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Journal of Maternal-fetal & Neonatal Medicine

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https://www.readbyqxmd.com/read/28166677/what-factors-are-related-to-recurrent-preterm-birth-among-underweight-women
#1
Anna I Girsen, Jonathan A Mayo, Matthew B Wallenstein, Jeffrey B Gould, Suzan L Carmichael, David K Stevenson, Deirdre J Lyell, Gary M Shaw
OBJECTIVE: Our objective was to identify factors associated with recurrent preterm birth among underweight women. METHODS: Maternally-linked hospital and birth certificate records of deliveries in California between 2007-2010 were used. Consecutive singleton pregnancies of women with underweight body mass index (BMI <18.5 kg/m(2)) in the first pregnancy were analyzed. Pregnancies were categorized based on outcome of the first and second birth as: term-term; term-preterm; preterm-term and preterm-preterm...
February 6, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28166660/population-based-study-on-antenatal-corticosteroid-treatment-in-preterm-small-for-gestational-age-and-non-small-for-gestational-age-twin-infants
#2
Shlomit Riskin-Mashiah, Brian Reichman, David Bader, Amir Kugelman, Valentina Boyko, Liat Lerner-Geva, Arieh Riskin
OBJECTIVES: To assess the associations between antenatal corticosteroid use (ACU), mortality and severe morbidities in preterm, twin neonates and compare these between small for gestational-age (SGA) and non-SGA twins. MATERIALS AND METHODS: Population-based study using data collected by the Israel National Very Low Birth Weight infant database from 1995-2012, comprising twin infants of 24-31 weeks' gestation, without major malformations. Univariate and multivariable logistic regression analyses were performed...
February 6, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28162023/comparison-of-two-risk-assessment-algorithms-for-preeclampsia-in-first-trimester-with-consecutive-intake-of-low-dose-aspirin-in-the-high-risk-group-an-observational-study
#3
Ioana-Claudia Lakovschek, Bence Csapo, Vassiliki Kolovetsiou-Kreiner, Karoline Mayer-Pickel, Philipp Reif, Christina Stern, Daniela Ulrich, Uwe Lang, Barbara Obermayer-Pietsch, Mila Cervar-Zivkovic
We analyzed outcome of women screened for preeclampsia with two different multifactorial risk algorithms (Predictor®Software by PerkinElmer; PERK-group:n = 214 and Viewpoint® by GE Healthcare; VIEW-group:n = 209) in first trimester. Women at high risk for developing preeclampsia were advised to take low-dose acetylsalicylic-acid(LDA). Screening positive rates for early onset preeclampsia differed significantly between the two groups (7.9% vs 26.3%;p = 0.000). According clinical use of screening test criteria LDA was prescribed in 63(29...
February 5, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28162020/holder-pasteurization-affects-s100b-concentrations-in-human-milk
#4
Chiara Peila, Alessandra Coscia, Enrico Bertino, Giovanni Li Volti, Fabio Galvano, Gerard Ha Visser, Diego Gazzolo
PURPOSE: Donor milk (DM) represents an important nutrition source for high-risk newborns. Holder pasteurization (HoP) is the most recommended procedure for DM treatment, providing a good compromise between microbiological safety and biological quality. HoP was previously shown to affect DM cytokines, growth factors and hormones levels, whilst no data concerning the possible effects of HoP on neurobiomarkers (NB) are available. Therefore, our study investigated whether the concentration in DM of a well-known NB involved in brain development/damage, namely S100B, changes due to HoP...
February 5, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28152632/cervical-fluid-calreticulin-and-cathepsin-g-in-pregnancies-complicated-by-preterm-prelabor-rupture-of-membranes
#5
Ctirad Andrys, Ivana Musilova, Marcela Drahosova, Ondrej Soucek, Lenka Pliskova, Bo Jacobsson, Nanbert Zhong, Marian Kacerovsky
OBJECTIVE: The study aimed to determine the cervical calreticulin and cathepsin-G concentrations in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) with respect to the presence of microbial invasion of the amniotic cavity (MIAC) and intra-amniotic inflammation (IAI). METHODS: Eighty women with singleton pregnancies complicated by PPROM were included in this study. Cervical and amniotic fluids were obtained at the time of admission, and concentrations of calreticulin and cathepsin-G in cervical fluid were determined using ELISA...
