journal
https://read.qxmd.com/read/38527794/folic-acid-in-women-with-epilepsy-prescribing-advice
#1
EDITORIAL
Michael Owen Kinney, John J Craig, Norman Delanty
No abstract text is available yet for this article.
March 25, 2024: Practical Neurology
https://read.qxmd.com/read/38508722/optokinetic-nystagmus-six-practical-uses
#2
JOURNAL ARTICLE
David Edward Hale, Stephen Reich, Dan Gold
Optokinetic nystagmus (OKN) is a reflexive eye movement in response to movement of the viewer's visual environment that consists of a slow phase eye movement in the direction of the stimulus followed by a quick phase in the opposite direction. When tested at the bedside, the slow phases represent smooth pursuit, while the quick phases represent saccades. Normally, OKN is conjugate and symmetric (horizontally and vertically). Abnormalities in the optokinetic response can provide diagnostic and localising value...
March 20, 2024: Practical Neurology
https://read.qxmd.com/read/38508721/the-elements-of-eloquence-by-mark-forsyth
#3
JOURNAL ARTICLE
Charles J S Nye
No abstract text is available yet for this article.
March 20, 2024: Practical Neurology
https://read.qxmd.com/read/38508720/progressive-multifocal-leucoencephalopathy-isolated-to-the-brainstem-and-cerebellum
#4
JOURNAL ARTICLE
Denison Alves Pedrosa, Luis Filipe de Souza Godoy, André Luiz Guimarães de Queiroz, Carla Renata Aparecida Vieira Stella, Rodrigo B Thomaz
No abstract text is available yet for this article.
March 20, 2024: Practical Neurology
https://read.qxmd.com/read/38499334/restricting-valproate-prescribing-in-men-wisdom-or-folly
#5
EDITORIAL
Samuel F Berkovic, Emilio Perucca
No abstract text is available yet for this article.
March 18, 2024: Practical Neurology
https://read.qxmd.com/read/38499333/we-need-to-talk-about-brain-donation
#6
EDITORIAL
Martin R Turner
No abstract text is available yet for this article.
March 18, 2024: Practical Neurology
https://read.qxmd.com/read/38485227/end-of-life-care
#7
JOURNAL ARTICLE
Arani Nitkunan
My 96-year-old aunt taught me so much about end-of-life care. As doctors dealing with long-term neurological conditions, our relationships with patients over many years should enable us to be much more involved in helping them make decisions about the ceilings of treatment.
March 14, 2024: Practical Neurology
https://read.qxmd.com/read/38485226/-a-ray-of-darkness-by-margiad-evans
#8
JOURNAL ARTICLE
Yasmin Zid, Phil E M Smith
No abstract text is available yet for this article.
March 14, 2024: Practical Neurology
https://read.qxmd.com/read/38485225/kennedy-s-disease
#9
JOURNAL ARTICLE
Helen Devine, Matthew Solomons, Luca Zampedri, Michael G Hanna, Carlo Rinaldi, Pietro Fratta, Dipa Jayaseelan
A 57-year-old man developed worsening early morning headaches, muscle cramps and falls over 12 months. He had widespread fasciculation and was diagnosed with motor neurone disease, and treated with nocturnal hypoventilation. Based on this diagnosis, he made significant personal and financial decisions including retiring and selling his house. He subsequently developed a lump in his right breast and was found to have gynaecomastia. This triggered genetic testing for Kennedy's disease leading to the correct diagnosis...
March 14, 2024: Practical Neurology
https://read.qxmd.com/read/38471756/simultaneous-horner-s-syndrome-with-anhidrosis-and-facial-nerve-palsy-in-internal-carotid-artery-dissection
#10
JOURNAL ARTICLE
Tharuka Herath, Tsneem H S Mbydeen, Savindu Alagoda, May Saleh, Leena Naidu, Sunil Wimalaratna
No abstract text is available yet for this article.
March 12, 2024: Practical Neurology
https://read.qxmd.com/read/38453474/dopa-responsive-dystonia-and-paroxysmal-dystonic-attacks-associated-with-atp1a3-gene-variant
#11
JOURNAL ARTICLE
Míriam Carvalho Soares, Jacy Bezerra Parmera, Marcos Eugênio Ramalho Bezerra, Rubens Gisbert Cury
An 18-year-old man had episodes of severe generalised dystonia, from aged 7 months and becoming progressively more frequent. He also had gradually developed interictal limb dystonia. He was initially diagnosed with paroxysmal kinesigenic dyskinesia but he did not improve with several medications. A levodopa trial led to levodopa-induced dyskinetic movements. However, a lower titration of 25 mg of levodopa two times per day substantially improved his motor features and quality of life. Laboratory investigations and MR scans of the brain were unremarkable...
March 7, 2024: Practical Neurology
https://read.qxmd.com/read/38453473/hepatic-encephalopathy-a-neurologist-s-perspective
#12
REVIEW
Edward Needham, Gwilym Webb
Liver disease is increasingly common, estimated to affect over 25% of the world's population. Failure of the liver to maintain a normal metabolic milieu leads to impaired brain function (hepatic encephalopathy), and conditions that cause liver disease can themselves predispose to neurological disease. As neurologists' involvement with the acute take increases, it is important that we are familiar with the neurological complications of liver disease, their investigation and management, and to know which other neurological diseases occur in this patient population...
