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European Surgery: ACA: Acta Chirurgica Austriaca

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https://www.readbyqxmd.com/read/29445392/how-many-parathyroid-glands-can-be-identified-during-thyroidectomy-evidence-based-data-for-medical-experts
#1
Elisabeth Gschwandtner, Rudolf Seemann, Claudia Bures, Lejla Preldzic, Eduard Szucsik, Michael Hermann
Background: The purpose of this study is to provide guidance for medical experts regarding malpractice claims on permanent hypoparathyroidism by analyzing the number of parathyroid glands (PGs) identified during thyroidectomy and the clinical outcome. Methods: Parathyroid findings were documented in a standardized protocol for 357 patients undergoing thyroidectomy and treated by a single specialized surgeon. The resected thyroid was routinely dissected for accidentally removed PGs with consecutive autotransplantation and the pathological report also described unintentionally resected PGs...
2018: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/29250106/update-on-the-management-of-barrett-s-esophagus-in-austria
#2
M Riegler, I Kristo, M Nikolic, E Rieder, S F Schoppmann
Background: Barrett's esophagus (BE) is the premalignant manifestation of gastroesophageal reflux disease (GERD). Radiofrequency ablation (RFA) with and without endoscopic resection (ER) is a novel treatment for BE. Methods: Here we present a single-center update of the recommendations of a recent (June 2015) interdisciplinary expert panel meeting on the management of BE with dysplasia as well as cancer-positive and cancer-negative BE. We conducted a PubMed search of studies published in 2016 and 2017 on the topic of BE and RFA...
2017: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/29250105/dietary-sugar-and-barrett-s-esophagus
#3
M Riegler, I Kristo, R Asari, E Rieder, S F Schoppmann
Introduction: Barrett's esophagus (BE) represents the premalignant morphology of gastroesophageal reflux disease (GERD). Evidence indicates a positive correlation between GERD vs. obesity and increased sugar consumption. Methods: Here we analyzed recently published data (2006-2017) on the role of dietary sugar intake for BE development (main focus year 2017). Results: Recent investigations found a positive association between obesity, hip waist ratio and dietary sugar intake and Barrett's esophagus...
2017: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/29104589/multimodality-locoregional-treatment-strategies-for-bridging-hcc-patients-before-liver-transplantation
#4
Georg P Györi, D Moritz Felsenreich, Gerd R Silberhumer, Thomas Soliman, Gabriela A Berlakovich
Background: It is current practice that patients with hepatocellular carcinoma (HCC) listed for liver transplantation should receive locoregional treatment if the suspected waiting time for transplantation is longer than 6 months, even in the absence of prospective randomized data. Aim of this study was the comparison of single versus multimodality locoregional treatment strategies on outcomes after liver transplantation. Methods: This is a retrospective analysis of 150 HCC patients listed for liver transplantation at our center between 2004 and 2011...
2017: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/29104588/preoperative-diagnosis-of-hiatal-hernia-barium-swallow-x-ray-high-resolution-manometry-or-endoscopy
#5
Michael Weitzendorfer, Gernot Köhler, Stavros A Antoniou, Leo Pallwein-Prettner, Lisa Manzenreiter, Philipp Schredl, Klaus Emmanuel, Oliver Owen Koch
Background: The assessment of hiatal hernias (HH) is typically done with barium swallow X‑ray, upper endoscopy, and by high-resolution esophageal manometry (HRM). The aim of this study was to assess the clinical utility of these methods in terms of HH detection and their correlation to gastroesophageal reflux disease (GERD). Methods: A retrospective comparative analysis of patients with symptoms of GERD was carried out. The performance of endoscopy and HRM in diagnosing HH was assessed, taking barium swallow X‑ray as a reference...
2017: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/29104587/notch-and-its-oncogenic-activity-in-human-malignancies
#6
REVIEW
Marlena Brzozowa-Zasada, Adam Piecuch, Marek Michalski, Oliwia Segiet, Józef Kurek, Marzena Harabin-Słowińska, Romuald Wojnicz
Background: Increasing evidence has demonstrated that Notch signaling is deregulated in human hematological malignancies and solid tumors. This signaling has a protumorigenic effect but may also act as a tumor suppressor. How induction of a single pathway gives rise to the opposite effects in different cell types is still unknown. Methods: This review article includes available data from peer-reviewed publications associated with the role of Notch signaling during cancer pathogenesis...
2017: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/28596786/impact-of-ultrasound-examination-shortly-after-kidney-transplantation
#7
Christoph Schwarz, Jakob Mühlbacher, Georg A Böhmig, Marin Purtic, Eleonore Pablik, Lukas Unger, Ivan Kristo, Thomas Soliman, Gabriela A Berlakovich
BACKGROUND: Ultrasound is routinely performed at our transplant unit within the first 48 h of kidney transplantation (KTX). The objective of this study was to evaluate the association of ultrasound results and, in particular, elevated resistance indices (RIs) with the occurrence of surgical complications and allograft outcomes. METHODS: The study included all kidney allograft recipients undergoing transplantation at our center between January 2010 and December 2011 (N = 329)...
