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Circulation Journal: Official Journal of the Japanese Circulation Society

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https://www.readbyqxmd.com/read/30643107/oral-%C3%AE-blocker-therapy-in-acute-myocardial-infarction
#1
Neiko Ozasa, Takeshi Kimura
No abstract text is available yet for this article.
January 12, 2019: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30643106/clinical-and-electrocardiographic-differences-in-brugada-syndrome-with-spontaneous-or-drug-induced-type-1-electrocardiogram
#2
Tomomi Nagayama, Satoshi Nagase, Tsukasa Kamakura, Mitsuru Wada, Kohei Ishibashi, Yuko Y Inoue, Koji Miyamoto, Takashi Noda, Takeshi Aiba, Hiroshi Takaki, Masaru Sugimachi, Wataru Shimizu, Teruo Noguchi, Satoshi Yasuda, Shiro Kamakura, Kengo Kusano
BACKGROUND: Spontaneous type 1 electrocardiogram (ECG) in the right precordial lead is a dominant predictor of ventricular fibrillation (VF) in Brugada syndrome (BrS). In some BrS patients with VF, however, spontaneous type 1 ECG is undetectable, even in repeated ECG and immediately after VF. This study investigated differences between BrS patients with spontaneous or drug-induced type 1 ECG. Methods and Results: We evaluated 15 BrS patients with drug-induced (D-BrS) and 29 with spontaneous type 1 ECG (SP-BrS)...
January 12, 2019: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30643080/prevalence-and-incidence-of-atrial-fibrillation-in-the-general-population-based-on-national-health-insurance-special-health-checkups-tama-med-project-af
#3
Eitaro Kodani, Tomohiro Kaneko, Hitomi Fujii, Hiroyuki Nakamura, Hajime Sasabe, Yutaka Tamura, Wataru Shimizu
BACKGROUND: Although National Health Insurance special health checkups have been useful for the diagnosis of metabolic syndrome, they are insufficient to identify atrial fibrillation (AF). In Tama City in Tokyo, 12-lead electrocardiogram has been included as an essential examination in special health checkups to diagnose AF since 2008. Methods and Results: In subjects aged 40-74 years at entry, prevalence of AF was 0.8% (men, 1.7%; women, 0.2%) in 2008 and 1.4% (men, 2.9%; women, 0...
January 11, 2019: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30643079/dual-anti-thrombotic-therapy-with-dabigatran-after-percutaneous-coronary-intervention-in-atrial-fibrillation-japanese-and-east-asian-subgroup-analysis-of-the-re-dual-pci-trial
#4
Junya Ako, Ken Okumura, Koichi Nakao, Ken Kozuma, Yoshihiro Morino, Kotaro Okazaki, Taku Fukaya, Takeshi Kimura
BACKGROUND: In the RE-DUAL PCI trial, dual anti-thrombotic therapy with dabigatran and a P2Y12 inhibitor had a lower risk of bleeding and similar risk reduction of thromboembolic events, compared with warfarin triple therapy, in patients with NVAF undergoing PCI. This subanalysis investigated whether the efficacy and safety of dabigatran dual therapy in Japanese and East-Asian patients enrolled in the RE-DUAL PCI trial were similar to those of the overall patient population of the trial...
January 11, 2019: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30626763/trends-and-outcome-of-catheter-ablation-of-atrial-fibrillation-over-9-years-focus-on-empirical-extra-pulmonary-vein-ablation
#5
Je-Wook Park, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak
BACKGROUND: The Substrate and Trigger Ablation for Reduction of Atrial Fibrillation Trial Part II (STAR-AF2) emphasized the importance of circumferential pulmonary vein isolation (CPVI) during AF ablation. Methods and Results: This study involved 2,297 consecutive patients (mean age, 58±11 years; 73.1% male, 70.1% paroxysmal AF) undergoing AF ablation from 2009 to 2017. We investigated the ablation lesion set, ablation time, catheter type, and clinical outcomes. Over the 9 years, the extra-pulmonary vein (PV) left atrial (LA) ablation rate (76...
January 9, 2019: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30606944/unexpected-but-reasonable-association-between-anderson-fabry-disease-and-coronary-vasospasm
#6
Tetsuya Matoba, Yasuhiro Nakano, Hiroyuki Tsutsui
No abstract text is available yet for this article.
December 29, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30606943/controversies-in-the-2017-acc-aha-hypertension-guidelines-who-can-be-eligible-for-treatments-under-the-new-guidelines-an-asian-perspective
#7
Sang-Hyun Ihm, George Bakris, Ichiro Sakuma, Il Suk Sohn, Kwang Kon Koh
Until the 2017 ACC/AHA Hypertension Guidelines were released, the target blood pressure (BP) for adults with hypertension (HTN) was 140/90 mmHg in most of the guidelines. The new 2018 ESC/ESH, Canadian, Korean, Japan, and Latin American hypertension guidelines have maintained the <140/90 mmHg for the primary target in the general population and encourage reduction to <130/80 if higher risk. This is more in keeping with the 2018 American Diabetes Association guidelines. However, the 2017 ACC/AHA guidelines classify HTN as BP ≥130/80 mmHg and generally recommend target BP levels below 130/80 mmHg for hypertensive patients independently of comorbid disease or age...
