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Aging Clinical and Experimental Research

S E R Lim, R Dodds, D Bacon, A A Sayer, H C Roberts
BACKGROUND: Few studies have explored the activity levels of hospitalised older people and the intra-daily activity patterns in this group have not been described. AIMS: To describe the quantity and daily pattern of physical activity among hospitalised older people using two accelerometers: the ankle-worn StepWatch Activity Monitor (SAM), and the wrist-worn GENEActiv. METHODS: This cross-sectional observational study was conducted on the acute medical wards for older people in one UK hospital...
March 14, 2018: Aging Clinical and Experimental Research
Katherine Schultz, Leanne Carroll, Kristin Mainey, Elsa Dent
BACKGROUND: Transition care programs (TCPs) are designed to optimise functional recovery and independence in older adults post-hospitalisation. These programs are under high demand, and understanding inefficiencies in patient flow are a key step towards service improvement. AIMS: To identify service improvement opportunities in an Australian community TCP service. METHODS: An in-depth retrospective study of 113 community TCP clients. RESULTS: TCP occupancy was high (94%) and client functional level improved across the program...
March 10, 2018: Aging Clinical and Experimental Research
Nada El Osta, Lana El Osta, Lydia Rabbaa Khabbaz, Robert Saad, Carole Abi-Ghosn, Martine Hennequin, Stephanie Tubert-Jeannin, Jihad Fakhouri
BACKGROUND AND OBJECTIVE: The percentage of Lebanese older people has increased considerably. Given that Lebanese seniors are marginalized in the health policy-making process, we suggest a high social inequality in oral health that has not been studied so far. The purpose of our study was to describe and compare oral health status in a group of Lebanese older people according to their socioeconomic status (SES) MATERIALS AND METHODS: Participants were recruited from three different primary health care clinics in Beirut, Lebanon...
March 8, 2018: Aging Clinical and Experimental Research
Gabriella Bettelli, Stefania Maggi
No abstract text is available yet for this article.
March 6, 2018: Aging Clinical and Experimental Research
Liliana C Baptista, André Pinto Amorim, João Valente-Dos-Santos, Aristides M Machado-Rodrigues, Manuel Teixeira Veríssimo, Raul A Martins
BACKGROUND: The increasing prevalence of functionally-limited hypertensive individuals highlights the need for interventions to reduce the burden of hypertension-aging-disability and to maximize the chances of healthy aging. AIM: This study aims to compare the effects of multicomponent exercise and different pharmacological treatments on functional status and cardiovascular risk outcomes in hypertensive older adults with comorbidities. METHODS: Participants (n = 96) engage in a 3 days/week multicomponent (aerobic + resistance) exercise program and for one of the following three conditions: (1) thiazide-related diuretics (TDs; n = 33, 69...
March 6, 2018: Aging Clinical and Experimental Research
Tongjian You, Elisa F Ogawa, Saurja Thapa, Yurun Cai, Huan Zhang, Satoshi Nagae, Gloria Y Yeh, Peter M Wayne, Ling Shi, Suzanne G Leveille
BACKGROUND: Chronic pain is associated with poorer cognition and mobility, and fall risk in older adults. AIMS: To investigate the feasibility of a randomized controlled trial of mind-body exercise (Tai Chi) versus a light physical exercise in older adults with multisite pain. METHODS: Adults aged ≥ 65 years with multisite pain who reported falling in the past year or current use of an assistive device were recruited from Boston area communities...
March 6, 2018: Aging Clinical and Experimental Research
P L Bernard, H Blain, G Tallon, G Ninot, A Jaussent, M C Picot, C Belloc, O Coste, J Bousquet, S Ramdani
This study analyzes the evolution in kinematic and non-linear stabilometric parameters in elderly sedentary women selected to participate in a brisk walking program. Ninety-four women were randomly selected for a program of 78 sessions over 6 months, with three sessions of 60 min per week. On the force platform, participants were assessed with both eyes opened as well as eyes closed during a period of 51.2 s and the sampling frequency was 40 Hz. The main dependent kinematic variables were the length, stabilogram surface, and the mean position in anteroposterior as well as medio-lateral directions...
