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Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University

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https://www.readbyqxmd.com/read/28691432/effect-of-diode-lasers-with-wavelength-of-445-and-980-nm-on-a-temperature-rise-when-uncovering-implants-for-second-stage-surgery-an-ex-vivo-study-in-pigs
#1
Jacek Matys, Rafał Flieger, Marzena Dominiak
BACKGROUND: Many surgical procedures in a soft tissue are performed using diodes lasers. Recently, a novel diode laser operates in 445 nm wavelength was introduced in dentistry. OBJECTIVES: The aim of our study was to evaluate a time of surgery and an increase in temperature of a titanium implants during its uncovering using 445 and 980 nm wavelengths. MATERIAL AND METHODS: The research included 45 pig mandibles (n=45). The specimens were randomly divided into 3 groups (n=15) according to the laser irradiation mode and wavelength; G1 - 445nm laser, power: 3 W, continuous wave (CW), distance: 2 mm, power density: 7460 W/cm2, fiber: 320µm, none-contact mode; G2 - 445nm laser (power: 2 W, CW, power density: 4970 W/cm2, fiber: 320µm, contact mode; G3 (control) - 980nm laser, power: 2...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691431/low-dose-computed-tomography-in-assessment-of-pulmonary-abnormalities-in-children-with-febrile-neutropenia-suffering-from-malignant-diseases
#2
Urszula Zaleska-Dorobisz, Cyprian Michal Olchowy, Mateusz Łasecki, Dąbrówka Sokołowska-Dąbek, Aleksander Pawluś, Jowita Frączkiewicz, Ewa Gorczyńska
BACKGROUND: Management of febrile neutropenia in pediatric patients is challenging. Chest X-ray and CT help to identify infective foci; however, exposure to radiation is a risk factor for development of secondary cancer. For this reason, attention is paid to reduce radiation exposure. OBJECTIVES: TTo define the role of LDCT examination in early detection of pulmonary lesions in children during oncology or autoimmune treatment complicated by neutropenia related fever...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691430/the-mechanical-properties-of-human-dentin-for-3-d-finite-element-modeling-numerical-and-analytical-evaluation
#3
Wojciech Grzebieluch, Będziński Romuald, Czapliński Tomasz, Urszula Kaczmarek
BACKGROUND: The FEM is often used in investigations of dentin loading conditions; however, its anisotropy is mostly neglected. OBJECTIVES: The purpose of the study was to evaluate the anisotropy and the elastic properties of an equivalent homogenous material model of human dentin as well as to compare isotropic and anisotropic dentin FE-models. MATERIAL AND METHODS: Analytical and numerical dentin homogenization according Luciano and Barbero was performed and E-modulus (E), Poisson's ratios (v) G-modulus (G) were calculated...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691429/effectiveness-of-bariatric-procedures-based-on-selected-laboratory-parameters-of-patients-from-rural-areas-in-polish-population
#4
Regina Sierżantowicz, Jolanta Lewko, Lech Trochimowicz, Bożena Kirpsza, Jacek Dadan, Hady Razak Hady
BACKGROUND: The latter are inhabited by over 15 million people, i.e. 39.5% of Polish population, including about 5 million rural residents in the Podlaskie voivodeship. The incidence of obesity is associated with increased prevalence of obesity-related conditions. The conducted studies do not confirm the efficacy of conservative treatment obesity, but show that bariatric procedures produce the best long-term results. OBJECTIVES: The aim of the study was to present the effects of bariatric obesity treatment (LAGB, SG, RYGB) on body mass index (BMI), selected diabetes control parameters, dyslipidemia, hepatic and renal enzymes, blood count, and hypertension control...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691428/stat-proteins-as-intracellular-regulators-of-resistance-to-myocardial-injury-in-context-of-cardiac-remodeling-and-targeting-for-therapy
#5
REVIEW
Andrzej Wincewicz, Stanislaw Sulkowski
Roles of STAT (signal transducers and activators of transcription) proteins are widely discussed in relation to other agents like IFN-γ that are involved in cardiovascular diseases. STAT3 protects cardiomyocytes during endotoxic shock and ischemia and prolongs survival of these cells by activation of antiapoptotic genes like bcl-2 and c-fos. Moreover, IL-6 dependent expression of STAT3 probably is responsible for hypertrophy of cardiomyocytes. On the contrary STAT1 mediates cell death by induction of caspase-1...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691427/pancreatic-duct-stones-a-report-of-16-cases
