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Asian Pacific Journal of Cancer Prevention: APJCP

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https://www.readbyqxmd.com/read/28612601/classification-of-bladder-cancer-patients-via-penalized-linear-discriminant-analysis
#1
Hadi Raeisi Shahraki, Peyman Bemani, Maryam Jalali
Objectives: In order to identify genes with the greatest contribution to bladder cancer, we proposed a sparse model making the best discrimination from other patients. Methods: In a cross-sectional study, 22 genes with a key role in most cancers were considered in 21 bladder cancer patients and 14 participants of the same age (± 3 years) without bladder cancer in Shiraz city, Southern Iran. Real time-PCR was carried out using SYBR Green and for each of the 22 target genes 2-Δct as a quantitative index of gene expression was reported...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612600/descriptive-epidemiological-analysis-of-thyroid-cancer-in-the-saudi-population-2001-2013
#2
Bandar Alshehri
Objective: Thyroid cancer has one of the highest frequency rates among thyroid diseases, and ranks second for neoplasia in the Saudi female population. This paper concerns a comprehensive evaluation of increasing incidence trends and geographical distribution of different patterns of thyroid cancer among the Saudi Arabian population using the latest Saudi Cancer Registry (SCR) reports. Methods: The analysis included a total of 7,670 thyroid cancer cases (1604 male and 6066 female) which were recorded in the SCR files for the period between January 2001 and December 2013...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612599/tobacco-use-prevention-for-the-young-tupy-s-development-validity-and-reliability-of-an-interactive-multimedia-strategy-from-the-adolescents%C3%A2-perspective-in-malaysia
#3
Faridah Mohd Zin, Azlin Hilma Hillaluddin, Jamaludin Mustaffa
Objective: This study aims to develop, validate and determine the reliability of an interactive multimedia strategy to prevent tobacco use among the young (TUPY-S) from an adolescents’ perspective. Methods: A descriptive study design was utilized. A modular instruction guideline by Russel (1974) was followed in the entire process, comprising a feasibility study, a review of existing modules, specification of the objectives, identification of the construct criterion items, learner analysis and entry behavior specification, establishment of the sequence instruction and media selection, a tryout with students and a field test...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612598/relationship-between-breast-cancer-and-oral-contraceptive-use-among-thai-premenopausal-women-a-case-control-study
#4
Wisit Chaveepojnkamjorn, Natchaporn Pichainarong, Rungsinoppadol Thotong, Pratana Sativipawee, Supachai Pitikultang
Background: Breast cancer (BC) is an important issue both in medicine and public health as it is the leading malignancy with high incidence and mortality among women worldwide. The objective of this research was to determine the associations of BC with oral contraceptive (OC) use among Thai premenopausal women (TPW). Materials and Methods: A case-control study was conducted among TPW attending the National Cancer Institute, with 257 cases and 257 controls in 2013-2014. Cases and controls were matched by age (± 5 years), residential area and duration of attendance...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612597/men-have-a-higher-incidence-of-seroma-after-breast-cancer-surgery
#5
Letícia Lima de Oliveira, Suzana Sales de Aguiar, Paulo Franscisco Mascarenhas Bender, Anke Bergmann, Luiz Claudio Santos Thuler
Background and Objectives: Male breast cancer (MBC) is rare. While surgical treatment may result in several complications in women, little is known about how it affects men. The objective of this study was to compare the incidence of postoperative wound complications between men and women after breast cancer surgery. Methods: This cohort study included all male patients enrolled for breast cancer surgical treatment at the Brazilian National Cancer Institute, between 1999 and 2013. Each was matched with three female breast cancer patients...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612596/prognostic-value-of-the-neutrophil-to-lymphocyte-ratio-nlr-in-lung-cancer-cases
