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Aging Clinical and Experimental Research

Jean-Marie Robine
No abstract text is available yet for this article.
September 21, 2018: Aging Clinical and Experimental Research
Stany Perkisas, Anne-Marie De Cock, Maurits Vandewoude, Veronique Verhoeven
BACKGROUND: Sarcopenia is a progressive loss of muscle mass, strength, and function. It is linked to functional decline, and secondary to this, to nursing home admission. AIMS: To look into the prevalence of sarcopenia in a nursing home population and to gain insight into the relation of sarcopenia with mortality in this cohort. METHODS: A longitudinal cohort follow-up started in October 2007 in 52 nursing homes in Belgium. Following data were procured: anthropometrics (weight/length), body composition (muscle mass through bio-impedance absorptiometry, BIA), functional status (Katz), nutritional status (mini-nutritional assessment-short form, MNA), and a number of laboratory parameters...
September 14, 2018: Aging Clinical and Experimental Research
Hoa Nguyen, Farhaan Mirza, M Asif Naeem, Mirza Mansoor Baig
Falls are one of the common health and well-being issues among the older adults. Internet of things (IoT)-based health monitoring systems have been developed over the past two decades for improving healthcare services for older adults to support an independent lifestyle. This research systematically reviews technological applications related to falls detection and falls management. The systematic review was conducted in accordance to the preferred reporting items for systematic reviews and meta-analysis statement (PRISMA)...
September 8, 2018: Aging Clinical and Experimental Research
Jordan J Craig, Adam P Bruetsch, Jessie M Huisinga
BACKGROUND: Falling is a significant concern for many elderly adults but identifying individuals at risk of falling is difficult, and it is not clear how elderly adults adapt to challenging walking. AIMS: The aim of the current study was to determine the effects of walking at non-preferred speeds on the coordination between foot and trunk acceleration variability in healthy elderly adults with and without fall history compared to healthy young adults. METHODS: Subjects walked on a treadmill at 80%-120% of their preferred walking speed while trunk and foot accelerations were recorded with wireless inertial sensors...
September 7, 2018: Aging Clinical and Experimental Research
Radcliffe Lisk, Mahir Uddin, Anita Parbhoo, Keefai Yeong, David Fluck, Pankaj Sharma, Michael E J Lean, Thang S Han
BACKGROUND: Most National Health Service (NHS) hospital bed occupants are older patients because of their frequent admissions and prolonged length of stay (LOS). We evaluated demographic and clinical factors as predictors of LOS in a single NHS Trust and derived an equation to estimate LOS. METHODS: Stepwise logistic and linear regressions were used to predict prolonged LOS (upper-quintile LOS > 17 days) and LOS respectively, from demographic factors and acute and pre-existing conditions...
September 6, 2018: Aging Clinical and Experimental Research
Zhila Maghbooli, Arash Hossein-Nezhad, Ghazal Khoshechin, Gelare Niketeghad, Shahrokh Moradi, Elham Adabi, Seyed Ali Asghar Malekhosseini
BACKGROUND: Osteoarthritis (OA) is considered as one of the most common cause of chronic pain and functional disabilities in the elderly. AIM: To examine serum levels of complement-C1q TNF-related protein 3 (CTRP3) in postmenopausal women with knee OA. METHODS: A population-based cross-sectional study was performed in women who complained of chronic knee pain. All subjects were followed by clinical and weight-bearing bilateral anteroposterior radiographical examinations...
September 6, 2018: Aging Clinical and Experimental Research
Marijke Hopman-Rock, Helmi van Hirtum, Paul de Vreede, Ellen Freiberger
BACKGROUND: Activities of daily living (ADL) are often used as predictors of health and function in older persons. This systematic review is part of a series initiated by the European Network for Action on Ageing and Physical Activity (EUNAAPA). AIM: To assess psychometric properties of ADL instruments for use in older populations. METHODS: Electronic databases (Medline, EMBASE, AMED, Psycinfo, CINAHL) were searched, using MeSH terms and relevant keywords...
