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Hormones: International Journal of Endocrinology and Metabolism

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https://www.readbyqxmd.com/read/30536046/reviews-based-on-the-17th-endorama-meeting
#1
EDITORIAL
Kostas B Markou, Neoklis Georgopoulos
No abstract text is available yet for this article.
December 7, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30519831/the-past-decade-in-type-2-diabetes-and-future-challenges
#2
REVIEW
Jihad A Haddad, Aiman N Haddad
There is today an exponential increase in prevalence of type 2 diabetes mellitus (T2DM), especially in young people. This downward shift in age of onset of T2DM has been shown by abundant evidence to be due to an increase in obesity among the young, the latter mainly attributable to unhealthy dietary habits and a sedentary lifestyle. It is therefore obvious that the prevention of diabetes rather its treatment is of is paramount importance. In the past decade, because concerns about the safety of antidiabetic agents took precedence over the issue of efficacy, almost all studies have been diabetes CVOTs and not traditional CVOTs...
December 5, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30515667/correction-to-unusual-presentation-of-recurrent-papillary-thyroid-microcarcinoma-with-neck-muscles-and-skin-dissemination
#3
Alessandro Sindoni, Carlo Gobitti, Sandro Sulfaro, Vittorio Giacomarra, Eugenio Borsatti
The original version of this article unfortunately contained a mistake. The title of this article was rendered incorrectly; the correct title is as follows: Unusual presentation of recurrent papillary thyroid microcarcinoma with neck muscles and skin dissemination.
December 4, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30515666/transsphenoidal-surgery-for-pituitary-adenomas-early-results-from-a-single-center
#4
I Karamouzis, M Caputo, C Mele, A Nuzzo, M Zavattaro, P Car, G Panzarasa, F Prodam, P Marzullo, Gianluca Aimaretti
OBJECTIVE: To evaluate early results of transsphenoidal surgery for pituitary adenomas. DESIGN: Retrospective evaluation of 90 consecutive patients undergoing endoscopic pituitary adenoma surgery (2007-2016) at "Maggiore della Carità" Hospital in Novara, Italy. Age at diagnosis, sex, symptoms at presentation, hormonal and radiological data, complications of surgery, and short-term follow-up information were collected. RESULTS: The majority of patients were male (M/F: 1...
December 4, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30511333/guidelines-for-exercise-during-normal-pregnancy-and-gestational-diabetes-a-review-of-international-recommendations
#5
Dimitra Savvaki, Eleftheria Taousani, Dimitrios G Goulis, Efrosini Tsirou, Evangelia Voziki, Helen Douda, Nikolaos Nikolettos, Savvas P Tokmakidis
OBJECTIVE: Τo summarize and present the main guidelines for exercise during normal pregnancy and pregnancy complicated by gestational diabetes mellitus (GDM). METHODS: Relevant guidelines were retrieved through the electronic databases PubMed (MEDLINE), CENTRAL (Cochrane), and Embase; reference sections of the retrieved publications; proceedings of the main congresses in the field; and websites of relevant organizations published during the years 2000-2018. RESULTS: All guidelines recommend aerobic training from 60 to 150 min/week, with an upper limit of 30 min/day...
December 3, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30484097/molecular-basis-of-vitamin-d-action-in-neurodegeneration-the-story-of-a-team-perspective
#6
REVIEW
Duygu Gezen-Ak, Erdinç Dursun
Vitamin D, a secosteroid hormone, has, over the years, mainly been known for its classic role in the maintenance of calcium homeostasis of the human body. However, there is increasing understanding that vitamin D contributes to the regulation of Ca2+ homeostasis, especially via voltage-gated calcium channels, in another major organ that uses calcium, the brain. Almost 30 years ago, the role of dysregulation in the aging brain and in Alzheimer's disease (AD) gave rise to the Ca2+ hypothesis of brain aging and dementia...
November 27, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30484096/vitamin-d-basis-of-alzheimer-s-disease-from-genetics-to-biomarkers
#7
REVIEW
Erdinç Dursun, Duygu Gezen-Ak
Alzheimer's disease (AD) is a progressive neurodegenerative disorder seen mostly in the elderly population. While to date AD research has focused on either neurochemical disruptions, genetic studies, or the pathological hallmarks, little has been done to establish a novel approach that would encompass all three aspects, one that would overcome the current barriers in AD research and determine the cause of AD and, eventually, discover a treatment. Meanwhile, there have been strong indications in recent years that vitamin D, a secosteroid hormone, and its receptors are fundamentally involved in neurodegenerative mechanisms...
