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Asian Pacific Journal of Cancer Prevention: APJCP

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https://www.readbyqxmd.com/read/27910901/risk-factors-for-endometrial-cancer-results-from-a-hospital-based-case-control-study
#1
Maryam Ghanbari Andarieh, Mouloud Agajani Delavar, Dariush Moslemi, Sedighe Esmaeilzadeh
Objectives: The purpose of this investigation was to examine the association between endometrial cancer and possible etiological agents. Methods: A case-control study was conducted in Iran between March 2012 and May 2016. The demographic and reproductive factors of 205 women with endometrial cancer were compared, and 590 healthy cases were participated in the control group. For each endometrial cancer case, there were three controls, who were matched in terms of age and residence. The data were considered significant at p ≤0...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893212/effects-of-energy-conservation-strategies-on-cancer-related-fatigue-and-health-promotion-lifestyle-in-breast-cancersurvivors-a-randomized-control-trial
#2
Elham Sadeghi, Nahid Gozali, Fatemeh Moghaddam Tabrizi
Purpose: Cancer-related fatigue is frequently experienced by patients during and after therapy. The present study was conducted to assess the impact of energy conservation strategies and health promotion in breast cancer survivors. Methods: A randomized controlled trial was carried out to compare the intervention effect (n=69.0) with controls (n=66.0) based on routine oncology ward care. The intervention was five weekly sessions for groups of 6-8 breast cancer survivors. Data on fatigue and health promotion lifestyle were obtained before and after completion the intervention and then 8 weeks later for analysis of variance (ANOVA) with repeated measures...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893211/changes-in-the-distribution-of-cancer-incidence-in-nepal-from-2003-to-2013
#3
Krishna Kanta Poudel, Zhibi Huang, Prakash Raj Neupane, Roberta Steel
Background: Cancer incidence data are vital for cancer control planning in any nation. This retrospective study was conducted to compare the cancer incidence of all sites between the first cancer registry report and the most recent example in Nepal. Material and Methods: The cases in the first (2003) and latest (2013) national cancer registry reports, accumulated by all the hospital based cancer registries in Nepal were taken for the research. The frequencies, crude incidences and age specific incidences (per 100,000) of the five major cancers were calculated for both males and females...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893210/impact-of-treatment-type-on-overall-survival-in-elderlybrazilian-women-with-breast-cancer
#4
Marcelo Adeodato Bello, Raquel Ferreira de Menezes, Brunna Silva, Rafael de Carvalho da Silva, Rousiane Silva Cavalcanti, Thayane de Fátima da Costa Moraes, Fabiana Tonellotto, Suzana Sales de Aguiar, Renata Brum Martucci, Anke Bergmann, Luiz Claudio Thuler
Objective: To analyze the survival of elderly patients with breast cancer according to the type of treatment used. Methods: A cohort study of women aged 80 or over with breast cancer registered with the Brazilian National Cancer Institute (Instituto Nacional do Câncer - INCA) between 2008 and 2009 was conducted. Prognosis was analyzed according to the cancer treatment performed: surgery, radiotherapy, or hormone therapy. Analysis of the overall 5-year survival rate was performed using the Kaplan - Meier method, and comparisons of curves were undertaken using the log-rank test...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893209/determination-of-metal-levels-in-shamma-smokeless-tobacco-with-inductively-coupled-plasma-mass-spectrometry-icp-ms-in-najran-saudi-arabia
#5
Eid Ibrahim Brima
Objective: The use of Shamma (smokeless tobacco) by certain groups is giving rise to health problems, including cancer, in parts of Saudi Arabia. Our objective was to determine metals levels in Shamma using inductively coupled plasma mass spectrometry (ICP-MS). Methods: Thirty-three samples of Shamma (smokeless tobacco) were collected, comprising four types: brown Shamma (n = 14.0), red Shamma (n = 9.0), white Shamma (n = 4.0), and yellow Shamma (n = 6.0). All samples were collected randomly from Shamma users in the city of Najran...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893208/enterolactone-reduces-telomerase-activity-and-levels-of-its-catalytic-subunit-in-breast-cancer-cells
