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Aging Clinical and Experimental Research

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https://www.readbyqxmd.com/read/29779091/two-years-of-maintenance-hemodialysis-has-a-pronounced-effect-on-arterial-stiffness-progression
#1
Agne Laucyte-Cibulskiene, Laurynas Rimsevicius, Liutauras Gumbys, Dileta Valanciene, Marius Miglinas
BACKGROUND: The change of aortic stiffness, but not the particular baseline value, plays a crucial role in estimating the patient risk with end-stage renal disease. Therefore, we aimed to analyze the evolution of central and peripheral arterial stiffness in hemodialysis population without previous cardiovascular events during a 2-year follow-up. METHODS: 60 hemodialysis patients (mean age 57.61 ± 13.01 years) were prospectively interviewed, and they underwent blood tests, chest X-ray for aortic calcification evaluation and pulse wave velocity (PWV) measurements at the baseline, after 6 months and after 2 years of observation period...
May 19, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29777477/cardiac-and-gait-rhythms-in-healthy-younger-and-older-adults-during-treadmill-walking-tasks
#2
Matthew W Wittstein, Joseph M Starobin, Randy J Schmitz, Sandra J Shulz, Francis Jay Haran, Christopher K Rhea
BACKGROUND: Aging and pathology result in changes in the dynamics of several physiological subsystems. Often, these changes are concurrent, altering the dynamics between subsystems. Cardiac and gait rhythms are one example in which patterns change during physical activity. AIMS: The purpose of this research is to simultaneously monitor changes in cardiac and gait rhythms when participants complete various treadmill walking tasks-normal speed, fast speed, and while synchronizing steps with a blinking metronome...
May 17, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29777476/comparison-of-procalcitonin-a-potentially-new-inflammatory-biomarker-of-frailty-to-interleukin-6-and-c-reactive-protein-among-older-chinese-hospitalized-patients
#3
Ying Yang, Qiukui Hao, Joseph H Flaherty, Li Cao, Jianghua Zhou, Li Su, Yanjiao Shen, Birong Dong
AIM: Procalcitonin (PCT) has predictive value for patients with infectious diseases, but has not been studied in frailty. The purpose of this study was to compare PCT to two other inflammatory biomarkers [interleukin-6 (IL-6)] and C-reactive protein (CRP) in their association with frailty among older hospitalized patients. METHODS: Retrospective study of inpatients (June-December, 2016), who had all three biomarkers measured within 24 h of admission. Frailty was defined according to the Chinese version of a validated frailty scale...
May 17, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29777475/effects-of-resistance-training-detraining-and-retraining-on-strength-and-functional-capacity-in-elderly
#4
Raphael Luiz Sakugawa, Bruno Monteiro Moura, Lucas Bet da Rosa Orssatto, Ewertton de Souza Bezerra, Eduardo Lusa Cadore, Fernando Diefenthaeler
BACKGROUND: The interruption of training (detraining) results in loss of the gains acquired. Partial retention could occur after detraining, and variation in training stimuli may optimize retraining adaptations. AIM: To evaluate the effect of a resistance-retraining program on strength and functional capacity performance after a detraining period. METHODS: Ten elderly men and women (63-68 years) completed 12 weeks of training, 16 weeks of detraining, and 8 weeks of retraining...
May 17, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29766448/cross-sectional-study-on-hospitalizations-related-to-herpes-zoster-in-an-italian-region-2008-2016
#5
Silvia Cocchio, Tatjana Baldovin, Patrizia Furlan, Chiara Bertoncello, Alessandra Buja, Mario Saia, Marco Fonzo, Vincenzo Baldo
INTRODUCTION: To assess the burden of herpes zoster (HZ) by analyzing HZ-related hospital admissions. METHODS: We conducted a population-based descriptive cross-sectional study on all hospitalizations for HZ among the resident population admitted to all public and accredited private hospitals in the Veneto Region (north-east Italy) during the years 2008-2016. HZ hospitalizations were identified from the International Classification of Diseases codes in the hospital discharge records...
May 15, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29752608/author-correction-reliability-and-feasibility-of-gait-initiation-centre-of-pressure-excursions-using-a-wii-%C3%A2-balance-board-in-older-adults-at-risk-of-falling
#6
James Lee, Graham Webb, Adam P Shortland, Rebecca Edwards, Charlotte Wilce, Gareth D Jones
In the original publication, the article title was incorrectly published as 'Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of failing'. The correct title should read as 'Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of falling'.
May 12, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29744683/temporal-characteristics-of-imagined-and-actual-walking-in-frail-older-adults
#7
Hideki Nakano, Shin Murata, Kayoko Shiraiwa, Hiroaki Iwase, Takayuki Kodama
BACKGROUND: Mental chronometry, commonly used to evaluate motor imagery ability, measures the imagined time required for movements. Previous studies investigating mental chronometry of walking have investigated healthy older adults. However, mental chronometry in frail older adults has not yet been clarified. AIMS: To investigate temporal characteristics of imagined and actual walking in frail older adults. METHODS: We investigated the time required for imagined and actual walking along three walkways of different widths [width(s): 50, 25, 15 cm × length: 5 m] in 29 frail older adults and 20 young adults...
