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Journal of Maternal-fetal & Neonatal Medicine

Jelena Boekhoff, Birgit Arabin, Jens Figiel, Siegmund Köhler
AIM: Based on the recent FIGO recommendations, we wish to report on preservation of the uterus in a patient with placenta increta by applying the leaving the placenta in situ approach. METHODS: A 30-year-old gravida 2, Para 1 was referred at 25 + 5 gestational weeks due to a placenta previa bipartita increta diagnosed by transvaginal ultrasound, a history of a cesarean and vaginal bleeding. After informed consent, the parents opted for conservative treatment...
July 16, 2018: Journal of Maternal-fetal & Neonatal Medicine
Hideki Minowa, Kumiko Takagi, Ikuyo Arai, Hajime Yasuhara, Reiko Ebisu, Ayako Ohgitani
OBJECTIVE: The goal of this study was to investigate the prognosis of infants with neonatal respiratory inhibition syndrome (NRIS). METHODS: Infants with a gestational age of at least 36 weeks and a birth weight of at least 2000 grams who were born at Nara Prefecture General Medical Center, in Nara, Japan, between March 2013 and June 2016 were screened for NRIS using our established method. NRIS was defined as severe hypoxemia caused by respiratory inhibition immediately after crying (RIAC) or gastroesophageal reflux (RIGER) or as a respiratory pause during feeding (feeding hypoxemia), accompanied clinically by central cyanosis and a decrease in SpO2 to less than 70%...
July 16, 2018: Journal of Maternal-fetal & Neonatal Medicine
Gökhan Tosun, Abdurrahman Hamdi İnan, Ahkam Göksel Kanmaz, Alper Biler, Alper İleri, Emrah Beyan, Ibrahim Egemen Ertas
OBJECTIVE: The aim of this study was to determine the potential effect of fetal sex on placental delivery times. STUDY DESIGN: This was a prospective observational study of term, singleton, and primiparous pregnant women who underwent vaginal delivery and subsequently delivered a phenotypically normal live infant. Women with labor or pregnancy complications and comorbid diseases were excluded. Women with factors who could lengthen the placental delivery time were also excluded...
July 16, 2018: Journal of Maternal-fetal & Neonatal Medicine
Claire O'Reilly, Mark P Hehir, Rhona Mahony
OBJECTIVE: Rates of vaginal breech delivery at term have fallen significantly. We sought to examine rates of preterm vaginal breech delivery and outcomes associated with delivery route. METHODS: This retrospective cohort study was carried out at a large tertiary referral center serving an urban population, from 2001-2011. The primary objective was to compare outcomes of breech presenting preterm infants according to mode of delivery. The incidence of preterm breech delivery was examined as well as maternal and neonatal outcomes associated with vaginal and abdominal delivery of preterm breech infants...
July 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
Jian-Wei Wang, Shuang-Shuang Cao, Ru-Ying Hu, Meng Wang
AIMS: Several studies have been carried out to examine the association between cigarette smoking during pregnancy and risk of developing gestational diabetes mellitus (GDM), yet the findings are mixed. Therefore, we aimed to estimate the relationship between cigarette smoking during pregnancy and GDM risk. MATERIAL AND METHODS: PubMed, ScienceDirect and Cochrane Library databases were searched up to December 2017. Studies on cigarette smoking during pregnancy and GDM were retrieved...
July 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
Omer Weitzner, Yael Yagur, Tal Weissbach, Gili Man El, Tal Biron-Shental
OBJECTIVE: This study examined the effects of early-onset and late-onset preeclampsia (PE) on short term maternal and neonatal morbidity, as well as risk factors associated with early-onset and late-onset disease. METHOD: This retrospective, cohort study included pregnant women who had been diagnosed with preeclampsia during pregnancy. Electronic medical records were reviewed for demographics and medical history, laboratory tests, and delivery data. The women were grouped according to early-onset preeclampsia (EOPE) - early onset preeclampsia (< 34 weeks) and LOPE - late onset preeclampsia (≥ 34 weeks)...
July 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
Britt J P Kos, Shalem Leemaqz, Catherine D McCormack, Prabha H Andraweera, Denise L Furness, Claire T Roberts, Gustaaf A Dekker
OBJECTIVE: To determine the association between parental MTHFR 677C>T ( RS1801133 ) and 1298A>C ( RS1801131 ) and fetal loss (FL). DESIGN: Case-control study. SETTING: Department of Obstetrics & Gynecology, Lyell McEwin Hospital (LMH) and the women's and Children's Hospital (WCH) in Adelaide, Australia. PATIENTS: A total of 222 couples with FL and 988 couples with uncomplicated pregnancies. MEASUREMENTS: The main outcomes were FL and hyperhomocysteinemia (HHcy)...
