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International Journal of MS Care

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https://www.readbyqxmd.com/read/30374256/editorial
#1
EDITORIAL
Francois Bethoux
No abstract text is available yet for this article.
September 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30374255/total-hip-and-knee-arthroplasty-in-patients-with-multiple-sclerosis
#2
Josef Maxwell Gutman, Kelvin Kim, Ran Schwarzkopf, Ilya Kister
Background: Hip and knee replacements for osteoarthritis are established procedures for improving joint pain and function, yet their safety in patients with multiple sclerosis (MS) is unknown. Patients with MS face unique surgical challenges due to underlying neurologic dysfunction. Current literature on arthroplasty in MS is limited to case reports focusing on adverse events. Methods: Of 40 identified patients who underwent hip or knee replacement, 30 had sufficient data for inclusion...
September 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30374254/-case-report-combining-dalfampridine-with-multicomponent-exercise-and-gait-training-in-a-person-with-multiple-sclerosis
#3
Prudence Plummer, Corinne J Bohling, L Ellese Nickles, Alexis A Williams, Amy Thomas, Silva Markovic-Plese, Barbara Giesser
Background: Dalfampridine extended release (D-ER) improves gait speed in some people with multiple sclerosis (MS), but many patients who take D-ER demonstrate only small improvements of questionable clinical significance. Physical therapy (PT) may augment the treatment effects of D-ER on the nervous system and improve clinical outcomes. This case report describes the successful use of D-ER combined with multicomponent PT in a patient who did not have a clinically important change in gait speed with D-ER alone...
September 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30374253/test-retest-reliability-validity-and-minimal-detectable-change-of-the-balance-evaluation-systems-test-to-assess-balance-in-persons-with-multiple-sclerosis
#4
Kathryn D Mitchell, Han Chen, Sheri P Silfies
Background: Individuals with multiple sclerosis (MS) have balance deficits that result in falls. Balance tests developed for older adults do not discriminate between fallers and nonfallers with MS. The Balance Evaluation Systems Test (BESTest) identifies body systems contributing to imbalance/fall risk. This study evaluated the test-retest reliability and construct validity of the BESTest to assess balance in individuals with MS, compared the diagnostic accuracy of the BESTest and Berg Balance Scale (BBS), and investigated the minimal detectable change of the BESTest in this population...
September 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30374252/five-year-follow-up-of-a-longitudinal-cohort-study-of-the-effectiveness-of-functional-electrical-stimulation-for-people-with-multiple-sclerosis
#5
Tamsyn Street, Christine Singleton
Background: Few studies have examined the long-term consequences of using peroneal nerve functional electrical stimulation (FES) for people with multiple sclerosis (MS). This study examines orthotic effects on a longitudinal cohort and explores additional benefits of FES on self-reported measures such as joint pain. Methods: One hundred forty-five people with foot drop and MS were included (mean age, 52 [range, 28-74] years). Orthotic effects, unassisted walking speed, and clinically important differences (ie, ≥0...
September 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30374251/upper-limb-intention-tremor-in-multiple-sclerosis-an-evidence-based-review-of-assessment-and-treatment
#6
J Keiko McCreary, James A Rogers, Susan J Forwell
Background: To present the current knowledge on the characteristics, assessment, and treatment of upper limb intention tremor to inform and improve future intervention studies in patients with multiple sclerosis (MS), we conducted a literature review for articles on upper limb intention tremor in patients with MS. Methods: Two reviewers conducted searches in PubMed, Web of Science, and MEDLINE (Ovid). Relevant articles, sorted on inclusion criteria, were examined for descriptions and assessments of upper limb intention tremor, and intervention studies were evaluated based on treatment type...
September 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30374250/effects-of-rehabilitation-on-gait-pattern-at-usual-and-fast-speeds-depend-on-walking-impairment-level-in-multiple-sclerosis
#7
Carmela Leone, Alon Kalron, Tori Smedal, Britt Normann, Inez Wens, Bert O Eijnde, Peter Feys
Background: Physical rehabilitation can improve walking capacity in persons with multiple sclerosis (MS). However, changes in spatiotemporal gait parameters after rehabilitation are not frequently evaluated, and it is unknown to what extent potential effects depend on baseline disability level. The objective was to investigate the effectiveness of rehabilitation programs on gait parameters at usual and fastest speeds in persons with MS categorized according to walking speed. Methods: This nonrandomized multinational study in "real-world" settings evaluated participants before and after conventional rehabilitation...