November 27, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30471011/the-relationship-between-urotensin-ii-and-insulin-resistance-in-women-with-gestational-diabetes-mellitus
#8
Mehmet Calan, Tugba Arkan, Tuncay Kume, Fırat Bayraktar
AIM: Urotensin II (UII), a pluripotent vasoactive peptide, plays a crucial role in development of insulin resistance. Gestational diabetes mellitus (GDM) is a metabolic disorder associated with insulin resistance. The aims of the current study were to compare UII levels in women with or without GDM and to investigate the relationship between UII and insulin resistance in women with GDM. METHODS: A total of 84 women were recruited in this case-control study (42 women with GDM and 42 age- and body mass index (BMI)-matched pregnant women without GDM as controls)...
November 23, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30467685/noggin-levels-in-nonalcoholic-fatty-liver-disease-the-effect-of-vitamin-e-treatment
#9
Stergios A Polyzos, Jannis Kountouras, Athanasios D Anastasilakis, Polyzois Makras, Gerhard Hawa, Linda Sonnleitner, Albert Missbichler, Michael Doulberis, Panagiotis Katsinelos, Evangelos Terpos
AIM: The evaluation of (a) noggin levels in patients with simple steatosis (SS) vs. nonalcoholic steatohepatitis (NASH) vs. controls, and (b) the effect of combined spironolactone plus vitamin E vs. vitamin E monotherapy on noggin levels in biopsy-proven patients with nonalcoholic fatty liver disease (NAFLD). METHODS: In the case-control study, 15 patients with SS, 16 with NASH, and 24 controls were included. In the randomized controlled trial, NAFLD patients were assigned to vitamin E (400 IU/d) or spironolactone (25 mg/d) plus vitamin E for 52 weeks...
November 22, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30460459/precocious-or-early-puberty-in-patients-with-combined-pituitary-hormone-deficiency-due-to-pou1f1-gene-mutation-case-report-and-review-of-possible-mechanisms
#10
REVIEW
Firdevs Baş, Zehra Yavaş Abalı, Güven Toksoy, Şükran Poyrazoğlu, Rüveyde Bundak, Çağrı Güleç, Zehra Oya Uyguner, Feyza Darendeliler
Central precocious puberty (CPP) or early puberty (EP) is a rare entity in combined pituitary hormone deficiency (CPHD), the latter caused by mutations in pituitary transcription factor genes. The early onset of puberty in two patients with CPHD with POU1F1 gene mutation was evaluated. A 3-month-old boy was diagnosed with central hypothyroidism, and L-thyroxine was commenced. He was referred for the evaluation of short stature at 20 months of age. Anthropometric evaluation revealed severe short stature (- 6...
November 20, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30456751/an-update-on-adrenal-endocrinology-significant-discoveries-in-the-last-10-years-and-where-the-field-is-heading-in-the-next-decade
#11
REVIEW
Crystal D C Kamilaris, Constantine A Stratakis
The last 10 years have produced an amazing number of significant discoveries in the field of adrenal endocrinology. The development of the adrenal gland was linked to specific molecules. Cortisol-producing lesions were associated mostly with defects of the cyclic AMP (cAMP) signaling pathway, whereas aldosterone-producing lesions were found to be the result of defects in aldosterone biosynthesis or the potassium channel KCNJ5 and related molecules. Macronodular adrenal hyperplasia was linked to ARMC5 defects and new genes were found to be involved in adrenocortical cancer (ACC)...
November 19, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30456750/adiponectin-and-vitamin-d-binding-protein-concentrations-are-independently-associated-in-apparently-healthy-women-but-not-men-a-validation-cohort
#12
LETTER
Spyridon N Karras, Stergios A Polyzos, Xanthippi Tsekmekidou, Spyridon Gerou, Elpida Gavana, Vasileios Papageorgiou, Kalliopi Kotsa
No abstract text is available yet for this article.
November 19, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30430458/conducting-an-observational-study-during-an-economic-crisis-analysis-of-the-treatment-and-follow-up-phase-of-greek-patients-participating-in-the-exfos-study
#13
Kyriakos Aloumanis, G Kapetanos, T Alexandridis, V Drossinos, N Papaioannou
OBJECTIVE: We present the subanalysis of the Greek cohort of the Extended Forsteo Observational Study (ExFOS), a multicenter, non-interventional, prospective, observational study evaluating the effect of teriparatide on fractures, back pain (BP), health-related quality of life (HR-QoL), and safety and compliance, in patients with osteoporosis treated for up to 24 months, with a post-treatment follow-up of at least 18 months. DESIGN: A total of 439 osteoporotic patients (92...