February 2, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28093002/predictive-value-of-some-hematological-parameters-for-non-invasive-and-invasive-mole-pregnancies
#6
Cigdem Abide Yayla, Enis Özkaya, Ilter Yenidede, Ahmet Eser, Evrim Bostancı Ergen, Ahter Tanay Tayyar, Mehmet Baki Şentürk, Ates Karateke
AIM: The aim of this study was to discriminate mole pregnancies and invasive forms among cases with first trimester vaginal bleeding by the utilization of some complete blood count parameters conjunct to sonographic findings and beta human chorionic gonadotropin concentration. MATERIALS AND METHODS: Consecutive 257 cases with histopathologically confirmed mole pregnancies and 199 women without mole pregnancy presented with first trimester vaginal bleeding who admitted to Zeynep Kamil Women and Children's Health Training Hospital between January 2012 and January 2016 were included in this cross-sectional study...
February 2, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28147892/when-should-repeat-cesarean-delivery-bescheduled-after-two-or-more-previous-cesarean-deliveries
#7
Einav Kadour-Peero, Inna Bleicher, Dana Vitner, Ronen Sloma, Rabea Bahous, Eyal Levy, Shlomi Sagi, Ron Gonen
BACKGROUND: The optimal gestational age for a planned high order cesarean delivery reflects the balance between the risk of neonatal morbidity and the risk of unscheduled cesarean delivery prior to the scheduled date. METHODS: A retrospective cohort study of 656 women with ≥2 previous CDs were divided in two groups of women based on the gestational age at which the CD was scheduled: "38 group" and "39 group". Medical records were reviewed for demographic, medical and obstetrical history, and for adverse maternal and neonatal outcomes...
February 1, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28142291/treatment-of-preeclampsia-with-hydroxychloroquine-a-review
#8
Rahana Abd Rahman, Philip DeKoninck, Padma Murthi, Euan M Wallace
In this review we discuss the potential use of antimalarial drugs as an adjuvant therapy for preeclampsia, focusing on the mechanisms of action of this class of drugs in the context of preeclampsia. In particular, hydroxychloroquine has been shown to have various beneficial effects on patients with systemic lupus erythematosus. There are several pathways targeted by the antimalarial drugs that are similar to the pathophysiology of preeclampsia and hence offering oppurtunities to develop novel therapies to treat the disease...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28140723/placenta-previa-and-maternal-hemorrhagic-morbidity
#9
Karen J Gibbins, Brett D Einerson, Michael W Varner, Robert M Silver
OBJECTIVE: Placenta previa is associated with maternal hemorrhage, but most literature focuses on morbidity in the setting of placenta accreta. We aim to characterize maternal morbidity associated with previa and to define risk factors for hemorrhage. METHODS: This is a secondary cohort analysis of the NICHD Maternal-Fetal Medicine Units Network Cesarean Section Registry. This analysis included all women undergoing primary Cesarean delivery without placenta accreta...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28140722/fetal-echocardiographic-findings-in-right-pulmonary-artery-to-left-atrium-communication-a-case-report-and-review-of-the-literature
#10
Tetsuya Ide, Takekazu Miyoshi, Taka-Aki Matsuyama, Ken-Ichi Kurosaki, Jun Yoshimatsu
Right pulmonary artery to left atrium communication (RPALA com) is a fatal congenital heart disease with right-to-left shunting. We present a rare case of RPALA com that was prenatally diagnosed and confirmed by autopsy. We focus on some unique echocardiographic findings for prenatal diagnosis of RPALA com by reviewing our case and the literature. Asymmetric cardiomegaly with a pear sign and dilatation of the pulmonary artery might be useful for screening tests. A larger stalk with the pear sign, high-velocity of shunt flow, and absence of a dilated pulmonary vein might support the prenatal diagnosis of RPALA com...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28140706/risk-factors-for-brain-damage-among-preterm-twins
