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Asian Pacific Journal of Cancer Prevention: APJCP

Shin Young Lee, Eunice E Lee
Background: Colorectal cancer (CRC) is one of the most common cancers among Korean Americans (KAs) and their CRC screening rates are low. To raise the rates of CRC screening among KAs, it is necessary to improve our understanding of factors that influence their CRC screening behaviors. This study examined socio-demographics, access to health care, health and cultural beliefs, and behaviors about the fecal occult blood test (FOBT) for CRC screening among KAs aged 50 and older. Methods: Based on the health belief model, the cultural assessment model for health, and the Powe fatalism model, this study measured socio-demographics (age, gender, years in the U...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Natthawut Kaewpitoon, Soraya J Kaewpitoon, Thirayu Meererksom, Siwawich Chan-Aran, Wararat Sangwalee, Jirawoot Kujapun, Jun Norkaew, Jirayut Chuatanam, Sukanya Ponpimai, Mali Pothipim, Natnapa Padchasuwan, Taweesak Tongtawee, Likit Matrakool, Sukij Panpimanmas, Ryan A Loyd, Parichart Wakkhuwatthapong
The carcinogenic liver fluke, Opisthorchis viverrini, is a serious health problem in Southeast Asia where infection is associated with cholangiocarcinoma, a major cause of death in Thailand. This cross-sectional study aimed to screen for O. viverrini infection among a Thai rural population of 560 individuals from Nakhon Ratchasima, Khonkaen, and Chaiyaphum provinces with a verbal screening test with a mobile application (OvApp). Faecal samples were also processed with a mini-parasep sf parasite faecal concentrator...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Sonia Rezaei, Fariborz Faeghi, Mohammad Samadian, Babak Shekarchi
Background: This study aims to investigate the ability of BSMI, to preoperative evaluation of tumor adhesion to adjacent brain tissue in patients with meningioma and comparing this method to the width of edema around tumor, using surgery findings as the reference standard. Methods: Thirty patients with meningioma brain tumor who underwent surgery at Loghman hospital were selected for the study between November 2016 and January 2018. The level of edema according to the classification of Ide et al., (u1995) was compared with the surgical findings with blinded results, and neurosurgeons made a qualitative assessment of tumor adhesion at the time of resection...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Nitin Shivappa, James R Hébert, Susan E Steck, Akram Safari, Fatemeh Sedaghat, Bahram Rashidkhani
Background: In Iran, colorectal cancer (CRC) is the third and fourth leading cause of cancer incidence among men and women, respectively. Diet and inflammation have been suggested as important risk factors for CRC. We examined the association between dietary inflammatory index (DII) scores and CRC in a case-control study conducted in Iran. Methods: This study included 71 CRC cases and 142 controls hospitalized for acute non-neoplastic diseases. DII scores were computed from dietary intake assessed by a previously validated food frequency questionnaire...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Somye Pouy, Fatemeh Attari Peikani, Hassan Nourmohammadi, Parisa Sanei, Asma Tarjoman, Milad Borji
Cancer poses substantial challenges to both physical and mental health of patients. On the other hand, breast cancer is one of the most common cancers among Iranian women. Therefore, the present study was conducted to investigate the effect of mindfulness-based training on psychological status and quality of life (QoL) of patients with breast cancer living in Ilam, Iran. This quasi-experimental study was performed on 66 patients diagnosed with breast cancer. The patients assigned into two groups of experimental and control...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Raafat Abdel Malek, Rita Wassef, Enas Rizk, Hoda Sabry, Nevine Tadros, Abdallah Boghdady
Background: Toxoplasmosis is one of the most important cosmopolitan life-threatening diseases in immune-compromised patients. It is caused by an intracellular protozoon: Toxoplasma gondii (T. gondii). The parasite can cause pneumonia, encephalitis or disseminated disease in immune-deficient patients and dangerous congenital anomalies in infants born to mothers infected during early pregnancies. The present study aims to evaluate the prevalence of toxoplasmosis in Egyptian cancer patients and to correlate the prevalence with type of malignancy and the different cancer treatment modalities...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Arunava Das, Harshadha K, Dhinesh Kannan S K, Hari Raj K, Bindhu Jayaprakash
