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Yujiro Nakazawa, Fumiyo Tamura, Sae Genkai, Hiroki Shindo, Tomoko Isoda, Miki Mizukami, Takeshi Kikutani
This study aimed to determine the significance of oral ingestion in tube-fed adults. Six males and three females (mean age 48.1 ± 12.4 years) with severe motor and intellectual disabilities were included in this study. The subjects were monitored for cerebral blood flow (CBF) by functional near-infrared spectroscopy imaging, gastric motor function by electrogastrography, and arterial oxygen saturation (SpO2 ) and pulse rate with a biological data monitoring device. The subjects were divided into two groups, settings A and B...
November 14, 2018: Odontology
Ke Ren
Exosomes as a unique subtype of small extracellular vesicles (sEVs) have attracted increasing interest in recent years in the fields of mesenchymal stromal cell (MSC) research. Studies have confirmed that exosomes derived from MSCs preserve immunosuppressive phenotype and can mimic therapeutic benefits of their parent cells. This review briefly summarizes most recent findings on the potential of exosomes as an alternative of therapeutic MSCs, focusing on the role of MSCs and their secreted exosomes in regulation of immune cells, preclinical and clinical evidence of therapeutic outcomes of MSC exosomes, and the biodistribution and pharmacokinetic profile of systemically administered exosomes...
October 15, 2018: Odontology
Kanako Hayashi, Maya Izumi, Yuhei Mastuda, Ayaka Isobe, Sumio Akifusa
The aim of this study is to examin the association between anxiety/depressive tendency and oral health-related quality of life in inpatients of convalescent wards. This cross-sectional study included inpatients of convalescent wards (age range 34-100 years). Data on age, sex, functional independence measure, number of teeth, odontotherapy status, and primary disease for which hospitalization was required were collected. The Hospital Anxiety and Depression Scale (HADS) was used to assess emotional distress...
October 13, 2018: Odontology
Tamami Kadota, Yuko Ogaya, Rina Hatakeyama, Ryota Nomura, Kazuhiko Nakano
The oral cavity is recognized as a major route for infection by Helicobacter pylori, which colonizes the gastric mucosa. Therapeutic options for elimination in patients with digestive disease have been established, though whether antibiotics are effective for H. pylori harbored in the oral cavity as well as oral commensal bacteria remain unknown. A 29-year-old woman visited a gastrointestinal clinic with a chief complaint of stomach ache. Gastroscopy and urine test findings for H. pylori IgG led to a definitive diagnosis of goose bumps gastritis induced by bacteria in the stomach, and triple therapy for H...
October 5, 2018: Odontology
David Donnermeyer, Noushin Vahdat-Pajouh, Edgar Schäfer, Till Dammaschke
The aim was to evaluate the influence of different irrigation solutions on the push-out bond strength (POBS) of three different sealers (AH Plus, BioRoot RCS, GuttaFlow2). Root canals of 180 single-rooted human teeth were instrumented with F360 up to size 45.04. All canals were irrigated with 5 ml NaOCl 3% and 5 ml EDTA 17%. The canals were finally irrigated with either 5 ml NaOCl 3%, CHX 2%, EDTA 17%, citric acid 20% or NaCl 0.9% (n = 36) with a contact time of 5 min and obturated using matching gutta-percha cones according to the single-cone technique in combination with one of the sealers (n = 12)...
October 1, 2018: Odontology
Caroline Mathias, Rafael Soares Gomes, Diogo Dressano, Roberto Ruggiero Braga, Flávio Henrique Baggio Aguiar, Giselle Maria Marchi
Non-invasive treatments for caries lesions are increasingly required for oral health; resin infiltration is one possible conservative option. In this study, we evaluated the effects of diphenyliodonium hexafluorophosphate salt (DPI) on experimental resin infiltrants with either (hydroxyethyl)methacrylate (HEMA) or ethanol as the diluent. A monomeric base with diglycidyl methacrylate ethoxylated (BisEMA, 25 wt%) and triethylene glycol dimethacrylate (TEGDMA, 75 wt%), 0.5 mol% of camphorquinone, and 1 mol% of ethyl-4-(dimethylamino)benzoate (EDAB) was prepared...
October 1, 2018: Odontology
Marco Serafin, Matteo De Biasi, Vittorio Franco, Daniele Angerame
The aim of the present study was to evaluate the difference in cyclic fatigue resistance between OneCurve (OC) and OneShape (OS) endodontic single-file NiTi systems in a severely curved artificial canal. After sample size calculation (α = 0.01; β = 0.20; σ = 20.0; δ = 20.0), 25 OC and 25 OS files were used. An artificial canal with 60° angle and 5-mm radius of curvature was milled in a stainless-steel block reproducing the size and taper of the files used. The test device was electrically heated to maintain the environmental temperature at 37 °C...