July 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
Hérbene José Figuinha Milani, Enoch Quinderé de Sá Barreto, La Hong Chau, Nguyen Ha To, Antonio Fernandes Moron, Simon Meagher, Fabricio Da Silva Costa, Edward Araujo Júnior
OBJECTIVE: Closed spina bifida (CSB) is an abnormality of the posterior arch formation in which the defect is covered by the skin, without protrusion of nervous tissue. The prenatal diagnosis of CSB is very difficult, rarely diagnosed antenatally. METHODS: We present a multicenter case series of six prenatal diagnosis of CSB using two-dimensional (2D) ultrasonography complemented with three-dimensional (3D) ultrasonography and magnetic resonance imaging (MRI). All cases of prenatal diagnosis of CSB were confirmed in the postnatal period/termination of pregnancy by both clinical and/or imaging diagnosis (ultrasonography and MRI)...
July 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
Valentina Bruno, Federica Martelli, Maria Vittoria Capogna, Aly Youssef, Antonella Bruno, Carlo Ticconi, Emilio Piccione, Adalgisa Pietropolli
OBJECTIVE: To evaluate the effects of chorionic villus sampling (CVS) on placental volume, perfusion and vasculature in the first trimester of pregnancy. METHOD: Uterine artery pulsatility index (PI), Placental volume (PV), Vascularization index (VI), Flow Index (FI) and Vascularization Flow Index (VFI) were serially measured in 38 pregnant women who underwent CVS. Thirty-eight women who did not underwent invasive prenatal diagnosis were recruited as controls. RESULTS: CVS was associated with a mild reduction of PI, a reduction of placental VI, FI and VFI and with an increase in PV detected 1 week after the procedure...
July 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
Lami Yeo, Dor Markush, Roberto Romero
Tetralogy of Fallot with pulmonary atresia, a severe form of tetralogy of Fallot, is characterized by the absence of flow from the right ventricle to the pulmonary arteries. This cardiac abnormality is challenging and complex due to its many different anatomic variants. The main source of variability is the pulmonary artery anatomy, ranging from well-formed, confluent pulmonary artery branches to completely absent native pulmonary arteries replaced by major aorto-pulmonary collateral arteries (MAPCAs) that provide all of the pulmonary blood flow...
July 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
Carlo De Pieri, Alessandro Amaddeo, Brigitte Fauroux
No abstract text is available yet for this article.
July 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
Omer E Yapca, Yunus E Topdagi, A Al Ragip
OBJECTIVE: We compared extraperitoneal cesarean section to transperitoneal cesarean on fetal delivery time. MATERIAL AND METHODS: This randomized study included 210 pregnant women undergoing cesarean section for elective reasons, repeat cesarean (< four), or dystocia. Patients who required an urgent cesarean section, who were at high risk for obstetric or maternal bleeding, who had a uterine or adnexal mass, or who requested tubal ligation were excluded from the study...
July 11, 2018: Journal of Maternal-fetal & Neonatal Medicine
Fionnuala Mone, Andrew Thompson, Moira C Stewart, Ricardo Segurado, Jennifer Curry, James C Dornan, Fionnuala M McAuliffe, Michael D Shields
OBJECTIVE: To determine if an elevated fetal umbilical artery Doppler pulsatility index is associated with abnormal respiratory function and atopy in children aged 12 years. METHODS: This prospective case-control study compared children that had an elevated fetal umbilical artery Doppler pulsatility index (> 90th centile) to those with a normal pulsatility index (< 90th centile). All subjects were delivered at full-term and with appropriate growth for gestational age...
July 11, 2018: Journal of Maternal-fetal & Neonatal Medicine
Sebastian Manzanares, Susana Ruiz-Duran, Andrea Pinto, Alicia Pineda, Alberto Puertas
BACKGROUND: Cesarean delivery (CD) is the most frequently performed surgical procedure worldwide. Trial of labor after cesarean (TOLAC) is associated with an increase in perinatal complications related to uterine rupture. However, in general, vaginal birth after cesarean (VBAC) is considered safe and women have less morbidity than those who undergo an elective repeat CD. OBJECTIVE: To develop an integrated model with the best performance criteria for predicting vaginal delivery success after CD...