#6
Berna Akinci Ozyurek, Tugce Sahin Ozdemirel, Sertac Buyukyaylaci Ozden, Yurdanur Erdogan, Bekir Kaplan, Tugba Kaplan
Haemogram assessment is a cheap and easy method which can be readily performed for almost all patients. Leucocyte, neutrophil and lymphocyte counts and the neutrophil to lymphocyte ratio (NLR) are markers of systemic inflammation. We here aimed to evaluate haemogram parameters of our patients with lung cancer according to the pathologic diagnosis of small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Materials and Methods: The study included 386 patients diagnosed with lung cancer in our hospital between January 2006 and January 2014...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612595/trends-in-female-breast-cancer-by-age-group-in-the-chiang-mai-population
#7
Patumrat Sripan, Hutcha Sriplung, Donsuk Pongnikorn, Shama Virani, Surichai Bilheem, Udomlak Chaisaengkhaum, Puttachart Maneesai, Narate Waisri, Chirapong Hanpragopsuk, Panrada Tansiri, Varunee Khamsan, Malisa Poungsombat, Aumnart Mawoot, Imjai Chitapanarux
Objectives: This study was conducted to determine incidence trends of female breast cancer according to age groups and to predict future change in Chiang Mai women through 2028. Method: Data were collected from all hospitals in Chiang Mai in northern Thailand, from 1989 through 2013, and used to investigate effects of age, year of diagnosis (period) and year of birth (cohort) on female breast cancer incidences using an age-period-cohort model. This model features geometric cut trends to predict change by young (<40 years), middle-aged (40-59) and elderly (≥60) age groups...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612594/validation-of-eortc-in-patsat-32-in-morocco-methods-and-processes
#8
Majdouline Obtel, Zineb Serhier, Karima Bendahhou, Maria Bennani, Ahmed Zidouh, Abdellatif Benider, Hassan Errihani, Rachid Bekkali, Chakib Nejjari
Background. The EORTC IN-PATSAT32 questionnaire was developed by the EORTC Quality of Life (QL) Group to assess the satisfaction of patients affected by cancer and hospitalized in oncology centers. The aim of this study is to assess the psychometric properties of the EORTC IN-PATSAT32 administered to Moroccan patients. Methods. A total of 133 hospitalized patients affected by cancer in different sites completed the translated EORTC IN-PATSAT32 questionnaire in oncology hospitals. The internal consistence reliability, reproducibility and construct validity were assessed...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612593/2-methoxyestradiol-promotes-radiosensitivity-of-esophageal-squamous-cell-carcinoma-by-suppressing-hypoxia-inducible-factor-1%C3%AE-expression
#9
Yanrong Lu, Jia Song, Zhabihula Baerxiaguli, Zengyan Li, Min Wu, Jinrong Zhang
Background: Acquired radioresistance remains a primary obstacle to improving survival of patients with esophageal cancer(EC). Factors related to hypoxia play crucial roles in such radioresistance, such as hypoxia-inducible factor 1α (HIF-1α), vascular endothelial growth factor (VEGF) and angiogenic factor with G-patch and FHA domains 1 (AGGF1). However, evidence clarifying the role of AGGF1 in EC is limited. We here aimed to investigate the effects of 2-methoxyestradiol(2ME2) on the radiosensitivity of EC...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612592/using-health-belief-model-constructs-to-examine-differences-in-adherence-to-pap-test-recommendations-among-iranian-women
#10
Mahmood Karimy, Hossein Azarpira, Marzieh Araban
Despite documented successful Pap tests in routine care of women, screening levels are unfortunately often lower than recommended. This study aimed to assess differences in adherence to Pap test guidelines among a sample of Iranian women using the Health Belief Model (HBM). In this descriptive and analytical study, information was collected from a total of 305 women, (age range of 15-49) from Zarandieh health centers in Iran using a random multistage sampling method. The questionnaire covered demographic characteristics; health belief model constructs were gathered by a self-report method...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612591/clinical-signif%C3%A4-cance-of-serum-ykl-40-chitinase-3-like-1-protein-as-a-biomarker-in-melanoma-an-analysis-of-112-turkish-patients
#11