September 25, 2018: Odontology
Juan Carlos Flores-Arriaga, Amaury de Jesús Pozos-Guillén, Omar González-Ortega, Diana María Escobar-García, David Masuoka-Ito, Bryan Iván Martín Del Campo-Téllez, Bernardino Isaac Cerda-Cristerna
We explored chitosan-based sustained release pastes for apexification. The study aimed to formulate chitosan-based pastes loaded with calcium hydroxide (CH) or with calcium chloride (CC), and to evaluate the sustained release of Ca2+ and pH changes in deionized water as well as the effect of the pastes on cell viability. The pastes were formulated by dissolution of the chitosan in 1% or 2% acetic acid (AAC) plus the addition of CH or CC, then were suspended in deionized water for 50 days; the released Ca(II) and pH were measured with an electrode probe...
September 18, 2018: Odontology
Takahiro Iwasaki, Hideki Fukuda, Masayasu Kitamura, Yumiko Kawashita, Hideaki Hayashida, Reiko Furugen, Zenya Koyama, Yuichi Ando, Toshiyuki Saito
We investigated the relationship between the number of pairs of posterior teeth and metabolic syndrome (MetS), abdominal obesity (AO), and obesity, among Japanese adults. In 2005, 2,807 Japanese adults aged 25-74 years participated in the Survey of Dental Diseases and the National Health and Nutrition Survey. Based on the survey data, BMI, AO (JAS) determined by the Japan Atherosclerosis Society, AO (IDF) by the International Diabetes Federation, and MetS were assessed. Total functional tooth units (t-FTUs) were scored with pairs of opposing posterior teeth, including artificial teeth...
September 14, 2018: Odontology
Cevat Emre Erik, Taha Özyürek
The aim of the present study was to compare the effect of etidronic acid (HEBP), NaOCl, and EDTA solutions and their combinations on cyclic fatigue resistance of NiTi RPC Blue (RPC Blue), HyFlex EDM (HEDM), and WaveOne Gold (WOG) instruments having different metallurgic characteristics at the body temperature (37 °C). 100 WOG, 100 RPC Blue, and 100 HEDM NiTi files were randomly divided into 5 groups and immersed in the following solutions: group 1, distilled water; group 2, 6% NaOCl; group 3, 17% EDTA; group 4, 18% HEBP; group 5, 6% NaOCl and 18% HEBP...
September 12, 2018: Odontology
Marijana Rincic Mlinaric, Sven Karlovic, Zlatko Ciganj, Darko Pop Acev, Andrej Pavlic, Stjepan Spalj
The effect of oral antiseptics on the corrosion of nickel-titanium (NiTi) alloys with various coating was investigated. Uncoated, titanium nitride-coated and rhodium-coated NiTi archwires (0.020 × 0.020″) were tested in interaction with artificial saliva pH 4.8 and oral antiseptics based on hyaluronic acid (Gengigel), chlorhexidine (Curasept) and essential oils in alcohol base (Listerine). The dynamics of nickel and titanium ions release were recorded during 28 days. Springback ratio and modulus of resilience were assessed by three-point bending test...
September 3, 2018: Odontology
Funda Fundaoğlu Küçükekenci, Ahmet Serkan Küçükekenci, Fatih Çakici
The aim of this in vitro study was to evaluate the preventive efficacy of three dentin tubule occlusion methods against discoloration caused by triple-antibiotic paste (TAP). Sixty extracted human incisors were sectioned, and the access was opened. The specimens were randomly allocated to the following four groups (n = 15): bonding application (BD), teethmate desensitizer (TM), Nd:YAG laser application (LS), and no surface treatment (control, C). Specimens were discolored with TAP over a period of 3 weeks...
August 31, 2018: Odontology
Lucio Lo Russo, Khrystyna Zhurakivska, Graziano Montaruli, Angelo Salamini, Crescenzio Gallo, Giuseppe Troiano, Domenico Ciavarella
Orthodontic treatment has important correlations with periodontal changes. Various mechanical and biological factors are involved in determining such changes, but anatomical and morphological variables, generally addressed as periodontal biotype, play a key role. In measurement of such modifications, digital and non-contact reverse engineering technologies may be of tremendous advantage. The aim of this study is to retrospectively evaluate, in a series of digitized dental casts, some of the parameters addressing periodontal biotype and correlate them to extent and direction of tooth movement...
