Ya Fu, Liang Zhang, Shupei Qin, Meng Tang, Yanxia Hao, Xuedong Chen, Yan Wang, Ting Zhou, Yuemei Xue, Long Cheng, Na Liu, Qifeng Jia, Yangyang Chen, Li Li
BACKGROUND: Rapamycin is known to induce autophagy, promote cell survival and inhibit the progression of diabetic nephropathy (DN). OBJECTIVES: The aim of this study was to examine the role of autophagy in the treatment of DN with rapamycin to provide the basis for the DN treatment with rapamycin. MATERIAL AND METHODS: Human mesangial cells (HMC) were cultured in a constant temperature incubator with 5% CO2, at 37°C and saturated humidity...
February 6, 2024: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University