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International Journal of MS Care

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https://www.readbyqxmd.com/read/29070969/editorial
#1
Francois Bethoux
No abstract text is available yet for this article.
September 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/29070968/predictors-of-mortality-in-veterans-with-multiple-sclerosis-in-an-outpatient-clinic-setting
#2
Meheroz H Rabadi, Christopher E Aston
BACKGROUND: Examining factors that increase risk of death in veterans with multiple sclerosis (MS) may help reduce MS-related mortality. We sought to determine predictors of mortality in veterans with MS attending an outpatient clinic. METHODS: Review of electronic medical records of 226 veterans with MS regularly followed up from January 1, 2000, through December 31, 2014. RESULTS: Mortality at the end of the 15-year study period was 14%...
September 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/29070967/case-report-glatiramer-acetate-induced-serum-sickness
#3
Paul Ferguson
Multiple sclerosis (MS) is a central nervous system demyelinating disease with a prevalence of approximately 400,000 individuals in the United States. Glatiramer acetate is a frequently prescribed disease-modifying therapy used for the management of relapsing forms of the disease. A 40-year-old woman with relapsing-remitting MS presented with symptomatic concerns of vomiting, fever, diffuse rash, joint and low back pain, and distal lower-limb paresthesia and was subsequently admitted to the hospital for investigation and treatment...
September 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/29070966/psychometric-properties-of-a-clinical-strength-assessment-protocol-in-people-with-multiple-sclerosis
#4
Mark M Mañago, Jeffrey R Hebert, Margaret Schenkman
BACKGROUND: Strength training in people with multiple sclerosis (MS) is an important component of rehabilitation, but it can be challenging for clinicians to quantify strength accurately and reliably. This study investigated the psychometric properties of a clinical strength assessment protocol using handheld dynamometry and other objective, quantifiable tests for the lower extremities and trunk in people with MS. METHODS: This study determined discriminant validity between 25 participants with MS and 25 controls and between participants with MS who had higher versus lower disability; test-retest reliability across 7 to 10 days; and response stability...
September 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/29070965/validity-and-reliability-of-four-clinical-gait-measures-in-patients-with-multiple-sclerosis
#5
Susan E Bennett, Lacey E Bromley, Nadine M Fisher, Machiko R Tomita, Paulette Niewczyk
BACKGROUND: The gold standards for assessing ambulation are the Expanded Disability Status Scale (EDSS) and the Timed 25-Foot Walk (T25FW) test. In relation with these measures, we assessed the reliability and validity of four clinical gait measures: the Timed Up and Go (TUG) test, the Dynamic Gait Index (DGI), the 2-Minute Walk Test (2MWT), and the 6-Minute Walk Test (6MWT). Patient self-report of gait was also assessed using the 12-item Multiple Sclerosis Walking Scale (MSWS-12). METHODS: Individuals 20 years or older with a diagnosis of multiple sclerosis (MS) and an EDSS score of 2...
September 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/29070964/trigeminal-neuralgia-commonly-precedes-the-diagnosis-of-multiple-sclerosis
#6
Ahmad Fallata, Amber Salter, Tuula Tyry, Gary R Cutter, Ruth Ann Marrie
BACKGROUND: Trigeminal neuralgia (TN) is a well-recognized cause of facial pain in the general population, and multiple sclerosis (MS) accounts for some of these cases. However, the prevalence of TN in MS is poorly understood. We investigated the prevalence of TN and how often TN is the initial presentation of MS in a large MS cohort. METHODS: In 2009, we surveyed participants in the North America Research Committee on Multiple Sclerosis Registry regarding TN, including date of onset and pharmacologic and nonpharmacologic treatments used...
September 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/29070963/relationship-between-fatigability-and-perceived-fatigue-measured-using-the-neurological-fatigue-index-in-people-with-multiple-sclerosis
#7
Mayis Aldughmi, Jared Bruce, Catherine F Siengsukon
BACKGROUND: Understanding the relationship between perceived fatigue and performance fatigability could lead to more effective interventions to manage multiple sclerosis (MS)-related fatigue. However, the relationship between self-perceived fatigue measured using the Neurological Fatigue Index (NFI-MS) and performance fatigability in people with MS is unknown. We sought to explore the relationship between the NFI-MS and performance fatigability in people with MS. METHODS: Fifty-two participants (mean ± SD age, 46...