December 29, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30606942/ivabradine-for-the-treatment-of-cardiovascular-diseases
#8
Tomomi Ide, Kisho Ohtani, Taiki Higo, Makoto Tanaka, Yasushi Kawasaki, Hiroyuki Tsutsui
Higher heart rate (HR) is independently related to worse outcomes in various cardiac diseases, including hypertension, coronary artery disease, and heart failure (HF). HR is determined by the pacemaker activity of cells within the sinoatrial node. The hyperpolarization-activated cyclic nucleotide-gated (HCN) 4 channel, one of 4 HCN isoforms, generates the If current and plays an important role in the regulation of pacemaker activity in the sinoatrial node. Ivabradine is a novel and only available HCN inhibitor, which can reduce HR and has been approved for stable angina and chronic HF in many countries other than Japan...
December 29, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30606941/incremental-prognostic-value-of-platelet-count-in-patients-with-acute-heart-failure-a-retrospective-observational-study
#9
Satoshi Yamaguchi, Masami Abe, Tomohiro Arakaki, Osamu Arasaki, Michio Shimabukuro
BACKGROUND: Acute heart failure (AHF) triggers platelet aggregation and platelet markers are associated with the severity of AHF. The present study aimed to investigate the prognostic value of platelet count (PLT) in patients with AHF. Methods and Results: This single-center retrospective observational study analyzed 425 consecutive patients with AHF. The patients were divided into groups based on tertiles of PLT: low (PLT1 <170,000/μL), intermediate (170,000/μL≤PLT<230,000/μL), and high (PLT3 ≥230,000/μL)...
December 29, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30606940/chest-compression-depth-and-rate-effect-on-instructor-visual-assessment-of-chest-compression-quality
#10
Katsuya Nagafuchi, Toru Hifumi, Naoki Nishimoto, Yutaka Kondo, Kei Yoshikawa, Taku Iwami, Yasuhiro Kuroda
BACKGROUND: The aim of the present study was to determine whether instructors could accurately assess chest compression quality visually, considering the association between chest compression depth and rate. Methods and Results: In this prospective, observational study, the quality of chest compressions performed by a simulated actor in a video was visually assessed by certified instructors. The film consisted of 14 case scenarios, each including a combination of depth (2 patterns: adequate, 5-6 cm; and inadequate, <5 cm) and rate (7 categories: compressions 90-150 times/min in increments of 10 times/min)...
December 29, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30587699/heart-failure-mid-range-ejection-fraction-heart-failure-with-multiple-personalities
#11
Shin-Ichi Momomura, Miyuki Ito
No abstract text is available yet for this article.
December 27, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30587698/safety-of-anticoagulant-therapy-including-direct-oral-anticoagulants-in-patients-with-acute-spontaneous-intracerebral-hemorrhage
#12
Yuki Sakamoto, Chikako Nito, Yasuhiro Nishiyama, Satoshi Suda, Noriko Matsumoto, Junya Aoki, Takashi Shimoyama, Takuya Kanamaru, Kentaro Suzuki, Takuya Nishimura, Masahiro Mishina, Kazumi Kimura
BACKGROUND: Because the efficacy and safety of anticoagulant therapy in patients with acute intracerebral hemorrhage (ICH) are not fully known, present study aimed to elucidate the current status and the safety of anticoagulant therapy, mainly direct oral anticoagulants (DOACs), for acute ICH and anticoagulant-indicated patients. Methods and Results: From September 2014 through March 2017, consecutive patients with acute (<7 days from onset), spontaneous ICH were retrospectively enrolled from a prospective registry...
December 27, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30587697/incidence-rates-of-postoperative-pulmonary-embolisms-in-symptomatic-and-asymptomatic-patients-detected-by-diagnostic-images-a-single-center-retrospective-study
#13
Yoshikazu Matsuoka, Hiroshi Morimatsu
BACKGROUND: Pulmonary embolism (PE) is a serious complication during the perioperative period. However, because most previous studies on the incidence of postoperative PE are based on symptoms, asymptomatic occurrences of PE have been overlooked, and the absolute incidence of postoperative PE remains unknown. The aim of this study was to investigate the incidence of perioperative PE, regardless of its symptoms, by reviewing the clinical interpretations of the diagnostic images obtained during the postoperative period...
December 27, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30587696/survival-of-heart-transplant-candidates-in-japan
#14
Shinichi Nunoda, Taro Sasaoka, Yasushi Sakata, Minoru Ono, Yoshiki Sawa, Mitsuaki Isobe
BACKGROUND: In Japan, there are more patients waiting for heart transplants (HTXs) than available organs. Methods and Results: Since July 2010, 68 pediatric and 366 adult patients aged <60 years applied for HTX candidacy with the Japanese Circulation Society's HTX Committee. No significant differences in freedom from death or HTX were observed between pediatric Status 1 and Status 2 patients. More adult Status 1 patients reached the endpoint of death or HTX than adult Status 2 patients...
