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Journal of the Royal College of Physicians of Edinburgh

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https://www.readbyqxmd.com/read/30191923/treatable-alternative-causes-of-extreme-hyperferritinaemia
#1
LETTER
O Mp Jolobe
No abstract text is available yet for this article.
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191922/author-s-reply-to-more-on-igg4-related-pulmonary-disease
#2
LETTER
A Rl Medford
No abstract text is available yet for this article.
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191921/more-on-igg4-related-pulmonary-disease
#3
LETTER
O Mp Jolobe
No abstract text is available yet for this article.
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191920/ebola-selective-memory-and-educational-costs
#4
LETTER
D M Brett-Major
No abstract text is available yet for this article.
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191919/sir-alexander-morison-and-the-physiognomy-of-mental-diseases-part-1
#5
A Beveridge
Sir Alexander Morison's The Physiognomy of Mental Diseases and the original art work that formed the basis of the book have not had the scholarly attention they deserve. The published book and the commissioned portraits have not been studied in any detail. Historians have tended to offer cursory assessments that have reflected their own preconceived ideas rather than properly engaging with the material. This is a pity because Morison's work is a rich source that tells us much about the history of psychiatry...
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191918/george-riddoch-1888-1947-the-driving-force-behind-the-treatment-of-spinal-injuries-in-the-uk-during-the-second-world-war
#6
J R Silver, M-F Weiner
The development of the successful treatment of spinal injuries has been inextricably linked to Sir Ludwig Guttmann and Stoke Mandeville Hospital. The role of George Riddoch has largely been ignored or mentioned merely in relation to Ludwig Guttmann and his appointment as the first Resident Medical Officer at Stoke Mandeville Hospital. Riddoch's contribution was far more significant. New material, comprising Riddoch's letters and memoranda written between 1939 and 1944, reveals his paramount involvement in the setting up of spinal injury units across the UK between 1941 and 1944, and his skill as an administrator and a clinician...
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191917/the-last-apothecary-eric-knott-1896-1993-and-20th-century-pharmacy-in-scotland
#7
S L Goggins
Eric Knott was the last Apothecary at the Royal Public Dispensary and the last Principal of the Duncan School of Pharmacy. He linked pre-war apothecary practice to post-war chemist dispensing. This paper tracks his career from the Duncan School of Pharmacy, transfer to Heriot-Watt College in 1936, to the close of the Royal Public Dispensary in 1963, when the premises were transferred to the University of Edinburgh. It draws on unpublished archival material and long unseen collections from National Museums Scotland to explore what Knott's career can tell us about the impact of new legislation and the introduction of the NHS on pharmacy in Scotland...
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191916/it-must-be-true-%C3%A2-i-read-it-in-the-tabloids
#8
S Y Yip, D Namah, R Cook, C Isles
BACKGROUND: Previous attempts to improve the quality of health journalism have not led to more responsible reporting of health news. METHOD: We reviewed the front pages of three daily tabloid and three daily broadsheet UK newspapers during a 1 month period in 2017 for medical headlines in which claims were made for diets, lifestyle behaviours or drug therapies that influence health. RESULTS: Front page medical headlines were carried by the Daily Express (11), Daily Mail (two), Daily Mirror (one) and Daily Telegraph (one)...
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191915/penetrating-aortic-ulcer-causing-intramural-haematoma-presenting-as-pericarditis
#9
M Y Khanji, A S Sheikh, A Youhana, A Ionescu
No abstract text is available yet for this article.
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191914/cantos-is-selective-targeting-of-inflammation-in-atherosclerosis-enough
#10
D P Misra, V Agarwal
No abstract text is available yet for this article.
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191913/possible-modulation-of-concurrent-parkinson-s-disease-in-the-management-of-metastatic-gist-a-review-of-two-cases
#11
T Watson-Fargie, D G Grosset, J White, F Cowie
Imatinib, a tyrosine kinase inhibitor, is the mainstay of treatment for resected high-risk (adjuvant and metastatic) gastrointestinal stromal tumour (GIST) - a rare form of sarcoma. There has been recent research into the neuroprotective role and modulation of dopaminergic neurones by imatinib through the abl pathway in Parkinson's disease (PD). We describe two patients from a single cancer centre with concurrent diagnoses of PD and metastatic GIST receiving imatinib and standard PD management. The cases highlight a potential reduction in PD progression using Unified Parkinson's Disease Rating Scale...
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191912/successful-intravenous-thrombolysis-of-a-wake-up-stroke-with-underlying-valvular-atrial-fibrillation
#12
K K Shahedah, C S Khoo, W Y Wan Nur Nafisah, C F Ng, I Noor Ashikin, M Y Mohd Naim, O Syazarina Sharis, Z Rozman, W Z Wan Asyraf
A 42-year-old female admitted with new-onset atrial fibrillation had a wake-up stroke on the high-dependency unit and the time last seen well (TLSW) was 6.5 h. She suffered left-sided body weakness and her National Institutes of Health Stroke Scale (NIHSS) score was 17. An emergency CT perfusion showed right M1 segment occlusion with more than 50% penumbra. She was given recombinant tissue plasminogen activator (r-tPA) at 9 h from TLSW. An immediate diagnostic angiogram with intention to treat, owing to the presence of large vessel occlusion, showed complete reperfusion after intravenous r-tPA...
