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Journal of Maternal-fetal & Neonatal Medicine

Seung Mi Lee, Byoung Jae Kim, Joong Shin Park, Errol R Norwitz, Jeong Won Oh, Sohee Oh, Chanthalakeo Vixay, Sun Min Kim, Chan-Wook Park, Jong Kwan Jun
OBJECTIVE: Prior studies have suggested that nonpresenting twins are more likely to develop respiratory distress syndrome (RDS) than presenting twins. While the underlying mechanism is not known, exposure to intra-amniotic infection/inflammation (IAI) has been associated with a reduced risk of RDS in singleton gestations. In the current study, we compared the risk of RDS in preterm twin neonates according to birth order with adjustment for the presence or absence of IAI. METHODS: The study population consisted of consecutive twin neonates who delivered ≤ 35 weeks and underwent amniocentesis within 7 days of delivery...
September 20, 2018: Journal of Maternal-fetal & Neonatal Medicine
Li Gao, Liyuan Lin, Nan Shan, Chun-Yan Ren, Xin Long, Yu-Han Sun, Wang
BACKGROUND: Omega-3 fatty acid supplementation shows some treatment efficacy for gestational diabetes. This systematic review and meta-analysis is conducted to investigate the efficacy of omega-3 fatty acid supplementation for glycemic control in patients with gestational diabetes. METHODS: The databases including PubMed, Embase, Web of science, EBSCO, and Cochrane Library databases are systematically searched for collecting the randomized controlled trials (RCTs) regarding the efficacy of omega-3 fatty acid versus placebo for gestational diabetes...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Ahmed Altraigey, Mohamed Ellaithy, Hytham Atia, Wegdan Abdelrehim, Ahmed M Abbas, Mufareh Asiri
OBJECTIVE: To endorse the impact of chewing gum on the intestinal functions' restoration, hospital stay and gastrointestinal complications after planned cesarean delivery (CD). METHODS: Women aged between 20 and 35 years scheduled for planned CD; either first or repeated, with term, singleton, viable and healthy pregnancy at obstetrics and gynaecology department, Armed Forces Hospital Southern Region, Khamis Mushayt, Saudi Arabia were invited to participate and randomized if eligible into three groups...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Giovanni Sisti, Evelyn Minis, Mariarosaria Di Tommaso, Astrid Parenti, Sara Paccosi, Steven S Witkin
The pH in the umbilical artery at delivery provides information on the fetal environment and is related to postnatal outcomes. The ability to predict fetal acidemia at delivery would improve clinical management and neonatal well- being. We hypothesized that an alteration in maternal immunity would accompany placental changes that precede a decrease in pH in the fetal circulation in twin gestations. Peripheral blood mononuclear cells (PBMCs), obtained from 86 women with twin pregnancies, were lysed and assayed for concentrations of T cell immunoglobulin mucin domain 3 (Tim-3) and galectin-9 (gal-9) by ELISA...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Shunji Suzuki
No abstract text is available yet for this article.