Kayhan Erturk, Faruk Tas, Murat Serilmez, Elif Bilgin, Vildan Yasasever
Background: Angiogenesis plays an essential role in tumor growth and serum levels of YKL-40 , a strong angiogenic factor that promotes tumor vessel development, has been found to be elevated in various cancers. We here investigated correlation between melanoma parameters and serum YKL-40 levels, to assess potential diagnostic, prognostic and predictive values. Material and Methods: Data for 112 pathologically confirmed cutaneous melanomas of any stage were examined retrospectively. ELISA assays were used to measure serum YKL-40 in plasma samples...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612590/treatment-planning-with-unflattened-as-compared-to-flattened-beams-for-bilateral-carcinoma-of-the-breast
#12
Suresh Tamilarasu, Madeswaran Saminathan, S K Sharma, Anjali P, Abhinav Dewan
Aim: To evaluate the plan quality of 6MV unflattened (UFB) and flattened beam (FB) photon energy using AAA dose calculation algorithms for volumetric arc therapy. Materials and Methods: Plans were generated for bilateral carcinoma of breast and the dose prescribed was 50.4Gy in 28 fractions. Two different plans were made for each patient using 6MV FB and 6MV UFB. Dose calculations were performed on an AAA dose calculation algorithm. Plans were generated on Eclipse TPS and were capable of being delivered with a true beam STx linear accelerator...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612588/analysis-of-knowledge-level-in-brasilian-students-about-human-papillomavirus-infection-and-development-of-penile-cancer
#13
George Kemil Abdalla, Emanuella Francisco Fajardo, Bruno Belmonte Martinelli Gomes, Thiago Mantello Bianco, Ana Karina Marques Salge, Eduardo Elias Vieira de Carvalho, Marlize Moura Dos Reis, Dayana Pousa Siqueira Abrahão, Douglas Reis Abdalla
Introduction: Human papillomavirus (HPV), belonging to the Papovavirida family, is the most prevalent sexually transmitted disease (STD) agent worldwide. In Brazil, it is estimated that there are 3-6 million people infected with HPV. Aim: The aim of this study was to evaluate the knowledge of young male students about penis cancer related to HPV infection. Methods: This exploratory and quantitative study was conducted to analyze answers of 242 male students attending a private college located in Uberaba city, Minas Gerais state, Brazil, during 2015...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612587/%C3%A2-menthol-induces-reversal-of-promoter-hypermethylation-and-associated-up-regulation-of-the-fancf-gene-in-the-siha-cell-line
#14
Gaurav Parashar, Nidarshana Chaturvedi Parashar, Neena Capalash
Objective: To identify natural bioactive molecules with potential to inhibit DNA methyltransferase 1 (DNMT1) and cause reactivation of genes silenced due to promoter hypermethylation. Methods and Results: -(-) Menthol and epigallocatechin-3-gallate (EGCG) (reference molecule) were investigated using an in vitro methylation assay, which indicated potential of –(-)menthol as an epigenetic modulator with the ability to directly inhibit M.SssI (an analogue of DNMT1) activity at 100μM. Methylation specific PCR and bisulphite sequencing revealed complete hypomethylation of 15 CpG sites in the Fanconi anemia, complementation group F (FANCF) gene between +280 and + 432 nucleotides relative to the transcription start site, which resulted in significant (P<0...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612586/sociological-transition-and-breast-cancer-in-the-arab-world-the-experience-of-lebanon
#15
Najla A Lakkis, Salim M Adib, Ghassan Hamadeh, Rana El Jarrah, Mona H Osman
Background: Breast cancer is the leading cause of cancer death among females in Lebanon. This study aimed at analyzing its epidemiology in the country over time. Methods: Data were extracted from the Lebanese National Cancer Registry (NCR) for the years 2004 through 2010. Age-standardized and age-specific incidence rates for cancers per 100,000 population were calculated. Results: Breast cancer ranked first, accounting for an average of 37.6% of all new female cancer cases in Lebanon during the period of 2004-2010...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612585/pancreatic-cancer-is-associated-with-peripheral-leukocyte-oxidative-dna-damage
#16