March 7, 2024: Practical Neurology
https://read.qxmd.com/read/38423756/paroxysmal-dysarthria-ataxia-syndrome
#13
JOURNAL ARTICLE
Marija Cauchi, Janice Abela, Nicola Dingli, Norbert Vella
Paroxysmal dysarthria ataxia syndrome presents with recurrent, brief, stereotyped events of dysarthria, limb clumsiness, unsteady gait and vertigo or dizziness that can occur in association with lesions in the midbrain. We describe a case of a woman presenting with paroxysmal dysarthria and ataxia secondary to a midbrain lesion, treated successfully with carbamazepine.
February 29, 2024: Practical Neurology
https://read.qxmd.com/read/38423755/spinal-dural-arteriovenous-fistula
#14
JOURNAL ARTICLE
Alexander Berry-Noronha, Natasha Ironside, Wayne Collecutt, Ozayr Ameen, Teddy Y Wu
No abstract text is available yet for this article.
February 29, 2024: Practical Neurology
https://read.qxmd.com/read/38423754/encephalitis-associated-with-anti-mglur5-antibodies
#15
JOURNAL ARTICLE
Denison Alves Pedrosa, João Henrique Fregadolli Ferreira, Rene Gleizer, Rafael Bernhart Carra, Rachel Marin de Carvalho, Verena Endmayr, Romana Hoftberger, Lívia Almeida Dutra
A 30-year-old woman had 5 days of visual hallucinations, nystagmus, memory impairment and mutism. On examination, she was disorientated with reduced attention span, gaze-evoked nystagmus, paratonia and abnormal frontal reflexes. Cerebrospinal fluid (CSF) showed 80 cells, protein 0.41 g/L and glucose 3.2 mmol/L (plasma glucose 5.0 mmol/L). MR scan of the brain showed involvement of limbic and extra-limbic regions and brainstem. Commercial cell-based assays were negative, but tissue-based assays showed neuropil staining, and cell-based assays for anti-metabotropic glutamate receptor 5 (mGluR5) antibodies were positive in serum and CSF...
February 29, 2024: Practical Neurology
https://read.qxmd.com/read/38423753/shrinking-lung-syndrome-mimicking-diaphragmatic-palsy-in-systemic-lupus-erythematosus
#16
JOURNAL ARTICLE
Shivam Mirg, Animesh Das, Awadh Kishor Pandit, M C Sharma, Achal K Srivastava
A 25-year-old woman presented with 1 year of progressive orthopnoea, initially explained as bilateral diaphragmatic paresis caused by seronegative myasthenia gravis. She required assisted ventilation and received pyridostigmine and corticosteroids. She had minimal (particularly proximal) symmetrical tetraparesis with apparent bilateral diaphragmatic weakness, but had normal sensation. Further investigation suggested an overlap myositis with shrinking lung syndrome from systemic lupus erythematosus. She improved following immunosuppression with pulse corticosteroids and rituximab, and at 3 months no longer needed bilevel positive airway pressure support...
February 29, 2024: Practical Neurology
https://read.qxmd.com/read/38408862/fertility-treatment-for-people-with-epilepsy
#17
JOURNAL ARTICLE
Ginette Moores, Kimberly Liu, Aleksandra Pikula, Esther Bui
Fertility treatment, including assisted reproductive technology (ART), is increasingly used. Sex hormones influence seizure control as well as interacting with antiseizure medications, and so the hormonal manipulation involved in fertility treatments has direct implications for people with epilepsy. Here, we summarise the various fertility treatments and consider their important influences on epilepsy care. While early observations raised concerns about seizure exacerbation associated with ART, there are limited data to guide best practice in people with epilepsy, and further research is needed...
February 26, 2024: Practical Neurology
https://read.qxmd.com/read/38388433/primary-neurolymphomatosis-diagnosed-by-spinal-nerve-root-biopsy
#18
JOURNAL ARTICLE
Samantha Louise Saunders, Samantha M Giang, Sangruthai Sriweerawanidchakun, Anna Schutz
Primary neurolymphomatosis is the direct infiltration of lymphomatous neoplastic cells into nerve roots and/or peripheral nerves. A 67-year-old man had a 24-month history of progressive and severe left lower limb neuropathic pain, ipsilateral ankle dorsiflexion weakness and gait disturbance. Gadolinium-enhanced MRI showed thickening and enhancement of the cauda equina, L5, S1 and S2 nerve roots. 18 Fluorodeoxyglucose positron emission tomography showed concordant hypermetabolism. L5 nerve root biopsy confirmed diffuse large B-cell lymphoma...
February 22, 2024: Practical Neurology
https://read.qxmd.com/read/38378269/neurological-manifestations-in-malignant-melanoma
#19
JOURNAL ARTICLE
H M M T B Herath, Nadiene G Lutchman, May Saleh, Leena Naidu, Shyama Balasuriya Alagoda, Stefen Brady, Sunil Wimalaratna
No abstract text is available yet for this article.
February 20, 2024: Practical Neurology
https://read.qxmd.com/read/38378268/new-onset-seizure-and-acute-encephalopathy
#20
JOURNAL ARTICLE
Lin-Yuan Zhang, Xia Liu, Yun-Cheng Wu, Guo-Dong Wang
No abstract text is available yet for this article.
February 20, 2024: Practical Neurology
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