#11
Irit Schushan-Eisen, Ayala Maayan-Metzger, Ram Mazkereth, Leah Leibovitch, Tzipora Strauss
AIM: To evaluate the perinatal and postnatal risk factors for various brain pathologies among preterm twins. METHODS: Retrospective data of 104 twin pairs of which one of the siblings had evidence of abnormal head ultrasound (HUS) and its' co-twin with normal HUS served as control. RESULTS: Abnormal HUS consisted of periventricular echodensities among 69 infants, intraventricular hemorrhage among 28 infants, cystic periventricular leukomalacia among 10 infants and other parenchymal brain pathologies among 5 infants...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28140705/the-clinical-research-into-the-application-of-multifunctional-airbag-abdominal-pressure-belt-in-midwifery-and-in-the-prevention-of-postpartum-hemorrhage
#12
Shaofei Zhao, Jiying Wen, Jianmin Niu, Jiaohong Xia, Liping Zhou, Wenxia Zou
OBJECTIVE: Explore the effect of the multifunctional airbag abdominal pressure belt on midwifery and on the prevention of postpartum hemorrhage. METHODS: Select 363 natural delivery cases of hospitalized primiparae and divide them randomly into two groups. In the observation group, 182 primiparae used the multifunctional airbag abdominal pressure belt during the second and third stages of labor, whereas the control group of 181 did not use the belt. Delivery outcomes of the primiparae and their fetus were then observed...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28139962/intra-amniotic-administration-of-lipopolysaccharide-induces-spontaneous-preterm-labor-and-birth
#13
Nardhy Gomez-Lopez, Roberto Romero, Marcia Arenas-Hernandez, Bogdan Panaitescu, Valeria Garcia-Flores, Tara N Mial, Aashna Sahi, Sonia S Hassan
OBJECTIVE: Intra-amniotic infection is associated with spontaneous preterm labor. In most cases, the infection is subclinical and bacteria are detected in the amniotic cavity rather than in the chorioamniotic membranes. The aims of this study were to determine whether the intra-amniotic injection of a microbial product, lipopolysaccharide (LPS), could induce preterm labor/birth, and to compare this model to two established models of LPS-induced preterm labor/birth. METHODS: Pregnant B6 mice received an intra-amniotic, intra-uterine, or intra-peritoneal injection of LPS (100 ng/amniotic sac, 15μg/25μL, and 15μg/200μL respectively) or PBS (control)...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28139952/the-correlation-between-frequency-and-duration-of-breastfeeding-and-the-severity-of-neonatal-hyperbilirubinemia
#14
Hassan Boskabadi, Maryam Zakerihamidi
Introduction inadequate intake of calorie or inadequate breastfeeding can cause neonatal hyperbilirubinemia. The present study was conducted to examine the correlation between frequency and duration of breastfeeding and the severity of neonatal hyperbilirubinemia amongnewborns admitted toGhaem Hospital of Mashhad (Iran) due to neonatal hyperbilirubinemia. Methodology the present cross-sectional study was conducted on 634 newborns with idiopathic hyperbilirubinemia referred to either Emergency Department or Neonatal Clinic in Ghaem Hospital...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28139951/cervical-length-measured-before-delivery-and-the-success-rate-of-vaginal-birth-after-cesarean-vbac
#15
Ron Beloosesky, Nizar Khatib, Nadir Ganem, Emad Matanis, Yuval Ginsberg, Mike Divon, Zeev Weiner
OBJECTIVE: To test the hypothesis that measuring CL close to the time of delivery is a predictor of successful vaginal birth following a cesarean. METHODS: A prospective longitudinal study included women with singleton pregnancies at 38-41 weeks, who previously underwent a cesarean, and who were interested in trial of labor. Patients who did not have a spontaneous onset of labor were induced at 41 weeks gestation. CL measurements were performed prior to labor by transvaginal ultrasound, recorded, and blinded from the caring physicians...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28139950/can-early-%C3%AE-human-chorionic-gonadotropin-predict-birth-of-singletons-and-twins-after-in-vitro-fertilization