Ashraf Mohamadkhani, Akram Pourshams, Jessica Viti, Filippo Cellai, Kamran Mortazavi, Maryam Sharafkhah, Masoud Sotoudeh, Reza Malekzadeh, Paolo Boffetta, Marco Peluso
Background: DNA damage accumulation has been linked to the cancer phenotype. The purpose of this study was to compare the levels of DNA base 8-hydroxy-2′-deoxyguanosine (8-OHdG) and C-reactive protein (CRP) inflammatory markers in healthy controls and pancreatic cancer patients from a hospital-based case-control study. Materials and Methods: Fifty-five pancreatic cancer patients and 55 healthy controls were enrolled from a pool of patients referred to the Endoscopic Ultrasound (EUS) center. Analysis of DNA content of peripheral blood cells was conducted for 8-OHdG with the 32P-postlabelling assay...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612580/new-genetic-variation-in-bcr-gene-of-major-b3a2-breakpoint-bcr-abl-fusion-gene-in-patients-with-chronic-myelogenous-leukemia-in-yogyakarta-indonesia
#17
Tri Agusti Sholikah, Susanna Hilda Hutajulu, Dewi Sulistyawati, Sumartiningsih Aning, Sri Fatmawati, Anditta Syifarahmah, Kartika Widayati, Johan Kurnianda, Dewi Kartikawati Paramita
Background: Polymorphic bases in several exons of the BCR gene have been found in several studies of the BCR-ABL fusion gene . Most of the polymorphisms do not have any implications for the primary structure of the BCR-ABL protein. Nucleotide changes are often located in the area close to the fusion region, and therefore may influence primer annealing. Our previous work failed to amplify 15 of 200 samples from BCR-ABL positive chronic myelogenous leukemia (CML) patients using multiplex PCR, the standard method to detect BCR-ABL transcripts used in our institution...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612284/detection-of-high-risk-human-papillomavirus-genotypes-16-and-18-in-head-and-neck-squamous-cell-carcinomas-in-jordan
#18
Luay Abu Qatouseh, Israr Sabri, Imad Alkhatib, Eiad Atwa, Tawfiq Arafat
Background: Recently, associations of the human papillomavirus (HPV) with head and neck cancer have become well established. Of particular concern, the severity and pathological outcomes of squamous cell carcinomas are remarkably affected by the genotypes of HPV present in such lesions. This study was conducted to investigate the occurrence of HPV genotypes, particularly high risk 16 and 18, among oral and laryngeal squamous cell carcinomas in Jordan. Methods: During the period of May 2015 to March 2016, we evaluated a total of 108 paraffin-embedded tissue samples, histologically confirmed as SCC, of both oral and laryngeal tumors for the presence of HPV DNA...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28610966/smoking-habits-among-greek-university-students-after-the-financial-crisis
#19
Maria Saridi, Anastasia Nanou, Christos Vasilopoulos, Michael Kourakos, Efstathios Skliros, Aikaterini Toska, Kyriakos Souliotis
Background: University students worldwide seem to have increased rates of smoking, alcohol abuse, binge drinking episodes and harmful consumption trends, raising a serious public health issue. The aim of the present study was to investigate university students’ smoking habits and exposure to secondary smoke amid a financial crisis. Methods: The present descriptive, correlational analysis was conducted at the University of Peloponnese. Results: The average age of the sample (n=203) was 24.9 years (±7.6 years) with 36...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28610421/electro-acupuncture-therapy-increases-serum-interferon-%C3%AE-levels-in-rats-with-7-12-dimethylbenz-%C3%AE-anthracene-dmba-induced-breast-tumors
#20
Laily Yuliatun, Sholihatul Amalia, Aliyah Adek Rahma, Laily Aflahal Yaumi
Objective: To determine the effect of electro-acupuncture (EA) treatment on serum levels of interferon-γ (IFN-γ) in rats with 7,12-dimethylbenz(α)anthracene (DMBA)-induced breast tumors. Methods: Twenty five female Wistar rats were divided randomly into 5 groups: normal group (N; neither DMBA-induced nor treated with EA); control group (C; DMBA-induced only); EA 3 days : (DMBA-induced + EA for 3 days); EA 5 days: (DMBA-induced + EA for 5 days); EA 10 days: (DMBA-induced + EA for 10 days) group. Animals were acclimatized from day 1 to day 7...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
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