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Spine Journal: Official Journal of the North American Spine Society

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https://www.readbyqxmd.com/read/29906618/treatment-outcomes-of-17-patients-with-atypical-spinal-meningioma-including-4-with-metastases-a-retrospective-observational-study
#1
Sung Hyun Noh, Kyung Hyun Kim, Dong Ah Shin, Jeong Yoon Park, Seong Yi, Sung Uk Kuh, Keung Nyun Kim, Dong Kyu Chin, Keun Su Kim, Do Heum Yoon, Yong Eun Cho
BACKGROUND CONTEXT: Because of the scarcity of atypical spinal meningioma, there is a lack of research on this type of tumor or its associated metastases. PURPOSE: The aim of this study was to investigate the biological behavior of atypical spinal meningioma and identify its prognostic factors by reviewing surgical and clinical outcomes of patients with these tumors. STUDY DESIGN/SETTING: A retrospective chart review was performed. PATIENT SAMPLE: We retrospectively reviewed the data from all patients who underwent spinal cord tumor excision between 1994 and 2017...
June 12, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29906617/the-effect-of-psychosocial-measures-of-resilience-and-self-efficacy-in-patients-with-neck-and-lower-back-pain
#2
Shaan A Ahmed, Govind Shantharam, Adam E M Eltorai, Davis A Hartnett, Avi Goodman, Alan H Daniels
BACKGROUND CONTEXT: Psychosocial risk factors may predispose to progression of back and neck pain to chronic pain or disability. Resilience (the ability to recover from stress) and pain self-efficacy (confidence that one can perform daily activities despite pain) are important psychometric properties shown to affect health and illness. PURPOSE: To examine the relationships among resilience, pain self-efficacy, and disability in spine patients. STUDY DESIGN/SETTING: Prospective, single-center orthopedic spine clinic...
June 12, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29906616/anticipatory-and-compensatory-postural-adjustments-in-people-with-low-back-pain-a-systematic-review-and-meta-analysis
#3
REVIEW
Michael F Knox, Lucy S Chipchase, Siobhan M Schabrun, Rick J Romero, Paul W M Marshall
BACKGROUND CONTEXT: Despite altered anticipatory (APAs) and compensatory postural adjustments (CPAs) being hypothesized to contribute to the onset and persistence of low back pain (LBP), results from studies comparing people with and without LBP are conflicting. PURPOSE: This systematic review aimed to determine whether anticipatory (APAs) or compensatory postural adjustments (CPAs) are altered in the presence of acute and chronic low back pain (LBP). STUDY DESIGN: A systematic review of studies was carried out...
June 12, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29890263/long-term-outcome-of-treatment-of-vertebral-body-hemangiomas-with-direct-ethanol-injection-and-short-segment-stabilization
#4
P Sarat Chandra, Pankaj Singh, Rajender K, Deepak Agarwal, Vivek Tandon, S S Kale, Chitra Sarkar
BACKGROUND: Vertebral body (VH) hemangiomas with myelopathy are difficult to manage. OBJECTIVE: To evaluate the role of intra-operative ethanol embolization, surgical decompression and instrumented short segment fusion in VH with myelopathy and long-term outcome (>24 months). METHODS: Prospective study: Symptomatic VH with cord compression with myelopathy. Excluded: pathological fractures, and/or deformity or multi-level pathologies. Surgery consisted of intra-operative bilateral pedicular absolute alcohol (<1% hydrated ethyl alcohol) injection, laminectomy and cord decompression at the level of pathology followed by a short segment instrumented fusion using pedicle screws...