December 27, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30587701/underfilled-balloon-expandable-transcatheter-aortic-valve-implantation-with-ad-hoc-post-dilation-pulsatile-flow-simulation-using-a-patient-specific-three-dimensional-printing-model
#15
Masahiro Yamawaki, Kazuto Obama, Saeko Sasuga, Azuma Takahashi, Yoshiaki Ito, Mitsuo Umezu, Kiyotaka Iwasaki
BACKGROUND: Underfilled transcatheter aortic-valve implantation with ad hoc post-dilation is a therapeutic option for patients with borderline annuli to avoid acute complication. The effects of this technique on valve leaflet behavior, hydrodynamic performances, and paravalvular leakage (PVL) using patient-specific three-dimensional (3D) aortic-valve models were investigated. Methods and Results: A female octogenarian patient was treated with this technique by using a 23-mm Sapien-XT...
December 26, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30587700/value-of-placental-growth-factor-as-a-predictor-of-adverse-events-during-the-acute-phase-of-acute-decompensated-heart-failure
#16
Yasuki Nakada, Rika Kawakami, Masaru Matsui, Tomoya Ueda, Tomoya Nakano, Hitoshi Nakagawa, Taku Nishida, Kenji Onoue, Tsunenari Soeda, Satoshi Okayama, Makoto Watanabe, Hiroyuki Okura, Yoshihiko Saito
BACKGROUND: Few biomarkers, even B-type natriuretic peptide (BNP), can predict the long-term outcome in patients with acute decompensated heart failure (ADHF) on the first day of admission. Placental growth factor (PlGF), a member of the vascular endothelial growth factor family of cytokines, is a key molecule in cardiorenal syndrome and a predictor of adverse events in chronic kidney disease patients. However, its significance in ADHF patients remains poorly understood. Methods and Results: We studied 408 ADHF patients admitted between April 2011 and December 2016 by measuring their PlGF levels on the first day of admission...
December 26, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30584231/dynamic-qt-changes-in-long-qt-syndrome-type-8
#17
Mizuki Harada, Hiroshi Suzuki, Seiko Ohno, Junichi Ozawa, Akihiko Saitoh, Minoru Horie
No abstract text is available yet for this article.
December 22, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30584230/outcomes-of-early-onset-acute-type-a-aortic-dissection-influence-of-etiologic-factors
#18
Naoyuki Kimura, Kei Aizawa, Koji Kawahito, Ryo Itagaki, Atsushi Yamaguchi, Yoshio Misawa, Matthias Siepe, Martin Czerny, Friedhelm Beyersdorf, Fabian Alexander Kari, Bartosz Rylski
BACKGROUND: Outcomes of early-onset acute type A aortic dissection (ATAAD) associated with Marfan syndrome (MFS) are known, but not with other etiologies. Methods and Results: ATAAD patients from 2 centers (n=1,001) were divided into 2 groups: age ≤45 years (n=93) and age >45 years (n=908). Although in-hospital death and 10-year survival were similar (12% vs. 7% and 62.6% vs. 67.3%), the 10-year aortic event-free survival differed (50.0% vs. 80.2%; P<0.01). ATAAD patients from 3 centers (n=132), all aged ≤45 years, were divided into 5 groups: lone hypertension (HTN, n=71), MFS (n=23), non-syndromic familial thoracic aortic aneurysm and dissection (NS-FTAAD, n=16), bicuspid aortic valve (BAV, n=11), and no known etiologic factor (n=11)...
December 22, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30584229/corticotropin-releasing-hormone-family-and-their-receptors-in-the-cardiovascular-system
#19
Mikito Takefuji, Toyoaki Murohara
The identification of corticotropin-releasing hormone (CRH) has led to the discovery of a growing family of ligands and receptors. CRH receptor 1 (CRHR1) and CRHR2 are mammalian G-protein coupled receptors (GPCRs) with high affinity for CRH and the CRH family of peptides. CRHR1 is predominantly expressed in the brain and plays a vital role in the hypothalamic-pituitary-adrenal (HPA) axis stress responses by secreting adrenal corticotropic hormone (ACTH). CRHR2 is predominantly expressed in the heart, and a CRHR2-specific ligand, urocortin 2 (UCN2), shows positive cardiac chronotropic and inotropic effects through 3´,5´-cyclic adenosine monophosphate (cAMP) signaling in response to CRHR2-mediated Gαs activation in mice and humans...
December 22, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30568054/pulmonary-sequestration-with-abdominal-aorta-feeding-vessel-in-an-infant
#20
Haisong Bu, Tianli Zhao
No abstract text is available yet for this article.
December 20, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
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