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191911/haemochromatosis-arthropathy-a-conundrum-of-the-celtic-curse
#13
P Dw Kiely
Genetic haemochromatosis is an autosomal recessive disorder, mostly due to HFE gene mutation, leading to loss of hepcidin and unregulated iron loading. The consequences include hepatic fibrosis, cardiomyopathy and skin pigmentation, and these sequelae along with fatigue may be prevented by 'de-ironing'. Joint pain is frequently reported at diagnosis and an arthropathy that is essentially accelerated osteoarthritis may develop, with onset at a younger than expected age, involvement of typical and atypical joints, such as metacarpophalangeal and ankle, exuberant osteophytes and rapid progression to cartilage loss and the need for arthroplasty...
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191910/cognitive-bias-in-clinical-medicine
#14
E D O'Sullivan, S J Schofield
Cognitive bias is increasingly recognised as an important source of medical error, and is both ubiquitous across clinical practice yet incompletely understood. This increasing awareness of bias has resulted in a surge in clinical and psychological research in the area and development of various 'debiasing strategies'. This paper describes the potential origins of bias based on 'dual process thinking', discusses and illustrates a number of the important biases that occur in clinical practice, and considers potential strategies that might be used to mitigate their effect...
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191909/the-key-challenges-of-discussing-end-of-life-stroke-care-with-patients-and-families-a-mixed-methods-electronic-survey-of-hospital-and-community-healthcare-professionals
#15
F Doubal, E Cowey, F Bailey, S A Murray, S Borthwick, M Somerville, C Lerpiniere, L Reid, K Boyd, G Hynd, G E Mead
BACKGROUND: Communication between professionals, patients and families about palliative and end-of-life care after stroke is complex and there is a need for educational resources in this area. METHODS: To explore the key learning needs of healthcare professionals, a multidisciplinary, expert group developed a short electronic survey with open and closed questions, and then distributed it to six UK multiprofessional networks and two groups of local clinicians. RESULTS: A total of 599 healthcare professionals responded...
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191908/does-dermatoscopy-facilitate-the-detection-and-diagnosis-of-vascular-skin-lesions-a-case-control-study
#16
A Chuh, V Zawar, G Sciallis
BACKGROUND: During dermatoscope-guided surgical procedures, we noticed that vasculature was easily identified. This study investigated the use of dermatoscopy in detecting and diagnosing vascular skin lesions. METHODS: We retrieved records of patients with vascular skin lesions who underwent dermatoscopy over a 3 month period, in two outpatient clinics affiliated with a university teaching hospital. Our controls were similar patients where dermatoscopy was not performed...
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191907/care-home-residents-admitted-to-hospital-through-the-emergency-pathway-characteristics-and-associations-with-inpatient-mortality
#17
V L Keevil, G J Martin, R Biram, S Wallis, R Romero-Ortuno
BACKGROUND: Routinely collected hospital information could help to understand the characteristics and outcomes of care home residents admitted to hospital as an emergency. METHODS: This retrospective 2-year service evaluation included first emergency admissions of any older adult (≥75 years) presenting to Cambridge University Hospital. Routinely collected patient variables were captured by an electronic patient record system. Care home status was established using an official register of care homes...
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191906/neurological-complications-in-patients-with-plasmodium-vivax-malaria-from-karachi-pakistan
#18
A Akhlaq, N K Ghanchi, B Usmani, R Shahzad, A Rahim, M Wasay, M A Beg
BACKGROUND: Malaria remains an endemic disease in Pakistan with an estimated healthcare burden of 1.6 million cases annually, with Plasmodium vivax accounting for 67% of reported cases. P. vivax is the most common species causing malaria outside of Africa, with approximately 13.8 million reported cases worldwide. METHOD: We report a series of P. vivax cases with cerebral involvement that presented at Aga Khan University Hospital, Karachi, Pakistan. RESULTS: The majority of the patients presented with high-grade fever accompanied by projectile vomiting and abnormal behaviour, seizures, shock and unconsciousness...
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/30191905/quality-governance-a-call-to-arms
#19
EDITORIAL
D Bell, M Deighan, P Gillen, L Rooke, K Small
No abstract text is available yet for this article.
September 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29992211/witnessing-history-a-personal-view-of-half-a-century-in-public-health
#20
B P Bergman, F Laing, A S Chandler, K C Calman
Former Chief Medical Officer Sir Kenneth Calman recently celebrated 50 years in medicine. It was a period which saw the evolution of the public health agenda from communicable diseases to diseases of lifestyle, the change from a hospital-orientated health service to one dominated by community-based services, and the increasing recognition of inequalities as a major determinant of health. This paper documents selected highlights from his career including the Aberdeen typhoid outbreak, AIDS, bovine spongiform encephalopathy, foot and mouth disease, radioactive fallout, the invention of computerised tomography and magnetic resonance imaging, and draws parallels between the development of the modern understanding of public health and the theoretical background to the science 100 years earlier...
June 2018: Journal of the Royal College of Physicians of Edinburgh
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