November 14, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30421155/a-decade-in-female-reproduction-an-endocrine-view-of-the-past-and-into-the-future
#14
REVIEW
Djuro Macut, Danijela Vojnović Milutinović, Aleksandra Rašić-Marković, Jelena Nestorov, Jelica Bjekić-Macut, Olivera Stanojlović
Over the last decade, huge achievements have been made in the fields of neurophysiology, molecular endocrinology, and biochemistry, as well as in the successful translation of clinical research into diseases into clinical practice. As regards female reproduction, most of the advances made in this area were achieved in gonadal axis regulation, regulation of behavior through sex steroids, reproductive genetics, preservation of ovarian reproductive function, steroid profiling, and metabolic and overall reproductive outcomes...
November 12, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30415409/unusual-presentation-of-recurrent-papillary-thyroid-microcarcinoma-with-neck-muscle-and-skin-metastasis
#15
LETTER
Alessandro Sindoni, Carlo Gobitti, Sandro Sulfaro, Vittorio Giacomarra, Eugenio Borsatti
No abstract text is available yet for this article.
November 10, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30414080/socs3-as-a-future-target-to-treat-metabolic-disorders
#16
REVIEW
João A B Pedroso, Angela M Ramos-Lobo, Jose Donato
The suppressors of cytokine signaling (SOCS) are a group of eight proteins responsible for preventing excessive cytokine signaling. Among this protein family, SOCS3 has received special attention. SOCS3 expression is important to control certain allergy autoimmune diseases. Furthermore, SOCS3 expression is elevated in obesity and it is involved in the inhibition of leptin and insulin signaling, two important hormones involved in the control of energy metabolism. Therefore, increased SOCS3 expression in obese individuals is associated with several metabolic disorders, including reduced energy expenditure, increased food intake and adiposity, and insulin and leptin resistance...
November 9, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30368688/metabolic-syndrome-joint-diagnostic-criteria-and-links-with-comorbidities
#17
LETTER
Niki Katsiki, Michael Doumas, Vasilios Athyros
No abstract text is available yet for this article.
October 27, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30368687/medical-therapy-for-non-functioning-pituitary-tumors-a-critical-approach
#18
REVIEW
Metaxia Tampourlou, Olga Karapanou, Dimitra A Vassiliadi, Stylianos Tsagarakis
Non-functioning pituitary adenomas (NFPAs) are the second most common variant of pituitary tumors. When symptomatic, primary therapy is surgery. Recurrence rates are high. Since many NFPAs express dopamine and somatostatin receptors, medical therapy has been used after surgery in order to prevent recurrence. So far, dopamine agonists have been more widely tested with some promise when introduced immediately after surgery but with less efficacy when introduced later upon tumor regrowth. Currently, the role of medical therapy to prevent tumor regrowth in NFPAs is limited by imprecisions as to final outcome and uncertainties concerning on patient selection, dosing, duration, and side effects...
October 27, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30341577/prolactin-prolactin-disorders-and-dopamine-agonists-during-pregnancy
#19
REVIEW
Gabriel Levin, Amihai Rottenstreich
Pituitary disorders, and especially prolactinomas, are not common among pregnant women, though they tend to occur during a woman's years of fertility. The majority of prolactinoma patients present with infertility and menstruation dysfunction; however, prolactinomas are associated with potentially significant morbidity if they remain unrecognized and untreated. Herein, we survey the role of prolactin and prolactinomas in pregnancy while also outlining the therapeutic approach to prolactinoma during pregnancy...
October 19, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30317460/review-of-mobile-applications-for-optimizing-the-follow-up-care-of-patients-with-diabetes
#20
Nikolaos Th Ersotelos, Andrew N Margioris, Xu Zhang, Feng Dong
BACKGROUND: Several smartphone applications aim at facilitating communication between patients and healthcare providers. In this review, we evaluate and compare the most promising applications in the field of diabetes mellitus (DM) and obesity. Most applications monitor body weight, fasting or postprandial blood glucose, glycosylated hemoglobin (Hgb) A1c (HgbA1c), and units and types of insulin used. METHODS: Nine clinically tested applications and two Web platforms were grouped into three categories that were evaluated and compared...
October 13, 2018: Hormones: International Journal of Endocrinology and Metabolism
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