July 10, 2018: Journal of Maternal-fetal & Neonatal Medicine
Vivian Uchenna Onyia, Maduka Donatus Ughasoro, Obinna Emmanuel Onwujekwe
BACKGROUND: Malaria in pregnancy carries a proven huge health burden; however, the economic challenges have not been properly evaluated in Nigeria. METHODOLOGY: The study was a descriptive cross-sectional hospital-based approach. A structured questionnaire was used to collect microeconomic data from pregnant women, on the medical and nonmedical cost of malaria to them. RESULTS: A total of 371 questionnaires were analyzed (93%; 371/400), of 400 respondents interviewed...
July 10, 2018: Journal of Maternal-fetal & Neonatal Medicine
Michal Fishel-Bartal, Hadel Watad, Chen Hoffmann, Reuven Achiron, Eran Barzilay, Eldad Katorza
INTRODUCTION: Despite meticulous investigation of polyhydramnios cases, in many of these cases, congenital anomalies are detected only after birth. The aim of our study was to explore the contribution of fetal brain MRI to the detection of CNS anomalies in cases of polyhydramnios. MATERIALS AND METHODS: This was retrospective cohort study on fetuses referred for the investigation of polyhydramnios at a single tertiary center. All fetuses underwent a detailed sonographic anatomical scan and a fetal brain MRI...
July 10, 2018: Journal of Maternal-fetal & Neonatal Medicine
Minh-Duy Phan, Thong V Nguyen, Huong N T Trinh, Binh T Vo, Truc M Nguyen, Nguyen H Nguyen, Tho T Q Nguyen, Thuy T T Do, Tuyet T D Hoang, Kiet D Truong, Hoa Giang, Hoai-Nghia Nguyen
OBJECTIVE: Noninvasive prenatal testing (NIPT) for fetal aneuploidies has been widely adopted in developed countries. Despite the sharp decrease in the cost of massively parallel sequencing, the technical know-how and skilled personnel are still one of the major limiting factors for applying this technology to NIPT in low-income settings. Here, we present the establishment and validation of our NIPT procedure called triSure for detection of fetal aneuploidies. METHODS: We established the triSure algorithm based on the difference in proportion of fetal and maternal fragments from the target chromosome to all chromosomes...
July 10, 2018: Journal of Maternal-fetal & Neonatal Medicine
Daniela Doni, Giuseppe Paterlini, Anna Locatelli, Sara Arnoldi, Maria Chiara Magri, Davide Bernasconi, Maria Grazia Valsecchi, Paolo Emilio Tagliabue
Premature birth is a leading cause of neonatal morbidity and mortality. Since gestational age at birth is the most important predictive factor of adverse neonatal outcomes, strategies to postpone premature labor are of major importance. Studies on tocolytic drugs show that COX inhibitors such as indomethacin are superior to others in terms of efficiency in delaying birth, but results concerning neonatal outcomes associated with prenatal exposure to these drugs show controversial results. Indomethacin is also used in the postnatal age for pharmacologic treatment of patent ductus arteriosus (PDA), but no data concerning the effects of antenatal exposure on postnatal ductal patency are available...
July 9, 2018: Journal of Maternal-fetal & Neonatal Medicine
Evrim Bostancı, Cetin Kilicci, Enis Ozkaya, Cigdem Yayla Abide, Mustafa Eroglu
OBJECTIVE: To assess whether intermittent usage of oxytocin infusion increases the duration of active phase of labor and reduces maternal and neonatal complications or not. MATERIAL: Methods: A prospective randomized controlled study was conducted of 200 consenting women with singleton pregnancy in the vertex position undergoing labor induction or augmentation at the Zeynep Kamil Maternity and Children's Training and Research Hospital. Participants with cervical dilation of 3 cm were randomized to either continued or intermittent oxytocin infusion when cervical dilation reached 5 cm...
July 9, 2018: Journal of Maternal-fetal & Neonatal Medicine
Adeeb Khalifeh, Rebecca Eckler, Laura Felder, Gabriele Saccone, Claudia Caissutti, Vincenzo Berghella
OBJECTIVE: To evaluate the incidence of gestational diabetes mellitus (GDM) using the one-step as compared with the two-step approach. STUDY DESIGN: This was a parallel group nonblinded randomized trial conducted at Thomas Jefferson University Hospital (TJUH) in Philadelphia, Pennsylvania from June 2016 to December 2016. The primary outcome was GDM incidence in the one-step compared to the two-approach. Pregnant women without a history of pregestational diabetes were offered screening for GDM at gestational age 24-28 weeks...
July 9, 2018: Journal of Maternal-fetal & Neonatal Medicine
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