#6
Davod Ilbeigi, Mitra Nourbakhsh, Shahnaz Khaghani, Nahid Einollahi, Nejat kheiripour, Zafar Gholinejad, Mohammad Alaee, Mostafa saberian
Background: Dietary consumption of phytoestrogens including lignans are linked to a lower incidence of breast cancer. Since activation of telomerase is crucial for growth of cancer cells, the aim of this study was to examine the effect of enterolactone (ENL) and enterodiol (END) on this enzyme. Methods: MTT assays were performed to determine the effect of different concentrations of ENL and ENL on cell viability and to determine the effective concentrations of these two compounds for inhibition of cell growth...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893207/prevalence-and-risk-factors-for-helicobacter-pylori-infection-among-healthy-inhabitants-in-northern-jakarta-indonesia
#7
Yasuyuki Goto, Ari Fahrial Syam, Nikko Darnindro, Florentina Carolin Puspita Hapsari
Background: The prevalence of Helicobacter pylori (H. pylori) infection in Indonesia has been reported to be exceedingly low. The purpose of our study was to confirm whether this is the case in Northern Jakarta using a sensitive 13C-urea breath test (UBT), and to examine any associations with lifestyle/environment factors and potential routes of transmission. Methods: We recruited a total of 196 subjects from a low-income community in Northern Jakarta, Indonesia, data from 193 who completed a questionnaire about their lifestyle/environment and had UBT being included as the final...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893206/no-significant-association-between-human-papillomavirus-and-breast-cancer-sanandaj-iran
#8
Maryam Karimi, Mazaher Khodabandehloo, Bahram Nikkhoo, Ebrahim Ghaderi
Background and Objective: Any role of human papillomavirus (HPV) in the development of breast cancer is conjectural. The aim of this study was to investigate possible links between HPV and breast cancer in women, Sanandaj, Iran. Methods: In this case-control study, 70 formalin fixed and paraffin embedded blocks of breast malignant tumors as a case group and 70 blocks of lesions without malignancy were selected as controls. Sections about 10 μm thick were prepared. After removing the paraffin, DNA was extracted...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893205/patterns-of-recurrence-after-resection-of-mass-forming-type-intrahepatic-cholangiocarcinomas
#9
Vor Luvira, Chalerm Eurboonyanun, Vajarabhongsa Bhudhisawasdi, Ake Pugkhem, Chawalit Pairojkul, Varisara Luvira, Egapong Sathitkarnmanee, Kulyada Somsap, Supot Kamsa-ard
Background: Intrahepatic cholangiocarcinoma (IHCCA) is an aggressive tumor for which surgical resection is a mainstay of treatment. However, recurrence after resection is common associated with a poor prognosis. Studies regarding recurrence of mass-forming IHCCA are rare; therefore, we investigated the pattern with our dataset. Methods: We retrospectively reviewed the medical and pathological records of 50 mass-forming IHCCA patients who underwent hepatic resection between January 2004 and December 2009 in order to determine the patterns of recurrence and prognosis...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893204/estimating-the-economic-burden-of-lung-cancer-in-iran
#10
Satar Rezaei, Ali Akbari Sari, Abraha Woldemichael, Moslem Soofi, Ali Kazemi, Behzad Karami Matin
Objectives: Lung cancer is a major public health problem and one of the most costly illnesses. The study aimed to estimate the economic burden of lung cancer in Iran in 2014. Methods: A cross-sectional study was conducted to estimate the direct and indirect costs for patients with lung cancer using a prevalence-based approach. A human capital approach was employed to estimate the indirect costs. Data were obtained from several sources such as through patient interview using structured questionnaire, medical records, the GLOBOCAN databases, the Iranian Statistical Center, the Iranian Ministry of Cooperation, Labor and Social Welfare, and the Institute for Health Metrics and Evaluation (IHME)...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893203/high-mortality-rate-of-stomach-cancer-caused-not-by-high-incidence-but-delays-in-diagnosis-in-aomori-prefecture-japan