Background: The intendment of this study is to determine the pursuance in – vitro anticancer activity and cytotoxicity of Syzygium aromaticum against the human cervical cancer cell line (HeLa) compared to the normal cell lines. Apoptogenic properties of DCM extract of Eugenol was determined in this entire study. Materials and Methods: HeLa cell lines were cultured in DMEM medium and incubated with different concentration of DCM – Eugenol extract. MTT assay brought out the way to determine the cell viability and quantification was done with the optical absorbance at 570 nm and 620 nm as reference...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Ranjana Solanki, Natasha Agrawal, Maryam Ansari, Shashank Jain, Arpita Jindal
Objective: Breast carcinoma is the most common malignant tumor and the leading cause of carcinoma deaths in women. Its etiology is multifactorial, implicating reproductive factors, hormonal imbalances and genetic predispositions. Studies have shown that Cycloxygenase-2 (COX-2) plays an important role in the carcinogenesis and increased expression has been regarded as a poor prognostic factor. The objective of our study is 1. To study COX-2 expression in normal breast tissue, DCIS and invasive breast cancer...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Faisal Alali, Nabil Kochaji
Objective: To investigate the proliferative activity of myoepithelial cells (MEC) in normal salivary glands (NSG) and adenoid cystic carcinomas (ACC)) Study design. Twenty -three salivary gland specimens (13 ACC, 10 NSG) were studied using double immunohistochemical labeling for α smooth muscle actin (a-SMA) and proliferative cell nuclear antigen (PCNA)). Results: There was a significant difference in PCNA reactivity in normal samples between myoepithelial cells of the parotid glands and of the submandibular glands, rates being higher in the latter...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Ahmed M Mahgoub, Manal G Mahmoud, Manal S Selim, Mohamed E EL Awady
Objective: The production of new natural pharmaceutical agents that increase the efficiency of chemotherapy without affecting the normal cells is the goal of all researchers. Therefore, the present study expects to evaluate the antioxidant and anticancer studies against MCF-7 cell lines of EPS produced by novel Egyptian marine bacterial strain. Methods: Marine bacterium was isolated, purified and identified by 16S rRNA gene amplification and sequence analyses. MHMEPS (the produced EPS) was analyzed by Fourier Transform Infra-red (FTIR), monosugars identification by HPLC, molecular weight estimation and sulfur content were determined...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Ni Putu Ayu Linda Permitasari, Satibi Satibi, Susi Ari Kristina
Background: The high prevalence of smokers in Indonesia is also increase the number of people as secondhand smokers. Secondhand smoke causes many health problems, including cancer. Thus, Indonesia will bear large number cancer burden of disease, but research on cancer related to secondhand smoking in Indonesia still does not exist. Therefore, this study aimed to determine the number of secondhand smoke attributable fractions (SAFs) of six cancers (lung, bladder, colorectal, stomach, pancreas and larynx) and burden of cancer caused by secondhand smoking in Indonesia using Disability Adjusted Life Years (DALYs) indicator...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Hossein Safizadeh, Sara Hafezpour, Parvin Mangolian Shahrbabaki
Background: Breast cancer is common among cancer diseases and the second leading cause of death among women worldwide. The breast cancer-caused death is directly associated with diagnosis time of the disease. Screening is one of the major methods for health promotion in human societies. However, many women still refuse to do the periodic screening. The present study is aimed to analyze the experiences of health volunteers in order to understand the barriers to breast cancer screening among women at southeast of Iran...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Thenmozhi K, Karthikeyani Visalakshi N, Shanthi S
Objective: In biological data analysis, protein sequence and structural motifs are an amino-acid sequence patterns that are widespread and used as tools for detecting the cancer at an earlier stage. To improve the cancer detection with minimum space and time complexity, Distribution based Fuzzy Estimate Spectral Clustering (DFESC) technique is developed. Methods: Initially, the protein sequence motifs are taken from dataset to form the cluster. The Distribution based spectral clustering is applied to group the protein sequence by measuring the generalized jaccard similarity between each protein sequences...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Gustavo Fatureto Escobar, Douglas Reis Abdalla, Marcela Beghini, Valeria Bisinoto Gotti, Virmondes Rodrigues Junior, Marcelo Henrique Napimoga, Betania Maria Ribeiro, Denise Bertulucci Rocha Rodrigues, Ruchele Dias Nogueira, Sanivia Aparecida de Lima Pereira