September 6, 2018: Aging Clinical and Experimental Research
Jaqueline Mello Porto, Renato Campos Freire Júnior, Larissa Bocarde, Júlia Adorno Fernandes, Nise Ribeiro Marques, Natália Camargo Rodrigues, Daniela Cristina Carvalho de Abreu
BACKGROUND: The previous studies have investigated causes of and risk factors for falls and impairment of functional capability in older adults. However, the biomechanical factors involved in functional performance and postural control, and the contribution of hip muscles, are still unknown. AIMS: The aim of the present study was to verify the association between the muscle function of hip abductors and adductors and static and dynamic balance, in a narrow base of support, in community-dwelling older adults...
September 4, 2018: Aging Clinical and Experimental Research
Sara Sabeti, Zeinah Al-Darsani, Bryce Anthony Mander, Maria M Corrada, Claudia H Kawas
BACKGROUND: Several lines of research support associations between sleep and cognition in older adults. However, there is a paucity of data regarding sleep and cognition in nonagenarians and centenarians. AIMS: The current study examined self-reported sleep quantity and sleep quality in relation to hippocampal volume and cognition in adults aged 90 and older. METHODS: A total of 144 participants of The 90+ Study completed The Medical Outcomes Study sleep questionnaire...
September 3, 2018: Aging Clinical and Experimental Research
Fabrício E Rossi, Fábio S Lira, Bruna S A Silva, Ana Paula C F Freire, Ercy M C Ramos, Luis A Gobbo
BACKGROUND: Sarcopenic elderly present low muscle mass and strength, however, it is not clear if the inflammatory and metabolic profile is more related to low lean mass or high fat mass in sarcopenic and non-sarcopenic overfat elderly. AIM: To verify the difference in inflammatory and metabolic responses in sarcopenic and non-sarcopenic overfat elderly and the relationship between these markers, body composition, and strength in this population. METHODS: Fifty-seven elderly were divided into two groups: sarcopenic (n = 30) and non-sarcopenic (n = 27)...
September 3, 2018: Aging Clinical and Experimental Research
Federica Limongi, Marianna Noale, Angelo Bianchetti, Nicola Ferrara, Alessandro Padovani, Elio Scarpini, Marco Trabucchi, Stefania Maggi
AIMS: The purpose of this study was to examine the tools used in Italy to diagnose mild cognitive impairment (MCI). METHODS: In collaboration with the Luigi Amaducci Research Consortium, the Italian Network of Alzheimer Evaluation Units prepared a questionnaire to describe how MCI is diagnosed in the Italian Centres for cognitive disorders and dementia (CCDD). RESULTS: Most of the ninety-two CCDDs participating in the survey were located in hospitals (54...
September 3, 2018: Aging Clinical and Experimental Research
Carlos H Orces
BACKGROUND: Although previous studies have described a positive correlation between physical activity and 25-hydroxyvitamin D concentrations (25(OH)D), there have been inconsistent results in regard to the frequency or intensity of physical activity needed to achieve adequate 25(OH)D status. AIMS: To examine the relationship between self-reported leisure-time physical activity and 25(OH)D3 and 25(OHD) concentrations among US adults aged 60 years and older. METHODS: The present analysis was based on data from participants in the National Health and Nutrition Examination Survey 2007-2012...
September 3, 2018: Aging Clinical and Experimental Research
Alexandre Reynaud, Yong Tang, Yifeng Zhou, Robert F Hess
Most visual and cognitive functions are affected by aging over the lifespan. In this study, our aim was to investigate the loss in sensitivity to different classes of second-order stimuli-a class of stimuli supposed to be mainly processed in extrastriate cortex-in the aging population. These stimuli will then allow one to identify specific cortical deficit independently of visibility losses in upstream parts of the visual pathway. For this purpose, we measured the sensitivity to first-order stimuli and second-order stimuli: orientation-modulated, motion-modulated or contrast-modulated as a function of spatial frequency in 50 aged participants...