#11
Masashi Matsuzaka, Rina Tanaka, Yoshihiro Sasaki
Background: There are substantial differences in the mortality rates of stomach cancer among the 47 prefectures in Japan, and Aomori prefecture is one of the most severely impacted. The aims of this study were to determine the incidence and mortality rates of stomach cancer in Aomori prefecture in comparison with Japan as a whole and cast light on reasons underlying variation. Methods: Data on stomach cancer cases were extracted from the Aomori Cancer Registry Database. Incidence rates for specific stages at the time of diagnosis were cited from Monitoring of Cancer Incidence in Japan, and mortality rates for stomach cancer in Aomori prefecture and the whole of Japan were obtained from Vital Statistics...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893202/role-of-gstm1-copy-number-variant-in-the-prognosis-of-thai-colorectal-cancer-patients-treated-with-5-fu-based-chemotherapy
#12
Tanett Pongtheerat, Pensri Saelee
Background: Glutathione S-transferase M1 (GSTM1) is involved in the detoxification of carcinogenic agents. DNA copy number variants of GSTM1 may be associated with cancer progression and may result in reduced survival time of various cancers. Determination of DNA copy number variants was here used to assess the association between GSTM1 copy number variant and pathological status and survival time of colorectal-cancer patients treated with 5-fluorouracil-based chemotherapy. Methods: One hundred thirteen Thai colorectal-cancer patients were investigated for GSTM1 copy number variant by real-time PCR...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893201/effects-of-tobacco-smoking-on-the-dorsum-of-the-tongue-and-buccal-epithelium
#13
Abdullah Faraj Al Shammari, Ibrahim Khalil AL Ibrahim, Amjad Ibrahim Alaauldeen, Randa Fouad Merza, Hussain Gadelkarim Ahmed
Objective: The aim of this study was to assess the effects of tobacco smoking on the dorsum of the tongue and buccal epithelium. Methodology: This case control cross-sectional study was conducted with 174 smoking and non-smoking volunteers living in the city of Hail, Northern KSA. Cytological Materials were obtained from buccal mucosa and dorsum of the tongue, and assessed using cytopathological methods. Results: In buccal smears, cytological atypia was observed in 17 out of 101 (16.8%) smoker cases but only 3/73(4...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893200/clinical-impact-of-overexpression-of-foxp3-and-wt1-on-disease-outcome-in-egyptian-acute-myeloid-leukemia-patients
#14
Magda Assem, Ahmed Osman, Eman Kandeel, Reham Elshimy, Hanan Nassar, Radwa Ali
Background: In the last decade, it has become clear that change of gene expression may alter the hematopoietic cell quiescent state and consequently play a major role in leukemogenesis. WT1 is known to be a player in acute myeloid leukemia (AML) and FOXP3 has a crucial role in regulating the immune response. Objectives: To evaluate the impact of overexpression of WT1and FOXP3 genes on clinical course in adult and pediatric AML patients in Egypt. Patients and methods: Bone marrow and peripheral blood samples were obtained from 97 de novo non M3 AML patients (63 adult and 34 pediatric)...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893199/prognostic-factors-in-stage-iii-non-small-cell-lung-cancer-patients
#15
Semiha Elmaci Urvay, Birsen Yucel, Eda Erdis, Nedim Turan
Aim: The objective of this study is to investigate prognostic factors affecting survival of patients undergoing concurrent or sequential chemoradiotherapy (CRT) for stage III non-small-cell lung cancer (NSCL). Methods and materials: We retrospectively reviewed the clinical records of 148 patients with advanced, inoperable stage III NSCLC, who were treated between 2007 and 2015. Results: The median survival was found to be 19 months and 3-year overall survival was 27%. Age (<65 vs ≥65 years, p=0.026), stage (IIIA vs IIIB, p=0...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27893198/clinical-application-of-ultrasound-guided-thyroid-fine-needle-aspiration-biopsy-and-thinprep-cytology-test-in-diagnosis-of-thyroid-disease