October 2018: Odontology
Hiroki Katagiri, Kayoko Fukui, Kenjirou Nakamura, Akira Tanaka
The causes of fungemia include immunosuppression and neutropenia stemming from diverse factors as well as the placement of central venous catheters. However, the relationship between fungemia and the oral cavity has not been substantiated. In this study, we explored the pathological conditions of Candida albicans-derived oral candidiasis in a mouse model, which always develops oral mucositis as a complication. In oral candidiasis, the hyphae of C. albicans are believed to primarily invade the stratum granulosum, but not the subepithelium, of the mucous membrane...
October 2018: Odontology
P J Voss, D Steybe, P Poxleitner, R Schmelzeisen, C Munzenmayer, H Fuellgraf, A Stricker, W Semper-Hogg
Antiresorptive-related osteonecrosis of the jaw (ARONJ) is a rare but severe side effect of antiresorptive treatment with bisphosphonates or RANKL-antibody denosumab in patients with malignant diseases or osteoporosis. Whilst osteonecrosis of the jaw (ONJ) related to the administration of bisphosphonates (BPs) has been investigated for more than 1 decade now, only few data are available on denosumab-related ONJ, especially in patients with osteoporosis. From 2008 to 2016, 52 osteoporosis patients were treated with ARONJ in the Department of Oral and Maxillofacial Surgery, University Medical Center Freiburg, Germany...
October 2018: Odontology
Antonio José Ortiz-Ruiz, Iban Jesús Muñoz-Gómez, Ana Pérez-Pardo, Concepción Germán-Cecilia, Yolanda Martínez-Beneyto, Ascensión Vicente
The aim was to evaluate the effect of fluoride varnish on the shear bond strength (SBS) on polished and non-polished intact and demineralized enamel. Bovine incisors (half demineralized) were used. Bifluorid 12™ was applied. Bonding was made with Futurabond® M + and GrandioSO, 24 h and 7 days after varnishing. In some groups, varnish was removed by polishing before bonding. SBS was measured. Fracture type was determined by stereomicroscopy and scanning electron microscope (SEM) observations of the enamel surface were made...
October 2018: Odontology
Hakan Kamalak, Aliye Kamalak, Ali Taghizadehghalehjoughi, Ahmet Hacımüftüoğlu, Kemal Alp Nalcı
The aim of this study was to investigate potential cellular responses and biological effects of new generation dental composites on cortical neuron cells in two different exposure times. The study group included five different bulk-fill flow able composites; Surefil SDR Flow, X-tra Base Flow, Venus Bulk Flow, Filtek Bulk Flow and Tetric-Evo Flow. They were filled in Teflon molds (Height: 4 mm, Width: 6 mm) and irradiated for 20 s. Cortical neuron cells were inoculated into 24-well plates. After 80% of the wells were coated, the 3 µm membrane was inserted and dental filling materials were added...
October 2018: Odontology
Luigi Generali, Erica Campolongo, Ugo Consolo, Carlo Bertoldi, Luciano Giardino, Francesco Cavani
The aim of this study was to compare the effects of Manual Dynamic Agitation and Passive Ultrasonic Irrigation on sodium hypochlorite (NaOCl) penetration into dentinal tubules using its bleaching ability. Thirty-four single-rooted teeth with round-shaped root canals were distributed in two homogeneous groups and one control group, characterized by different NaOCl activation systems: Manual Dynamic Agitation and Passive Ultrasonic Irrigation. After instrumentation, all root canals were stained with 10% copper sulphate solution followed by 1% rubeanic acid alcohol solution under vacuum...
October 2018: Odontology
Kosaku Sawada, Ken Nakahara, Maiko Haga-Tsujimura, Tateyuki Iizuka, Masako Fujioka-Kobayashi, Kensuke Igarashi, Nikola Saulacic
This study aimed to evaluate the impact of three types of block bone substitute material on bone formation and graft resorption in vivo. Standardized bone defects (n = 4 defects/animal) were created in the calvaria of nine dogs. Block bone substitutes made of deproteinized bovine bone mineral (DBBM), beta-tricalcium phosphate (β-TCP) and a mixture alpha-TCP and hydroxyapatite (α-TCP/HA) were inserted into the bone defects. A fourth defect was left untreated (empty). All sites were covered with a collagenous membrane...
October 2018: Odontology
Elzbieta Klimuszko, Karolina Orywal, Teresa Sierpinska, Jarosław Sidun, Maria Golebiewska
Enamel is the structure that covers the entire clinical crown of a tooth. It enables to chew and crush food, and gives a final shape to the crowns of teeth. To evaluate calcium and magnesium contents in tooth enamel and analyse relationships between the study minerals extracted human permanent teeth were cut at every 150 microns and subjected into acid biopsy. The amounts of calcium and magnesium were assessed in the laboratory using atomic absorption spectroscopy with an air/acetylene flame. The lowest calcium and magnesium contents were found on the enamel surface of the teeth...
October 2018: Odontology
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