September 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/29070962/mindfulness-in-motion-for-people-with-multiple-sclerosis-a-feasibility-study
#8
Rachel M Gilbertson, Maryanna D Klatt
BACKGROUND: Mindfulness in Motion is an 8-week mindfulness-based intervention that uses yoga movement, mindfulness meditation, and relaxing music. This study examined the feasibility of using Mindfulness in Motion in people with multiple sclerosis (MS) and the effect of this program on stress, anxiety, depression, fatigue, and quality of life in people with MS. METHODS: Twenty-two people with MS completed the 8-week mindfulness program as well as assessments 1 week before and after the intervention...
September 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28835747/editorial
#9
EDITORIAL
Francois Bethoux
No abstract text is available yet for this article.
July 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28835746/effect-of-cognitive-demand-on-functional-mobility-in-ambulatory-individuals-with-multiple-sclerosis
#10
Marcia Aparecida Ciol, Patricia Noritake Matsuda, Seema Rani Khurana, Melissa Jaclyn Cline, Jacob Jonathan Sosnoff, George Howard Kraft
BACKGROUND: As disease progresses, cognitive demands may affect functional mobility in individuals with multiple sclerosis (MS). The Timed Up and Go (TUG) test assesses functional mobilityin populationssuch as MS. A cognitive-demanding task can be added to the TUG test to assess its effect on functional mobility. METHODS: People with MS (n = 52) and controls (n = 57) performed three versions of the TUG test: TUG alone (TUG-alone), TUG plus reciting the alphabet (TUG-alpha), and TUG plus subtracting numbers by 3s (TUG-3s)...
July 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28835745/cultural-adaptation-validity-and-factor-structure-of-the-jalowiec-coping-scale-in-iranian-women-with-multiple-sclerosis-which-coping-strategies-are-most-common-and-effective
#11
Mohsen Saffari, Hormoz Sanaeinasab, Mahrokh Hashempour, Amir H Pakpour, Jesus F Lovera, Saad Al Shohaib
BACKGROUND: The aims of this study were to evaluate the Jalowiec Coping Scale (JCS) psychometrically in Iranian women with multiple sclerosis (MS) and to identify the most frequent and efficacious coping strategies. METHODS: A total of 306 women with MS participated in a cross-sectional study. A demographics questionnaire, the JCS, and the Perceived Stress Scale were administered. Forward-backward translation was used to achieve a Persian version of the scale. Cronbach α and test-retest were assessed for reliability...
July 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28835744/depression-and-age-at-first-neurology-appointment-associated-with-receipt-of-behavioral-medicine-services-within-1-year-in-a-multiple-sclerosis-population
#12
Benjamin Greenberg, Youran Fan, Lucille Carriere, Amy Sullivan
BACKGROUND: Patients with multiple sclerosis (MS) newly seen by a neurologist may benefit from early psychological intervention owing to the reciprocal relationship between stress and disease progression. However, it is uncertain what factors contribute to patients' receiving these services. METHODS: Logistic regression analysis of prospectively gathered data evaluated how demographic and disease characteristics and emotional/physical health factors contributed to referral to receive behavioral medicine (BM) services within 1 year of their first neurology appointment at the Mellen Center for Multiple Sclerosis at the Cleveland Clinic...
July 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28835743/how-beliefs-about-bladder-dysfunction-among-health-care-professionals-influence-clinical-practice-development-perspectives-of-allied-health-professionals-nurses-and-managers
#13
Catherine Browne, Maria Kehoe, Nancy Salmon
BACKGROUND: Bladder dysfunction can affect up to 75% of people with multiple sclerosis (MS) on several important life domains. It is a multifaceted problem that remains underdiagnosed by health-care professionals. The aims of this study were to understand the perceptions of Irish health-care professionals regarding bladder dysfunction and to explore current service provision for people with MS. METHODS: Two focus groups, three dyadic interviews, and one semistructured interview with 14 health-care professionals lasting up to 90 minutes were audio-recorded...
July 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28835742/associations-between-bladder-dysfunction-and-falls-in-people-with-relapsing-remitting-multiple-sclerosis
#14
Jaime E Zelaya, Charles Murchison, Michelle Cameron
BACKGROUND: Bladder dysfunction and falls are common in people with multiple sclerosis (MS), but associations between these problems are unclear. We sought to clarify the association between specific types of bladder dysfunction and prospectively recorded falls in people with MS. METHODS: Fifty-one people aged 18 to 50 years with relapsing-remitting MS and mild-to-moderate disability (Expanded Disability Status Scale score ≤6.0) completed a self-report questionnaire regarding urinary incontinence, urgency, and frequency at baseline and then prospectively recorded their falls daily for 3 months using fall calendars...