2017: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/28596785/oxidative-stress-and-angiogenesis-in-primary-hyperparathyroidism
#8
Mariusz Deska, Ewa Romuk, Oliwia Anna Segiet, Grzegorz Buła, Witold Truchanowski, Dominika Stolecka, Ewa Birkner, Jacek Gawrychowski
BACKGROUND: The inappropriate elevation of parathormone (PTH), which regulates the process of angiogenesis in parathyroid tissue, causes the changes of activity of enzymes responsible for the removal of free radicals. Parathyroidectomy (PTX) in patients with primary hyperparathyroidism (PHPT) lowers the level of PTH and leads to the reduction of risk of cardiovascular and all-cause mortality by normalization of the antioxidant status. Therefore, the aims of the study were to assess the activity of antioxidant enzymes and free radical reaction products in patients after parathyroidectomy, and to evaluate the correlation between the systemic oxidative stress and angiogenic parameters...
2017: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/28408920/endoscopic-assisted-linea-alba-reconstruction-new-technique-for-treatment-of-symptomatic-umbilical-trocar-and-or-epigastric-hernias-with-concomitant-rectus-abdominis-diastasis
#9
Ferdinand Köckerling, Marinos Damianos Botsinis, Christine Rohde, Wolfgang Reinpold, Christine Schug-Pass
BACKGROUND: Patients with symptomatic umbilical, trocar, and/or epigastric hernias and concomitant rectus abdominis diastasis represent a growing clinical problem. The optimal management of this complex hernia situation is the subject of debate in the literature. This paper reports the early results of an innovative surgical technique aimed at managing this hernia situation. METHODS: Endoscopic-assisted linea alba reconstruction (ELAR) with mesh augmentation is a surgical technique long known in the literature for its good outcome for incisional hernia repair (myofascial release, overlapping herniorrhaphy, Gibson's operation, shoelace repair, anterior rectus sheath repair, dynamic patch plasty) via a small access route...
2017: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/28191012/application-of-modified-small-bladder-patch-to-bladder-double-layer-sutures-to-improve-renal-transplantation-in-mice
#10
Chen Wenwei, Yang Yirong, Katarzyna M Stevens, Michal Heger, Xia Peng
BACKGROUND: This study aimed to introduce an improved surgical procedure to reduce the incidence of urinary tract complications after renal transplantation in mice using a modified bladder patch-to-bladder anastomosis technique. METHODS: Renal isotransplantation was performed in 28 male C57BL/6 mice. The urinary tract was reconstructed with a ureteral anastomosis between the donor's small bladder patch and the recipient's bladder. The bladder patch was secured through a cystotomy in the recipient's bladder mucosa and seromuscular layers, which were sutured in a double-layer manner...
2017: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/29142584/viability-of-five-different-pre-and-intraoperative-imaging-methods-for-autologous-breast-reconstruction
#11
K F Schrögendorfer, S Nickl, M Keck, D B Lumenta, C Loewe, M Gschwandtner, W Haslik, J Nedomansky
Background: Autologous breast reconstruction is an integral part in the treatment of breast cancer. While computed tomography angiography (CTA) is an established preoperative diagnostic tool for microsurgeons, no study has so far evaluated and compared five different imaging methods and their value for the reconstructive team. In order to determine the feasibility of each of the tools for routine or specialized diagnostic application, the methods' efficiency and informative value were analyzed...
2016: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/28058043/programmed-death-ligand-1-expression-in-rectal-cancer
#12
G Jomrich, G R Silberhumer, B Marian, A Beer, L Müllauer
BACKGROUND: Colorectal cancer (CRC) is the fourth most common cause of death worldwide. Approximately 30 % of all CRC occurs in the rectum. Improvements in survival rates were achieved thanks to multimodal therapy, combining surgery and chemoradiation. Nevertheless, the prognosis of patients suffering from rectal cancer (RC) remains poor. Programmed cell death protein 1 (PD-1) and its ligand programmed death ligand 1 (PD-L1) regulate tumor immune response. The aim of this study was to analyze the expression of PD-L1 in RC pre- and post-neoadjuvant therapy and evaluate PD-L1 as a biomarker and potential target for therapy...
2016: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/28058042/experimental-nerve-transfer-model-in-the-rat-forelimb
#13
K D Bergmeister, M Aman, O Riedl, K Manzano-Szalai, M E Sporer, S Salminger, O C Aszmann
BACKGROUND: Nerve transfers are a powerful tool in extremity reconstruction, but the neurophysiological effects have not been adequately investigated. As 81 % of nerve injuries and most nerve transfers occur in the upper extremity with its own neurophysiological properties, the standard rat hindlimb model may not be optimal in this paradigm. Here we present an experimental rat forelimb model to investigate nerve transfers. METHODS: In ten male Sprague-Dawley rats, the ulnar nerve was transferred to the motor branch of long head of the biceps...