#16
Ana Póvoa, Milton Severo, Pedro Xavier, Alexandra Matias, Isaac Blickstein
OBJECTIVE: To assess the predictive value for clinical pregnancy outcome of β-hCG level at 13 days after embryo transfer. METHODS: Retrospective study of IVF clinical pregnancies diagnosed at 6 weeks. We calculated the value of β-hCG level at 13 days after embryo transfer to predict live births. RESULTS: We analyzed 177 IVF cycles between 2009 and 2014 (50 singleton births, 50 twin births, 27 sets with a vanishing twin, 43 first trimester singleton pregnancy loss and 7 first trimester total twin pregnancy loss)...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28139949/computational-model-for-timing-of-delivery-in-an-obese-population
#17
Lisa Gill, Michael Holbert
OBJECTIVE: To estimate the impact on stillbirth risk, cesarean deliveries, and delivery-related healthcare cost associated with induction of labor compared to expectant management of term pregnancies in an obese population. METHODS: A decision analysis model was designed to compare the delivery and cost outcomes associated with a hypothetical cohort of 100,000 term pregnancies, complicated by obesity, that were planning a vaginal delivery. The model predicted stillbirths, cesarean deliveries, and total delivery-related healthcare cost from routine induction at 39 weeks compared to expectant management and routine induction each week from 40 to 42 weeks...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28139946/multiple-sclerosis-in-pregnancy-prevalence-sociodemographic-features-and-obstetrical-outcomes
#18
Alex Fong, Cindy T Chau, Cara Quant, Jennifer Duffy, Deyu Pan, Dotun A Ogunyemi
OBJECTIVE: We sought to describe the prevalence, sociodemographic features, and antenatal/peripartum outcomes of multiple sclerosis (MS) in pregnancy. STUDY DESIGN: A retrospective cohort study was performed using deliveries in California from 2001-2009. Cases of MS as well as other morbidities were identified via ICD-9-CM code. Logistic regression was performed to adjust for potential confounders. RESULTS: 1,185 out of 4,424,049 deliveries were complicated by MS...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28139937/risk-factors-for-tracheostomy-requirement-in-extremely-low-birth-weight-infants
#19
Orly L Levit, Veronika Shabanova, Alia Bazzy-Asaad, Matthew J Bizzarro, Vineet Bhandari
AIM: To identify variables that affect the risk for tracheostomy in a population of extremely low birth weight (ELBW) infants. METHODS: A retrospective matched case-control study was conducted. ELBW infants with a tracheostomy were compared with controls without tracheostomy. Data collection included demographics, detailed information about each intubation and extubation attempt, the use of steroids and the presence of comorbidities. Statistical analyses include conditional logistic regression and Poisson regression for clustered observations...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28081638/echocardiography-may-cause-significant-pain-response-in-preterm-infants
#20
Selma Aktas, Dilek Ulubas, Mehmet Gumustas, Ibrahim Murat Hirfanoglu, Canan Turkyilmaz, Ebru Ergenekon, Esin Koc, Yildiz Atalay, Nihal Demirel, Ahmet Yagmur Bas, Eray Esra Onal
OBJECTIVE: The objective of this study is to evaluate if echocardiographic examination causes any pain response in term and preterm infants. METHODS: Term and preterm neonates who admitted to Neonatal Intensive Care Unit at Gazi University Hospital and Etlik Zubeyde Hanim Training and Research Hospital and were performed echocardiography for any reason were included into the study. Neonates were evaluated before, during and 10 minutes after the examination. Vital signs (heart rate, respiratory rate, blood pressure, transcutaneous oxygen saturation) were recorded...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
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