#16
Ying Wei, Yao Lu, chenxi li
Purpose: To study the clinical application value of ultrasound guided thyroid fine needle aspiration biopsy and thinprep cytology testing in diagnosis of thyroid disease. Methods: A total of 78 patients with thyroid nodules were enrolled, 34 males and 44 females, aged 33-64 years old with mean age of 47.6 years. All underwent thyroid module fine needle puncture after surgery to assess cell pathology and histopathological features. Results: Sufficient specimens were obtained from all of 78 patients, the cytological results of 73 cases (93...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27892965/diabetes-mellitus-and-risk-of-colorectal-cancer-mortality-in-japan-the-japan-collaborative-cohort-study
#17
Ce Tan, Mitsuru Mori, Yasushi Adachi, Kenji Wakai, Sadao Suzuki, Koji Suzuki, Shuji Hashimoto, Yoshiyuki Watanabe, Akiko Tamakoshi
Objective: Our aim was to estimate whether diabetes mellitus (DM) may be associated with an increased risk of colorectal cancer (CRC) mortality in Japan. Methods: The Japan Collaborative Cohort (JACC) Study is a nationwide prospective study, initiated in 1988, which involves 110,585 subjects (age range: from 40 to 79 years; 46,395 males and 64,190 females). Our present analysis population comprised 96,081 (40,510 men and 55,571 women) who provided details on DM history. The questionnaire also included age, sex, weight, height, family history of CRC, smoking, drinking and exercise habits, and education...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27892939/postoperative-survival-according-to-the-glasgow-prognostic-score-in-patients-with-resected-lung-adenocarcinoma
#18
Yuichiro Machida, Motoyasu Sagawa, Makoto Tanaka, Nozomu Motono, Takuma Matsui, Katsuo Usuda, Hidetaka Uramoto
Background: The Glasgow Prognostic Score (GPS) is calculated from measured CRP and albumin levels. We here evaluated the significance of the GPS in patients with resected pulmonary adenocarcinoma. Materials and Methods: The present study included 156 patients with lung adenocarcinoma who underwent lobectomy at Kanazawa Medical University between 2002 and 2012. Classification was into three groups: those with normal albumin (>=3.5 g/dl) and C-reactive protein (CRP) (<=1.0 mg/dl) levels were classified as GPS 0 (n =136), those with low albumin (<3...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27892682/can-serum-icam-1-distinguish-pancreatic-cancer-from-chronic-pancreatitis
#19
amal mohamed, Yasmine Saad, Doaa Saleh, Rehab Elawady, Rasha Eletreby, Ahmad Khairalla, Eman Badr
Background and aim: Pancreatic cancer is the fourth leading cause of cancer-related death worldwide, with an overall 5-year survival of <5% mainly due to presence of advanced disease at time of diagnosis. Therefore development of valid biomarkers to diagnose pancreatic cancer in early stages is an urgent need. This study concerned the sensitivity and specificity of serum ICAM 1 versus CA 19-9 in differentiation between pancreatic cancer and healthy subjects and acohort of patients with chronic pancreatitis with a focus on assessing validity in diagnosis of early stages of pancreatic cancer...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27892681/evaluating-the-existence-of-small-compressed-binucleated-squamous-cells-in-asc-h
#20
Mitsuaki Okodo, Kaori Okayama, Hiroshi Kitamura, Natsuko Shiina, Timothy Caniz, Midori Ono, Hiromi Yabusaki
Purpose: To evaluate the legitimacy of a diagnosis of ASC-H in 5 cases which were followed up monthly for over 2 years with both cytology and HPV testing. Methods: Some 5 cases out of a total of 25.0 self-sampled Pap test patients diagnosed as ASC-H provided 119 specimens over 2 years, with HPV-DNA testing perormed using a E6 primer. Results: Cases 1, 2 and 3 showed SIL after the ASC-H diagnosis, while cases 4 and 5 showed and maintained NILM. Cases 1, 2 and 3 were further characterized by small atypical compressed binucleated cells, in which HPV was detected by in situ PCR...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
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