September 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30150905/editorial
#8
EDITORIAL
Francois Bethoux
No abstract text is available yet for this article.
July 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30150904/factors-associated-with-sexual-dysfunction-in-individuals-with-multiple-sclerosis-implications-for-assessment-and-treatment
#9
Samantha Domingo, Tyler Kinzy, Nicolas Thompson, Shauna Gales, Lael Stone, Amy Sullivan
Background: Sexual dysfunction is a common symptom of multiple sclerosis (MS) that often goes unreported by both the patient and the clinician. Sexual dysfunction can affect a person's mood, relationships, daily functioning, and quality of life. Gaining a better understanding of the prevalence and nature of sexual dysfunction in individuals with MS would not only help identify patients with this problem but also determine contributing factors, which can inform treatment alternatives available to the patient...
July 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30150903/-case-report-effect-of-antigravity-treadmill-training-on-muscle-oxidative-capacity-muscle-endurance-and-walking-function-in-a-person-with-multiple-sclerosis
#10
T Bradley Willingham, Jonathan Melbourn, Marina Moldavskiy, Kevin K McCully, Deborah Backus
Background: Exercise training can improve skeletal muscle metabolism in persons with multiple sclerosis (MS). However, quantification of exercise-mediated improvements in muscle metabolism has been limited, particularly in people with high levels of disability. We evaluated the effect of 9 weeks of antigravity treadmill training on muscle oxidative capacity and muscle endurance and assessed the relationship to walking function in a person with MS. Methods: One person with MS (Expanded Disability Status Scale score, 6...
July 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30150902/-case-report-rapid-eye-movement-sleep-behavior-disorder-as-the-first-manifestation-of-multiple-sclerosis-a-case-report-and-literature-review
#11
Alejandro Enriquez-Marulanda, Valentina Quintana-Peña, Yuri Takeuchi, Jairo Quiñones
Rapid eye movement sleep behavior disorder (RBD) is a parasomnia characterized by brief recurrent episodes of loss of muscle atonia during rapid eye movement sleep, with enacted dreams that cause sleep disruption. Patients with multiple sclerosis (MS) have an increased risk compared with the general population to be affected by a sleep disturbance, including RBD. Patients affected, however, uncommonly can present RBD as the first clinical manifestation of MS without other neurologic deficits. These clinical presentations have usually been attributed to inflammatory lesions in the pedunculopontine nuclei, located in the dorsal pons...
July 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30150901/longitudinal-stability-of-cognition-in-early-phase-relapsing-remitting-multiple-sclerosis-does-cognitive-reserve-play-a-role
#12
Roxana M Barbu, Jason A Berard, Louise M Gresham, Lisa A S Walker
Background: Up to 70% of people with multiple sclerosis (MS) experience cognitive impairment. Some remain cognitively intact despite advanced disease. Cognitive reserve (CR) theory postulates that individuals with higher levels of intellectual enrichment can tolerate more pathology than others before exhibiting cognitive impairment. Methods: Thirty-two individuals with early-phase relapsing-remitting MS with mild physical disability and disease duration less than 10 years and 32 controls were recruited...
July 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30150900/effects-of-external-perturbations-on-anticipatory-and-compensatory-postural-adjustments-in-patients-with-multiple-sclerosis-and-a-fall-history
#13
Shirin Tajali, Mina Rouhani, Mohammad Mehravar, Hossein Negahban, Elham Sadati, Ali E Oskouei
Background: Although previous studies have investigated postural adjustment mechanisms in patients with multiple sclerosis (MS), it seems that no study has yet investigated the relationship between anticipatory and compensatory postural adjustments (APAs and CPAs, respectively) and falls. Methods: Seventeen MS fallers, 17 MS nonfallers, and 15 controls were exposed to a series of expected and unexpected backward pull perturbations applied at the trunk level. The electrical activity of 12 leg and trunk muscles as well as center of pressure displacement were recorded...