June 8, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29886166/attenuation-of-the-degenerative-effects-of-endothelin-1-on-cartilaginous-endplate-cells-by-the-endothelin-receptor-antagonist-bq-123-via-the-wnt-%C3%AE-catenin-signaling-pathway
#5
Wei Yuan, Zhen-Xi Li, Cheng-Long Zhao, Tian-Hui Hou, Si-Wang Hu, Wei-Bo Liu, Feng-Lai Yuan, Jian-Ru Xiao
BACKGROUND: Context: Endothelin-1 (ET-1) is an inflammatory mediator associated with cartilage endplate (CEP) degeneration in the intervertebral disc. SOX9 is down-regulated during CEP degeneration, along with its targets, collagen II and aggrecan. Wnt/β-catenin signaling is associated with CEP degeneration and a downstream target of SOX9; however, the precise mechanism of CEP degeneration and the role of ET-1 are largely unknown. PURPOSE: The purpose of the study was to evaluate the influence of the endothelin A receptor antagonist, BQ-123, on ET-1-induced effects on cartilaginous endplate cells (CECs) associated with CEP degeneration via the Wnt/β-catenin signaling pathway...
June 7, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29886165/surgical-versus-non-surgical-management-for-type-ii-odontoid-fractures-in-the-elderly-population-a-systematic-review
#6
REVIEW
Deep P Sarode, Andreas K Demetriades
BACKGROUND: Odontoid process fractures, of which type II constitute the majority, are an increasingly important cause of morbidity and mortality in the elderly population. The incidence of geriatric type II fractures is steadily increasing in line with the ageing population. However, the decision between surgical and non-surgical intervention for type II fractures in the elderly remains controversial. PURPOSE: To synthesise the current published literature comparing outcomes following surgical and non-surgical interventions for type II odontoid fractures in the elderly population (≥65 years old)...
June 7, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29886164/effect-of-disc-degeneration-on-the-mechanical-behavior-of-the-human-lumbar-spine-a-probabilistic-finite-element-study
#7
Maxim Bashkuev, Sandra Reitmaier, Hendrik Schmidt
BACKGROUND CONTEXT: Intervertebral disc degeneration has been subject to numerous in vivo and in vitro investigations and numerical studies during recent decades, reporting partially contradictory findings. However, most of the previous studies were limited in the number of specimens investigated and, therefore, could not consider the vast variety of the specimen geometries, which are likely to strongly influence the mechanical behavior of the spine. PURPOSE: To complement the understanding of the mechanical consequences of disc degeneration, while considering natural variations in the major spinal geometrical parameters...
June 7, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29886163/dynamic-adaptation-of-vertebral-endplate-and-trabecular-bone-following-annular-injury-in-a-rat-model-of-degenerative-disc-disease
#8
Tristan Maerz, Michael Newton, Abigail A Marek, Michael Planalp, Kevin Baker
BACKGROUND/CONTEXT: Degenerative disc disease (DDD) is associated with longitudinal remodeling of paravertebral tissues. While chronic vertebral changes in advanced stages of DDD are well-studied, very little data exists on acute vertebral bone remodeling at the onset and progression of DDD. PURPOSE: To longitudinally characterize bony remodeling in a rodent model of disc injury-induced DDD. STUDY DESIGN/SETTING: In vivo animal study involving a rat annulus fibrosus injury model of DDD...
June 7, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29886162/reoperation-rates-and-risk-factors-for-revision-4-years-after-dynamic-stabilization-of-the-lumbar-spine
#9
A C Rienmüller, S M Krieg, F A Schmidt, E L Meyer, B Meyer
BACKGROUND CONTEXT: The concept of dynamic stabilization (DS) of the lumbar spine for treatment of degenerative instability has been introduced almost two decades ago. DS follows the principle of controlling movement in the coronal plane by providing load transfer of the spinal segment without fusion and at the same time reducing side effects such as adjacent segment disease (ASD). So far only little is known about revision rates after DS due to adjacent segment disease (ASD) and screw loosening (SL)...
June 7, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29864546/complications-and-reoperations-after-surgery-for-647-patients-with-spine-metastatic-disease-%C3%A2-%C3%A2-%C3%A2
#10
Nuno Rui Paulino Pereira, Paul T Ogink, Olivier Q Groot, Marco L Ferrone, Francis J Hornicek, C N van Dijk, J A M Bramer, Joseph H Schwab
BACKGROUND CONTEXT: Postoperative morbidity may offset the potential benefits of surgical treatment for spine metastatic disease; hence, risk factors for postoperative complications and reoperations should be taken into considerations during surgical decision-making. In addition, it remains unknown whether complications and reoperations shorten these patients' survival. PURPOSE: We aimed to describe and identify factors associated with having a complication within 30 days of index surgery as well as factors associated with having a subsequent reoperation...