May 9, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29736892/validation-of-the-spanish-version-of-the-pittsburgh-fatigability-scale-for-older-adults
#8
Laura M Pérez, Marta Roqué, Nancy W Glynn, Adam J Santanasto, Maria Ramoneda, Maria T Molins, Laura Coll-Planas, Patricia Vidal, Marco Inzitari
BACKGROUND: The Pittsburgh Fatigability Scale (PFS) is the only validated scale for measuring perceived fatigability in older adults. AIMS: We validated the PFS Spanish version by assessing convergent validity with respect to several measures of physical performance, physical activity, physical function and disability. METHODS: A cross-sectional validation study of 79 community-dwelling older adults aged 70 and older from Barcelona, Spain was included...
May 8, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29730844/benzodiazepine-ingestion-as-a-way-to-die-by-suicide-and-related-safety-the-case-of-an-elderly-patient
#9
Laura Cremaschi, Benedetta Grancini, Vera De Carlo, Sara Pozzoli, A Carlo Altamura, Bernardo Dell'Osso
Benzodiazepines (BDZs) are widespread psychotropic compounds, often prescribed as first-line symptomatic option by general practitioners in patients with different psychiatric disorders. Sometimes, however, they contribute to delay the administration of the first appropriate psychopharmacological treatment, thus leading to a longer duration of untreated illness in patients with depressive and anxiety disorders. The well-established pros of BDZs use in clinical practice include efficacy, rapidity of action, versatility, and safety...
May 5, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29728985/prognostic-value-of-cardiac-troponin-i-assay-in-hospitalized-elderly-patients
#10
Francesca Attanasio, Pamela Carrer, Anna Zurlo, Anna Rossi, Luciano Babuin, Monica Maria Mion, Martina Zaninotto, Mario Plebani, Sabino Iliceto, Enzo Manzato, Valter Giantin
BACKGROUND: Cardiac troponin I (cTnI) has been poorly studied in elderly inpatients. AIM: This study wanted to assess factors influencing the increase in cTnI and its prognostic value in hospitalized elderly patients. METHODS: 354 elderly (mean age of 84.8 ± 6.9 years) patients consecutively admitted in the Geriatrics Division in Padua were tested for cTnI levels assay during the hospital stay. Number of subsequent patient deaths at 6 months and 2 years were registered...
May 4, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29721783/study-of-diagnostic-accuracy-of-fagan-s-two-step-nomogram-in-increasing-the-value-of-predictive-tools-for-prostate-cancer-application-of-specific-spatial-distribution-of-positive-negative-bioptic-cores-to-predict-extracapsular-extension
#11
Fabrizio Dal Moro, Tommaso Prayer-Galetti, Lorenzo Angelini, Fabio Vianello, Marina Gardiman, Massimo Rugge, Filiberto Zattoni
BACKGROUND: Prostate cancer (PC) represents the second most frequent cancer in the male population worldwide. It is mandatory to have a very accurate staging to choice the best possible treatment. AIMS: To test the possibility of improving the performance of Partin's tables in predicting the pathological staging of PC by introducing bioptic parameters through an innovative statistic tool (Fagan's two-step nomogram). METHODS: We prospectivelly collected data of all 1048 consecutive patients undergoing saturation 24-core transrectal prostate biopsy...
May 2, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29721782/herpes-zoster-in-frail-elderly-patients-prevalence-impact-management-and-preventive-strategies
#12
REVIEW
Ermanno Zorzoli, Francesca Pica, Giulia Masetti, Elisabetta Franco, Antonio Volpi, Giovanni Gabutti
Population aging is a worldwide phenomenon with significant and manifold impacts on society. Advanced age correlates with the onset of frailty. In this vulnerable state, the immune response is weakened and a higher susceptibility to infectious diseases is observed. The present narrative review aims to cover the topic of herpes zoster (HZ) and its complications in frail populations. The lifetime risk of developing HZ is estimated at about 20-30%, and the risk increases with age. In older people, HZ can lead to the inability to recover the lifestyle, the interests, and the level of activity that existed before its development...
May 2, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29714028/the-prevalence-and-health-burden-of-malnutrition-in-belgian-older-people-in-the-community-or-residing-in-nursing-homes-results-of-the-nutriaction-ii-study
#13
Maurits F J Vandewoude, Janneke P van Wijngaarden, Lieven De Maesschalck, Yvette C Luiking, André Van Gossum
INTRODUCTION: In 2008, the NutriAction study showed that (risk of) malnutrition was highly prevalent (57%) among Belgian older people living in the community or in a nursing home. In 2013, this study was repeated to re-evaluate the occurrence of malnutrition, as well as mobility problems and dependence in activities of daily living (ADL). METHODS: Health care professionals (HCPs) associated with homecare organizations and nursing homes across Belgium were invited to screen their patients and complete an online questionnaire...