July 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30150899/validation-of-the-2-minute-walk-test-with-the-6-minute-walk-test-and-other-functional-measures-in-persons-with-multiple-sclerosis
#14
David A Scalzitti, Kenneth J Harwood, Joyce R Maring, Susan J Leach, Elizabeth A Ruckert, Ellen Costello
Background: Persons with multiple sclerosis (MS) commonly have difficulty walking. The 6-Minute Walk Test (6MWT) assesses functional capacity but may be considered burdensome for persons with MS, especially those with higher disability levels. The 2-Minute Walk Test (2MWT) may be an alternative measure to the 6MWT. The purpose of this study was to investigate the validity of the 2MWT in persons with MS. Methods: Twenty-eight ambulatory persons with MS aged 18 to 64 years participated in this cross-sectional study...
July 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/30150898/-short-report-prevalence-of-cognitive-impairment-in-newly-diagnosed-relapsing-remitting-multiple-sclerosis
#15
Giulia DiGiuseppe, Mervin Blair, Sarah A Morrow
Background: Cognitive impairment is common in multiple sclerosis (MS) and can manifest early in the disease process, sometimes as early as the first demyelinating event. However, the frequency of cognitive impairment in a newly diagnosed MS population has not been evaluated comprehensively in a clinical population. We sought to examine the prevalence of cognitive impairment in relapsing-remitting MS (RRMS) within a year of diagnosis in a clinic where cognitive testing at diagnosis is part of routine practice...
July 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/29896053/editorial
#16
EDITORIAL
Francois Bethoux
No abstract text is available yet for this article.
May 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/29896052/somatic-symptoms-of-depression-and-anxiety-in-people-with-multiple-sclerosis
#17
Salene M W Jones, Rana Salem, Dagmar Amtmann
Background: People with multiple sclerosis (MS) are at increased risk for depression and anxiety. The symptoms of MS are often similar to the somatic or physical symptoms of depression and anxiety (fatigue, trouble concentrating). This study examined whether MS symptoms and effects biased the assessment of somatic symptoms of anxiety and depression. Methods: People with MS (n = 513) completed a survey about MS symptoms, treatments, and distress. The Patient Health Questionnaire-9 assessed depression, and the patient-report version of the Primary Care Evaluation of Mental Disorders assessed anxiety...
May 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/29896051/-case-report-osmotic-demyelination-syndrome-in-an-adolescent-with-neuromyelitis-optica
#18
Sarah Kariv, Kathleen Bateman
A 17-year-old girl presented with intractable vomiting due to area postrema involvement in the first presentation of seronegative neuromyelitis optica (NMO). During the course of her illness, she developed mild hyponatremia, and magnetic resonance imaging revealed abnormalities consistent with the co-occurrence of osmotic demyelination syndrome (ODS). This combination of imaging features is novel, and this case expands the spectrum of brain abnormalities seen in NMO and NMO spectrum disorders. It was suspected that NMO may predispose to ODS by causing astrocyte dysfunction involving aquaporin 4 water channels, which are implicated in both conditions...
May 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/29896050/-short-report-a-pilot-study-of-a-group-positive-psychology-intervention-for-patients-with-multiple-sclerosis
#19
Kaitlynne Leclaire, Audrey Cecil, Allison LaRussa, Fiona Stuart, Christopher C Hemond, Brian C Healy, Tanuja Chitnis, Howard Weiner, Jeff Huffman, Bonnie I Glanz
Background: Positive psychology uses targeted activities to increase the frequency and intensity of positive emotional experiences. Positive psychology interventions that increase positive constructs may facilitate adjustment and improve well-being in patients with multiple sclerosis (MS). The primary goal of this study was to assess the feasibility and acceptability of a 5-week group positive psychology intervention for patients with MS. In addition, we examined the utility of the group intervention to increase positive psychological constructs and health-related quality of life (HRQOL)...
May 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/29896049/social-cognitive-theory-correlates-of-physical-activity-in-inactive-adults-with-multiple-sclerosis
#20
Marcin Kacper Uszynski, Blathin Casey, Sara Hayes, Stephen Gallagher, Helen Purtill, Robert W Motl, Susan Coote
Background: There is a growing body of evidence that physical activity (PA) improves symptoms of multiple sclerosis (MS). Despite the benefits of PA, people with MS are relatively inactive compared with their healthy counterparts. This study investigated associations between social cognitive theory (SCT) constructs and energy expenditure (EE) as an objective measure of PA in a sample of inactive people with MS. Methods: Participants (n = 65) completed several questionnaires and were assessed using standardized outcome measures as part of a cross-sectional analysis of baseline data from a randomized controlled trial (Step it Up)...
May 2018: International Journal of MS Care
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