July 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28835741/preferences-for-multiple-sclerosis-treatments-using-a-discrete-choice-experiment-to-examine-differences-across-subgroups-of-us-patients
#15
Carol Mansfield, Nina Thomas, David Gebben, Maria Lucas, A Brett Hauber
BACKGROUND: The growing number of treatments for relapsing multiple sclerosis (MS) provides opportunities to consider patient preferences in treatment decisions. METHODS: We designed a Web-based, discrete-choice experiment survey to analyze treatment preferences in patients with relapsing-remitting MS (RRMS). The survey presented hypothetical MS treatments defined by six attributes: risk of MS progression, time between relapses, risk of serious infection, treatment-related flu-like symptoms and gastrointestinal symptoms, and route and frequency of administration...
July 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28835740/women-s-and-men-s-differing-experiences-of-health-lifestyle-and-aging-with-multiple-sclerosis
#16
Michelle Ploughman, Katie Collins, Elizabeth M Wallack, Michael Monks, Nancy Mayo
BACKGROUND: The growing population of older people with multiple sclerosis (MS) has led to more interest in understanding factors associated with healthy aging. We aimed to determine whether older women and men with MS have different health and lifestyle behaviors and whether there are sex differences in contributors to perceived health. METHODS: Data were obtained from a postal survey involving 743 Canadians older than 55 years with MS for at least 20 years. Sex differences in health, lifestyle, mood, and socioeconomics were examined using analysis of variance...
July 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28603466/editorial
#17
EDITORIAL
Francois Bethoux
No abstract text is available yet for this article.
May 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28603465/spinal-cord-as-an-adjunct-to-brain-magnetic-resonance-imaging-in-defining-no-evidence-of-disease-activity-in-multiple-sclerosis
#18
Subhash Tummala, Tarun Singhal, Vinit V Oommen, Gloria Kim, Fariha Khalid, Brian C Healy, Rohit Bakshi
Background: Monitoring patients with multiple sclerosis (MS) for “no evidence of disease activity” (NEDA) may help guide disease-modifying therapy (DMT) management decisions. Whereas surveillance brain magnetic resonance imaging (MRI) is common, the role of spinal cord monitoring for NEDA is unknown. Objective: To evaluate the role of brain and spinal cord 3T MRI in the 1-year evaluation of NEDA. Methods: Of 61 study patients (3 clinically isolated syndrome, 56 relapsing-remitting, 2 secondary progressive), 56 (91...
May 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28603464/reliability-and-validity-of-the-computerized-dynamic-posturography-sensory-organization-test-in-people-with-multiple-sclerosis
#19
Jeffrey R Hebert, Mark M Manago
BACKGROUND: People with multiple sclerosis (MS) frequently have impaired postural control (balance). Psychometric properties of clinical tests of balance for individuals with MS, including the computerized dynamic posturography sensory organization test (CDP-SOT), are poorly understood. This study aimed to determine the reliability and discriminant validity of the CDP-SOT in people with MS. METHODS: The CDP-SOT was performed on 30 participants with MS. A 2-week-interval, repeated-measures (sessions 1 and 2) design was implemented to investigate test-retest reliability of the CDP-SOT and the ability of the CDP-SOT to discriminate between participants with lower versus higher disability...
May 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28603463/case-report-two-cases-of-nicolau-syndrome-associated-with-glatiramer-acetate
#20
Dorlan J Kimbrough, Scott D Newsome
We report two cases of Nicolau syndrome (embolia cutis medicamentosa), a rare complication of injectable medications, both associated with the administration of 20 mg of subcutaneous glatiramer acetate. Both patients required surgical debridement and were subsequently treated conservatively without additional complications. Patient 1 opted to discontinue disease-modifying therapy. Patient 2 continued glatiramer acetate therapy without complications by using other injection sites. These cases highlight the need for prompt investigation of new unusual skin lesions in patients receiving injectable multiple sclerosis treatments (regardless of length of treatment and previous minor cosmetic concerns) and illustrate the clinical distinction between Nicolau syndrome and drug-induced skin necrosis...
May 2017: International Journal of MS Care
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