophagocytic lymphohistiocytosis is a rare, under-recognised and often misdiagnosed condition, characterised by a hyperinflammatory response to malignancy or infection. In this case, the cause was a bone marrow isolated anaplastic large cell lymphoma without radiological evidence of systemic disease, a phenomenon rarely described. We present the case of a previously fit and well 64-year-old female who presented on multiple occasions to primary and secondary care in a stable condition with an undifferentiated illness with the only consistent feature being a marked, unexplained hyperferritinaemia...
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741521/an-outbreak-of-japanese-encephalitis-in-a-non-endemic-region-of-north-east-india
#19
H McNaughton, A Singh, S A Khan
Background There are few comprehensive reports of epidemic Japanese encephalitis in a previously unaffected region. We report our experience of a first-ever outbreak of it in Sonitpur District, Assam, India, with 45 laboratorycon confirmed cases at a single hospital. Method Between 2 July and 11 August 2008, patients meeting the WHO definition of acute encephalitis syndrome were assessed in a single hospital and had tests including blood and cerebrospinal fluid for Japanese encephalitis antibody titres. Results Ninety-six cases meeting the definition of acute encephalitis syndrome were identified with 45 cases of Japanese encephalitis confirmed by cerebrospinal fluid or blood results...
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29741520/alk-immunohistochemistry-is-highly-sensitive-and-specific-for-the-detection-of-alk-translocated-lung-adenocarcinomas-lessons-from-an-audit-of-lung-cancer-molecular-testing
#20
Y C Kheng, K Walsh, L Williams, W A Wallace, D J Harrison, A Oniscu
Background The approval of novel targeted treatments for epidermal growth factor receptor (EGFR)-positive and anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer has led to the increased requirement for mutation testing. Results We report our experience of ALK testing with immunohistochemistry (IHC) and fluorescence in-situ hybridisation (FISH) and present the prevalence of EGFR, Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) and ALK mutations. From January 2011 to May 2014, we found mutation rates of EGFR, KRAS and ALK to be 10...
March 2018: Journal of the Royal College of Physicians of Edinburgh
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