2016: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/27795701/targeted-therapy-in-gastric-cancer
#14
G Jomrich, S F Schoppmann
BACKGROUND: Gastric cancer is the fourth most common cancer worldwide. Surgery in combination with multimodal therapy provides the only curative therapy until now. The importance of targeted therapy became clear over the last few years. Due to the implication of HER2 and angiogenesis-directed targeted therapies major advances in the treatment of gastric cancer could be reached. Nevertheless, benefits in survival remain unsatisfactory and the development of resistance to monoclonal antibodies is arising...
2016: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/27398082/facial-reconstruction-with-a-unique-osteomyocutaneous-dcia-perforator-flap-variant-a-case-report
#15
G Wechselberger, K Schwaiger, J Hachleitner, G Oberascher, F Ensat, L Larcher
BACKGROUND: Anatomical variance of the deep circumflex iliac artery is of high clinical value in facial reconstruction using a deep circumflex iliac artery perforator (DCIAP) flap. METHODS: We present the case of a 76-year-old woman treated with an osteomyocutaneous DCIAP flap variant for facial reconstruction. We also review here the literature on DCIA perforator flaps and the different anatomical variances, which might bring clinical benefits. RESULTS: The observed anatomy in our patient offered the possibility to raise a free flap variant with high mobility of a large skin paddle and a long vascular pedicle combined with a variable osteomuscular portion...
2016: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/27340394/leadership-and-training
#16
D Öfner
Against the background of substantial changes in the field of healthcare in Austria, the specialization in surgery must be reconsidered starting from modified points of view. However, in this context, the new training regulations are not the only standard: the training officers must show leadership skills by paying attention to the modified framework conditions and by promoting a new corporate culture related to training with innovating concepts. The challenge of the threatening quality loss in surgery can only be addressed in this way...
2016: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/27110233/ischemia-reperfusion-facilitated-sinusoidal-endothelial-cell-injury-in-liver-transplantation-and-the-resulting-impact-of-extravasated-platelet-aggregation
#17
T Miyashita, S Nakanuma, A K Ahmed, I Makino, H Hayashi, K Oyama, H Nakagawara, H Tajima, H Takamura, I Ninomiya, S Fushida, J W Harmon, T Ohta
BACKGROUND: The exact sequence of events leading to ultimate hepatocellular damage following ischemia/reperfusion (I/R) is incompletely understood. In this article, we review a mechanism of organ dysfunction after hepatic I/R or immunosuppressive treatment, in addition to the potential of liver sinusoidal endothelial cell (LSEC) protection and antiplatelet treatment for the suppression of hepatocellular damage. METHODS: A review of the literature, utilizing PubMed-NCBI, was used to provide information on the components necessary for the development of hepatocellular damage following I/R...
2016: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/26566387/the-knowledge-of-polish-medical-students-about-surgical-treatment-of-obesity
#18
M Matłok, M Pędziwiatr, P Major, M Nowakowski, M Rubinkiewicz, M Wyleżoł, P Budzyński, A Budzyński
BACKGROUND: Surgical treatment of morbid obesity is becoming an increasingly important approach for the treatment of this condition. However, knowledge about the possibility of surgical procedures among general practitioners is far from satisfactory. The source of the problem might be due to a lack of information about bariatric surgery in university curriculum. METHODS: We assessed the knowledge of students from four Polish medical universities. The survey was conducted among 468 students, in their sixth (final) year of study...
2015: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/25400659/the-effects-of-sleeve-gastrectomy-on-hormonal-regulation-of-glucose-metabolism-in-goto-kakizaki-rats
#19
Z Zhu, X Yang, K Wang, Z Wang, Y Zhao, M Yu
BACKGROUND: The antidiabetic effect of sleeve gastrectomy (SG) has been interpreted as a conceivable result of surgically induced weight loss in the obese type 2 diabetes mellitus (T2DM) subjects. However, the blood glucose control often occurs within days, before significant weight loss has been reached. This work aims to investigate the major mechanism and persistence regarding how SG improves glucose metabolism in nonobese T2DM rats. METHODS: These Goto Kakizaki rats (n = 21) were randomly assigned into three groups: SG, sham SG, and pair-fed (PF) group, whose weight, food intake, oral glucose tolerance test, insulin tolerance test, plasma insulin, homeostasis model assessment for insulin resistance (HOMA-IR), ghrelin, and glucagon-like peptide-1 (GLP-1) were measured...
2014: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/24971087/short-hospital-stays-after-laparoscopic-gastric-surgery-under-an-enhanced-recovery-after-surgery-eras-pathway-experience-at-a-single-center
#20
M Pędziwiatr, M Matłok, M Kisialeuski, M Migaczewski, P Major, M Winiarski, P Budzyński, A Zub-Pokrowiecka, A Budzyński
INTRODUCTION: Recently, first reports on benefits from Enhanced Recovery After Surgery (ERAS) pathway in patients undergoing gastric surgery have appeared. It seems that maximal reduction of unfavorable surgery-induced trauma in patients with gastric malignancy via ERAS protocol combined with minimally invasive techniques can improve outcomes. OBJECTIVE: The aim of this study was to determine the influence of laparoscopic surgery and ERAS protocol in oncological gastric surgery on early outcomes...
2014: European Surgery: ACA: Acta Chirurgica Austriaca
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