Diya Sanjeev, Mejo George, Levin John, Athira Perunelly Gopalakrishnan, Pahal Priyanka, Spoorthi Mendon, Tanuja Yandigeri, Mahammad Nisar, Muhammad Nisar, Saptami Kanekar, Rex Devasahayam Arokia Balaya, Rajesh Raju
Homeodomain-interacting protein kinase 1 (HIPK1) is majorly found in the nucleoplasm. HIPK1 is associated with cell proliferation, tumor necrosis factor-mediated cellular apoptosis, transcription regulation, and DNA damage response, and thought to play significant roles in health and common diseases such as cancer. Despite this, HIPK1 remains an understudied molecular target. In the present study, based on a systematic screening and mapping approach, we assembled 424 qualitative and 44 quantitative phosphoproteome datasets with 15 phosphosites in HIPK1 reported across multiple studies...
March 18, 2024: Omics: a Journal of Integrative Biology