#6
Magdalena Panek-Jeziorna, Jarosław Wierzbicki, Abdulhabib Annabhani, Leszek Paradowski, Agata Mulak
BACKGROUND: Pancreatolithiasis occurs in less than 1% of the general population and is mainly recognized in patients with chronic pancreatitis. Selection of the appropriate treatment method depends on location, size and number of stones. OBJECTIVES: The aim of the study was to analyze the data concerning patients with pancreatic duct stones who were hospitalized in the Department of Gastroenterology and Hepatology in years 2010-2014. MATERIAL AND METHODS: The study presents the data on 16 patients with pancreatic duct stones that constituted 7% of all 228 patients with chronic pancreatitis hospitalized in the Department in that period...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691426/physical-activity-related-changes-in-adma-and-vwf-levels-in-patients-with-type-2-diabetes-a-preliminary-study
#7
Zanna Fiodorenko-Dumas, Ilias Dumas, Krzysztof Mastej, Rajmund Adamiec
BACKGROUND: The activity and the role of methylarginine in diabetic patients are subject to continuous research. The mechanism through which diabetes or insulin resistance increases asymmetric dimethylarginine (ADMA) serum levels is not fully understood.Studies indicate increased ADMA serum levels in patients with hypertension, hypercholesterolemia and hyperhomocysteinemia. OBJECTIVES: The aim of the study was to assess changes in the levels of ADMA and its derivatives related to the current disease process, as well as the levels of selected prothrombotic factors and their changes induced by physical activity...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691425/tolerance-of-combined-radiochemotherapy-in-cervical-cancer-patients
#8
Barbara Izmajłowicz, Małgorzata Rusiecka, Aleksandra Sztuder, Marcin Stępień, Agnieszka Ignatowicz- Pacyna, Beata Słocka- Romaniuk, Zbigniew Mazur, Jan Kornafel
BACKGROUND: Radiochemotherapy in cervical cancer was implemented to clinical practice based on five randomized clinical trials, published at the end of 20th century, which showed improvement in total and symptomless survivals by about 10 to 18 %. The increase of therapeutic index of such treatment can take place only at the advantage of the efficiency over the increase of its toxicity. Thus, it is necessary to monitor treatment reaction during radiochemotherapy. OBJECTIVES: The aim of this study is to assess the acute post-radiation reaction during radiochemotherapy for cervical cancer and the analysis of the reasons of the unplanned course of combined treatment...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691424/an-animal-model-of-the-procognitive-properties-of-cysteine-protease-inhibitor-and-immunomodulatory-peptides-based-on-colostrum
#9
Bartłomiej Stańczykiewicz, Marta Jakubik-Witkowska, Antoni Polanowski, Tadeusz Trziszka, Joanna Rymaszewska
BACKGROUND: The positive effect of human cystatin C on the development of Alzheimer's disease has been reported, as it inhibits the formation of β-amyloid oligomers and amyloidogenesis. Cystatin C has been found to have a neuroprotective effect through inhibiting cysteine proteases, inducing autophagy and neurogenesis. There is a growing interest in the procognitive properties of colostrum-based specimens, which could delay dementia and ameliorate memory deterioration. OBJECTIVES: The aim of the study was to evaluate the influence of Ovocystatin and a Coloco peptide complex on the cognitive functions in reference to Colostrinin, using a model of young and old rats...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691423/the-magnitude-of-weight-loss-induced-by-metformin-is-independently-associated-with-bmi-at-baseline-in-newly-diagnosed-type-2-diabetes-post-hoc-analysis-from-data-of-a-phase-iv-open-labeled-trial
#10
Lingli Zhou, Xiaoling Cai, Wenjia Yang, Xueyao Han, Linong Ji