Aim: to compare the levels of IFN-γ, TGF-β and C-reactive protein (CRP) in healthy patients (HP) and chronic periodontitis patients (CP) before and seven days after the last session of Non-Surgical Periodontal Treatment (NSPT). Materials and Methods: 40 subjects were divided into two groups: healthy (n= 20), and with chronic periodontitis (n = 20). Serum and gingival crevicular fluid (GCF) were collected from each patient and quantified for IFN-γ, TGF-β and CRP using the enzyme-linked immunosorbent assay (ELISA)...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
S S Hasson, A S H Al-Shubi, J Z Al-Busaidi, M S Al-Balushi, F L Hakkim, L Rashan, G M Aleemallah, A A Al-Jabri
Breast and cervical cancers are global health concerns and major cause of deaths among women. Current treatments such as chemotherapy are associated with several drawbacks that limit their effectiveness. Several anticancer remedies have been found with natural products in the past and the search continues for more examples. Cytotoxic natural compounds may have considerable benefits for cancer therapy either in potentiating the impact of chemotherapy or curtailment of harmful effects. Therefore, discovery and identification of new drugs for breast and cervical cancer treatment are of high priority...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Yasuo Tsuchiya, Kumudesh Mishra, Vinay K Kapoor, Ruchira Vishwakarma, Anu Behari, Toshikazu Ikoma, Takao Asai, Kazuo Endoh, Kazutoshi Nakamura
Objective: Gallbladder cancer is the commonest gastrointestinal cancer in northern Indian women. Some studies have examined the association between Helicobacter pylori infection and gallbladder cancer risk, but findings have been inconsistent. We aimed to examine the association between H. pylori infection and gallbladder cancer in Indian people. Materials and Methods: We conducted a hospital-based case-control study including 100 gallbladder cancer patients with gallstones who were 32 to 79 years old (cases; 72 women and 28 men), and 100 cholelithiasis patients aged 14 to 75 years (controls; 65 women and 35 men)...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Ahmed Ashour Badawy, Gehan Khedr, Abbas Omar, Sejong Bae, Waleed Arafat, Stefan Grant
Background: Advanced stage non-small cell lung cancer (NSCLC) is a heterogenous disease, yet, with the exception of targeted therapies, most guidelines recommended uniform treatment irrespective of tumor burden or sites of metastases and this may explain, in part, the wide range of responses to same lines of therapy. Aim of work: In this work we tried to explore the effect of metastatic sites in on overall survival (OS), in an unselected group of Non-small cell lung cancer patients who received different treatments line...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Duc Trong Quach, Den Van Ha, Toru Hiyama
Aim: To assess the endoscopic and clinicopathological features of early-onset gastric cancer (EOGC) in Vietnamese, a population with intermediate risk of gastric cancer. Patients and methods: Consecutive patients diagnosed with gastric adenocarcinoma were prospectively recruited. The demographic, clinical data in each patient were collected. The location and macroscopic type of all gastric lesions suspected to be malignant were reported according to the Japanese classification. The histologic tumor type of gastric cancer (GC) was classified according to the Lauren classification...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Muhammad Shariq Shaikh, Zeeshan Ansar Ahmed, Mohammad Usman Shaikh, Salman Naseem Adil, Mohammad Khurshid, Tariq Moatter, Anila Rashid, Farheen Karim, Ahmed Raheem, Natasha Ali
Objectives: The heterogenous response to treatment in acute myeloid leukemia (AML) can be attributed largely to the difference in cytogenetic features identified in between cases. Cytogenetic analysis in acute leukemia is now routinely used to assist patient management, particularly in terms of diagnosis, disease monitoring, prognosis and risk stratification. Knowing about cytogenetic profile at the time of diagnosis is important in order to take critical decisions in management of these patients. The study was conducted to determine the distribution of cytogenetic abnormalities in Pakistani adult patients with AML in order to have insights regarding behavior of the disease...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Nasim Rahmani Kukia, Reza Alipanah-Moghadam, Nowruz Delirezh, Mohammad Mazani
Background: Immunotherapy is one promising therapeutic strategy against glioma, an aggressive form of brain cancer. Previous studies have demonstrated that multiple tumor antigens exist and can be used to induce tumor specific T cell responses. Furthermore, recently it was shown that TLR4-primed mesenchymal stem cells (MSCs), also known as MSC1, mostly elaborate pro-inflammatory mediators. Compared to MSCs, MSC-derived microvesicles (MVs) have advantageous properties that present them as stable, long lasting effectors with no risk of immune rejection...
July 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
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