April 30, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29714027/self-monitoring-to-increase-physical-activity-in-patients-with-cardiovascular-disease-a-systematic-review-and-meta-analysis
#14
REVIEW
Yuji Kanejima, Masahiro Kitamura, Kazuhiro P Izawa
BACKGROUND AND AIMS: It is important to encourage physical activity in patients with cardiovascular disease (CVD), and self-monitoring is considered to contribute to increased physical activity. However, the effects of self-monitoring on CVD patients remain to be established. In this study, we examined the influence of self-monitoring on physical activity of patients with CVD via a systematic review and meta-analysis. METHODS: Screening of randomized controlled trials only was undertaken twice on PubMed (date of appraisal: August 29, 2017)...
April 30, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29714026/when-and-where-in-aging-the-role-of-music-on-source-monitoring
#15
Rocco Palumbo, Nicola Mammarella, Alberto Di Domenico, Beth Fairfield
Difficulties in source monitoring (SM) tasks observed in healthy older adults may be linked to associative memory deficits since SM requires individuals to correctly bind and later remember these bound features to discriminate the origin of a memory. Therefore, focusing attention on discriminating factors that may attenuate older adults' difficulties in attributing contextual information to memories is necessary. We investigated the effect of affective information on source monitoring in younger and older adults by manipulating the type of affective information (pictures and music) and assessing the ability to remember spatial and temporal source details for affective pictures encoded while listening to classical music...
April 30, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29705888/a-physical-exercise-program-using-music-supported-video-based-training-in-older-adults-in-nursing-homes-suffering-from-dementia-a-feasibility-study
#16
Joke Spildooren, Ite Speetjens, Johan Abrahams, Peter Feys, Annick Timmermans
BACKGROUND: Motivation towards an exercise program is higher in a small group setting in comparison to individual therapy. Due to attentional problems, group exercises are difficult for people with Alzheimer disease (AD). This study evaluates the feasibility of a music-supported video-based group exercise program in older adults suffering from AD. METHODS: Five participants with moderate AD were recruited from a nursing home. A progressive physical exercise program using a video-based training with musical accompaniment was performed and digitally recorded to investigate the adherence and performed accuracy of the exercises...
April 28, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29704209/neurologic-manifestations-of-elderly-patients-with-cancer
#17
Bernardo Cacho-Díaz, Nydia A Lorenzana-Mendoza, Gervith Reyes-Soto, José A Ávila-Funes, Ana P Navarrete-Reyes
BACKGROUND: The incidence of cancer is an age-related phenomenon; therefore, the interest on clinical manifestations, diagnostic approach and treatment strategies for older patients diagnosed with cancer has increased lately. Neurologic symptoms are one of the main reasons for consultation and a common cause of decreased quality of life among cancer patients. AIMS: To identify the neurologic manifestations of patients ≥ 65 years of age diagnosed with cancer and compare them to those presented by a younger population...
April 27, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29700758/assessing-sarcopenia-with-vastus-lateralis-muscle-ultrasound-an-operative-protocol
#18
Andrea Ticinesi, Marco V Narici, Fulvio Lauretani, Antonio Nouvenne, Elena Colizzi, Marco Mantovani, Andrea Corsonello, Francesco Landi, Tiziana Meschi, Marcello Maggio
BACKGROUND: Muscle ultrasound (MUS) has so far not been implemented for sarcopenia assessment in clinical geriatric practice due to allegedly low reproducibility of results in the absence of standardization of procedures. However, rigorous and standardized application of this technique yields highly reproducible results. Its application, especially if integrated with clinical evaluation and comprehensive geriatric assessment, proofs very useful for rapidly obtaining information on muscle mass and architecture...
April 26, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29687304/improved-outcomes-following-implementation-of-a-multidisciplinary-care-pathway-for-elderly-hip-fractures
#19
Raina Wallace, L D George Angus, Swapna Munnangi, Sally Shukry, Jody C DiGiacomo, Charles Ruotolo
BACKGROUND: Hip fractures in patients 65 years and older are associated with significant morbidity and mortality. With the steady increase in the elderly population, we implemented an evidence-based clinical practice guideline for the management of hip fractures to optimize patient care and surgical outcomes. AIMS: To evaluate the effects of a multidisciplinary hip fracture care pathway on patient outcomes in the care of elderly patients. METHODS: A retrospective analysis of the differences in outcomes prior to (January-October 2014) and after (November 2014-April 2016) implementation of a hip fracture care pathway at a regional Level I trauma center was performed...
April 23, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29687303/effects-of-psidium-guajava-linn-leaf-extract-in-japanese-subjects-with-knee-pain-a-randomized-double-blind-placebo-controlled-parallel-pilot-study
#20
Shingo Kakuo, Takashi Fushimi, Keiko Kawasaki, Junji Nakamura, Noriyasu Ota
The extract of Psidium guajava Linn. (guava) leaf was recently revealed to suppress the advance of osteoarthritis (OA) in rat anterior cruciate ligament-transection models. To investigate the efficacy of guava leaf extract in improving knee pain, which is a common symptom of OA, we conducted a double-blind parallel pilot clinical study in Japanese subjects with knee pain. The subjects, who had no medical history of knee treatment, were randomly assigned to two groups with similar total Japanese Knee Osteoarthritis Measure (JKOM) scores...
April 23, 2018: Aging Clinical and Experimental Research
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