BACKGROUND: The impact of metformin on body weight is variable in T2DM patients among studies. The reasons for discrepancies are still unknown. OBJECTIVES: We aimed to find out the possible predictive factors of weight change induced by metformin based on an analysis of a phase IV open-labeled trial. MATERIAL AND METHODS: We performed a sub-analysis from a prospective, multi-center, Phase IV open-labeled study in which 371 Chinese newly diagnosed type 2 diabetes patients received 16 weeks' extended-release metformin monotherapy...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691422/hepatitis-e-virus-antibodies-in-hiv-infected-patients-and-blood-donors-from-western-poland-a-preliminary-report
#11
Maciej Bura, Alicja Bukowska, Aleksandra Bura, Michał Michalak, Iwona Mozer-Lisewska
BACKGROUND: Hepatitis E virus (HEV) infection is an emerging problem in industrialized countries, including Europe. A few data exist on HEV seroprevalence in Poland. OBJECTIVES: The aim of this study was to assess the prevalence of anti-HEV IgG antibodies in Polish patients infected with human immunodeficiency virus (HIV) and blood donors. MATERIAL AND METHODS: Two hundred and ten individuals (n=105 of HIV-infected patients and n=105 of ageand sex-matched blood donors from the same area; 178 men and 32 women), aged 18-50 (median age: 38 years), were tested for the presence of anti-HEV IgG antibodies with the EUROIMMUN Anti-Hepatitis E Virus (HEV) ELISA (IgG) tests (Luebeck, Germany)...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691421/effects-of-long-and-short-term-darbepoetin-%C3%AE-treatment-on-oxidative-stress-inflammation-and-endothelial-injury-in-apo-e-knockout-mice
#12
Evrim Dursun Özdemir, Aysegul Hanikoglu, Aysegul Cort, Beste Ozben, Gultekin Suleymanlar, Tomris Ozben
BACKGROUND: Atherosclerosis and atherosclerosis related complications are the main cause of death in the world. Vascular injury in response to inflammation, enhanced oxidant stress promotes endothelial dysfunction and leads to atherosclerotic lesions. OBJECTIVES: Low-dose treatment with Darbepoetin-α may be a potential therapeutic tool for endothelial injury and atherosclerosis. MATERIAL AND METHODS: In order to study the effect of Darbepoetin-α on endothelial injury and atherosclerosis, we used Apo E-/- mice as the atherosclerotic mice model...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691420/recent-advances-in-tissue-conditioners-for-prosthetic-treatment-a-review
#13
REVIEW
Barbara Dorocka-Bobkowska, Dominik Medynski, Mariusz Prylinski
Tissue conditioners (TCs) are short term soft liners, formed in situ from the mixture of a polymer powder and a liquid plasticizer. The article reviews recent advances in composition, functions, clinical use, gelation process, and physical properties of TCs and their effects on denture bases and oral mucosa. TCs are used to improve the fit and function of an ill-fitting denture. They can also be used to treat abused mucosal tissues underlying ill-fitting acrylic dentures as temporary expedients. TCs are recommended as provisional liners to maintain the fit of removable dentures and to prevent mechanical irritation from the denture...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691419/circulating-pcsk9-over-srebp-2-expression-affects-serum-ldl-and-cholesterol-levels
#14
Asghar Mohammadi, Mohamad Shabani, Faezeh Naseri, Bita Hosseni, Elham Soltanmohammadi, Sadegh Piran, Mohammad Najafi
BACKGROUND: Cholesterol homeostasis is dependent upon sterol regulation element binding protein2 (SREBP-2) regulatory system and plasma proprotein convertase subtilin/kexin type 9 (PCSK9) function. Furthermore, many studies have reported that cellular membrane LDLR level is related to the function of these proteins. OBJECTIVES: The aim of this study was to investigate the association of lipid profile with circulating PCSK9 protein value and SREBP-2 expression level in normal subjects...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691418/associations-between-the-number-of-natural-teeth-and-the-maternal-age-at-childbirth-or-history-of-parity-in-postmenopausal-women-the-2010-2012-korea-national-health-and-nutrition-examination-survey
#15
Kyungdo Han, Insoo Kim, Yong-Gyu Park, Jun-Beom Park
BACKGROUND: The relationship between reproductive factors, including pregnancy and delivery in postmenopausal women, and the number of teeth remains to be revealed. OBJECTIVES: This study evaluated the relationship between childbearing age (age at first and last delivery), parity and the number of natural teeth in postmenopausal women using nationally representative data. MATERIAL AND METHODS: The data from the Korea National Health and Nutrition Examination Survey between 2010 and 2012 were used, and the analysis in this study was confined to a total of 4,060 respondents over 19 years old who had gone through menopause and had no missing values for the reproductive factors and outcome variables...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691417/effect-of-endovascular-coronary-low-level-laser-therapy-during-angioplasty-on-the-release-of-endothelin-1-and-nitric-oxide