June 1, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29864545/an-empiric-analysis-of-5-counter-measures-against-surgical-site-infections-following-spine-surgery-a-pragmatic-approach-and-review-of-the-literature
#11
Marko Tomov, Nathan Wanderman, Elie Berbari, Bradford Currier, Michael Yaszemski, Ahmad Nassr, Paul Huddleston, Mohamad Bydon, Brett Freedman
BACKGROUND CONTEXT: Surgical site infections (SSI) following spine surgery are debilitating complications to patients and costly to the healthcare system. PURPOSE: Review the impact and cost effectiveness of five SSI prevention interventions on SSI rates in an orthopaedic spine surgery practice at a major quaternary healthcare system over a 10-year period. STUDY DESIGN: Retrospective observational study. PATIENT SAMPLE: All of the surgical patients of five spine surgeons in our department over a 10-year period were included in this study...
June 1, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29864544/discharge-to-inpatient-facilities-after-lumbar-fusion-surgery-is-associated-with-increased-postoperative-venous-thromboembolism-and-readmissions
#12
Sariah Khormaee, Andre M Samuel, William W Schairer, Peter B Derman, Alexander S McLawhorn, Michael C Fu, Todd J Albert
BACKGROUND CONTEXT: Post-discharge care is a significant source of cost variability after posterior lumbar fusion surgery. However, there remains limited evidence associating post-discharge inpatient services and improved postoperative outcomes, despite the high cost of these services. PURPOSE: To determine the association between post-hospital discharge to inpatient care facilities and postoperative complications. STUDY DESIGN/SETTING: A retrospective review of all 1- to 3-level primary posterior lumbar fusion cases in the 2010-2014 National Surgical Quality Improvement Program registry was conducted...
June 1, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29859351/the-impact-of-prophylactic-intraoperative-vancomycin-powder-on-microbial-profile-antibiotic-regimen-length-of-stay-and-reoperation-rate-in-elective-spine-surgery
#13
Zachary J Grabel, Allison Boden, Dale N Segal, Stephanie Boden, Andrew H Milby, John G Heller
BACKGROUND CONTEXT: There is growing concern that the microbial profile of surgical site infection (SSI) in the setting of prophylactic vancomycin powder may favor more resistant and uncommon organisms. PURPOSE: To demonstrate the impact of prophylactic intraoperative vancomycin powder on microbial profile, antibiotic regimen, length of stay, and reoperation rate in spine surgical site infection. STUDY DESIGN/SETTING: Retrospective cohort study...
May 30, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29859350/the-cost-effectiveness-of-minimally-invasive-spine-surgery-in-the-treatment-of-adult-degenerative-scoliosis-a-comparison-of-trans-psoas-and-open-techniques
#14
Ganesh Swamy, Elena Lopatina, Ken C Thomas, Deborah A Marshall, Herman S Johal
INTRODUCTION: Surgical treatment improves quality of life in patients with adult degenerative scoliosis (ADS). However, open ADS surgeries are complex, large magnitude operations associated with a high rate of complications. The lateral trans-psoas interbody fusion technique is a less invasive alternative to open ADS surgery, but less invasive techniques tend to be more expensive. The objective of this study was to evaluate the cost-effectiveness of the trans-psoas technique for patients with ADS over a 12-month time horizon from a public payer perspective...
May 30, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29859349/elevated-glycohemoglobin-hba1c-is-associated-with-low-back-pain-in-non-overweight-diabetics
#15
Alexander Real, Chierika Ukogu, Divya Krishnamoorthy, Nicole Zubizarreta, Samuel K Cho, Andrew C Hecht, James C Iatridis
BACKGROUND CONTEXT: Low back pain (LBP) is a common complaint in clinical practice of multifactorial origin. Although obesity has been thought to contribute to LBP primarily by altering the distribution of mechanical loads on the spine, the additional contribution of obesity-related conditions such as diabetes mellitus (DM) to LBP has not been thoroughly examined. PURPOSE: To determine if there is a relationship between DM and LBP that is independent of BMI in a large cohort of adult survey participants...
