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Epilepsy Currents

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https://www.readbyqxmd.com/read/30254528/practice-guideline-update-summary-efficacy-and-tolerability-of-the-new-antiepileptic-drugs-ii-treatment-resistant-epilepsy-report-of-the-american-epilepsy-society-and-the-guideline-development-dissemination-and-implementation-subcommittee-of-the-american-academy
#1
Andres M Kanner, Eric Ashman, David Gloss, Cynthia Harden, Blaise Bourgeois, Jocelyn F Bautista, Bassel Abou-Khalil, Evren Burakgazi-Dalkilic, Esmeralda Llanas Park, John Stern, Deborah Hirtz, Mark Nespeca, Barry Gidal, Edward Faught, Jacqueline French
Objective: To update the 2004 American Academy of Neurology (AAN) guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). Methods: 2004 criteria were used to systematically review literature (January 2003 to November 2015), classify pertinent studies according to the therapeutic rating scheme, and link recommendations to evidence strength. Results: Forty-two articles were included. Recommendations: The following are established as effective to reduce seizure frequency (Level A): immediate-release pregabalin and perampanel for TR adult focal epilepsy (TRAFE); vigabatrin for TRAFE (not first-line treatment; rufinamide for Lennox-Gastuat syndrome (LGS) (add-on therapy)...
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254527/practice-guideline-update-summary-efficacy-and-tolerability-of-the-new-antiepileptic-drugs-i-treatment-of-new-onset-epilepsy-report-of-the-american-epilepsy-society-and-the-guideline-development-dissemination-and-implementation-subcommittee-of-the-american
#2
Andres M Kanner, Eric Ashman, David Gloss, Cynthia Harden, Blaise Bourgeois, Jocelyn F Bautista, Bassel Abou-Khalil, Evren Burakgazi-Dalkilic, Esmeralda Llanas Park, John Stern, Deborah Hirtz, Mark Nespeca, Barry Gidal, Edward Faught, Jacqueline French
Objective: To update the 2004 American Academy of Neurology (AAN) guideline for treating new-onset focal or generalized epilepsy (GE) with second- and third-generation antiepileptic drugs (AEDs). Methods: The 2004 AAN criteria was used to systematically review literature (January 2003 to November 2015), classify pertinent studies according to the therapeutic rating scheme, and link recommendations to evidence strength. Results: Several second-generation AEDs are effective for new-onset focal epilepsy. Data are lacking on efficacy in new-onset generalized tonic-clonic seizures, juvenile myoclonic epilepsy, or juvenile absence epilepsy, and on efficacy of third-generation AEDs in new-onset epilepsy...
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254526/trading-up-to-a-new-model-of-stxbp-encephalopathy
#3
COMMENT
Matthew Weston
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254525/thinking-above-the-genome-epigenetic-manipulation-as-a-disease-modifying-strategy-in-epilepsy
#4
COMMENT
Nigel C Jones
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254524/the-stuff-of-memories-sharp-wave-ripple-memory-consolidation-in-epilepsy
#5
COMMENT
Laura A Ewell
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254523/irritable-no-more-activating-mossy-cells-for-the-treatment-of-epilepsy
#6
COMMENT
Young J Kim, Robert F Hunt
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254522/-shake-it-off-versus-in-your-wildest-dreams-thalamus-as-a-consciousness-gate-for-temporal-lobe-seizures
#7
COMMENT
Libor Velíšek
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254521/neuroinflammation-and-seizures-after-pediatric-brain-injury-what-a-headache
#8
COMMENT
Bret N Smith
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254520/modeling-pediatric-epilepsy-through-ipsc-based-technologies
#9
Dina Simkin, Evangelos Kiskinis
In the current review, we discuss the process of modeling pediatric epileptic encephalopathies with a focus on in vitro iPSC-based technologies. We highlight the potential benefits as well as the challenges of these approaches and propose appropriate standards for the field.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254519/the-key-to-fame-intronic-repeat-expansions-cause-human-epilepsies
#10
COMMENT
Ingrid E Scheffer
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254518/long-term-patterns-of-seizure-recurrence-estimating-risk-from-ambulatory-intracranial-eeg-recordings
#11
COMMENT
Bernard S Chang
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254517/it-helps-2no-when-to-stop-continuous-eeg-monitoring-in-critically-ill-patients
#12
COMMENT
Aatif M Husain
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254516/global-warming-for-psychogenic-nonepileptic-seizures-report-from-ilae-climate-survey
#13
COMMENT
Barbara A Dworetzky
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254515/sudep-when-the-nightmare-becomes-the-reality
#14
COMMENT
Katherine C Nickels
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254514/epileptic-seizures-brain-volume-changes-and-brain-damage-what-do-we-know-so-far
#15
COMMENT
R Edward Hogan
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254513/take-two-deep-breaths-and-call-me-in-the-morning
#16
COMMENT
M Scott Perry
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254512/paying-attention-to-quality-of-life-epilepsy-and-attention-deficit-hyperactivity-disorder
#17
COMMENT
Jay Salpekar
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254511/fast-very-fast-ultrafast-and-even-faster-how-high-frequency-should-we-be-recording-on-intracranial-eeg
#18
COMMENT
Rafeed Alkawadri, Lawrence J Hirsch
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30254510/psychogenic-nonepileptic-seizures-pnes-as-a-network-disorder-evidence-from-neuroimaging-of-functional-psychogenic-neurological-disorders
#19
Jerzy P Szaflarski, W Curt LaFrance
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
https://www.readbyqxmd.com/read/30233275/summary-of-antiepileptic-drugs-available-in-the-united-states-of-america-working-toward-a-world-without-epilepsy
#20
David G Vossler, Mindl Weingarten, Barry E Gidal
No abstract text is available yet for this article.
July 2018: Epilepsy Currents
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