#16
Arkadiusz Derkacz, Alicja Szymczyszyn, Ewa Szahidewicz-Krupska, Marcin Protasiewicz, Rafał Poręba, Adrian Doroszko
BACKGROUND: NO and endothelin-1 are potentially significant factors contributing to the pathogenesis of post-angioplasty restenosis. It may be postulated that LLLT can favourably influence the process of restenosis by affecting those factors. OBJECTIVES: The aim of the study was to evaluate the effect of low-level laser therapy (LLLT) applied during percutaneous coronary intervention (PCI) on the factors participating in the homeostasis of vascular tone - nitric oxide (NO) and endothelin-1...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691416/the-relationship-between-major-depressive-disorders-and-glucose-parameters-a-cross-sectional-study-in-chinese-population
#17
You-Fan Peng, Shi-Mao Zhong, Qin Yu-Hua, Xu Hui-Dan, Wei Wu-Jun
BACKGROUND: Depressive symptoms have been linked with insulin resistance in middle-aged and elderly population. A strong relationship between peripheral insulin resistance and glucose homeostasis imbalance has well been established in previous study. The role of serum fructosamine and fasting blood glucose (FBG) for the elevation in glucose homeostasis has been documented in the literature. OBJECTIVES: We examined the association of serum fructosamine , FBG with major depressive disorders (MDD)...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691415/association-of-ace-vegf-and-ccl2-gene-polymorphisms-with-henoch-schonlein-purpura-and-evaluating-the-possible-interaction-effects-of-these-loci-in-hsp-patients
#18
Tahereh Mohammadian, Mortaza Bonyadi, Elahe Nabat, Mandana Rafeey
BACKGROUND: Henoch-Schonlein purpura (HSP) is a multisystem, small vessel, leucocytoclastic vasculitis. It is predominantly a childhood vasculitis, rarely reported in adults. Studies have shown that several different genetic factors such as genes involved in inflammatory system and renin-angiotensin system (RAS) are important in the pathogenesis of Henoch-Schönlein purpura. OBJECTIVES: The purpose of this study was to evaluate the independent effect of three gene polymorphisms including CCL2-2518 C/T, VEGF-634G/C and ACE(I/D) with HSP disease and their possible joint interactions in developing the disease...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691414/serum-levels-of-vascular-endothelial-growth-factor-vegf-and-basic-fibroblast-growth-factor-bfgf-in-children-with-brain-tumours
#19
Grażyna Sobol-Milejska, Agnieszka Mizia-Malarz, Katarzyna Musiol, Jerzy Chudek, Maria Bożentowicz-Wikarek, Halina Wos, Marek Mandera
BACKGROUND: Angiogenesis is a process of new vessel formation originating from the already present vascular network. It plays an important role in the growth and spreading of malignancies, including brain tumours. Process of angiogenesis is characterised by increased expression of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), and release of their soluble forms into circulation. OBJECTIVES: The aim of the study was to evaluate serum levels of VEGF and bFGF in children with malignant and benign brain tumours...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691413/diagnostic-challenges-in-celiac-disease
#20
REVIEW
Karol Kowalski, Agata Mulak, Maria Jasińska, Leszek Paradowski
Diagnosis of celiac disease in adults is currently based on serologic tests in combination with histopathological assessment of small intestinal biopsy specimens. High titers of celiac-specific antibodies in immunocompetent patients with villous atrophy in a good quality biopsy sample allow to state confident diagnosis. Relive of symptoms and histological improvement after embarking on a gluten free diet further support initial diagnosis. However, in some cases, these conditions are not fulfilled what requires critical evaluation of laboratory and histopathology results and consideration of other potential causes for observed pathologies...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
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