March 5, 2018: Aging Clinical and Experimental Research
Masanori Tsukamoto, Hitoshi Yamanaka, Takeshi Yokoyama
INTRODUCTION: It is important to understand the anesthetic requirements of elderly patients. However, little is known about age-related recovery from inhalational anesthetics. In this retrospective study, we compared age-related differences in recovery from three inhalational anesthetics  in elderly subjects. METHODS: Patients were investigated as three age groups which can be defined as age ranges pediatric (< 15 years), adult (15-64 years), and elderly patients ( > 65 years) under general anesthesia using inhalational anesthetics...
March 3, 2018: Aging Clinical and Experimental Research
Taner Ulus, Kamal Isgandarov, Ahmet Serdar Yilmaz, Ibrahim Vasi, Sayyed Hamed Moghanchızadeh, Fezan Mutlu
BACKGROUND: The development of atrial fibrillation (AF) during the course of acute coronary syndrome (ACS) is related to poor prognosis. Possible predictors of new-onset AF (NOAF) have not been adequately investigated in elderly patients with ACS undergoing percutaneous coronary intervention (PCI). We aimed to identify the factors associated with NOAF in such patients. METHODS: A total of 308 elderly patients with ACS undergoing PCI were enrolled in the study. Patients were divided into two groups: without NOAF [254 patients, 64...
March 2, 2018: Aging Clinical and Experimental Research
Francesca Gimigliano, Antimo Moretti, Alessandro de Sire, Dario Calafiore, Giovanni Iolascon
BACKGROUND: It has been suggested that overweight and obese individuals have an increased risk to develop vitamin D deficiency, commonly associated with poor muscle performance. The relationship among fat mass, vitamin D status, and skeletal muscle is still debated. AIMS: To evaluate the effects of the combination of hypovitaminosis D and overweight on muscle mass and strength, and physical performance in post-menopausal women. METHODS: In this cross-sectional study, we recruited post-menopausal women referring to a physiatric outpatient service for the management of osteoporosis over a 36-month period...
February 27, 2018: Aging Clinical and Experimental Research
Arianna Morano, Agnese Ravera, Luca Agosta, Matteo Sappa, Yolanda Falcone, Gianfranco Fonte, Gianluca Isaia, Giovanni Carlo Isaia, Mario Bo
BACKGROUND: Blood pressure variability (BPV) may have prognostic implications for cardiovascular risk and cognitive decline; however, BPV has yet to be studied in old and very old people. AIMS: Aim of the present study was to evaluate the extent of BPV and to identify variables associated with BPV among older subjects. METHODS: A retrospective study of patients aged ≥ 65 years who underwent 24-h ambulatory blood pressure monitoring (ABPM) was carried out...
February 23, 2018: Aging Clinical and Experimental Research
Thomas Windhaber, Maria Lamprini Koula, Evangelia Ntzani, Alexandra Velivasi, Evangelos Rizos, Michail Theofilos Doumas, Evangelos Elias Pappas, Graziano Onder, Davide Liborio Vetrano, Angel Roudriguez Laso, Leocadio Roudriguez Manjas, Maddalena Illario, Regina Elisabeth Roller-Wirnsberger
BACKGROUND: In addition to the normal process of ageing, frailty, defined as a geriatric syndrome, is becoming more prevalent. Around 10% of people over 65 years and 25-50% of those aged over 85 years are frail. Frail elderly are more vulnerable to external stressors and have an increased risk of adverse health outcomes. To tackle these challenges, European Union (EU) member states need to develop a health work force capable of the right skills mix. A goal-centred education and training of professionals is crucial for effective and efficient health care delivery for Europe's greying population...
February 23, 2018: Aging Clinical and Experimental Research
Seok Tae Yun, Byung Kag Kim, Byung Moon Ahn, Kwang Jun Oh
BACKGROUND: As the population ages, the use of primary total knee arthroplasty (TKA) is on the rise in the octogenarian population. AIMS: The objective of this study was to compare patient-reported outcomes after TKA in octogenarians versus sexagenarians. METHODS: This retrospective case-controlled comparative study with a propensity score matching analysis was conducted by 251 patients who underwent TKA for degenerative osteoarthritis of the knee...