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Juan Manuel Burgos Luna, Diana Marcela Páez Rúa, Ingrid Ruiz Ordoñez, Paula Andrea Fernández, María Fernanda Escobar Vidarte
INTRODUCTION: Sickle cell disease (SCD) is one of the most common monogenic diseases worldwide, affecting approximately 30 million people across the globe. It is one of the most common hemoglobinopathies affecting pregnancy, particularly in the black population. Pregnant women with SCD, in conjunction with the physiological changes of pregnancy, have an increased risk of developing severe maternal and fetal complications. MATERIALS AND METHODS: A descriptive, observational study was conducted retrospectively to determine the maternal and neonatal disease burden of pregnant women with SCD between 2011 and 2016...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Jiang Xu, Shandong Ye
BACKGROUND: Low-glycemic index (GI) diet might be beneficial for gestational diabetes. However, the results remained controversial. We conducted a systematic review and meta-analysis to explore the influence of low-GI diet on gestational diabetes. METHODS: PubMed, EMbase, Web of Science, EBSCO, and Cochrane library databases were systematically searched. Randomized controlled trials (RCTs) assessing the effect of low-GI diet on gestational diabetes were included...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
David Segal, Yael Baumfeld, Lior Yahav, David Yohay, Yael Geva, Fernanda Press, Adi Y Weintraub
INTRODUCTION: Instrumental delivery is a well-known risk factor for obstetric anal sphincter injuries (OASIS). The specific characteristics among patient undergoing vacuum extraction delivery (VE) are less studied. Therefore, we aimed to evaluate risk factors for OASIS among parturient that underwent a VE delivery in a large university affiliated maternity hospital. MATERIAL AND METHODS: The study population contained 9116 women who delivered by VE in tertiary medical center from 1988 to 2015...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Hadel Watad, Hagai Amsalem, Michal Lipschuetz, Rani Haj-Yahya, Myriam Safrai, Yossef Ezra, Doron Kabiri
OBJECTIVE: To determine whether a single episode of vaginal bleeding occurring between 24 and 34 weeks gestation is associated with preterm delivery and other adverse maternal and neonatal outcomes. STUDY DESIGN: We conducted a retrospective cohort study in the Maternal-Fetal unit of two campuses of a large tertiary, medical center with approximately 12 000 deliveries annually. The study group consisted of all women with a singleton pregnancy between 24 + 0/7 and 33 + 6/7 weeks of gestation, admitted to the high-risk antenatal ward due to a single episode of vaginal bleeding of unknown origin between May 2003 and December 2014...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
N Volpe, C Migliavacca, A Dall'Asta, C T Kaihura, T Ghi, T Frusca
We herein present a case of fetal multiple hemivertebrae detected at antenatal sonography. The use of the 3D technology supported by a new contrast enhancement rendering algorithm (Crystal Vue) has allowed the accurate prenatal classification of the defect, confirmed at follow up, that would have been difficult to define by 2D only.
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Yasemin Dogan, Gulseren Yucesoy, Sabiha Ozkan, Izzet Yucesoy
PURPOSE: The aim of this study was to compare volumetric parameters in the abnormal and normal posterior fossa using the Virtual Organ Computer-aided AnaLysis VOCAL™ technique to determine whether fetuses with an abnormal posterior fossa have different volumes. METHODS: A prospective study was conducted on 17 fetuses with an abnormal posterior fossa including, Dandy Walker malformation (n = 6), vermian hypoplasia (n = 3), mega cisterna magna (n = 8) and 99 healthy control fetuses from 20 to 34 weeks' gestation...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Laily Najafi, Mojtaba Malek, Azadeh Abedini, Maryam Kadivar, Ameneh Ebrahim Valojerdi, Ehsan Zahmatkesh, Abbas Ali Keshtkar, Mohammad E Khamseh
OBJECTIVE: To investigate whether evaluations of antenatal umbilical coiling index (aUCI) could predict postnatal umbilical coiling index (UCI) (pUCI) in people with gestational diabetes mellitus (GDM) compared with normal pregnancy independent of maternal demographic and reproductive characteristics. METHOD: In this prospective study, 105 women with normal pregnancy, and 117 women with pregnancy complicated by GDM were recruited. Ultrasound scan of umbilical cord was performed at 18-23 and 37-41 weeks of gestation (WG)...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Hisaaki Kobayashi, Eugenio Luigi Iorio, Akihiro Yoshino
OBJECTIVE: This study was undertaken to assess the influence of mode of delivery on the balance between pro-oxidant/antioxidant systems in fetal circulation. MATERIALS AND METHODS: Both umbilical arterial and venous blood samples were obtained from 37 pregnant women who delivered by spontaneous vaginal delivery (vaginal delivery (VD) group) and from 29 pregnant women who delivered by elective cesarean section (cesarean section (CS) group). Oxidative stress and antioxidant activity were evaluated by reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP) respectively...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Shotaro Kai, Yasuyuki Fujita, Yuka Sato, Saki Kido, Nobuhiro Hidaka, Ichiro Sakamoto, Kiyoko Kato