May 30, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29802889/surgical-treatment-of-early-onset-idiopathic-scoliosis-in-the-united-states-a-trend-analysis-of-15-years-1997-2012
#16
Tarush Rustagi, Swamy Kurra, Katherine Sullivan, Ravi Dhawan, William F Lavelle
BACKGROUND CONTEXT: Early onset scoliosis is a challenging problem that is defined as a curvature of the spine of more than 10 degrees identified in a child less than 10 years. Early onset idiopathic scoliosis (EOIS) can cause substantial morbidity and may require surgical intervention. PURPOSE: The aim of the current study was to identify the trends of EOIS type of surgeries, length of hospital stay, in-hospital complications and total inpatient admission charges over a 15-year study period in United States from 1997-2012...
May 23, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29800710/induced-lumbosacral-radicular-symptom-referral-patterns-a-descriptive-study
#17
Michael B Furman, Stephen C Johnson
BACKGROUND CONTEXT: Lumbosacral radicular symptoms are commonly evaluated in clinical practice. Level specific diagnosis is crucial for management. Clinical decisions are often made by correlating a patient's symptom distribution and imaging with sensory dermatomal maps. It is not uncommon for patients to describe non-dermatomal symptom patterns or for imaging to demonstrate pathology at levels not predicted by a dermatomal map. These observations suggest that the referred symptom distribution from lumbosacral nerve root provocation is different from dermatomal maps...
May 22, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29800709/a-novel-in-vivo-large-animal-model-of-lumbar-spinal-joint-degeneration
#18
Tian Wang, Matthew H Pelletier, Chris Christou, Rema Oliver, Ralph J Mobbs, William R Walsh
BACKGROUND CONTEXT: Degenerative disc disease (DDD) is a common, widespread socio-economic problem. Appropriate large animal models of DDD are required for improved understanding and to serve as pre-clinical test beds for therapeutic strategies PURPOSE: Evaluate the effects of short and medium duration immobilization on the sheep lumbar intervertebral disc and facet joints, to establish a large animal model for DDD research. STUDY DESIGN: An in vivo sheep model evaluating the effect of short and medium term immobilization on disc degeneration...
May 22, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29800708/five-year-follow-up-of-clinical-and-radiological-outcomes-of-lp-esp-elastomeric-lumbar-total-disc-replacement-in-active-patients
#19
Jean-Yves Lazennec, Jean-Patrick Rakover, Marc-Antoine Rousseau
BACKGROUND CONTEXT: The surgical treatment of degenerative disc disease (DDD) at the lumbar spine may involve fusion. TDR is an alternative treatment to avoid fusion related adverse events, specifically adjacent segment disease. New generation of elastomeric non-articulating devices have been developed to more effectively replicate the shock absorption and flexural stiffness of native disc. PURPOSE: To report 5 years clinical and radiographic outcomes, range of motion and position of the center of rotation after a viscoelastic lumbar total disc replacement (TDR)...
May 22, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29800707/patient-reported-allergies-predict-postoperative-outcomes-and-psychosomatic-markers-following-spine-surgery
#20
David D Xiong, Wenda Ye, Roy Xiao, Jacob A Miller, Thomas E Mroz, Michael P Steinmetz, Sean J Nagel, Andre G Machado
BACKGROUND CONTEXT: Prior studies have shown that patient-reported allergies can be prognostic of poorer postoperative outcomes. PURPOSE: To investigate the correlation between self-reported allergies and outcomes after cervical or lumbar spine surgery. STUDY DESIGN/SETTING: Retrospective cohort study at a single tertiary-care institution. PATIENT SAMPLE: All patients undergoing cervical or lumbar spine surgery from 2009-2014...
May 22, 2018: Spine Journal: Official Journal of the North American Spine Society
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