February 22, 2018: Aging Clinical and Experimental Research
Jean-Pierre Pelletier, Johanne Martel-Pelletier
No abstract text is available yet for this article.
February 21, 2018: Aging Clinical and Experimental Research
G Attanasio, F Camerota, M Ralli, G Galeoto, G La Torre, M Galli, M De Vincentiis, A Greco, Claudia Celletti
BACKGROUNDS: Imbalance in elderly is a common problem strictly related to fall. AIMS: This study investigates the possibility that a new protocol based on the focal mechanical muscle vibration may improve balance and stability in elderly. METHODS: Pre-post non-randomized clinical trial has been used. Patients referring postural disequilibrium with negative vestibular bed-side examinations have been treated with focal muscle vibration applied to quadriceps muscles and evaluated before and immediately after therapy and after 1 week and after 1 month with postural stabilometric examination and with an inertial measurement units during the time up and go test...
February 21, 2018: Aging Clinical and Experimental Research
Ilaria Liguori, Gennaro Russo, Luisa Aran, Giulia Bulli, Francesco Curcio, David Della-Morte, Gaetano Gargiulo, Gianluca Testa, Andrea Ungar, Francesco Cacciatore, Domenico Bonaduce, Pasquale Abete
The traditional model of care is based on "disease-centered" management that requires the organization of the hospital in specialized wards, to which the patient is assigned for the main disease. The growing need to optimize economical and human resources and to promote a global approach to the patient has led to the setting up of the intensity of care model. It is a health system based on a "patient-centered" approach, where the hospital is organized in departments dedicated to patients with homogenous needs of care...
February 21, 2018: Aging Clinical and Experimental Research
Jorge G Ruiz, Zubair Rahaman, Stuti Dang, Ramanakumar Anam, Willy M Valencia, Michael J Mintzer
BACKGROUND: Frailty is a state of vulnerability to stressors which results in higher morbidity, mortality and healthcare utilization. The FRAIL scale is used as a validated screening for frailty. The Care Assessment Need (CAN) score is automatically generated from electronic health record data using a statistical model that includes data elements similar to the deficit accumulation model for frailty and predicts risk for hospitalization and/or mortality. AIM: To determine the correlation of the CAN score with the FRAIL scale...
February 21, 2018: Aging Clinical and Experimental Research
Ana Luisa Hernandez-Perez, Ana Gabriela Gallardo-Hernandez, German Ordoñez-Espinosa, Beatriz Martinez-Carrillo, Manuel Gerardo Bermudez-Ochoa, Cristina Revilla-Monsalve, Jose Antonio Sanchez-Lopez, Guillemo Saturno-Chiu, Ronald Leder
OBJECTIVE: A previous multidisciplinary pilot study based on computer simulations for the geriatric population showed that a dose of 0.5 mg/kg/h of propofol could sedate patients older than 65 for pacemaker implantation. The present study validates that the pacemaker implantation can be done in the elderly using 0.5-1 mg/kg/h of propofol with hemodynamic stability. METHODS: 66 patients from 65 to 88 years old scheduled for pacemaker implantation were randomly assigned one of three doses of propofol...
February 21, 2018: Aging Clinical and Experimental Research
Alfredo Raglio, Stefania Filippi, Lucia Leonardelli, Emanuela Trentini, Daniele Bellandi
No abstract text is available yet for this article.
February 20, 2018: Aging Clinical and Experimental Research
Olle Ljungqvist, Martin Hubner
This is a short overview of the principles of a novel development in surgery called enhanced recovery after surgery (ERAS) programs. This is an evidence-based approach to perioperative care that has shown to reduce complications and recovery time by 30-50%. The main mechanism is reduction of the stress reactions to the operation. These principles have been shown to be particularly well suited for the compromised patient and hence very good for the elderly people who often have co-morbidities and run a higher risk of complications...
February 16, 2018: Aging Clinical and Experimental Research
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