August 28, 2018: Aging Clinical and Experimental Research
Robyn E Massa, Andrea Rosso, Andrea L Metti, Patrick J Sparto, Howard Aizenstein, Luigi Ferrucci, Ayushi Divecha, Caterina Rosano
BACKGROUND: In older adults, impaired postural control contributes to falls, a major source of morbidity. Understanding central mechanisms may help identify individuals at risk for impaired postural control. AIMS: To determine the relationship between gray matter volume (GMV), white matter hyperintensities (WMH), mean diffusivity (MD), and fractional anisotropy (FA) with lateral postural control. METHODS: Neuroimaging and postural control were assessed in 193 community-dwelling older adults (mean age 82, 55...
August 28, 2018: Aging Clinical and Experimental Research
Elena Sinforiani, Sara Bernini, Marta Picascia
One thousand and 679 Alzheimer's Disease patients (early onset EO: 152 and late onset LO: 1527) were evaluated after 12, 36 and 60 months. At baseline EO patients have higher Mini Mental State examination (MMSE) and fewer comorbidities in respect to LO group. The MMSE score did not significantly differ after 12, 36 and 60 months; a more marked worsening in instrumental daily activities was observed after 36 months in the EO compared with the LO group. These data allow to conclude that EO patients may have a slight faster progression in the disease within the first 3 years after the diagnosis, but in a longer follow-up no differences exist in respect to LO group...
August 28, 2018: Aging Clinical and Experimental Research
Antonino Davide Romano, Aurelio Lo Buglio, Francesco Bellanti, Rosanna Villani, Gaetano Serviddio, Gianluigi Vendemiale
AIM: Aging is associated with increased inflammation, particularly in frailty. Indeed, such patient presents increased serum inflammatory markers, such as C-reactive protein and interleukin-6. Interleukin-6 is an important stimulating factor for the production of procalcitonin. The aim of this study is to evaluate the diagnostic reliability of serum PCT in the diagnosis of sepsis in frail elderly patients. METHODS: Using Fried's criteria for frailty, 140 older patients hospitalized for any cause were consecutively enrolled and divided in two groups: no-frail (60 patients) and frail (80 patients)...
August 21, 2018: Aging Clinical and Experimental Research
Rachel C Ambagtsheer, Justin Beilby, Julia Dabravolskaj, Marjan Abbasi, Mandy M Archibald, Elsa Dent
BACKGROUND: The primary care setting is the ideal location for identifying the condition of frailty in older adults. AIMS: The aim of this pragmatic study was twofold: (1) to identify data items to extract the data required for an electronic Frailty Index (eFI) from electronic health records (EHRs); and (2) test the ability of an eFI to accurately and feasibly identify frailty in older adults. METHODS: In a rural South Australian primary care clinic, we derived an eFI from routinely collected EHRs using methodology described by Clegg et al...
August 21, 2018: Aging Clinical and Experimental Research
Tomohiro Oka, Tsuyoshi Asai, Hiroki Kubo, Yoshihiro Fukumoto
BACKGROUND: Knee osteoarthritis (OA) and fear of falling (FoF) are important factors contributing to trunk oscillation during walking. It is of a clinical importance to clarify the association of FoF with trunk oscillation during walking in older adults with knee OA (knee OA adults). AIM: The purpose of this study was to investigate the association of FoF with trunk oscillation during walking in knee OA adults. METHODS: Forty-one patients who met the criteria participated in the study and were classified into two groups based on their answer to a question on FoF...
August 20, 2018: Aging Clinical and Experimental Research
Agata Białecka-Dębek, Barbara Pietruszka
BACKGROUND: Ageing is inevitably associated with a progressive cognitive decline. With the rising percentage of the elderly in society, the number of people with dementia and cognitive impairment increases. Water is a vital ingredient that must be included in the diet. The impact of hydration status on cognitive performance has been studied only a little so far. AIMS: The objective of the study was to investigate the relation between the hydration status and the cognitive function...
August 20, 2018: Aging Clinical and Experimental Research
Tomoyuki Kawada
No abstract text is available yet for this article.
August 20, 2018: Aging Clinical and Experimental Research
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