Pregnancy after mechanical valve replacement involves high risk. Maternal valve thrombosis and hemorrhagic complications are associated with lethal outcomes; therefore, strict anticoagulant therapy is needed. Our patient was 26-year-old primiparous woman. She had undergone aortic valve replacement with a mechanical valve at 4 years of age and had used warfarin 3 mg per day since then. Because of her desire for a baby, she stopped warfarin and conceived spontaneously. She was referred to our hospital. After being informed of her choices, unfractionated heparin (UFH) administration was started...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Michael J Miller, Patricia Butler, Jamie Gilchriest, Anne Taylor, Monica A Lutgendorf
OBJECTIVES: Hypertensive disorders of pregnancy are a leading cause of maternal morbidity and mortality, studies have shown that standardized protocols for treating severe hypertension improves outcomes. Our goal was to examine the effects of a protocol for treating severe hypertension. METHODS: Using quality improvement methodology, we developed an evidence-based nurse-initiated protocol for management of severe hypertension. We used a before and after study design, with the primary outcome of time to administration of antihypertensive medications and time to achieve blood pressure control...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Mehmet Sukru Budak, Muzaffer Temur
PURPOSE: To examine the influence of the "Physician Unit Performance Coefficient" (PUPC) regulation, which has been taken into force by the TR Ministry of Health in January 2013 in our country, on the cesarean rates in our clinic. METHODS: The pregnant women who gave birth at the Diyarbakır Maternity and Pediatrics Hospital within a period of 3 years before the PUPC has been taken into force and the pregnant women who have birth within a period of 3 years after January 2013, when the regulation has been taken into force, have been divided into two groups as Group 1 and Group 2 respectively...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Sakeer Vayalthrikkovil, Rani Bashir, Maria Espinoza, Leigh Irvine, James N Scott, Khorshid Mohammad
BACKGROUND: Perinatal hypoxia is a recognized cause of hypocalcemia in neonates in the first 3 days of life. Therapeutic hypothermia (TH) promotes neuroprotection by decreasing calcium influx into the cells during the reperfusion phase thereby increase serum calcium levels. This study examines the trends of serum calcium levels in neonates with hypoxic ischemic encephalopathy (HIE) and the effect of TH. MATERIAL AND METHODS: A retrospective cohort study of neonates with moderate to severe HIE admitted to level III neonatal intensive care units (NICU's) in Calgary between September 2011 and October 2015...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Jose R Duncan, Erin J MacDonald, Katherine M Dorsett, Mannu Nayyar, Zoran Bursac, Mauro H Schenone
OBJECTIVES: The American College of Obstetricians and Gynecologists' Task Force on Hypertension in Pregnancy recommends assessing left ventricular function with echocardiogram or electrocardiogram (ECG) in women with severe hypertension of long duration. We aim to compare the rates of superimposed preeclampsia (SIP) and other obstetrical outcomes in pregnancies with chronic hypertension (CHTN) and left ventricular hypertrophy (LVH) by ECG criteria with mothers without LVH. STUDY DESIGN: After IRB approval, we performed a retrospective chart review from January 2015 to December 2016...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Cagri Gulumser, Mahir Kinap, Filiz Bilgin Yanik, Sahin Uysal Nihal, Gokhan Moray, Mehmet Haberal
OBJECTIVE: To investigate pregnancy outcomes and to define preventative measures against to risk factors and complications in pregnancy after liver transplantation. Secondary aim is to report postpartum allograft functions in these patients. METHOD: This is a case series study. All pregnant women with liver transplantations performed in our hospital were enrolled. Patients' hospital medical records, electronic records Neonatal Intensive Care Unit (NICU) records were used to collect to data...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Bharathi Balachander, Nivedita Mondal, Vishnu Bhat, Bethou Adhisivam, Mahesh Kumar, Santhosh Satheesh, Mahalakshmi Thulasingam
BACKGROUND: Currently nonselective cyclooxygenase (COX) inhibitors ibuprofen and indomethacin are approved drugs for closure of patent ductus arteriosus but have potential toxicities. There are reports of the effectiveness of paracetamol in ductal closure. However there is paucity of data comparing paracetamol to ibuprofen or indomethacin in relation to the efficacy and safety profile. METHODS: This randomized clinical trial was done in our tertiary care neonatal unit from October 2014-January 2016 after clearance from ethical committee...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
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